biology screencast- cell division

7/25/2019 Biology Screencast- Cell Division

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Cell

Division(Cyclic Dependent Kinase)

Ruha Reddy, Emily Ren, NithyaSanthosh, Vijay Srivastava,Alex Wu


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Intro to Cell Control

- Mature (ex. Kidney and Nerve Cells) vs. Constantly renewed cells

tissue lining intestines)

- Response to Environmental Conditions

- Normal human liver cells vs.amaged liver- !nicellular organisms" #acteria$ archaea$ yeasts divide %aster i% the environment is rich with

- Cancer - de%ects in cell division control & uncontrolled$ cancerous


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Overview of !"# itosis Re$u

- Maturation-promoting-%actor (M') - induces mitosis in all euary

- *ow +t ,ors"- Contains distinct units" Protein Kinaseand Cyclin (present in uctuating con- Cyclin is regulatory protein activates 'rotein Kinase (Cd) cataly/es phos

other proteins induce mitosis- Negative eed#ac - M' activates an

en/yme complex that triggers its owndestruction

- More cyclin & more cell division & morecells


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!" % Cy&lin 'e(endent )inase


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*umor Su((ressor +ene# (-

- 0umor suppressor gene" inhi#its cell division #1c proteins that are

prevent uncontrolled cell growth

- 2ctivates other genes"

- 2ctivatep21gene" halts cell cycle #y #inding to Cds allows time %or the cell to repair N2- 2ctivate expression o% a group o% miRN2s inhi#it the cell cycle- 2ctivates 3suicide4 genes protein productions #ring a#out apoptosiswhen N2 damage is irrepa


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Proto-oncogene


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Con&lusion

biology screencast- cell division

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