At Risk of Anaphylaxis – Ready, or Not? .

Summary Report October 15, 2012

Account Manager: Associate Vice President:

Lisa Sookram lsookram@legermarketing.com Lisa Covens lcovens@legermarketing.com 416.815.0330

6

INSTRUMENT The survey was completed on-line from August 27, 2012 to September 15, 2012 using Leger Marketing’s online panel, LegerWeb, with a sample of 565 Canadian adults at risk of anaphylaxis and 524 Canadian parents of children at risk for anaphylaxis (366 mothers and 158 fathers). A probability sample for adults at risk of anaphylaxis of the same size would yield a margin of error of ±4.1 %, 19 times out of 20. A probability sample of parents of children at risk for anaphylaxis of the same size would yield a margin of error of ±4.3 %, 19 times out of 20. ONLINE PANEL Leger Marketing’s online panel has approximately 400,000 members nationally – with between 10,000 and 20,000 new members added each month, and has a retention rate of 90%. Panel members are randomly selected to receive email invitations to the individual surveys. We ensure the protection of privacy via the usage of unique URLs and respondent IDs in combination with survey IDs.

QUALITY CONTROL Stringent quality assurance measures allow Leger Marketing to achieve the high-quality standards set by the company. As a result, its methods of data collection and storage outperform the norms set by WAPOR (The World Association for Public Opinion Research). These measures are applied at every stage of the project: from data collection to processing, through to analysis. We aim to answer our clients’ needs with honesty, total confidentiality, and integrity.

8

At Risk of Anaphylaxis – Ready, or Not?

Among those at risk of anaphylaxis in Canada: • More than half do NOT always carry or have immediate access to an

epinephrine auto-injector. • More than one-quarter feel they would panic if they or their child had an

anaphylactic reaction. • A significant number say they are uncertain and lack confidence in their

ability to correctly use an auto-injector. • Almost half of the adults and two-thirds of the parents worry that others will

not know how to use an auto-injector in an emergency. • One-quarter of parents worry about their ability to administer the auto-injector

to their child.

Throughout this report, the term ‘adults’ refers to adults at risk of anaphylaxis, and the term ‘parents’ refers to parents with children at risk of anaphylaxis. Both of these groups were surveyed by Leger Marketing.

Level of Compliance 10

Q5. Which of the following best describes your behaviour with respect to your epinephrine auto-injector?/ Which of the following best describes the behaviour of the person responsible for carrying your child’s epinephrine auto-injector? Base: Total (n= 1089).

57% do not

always carry an

auto-injector

All Respondents (n=1089) Adults (n=565) Parents (n=524)

Overall, 57% do NOT always carry an epinephrine auto-injector as recommended by physicians. By group, 63% of adults and 51% of parents do NOT have an auto-injector immediately available at all times.

63% of adults do not always

carry an auto-

injector

51% of parents do not always

carry an auto-

injector

How often do you carry your/your child’s epinephrine auto-injector?

11

Net agree 27%

All Respondents (n=1089) Adults (n=565) Parents (n=524)

Q7/ Q14. To what extent do you agree with each of the following statements:

Net agree 27%

Net agree 27%

Likely to Panic

27% feel they would likely panic in the event they or their child had an anaphylactic reaction.

12

16% are not confident

in their ability to correctly

use auto-injector

All Respondents (n=1089) Adults (n=565) Parents (n=524)

16% overall (19% of adults and 14% of parents) say they are not confident in their ability to correctly use the auto-injector.

Lack of Confidence

19% of adults are not

confident in their ability to correctly use their auto-

injector

14% of parents are not confident in their ability to

correctly use their child’s

auto-injector

Q7/ Q14. To what extent do you agree with each of the following statements:

26% of parents worry about their ability to administer an auto-injector to their child.

13

Net Agree 26%

Net Disagree

74%

Q7/ Q14. To what extent do you agree with each of the following statements: Base: Parents of children at risk of anaphylaxis (n= 524).

Worried About Administering an Auto-Injector to a Child

14

Net agree 56%

All Respondents (n=1089) Adults (n=565) Parents (n=524)

56% overall (47% of adults and 64% of parents) worry that others will not know how to use an auto-injector in an emergency.

Net agree 47%

Net agree 64%

Q7/ Q14. To what extent do you agree with each of the following statements:

Worried Others Will Not Know What to Do

15

16% are uncertain

about how to use their/their

child’s auto-injector

All Respondents (n=1089) Adults (n=565) Parents (n=524)

16% overall (19% of adults and 13% of parents) say they are uncertain about how to use an auto-injector.

Uncertainty

19% of adults are uncertain about how to

use their auto-injector

13% of parents are uncertain

about how to use their child’s

auto-injector

Q7/ Q14. To what extent do you agree with each of the following statements:

16

Net agree 43%

All Respondents (n=1089) Adults (n=565) Parents (n=524)

More than 40% of patients and parents say people around them/their children are likely to panic in an anaphylactic emergency.

Net agree 43%

Net agree 42%

Q7/ Q14. To what extent do you agree with each of the following statements:

Worried Others Will Panic

Regional Differences

• 48% of Quebecers do NOT always carry an auto-injector at all times. • 28% of people in Quebec feel they would likely panic in the event

they or their child had an anaphylactic reaction.

• However, only 13% say they are not confident in their ability to correctly use the auto-injector.

• Nearly half, 47% worry that others will not know how to use an auto-injector in an emergency.

18

Regional Differences – Quebec

• 57% of Ontarians do NOT always carry an auto-injector at all times. • 23% of people in Ontario feel they would likely panic in the event they or their child had an anaphylactic reaction.

• 16% say they are not confident in their ability to correctly use the auto-injector.

• Most Ontarians (57%) worry that others will not know how to use an auto- injector in an emergency.

19

Regional Differences – Ontario

• 63% of Western Canadians do NOT always carry an auto-injector at all times. • A third (32%) feel they would likely panic in the event they or their child had an anaphylactic reaction.

• 19% say they are not confident in their ability to correctly use the auto-injector.

• 59% of Western Canadians worry that others will not know how to use an auto-injector in an emergency.

20

Regional Differences – Western Canada

• 61% of Atlantic Canadians do NOT always carry an auto-injector at all times. • 23% feel they would likely panic in the event they or their child had an anaphylactic reaction.

• 16% say they are not confident in their ability to correctly use the auto-injector.

• 56% of Atlantic Canadians worry that others will not know how to use an auto-injector in an emergency.

21

Regional Differences – Atlantic Canada

Demographic Differences

• Men are more likely to say they rarely/never carry an auto-injector compared to women (18% vs. 13%).

• Women are more likely to panic than men (32% vs. 18%) and mothers are more likely to panic than fathers (30% vs. 18%) in the event of an anaphylactic reaction.

• Those 18-34 are more likely to say they are uncertain about how to use an auto-injector compared to those 35-54 (24% vs.13%).

23

Demographic Differences

Demographics: Combined Adult and Parent Data

Male 30%

Female 70%

Age

18-24 years of age 1%

25-34 years of age 13%

35-44 years of age 22%

45-54 years of age 27%

55-64 years of age 24%

65-74 years of age 11%

75 years of age or older 2%

TOTAL RESPONSES 26

Household Income

$19,999 or less 4%

Between $20,000 and $39,999 10%

Between $40,000 and $59,999 15%

Between $60,000 and $79,999 14%

Between $80,000 and $99,999 14%

$100,000 or more 24%

I prefer not to answer 19%

Status

Married or living together 75%

Single 9%

Divorced 7%

Widowed 4%

Separated 4%

I prefer not to answer 1%

TOTAL RESPONSES 27

Highest Education Obtained

High School, general or professional (8 to 12 years) 14%

College pre-university, technical training, certificate (CEP 32%

University Bachelor's degree (including classical studies) 31%

University Master's degree 10%

University certificates and diplomas 9%

University Doctorate (PhD) 2%

I prefer not to answer 1%

Occupational Status

Working full time 45%

Retired 22%

Working part time 9%

Self-employed or business owner 9%

Homemaker 8%

Unemployed 4%

Student 1%

I prefer not to answer 2%

TOTAL RESPONSES 28

How many children do you have?

Yes, I have children 83%

One 15%

Two 39%

Three 20%

Four 6%

Five 2%

Six 1%

I am not a parent/ do not have children 17%

TOTAL RESPONSES 29

Age of Children in Household YES 44%

Yes: 12 years of age and OLDER ONLY 15%

Yes: 12 years of age and older AND younger than 12 years old 6%

Yes: YOUNGER than 12 years old ONLY 23%

No children under 18 years old at all in the household 52%

I prefer not to answer 2%

No answer 2%

How old are your children?

Less than 1 year old 5%

1-5 23%

6-12 24%

13-17 22%

18-21 16%

Over 21 41%

Prefer not to answer 12%

TOTAL RESPONSES 30

Saskatchewan 3%

Alberta 9% Manitoba

6%

Nunavut Northwest territories

Briti

sh C

olom

bia

14%

Ontario 38%

Quebec 23%

Newfoundland & Labrador

1%

New Brunswick

2%

Nova Scotia/PEI 4%

Yukon

Regional Breakdown (Total number of responses = 1,089)

Description of area

Large Urban (25,000+) 61%

Medium Urban (10,000 to 25,000) 15%

Town (less than 10,000) 11%

Rural area 13%

31

Demographics: Adults

Male 29%

Female 71%

33 ADULTS AT RISK OF ANAPHYLAXIS

Age of Adult at Risk

18-24 years of age 2%

25-34 years of age 10%

35-44 years of age 13%

45-54 years of age 26%

55-64 years of age 30%

65-74 years of age 17%

75 years of age or older 3%

34

Household Income

$19,999 or less 6%

Between $20,000 and $39,999 11%

Between $40,000 and $59,999 18%

Between $60,000 and $79,999 16%

Between $80,000 and $99,999 14%

$100,000 or more 18%

I prefer not to answer 18%

Status

Married or living together 67%

Single 15%

Divorced 9%

Widowed 6%

Separated 3%

ADULTS AT RISK OF ANAPHYLAXIS

Highest Education Obtained

High School, general or professional (8 to 12 years) 17%

College pre-university, technical training, certificate (CEP 33%

University certificates and diplomas 9%

University Bachelor's degree (including classical studies) 28%

University Master's degree 9%

University Doctorate (PhD) 2%

I prefer not to answer 2%

35 ADULTS AT RISK OF ANAPHYLAXIS

Occupational Status

Working full time 38%

Working part time 8%

Self-employed or business owner 10%

Student 1%

Homemaker 4%

Unemployed 5%

Retired 32%

I prefer not to answer 2%

36

How many children do you have?

Yes, I have children 68%

One 18%

Two 29%

Three 15%

Four 4%

Five 1%

Six 1%

I am not a parent/ do not have children 32%

How old are your children? (n= 385)

Less than 1 year old 2%

1-5 9%

6-12 10%

13-17 12%

18-21 14%

Over 21 63%

Prefer not to answer 11%

ADULTS AT RISK OF ANAPHYLAXIS

37

Age of Children in Household YES 19%

Yes: 12 years of age and OLDER ONLY 6%

Yes: 12 years of age and older AND younger than 12 years old 3%

Yes: YOUNGER than 12 years old ONLY 10%

No children under 18 years old at all in the household 78%

I prefer not to answer 1%

No answer 2%

ADULTS AT RISK OF ANAPHYLAXIS

Saskatchewan 3%

Alberta 9% Manitoba

5%

Nunavut Northwest territories

Briti

sh C

olom

bia

14%

Ontario 40%

Quebec 18%

Newfoundland & Labrador

1%

New Brunswick

3%

Nova Scotia/PEI 7%

Yukon

Regional Breakdown (ADULTS AT RISK OF ANAPHYLAXIS)

Description of area

Large Urban (25,000+) 63%

Medium Urban (10,000 to 25,000) 13%

Town (less than 10,000) 11%

Rural area 14%

38

Demographics: Parents of

children with anaphylaxis

Fathers 30%

Mothers 70%

40 PARENTS OF CHILDREN AT RISK OF ANAPHYLAXIS

Age of Parent of Child at Risk

25-34 years of age 16%

35-44 years of age 31%

45-54 years of age 29%

55-64 years of age 18%

65-74 years of age 6%

75 years of age or older 1%

41

Household Income

$19,999 or less 2%

Between $20,000 and $39,999 9%

Between $40,000 and $59,999 12%

Between $60,000 and $79,999 11%

Between $80,000 and $99,999 15%

$100,000 or more 31%

I prefer not to answer 21%

Status

Married or living together 84%

Divorced 6%

Separated 4%

Widowed 3%

Single 2%

I prefer not to answer 1%

PARENTS OF CHILDREN AT RISK OF ANAPHYLAXIS

Highest Education Obtained

College pre-university, technical training, certificate (CEP 32%

University certificates and diplomas 9%

University Bachelor's degree (including classical studies) 34%

University Master's degree 12%

University Doctorate (PhD) 2%

I prefer not to answer 1%

High School, general or professional (8 to 12 years) 11%

42

Occupational Status

Working full time 52%

Homemaker 12%

Working part time 11%

Retired 11%

Self-employed or business owner 9%

Unemployed 3%

Student 1%

I prefer not to answer 2%

PARENTS OF CHILDREN AT RISK OF ANAPHYLAXIS

43

How many children do you have?

Yes, I have children 100%

One 12%

Two 49%

Three 26%

Four 8%

Five 3%

Six 1%

I am not a parent/ do not have children 1%

PARENTS OF CHILDREN AT RISK OF ANAPHYLAXIS

How many children do you have that are at risk of anaphylaxis? 1 91%

2 8%

3 2%

44

Age of Children in Household YES 72%

Yes: 12 years of age and OLDER ONLY 24%

Yes: 12 years of age and older AND younger than 12 years old 10%

Yes: YOUNGER than 12 years old ONLY 38%

No children under 18 years old at all in the household 23%

I prefer not to answer 3%

No answer 2%

PARENTS OF CHILDREN AT RISK OF ANAPHYLAXIS

How old are your children? (n= 385)

Less than 1 year old 6%

1-5 32%

6-12 35%

13-17 29%

18-21 18%

Over 21 24%

Prefer not to answer 12%

45 PARENTS OF CHILDREN AT RISK OF ANAPHYLAXIS

Which of the following, if any, do you do with respect for your child’s allergies? (Fathers= 155)

I ensure that adults around my child (teachers, other parents, friends, extended family) are aware of my child's allergies

87%

I make sure my child avoids their allergens 81%

I remind my child to carry their epinephrine auto-injector 70%

I carry my child's epinephrine auto-injector for them 36%

Saskatchewan 3%

Alberta 9% Manitoba

6%

Nunavut Northwest territories

Briti

sh C

olom

bia

14%

Ontario 36%

Quebec 28%

Newfoundland & Labrador

1%

New Brunswick

1%

Nova Scotia/PEI 1%

Yukon

Regional Breakdown (PARENTS OF CHILDREN AT RISK OF ANAPHYLAXIS)

Description of area

Large Urban (25,000+) 60%

Medium Urban (10,000 to 25,000) 17%

Town (less than 10,000) 10%

Rural area 12%

46