bio-organic division, bhabha atomic research centre ... · 1 d-glucose based syntheses of -hydroxy...
TRANSCRIPT
1
D-glucose based syntheses of -hydroxy derivatives of L-glutamic acid, L-glutamine, L-proline and a dihydroxy pyrrolidine alkaloid
K. S. Ajish Kumar*, Subrata Chattopadhyay
Bio-organic Division, Bhabha Atomic Research Centre,
Trombay, Mumbai- 400085
Email: [email protected]
Electronic Supplementary Material (ESI) for RSC Advances.This journal is © The Royal Society of Chemistry 2015
2
Content
s.no Title Page no.
1 1H NMR spectrum of 4 6
2 13C NMR spectrum of 4 7
3 1H NMR spectrum of 5 8
4 13C NMR spectrum of 5 9
5 1H NMR spectrum of 6 10
6 13C NMR spectrum of 6 11
7 ESI-MS spectrum of 6 12
8 1H NMR spectrum of 7 13
9 13C NMR spectrum of 7 14
10 1H NMR spectrum of 8 15
11 13C NMR spectrum of 8 16
12 1H NMR spectrum of 9 17
13 13C NMR spectrum of 9 18
14 1H NMR spectrum of 10 19
15 13C NMR spectrum of 10 20
3
16 1H NMR spectrum of 11 21
17 13C NMR spectrum of 11 22
18 1H NMR spectrum of 12 23
19 13C NMR spectrum of 12 24
20 ESI-MS spectrum of 12 25
21 1H NMR spectrum of 13 26
22 13C NMR spectrum of 13 27
22 1H NMR spectrum of 14 28
23 13C NMR spectrum of 14 29
24 ESI-MS spectrum of 14 30
25 1H NMR spectrum of 1a 31
26 13C NMR spectrum of 1a 32
27 ESI-MS spectrum of 1a 33
28 1H NMR spectrum of 15 34
29 13C NMR spectrum of 15 35
30 ESI-MS spectrum of 15 36
31 1H NMR spectrum of 16 37
4
32 13C NMR spectrum of 16 38
33 1H NMR spectrum of 17 39
34 13C NMR spectrum of 17 40
35 ESI-MS spectrum of 17 41
36 1H NMR spectrum of 18 42
37 13C NMR spectrum of 18 43
38 ESI-MS spectrum of 18 44
39 1H NMR spectrum of 19 45
40 13C NMR spectrum of 19 46
41 ESI-MS spectrum of 19 47
42 1H NMR spectrum of 20 48
43 13C NMR spectrum of 20 49
44 1H NMR spectrum of 1b 50
45 13C NMR spectrum of 1b 51
46 ESI-MS spectrum of 1b 52
47 1H NMR spectrum of 21 53
48 13C NMR spectrum of 21 54
5
49 1H NMR spectrum of 22 55
50 13C NMR spectrum of 22 56
51 ESI-MS spectrum of 22 57
52 1H NMR spectrum of 23 58
53 13C NMR spectrum of 23 59
54 ESI-MS spectrum of 23 60
55 1H NMR spectrum of 24 61
56 13C NMR spectrum of 24 62
57 ESI-MS spectrum of 24 63
58 1H NMR spectrum of 1c 64
59 13C NMR spectrum of 1c 65
60 1H NMR spectrum of 2 66
61 13C NMR spectrum of 2 67
62 COSY spectrum of 2 68
63 HMQC spectrum of 2 69
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
Note: The BBI and TXI probe on which 13C NMR (126 MHz) was done, is not optimized for the detection of the 13C nucleus, being an inverse probe, it is optimized for 1H detection, and therefore for weak samples a small hump appears.
33
34
35
36
37
38
Note: The BBI and TXI probe on which 13C NMR (126 MHz) was done, is not optimized for the detection of the 13C nucleus, being an inverse probe, it is optimized for 1H detection, and therefore for weak samples a small hump appears.
39
40
41
42
43
Note: The BBI and TXI probe on which 13C NMR (126 MHz) was done, is not optimized for the detection of the 13C nucleus, being an inverse probe, it is optimized for 1H detection, and therefore for weak samples a small hump appears.
44
45
46
47
48
49
Note: The BBI and TXI probe on which 13C NMR (126 MHz) was done, is not optimized for the detection of the 13C nucleus, being an inverse probe, it is optimized for 1H detection, and therefore for weak samples a small hump appears.
50
51
Note: The BBI and TXI probe on which 13C NMR (126 MHz) was done, is not optimized for the detection of the 13C nucleus, being an inverse probe, it is optimized for 1H detection, and therefore for weak samples a small hump appears.
52
53
54
55
56
57
58
59
60
61
62
Note: The BBI and TXI probe on which 13C NMR (126 MHz) was done, is not optimized for the detection of the 13C nucleus, being an inverse probe, it is optimized for 1H detection, and therefore for weak samples a small hump appears.
63
64
65
Note: The BBI and TXI probe on which 13C NMR (126 MHz) was done, is not optimized for the detection of the 13C nucleus, being an inverse probe, it is optimized for 1H detection, and therefore for weak samples a small hump appears.
66
67
Note: The BBI and TXI probe on which 13C NMR (126 MHz) was done, is not optimized for the detection of the 13C nucleus, being an inverse probe, it is optimized for 1H detection, and therefore for weak samples a small hump appears.
68
69