Benefiting government, industry and the public through innovative science and technology

SouthwestResearch Institute

Steve Wellinghoff, Ph.DInstitute Scientist, Chemistry and Chemical Engineering Division

San Antonio, Texas, (210) 522-3084, swellinghoff@swri.org

SwRI® Today

Over 3,200 employees Revenue in 2012 exceeded

$584 million Over 1,200 acres / 4.86 km2 facility

in San Antonio, Texas 2.2 million ft2 / 204,400 m2 of

laboratories & offices Over 1000 patents Multiple US and foreign Locations 37 R&D 100 awards

www.swri.org

Operational Characteristics

Not for profit 501C3 Revenue from contracts Applied RDT&E services Physical sciences & engineering Broad technological base Capital intensive operation Internal research program

– $ 7.4 million in FY 2012– 84 projects

S O U T H W E S T R E S E A R C H I N S T I T U T E

SwRI® Organization Chart

Fuels& Lubricants

Research

Quality

OperationsLegal

Human Resources

Board of Directors

AppliedPower

SpaceScience

& Engineering

MechanicalEngineering

SignalExploitation

& Geolocation

Engine,Emissions& VehicleResearch

Automation & Data

Systems

Chemistry & ChemicalEngineering

AppliedPhysics

BusinessFacilities/Services

Treasurer

President

CFO and SeniorVice President

ExecutiveVice President

U.S. NuclearRegulatory

Commission

Geosciences& Engineering

CNWRA

AerospaceElectronics

& InformationTechnology

IR&D Program Objectives•Preliminary Data•IP position•Collaborations• Intramural

•Extramural

Reviewed by ACR•Regular•Quick Look•Disruptive

Reviewed by SpecialCommittee•Presidential•Connect Program SwRI-UTSA

Biomedical Research

Manufacturing Extension Partnership – TMAC Program

60 Centers like TMAC nationwide

5

SwRI Partnership Benefits• Broad technical expertise to compliment a small business skill set.• Interest in developing technology not competing on commercialization.• Established reputation of delivering on project deliverables.• Flexible approach to intellectual property.• Establish business operations to handle government contracting.

SwRI’s Interests • Participation on cutting edge technologies.• Developing relationships with entrepreneurial community• Developing relationships with government program managers• Contract R&D dollars

Partnering with SwRI on SBIR/STTR Phase 1, Phase 2 Programs

Recent SBIR/ STTR Awards with SwRI PartnerPhase 1• Plasma Immersion Ion Processing (PIIP) of Organic/ Inorganic based layered Anti-Reflection Coatings ( INTERMaterials LLC)- Utilize PIIP to deposit with SiO2, TiO2 and Al2O3 as the organic/ inorganic hybrids for the optical coating materials onto curved plastic parts.• Graded-Composition Refractory Coatings for Protection of Cu-Rails for Electromagnetic Launchers (Engineered Coatings Inc.) - Use Plasma Enhanced Magnetron Sputtering (PEMS) to deposit thick, erosion, and wear-resistant coatings on Cu.• Non-Toxic, Corrosion-Resistant Amorphous Coatings for Protection of Steel Tailhook Components (Engineered Coatings Inc.) - Deposition trials to fabricate amorphous Al-Co-Ce coatings using IBAD with e-beam evaporation.• Diamond-Like Carbon Coatings for Low-Friction Ducting (Aspen Systems) – Apply Diamond like carbon coating to the inside of air ducts.• Preparation of Mo-Si-B Particles (Aspen Systems Inc.)• Impact Indicator Paints (Luna Innovations)• Smart Coatings for Impact Indication (Luna Innovations)• Extended Pot Life Marine Coatings (Luna Innovations)• Multifunctional Self-Healing Coatings (Luna Innovations)• Self-Healing Adhesives and Composites (Luna Innovations)• Impact Indicating Paint (Luna Innovations)

Phase 2• Thin-Film, Ceramic Thermocouple Sensors Fabricated by Enhanced Plasma Deposition and Shadow-Mask Patterning (Engineered Coatings Inc) – Develop a nitride based thermocouple for the hot section of aircraft engines.• Modeling of Microwave –Infrared Double Resonance Spectroscopy for Detection of Explosives and Hazardous Chemicals (Kestrel Corporation) – Density Functional Theory and Hartree-Fock computational modeling of identified species with specific excitation wavelengths.• Advanced Oxygen Evolution Catalysts for PEM Electrolyzers (Lynntech Inc.) - Production of nano-platelet binary catalysts.• Improved Performance, More Producible Long Wave IR Integrated Dewar Assemblies (N-Science Corp.) – development of coatings for cryogenic applications.• Intelligent Processing using Vartram ( Eltron) – Polymer processing optimization.• Intelligent Coatings for Self Healing (Luna Innovations }• Impact Indicator Paints (Luna Innovations)• Damage Indicating Paints (Luna Innovations)• Blood –Brain Barrier Bypass Technology (Impel NeuroPharma)

Recent SBIR/ STTR Awards with SwRI Partner

SwRI Projects with Small Manufacturers

SwRI501C3

New Small Business

Small BusinessUniversity

Spinout

LicenseAgreement

SBIR/STTR Phase 1/Phase 2sFor Small Pilot Scale Process

IP Terms

IR&D/Government Funding of Related Onsite Scaled Pilot Production Processes with

Appropriate HAZOP/ISO Procedures

Private Funding

Private Funding

Demonstration , Multiple Unit Operation,Large Pilot Facility at SwRI

SwRI Administered TMAC Funding

Onsite/RemoteMonitoring of Process

By Small BusinessCash Flow to Small BusinessFrom Sale of Side Products

Attract More Investment

Large Scale Production Of Final Product Remote

From SwRI

Drug Development with Small Business

SwRI501C3 Rapamycin

Holdings, Inc

University of Texas Health

Science Center SA/Barshop

InstituteLicenseAgreement

US Government FundingFor Anti-aging Drug

IR&D/Government Funding forMicro/Nanoencapsulation

of Drugs

Texas Research & Technology Foundation, TRTF

Texas Technology DevelopmentCenter, T3DC

Phase 1 Clinical Trials

Complete Clinical Trials for Potential Product Deployment

Pre-clinical Work

Attract More Investment

STTMContracting Agreement

www.uthscsa.edu/hscnews/singleformat2.asp?newID=4358

www.uthscsa.edu/hscnews/pdf/rapamycin_quotes.pdf