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BATCH & CONTINUOUS MIXING PROCESS TECHNOLOGIES FOR TOMORROW

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Page 1: BATCH & CONTINUOUS MIXING - HolimexIn this brochure, we have divided the mixers according to their suitability for batch and continuous applications, ranging from low shear (gentle

BATCH & CONT INUOUS MIX ING

P R O C E S S T E C H N O L O G I E S F O R T O M O R R O W

Page 2: BATCH & CONTINUOUS MIXING - HolimexIn this brochure, we have divided the mixers according to their suitability for batch and continuous applications, ranging from low shear (gentle

Agglomeration

MixingDrying

P R O C E S S T E C H N O L O G I E S F O R T O M O R R O W

ABOUT HOSOKAWA MICRON B.V.

Hosokawa Micron B.V. is specialist in the design, manufacture and supply of powder

processing systems and equipment for the mechanical and thermal processing of dry and

wet powders. Located in Doetinchem in the Netherlands, Hosokawa Micron B.V. is expert

in mixing, drying and agglomeration.

Hosokawa Micron B.V. was established in 1987 as a result of a merger between Nautamix

in Haarlem (founded in 1923), Machinefabriek Vrieco in Zelhem (founded in 1939) and

ISEM in Doetinchem (founded in 1928). In 2000 Schugi in Lelystad (founded in 1954) was

merged into the company. Today, Hosokawa Micron B.V is one of the main companies

within the Hosokawa Group.

MISSION STATEMENT

Hosokawa Micron B.V. is a leader in offering technological know-how and solutions in the

field of mixing, drying and agglomeration. By our professionalism, service orientation and

dedication we help clients to achieve their goals, or even exceed them. In doing so we

achieve long-term relationships with both clients and suppliers as well as an attractive

return for our shareholders.

We offer a challenging and motivating work environment for our employees and want to

contribute to a sustainable society.

2

Page 3: BATCH & CONTINUOUS MIXING - HolimexIn this brochure, we have divided the mixers according to their suitability for batch and continuous applications, ranging from low shear (gentle

CONTENTS

ABOUT HOSOKAWA MICRON B.V. 2

MIXING TECHNOLOGIES 4

MIXER SELECTION 6

BATCH MIXING 8

CONTINUOUS MIXING 18

LAB EQUIPMENT 24

ANCILLARIES / OPTIONS 25

SYSTEM SOLUTIONS 26

PROCESS AUTOMATION 28

APPLICATIONS 30

TESTING & TOLLING 38

SERVICE & SUPPORT 40

CONTACT 42

FoodPharmaceuticals

Minerals & metalsChemicals

3

Page 4: BATCH & CONTINUOUS MIXING - HolimexIn this brochure, we have divided the mixers according to their suitability for batch and continuous applications, ranging from low shear (gentle

M I X I N G T E C H N O L O G I E S

SELECT ING THE R IGHT MIXER

The first step to selecting the right equipment is a thorough analysis of the powders (and

liquids) you wish to process. This analysis will give you a clear understanding of all of the

medium’s characteristics, which need to be taken into account during processing.

Some powders need a gentle mixing, while others need more mixing energy to create a

quality mixture. Design parameters, for example, cross contamination between batches and

operating pressures will also influence the final design of the mixer.

In this brochure, we have divided the mixers according to their suitability for batch and

continuous applications, ranging from low shear (gentle mixing) to high shear (intensive

mixing).

Hosokawa Micron B.V. is certified according to the international standard NEN-EN-ISO 3834-2

for welding. The ISO 3834 quality standard applies to all activities in the field of welding and

covers the entire welding organisation.

State-of-the-art powder processing solutions

Hosokawa Micron B.V. specialises in the design and manufacture of innovative technologies

for powder processing in a number of industries, including food, pharma, chemicals and

minerals & metals. By focusing on these over the years, we have developed in-depth and

unparalleled experience and know-how that we enjoy sharing with our customers.

MIXING TECHNOLOGIES AT HOSOKAWA MICRON

Mixing is one of the oldest unit operations in powder processing and we have dedicated over

90 years to developing experience and know-how in this field. We have translated this wealth

of knowledge into different technologies such as the Nauta® mixer, Vitomix, Cyclomix and

Flexomix, which are now strong brands and fundamental technologies in a great number of

industries and applications.

Hosokawa Micron provides a powerful combination of complete powder processing solutions.

These encompass innovatively-designed and expertly-engineered mixing, drying, agglomeration,

milling and containment technologies, as well as ancillary equipment, assembly, commissioning,

on-site training and process optimisation.

Our R&D centre in Doetinchem, the Netherlands, provides valuable test facilities for customers

looking to perform mixing tests on a laboratory, pilot and production scale. These are unique

and enable us to offer the perfect mix of technology and powder processing knowledge all

under one roof.

CHALLENGE US TO SOLVE YOUR MIXING PROBLEMS!

4

Page 5: BATCH & CONTINUOUS MIXING - HolimexIn this brochure, we have divided the mixers according to their suitability for batch and continuous applications, ranging from low shear (gentle

M I X I N G T E C H N O L O G I E S

CHALLENGE US TO SOLVE YOUR MIXING PROBLEMS!

Bulk pharmaceuticals

Polymers

Catalysts

Food ingredientsFlavours

Injectables

Metal powders

Agrochemicals

Ceramics

Mineral fillersPigments

5

Page 6: BATCH & CONTINUOUS MIXING - HolimexIn this brochure, we have divided the mixers according to their suitability for batch and continuous applications, ranging from low shear (gentle

Mix

er se

lectio

nHigh shear/impact mixer

The Cyclomix is a high shear intensive mixer

specially designed for fine cohesive powders,

slurries and liquids.

Ribbon screw mixer

The Vitomix is a low and mid-shear mixer,

capable of ultra-quick cycle times, with up

to 8 times more transport volume than

conventional screw cone mixers.

Conical paddle mixer

The conical paddle mixer is a low and

mid-shear mixer for mixing powders,

granules and solids with liquids. It is a

multi-purpose mixer for processes where

high accuracy, speed and limited product

distortion are important.

High shear

Mid shear

Low shear

Conical screw mixer

The Nauta® conical screw mixer is a

low intensity mixer specially

designed for segregative, free-

flowing materials and pastes.

The Nauta mixer is also suitable for

cohesive products when used in

combination with an intensifier.

BATCH

6

Page 7: BATCH & CONTINUOUS MIXING - HolimexIn this brochure, we have divided the mixers according to their suitability for batch and continuous applications, ranging from low shear (gentle

High speed paddle mixer

The high speed paddle mixer has been

developed for fine and cohesive powder

applications. The mixing intensity can be

tailored to the specific application by adjusting

paddle pitch and shaft speed.

High shear

CONTINUOUS

Mid shear

High impact mixer

The Schugi Flexomix is a high intensity

continuous mixer, developed to perfect

the mixing of free-flowing and cohesive

powders with liquids.

Modular paddle mixer

The Modulomix is a continuous modular

mixer based on the proven Cyclomix batch

mixing technology. It can be used for low,

medium or high shear applications and it

can be integrated into a PAT (Process

Analytical Technology) environment.

7

Page 8: BATCH & CONTINUOUS MIXING - HolimexIn this brochure, we have divided the mixers according to their suitability for batch and continuous applications, ranging from low shear (gentle

Batch

mix

ing

The Nauta® mixer is a conical screw mixer specially designed for segregative,

free-flowing powders and pastes. It is a pioneer in mixing technology and

famous for its low-intensity mixing. The first conical Nauta mixer was

developed by Mr. J.E. Nauta in 1946. In 1982 the Nautamix company was

acquired by Hosokawa Micron.

Today, the Nauta batch mixer is synonymous worldwide with high accuracy

and gentle mixing of large volumes of up to 100 000 litres. As the innovators,

Hosokawa Micron B.V. continue to dedicate research and development into

this leading mixing technology and sold more than 15 000 conical mixers in

a wide variety of applications.

Typical applications

Nauta mixers are suitable for a wide range of processes and applications:

• Gentle mixing of free flowing, fragile and/or segregative powders

• Mixing of pastes and slurries

• Liquid addition to powders and pastes

• Temperature treatment, cooling/heating

• Reactor vessel in pressurised conditions/vacuums

• Live hopper for sticky or segregative products

Working principle

The Nauta conical screw mixer is a convective mixer with high mixing

efficiency. It is gentle and guarantees the highest level of mixing accuracy

without product distortion. The screw has an average speed of 70 rpm whilst

the arm rotates at 1 to 2 rpm. The tip speed of the screw can fluctuate

between 0.5 and 2 m/s, making it suitable for all ATEX zones.

The rotating cantilevered mixing screw conveys the product from the bottom

of the vessel to the product surface. The mixing screw is suspended from an

orbital arm, which rotates the mixing screw along the conical inner vessel

wall causing convective mixing of particles and shear.

When recirculated by gravity in a conical vessel, the speed of particles in the

downward mass flow increases as the vessel diameter decreases.

These simultaneous actions result in fast and intensive mixing with low

power consumption and high mixing accuracy.

Conical screw mixer

8

Page 9: BATCH & CONTINUOUS MIXING - HolimexIn this brochure, we have divided the mixers according to their suitability for batch and continuous applications, ranging from low shear (gentle

Mixer configuration

The Nauta mixer is available in a wide variety of configurations for a broad range of process and application requirements.

We have included some of the most common configurations below.

Flat cover• For normal atmospheric conditions• No special cleaning requirements• Bolted to mixer vessel

Single screw configuration• Standard execution• Variety of designs

Cantilevered (no support)• Suitable for mixers up to 20 000 litres• For heat sensitive and fragile products• Full discharge / bottom outlet• For sanitary applications and easy cleaning

Semi-domed cover• Up to 0.1 bar positive/negative pressure• Suitable for dry and wet cleaning• Integrated with vessel and support bridge

Double screw configuration• Reduced mixing times• Improved heat transfer

Radial bottom locator• Suitable for mixers up to 12 000 litres• For heavy duty applications• In combination with side outlet

Domed cover• Full vacuum and up to 10 bar• Sanitary design• Integrated with vessel

Intensifier• Provides additional mixing energy• Can be combined with liquid spray devices

Ball head bearing• Suitable for mixers up to 100 000 litres• Heavy-duty and heat-sensitive applications• In combination with side outlet

Vessel/cover design

Mixing elements

Screw support

9

Page 10: BATCH & CONTINUOUS MIXING - HolimexIn this brochure, we have divided the mixers according to their suitability for batch and continuous applications, ranging from low shear (gentle

Cleanability

When it comes to cleaning mixing equipment, we ask ourselves what the best

way is of combining our smart designs with your quality manufacturing processes.

Minimising downtime is the ultimate goal, but it would be naïve to think we

could avoid time-consuming cleaning processes for mixing operations all

together.

The determining factor when choosing a particular type of cleaning is your

application. There are many aspects to consider, and plenty of philosophies about

cleaning, but one of the most difficult questions to answer is when something is

truly clean, and how to control the results.

To this end, we offer three categories of cleaning:

• Wet cleaning

• Dry cleaning

• Sterilisation

We offer a range of fixed or removable cleaning systems for automatic (wet)

cleaning using gas and liquid cleaners. These include customised CIP and drying

skids. We also have large access doors, platforms and manual spray lances for

(wet) cleaning your systems manually, ensuring good and safe accessibility to the

areas that need to be cleaned.

This is an integral part of the design phase and our specialists are here to help

you incorporate this into your mixer design right from the start. Our expert

advice on cleanability in combination with sustainability will help you save costs,

protect the environment and achieve the best possible results.

Batch

mix

ing

Heating/cooling

A jacketed vessel can be supplied to

heat or cool the product. Dependant on

temperature, pressure and medium,

one or several jacket segments are

welded to the vessel wall fully in

compliance with the requirements of

coding authorities. The jacket is

designed to force the medium around

the vessel achieving maximum

temperature transfer effect.

10

Page 11: BATCH & CONTINUOUS MIXING - HolimexIn this brochure, we have divided the mixers according to their suitability for batch and continuous applications, ranging from low shear (gentle

VersatileEfficient

World renownedProven technology

Flexible

Accurate

Gentle mixing

Size [l]

Vessel diameter [mm]

Vessel height [mm]

Height incl. motor [mm]

Typical motor power [kW]

500

1450

1750

2250

2.2

1000

1800

2250

2900

5.5

2000

2100

2800

3500

7.5

5000

2850

3800

4700

15

20 000

4400

6000

7300

37

10 000

3550

5000

6200

22

50 000

5700

8250

9650

55

100 000

7000

9000

10 300

90

Models & specifications

The Nauta mixer is available in many sizes. A few sizes with their typical characteristics are described below. Please note that these values

are indicative only. Detailed information is available on request.

Key features

Proven technology

Hosokawa offers you their experience of 15 000 successful references since the development of the first

conical Nauta mixer in 1946. Since then, numerous improvements have been made. Thanks to our

continuous dedication to product development, the Nauta mixer is acknowledged globally as a

state-of-the-art mixing technology for the powder processing industry.

Perfect quality

It can be used for low intensity with a minimum of energy input, and produces minimal product

distortion, perfect quality and accuracy for a wide range of powders, slurries and liquids. The Nauta

mixer is very flexible and delivers constant mixing quality with mixer volumes of 15% all the way up

to 100%.

Versatile

The Nauta mixer can be configured to suit applications in the chemical, mineral, metal, food,

pharmaceutical and nuclear industries. It can be designed to provide effective heating, cooling, drying,

mixing and moistening in one complete process and can be adapted for use in hazardous areas

(ATEX approved).

11

Page 12: BATCH & CONTINUOUS MIXING - HolimexIn this brochure, we have divided the mixers according to their suitability for batch and continuous applications, ranging from low shear (gentle

Batch

mix

ing

The conical paddle mixer is the newest generation of Hosokawa

powder mixers, developed for low and medium shear batch mixing.

It has been designed for mixing powders, granules and solids with

liquids. The conical paddle mixer is a multi-purpose mixer for processes

where high accuracy and fast mixing with limited product distortion

are important.

Typical applications

The conical paddle mixer is suitable for a wide variety of process

applications, including:

• Mixing of fragile powders and ´instant´ agglomerates

• Mixing of powders with liquids

• Sterilisation and pasteurisation of product batches

• Temperature processing of powders and liquids

• (Vacuum) drying at low temperature with liquid recovery

Working principle

The mixing vessel is conical shaped and equipped with a central

paddle rotor. When it rotates, the rotor creates a combination of

vertical and axial motion in the vessel. The paddles guide the product

gently to the surface of the batch, where it is dispersed and the

gravitational pull at the centre of the mixer forces the product back

down to create continuous motion throughout the mixing cycle, even

at low speed.

The mixing process can be optimised by controlling the mixing energy,

which can be achieved by adjusting the rotational speed. The conical

paddle mixer has a typical rotor speed of between 1 and 10 m/s.

Conical paddle mixer

12

Page 13: BATCH & CONTINUOUS MIXING - HolimexIn this brochure, we have divided the mixers according to their suitability for batch and continuous applications, ranging from low shear (gentle

Multi processing

Temperature controlHeavy duty

Low & mid shear

Key features

Design

The heavy duty and smart design, with central rotor and external drive, makes the conical

paddle mixer suitable for multiple processes. These can vary from high accuracy to heavy

duty mixing, chemical reactions, and vacuum drying, to mixing processes which demand

cleaning/sterilisation. Its compact design with conical shaped vessel and large bottom

outlet, guarantee fast and full discharge. The typical yield for free-flowing powders is

99.99%.

Fragile products

The gentle mixing action combined with short mixing times, makes the conical paddle

mixer suitable for fragile products with minimum product distortion.

Temperature control

The action of the mixing rotor keeps the product in constant motion, and in frequent

contact with the vessel wall. This optimises the heat transfer between vessel and product,

making the conical paddle mixer an ideal mixer for processes where temperature control

and energy efficiency are key.

Size [l]

Vessel diameter [mm]

Outlet diameter [mm]

Height incl. motor and ball valve [mm]

Typical motor power [kW]

50

500

80

1250

0.25 - 1.1

500

1000

150

2500

2.2 - 11

1000

1250

250

3200

4 - 15

2000

1550

250

4000

7.5 - 30

Models & specifications

The conical paddle mixer is available in several sizes. A few sizes with their typical characteristics are described below. Please note that these

values are indicative only. Detailed information is available on request.

On request

> 15 0003000 - 15 000

1750 - 3000

300 - 500

4500 - 7250

On request

13

Page 14: BATCH & CONTINUOUS MIXING - HolimexIn this brochure, we have divided the mixers according to their suitability for batch and continuous applications, ranging from low shear (gentle

The Vitomix ribbon screw mixer is a multi-functional mixer that

combines gentle and mid shear mixing in one machine. Compared to

conventional conical mixers, the Vitomix has a compact design and a

wide operating range. With up to eight times more transport volume,

it is a very energy-efficient mixer with low operational costs and short

mixing times.

Typical applications

The Vitomix is suitable for a wide variety of process applications,

including:

• Fast mixing of powders, pastes and slurries

• Addition of liquids or fats without the use of lump breakers

• Combining gentle mixing with mid shear mixing in one machine

• Granulating

• Flavouring

• Colouring

• Heating / cooling

Working principle

The Vitomix is equipped with two conical ribbon screws mounted on

an orbital arm that transports the product from the bottom of the

vessel to the surface. The material flows downwards through the cen-

tre of the vessel by gravity whilst the high rotational speed of the

agitator ensures mid-shear mixing in very short batch times.

The design of the two ribbon screws enables the transportation of

large quantities of product to the surface of the batch where it is

fluidised with a high degree of product refreshment. This technique

makes the Vitomix ideal when you want to add liquids to the

powder(s) you are mixing. The Vitomix has a variable tip speed of

between 0.4 and 6 m/s.

Ribbon screw mixerB

atch

mix

ing

14

Page 15: BATCH & CONTINUOUS MIXING - HolimexIn this brochure, we have divided the mixers according to their suitability for batch and continuous applications, ranging from low shear (gentle

Key features

Mixing time

The special design of the Vitomix results in a substantial improvement in mixing efficiency and a

much more efficient and faster mixing process even at lower speeds. The Vitomix is up to 8 times

faster than conventional mixers.

Adding liquids without creating lumps

The design of the two conical screws creates a fluidised bed in the upper part of the mixer cone

that is perfect for adding liquids such as fats, coating agents, flavours and fragrances, without

creating lumps. This eliminates the need for lump breakers.

Multi-processor

The Vitomix can combine its low and mid shear mixing with multiple unit operations, for example

drying, heating, cooling, liquid addition, de-aeration and coating, in one machine.

Full discharge

The combination of a conical vessel, the special design of the mixing screw, and the large bottom

outlet guarantees fast and full discharge, without the risk of segregation. Typical yield for

free-flowing powders is 99.99%.

Models & specifications

The Vitomix is available in several sizes. A few sizes with their typical characteristics are described below. Please note that these values are

indicative only. Detailed information is available on request.

Short cycle times

Energy efficientMulti-processorFast & gentle

Full discharge

State-of-the-art technology

Size [l]

Vessel diameter [mm]

Vessel height [mm]

Height incl. motor [mm]

Typical motor power [kW]

500

1230

1260

1590

1.1 - 11

1000

1530

1690

2270

5.5 - 18.5

2000

1900

1890

2480

5.5 - 30

3000

2160

2430

3380

7.5 - 45

5000

2550

2870

3860

15 - 75

15

Page 16: BATCH & CONTINUOUS MIXING - HolimexIn this brochure, we have divided the mixers according to their suitability for batch and continuous applications, ranging from low shear (gentle

Batch

mix

ing

The Cyclomix is a revolutionary high speed paddle mixer designed for

intensive mixing of cohesive powders. The mixing principle is based on a

combination of high shear and high impact forces which can be used for

different applications. The Cyclomix combines different processes in one

single machine.

Typical applications

The Cyclomix is suitable for a wide variety of process applications,

including:

• Intensive mixing of cohesive powders, slurries and liquids

• Coating of powders with powders or liquids

• Agglomeration by temperature or moisture addition

• Dispersion of pigments

• (Vacuum) drying at low temperature with liquid recovery

• Spheronisation of particles

• Grinding or de-agglomeration

• Heating or cooling

Working principle

The mixing vessel is conical shaped and has a central rotor which rotates

at a tip speed of 3 up to 30 m/s. The speed of the rotor creates centrifugal

forces that push the product to the vessel wall where the shape of the

vessel causes an upward movement.

The domed cover guides the product towards

the centre of the mixer and at the top, an impact

blade efficiently disperses cohesive powders and

liquids and controls particle size. The patented mixing

mechanism of the Cyclomix ensures a homogeneous

end product and an ultra-short batch time.

High shear impact mixer

16

Page 17: BATCH & CONTINUOUS MIXING - HolimexIn this brochure, we have divided the mixers according to their suitability for batch and continuous applications, ranging from low shear (gentle

Key features

Combined high shear and impact mixing

The unique combination of high shear and impact forces are used for mixing cohesive and/or

sticky products.

Excellent temperature control

The design of the Cyclomix ensures accurate control of the product temperature. It offers an

intensive mixing process with effective heat transfer between the heat-controlled jacketed wall

and the product, enabling effective cooling and heating.

Seals above product zone

The rotor in the Cyclomix is driven from the top, and therefore has no seals or bearings that come

in direct contact with the product.

Easy discharge

The Cyclomix has a conical shaped vessel with a central outlet at the bottom that guarantees easy

discharge and optimal yield.

Multi-processor

Mixing & Agglomeration

High impactHigh shearTemperature control

Models & specifications

The Cyclomix is available in several sizes. A few sizes with their typical characteristics are described below. Please note that these values are

indicative only. Detailed information is available on request.

Size [l]

Vessel diameter [mm]

Outlet diameter [mm]

Height incl. motor [mm]

Typical motor power [kW]

5

300

80

280

0.75 - 5.5

15

530

100

670

1.5 - 15

50

650

150

713

4 - 30

150

950

200

823

11 - 75

2000

2250

400

3125

65 - 240

500

1400

300

1178

30 - 110

1000

1840

350

2657

45 - 160

17

Page 18: BATCH & CONTINUOUS MIXING - HolimexIn this brochure, we have divided the mixers according to their suitability for batch and continuous applications, ranging from low shear (gentle

Co

ntin

uo

us

mix

ingThe Schugi Flexomix is a unique vertical continuous mixer and agglomerator,

developed to achieve a highly homogeneous mixture of powders and liquids. It is

unlike any other continuous mixer with its vertical cylindrical chamber and vertical

rotating shaft. Its high rotational speed and turbulent mixing keep the mixer

chamber clean; it provides accurate dosing of both liquid and solid components

and is suitable for even the stickiest of media.

The Flexomix mixes powders with powders or powders with liquids excellently and

homogeneously, even if the products are sticky. This also makes it highly suitable

for wet agglomeration.

Typical applications

The Flexomix is suitable for a wide variety of process applications, including:

• Modification of starch

• Agglomeration of veterinary antibiotics

• Hydration of phosphates

• Agglomeration of detergents

• Finishing of filter cake

• Instantising of drinking chocolate

• Adding crosslinking agents to super absorbent polymers (SAP)

• Humidifying various products before extrusion

• Agglomerating pesticide formulae

Working principle

The Schugi Flexomix uses highly controlled mixing conditions to achieve optimal

product characteristics and maximum efficiency. It is unlike any existing equipment

and consists of a vertical cylindrical chamber enclosing a vertical rotating shaft.

Several pitch adjustable knives are secured to the shaft, which rotate at high

speed resulting in highly turbulent air flow.

Any number of powders can be fed into the unit through top inlet(s) whereby

agitation causes a spiral flow and high collision rates in the suspension. Liquids of

varying viscosity and steam can be added using atomizing nozzles mounted to the

upper part of the chamber just above the upper mixing blades.

Power requirements are low as there is only ever a small amount of product in the

mixing chamber at any one time, and the unit can be fully disassembled for major

cleaning or product changes in just 2 minutes.

High impact mixer

18

Page 19: BATCH & CONTINUOUS MIXING - HolimexIn this brochure, we have divided the mixers according to their suitability for batch and continuous applications, ranging from low shear (gentle

Key features

Gentle processing

The Flexomix requires minimal operator intervention and can process dry powders in

combination with liquids into uniform and free-flowing, non-compacted, granular products

using atomising nozzles. The gentle processing of the Flexomix produces dust-free instant

products which dissolve quickly.

Simple construction

The Schugi Flexomix has a central rotating shaft with adjustable blades that is located in a

vertical, flexible chamber. This has significant advantages when it comes to maintenance and

cleaning. It has variable shaft speeds from 1000 to 3500 rpm and a set of pneumatically

operated, external rollers that flex the mixing chamber continuously, maintaining the mixing

conditions and keeping it clear of build-up.

Total solution

Hosokawa Micron B.V. designs and manufactures complete systems. In the case of the

Schugi Flexomix for example, they can include final fluid bed dryers for use in the production

of agglomerates. For other combinations, we can recommend taking advantage of our

testing and tolling facilities and our wealth of operational data from existing Flexomix

systems all over the world.

High capacity

EfficientMulti-purpose

Mixing & Agglomerating

FlexibleHigh shear

Accurate

EfficientModel [-]

Dimensions (L x W) [mm]

Height incl. motor [mm]

Capacity (bulk density of 0.5 kg/l) [kg/h]

Typical motor power [kW]

Models & specifications

The Flexomix is available in several models. Their typical characteristics are described below. Please note that these values are indicative

only. Detailed information is available on request.

FXD-100

520 x 650

1265

50 - 150

3

FXD-160

702 x 620

1500

250 - 1000

7.5

FXD-220

976 x 880

1967

800 - 2500

7.5 - 10

FXD-250

976 x 880

1967

1000 - 3500

11 - 15

FXD-335

1270 x 1100

2770

3000 - 10 000

22 - 45

FXD-400

1270 x 1100

2910

8000 - 40 000

37 - 75

19

Page 20: BATCH & CONTINUOUS MIXING - HolimexIn this brochure, we have divided the mixers according to their suitability for batch and continuous applications, ranging from low shear (gentle

The Modulomix is a continuous modular mixer based on proven Cyclomix batch mixing

technology. It has been designed specifically for the pharmaceutical industry and can be

used for low, medium or high shear applications. The Modulomix can be integrated in

a PAT (Process Analytical Technology) environment.

For decades, pharmaceutical powder ingredients have been mixed using batch

processes. However, continuous mixing is a very promising cost-saving device that can be

recommended to pharmaceutical companies looking to reduce the costs of processing.

Converting to continuous processing also introduces a lot of new considerations which

Hosokawa Micron B.V. can help you deal with. These considerations include:

• Feasibility trials

• Trials on a complete dry granulation production line

• PAT

• Defining batches in continuous processing

• Combining new processing equipment in existing production lines

• Up-scaling

• Reducing impact of start-up, change over and emergency downtime

• Minimising and dealing with off-spec product

Working principle

The Modulomix has been designed to be compact with fast reactivity, minimum residue

and rapid start-up and shutdown protocols. It produces homogeneous blending in the

blending chamber with little change to PSD (Particle Size Distribution) or temperature.

Its intensive agitation regime produces a perfect mixture with extremely short residence

times. It is fast and can be adapted to suit varying mixing conditions due to its variable

speed as well as the design of its agitator blades. Mixing Mg-stearate for example,

demands a different mixing regime to mixing drugs, which e.g. can be solved by

cascading more than one Modulomix mixers in series.

As you can see in the flow diagram, up to 3 different products can be fed into inlet 1 at

a time, thanks to the special inlet device on Modulomix 1. If required, you can also dose

additional product(s) via inlet 2 on Modulomix 1, and all of these ingredients will be

mixed efficiently by the Modulomix 1, normally under high shear conditions.

The lubricant can then be added through inlet 3 on Modulomix 1, which is directly

connected to inlet 1 on Modulomix 2. The Modulomix 2 normally has lower shear

conditions (needed for the lubricant) for creating the perfect final mix.

The final mix leaves the mixing system via a specially-designed PAT chute. Different PAT

devices can be inserted to enable continuous control of the quality of the mix.

Modular paddle mixerC

on

tinu

ou

s m

ixin

g

PAT (NIR, Raman,…)

Downstream processing like:

IBC / Container / Drum

Capsule filling

Tablet press

Dry granulation

Wet granulation

1

Exipient 1

Active 1

Active 2

other Additives

Flowagent

1

2

3

4

5

2

3

4

5

20

Page 21: BATCH & CONTINUOUS MIXING - HolimexIn this brochure, we have divided the mixers according to their suitability for batch and continuous applications, ranging from low shear (gentle

Key features

Short residence times

The design provides for very short residence times. Repeated trials have demonstrated

almost no PSD shifts and very good RSD (Relative Standard Deviation) values, even at a high

shear agitation regime. Also at low throughputs (< 1 kg/h), choosing the right feeder will

give RSD (5 sec.) values well below 5%. These values can be reduced even further by

the mixer(s).

Complete mixing system

The Modulomix has been designed to offer flexibility and adaptability as part of any

continuous blending system. With help from our expert engineers, you will have no trouble

specifying the best possible solution for all your powder processing requirements.

The Modulomix is a very compact blender that can be incorporated into Hosokawa Micron

B.V.’s total continuous blending systems. This means that you can combine the Modulomix

with Powder Transfer Systems (PTS), Loss-in-Weight (LIW) feeders, continuous blenders, PAT

technologies and even downstream processing, like (wet) granulation and / or compacting.

A continuous Modulomix system could be complemented with:

• Refill system for pharma-feeders

• Reliable and accurate pharma-feeders (set point deviation ≤ 3%)

• Specially-designed filling system for dosing multiple feeder inputs into the mixing system

• Specially-designed PAT chute and PAT monitoring device(s)

• Specially-designed on-spec/off-spec downstream switches

• Specially-designed downstream off-spec bins

• Complete and PAT integrated controls (GAMP5)

• Easy connection to any downstream processing (granulation, tablet press, compactor etc.)

Flexible

Minimum residue

Adaptable

Fast reactivity

Continuous pharma mixer

Compact

Low to high shear

Short residence times

21

Page 22: BATCH & CONTINUOUS MIXING - HolimexIn this brochure, we have divided the mixers according to their suitability for batch and continuous applications, ranging from low shear (gentle

High speed paddle mixer

The high speed paddle mixer is a horizontal, continuous mixer with paddles

located in a single helical or double helical pattern around the rotor shaft. It has

maximum tip speeds of up to 50 m/s and is very effective at dispersing materials

in a short amount of time. This high speed paddle mixer has been developed for

fine and cohesive powder applications.

Typical applications

The high speed paddle mixer is suitable for a wide variety of process applications,

including:

• Dry powder mixing

• Hydrating difficult to wet powders

• Slurry mixing

• Coating

• Sterilisation

• Crystallisation

• Agglomeration / granulation

• Homogenisation

• De-lumping and finishing

Working principle

The high speed paddle mixer consists of a horizontal rotating shaft with

protruding and adjustable paddles, enclosed in a horizontal cylindrical chamber.

It is self-cleaning; leaving no material traces behind in the machine, and operates

at low volumes.

Typical residence times range from 2 to 30 seconds, making it ideal for low

quantities. In combination with short residence times, this provides beneficial

increases in energy efficiency.

The mixing intensity of this high speed paddle

mixer can be tailored to the specific application

by adjusting paddle pitch and shaft speed.

It is a compact mixer that is capable of extremely

high heat transfer efficiency due to close contact

between the material and the heated inside

surface. It is highly suited to coating applications.

In many cases, difficult to wet proteins can be

instantised with the addition of less than

1% lecithin surfactant. In a similar process

calcium carbonate materials can be insulated or

effectively rendered insoluble with a coating of

less than 1% stearate powder.

Co

ntin

uo

us

mix

ing

22

Page 23: BATCH & CONTINUOUS MIXING - HolimexIn this brochure, we have divided the mixers according to their suitability for batch and continuous applications, ranging from low shear (gentle

EfficientVersatile

High capacity

Compact design

Flexible

High speed

Model (Ø - L) [cm]

Capacity range [m³/h]

Tip velocity [m/s]

Typical motor power [kW]

20 - 50

1.3 - 3

3.2 - 45

15

36 - 90

5 - 17

3.7 - 50

37

51 - 128

12 - 42

4 - 56

75

76 - 190

32 - 110

4 - 62

110

122 - 305

100 - 340

5 - 70

200

Models & specifications

The high speed paddle mixer is available in several models. Their typical characteristics are described below. Please note that these

values are indicative only. Detailed information is available on request.

Key features

Versatile

The high speed paddle mixer offers flexibility and adaptability for a wide

range of applications, like high-intensity mixing, coating, fine agglomeration

or continuous reaction of powders with gases. All models are available with

optional jackets for heating and cooling, with various materials of

construction from mild steel or stainless steel to special metals.

Compact design

The high speed paddle mixer is a compact paddle mixer that requires minimal

floor space and head room.

Excellent cleanability

The thin layer of material in the mixer promotes excellent indirect heat transfer

efficiency in jacketed models and a self-cleaning effect that eliminates lost product

on start-up and shut down. Sanitary construction, compliant with international

standards like EHEDG, can easily be achieved with the addition of gas-purged

split-body seals and outboard bearings.

23

Page 24: BATCH & CONTINUOUS MIXING - HolimexIn this brochure, we have divided the mixers according to their suitability for batch and continuous applications, ranging from low shear (gentle

Lab

eq

uip

men

t/A

ncilla

ries

Hosokawa Micron B.V. has an innovative range of equipment designed specifically for

laboratory and pilot plants. Our equipment offers maximum flexibility and optimum

solutions for product development and process optimisation. The equipment has been

designed for small scale laboratory use and transfer to full scale production.

Standard Hosokawa lab equipment are plug and play units. The controls are scalable

and provided with a frequency converter for variable speeds.

Lab equipment

High shear

Mid shear

Low shear

Mini Cyclomix

High shear batch mixer based on the

principles of the Cyclomix. Available in the

sizes 0.1, 1, 2 and 5 litres. The unit can be

used with a filling range of 30 - 100%.

Modulomix

The Modulomix is a continuous modular mixer with

a typical capacity of 2.5 to 10 kg/h. It is specifically

designed for the pharmaceutical industry and can

be used for low, medium or high shear applications.

Mini Flexomix

This high impact continuous mixer-agglomerator for lab

environments has a typical capacity of 25 to 200 kg/h

and is available as a single unit or as part of a total

system including, for example, liquid and powder

dosing and controls.

Mini Conical paddle mixer

Low and mid shear batch mixer available

for lab environments in sizes up to

5 litres. The unit can be used with a filling

range of 30 - 100%.

Nauta® Minimix

The famous Nauta conical mixer is also

available for use in laboratories or pilot plants

as the Nauta Minimix. This series is available in

sizes of 3.3 to 120 litres and offers the following

advantages: high mixing accuracy, gentle

mixing, complete discharge and flexible filling.

The unit can be used with a filling range of

15 - 100%.24

Page 25: BATCH & CONTINUOUS MIXING - HolimexIn this brochure, we have divided the mixers according to their suitability for batch and continuous applications, ranging from low shear (gentle

Charging hopper

Mixers can be delivered with a charging

hopper for manual charging which can be

installed on the mixer cover and is available in

two sizes: for single and dual person

operation. The standard model has been

designed with a hinged access door, bolted

grid and dust exhaust connection. 'Vibrating'

grid and/or CIP nozzles are optional.

Access door

An access door can be integrated into the

vessel wall for easy access during inspection

and cleaning. It offers a safe and ergonomic

access to the interior of the mixer and its

design guarantees an optimal dust- and

watertight closure using FDA approved

sealing.

Sampler

The Hosokawa sampler allows for powder

sampling in reactors, mixers, tanks, dryers or

similar vessels without interrupting operation.

Sampling can be carried out in a normal

atmosphere, under pressure or vacuum,

without affecting its functionality.

The sampler fits into the process vessel

without creating any dead spots and

guarantees reliable sampling.

ISEM ball segment valve

The ISEM ball segment valve is a

multi-purpose valve originally designed by

Hosokawa. The full bore passage offers a free

product discharge, without valve parts

disturbing the flow of the product. It can be

used for liquids, gases, pastes and powders,

including abrasive and aggressive applications.

Depending on the requirements it can be

delivered for use in processes under normal

atmosphere, pressure or under vacuum.

Ancillaries / options

Nau

ta ® mixer

Co

nical p

add

le mixer

Vito

mix

Cyclo

mix

Flexom

ix

Mo

du

lom

ix

Hig

h sp

eed p

add

le mixer

Option

Sampler

Heating / cooling jacket

Knockers (pneumatic / mechanic)

Charging hopper

Pressure sensor

Liquid injection

ISEM ball segment valve

Lifting device / Steel structure

Access door

Hinged cover

CIP/WIP

Level indicator

Load cells

Orbit arm positioning

Intensifier

Lump breaker

Slide gate valve

Temperature sensor

Split body

Filter

Powder and /or liquid dosing

(System) controls

Design options

Hygienic design

Sterile / aseptic design

Vacuum / pressure design

Wear / corrosion resistant design

Machine options

25

Page 26: BATCH & CONTINUOUS MIXING - HolimexIn this brochure, we have divided the mixers according to their suitability for batch and continuous applications, ranging from low shear (gentle

From concept to commissioning

We have a wide range of high-quality individual technologies for you to choose from,

but what we pride ourselves on the most, is our ability to help and support our customers

from concept to commissioning and beyond. We enjoy working in close collaboration with

our customers, and would happily help you find the optimum solution for your specific

process requirements.

We have included a number of examples of systems solutions on the following pages that

illustrate the kinds of systems we can provide. For more information on developing a

bespoke processing solution, please contact our technical advisors.

System integration

System integration is key when trying to achieve quality and efficiency in mixing. It is a

delicate balance between conveying, charging, mixing, discharging, sieving, packing and

so on, which is why we offer tailor-made mixing systems, designed and manufactured to

your exact specifications.

Preventing dust explosions

Hosokawa Micron B.V. has

realised numerous projects

under strict ATEX-conditions

and has participated in many

risk assessments. We have

ATEX certification for the

majority of the Nauta® mixers and vacuum dryers,

which guarantees safe operation in explosive

environments.

If potential ignition source(s) are unavoidable, we can

help you to implement countermeasures in the design

according to ATEX-directives.

Syste

mSo

lutio

ns

System Solutions

1

8

10

11

7

2

3

4

9

5

6

Vitomix food system

1 Liquid tank

2 Vacuum conveying system

3 Liquid injection

4 Manual charging hopper

5 Vitomix

6 Ball segment valve

7 Control sieve

8 Metal detection

9 Big bag discharge system

10 Packing machine

11 Control cabinet

26

Page 27: BATCH & CONTINUOUS MIXING - HolimexIn this brochure, we have divided the mixers according to their suitability for batch and continuous applications, ranging from low shear (gentle

AB C

AB C

1 Pump

2 Flow sensor

3 Conductivity & TOC sensors

4 Dosing pumps

5 Detergents/solvents

6 Retractable cleaning nozzle

7 Contained filling drum

8 Split valve

9 Cyclomix

10 End product drum

11 Mixer lift

12 Air filter (HEPA 13)

13 Electrical air heater

14 Control cabinet

1 Big bag discharge system

2 Hopper

3 Pneumatic transport

4 Vacuum pump

5 Filter

6 Hopper

7 LIW screw feeder

8 Container

9 Weigh belt feeder

10 Control cabinet

11 Liquid addition

12 Heated liquid addition (optional)

13 Flexomix

14 Two-way valve

15 Big bag filling station

Cyclomix inhaler system

Air

Air

Drain

Purified water

Flexomix pesticides system

9

8 116

3

13

14

12

1

2

3 7

4

5

6 8

9

13

14

15

12

10

11

5

1 2

4

7

8

10

ABC

Process configurations:

Mixing cycle

CIP-cycle

Drying cycle

27

Page 28: BATCH & CONTINUOUS MIXING - HolimexIn this brochure, we have divided the mixers according to their suitability for batch and continuous applications, ranging from low shear (gentle

Pro

cess

Au

tom

atio

nProcess AutomationProcess automation is an inextricable part of every mixing system, which is why

Hosokawa Micron B.V. has an experienced team of process and electrical engineers at

hand to help you identify the right degree of automation for your processes.

Our engineers are experts in translating process technology know-how into essential

hardware and essential software for optimum custom-made control solutions.

Qualification

Prior to the planning stage, our engineers will investigate the special demands of your

production sequence, the restrictions created by the supply network and the

environmental conditions in your production area (e.g. a potentially explosive

atmosphere, for example gas and/or dust). They will then systematically convert their

findings into a viable concept.

The diagram below illustrates the process that our engineers adopt for system

qualification.

Hardware

Selecting the correct hardware is essential for an efficient and reliable

production sequence. Our engineers combine safety, switching and operating

elements that best suit the production process and the environmental

conditions of your production site and incorporate these into your

custom-made control cabinet. It is inspected and tested before leaving

Hosokawa Micron's manufacturing facilities in terms of functionality and

quality and in accordance to international IEC and EN standards.

URS

FS

SDS

HDS IQ

OQ

PQ

Installation

IQ-protocol

OQ-protocol

PQ-protocol

28

Page 29: BATCH & CONTINUOUS MIXING - HolimexIn this brochure, we have divided the mixers according to their suitability for batch and continuous applications, ranging from low shear (gentle

Software

We then create a tailor-made software program that matches your process precisely, but is nevertheless flexible enough to allow

for quick and easy adaptations or process upgrades. The process control software is universally structured and documented. We use

tried and tested program modules for maximum reliability. These can be retrieved from libraries, permitting efficient program

generation for your process control unit.

Before the process control unit is delivered,

we carefully test the function of the software.

This means that you can concentrate fully on

process optimisation during the imple-

mentation, without having to worry about

any unwanted delays.

Process visualisation

We have two different visualisation systems

available depending on your requirements.

For simple processes, we provide a Windows-

based operating and monitoring system.

For more complicated processes, we work

with state-of-the-art process visualisation

software.

User-friendly & reliable

Hosokawa Micron's systems, hardware and software are all tried and tested. Our control solutions have been implemented

throughout a wide variety of industries. They are user-friendly, error-free and reliable, because we have reinvested the practical

experience gained from these implementations into the optimisation and improvement of our process technologies and our

automation controls.

User friendlyModular

Automation engineering

Tailormade Reliable

Practical operation

Process visualisation

29

Page 30: BATCH & CONTINUOUS MIXING - HolimexIn this brochure, we have divided the mixers according to their suitability for batch and continuous applications, ranging from low shear (gentle

The food processing industry works non-stop to develop new products that meet

product safety & quality standards, as well as traceability and all this in a competitive

market.

We offer a unique range of processing systems for the food industry including batch

and continuous mixers for laboratories and pilot plants, through to full-scale

production and complete systems solutions. Our focus is on continuing research &

development of our products and services to support you in yours.

Food Safety & Hygienic Design

Hosokawa Micron B.V. is an active participant in the European Hygienic Engineering &

Design Group (EHEDG). This is a consortium of equipment manufacturers, food

industries, research institutes and public health authorities whose goal is to increase

food safety by improving hygienic engineering and design in all aspects of food

production. The long term benefit is not only improving product safety, but also

increased durability of equipment, reduced maintenance and lower operational costs.

The food grade equipment Hosokawa Micron B.V. offers, is engineered and

manufactured in accordance with EHEDG and 3-A standards.

Food & Beverages

GelatineBaby food

Savoury products

Instant soup

Flavours & fragrancesTea

SugarSeeds

Starch

Vitamins Confectionary

Herbs & spices

Coffee

Milk powder

Ap

plica

tion

s

30

Page 31: BATCH & CONTINUOUS MIXING - HolimexIn this brochure, we have divided the mixers according to their suitability for batch and continuous applications, ranging from low shear (gentle

Applications and processes

• Mixing of infant milk powder

• Mixing, chemical and heat treatment of starch

• Mixing and sterilisation of herbs and spices

• Mixing, alkalisation and agglomeration of cocoa

• Mixing and flavouring of tea & coffee

• Homogenisation of gelatine, alginates, pectin

• Mixing and pasteurisation of egg powder

• Mixing, agglomeration and moisture manipulation of flour

• Mixing of vitamin flour and paste

• Mixing of sugar crystals and powder

• Mixing of pastes and sauces

• Coating and mixing of seeds

• Mixing of meat and fishmeal

Services

• Global development, sales and service organisation

• Process development

• Customer support by professional engineers

• Process testing, up-scaling and validation in well-

equipped test centres

• Toll production for market development

• Customised design service in accordance with EHEDG,

3-A or customers guidelines

Bakeryproducts

Spices & flavours

Cocoa

Infant formula

Spice up yourOperations

31

Page 32: BATCH & CONTINUOUS MIXING - HolimexIn this brochure, we have divided the mixers according to their suitability for batch and continuous applications, ranging from low shear (gentle

PharmaceuticalsA

pp

licatio

ns

Hosokawa Micron B.V. has a wealth of experience in pharmaceutical processing

and is up to date with the latest developments in the pharmaceutical industry and

the transition towards continuous processing. In anticipation of this changing

trend, we have developed a continuous blender, the Modulomix.

We have also been working on innovations in our batch mixing technologies to

continue improving performance and to fine tune our technologies to the latest

industry requirements, like CIP/SIP.

High standards

Reducing and managing risks and safe guarding safety has the highest priority in

the pharmaceutical industry. Complying with the industry standards like cGMP and

GAMP is a pre-requisite. Our control systems can be supplied in accordance with

the 21 CFR part 11 requirements.

The highest possible standards are crucial when it comes to hygiene, but issues like

climate controlled logistics, safety and control systems are all elements we can

discuss when helping you select the right mixer or fully-integrated mixing lines.

The low shear mixing of granules for oral applications for instance, has been

carried out in the well-known Nauta® mixers for a long time. For high shear mixing

of dry powder Inhalers, you should choose the Cyclomix.

Upscaling

Our equipment is available in sizes suitable for R&D, clinical trials as well as for

manufacturing; and we will happily support you with process up-scaling if required.

• Laboratory scale batches: 0.1 - 5 litres

• Development scale batches: 1 - 120 litres

• Manufacturing scale batch size: 25 - 10 000 litres

Uniform dosage forms

NanopharmaceuticalsRespiratory drugs (DPI)

Sterile intravenous drugs

API

Excipients such as lactose, sugar, cellulose

Veterinary products

Tooth paste

Cell culture media

Parenterals

32

Page 33: BATCH & CONTINUOUS MIXING - HolimexIn this brochure, we have divided the mixers according to their suitability for batch and continuous applications, ranging from low shear (gentle

Special care for your products

Applications and processes

• Batch mixing of active ingredients and excipients and or

lubricants for oral applications

• Formulation of active ingredients and excipients for Dry

Powder Inhalers

• Continuous mixing of active ingredients and excipients.

• Coating of fine bulk carrier with liquids and/or nano

active ingredients

• Mixing of excipients like lactose with lubricants before

tablet press

• Mixing / dispersion systems for cosmetic facial powders

• Mixing of wet and dry granulated material with lubricant

• Heat treatment or cooling of powders

• Addition of moisture

• Mixing of nutraceutical products like vitamins

• Sterilisable systems

Services

• Global organisation and support

• Process development support and testing facilities

• Rental equipment available for testing purposes

• Scale up support from lab to industrial production

• Our systems comply with the latest international

standards

• Customised system design

• CIP/SIP functionality

• Validation documentation

Drug discovery & development

Phase 1

Phase 2

Phase 3

Phase 4

Lab testing

Equipment development

Production of equipment

33

Page 34: BATCH & CONTINUOUS MIXING - HolimexIn this brochure, we have divided the mixers according to their suitability for batch and continuous applications, ranging from low shear (gentle

Ap

plica

tion

sThe field of activity of the chemicals division is just as wide and diverse as the

overwhelming number of substances for which Hosokawa Micron B.V. offers mixing

solutions. The mixing process in the chemical industry is often critical, demanding

the highest of industry standards. Three important aspects worthy of special

attention are flexibility, reliability and safety.

Flexibility

As product life cycles shorten, production facilities in the chemical industry need to

be equipped for making easy adjustments for the manufacture of alternative

products. Our mixers and system solutions are designed for this very purpose: for

handling a wide range of different materials with varying product properties.

Safety

The chemical industry synonymous with hazardous materials, and mixing them is a

specialist field. Needless to say, Hosokawa Micron B.V. is expert in this field, and works

to stringent safety standards for all of its products and process systems.

Reliability

We offer state-of-the-art technology that has proven to be highly efficient and

extremely reliable. Every system is engineered for high performance with maximal

durability and minimal downtime. To ensure this, we always apply adequate

measures for maximal safety, for your product, the operator and the environment.

Chemicals

Pigments

Catalysts

Dicalcium phosphate

Magnesium hydroxide

PE resin

Acrylates

CMC

Zeolite

Titanium dioxide

PVCMetal stearates

Copper hydroxide

34

Page 35: BATCH & CONTINUOUS MIXING - HolimexIn this brochure, we have divided the mixers according to their suitability for batch and continuous applications, ranging from low shear (gentle

Applications and processes

• Batch mixing of pesticides

• Batch mixing of conventional and chemically produced

toner (CPT)

• Continuous mixing (crosslinking) of super absorbent

polymers (SAP)

• Continuous mixing and agglomeration of detergent powders

• Continuous mixing and agglomeration of soil improvers

• Mixing of recycled and virgin polymer

• Batch mixing / coating of flame retardant

• Homogenisation of battery mass

• Dispersion of pigments

• Coating of magnesium hydroxide

• Master batching of polymer and pigments

Services

• Global organisation and support

• Application and process development

• Process simulation to prove product quality and

process functionality

• Up-scaling from pilot to industrial scale

• From single unit to turnkey system

• Dedicated project management

• A variety of contract production services

• Toll processing

Feel thechemistry

Pigments

Catalysts

Agrochemicals

Super Absorbent Polymers (SAP)

35

Page 36: BATCH & CONTINUOUS MIXING - HolimexIn this brochure, we have divided the mixers according to their suitability for batch and continuous applications, ranging from low shear (gentle

Hosokawa Micron B.V. provides the minerals and metals industry with a wide

range of reliable and robust mixing equipment. We offer proven technologies

and have the know-how and experience for successful operational concepts for

all kinds of product. We know how important high productivity, reliability and

low operational costs are, and enjoy finding the optimum solutions for our

customers.

Productivity

Batch processing in large volume mixers is often the most suitable solution for

large quantity mixing. For these applications, we recommend mixers with low

power requirements such as the Nauta® conical screw mixer. The low power

requirements result in improved energy efficiency, as well as reduced wear.

Another way of processing large batches, is by mixing smaller volumes with very

short batch times. The Cyclomix is ideal for this. For continuous mixing, we can

provide compact mixers that are extremely accurate at mixing large volumes.

The Flexomix and the continuous paddle mixer are two good examples.

Wear protection

Energy consumption and replacement due to wear are two of the biggest

operational costs in the minerals and metals industry. To combat this, the Nauta

conical screw mixer has been designed to consume very little energy, which in

turn reduces the amount of abrasion inside the mixer. For highly abrasive

applications, parts can also be protected against wear, which can optimise life

cycle costs even further.

We recommend wear protection if you deal with high-intensity batch and/or

high-speed continuous mixing.

Minerals & MetalsA

pp

licatio

ns

Talc

Zircon sand

Gypsum

GraphiteRare earths elements

BentoniteFeldspar

Kaolin

Ceramics

Metal powders

Calcium carbonate

Zeolite

36

Page 37: BATCH & CONTINUOUS MIXING - HolimexIn this brochure, we have divided the mixers according to their suitability for batch and continuous applications, ranging from low shear (gentle

Applications and processes

• Batch mixing of metal powders with bulk density up

to 3.5 kg/l

• Batch mixing of cement slurry and pigments

• Mixing of metal or oxide powders and pastes for

products like iron, aluminium and bronze

• High accuracy mixing of minerals and metals with

additives, pigments or flow agents before sintering,

calcinations or compaction

• Coating of calcium carbonate

• Coating of magnesium carbonate

Services

• Global organisation and support

• Process development

• Process simulation for product quality and process

functionality

• Testing & Tolling

• Contract production

• Single units to turnkey systems

Rock solidsolutions

Cement

Metal powders

Ceramics

Welding powders

37

Page 38: BATCH & CONTINUOUS MIXING - HolimexIn this brochure, we have divided the mixers according to their suitability for batch and continuous applications, ranging from low shear (gentle

Hosokawa Micron B.V. has its own testing and development centre in Doetinchem,

the Netherlands. It offers unique possibilities for testing your product to determine the

most efficient process, system or plant prior to final design. We can provide laboratory as

well as production-sized trials.

Whether you wish to test a single machine or a complete powder processing system,

the same skilled and experienced staff are here to help ensure that your requirements are

met, and that you are entirely satisfied with the results.

We have test equipment at your disposal for:

• Batch mixing from 1 up to 6000 litres

• Continuous mixing from 2.5 up to 1000 kg/h

• Batch vacuum drying from 5 up to 6000 litres

• Batch freeze drying of 1.5, 5 and 60 litres

• Continuous drying from 1 up to 250 kg/h (evaporation)

• Batch agglomeration from 5 up to 500 litres

• Continuous agglomeration from 50 up to 500 kg/h

Is testing necessary?

If we could summarise the behaviour of powders in a set of rules and guidelines, in other

words, if results could be predicted, then testing would be unnecessary. Of course the

reality is somewhat different. Testing isn’t only necessary; it is the foundation of any

successful product or process. At Hosokawa Micron B.V., we enjoy helping our customers

test their latest ideas and requirements and with our modern testing facilities, we can help

you put theory into practice.

Testin

g &

Tollin

gTesting & Tolling

38

Page 39: BATCH & CONTINUOUS MIXING - HolimexIn this brochure, we have divided the mixers according to their suitability for batch and continuous applications, ranging from low shear (gentle

Toll processing & Contract manufacturing

Besides testing, we also offer a wide range of toll processing & contract manufacturing services ranging from single to multiple

processes, for batch and continuous mixing, drying and agglomeration.

Your advantages:

• Clearly defined costs

• No investment in equipment and buildings

• Efficient production of small quantities

• Test your process on a lab and production scale

• Define the specifications of your machine

• Use toll processing as part of your development process

• Produce materials for marketing activities, prior to investing in new production capacity

• Fill the gap between design and start up of your new equipment or plant

• Launch new products using toll processing, until your sales have reached a solid and profitable base

Rental equipment

Our testing centre is full-equipped with all of our latest equipment for operational trials but we also offer a range of rental equipment

so that you can carry out operational trials at your own facilities too. This means that you can fine tune process parameters and monitor

production flows prior to finalising equipment choices and process designs. To help things go smoothly, our experienced process

engineers will work closely with your engineering team to advise and develop the best solution for your processing requirements.

For more information and availability please contact us.

Rental equipment

Testing

Toll processingContract manufacturing

Laboratory- and production scale trials39

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Service & SupportServ

ice &

Su

pp

ort

Reliable24 hrs service & support

Repair

Predictable

Value for moneyUpgradeAvoid down-time

Improve Replace +31 (0)314 37 35 05

Downtime is unacceptable, which is why customers demand security and peace of mind

for their processes and service and support for their machinery. Hosokawa Micron B.V.

can pride itself on a highly-competent engineering department and a responsive and

smoothly operating service department.

Repair & maintenance

Our Technical Services Team carries out repair and maintenance services onsite or in our own fully-equipped workshop in Doetinchem,

the Netherlands. This team comprises specialists in mechanical engineering, maintenance, instrumentation and controls as well as process

engineering.

Protect your investment

Create added security for your capital investment with one of our regular maintenance contracts. Our sales engineers will be more than

happy to discuss a bespoke agreement that meets your specific maintenance needs, either for single machines or entire process lines.

Spare Parts Service

Minimise the hassle of sourcing spare parts with our Spare Parts Service. We have a team of engineers on standby that can deliver the spare

parts and install them for you on site. And if that isn't efficient enough, we will happily discuss the options for your own in-house Hosokawa

Micron B.V. inventory: spare parts to hand, 24/7.

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On site services

• Preventative maintenance

• Inspection and troubleshooting

• Repair & service

• Process support and optimisation

• Modifications and upgrading to latest technology

• Internal transport, relocation and construction

• Operator training either onsite or in Doetinchem,

the Netherlands

• Commissioning

• Certification and validation

• Reconditioning of used machines

• Swap drives

Preventative maintenance

Preventative maintenance means knowing that your production processes are in good working order and increasing the lifetime

of your plant. Hosokawa Micron B.V. has a dedicated team of experienced maintenance engineers specialised in just this: providing

on-site advice, engineering and training to help you optimise your processes. Our experienced engineers are focussed on identifying

potential mechanical, safety and process line problems before they cause unnecessary downtime.

Replacing old machinery with new

A retrofit, upgrade or refurbishment can be easier and more economical than specifying and buying new. Hosokawa Micron B.V. offers

exactly that: a combination of our high-quality products and spare parts with expert design and engineering as well as experienced

manpower. Our goal is to make sure you are left with equipment that performs at the same level as the brand-new equivalent.

Retrofitting

We will send in our expert engineers for an initial assessment, fix mechanical failures and replace broken parts. In short, we will give

your machines a new lease of life. Any new parts come with a 12-month guarantee but may well last much longer; 25-30 years is no

exception! That's what we call value for money.

Upgrading

Our engineers can also help you improve production, increase capacity and upgrade your existing processes to the latest industry

standards. We can minimise mechanical failures, convert to food-grade specifications and CIP cleaning, all without necessarily having

to replace the entire system.

Refurbishment

Refurbishment is more than a retrofit or upgrade. It's the whole package. From start to finish, we will work with you to improve your

processes: come up with a plan, improve, repair, replace and upgrade whilst considering the application, the market sector, industry

standards and of course your wishes and requirements.

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CONTACT

Hosokawa is the world’s largest

provider of processing systems for the

field of powder and particle

processing. Renowned brand names

such as Alpine, Micron, Nauta, Schugi,

Stott, Vitalair and Vrieco are all

included in the Group’s range.

Regardless of the size, i.e. production-

scale systems, pilot systems or

laboratory equipment, Hosokawa’s

products and technologies are used in

numerous process stages, for example

during mixing, drying, agglomeration,

containment, filling, metering, size

reduction and classification.

Hosokawa Sales Office

Hosokawa Engineering / Manufacturing / Test Centre

Hosokawa Micron Powder Systems S.A. de C.V. Mexico City (Mexico)

Hosokawa Micron Polymer Systems, Berlin, CT (USA)

Hosokawa Micron Powder Systems, Summit, NJ (USA)

H O S O K A W A M I C R O N G R O U P W O R L D W I D E

42

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CONTACT

Hosokawa Micron France Évry (France)

Hosokawa Micron Ltd.Runcorn (UK)

H O S O K A W A M I C R O N G R O U P W O R L D W I D E

Hosokawa Micron B.V., Doetinchem (Netherlands)

Hosokawa Micron Ltd., Seoul (South Korea)

Hosokawa Micron SDN BHD,Kuala Lumpur (Malaysia)

Hosokawa Alpine AG, Augsburg (Germany)

Hosokawa Alpine Compaction, Leingarten (Germany)

HOSOKAWA MICRON CORPORATION, OSAKA (JAPAN)

Headquarters

NETHERLANDS

Hosokawa Micron B.V.

Gildenstraat 26

P.O. Box 98

7000 AB Doetinchem

+31 314 373 333

[email protected]

www.hosokawamicron.nl

TEAM CHEMICALS/MINERALS/METALS

+31 314 373 460

[email protected]

TEAM FOOD

+31 314 373 463

[email protected]

TEAM PHARMA

+31 314 373 461

[email protected]

TEAM SERVICE

+31 314 373 372

+31 314 373 374

[email protected]

After office hours

+31 314 373 505

Hosokawa Micron Pvt. Ltd.Chennai (India)

Hosokawa Micron Powder Machinery Co. Ltd., Shanghai (China)

Hosokawa Micron St. Petersburg OOO (Russia)

Hosokawa MicronBangkok (Thailand)

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HMBV.MIX.ENG.19.06

Hosokawa Micron B.V. is a member of the Hosokawa Micron Group,

responding to global needs through emphasis on materials science and

engineering. The Group is an international provider of equipment and

technology for powder and particle processing, plastics processing and

confectionery products. The Group maintains facilities for research,

engineering, manufacturing and service in each of the world’s major

industrial markets.

© Hosokawa Micron B.V. Doetinchem, Netherlands