assoc. prof. sinan canan - aybu.edu.tr · motor cortex primary motor cortex primary source for the...

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Assoc. Prof. Sinan Canan [email protected] http://sinancanan.net

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Page 1: Assoc. Prof. Sinan Canan - aybu.edu.tr · Motor Cortex Primary motor cortex Primary source for the motor commands to lower motor neurons. Somatotopical organization “Motor homunculus”

Assoc. Prof. Sinan Canan [email protected]

http://sinancanan.net

Page 2: Assoc. Prof. Sinan Canan - aybu.edu.tr · Motor Cortex Primary motor cortex Primary source for the motor commands to lower motor neurons. Somatotopical organization “Motor homunculus”

Motor Cortex  Center of voluntary motor

movements   Located anterior to the

central sulcus   Includes;

 Primary motor cortex  Premotor area  Supplementary motor

area

Page 3: Assoc. Prof. Sinan Canan - aybu.edu.tr · Motor Cortex Primary motor cortex Primary source for the motor commands to lower motor neurons. Somatotopical organization “Motor homunculus”

Motor Cortex  Primary motor cortex

 Primary source for the motor commands to lower motor neurons.

 Somatotopical organization

  “Motor homunculus”

 Finer muscle control – more motor units – more motor neurons – larger representation areas

Page 4: Assoc. Prof. Sinan Canan - aybu.edu.tr · Motor Cortex Primary motor cortex Primary source for the motor commands to lower motor neurons. Somatotopical organization “Motor homunculus”

Motor Cortex

 Premotor area   Topografic organization   Complex movement patterns   Construction of “motor image”

 Supplementary motor area   Bilateral complex movement patterns   Body posture maintanence

Page 5: Assoc. Prof. Sinan Canan - aybu.edu.tr · Motor Cortex Primary motor cortex Primary source for the motor commands to lower motor neurons. Somatotopical organization “Motor homunculus”

Motor Cortex

F5

Page 6: Assoc. Prof. Sinan Canan - aybu.edu.tr · Motor Cortex Primary motor cortex Primary source for the motor commands to lower motor neurons. Somatotopical organization “Motor homunculus”

Mirror neuron system

Page 7: Assoc. Prof. Sinan Canan - aybu.edu.tr · Motor Cortex Primary motor cortex Primary source for the motor commands to lower motor neurons. Somatotopical organization “Motor homunculus”

Motor Cortex

 Cortical columns   Motor patterns for synergistic

muscle groups   Stimulus amplification for

contraction  Dynamic and static neurons

  In motor cortex and Red nucleus (n. Ruber)   Dynamic neurons: Building up force

at the beginning   Static neurons: Maintain the

movement or posture

Page 8: Assoc. Prof. Sinan Canan - aybu.edu.tr · Motor Cortex Primary motor cortex Primary source for the motor commands to lower motor neurons. Somatotopical organization “Motor homunculus”

Corticospinal tract

Page 9: Assoc. Prof. Sinan Canan - aybu.edu.tr · Motor Cortex Primary motor cortex Primary source for the motor commands to lower motor neurons. Somatotopical organization “Motor homunculus”

Motor Cortex  Betz cells

  3% of the pyramidal tract

Page 10: Assoc. Prof. Sinan Canan - aybu.edu.tr · Motor Cortex Primary motor cortex Primary source for the motor commands to lower motor neurons. Somatotopical organization “Motor homunculus”

Corticospinal tract

 Axons of corticospinal tract  Primary motor cortex (30%)  Premotor&Supp. Motor areas (30%)  Somatosensory areas (40%)

Page 11: Assoc. Prof. Sinan Canan - aybu.edu.tr · Motor Cortex Primary motor cortex Primary source for the motor commands to lower motor neurons. Somatotopical organization “Motor homunculus”

Other motor pathways

 Collaterals of Betz cells (lateral inhibition)  To Basal ganglia (postural contractions)  To Red nucleus (→rubrospinal tract)  To Reticular system (→ reticulocerebellar tracts)  To Vestibular system (→ vestibulocerebellar tracts)  To Pons nuclei (→ pontocerebellar tracts)  To Nuc. olivarius inferior (→ olivocerebellar tracts)

Page 12: Assoc. Prof. Sinan Canan - aybu.edu.tr · Motor Cortex Primary motor cortex Primary source for the motor commands to lower motor neurons. Somatotopical organization “Motor homunculus”

Corticospinal tract

  Lateral system   Pyramidal tract   Rubrospinal tract

  Alternative/complementary

  Movements of distal extremities

Page 13: Assoc. Prof. Sinan Canan - aybu.edu.tr · Motor Cortex Primary motor cortex Primary source for the motor commands to lower motor neurons. Somatotopical organization “Motor homunculus”

Corticospinal excitation

Page 14: Assoc. Prof. Sinan Canan - aybu.edu.tr · Motor Cortex Primary motor cortex Primary source for the motor commands to lower motor neurons. Somatotopical organization “Motor homunculus”

Sensory Feedback

 From muscle spindles…  From tendon organs…  From skin-touch receptors…

Page 15: Assoc. Prof. Sinan Canan - aybu.edu.tr · Motor Cortex Primary motor cortex Primary source for the motor commands to lower motor neurons. Somatotopical organization “Motor homunculus”

Motor Control from Brainstem

  “Defying gravity”   Pontine reticular nuclei

(spontaneous exitatory signals to antigravity muscles)

  Medullary reticular nuclei (strong cortical input; inhibitory signals via medullary reticulospinal tr.)

  Vestibular nuclei (selective signals for balance)

  Section below the pontine level   Decerebration rigidity

Page 16: Assoc. Prof. Sinan Canan - aybu.edu.tr · Motor Cortex Primary motor cortex Primary source for the motor commands to lower motor neurons. Somatotopical organization “Motor homunculus”

Lesions of the motor system

 Primary motor cortex lesion  Paralysis…

 Premotor area; Caudate nucleus lesions  Loss of voluntary control of fine movements

 Widespread “stroke”  Overexitability and spasticity

Page 17: Assoc. Prof. Sinan Canan - aybu.edu.tr · Motor Cortex Primary motor cortex Primary source for the motor commands to lower motor neurons. Somatotopical organization “Motor homunculus”

The End...