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Biochemistry Lecture 5

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Page 1: Biochemistrybonhamchemistry.com/wp-content/uploads/2015/07/Lecture_5.pdfLehninger Principles of Biochemistry, Fifth Edition 2008 W. H. Freeman and Company . 100 75 50 25 200 o 400

Biochemistry

Lecture 5

Page 2: Biochemistrybonhamchemistry.com/wp-content/uploads/2015/07/Lecture_5.pdfLehninger Principles of Biochemistry, Fifth Edition 2008 W. H. Freeman and Company . 100 75 50 25 200 o 400

Proteins

Lipids

Page 3: Biochemistrybonhamchemistry.com/wp-content/uploads/2015/07/Lecture_5.pdfLehninger Principles of Biochemistry, Fifth Edition 2008 W. H. Freeman and Company . 100 75 50 25 200 o 400

Enzymes

Page 4: Biochemistrybonhamchemistry.com/wp-content/uploads/2015/07/Lecture_5.pdfLehninger Principles of Biochemistry, Fifth Edition 2008 W. H. Freeman and Company . 100 75 50 25 200 o 400

Ribozymes

Page 5: Biochemistrybonhamchemistry.com/wp-content/uploads/2015/07/Lecture_5.pdfLehninger Principles of Biochemistry, Fifth Edition 2008 W. H. Freeman and Company . 100 75 50 25 200 o 400

Amino Acids

Page 6: Biochemistrybonhamchemistry.com/wp-content/uploads/2015/07/Lecture_5.pdfLehninger Principles of Biochemistry, Fifth Edition 2008 W. H. Freeman and Company . 100 75 50 25 200 o 400
Page 7: Biochemistrybonhamchemistry.com/wp-content/uploads/2015/07/Lecture_5.pdfLehninger Principles of Biochemistry, Fifth Edition 2008 W. H. Freeman and Company . 100 75 50 25 200 o 400

R Groups

Page 8: Biochemistrybonhamchemistry.com/wp-content/uploads/2015/07/Lecture_5.pdfLehninger Principles of Biochemistry, Fifth Edition 2008 W. H. Freeman and Company . 100 75 50 25 200 o 400
Page 9: Biochemistrybonhamchemistry.com/wp-content/uploads/2015/07/Lecture_5.pdfLehninger Principles of Biochemistry, Fifth Edition 2008 W. H. Freeman and Company . 100 75 50 25 200 o 400

Additional Amino Acids

4-hydroxyproline

5-hydroxylysine

Page 10: Biochemistrybonhamchemistry.com/wp-content/uploads/2015/07/Lecture_5.pdfLehninger Principles of Biochemistry, Fifth Edition 2008 W. H. Freeman and Company . 100 75 50 25 200 o 400
Page 11: Biochemistrybonhamchemistry.com/wp-content/uploads/2015/07/Lecture_5.pdfLehninger Principles of Biochemistry, Fifth Edition 2008 W. H. Freeman and Company . 100 75 50 25 200 o 400
Page 12: Biochemistrybonhamchemistry.com/wp-content/uploads/2015/07/Lecture_5.pdfLehninger Principles of Biochemistry, Fifth Edition 2008 W. H. Freeman and Company . 100 75 50 25 200 o 400

Peptides

Page 13: Biochemistrybonhamchemistry.com/wp-content/uploads/2015/07/Lecture_5.pdfLehninger Principles of Biochemistry, Fifth Edition 2008 W. H. Freeman and Company . 100 75 50 25 200 o 400
Page 14: Biochemistrybonhamchemistry.com/wp-content/uploads/2015/07/Lecture_5.pdfLehninger Principles of Biochemistry, Fifth Edition 2008 W. H. Freeman and Company . 100 75 50 25 200 o 400
Page 15: Biochemistrybonhamchemistry.com/wp-content/uploads/2015/07/Lecture_5.pdfLehninger Principles of Biochemistry, Fifth Edition 2008 W. H. Freeman and Company . 100 75 50 25 200 o 400
Page 16: Biochemistrybonhamchemistry.com/wp-content/uploads/2015/07/Lecture_5.pdfLehninger Principles of Biochemistry, Fifth Edition 2008 W. H. Freeman and Company . 100 75 50 25 200 o 400

oxytocin

vasopressin

Cys

Tyr

Phe Gln

Asn

Cys

SS

H2NO

NH2CGlyArgPro

Cys

Tyr

Ile Gln

Asn

Cys

SS

H2NO

NH2CGlyLeuPro

Page 17: Biochemistrybonhamchemistry.com/wp-content/uploads/2015/07/Lecture_5.pdfLehninger Principles of Biochemistry, Fifth Edition 2008 W. H. Freeman and Company . 100 75 50 25 200 o 400

CH C NH CCH OH

O O

CH 2

OO

HH

NHCCHNHCCHNH

O

HO

NH2

C

Tyr–Gly–Gly–Phe–Met Methionine enkephalin

CH2CHCH3

CH3Morphine

O

N

HO OH

CH3

H

H

Tyr–Gly–Gly–Phe–Leu Leucine enkephalin

Enkephalins

Page 18: Biochemistrybonhamchemistry.com/wp-content/uploads/2015/07/Lecture_5.pdfLehninger Principles of Biochemistry, Fifth Edition 2008 W. H. Freeman and Company . 100 75 50 25 200 o 400

Bovine Insulin

Page 19: Biochemistrybonhamchemistry.com/wp-content/uploads/2015/07/Lecture_5.pdfLehninger Principles of Biochemistry, Fifth Edition 2008 W. H. Freeman and Company . 100 75 50 25 200 o 400

Proteins

Page 20: Biochemistrybonhamchemistry.com/wp-content/uploads/2015/07/Lecture_5.pdfLehninger Principles of Biochemistry, Fifth Edition 2008 W. H. Freeman and Company . 100 75 50 25 200 o 400

Proteins

Page 21: Biochemistrybonhamchemistry.com/wp-content/uploads/2015/07/Lecture_5.pdfLehninger Principles of Biochemistry, Fifth Edition 2008 W. H. Freeman and Company . 100 75 50 25 200 o 400

Purification of Proteins

Page 22: Biochemistrybonhamchemistry.com/wp-content/uploads/2015/07/Lecture_5.pdfLehninger Principles of Biochemistry, Fifth Edition 2008 W. H. Freeman and Company . 100 75 50 25 200 o 400
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Page 24: Biochemistrybonhamchemistry.com/wp-content/uploads/2015/07/Lecture_5.pdfLehninger Principles of Biochemistry, Fifth Edition 2008 W. H. Freeman and Company . 100 75 50 25 200 o 400
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Page 27: Biochemistrybonhamchemistry.com/wp-content/uploads/2015/07/Lecture_5.pdfLehninger Principles of Biochemistry, Fifth Edition 2008 W. H. Freeman and Company . 100 75 50 25 200 o 400

Structure of Proteins

Page 28: Biochemistrybonhamchemistry.com/wp-content/uploads/2015/07/Lecture_5.pdfLehninger Principles of Biochemistry, Fifth Edition 2008 W. H. Freeman and Company . 100 75 50 25 200 o 400

Sequence Varies: Ask 23andMe

Page 29: Biochemistrybonhamchemistry.com/wp-content/uploads/2015/07/Lecture_5.pdfLehninger Principles of Biochemistry, Fifth Edition 2008 W. H. Freeman and Company . 100 75 50 25 200 o 400
Page 30: Biochemistrybonhamchemistry.com/wp-content/uploads/2015/07/Lecture_5.pdfLehninger Principles of Biochemistry, Fifth Edition 2008 W. H. Freeman and Company . 100 75 50 25 200 o 400
Page 31: Biochemistrybonhamchemistry.com/wp-content/uploads/2015/07/Lecture_5.pdfLehninger Principles of Biochemistry, Fifth Edition 2008 W. H. Freeman and Company . 100 75 50 25 200 o 400
Page 32: Biochemistrybonhamchemistry.com/wp-content/uploads/2015/07/Lecture_5.pdfLehninger Principles of Biochemistry, Fifth Edition 2008 W. H. Freeman and Company . 100 75 50 25 200 o 400
Page 33: Biochemistrybonhamchemistry.com/wp-content/uploads/2015/07/Lecture_5.pdfLehninger Principles of Biochemistry, Fifth Edition 2008 W. H. Freeman and Company . 100 75 50 25 200 o 400

Structure of Proteins

Page 34: Biochemistrybonhamchemistry.com/wp-content/uploads/2015/07/Lecture_5.pdfLehninger Principles of Biochemistry, Fifth Edition 2008 W. H. Freeman and Company . 100 75 50 25 200 o 400
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Alpha Helices

Page 36: Biochemistrybonhamchemistry.com/wp-content/uploads/2015/07/Lecture_5.pdfLehninger Principles of Biochemistry, Fifth Edition 2008 W. H. Freeman and Company . 100 75 50 25 200 o 400

Beta Strands


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