DECEMBER 1992 VOL 51 NO 12

IlM\1~11MLCNI

510270000

Reviews

Notes and news

Book review

Extended reports

Concise reports

Case report

Dispatch

Letters to the editor

Author index

Subject index

.- i .- -, `.1S- I i

, r.-,

I'_-

4- I t,,t4."4AA Z!, P% ---M.~~~oAtM t, T r.J^~st,

;' ---ie)aptA.-

135237Annals of the

artTMATICY

RHEe AQFJ

1287 Magnetic resonance imaging in rheumatology Christine WHeron

1292 Epidemiology of systemic lupus erythematosus Neil Hopkinson

1295 Forthcoming events

1295 Rheumatic diseases

1296 Systemic and mucosal antibodies to klebsiella in patients with ankylosing spondylitis and Crohn's diseaseS O'Mahony, N Anderson, G Nuki, et al

1301 Autoantibodies in chronic arthritis of childhood: relations with each other and with histocompatibilityantigens PeterN Malleson, Marinda YFung, Ross E Petty, et al

1307 IgG and IgM anti-snRNP reactivity in sequentially obtained serum samples from patients with connectivetissue diseases UlfNyman, Ingrid Lundberg, Eva Hedfors, et al

1313 Clinical associations of IgG antibodies to the ribonucleoprotein p67 polypeptide in patients with systemiclupus erythematosusJ Vencovsky, D G Williams, M Field, et al

1318 Continuation of long term treatment with hydroxychloroquine in systemic lupus erythematosus andrheumatoid arthritis E F Morand, P I McCloud, G 0 Littlejohn

1322 What is the contribution of occupational environmental factors to the occurrence of scleroderma in men?AlanJ Silman, StevenJones

1325 Work related upper limb disorder: the relationship between pain, cumulative load, disability, andpsychological factors P S Helliwell, D B Mumford,J E Smeathers, et al

1330 Methotrexate treatment of rheumatoid arthritis: is a fortnightly maintenance schedule enough?Moshe Tishler, Dan Caspi, Michael Yaron

1332 Long term prognosis in yersinia arthritis: clinical and serological findingsJ D Herrlinger,J-UAsmussen1335 Giant cell tumours in mandible and spine: a rare complication of Paget's disease of boneM Bhambhani,

B GH Lamberty,M R Clements, et al

1338 Coexisting HLA-B27 positive spondyloarthritis and polyarteritis nodosaM A Sattar

1340 From the Pacific Basin Peter Brooks

1342 IgG rheumatoid factor synthesis in synovial fluid S Visvanathan, P W Robertson, V Bertouch

1342 Postpartum autologous plasma transfusion: effect on RA CraigD Scoville

1343 Colchicine myoneuropathy and renal dysfunction* StevenA Older, DavidS Finbloom,GholamH Pezeshkpour

1344 Polyarteritis nodosa and acute interstitial pneumonia TMatsumoto,M Okada, N Kuwabara, et al

1345 Radiographic assessment of the knee joint in OA BruceM Rothschild; Cyrus Cooper,Jfohn Kirwan,Paul Dieppe

1346

1360

BMJ PUBLISHING GROUP

if "'?

e,-,. f I i-

on Novem

ber 26, 2020 by guest. Protected by copyright.

http://ard.bmj.com

/A

nn Rheum

Dis: first published as on 1 D

ecember 1992. D

ownloaded from

VOLUME 51 CONTENTS

No 1 JANUARY 1992 Journal summary1 Editor's resume

Leader4 Mechanical stimulus to bone A E Goodship

Notes and news7 4th European congress on back pain 0 7th APLAR congress of rheumatology 0 Low back pain * System science

in health care * International Society for Rheumatic Therapy * Inflammation Research Association * EULARepidemiology committee 0 3rd international lupus conference

Scientific papers8 Increased DNA strand breaks in mononuclear cells from patients with rheumatoid arthritis L L Bhusate,KE Herbert, D L Scott, et al

13 Morphological evidence that activated polymorphs circulate in the peripheral blood of patients with rheumatoidarthritis DA McCarthy,J Bernhagen, MJ Taylor, et al

19 Human neutrophil activating peptide/interleukin 8 acts as an autoantigen in rheumatoid arthritis P Peichl,M Ceska,HBroell, et al

23 HLA-D region genes and rheumatoid arthritis (RA): importance of DR and DQ genes in conferring susceptibilityto RA Dharam P Singal, Donna Green, Barbara Reid, et al

29 Presence of paf-acether in rheumatic diseases P Hilliquin, cJ Menkes, S Laoussadi, et al32 Treatment of early rheumatoid arthritis with rifampicin N L Cox, M V Prowse, M C Maddison, et al35 Muscle strength, endurance, and aerobic capacity in rheumatoid arthritis: a comparative study with healthy subjects

Charlotte Ekdahl, Gabriella Broman41 Idiopathic myositis: a rheumatological view Michael R Ehrenstein, Michael L Snaith, DavidA Isenberg45 A longterm immunological studyofchildhoodonset systemiclupuserythematosus Cheng-Kai Ting, Kue-HsiungHsieh52 Differences in HLA antigens between patients with mixed connective tissue disease and systemic lupus erythematosus

Pekka Ruuska, Risto Hameenkorpi, Sinikka Forsberg, et al56 Peripheral vascular disease in patients with systemic lupus erythematosus Joanne McDonald, Jacqueline Stewart,

MurrayB Urowitz, et al61 Antibodies to histones in systemic lupus erythematosus: prevalence, specificity, and relationship to clinical and

laboratory features Michael G Cohen, KMichael Pollard,Jfohn Webb67 Different capabilities of monocytes from patients with systemic lupus erythematosus and rheumatoid arthritis to

induce glycosylation alterations of acute phase proteins in vitro Andrzej Mackiewicz, Magdalena Sobieska,Malgorzata Kapcintska, et al

73 The cervical spine in patients with psoriatic arthritis: a clinical, radiological and immunogenetic studyCarlo Salvarani, Pierluigi Macchioni, Tiziana Cremonesi, et al

78 Interplay between environmental factors, articular involvement, and HLA-B27 in patients with psoriatic arthritisR Scarpa, A Del Puente, C di Girolamo, et al

80 Radiographic assessment of the knee joint in osteoarthritis C Cooper,JI Cushnaghan,J R Kirzvan, et al83 Immune complexes in ankylosing spondylitis I L MacLean,J R Archer, M ID Cawley, et al87 General joint hypermobility and temporomandibular joint derangement in adolescents Lilian Westling, Agneta

Mattiasson91 Long term follow up of SHR rats with experimental yersinia associated arthritis R Merilahti-Palo,

C Gripenberg-Lerche, K-0 Soderstrom, et al97 Does reduced erythrocyte C3b receptor (CR1) activity contribute to the pathogenesis of yersinia triggered reactive

arthritis? Riitta Lahesmaa, Erkki Eerola, Auli Toivanen101 Relation between creatinine and uric acid excretion Y Nishida103 Computerised infrared thermography and isotopic bone scanning in tennis elbow Dale Thomas, Georgia Siahamis,

Millicent Marion, et al108 Lack of association between fibromyalgia and sleep apnoea syndrome Bonifacio Alvarez Lario,J7oaquin Teran,

Jose L Alonso, et al112 Effect of sodium aurothiomalate on carrageenan induced inflammation of the air pouch in mice YM Sin, M K Wong

Case reports117 Organic brain syndrome with psychosis as an initial manifestation of systemic lupus erythematosus in an elderly

womanM E Mavrikakis, L G Antoniades, B Germanides, et al

120 Systemic lupus erythematosus complicated by tricuspid stenosis and regurgitation: successful treatment by valvetransplantation DianeE Ames, RonaldA Asherson, John D Coltart, et al

123 Selective IgA deficiency associated with glomerulonephritis and oligoarthritis J P Camilleri, RH Moore,DF R Griffiths, et al

Rapid report126 Adhesion of rheumatoid peripheral blood and synovial fluid mononuclear cells to high endothelial venules of

gut mucosa A Kadioglu, P Sheldon

Now and then128 Efficacy of cod liver oil as an adjunct to non-steroidal anti-inflammatory drug treatment in the management of

osteoarthritis in general practice Trevor Stammers, Bonnie Sibbald, Paul FreelingReviews

130 Osteoporosis: whose problem is it? Anthony D Woolf134 Attributing psychopathology to systemic lupus erythematosus: some methodological considerations Grant L Iverson,

LanceM McCracken

Hypothesis136 Slow viruses and the immune system in the pathogenesis of local tissue damage in Sjogren's syndrome

GeorgeK Papadopoulos, HaralamposM Moutsopoulos

Letters to the editor139 Severe haemorrhagic gastric erosion associated with Sjogren's syndrome Yoshihisa Ogata, Mikio Kimura,

Satoshi Kimura, et al140 Disease activity score DesisreM FM van der Heijde, Martin A Van't Hof, Piet L CM Van Riel, et al140 Salmonella peritonitis and splenic abscess in a patient with systemic lupus erythematosus M Hammoudeh,

A Rahim Siam

on Novem

ber 26, 2020 by guest. Protected by copyright.

http://ard.bmj.com

/A

nn Rheum

Dis: first published as on 1 D

ecember 1992. D

ownloaded from

140 Prophylaxis against non-steroidal induced upper gastrointestinal side effects R P Knill Jones; SanfordH Roth;G C Fenn;M S Irani; R M Bernstein; I BarrisonEncore

144 A look at recent publications

No 2 FEBRUARY 1992 Journal summary145 Editor's resume

Leader147 The antiphospholipid syndrome: a syndrome in evolution R A Asherson, R Cervera

Notes and news151 Treatment of rheumatic diseases 0 Immunopathology of the skin * XVIII congress of rheumatology * Open day

at Bath, November 1991 0 Sixth Mediterranean congress of rheumatology * Science and practice ofrheumatology * Pressure sores: a universal problemScientific papers

152 Fasting lipids and anticardiolipin antibodies as risk factors for vascular disease in systemic lupus erythematosusAJ MacGregor, VB Dhillon, A Binder, et al

156 Cardiac disease in systemic lupus erythematosus: prospective study of 70 patients Ricard Cervera,3Josep Font,Carles Pare, et al

160 Reassessing the status of antiphospholipid syndrome in systemic lupus erythematosus Jodo L Vianna, HansJ Haga,Poonam Tripathi, et al

162 Effect of antibodies to double stranded DNA, purified from serum samples of patients with active systemic lupuserythematosus, on the glomerular mesangial cells Chang-Youh Tsai, Tsai-Hung Wu, Kuang-Hui Sun, et al

168 Increased excretion of soluble interleukin 2 receptors and free light chain immunoglobulins in the urine of patientswith active lupus nephritis Chang-Youh Tsai, Tsai-Hung Wu, Kuang-Hui Sun, et al

173 Coexistent rheumatoid arthritis and systemic lupus erythematosus: clinical, serological, and phenotypic featuresCarolineA Brand, MerrillJ Rowley, Brian D Tait, et al

177 Validity of single variables and composite indices for measuring disease activity in rheumatoid arthritisDeisireeM FM van der Heijde, Martin A van't Hof, Piet L CM van Riel, et al

182 Contribution of inherited factors to rheumatoid arthritis CM Deighton,I Wentzel, G Cavanagh, et al186 Prevalence of chronic arthritis in four geographical areas of the Scottish Highlands MM Steven195 Survey of satisfaction with care in a rheumatology outpatient clinic J Hill, HA Bird, R Hopkins, et al198 Production and modulation of interleukin 6 synthesis by synoviocytes derived from patients with arthritic disease

James T Rosenbaum, Regina Cugnini, David C Tara, et al203 Influence of dichloromethylene bisphosphonate on the in vitro phagocytosis of hydroxyapatite particles by rat

peritoneal exudate cells: an electron microscopic and chemiluminescence study PM Hyvonen, MJI Kowolik210 Experimental arthritis in rats induced by intra-articular injection of IgE aggregates: evidence for arthritogenic role of

complexed IgE L S de Clerck, NJ Struyf, CH Bridts, et al214 Methylprednisolone acetate induced release of cartilage proteoglycans: determination by high performance liquid

chromatography Herkko Saari, Riitta-Mari Tulamo, Yjo TKonttinen, et al220 Differential metabolism of 25-hydroxyvitamin D3 by cultured synovial fluid macrophages and fibroblast-like cells

from patients with arthritis M E Hayes, D Bayley, P Still, et al227 Myocardial dysfunction in ankylosing spondylitis Brian A Gould, John Turner, David H Keeling, et al233 IgA antibody response to klebsiella in ankylosing spondylitis measured by immunoblotting F Shodjai-Moradi,

A Ebringer, IAbuliadayel238 A double blind, multicentre, placebo controlled trial of lornoxicam in patients with osteoarthritis of the hip and knee

HBerry, HA Bird, C Black, etal243 Evaluation of a method for clinically assessing osteoarthritis of the knee Adrian3Jones, Neil Hopkinson,

Martin Pattrick, et al246 Association of Wegener's granulomatosis with HLA antigens and other genetic markers S S Papiha, G E Murty,

A Ad'Hia, et al249 White blood cell activation in Raynaud's phenomenon of systemic sclerosis and vibration induced white finger

syndrome CS Lau, A O'Dowd,JJ F Belch253 Clinically silent infections in patients with oligoarthritis: results of a prospective study Cornelia M Weyand,

_JorgJ' Goronzy259 Diuretic induced gout: a multifactorial condition J TScott, CS Higgens262 Comparison of two yttrium-90 regimens in inflammatory and osteoarthropathies R Will, B Laing,J Edelman, et al266 Development and validation of a computer program using Bayes's theorem to support diagnosis of rheumatic disorders

HJ Bemelot Moens, J K van der KorstCase reports

272 Successful reintroduction of methotrexate after pneumonitis in two patients with rheumatoid arthritis NJ7 Cook,GJ Carroll

275 Sulphasalazine induced hepatitis in juvenile rheumatoid arthritis D Caspi, D Fuchs, M Yaron277 Mastocytosis and Sjogren's syndrome DJ Bac,M van Marwijk Kooy279 Cardiac tamponade as an initial manifestation of systemic lupus erythematosus in early childhood Sanjeev Gulati,

Lata KumarDispatch

281 From Belgium Jan DequekerNow and then

283 W S C Copeman: his importance in contemporary medicine Lord Porritt, F Dudley HartReview

286 A brief overview of the pathogenesis of scleroderma (systemic sclerosis) E Carzile LeRoy

No 3 MARCH 1992 Journal summary289 Editor's resume

Leader292 Articular tissue grafts George Bentley

Notes and news297 Degenerative joint disease * Nurofen pain relief project travel awards * Outcome measures in rheumatoid arthritis

clinical trials 0 ARC congress bursaries and educational travel awards * Hypertrophic osteoarthropathy 0Computer assisted diagnosis of rheumatic disorders 0 Pressure sores: a universal problem * Spring symposiumon back pain

on Novem

ber 26, 2020 by guest. Protected by copyright.

http://ard.bmj.com

/A

nn Rheum

Dis: first published as on 1 D

ecember 1992. D

ownloaded from

Scientific papers298 Food intolerance in rheumatoid arthritis. I. A double blind, controlled trial of the clinical effects of elimination of milk

allergens and azo dyes M A FJ van de Laar,JK van der Korst303 Food intolerance in rheumatoid arthritis. II. Clinical and histological aspects M A FJ van de Laar, M Aalbers,

F G Bruins, et al307 Leucocyte integrin and CR1 expression on peripheral blood leucocytes of patients with rheumatoid arthritis

D McCarthy, MJ Taylor, J Bernhagen, et al313 Localisation and characterisation of substance P binding to human synovial tissue in rheumatoid arthritis

D A Walsh, P I Mapp, J Wharton, et al318 Increased prevalence of poor sulphoxidation in patients with rheumatoid arthritis: effect of changes in the acute phase

response and second line drug treatment Paul Emery, Helen Bradley, Andrew Gough, et al321 Inhibition of neutrophil oxidant secretion by D-penicillamine: scavenging of H202 and HOCI Martinj Ledson,

Roger C Bucknall, Steven W Edwards326 Skin rashes and stomatitis due to parenteral treatment of rheumatoid arthritis with sodium aurothiomalate

A Svensson,3J Theander330 A new method for the radiological assessment of vertebral squaring in ankylosing spondylitis Stuart H Ralston,

GrantDK Urquhart, Maciej Brzeski, et al334 Antibody to a 63 kilodalton insect protein in ankylosing spondylitis S R Brand,J Worthington, D P McIntosh, et al340 Increasing age at presentation for patients with ankylosing spondylitis R Will, A Calin,J Kirwan343 Assessment of pain in patients with juvenile rheumatoid arthritis: relation between pain intensity and degree of joint

inflammation Norman T Ilowite, Gary A Walco, Rubem Pochaczevsky347 Disseminated intravascular coagulation with renal and liver damage as the predominant manifestations of recurrent

relapses in systemic juvenile rheumatoid arthritis D Schwartz, M Averbuch, A Pines, et al350 Antiperinuclear factor in juvenile rheumatoid arthritis Gideon Nesher, Terry L Moore, Michael W Grisanti, et al353 Prospective study of fluctuations of lupus anticoagulant activity and anticardiolipin antibody titre in patients with

systemic lupus erythematosus Henkj Out, Maria van Vliet, Philip G de Groot, et al358 Patients with systemic lupus erythematosus and Jaccoud's arthropathy: a clinical subset with an increased C reactive

protein response? P E Spronk, EJ terBorg, CGM Kallenberg362 Spontaneous increase of transforming growth factor 01 production by bronchoalveolar mononuclear cells of patients

with systemic autoimmune disease affecting the lung Y Deguchi366 Changing profile of joint disorders with age: findings from a postal survey of the population of Calderdale,

West Yorkshire, United Kingdom Elizabeth M Badley, Alan Tennant372 Sternoclavicular joint disease in psoriatic arthritis E Taccari, A Spadaro, V Riccieri, et al375 Genetic control of the renal clearance of urate: a study of twins B TEmmerson, S L Nagel, D L Duffy, et al378 Staphylococcal infections in childhood dermatomyositis-association with the development of calcinosis, raised

IgE concentrations and granulocyte chemotactic defect Ellen C Moore, Flossie Cohen, Steven D Douglas, et al384 Microalbuminuria in systemic sclerosis A Dawnay, A G Mc T Wilson, E Lamb, et al389 Damage to the endothelium in Sjogren's syndrome: lack of correlation with antinuclear antibody titre and presence of

antibodies to SSA or SSB autoantigens A D Blann, A C Wainwright, P Emery391 Analgesic effect of indomethacin shown using the nociceptive flexion reflex in humans R Guieu, 0 Blin,

J Pouget, et al

Case reports394 Abdominal pain with free peritoneal fluid detected by ultrasonography as a presenting manifestation of acute

rheumatic fever E Picard, A Gedalia, P Benmeir, et al396 Thrombotic thrombocytopenic purpura preceding systemic lupus erythematosus Carmen Pilar Simeon-Aznar,

Rafael Cuenca-Luque, Vicente Fonollosa-Pla, et al399 Immunoadsorbent plasmapheresis for a patient with antiphospholipid syndrome during pregnancy S Kobayashi,

N Tamura, H Tsuda, et al402 Infectious arthritis in patients with rheumatoid arthritis Lourdes Mateo Soria, Joan Miquel Nolla Sole,

Antonio Rozadilla Sacanell, et al404 Brucellosis induced avascular necrosis of the femoral head in a 7 year old child Abraham Gedalia, Charles Howard,

Menachem Einhorn407 Sequential follow up observations of a patient with rubella associated persistent arthritis D K Ford, G D Reid,

AJ Tingle, et al411 Rat bite fever without the bite J N Fordham, E McKay-Ferguson, A Davies, et al413 Early aortic valve cusp rupture in relapsing polychondritis DA S Marshall, R Jackson, A P Rae, et al416 Bone abnormalities and severe arthritis in pachydermoperiostosis R G Cooper, AJ Freemont, M Riley, et al

Dispatch420 From the Pacific Basin Peter Brooks

Now and then422 Effect of penicillamine on the titre of rheumatoid factor: a historical perspective Evelyn V Hess, Morris Ziff

Review424 Slow drugs: slow progress? Use of slow acting antirheumatic drugs (SAARDs) in rheumatoid arthritis HA Capell,

M BrzeskiLetters to the editor

430 Polymyalgia rheumatica: report of a case with severe synovitis (synovial cysts) LuisH Silveira, LuistJJara,Pindaro Martinez-Osuna, et al

431 Bronchial hyperresponsiveness to methacholine in primary Sjogren's syndrome R La Corte, G Bajocchi, F Trotta,B Gudbjornsson, H Hedenstrom, G StdlenheimEncore

432 A look at recent publications

No 4 APRIL 1992 Leaders433 From Truro to Nottingham Michael Doherty434 ' "The time has come" the walrus said . . .' Adrian Jones, Michael Doherty

Notes and news436 Ciba-Geigy ILAR rheumatology prize 1993 0 Roche rheumatology award * The Metro A Ogryzlo international

fellowship * Pain and disability: can we prevent them?Scientific papers

437 Increased risk of cancer in patients with systemic lupus erythematosus Tom Pettersson, Eero Pukkala,Lyly Teppo, et al

on Novem

ber 26, 2020 by guest. Protected by copyright.

http://ard.bmj.com

/A

nn Rheum

Dis: first published as on 1 D

ecember 1992. D

ownloaded from

440 Upregulation of insulin-like growth factor I gene expression in the lesions of osteoarthritic human articular cartilageJames F S Middleton,JennyA Tyler

448 Effects of tiaprofenic acid (Surgam) on cartilage proteoglycans in the rabbit joint immobilisation modelIsabelle Meyer-Carrive, Peter Ghosh

456 Sulphydryl reactivity of the HLA-B27 epitope: accessibility of the free cysteine studied by flow cytometryLachy MacLean, Marion Macey, Mark Lowdell, et al

461 Prospective trial comparing the use of sulphasalazine and auranofin as second line drugs in patients with rheumatoidarthritis D Porter, R Madhok, JA Hunter, et al

465 Increase in neutrophil Fcy receptor I expression following interferon gamma treatment in rheumatoid arthritisNJ Goulding, SM Knight,I L Godolphin, et al

469 Structured approach to the investigation of anaemia in patients with rheumatoid arthritis A Doube,M Davis,J G Smith, et al

473 Influence of the severity of rheumatoid arthritis on sex differences in Health Assessment Questionnaire scoresCM Deighton, D Surtees, DJ Walker

476 Production of angiotensin converting enzyme by rheumatoid synovial membrane Douglas Veale, Ghada Yanni,Barry Bresnihan, et al

481 Occurrence of (E)-4-hydroxy-2-nonenal in plasma and synovial fluid of patients with rheumatoid arthritis andosteoarthritis M L Selley, DJ Bourne, M R Bartlett, et al

485 Tests on hypotheses about osteoarthritis and hip joints N YP Afoke, P D Byers, WC Hutton489 Antibodies to protein P in systemic lupus erythematosus L S Teh, A E Bedwell, D A Isenberg, et al495 Antiphospholipid antibodies and HLA associations in primary Sjogren's syndrome Ronald A Asherson,

Hong-Ming Fei, Henrique L Staub, et al499 Measurement of whole unstimulated salivary flow in the diagnosis of Siogren's syndrome PaulM Speight,

ArvindKaul, RichardD Melsom503 02 Microglobulin in tear fluid from patients with primary Sjogren's syndrome HM Markusse,J C Huysen,

EJ Nieuwenhuys, et al506 Nervous system disease, immunological features, and HLA phenotype in Sjogren's syndrome Aki Hietaharju,

Markku Korpela,Jorma Ilonen, et al510 Influence of decontamination on induction of arthritis in Lewis rats by cell wall fragments of Eubacterium aerofaciens.

Arthropathic properties of indigenous anaerobic bacteria Jeanette Kool, AntonJ Severijnen, Ina S Klasen, et al516 Effect of iron complexes on adjuvant arthritis in rats AJ Dabbagh, DR Blake, CJ Momrs522 Predictive value of synovial fluid-analysis in juvenile chronic arthritis L Punzi, R Ramonda, S Glorioso, et al525 Epidemiology of rheumatic diseases in rural and urban populations in Indonesia: a World Health Organisation

International League Against Rheumatism COPCORD study, stage I, phase 2 John Darmawan, HansA Valkenburg,Kenneth D Muirden, et al

529 Adult onset Still's disease: clinical experience with 18 patients over 15 years in northern India P Bambery,RJ Thomas, H S Malhotra, et al

533 Intra-articular rheumatoid nodules and triggering of the knee joint Z Tak-Diamant, FJJ Hooning van Duyvenbode,F Eulderink, et alCase reports

536 Bezafibrate induced rhabdomyolysis Eduardo Kanterewicz, Raimon Sanmarti, Jaume Riba, et al539 Condensing osteitis of the clavicle: magnetic resonance imaging as an adjunct method for differential diagnosis

MarianneA C Vierboom, Julia DJ Steinberg, EduardL Mooyaart, et al542 Articular manifestations of Scheie's syndrome Eric Hamilton, Pauline Pitt544 Mixed connective tissue disease associated with autoimmune hepatitis and thyroiditis M Tomfii, V Ferlan-Marolt,

TKveder, et al547 Neurogenic bladder due to peripheral neuropathy and a visual disturbance in an elderly man with systemic lupus

erythematosus Takashi Wada, Hitoshi Yokoyama, Kenzo Ikeda, et al550 Cerebral occlusive vasculopathy in systemic lupus erythematosus and speculation on the part played by complement

Ali Hammad, Yoshiaki Tsukada, Nelson Torre553 Detection of cytomegalovirus antigens in phagocytosed serum complexes from a patient with rheumatoid arthritis,

vasculitis, peripheral neuropathy, cutaneous ulceration, and digital gangrene J N McCormick, D Wojtacha,E Edmond

556 Polyarthritis as the presenting symptom of the occurrence and recurrence of a laryngeal carcinoma F Eggelmeijer,JD Macfarlane

558 Palmoplantar pustulotic arthro-osteitis of the peripheral joints with no stemocostoclavicular lesions Michito Takagi,Jyunji Oda, Nobuyuki Tsuzuki, et alNow and then

561 Siebrandus Sixtius: evidence of rheumatoid arthritis of the robust reaction type in a seventeenth century Dutchpriest J DequekerDispatch

563 From Eastern Europe C P BalintReview

565 The cytoskeleton and its importance as a mediator of inflammation KR Rogers, CJ Morris, D R BlakeLetters to the editor

572 Normal production of neutrophil activating peptide l/interleukin 8 in monocytes from subjects with previous yersiniatriggered reactive arthritis H Repo,M Ristola, Mariatta Leirisalo-Repo, et al

573 Hand radiography: an indicator of upper cervical disease in rheumatoid arthritis M Nafiz Akman, Gulay Dincer573 Positive antinuclear antibodies in malignancies Margit Zuber574 Conjunctival ulceration in Behqet's syndrome Ignazio Olivieri, Federica Genovesi-Ebert, Gino Signorini, et al

Acknowledgments576 To assessors in 1991

No 5 MAY 1992 Leader577 Immunotherapy of rheumatoid arthritis R A Watts,J_ D Isaacs

Notes and news580 5th French annual congress of rheumatology * Rheumatology Aid to Eastern Europe (RAEE) * Second intensive

course on applied epidemiology * Advanced course in rheumatologyBook review

580 A Concise International History of Rheumatology and Rehabilitation: Friends and FoesScientific papers

581 Predictors of disability in a longitudinal sample of patients with rheumatoid arthritis J Paul Leigh, James F Fries

on Novem

ber 26, 2020 by guest. Protected by copyright.

http://ard.bmj.com

/A

nn Rheum

Dis: first published as on 1 D

ecember 1992. D

ownloaded from

588 Rheumatoid arthritis in twins: a study of aetiopathogenesis based on the Australian Twin Registry N Bellamy,D Duffy, N Martin, et al

594 Impairment of neutrophil Fcy receptor mediated transmembrane signalling in active rheumatoid arthritisNicolasj Goulding, PaulM Guyre

600 Controlled trial of methotrexate versus 10-deazaaminopterin in the treatment of rheumatoid arthritisGraciela S Alarcon, Oswaldo Castaineda,M Gopal Nair, et al

604 Increased incidence of urinary tract infection in patients with rheumatoid arthritis and secondary Sjogren's syndromeMoshe Tishler, Dan Caspi, Yehoshua Almog, et al

607 Siogren's syndrome: a stepwise approach to the use of diagnostic tests Joaquim Coll, Miquel Porta,Juan Rubies-Prat, et al

611 Diversity and pattern of inheritance of autoantibodies in families with multiple cases of systemic lupus erythematosusYehuda Shoenfeld, Hanoch Slor, Sheike Shafrir, et al

619 Risk factors in the pregnancy of patients with systemic lupus erythematosus: association of hypocomplementaemiawith poor prognosis S Shibata, TSasaki, YHirabayashi, etal

624 Chromosome studies in systemic sclerosis with consideration of antibodies to topoisomerase I Gregoryj Tsay,Joung-LiangLan, Shuan-Yow Li

627 Outcome of patients with systemic rheumatic disease admitted to medical intensive care units Bertrand Godeau,Azzedine Boudjadja, Jean-Franfois Dhainaut, et al

632 Inhibition by prostaglandin El and E2 of 1,25-dihydroxyvitamin D3 synthesis by synovial fluid macrophages fromarthritic joints ME Hayes, A Rai, R G Cooper, et al

638 Interleukin la and 0i production by cells isolated from membranes around aseptically loose total joint replacementsCarole I Westacott, Graham Taylor, Roger Atkins, et al

643 Inhibition of proteoglycan synthesis by transforming growth factor Ds in anatomically intact articular cartilage ofmurine patellae PeterM van derKraan, Elly L Vitters, WimB van den Berg

648 Urinary excretion of pyridinium crosslinks of collagen in patients with osteoporosis and the effects of bone fractureA M McLaren, L D Hordon, HA Bird, et al

652 Echocardiographic abnormalities in ankylosing spondylitis TW O'Neill, G King, IM Graham, et al655 Chronic otitis media: a new extra-articular manifestation in ankylosing spondylitis? A E Camilleri, I R C Swan,

E Murphy, et al658 Sternocostoclavicular hyperostosis: its progression and radiological features. A study of 12 cases Peter Fnrtz,

Gerhard Baldauf, Hans-Joachim Wilke, et al665 Role of technetium-99m diphosphonate and gallium-67 citrate bone scanning in the early diagnosis of infectious

spondylodiscitis. A comparative study Joan Miquel Nolla-Sole, Lourdes Mateo-Soria, Antonio Rozadilla-Sacanell, et al668 Heredofamilial deficiency of monocyte esterase in patients with rheumatoid arthritis A L Bell, GM Markey,

M D McCaigue, et al671 Antiphospholipid antibodies in homozygous sickle cell disease Karel De Ceulaer, MuntherA Khamashta,

E Nigel Harris, et al673 HTLV-I associated arthritis: characteristics ofan HTLV-I virus infected T cell line from synovial fluid

Katsumi Eguchi, Tatsufumi Nakamura, Masanobu Mine, et al678 Polyarteritis associated with Yersinia enterocolitica infection Kevin Pile, Tery Kwong,Judith Fryer, et al681 Monarthritis: an unusual presentation of renal cell carcinoma KK Chakravarty,M Webley683 Evaluation of serum ferritin as a marker for adult Still's disease activity Michael Schwarz-Eywill, Bernhard Heilig,

HeidiBauer, et al686 Acute aortic insufficiency in a patient with presumed Reiter's syndrome Patricia Misukiewicz, Richard W Carlson,

Laurie Rowan, et al.688 An infiltrating rheumatoid nodule? A H Isdale, P S Helliwell

Review690 Fungal arthritis Marta L Cuellar, LuisH Silveira, Luis R Espinoza

Hypothesis698 Local immune responses in certain extra-articular manifestations of rheumatoid arthritis James THalla,

Ralph E Schrohenloher, WilliamJI KoopmanDispatch

702 From Britain, 1991 V WrightLetters to the editor

704 Symptomatic salicylate ototoxicity: a useful indicator of serum salicylate concentration? AJ Taggart704 Plasma endothelin-1 concentrations in polyarteritis nodosa Patrice Cacoub, Jean Charles Piette,

Bertrand Wechsler, et al704 Septic arthritis complicating hip osteoarthritis J M Nolla-Soh, L Matteo-Soria, A Rozadilla-Sacanell, et al

Leader705 The heart in ankylosing spondylitis TW O'Neill, B Bresnihan

Scientific papers707 Inhibition of astrocyte proliferation and binding to brain tissue of anticardiolipin antibodies purified from lupus serum

Kuang-Hui Sun, Wu-Tse Liu, Chang-Youh Tsai, et al713 Autoantibodies to T and B cell lines detected in serum samples from patients with systemic lupus erythematosus

with lymphopenia and hypocomplementaemia Masaaki Noguchi, Masao Iwamori, Takao Hirano, et al717 Rash in systemic lupus erythematosus: prevalence and relation to cutaneous and non-cutaneous disease manifestations

ArjehJ Wysenbeek, Daniele Guedj, Mirit Amit, et al720 Immunofluorescence microscopy of healthy skin from patients with systemic lupus erythematosus: more than just the

lupus band PJ7 Velthuis, L Kater, I van der Tweel, et al726 Effects of ultraviolet irradiation on natural killer cell function in systemic lupus erythematosus Ola Nived,

IngridJohansson, Gunnar Sturfelt731 Determination of cytokines in synovial fluids: correlation with diagnosis and histomorphological characteristics of

synovial tissue P Kahle, G Saal, K Schaudt, et al735 Localisation of fibronectin mRNA in the rheumatoidsynovium by in situ hybridisation HA Waller,MG Butler,

J GB McClean, etal741 Constitutive production of angiotensin converting enzyme from rheumatoid nodule cells under serum free conditions

Makoto Goto, Minoru Sasano, Michio Fuzisawa, etal743 Antikeratin antibodies: diagnostic and prognostic markers for early rheumatoid arthritis Leena Paimela,

Marianne Gripenberg, Pekka Kurki, etal747 Response of anaemia in rheumatoid arthritis to treatment with subcutaneous recombinant human erythropoietin

Bjorn Gudbjornsson, Roger Hallgren, Leif Wide, et al753 Anaemia of chronic disease in rheumatoid arthritis: effect of the blunted response to erythropoietin and of interleukin 1

production by marrow macrophages M A Smith, SM Knight, PJ7 Maddison, et al

No 6 JUNE 1992

on Novem

ber 26, 2020 by guest. Protected by copyright.

http://ard.bmj.com

/A

nn Rheum

Dis: first published as on 1 D

ecember 1992. D

ownloaded from

758 Double blind, placebo controlled study of metronidazole as a disease modifying agent in the treatment of rheumatoidarthritis DA SMarshall,J A Hunter, HA Capell

761 Intranasal calcitonin for the prevention of bone erosion and bone loss in rheumatoid arthritis A Sileghem, P Guesens,J Dequeker

765 Opinions of patients with rheumatoid arthritis about their own functional capacity: how valid is it? J W GJacobs,F GJ Oosterveld, N Deuxbouts, et al

769 Primary Sjogren's syndrome with antibodies to HTLV-I: clinical and laboratory features Katsumi Eguchi,Naoki Matsuoka, Hiroaki Ida, et al

777 Follow up study of labial salivary gland lesions in primary Sjogren's syndrome J P Leroy, YL Pennec,Catherine Soulier, et al

781 Soluble interleukin 2 receptors in patients with polymyositis/dermatomyositis Yoshiaki Tokano, Yoshinori Kanai,Hiroshi Hashimoto, et al

783 Absence of autoantibodies to peptides shared by HLA-B27.5 and Klebsiella pneumoniae nitrogenase in serum samplesfrom HLA-B27 positive patients with ankylosing spondylitis and Reiter's syndrome D D de Vries, A J Dekker-Saeys,E Gyodi, et al

790 Increased levels of serum IgA as IgAI monomers in ankylosing spondylitis Hakim Hocini, Sylvio Iscaki,CharifBenlahrache, et al

793 Joint hypermobility in adults referred to rheumatology clinics AlanJBridges, ElaineSmith,John Reid797 Aberrant cytokine production from tenosynovium in dialysis associated amyloidosis Nobuyuki Miyasaka,

Kazuto Sato, Yuri Kitano, et alCase reports

803 Possible induction of systemic lupus erythematosus by human parvovirus A P Cope, A Jones,M Brozovic, et al805 Histiocytic necrotising lymphadenitis in systemic lupus erythematosus M D Litwin, B Kirkham,

DR F Henderson, et al808 Primary Sjogren's syndrome preceding the presentation of systemic lupus erythematosus as a benign intracranial

hypertension syndrome X Chevalier,M de Bandt, P Bourgeois, et al810 Knee contractures as the presenting manifestation of scleroderma Gwen Kane-Wanger, Barbara E Ostrov,

Bruce Freundlich812 Granulomatous lipophagic panniculitis and temporal arteritis in a patient with cryptogenic chronic active hepatitis

J E Naschitz, D Yeshurun,JI Barth, et al815 Multicentric reticulohistiocytosis with arthritis and cardiac infiltration: regression following treatment for underlying

malignancy CM Lambert, G NukiDispatch

818 From Spain E LienceNow and then

820 Controlled trial of balneotherapy in treatment of low back pain K Konrad, T Tatrai, A Hunka, et alReviews

823 Bone mass in osteoarthritis L D Hordon, V Wright,M A Smith826 Bone mass in patients with rheumatoid arthritis RolandFJM Laan, Piet LCM van Riel, Levinus B A van de Putte

Leader833 Can man's best friend provide clues to the aetiology of systemic lupus erythematosus? RJ Powell, D R EH7ones

Scientific papers835 Effect of education, occupation and some lifestyle factors on common rheumatic complaints in a Swedish group aged

50-70 years LJacobsson, F Lindgarde, R Manthorpe, et al844 Radiographic patterns of osteoarthritis of the knee joint in the community: the importance of the patellofemoral joint

TE McAlindon, S Snow, C Cooper, et al850 Reduction of the concentration and total amount of keratan sulphate in synovial fluid from patients with osteoarthritis

during treatment with piroxicam GJ Carro!!, MC Bell, B A Laing, etal855 Ankylosing spondylitis and HLA-B27: restriction fragment length polymorphism and sequencing of an HLA-B27

allele from a patient with ankylosing spondylitis ColleenM Higgins, Torben Lund, Michael E Shipley, et al863 Population study of the importance of rheumatoid factor isotypes in adults TJonsson, J Thorsteinsson,

A Kolbeinsson, et al869 Pathogenic importance of fibronectin in the superficial region of articular cartilage as a local factor for the induction of

pannus extension on rheumatoid articular cartilage S Shiozawa, R Yoshihara, YKuroki, et al874 Predictive value of synovial fluid analysis in estimating the efficacy of intra-articular corticosteroid injections in

patients with rheumatoid arthritis Reijo Luukkainen, Markku Hakala, Esko Sajanti, et al877 Effect of fish oil on neutrophil chemiluminescence induced by different stimuli in patients with rheumatoid arthritis

M Magaro, A Zoli, L Altomonte, et al881 Pityriasis rosea and discoid eczema: dose related reactions to treatment with gold SM Wilkinson, A G Smith,

MJ Davis, et al885 Short term effects of intravenous pulses of cyclophosphamide in the treatment of connective tissue disease crisis

Hans-Jacob Haga, David D'Cruz, Ronald Asherson, et al889 Isotype profile and clinical relevance of anticardiolipin antibodies in Sjogren's syndrome AJedryka-Goral, PJagiello,

DP D'Cruz, et al892 Effects of coagulation temperature on measurements ofcomplement function in serum samples from patients with

systemic lupus erythematosus G Baatrup, G Sturfelt, A Junker, et al898 Gait analysis in ankylosing spondylitis L Zebouni, P S Helliwell, A Howe, et al

Case reports900 Giant cell arteritis of the female genital tract with temporal arteritis Francois Lhote, Claire Mainguene,

Valeie Griselle-Wiseler, et al904 Induction of remission in a patient with Takayasu's arteritis by low dose pulses of methotrexate Dror Mevorach,

Gil Leibowitz, MeyerBrezis, et al906 Infectious discitis caused by Enterobacter cloacae R Solans, P Simeon, R Cuenca, et al908 Digital vasculitis after splenectomy in a patient with Felty's syndrome M Comer, R C Bucknall

Masterclass910 Salvage of the infected arthroplasty AlistairC Ross

Now and then914 Health of the nation and osteoporosis Allan Stj Dixon

Review919 Angiogenesis and rheumatoid arthritis: pathogenic and therapeutic implications P R Colville-Nash, D L Scott

No 7 JULY 1992

on Novem

ber 26, 2020 by guest. Protected by copyright.

http://ard.bmj.com

/A

nn Rheum

Dis: first published as on 1 D

ecember 1992. D

ownloaded from

926

926927927928

No 8 AUGUST 1992

Letters to the editorAdhesion of peripheral blood lymphocytes to high endothelial venules of gut mucosa G S Panayi, G H Kingsley,C Pitzalis; Peter Sheldon, Aras KadiogluPotential for drug interactions in elderly patients with arthritis THunter; HowardBirdBronchiolitis obliterans in systemic lupus erythematosus D R Porter; B Godeau, C Cormier, CJ MenkesPamidronate associated hallucinations Darragh Foley-Nolan, MichaelJ Daly, David Williams, et alCorrection Ana Cilursu,JamesA Goeken, Richard R Olson

Leader929 HLA-B27 subtypes: implications for the spondyloarthropathies Lachy MacLean

Scientific papers932 A 12 year follow up study in the general population on prognostic factors of cartilage loss in osteoarthritis of the knee

Jan S A G Schouten, Frank A van den Ouweland, HansA Valkenburg938 Scintigraphic assessment of osteoarthritis of the knee joint Fiona McCrae, lennte Shouls, Paul Dieppe, et al943 Effect of disease severity on rheumatoid arthritis concordance in same sexed siblings CM Deighton, D F Roberts,

DJ Walker946 Circulating cytokine levels in patients with rheumatoid arthritis: results of a double blind trial with sulphasalazine

VA Danis, GradislavaM Franic, Deborah A Rathjen, et al951 Ankylosing spondylitis and monoclonal gammopathies G Renier,JI C Renier,M Gardembas-Pain, et al955 Evaluation of sulphasalazine in the treatment of spondyloarthropathies Maxime Dougados, Andreas Maetzel,

Mustapha Mijiyawa, et al959 Cellular immunity to cartilage proteoglycans: relevance to the pathogenesis of ankylosing spondylitis

PareshJobanputra, ErnestH S Choy, Gabrielle H Kingsley, et al963 Absence of a specific effect of free radicals on HLA-B27 I L MacLean,M WLowdell, D R Blake, et al965 Plasminogen activators in synovial fluid and plasma from patients with arthritis EJ P Brommer, G Dooijewaard,

B A C Dijkmans, et al969 Action of sodium aurothiomalate on erythrocyte membrane JM Campbell, J Reglinski, WE Smith, et al972 Night pain in arthritis: patients at risk from prescribed night sedation PG Hardo, S A Wasti, A Tennant974 Repetitive strain disorder: towards diagnostic criteria HA Bird, J Hill978 Detection of cytokine activated chondrocytes in arthritic joints from pigs infected with Erysipelothrix rhusiopathiae

M Elisabeth Davies, Alan Homer, Burkart Franz, et al983 Dependence of proteoglycan induced arthritis in BALB/c mice on the development of autoantibodies to high density

proteoglycans PaulH Wooley, Scott W Siegner, JaneyD Whalen, et al992 Uridine diphosphoglucose dehydrogenase activity in synovial lining cells in the experimental antigen induced model of

rheumatoid arthritis: an indication of synovial lining cell function A A Pitsillides, SM BlakeConcise report

996 Complications associated with labial salivary gland biopsy in the investigation of connective tissue disordersA Richards, S Mutlu, C Scully, et al

9981001

100510071009

Case reportsRemission of scleroderma during chemotherapy for lymphoma Marie Comer, AndrewR HarveyRecovery from pulmonary hypertension in an adolescent with mixed connective tissue disease DeborahM Friedman,HalJ7 Mitnick, Delores DanilowiczPalmar rheumatoid nodulosis associated with local pressure EldadBen-Chetrit, Claes Enk, Alan RubinowLong term treatment of chronic Lyme arthritis with benzathine penicillin MarcoA Cimmino, Silvano AccardoUlcerative colitis complicating seronegative HLA-A2-B27 rheumatoid arthritis with sacroiliitis TKlausen,K Amris, P HelinDispatch

1012 From the Netherlands A Cats, F C BreedveldReviews

1014 Role of substance P in inflammatory arthritis NE Garret, P I Mapp, S C Cruwys, et al1019 Does folate supplementation make sense in patients with rheumatoid arthritis treated with methotrexate?

Annemiek AME Stenger, PieternellaM Houtman, GeorgeA WBnynLetters to the editor

1021 Pseudohaemarthrosis: a new manifestation ofOsler-Rendu-Weber disease Jaime Calvo-Alen, Eduardo Loza,Jose L Alonso, et al

1021 Lupus anticoagulant activity and anticardiolipin antibody titre in patients with systemic lupus erythematosusDA Isenberg, CB Colaco; HJ Out, RH WM Derksen, Ph G de Groot

1022 Failure of cold pressor testing to induce changes in plasma renin activity or renal duplex sonography in patients withsystemic sclerosis GA W Bruyn,M S van Leeuwen

1022 Inactive al antitrypsin in rheumatoid synovial fluid: oxidation, proteolysis, or complex formation?DenisR Stanworth, Peter TDawes; PaulG Winyard, David R Blake, Keith Chidwick, et al

1023 HLA-D region genes and rheumatoid arthritis CM Deighton, DJ Walker; W Watson Buchanan, DP Singal1024 Liver toxicity with sulphasalazine WN Dodds; Dan Caspi

No 9 SEPTEMBER 1992 Leader1025 Bone mineral density and osteoarthritis SM Knight, E FJ Ring, A K Bhalla

Notes and news1027 The Volvo awards for low back pain research 1993 * XVIIIth ILAR congress of rheumatology

Book reviews1027 Rheumatology Review * Computer-assisted Diagnosis of Rheumatic Diseases1028 Articular Cartilage and Osteoarthritis * Osteoarthritis: Diagnosis and Medical/Surgical Management -

Rehabilitation of Early Rheumatoid ArthritisScientific papers

1029 Clinical significance of rheumatoid factors in early rheumatoid arthritis: results of a follow up studyDerkjen van Zeben,JohannaM W Hazes, AeilkoH Zwinderman, et al

1036 Decreased level of antibodies against Helicobacter pylori in patients with rheumatoid arthritis receiving intramusculargold MatthijsJanssen, Ben A C Dijkmans, Jan P Vandenbroucke, et al

1039 Recombinant human interferon y in the treatment of rheumatoid arthritis: double blind placebo controlled studyKlaus P Machold, Kurt Neumann, JosefS Smolen

on Novem

ber 26, 2020 by guest. Protected by copyright.

http://ard.bmj.com

/A

nn Rheum

Dis: first published as on 1 D

ecember 1992. D

ownloaded from

1044 Glutathione redox cycle enzymes and selenium in severe rheumatoid arthritis: lack of antioxidative response toselenium supplementation in polymorphonuclear leucocytes U Tarp, K Stengaard-Pedersen, J C Hansen, et al

1050 Systemic lupus erythematosus in men: clinical and immunological characteristics Josep Font, Ricard Cervera,Margarita Navarro, et al

1053 Correlation of antibodies to ribosomal P protein with psychosis in patients with systemic lupus erythematosusYNojima, S Minota, A Yamada, et al

1056 Preliminary observations of chondral abrasion in a canine model RoyD Altman,Jonathan Kates,Lawrence E Chun, et al

1063 Fracture thresholds in osteoporosis: implications for hormone replacement treatment Pi Ryan, GM Blake,I Fogelman

1066 Characteristics of immunocompetent cells in synovial membranes from multiple sites in patients with rheumatoidarthritis J G Hanly, D PledgerConcise reports

1069 Differential involvement of the dorsal and lumbar spine in osteoporosis M Bhambhani, AJ Crisp,J E Compston1071 False positive results for antibody to HIV in two men with systemic lupus erythematosus MariaH Esteva,

AnaM Blasini, Dalhia Ogly, et alCase reports

1074 Primary idiopathic osteolysis: description of a family Antonio Naranjo, MiguelA Muniain,J3avierMartin, et al1079 Mycotic aneurysm of the aortic arch masquerading as systemic lupus erythematosus K Chakravarty, D G I Scott1082 Temporal arteritis: a form of systemic panarteritis A Sendino, FJ Barbado, I Gonzalez-Anglada, et al1085 Systemic lupus erythematosus induced by isoniazid Mario Salazar-Paramo, Robert L Rubin,

Ignacio Garcia-De La TorreDispatch

1088 From India V RJYoshiReview

1089 Misoprostol in the prevention of gastroduodenal damage in rheumatology A B Ballinger, PJ Kumar, D L ScottHypothesis

1094 Human cartilage proteoglycans as T cell autoantigens J A Goodacre, J P PearsonLetters to the editor

1098 Sex ratios, HLA markers, and rheumatic diseases William HJnames, Lillian Staub Nielsen, Kirsten Fenger, et al1098 Class II antigen induction in cartilage J Bujia, E Wilmes, C Hammer, et al1099 Reduced serum 12 glycoprotein I in SLE Juzo Matsuda, Miyo Tsukamoto, Noriko Saitoh, et al1100 Anticardiolipin antibodies in rheumatoid arthritis B Seriolo, M Cutolo, D Fasciolo, et al1100 Multiple leiomyomas of the skin in RA Dan Buskila, Bernardo Mosovitch, Amnon Biton, et al1101 Pachydermodactyly: confused with JCA J C Martin, J A N Rennie, KM Kerr1102 Mycobacterium kansasii osteitis of the ischium Gilles Grateau, Gilles Valin, Daniel Sereni, et al1102 Age at presentation with ankylosing spondylitis William Hjames; Andrei Calin, Rob Will,3John Kirwan1103 Pregnancy and antiphospholipid antibodies Ugo Picillo, Maria Roberta Marcialis, Antonietta Longobardo, et al1103 Antireticulin antibodies in systemic sclerosis JamesB Peter, PeterN Hollingsworth; Mark Peakman, TaherMahmud,

Diego Vergani1104 Antiribosomal P antibodies and lupus psychosis Lee-Suan-Teh; Myron E Mavrikakis

No 10 OCTOBER 1992 Leader1105 How serious is knee osteoarthritis? TD Spector, DJ Hart

Scientific papers1107 Radiological progression of osteoarthritis: an 11 year follow up study of the knee TimD Spector, Jane E Dacre,

PatA Harris, et al1111 Radiographic patterns and associations of osteoarthritis of the hip Joanna Ledingham, Stewart Dawson,

Bryan Preston, et al1117 Exercise induced release of von Willebrand factor: evidence for hypoxic reperfusion microvascular injury in

rheumatoid arthritis AdrianJ Farrell, RichardB Williams, CliffR Stevens, et al1123 Relative contribution of contact and complement activation to inflammatory reactions in arthritic joints JJ Abbink,

A M Kamp,JH Nuijens, et al1129 Acute joint inflammation alters the adrenoceptor profile of synovial blood vessels in the knee joints of rabbits

E Gray, WR Ferrell1134 Keratan sulphate in rheumatoid arthritis, osteoarthritis, and inflammatory diseases TD Spector, L Woodward,

GM Hall, et al1138 Measurement ofHLA class I expression in ankylosing spondylitis Paul Creamer, John Edmonds, John Sullivan, et al1143 Dietary intake and nutritional status in patients with systemic sclerosis A-C Lundberg, A Akesson, B Akesson

Concise report1149 Treatment of severe thrombocytopenia in systemic lupus erythematosus with intravenous gammaglobulin

EJ terBorg, C GM KallenbergCase reports

1152 Central nervous system systemic lupus erythematosus mimicking progressive multifocal leucoencephalopathyBrian R Kaye, C Michael Neuwelt, Stuart S London, et al

1157 Mixed connective tissue disease presenting as a left sided pleural effusion YIlan, A Ben-Yehuda, E Okon, et al1159 Scleromyxoedema with features of systemic sclerosis UditN Verma, R R Singh, Ramnath Misra, et al1162 Retrocalcaneal bursitis in juvenile chronic arthritis Claudia Goldenstein-Schainberg, Carlos Homsi, Rosa Maria

Rodrigues Pereira, et alDispatch

1164 From Germany Gerhard L BachNow and then

1165 The 'GALS' locomotor screen Michael Doherty,jane Dacre, Paul Dieppe, eta!Reviews

1170 Mycoplasmas and arthritis Kati Hakkarainen, Hannu Turunen, Ari'Miettinen, et al1173 The venous footpump: influence on tissue perfusion and prevention of venous thrombosis A M N Gardner, R H Fox

Letters to the editor1179 Methotrexate, pneumonitis, and infection PJSM Kerstens,7 WA van Loenhout, A M Th Boerbooms, et al;

A AM E Stenger, PM Houtman; GJ Carroll, NJ Cook, G T Owen1180 The antiphospholipid syndrome: a syndrome in evolution R Sinharay

on Novem

ber 26, 2020 by guest. Protected by copyright.

http://ard.bmj.com

/A

nn Rheum

Dis: first published as on 1 D

ecember 1992. D

ownloaded from

1180 Anticardiolipin antibodies and renovascular hypertension Ermanno Rossi, Carlo Sani, Michele Zini, et al1181 D-Penicillamine and rheumatoid factor D R Stanworth; Evelyn V Hess, Moris Ziff1182 von Willebrand factor antigen in giant cell arteritis AJ Farrell, DR Blake1182 Renal cell carcinoma with acute monarthritis A H Isdale1183 Systemic mastocytosis and Sjogren's syndrome BadalPal; DJ Bac,M van Marwijk Kooy1184 Unusual rhombencephalitis in relapsing polychondritis J-B Wasserfallen, MD Schaller

No 11 NOVEMBER 1992 Reviews1185 Hypergammaglobulinaemia and autoimmune rheumatic diseases MichaelR Ehrenstein, DavidA Isenberg1188 Role of the sympathetic nervous system in chronic joint pain and inflammation B L Kidd, S Cruwys, P I Mapp, et al

Rheumatological stamp1191 Imhotep Yale Andelman

Notes and news1192 Forthcoming events

Book reviews1192 Second-line Agents in the Treatment of Rheumatic Diseases * Handbook of Drug Therapy in Rheumatic Disease:

Pharmacology and Clinical AspectsScientific papers

1193 Measurement of cold challenge responses in primary Raynaud's phenomenon and Raynaud's phenomenon associatedwith systemic sclerosis D O'Reilly, L Taylor, K El-Hadidy, et al

1197 Systemic lupus erythematosus on the Caribbean island of Curacao: an epidemiological investigation J C Nossent1202 Comparison of two approaches to measuring change in health status in rheumatoid arthritis: the Health Assessment

Questionnaire (HAQ) and modified HAQ Sue Ziebland, Ray Fitzpatrick, Crispinjenkinson, et al1206 Specificity of the proteus antibody response in rheumatoid arthritis CM Deighton,J Gray, AJ Bint, et al1208 Aetiological role of bacteria associated with reactive arthritis in pauciarticular juvenile chronic arthritis J Sieper,

J Braun, E Doring, et al1215 Lipoxygenase products in inflammatory synovial fluids and other exudates Patrick B Costello, AlanN Baer,

FloydA Green1219 Increased concentrations of nitrite in synovial fluid and serum samples suggest increased nitric oxide synthesis in

rheumatic diseases AdrianJ Farrell, DavidR Blake, RichardMJ Palmer, et al1223 Bone resorption by cells isolated from rheumatoid synovium J S Chang, JM Quinn, A Demaziere, et al1230 Sulphasalazine inhibition ofhuman granulocyte activation by inhibition of second messenger compounds

Gunnar Carlin, Richard Djursater, Goran Smedegard1237 Effect of intravenous iron-dextran (Imferon) infusion on antigen induced monarticular arthritis in rabbits CN Kind,

A Blackham, CJ MorrisConcise reports

1242 P blood group phenotype, proteus antibody titres, and rheumatoid arthritis CM Deighton, J Gray, D F Roberts, et al1245 Sequence similarity between HLA-DR1 and DR4 subtypes associated with rheumatoid arthritis and proteus/serratia

membrane haemolysins A Ebringer, P Cunningham, K Ahmadi, et al1247 Antibody response against 26 and 46 kilodalton released proteins of yersinia in yersinia triggered reactive arthritis

Outi Maki-Ikola, Matthias Pulz,3Jurgen Heesemann, et al1250 Does the locus on chromosome 11 implicated in susceptibility to HLA-DR4 dependent type I diabetes mellitus also

affect susceptibility to rheumatoid arthritis? KD Pile, B P Wordsworth, J I Bell1252 Use of a risk factor and dietary calcium questionnaire in predicting bone density and subsequent bone loss at the

menopause TD Spector, A C Edwards, P W Thompson1254 Complement factor 2 deficiency: a clinical and serological family study David D'Cruz,James Taylor,

TahirAhmed, et alDispatch

1257 From America: Cookbook medicine or food for thought: practice guidelines development in the USAMatthezvH LiangNow and then

1259 How to speak at international conferences V WrightViewpoint

1261 Drug derived radicals: mediators of the side effects of anti-inflammatory drugs? Barry Halliwell, Patriciaj Evans,Harparkash Kaur, et alLetters to the editor

1264 Antiperinuclear factor in chronic juvenile arthritis Robert von Essen, Heikki Ylijoki, Anneli Savolainen, et al;Gideon Nesher, Terry L Moore

1264 Diagnostic role of antikeratin antibodies in RA A 0 Adebajo, B L Hazleman, D G Williams, et al1264 Sulphasalazine induced hepatitis in adult Still's disease J Crowley, R D Situnayake1265 Longstanding HLA-B27 associated Achilles tendinitis Ignazio Olivieri, Angela Padula, Michele Lisanti, et al1266 Vasculitis in Klinefelter's syndrome William Kim, Winston Sequeira1267 Acute neuromyopathy after colchicine treatment Joukje van der Naalt, Hanny Haaxma-Reiche,

Arie P van den Berg, et al1268 Reactive arthritis and group G streptococcal pharyngitis L Young, CM Deighton, A3J Chuck, et al

Supplement1269 Second Jenner International Glycoimmunology Meeting

No 12 DECEMBER 1992 Reviews1287 Magnetic resonance imaging in rheumatology Christine W Heron1292 Epidemiology of systemic lupus erythematosus Neil Hopkinson

Notes and news1295 Forthcoming events

Book review1295 Rheumatic diseases

Extended reports12% Systemic and mucosal antibodies to klebsiella in patients with ankylosing spondylitis and Crohn's disease

S O'Mahony, N Anderson, G Nuki, et al

on Novem

ber 26, 2020 by guest. Protected by copyright.

http://ard.bmj.com

/A

nn Rheum

Dis: first published as on 1 D

ecember 1992. D

ownloaded from

1301 Autoantibodies in chronic arthritis of childhood: relations with each other and with histocompatibility antigensPeterN Malleson, Marinda Y Fung, Ross E Petty, et al

1307 IgG and IgM anti-snRNP reactivity in sequentially obtained serum samples from patients with connective tissuediseases UlfNyman, Ingrid Lundberg, Eva Hedfors, et al

1313 Clinical associations of IgG antibodies to the ribonucleoprotein p67 polypeptide in patients with systemic lupuserythematosus J Vencovsky, D G Williams, M Field, et al

1318 Continuation of long term treatment with hydroxychloroquine in systemic lupus erythematosus and rheumatoidarthritis E F Morand, P I McCloud, GO Littlejohn

1322 What is the contribution of occupational environmental factors to the occurrence of scleroderma in men?AlanJ Silman, Steven3Jones

1325 Work related upper limb disorder: the relationship between pain, cumulative load, disability, and psychological factorsP S Helliwell, DB Mumford,7 E Smeathers, et alConcise reports

1330 Methotrexate treatment of rheumatoid arthritis: is a fortnightly maintenance schedule enough? Moshe Tishler,Dan Caspi, Michael Yaron

1332 Long term prognosis in yersinia arthritis: clinical and serological findings J D Herrlinger,J-UAsmussen1335 Giant cell tumours in mandible and spine: a rare complication of Paget's disease of bone M Bhambhani,

B GH Lamberty, M R Clements, et alCase report

1338 Coexisting HLA-B27 positive spondyloarthritis and polyarteritis nodosa M A SattarDispatch

1340 From the Pacific Basin PeterBrooksLetters to the editor

1342 IgG rheumatoid factor synthesis in synovial fluid S Visvanathan, P WRobertson,J VBertouch1342 Postpartum autologous plasma transfusion: effect on RA CraigD Scoville1343 Colchicine myoneuropathy and renal dysfunction Steven A Older, DavidS Finbloom, Gholam H Pezeshkpour1344 Polyarteritis nodosa and acute interstitial pneumonia TMatsumoto, M Okada, N Kuwabara, et al1345 Radiographic assessment of the knee joint in OA Bruce M Rothschild; Cyrus Cooper,J7ohn Kirwan, Paul Dieppe1346 Author index1360 Subject index

on Novem

ber 26, 2020 by guest. Protected by copyright.

http://ard.bmj.com

/A

nn Rheum

Dis: first published as on 1 D

ecember 1992. D

ownloaded from