bio 178 lecture 22
DESCRIPTION
Bio 178 Lecture 22. Meiosis. http://homepage1.nifty.com/scilla/sonota/ityou/ityou.html. Reading. Chapter 12. ?. Quiz Material. Questions on P 240 Chapter 12 Quizzes on Text Website (www.mhhe.com/raven7). Outline. Sexual Reproduction The Sexual Life Cycle Meiosis. - PowerPoint PPT PresentationTRANSCRIPT
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Bio 178 Lecture 22Meiosis
http://homepage1.nifty.com/scilla/sonota/ityou/ityou.html
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Reading
• Chapter 12
Quiz Material
• Questions on P 240
• Chapter 12 Quizzes on Text Website (www.mhhe.com/raven7)
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Outline
• Sexual Reproduction The Sexual Life Cycle
Meiosis
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The Sexual Life cycle• Alternation of Generations
All sexual life cycles alternate between a haploid and diploid state. In some organisms the diploid stage is dominant and in others the haploid stage is dominant.
This is a consequence of mitosis and meiosis:
• MitosisMaintains chromosome number.
• Meiosis
Halves chromosome number.
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The 3 Types of Sexual Life Cycle
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Unique Features of Meiosis
McGraw-Hill Video
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Genetic Variation in the Sexual Life Cycle• Maternal and Paternal ChromosomesIf there was no exchange of genetic material between the homologues each gamete would receive an entire homologue that is either maternal or paternal.
• The Process of Crossing OverPurposeGenetic Variation
SynapsisPairing of chromosomes along their length (after DNA replication).Homologues attached to nuclear envelope.
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Synaptonemal Complex
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Synaptonemal Complex
http://www.ucl.ac.uk/~ucbhjow/bmsi/synapto.html
(Enzymes)
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Spermatocyte Synaptonemal Complex
http://7e.devbio.com/article.php?ch=19&id=188
Green = SCP 1
Blue = DNA
Red/Yellow = Centromere
Top = Normal
Bottom = SCP 3 deficient
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Genetic Variation in the Sexual Life CycleCrossing Over• DNA is exchanged between the non-sister chromatids at the chiasmata.
• Recombination nodules break and rejoin homologous chromatids.
http://www.blc.arizona.edu/courses/181summer/10.html
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Post Crossing Over
• Synaptonemal complex breaks down.
• Homologues are now joined only by common centromeres and chiasmata.
• Homologues released from nuclear envelope.
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Comparison of Meiosis and Mitosis
McGraw-Hill Video
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Meiosis• Cell Divisions
2 divisions after the chromosomes have replicated:
Meiosis I
Separation of homologous chromosomes.
Meiosis II
Separation of sister chromatids.
• Ploidy
Diploid Haploid
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Meiosis I• Prophase IChromosomes finish condensing.
Synapsis and crossing over occur.
Centrioles (animal cells) move to opposite poles and spindle fibers form between them.
Nuclear envelope breaks down.
Chiasmata move to the ends of the chromosomes ( terminal chiasmata).
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Prophase I
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Meiosis I (Cntd.)• Metaphase I
Homologous chromosomes align on the metaphase plate, attached to the kinetochore microtubules. These are attached only to the outward facing kinetochores.
Independent assortment - The homolgue orientation is random.
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Metaphase I
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Independent Assortment
McGraw-Hill Video
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Meiosis I (Cntd.)• Anaphase IHomologues separate and are pulled to opposite poles.
• Telophase I
Homologues reach opposite poles.
Nuclear envelopes may form.
• Cytokinesis
May occur.
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Anaphase I
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Telophase I
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Meiosis II
• Prophase II
There may be a brief interphase, but NO DNA SYNTHESIS occurs.
Centrioles move to opposite poles and spindle fibers form.
If the nuclear envelope reformed it breaks down.
• Metaphase IIChromosomes align at the metaphase plate. Kinetochore microtubules are attached to both sides of the centromere.
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Prophase II
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Metaphase II
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Meiosis II (Cntd.)• Anaphase II
Sister chromatids separate and are pulled apart ( chromosomes).
• Telophase II
Chromosomes reach opposite poles.
Nuclear envelopes form.
• Cytokinesis
Results in 4 daughter cells.
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Anaphase II
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Telophase II
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Biodidac. http://biodidac.bio.uottawa.ca/thumbnails/filedet.htm?File_name=19-7D&File_type=GIF
?
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Sources of Genetic Variation in Meiosis
• Crossing over
• Independent assortment