‐the largest exclusively cave animal ... - proteus genome€¦ · 1 ‐sex determination sex...
TRANSCRIPT
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‐ The largest exclusively cave animal‐ Top predator ‐ indicator of stable food chains and water quality‐ Symbol of natural heritage and underground biodiversity‐ Endangered by pollution and loss of habitat‐ Endemic to Dinaric Karst
Proteus anguinus
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1 ‐ SEX DETERMINATION
Sex ratio and demographic structure of natural populations
POTENTIAL OUTCOMES OF “PGP” IN A VIEW OF PROTEUS CONSERVATION
Establishment of sustainable breeding program
PGP ‐ genetic markers for sex determination
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2 ‐ HOW MANY POPULATIONS/SPECIES OF PROTEUS ARE THERE?
3 ‐ HOW LARGE AND HOW STABLE ARE THESE POPULATIONS?
OPTIMISATION OF CONSERVATION STRATEGIES
PGP ‐ estimation of genetic diversity of populations and trends of their dynamics
PGP ‐ genetic markers that would allow distinguishing between populations
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EXTREME STARVATION AND FEEDING
PGP ‐ potential to improve our understanding of mechanisms behind starvation, metabolic abnormalities and other
adaptations to cave environment, as well as their relevance for human health
‐ Starvation without an anorexia‐ Overeating without becoming obese
… tend to be features of cave organisms
OTHER POTENTIAL OUTCOMES OF “PGP”
Astyanax mexicanus
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REGENERATION
PGP ‐ may ease the search of mechanisms behind regeneration ‐with a prospect of development of novel biomedical approaches
‐ full regeneration of damaged or missing organs is a common feature of salamanders
Ambystoma mexicanum
Pleurodeles waltl
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LONGEVITY
‐ the longest lifespan among amphibians
PGP ‐ potential to illuminate the mechanisms behind longevity through genetic differences
between Proteus and other amphibians
‐ one of the largest genomesGENOME SIZE
PGP ‐ knowing the structure of genome may contribute to understanding the purpose and origin
of non‐coding segments of genomes
Necturus maculatus Lepidosiren paradoxa
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https://www.proteusgenome.com/