Bio 449 Lecture 20 - Cardiovascular Physiology III Oct. 15, 2010

Heart (cont’d)Cardiac output (conclusion)Control of cardiac outputBlood flowVessel size, blood velocity and pressureControl of blood distribution Poiseuille's LawLocal vs. systemic effects of vasoconstrictionRegulation of arteriolar diameter Capillary function Lymphatic system

Terms to KnowStarling's Law of the Heart Poiseuille's LawViscosity Total peripheral resistance (TPR)Mean arterial pressure (MAP)Central venous pressure (CVP) VasodilationVasoconstriction Active hyperemiaNitric oxide UltrafiltrateLymphLymphatic systemLymphatic vesselsEdema

ReadingsLectures 18-20: Chapter 14 & 15Lectures 21-22: Chapter 17

Control of Cardiac Output

Effects of sympathetic activity on HR

Fig. 14-16

Effects of parasympathetic activity on HR

Fig. 14-16

Starling’s Law

Fig. 14-28

Blood Flow

Vessel size, blood velocity and pressure

BP levels throughout circulatory system

Fig. 15-5

BP levels throughout circulatory system

Fig. 15-5

Control of blood distribution

Fig. 15-14

Poiseuille’s Law

Local vs. systemic effects of vasoconstriction

Regulation of arteriolar diameter

Capillary function

Movement across capillary walls

Similar to Fig. 15-17

Lymphatic system

Lymph capillary

Overlappingendothelial cellsInterstitial

fluid

Lymph

Uptake of lymph

Arteriole

Netabsorption

Lymphvessels

Netfiltration

Venule

Fig. 15-19

Lymphatic system

Fig. 15-19

Spleen

Lymph nodes

Thymus

Blind-end lymphcapillaries

Lymph fluid empties into superior vena cava.