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SIE APRIL 15, 1949 A COLOR TRANSLATING ULTRAVIOLET MICROSCOPE E. H. LAND, E. R. BLOUT, D. S. GREY, ET A4L. THE BY TARGET THEORY EXAMINED DEUTERON BOMBARDMENT OF T-1 PHAGE ERNEST C. POLLARD AND FREDERICK FORRO, JR. TECHNICAL PAPERS COMMENTS & COMMUNICATIONS NEWS AND NOTES COMPLETE TABLE OF CONTENTS ON PAGE 3 VOLUME 109, NUMBER 2833 b m uinhuu m mi e _mu THE ADVANCEMENT OF SCIENCE I I I I I I I I I F' I I I I I I Iy I Io Io AMERICAN ASSOCIATION FOR E...m .m Offi Maa ..M .l

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SIE

APRIL 15, 1949

A COLOR TRANSLATINGULTRAVIOLET MICROSCOPE

E. H. LAND, E. R. BLOUT, D. S. GREY, ET A4L.

THEBY

TARGET THEORY EXAMINEDDEUTERON BOMBARDMENT

OF T-1 PHAGEERNEST C. POLLARD AND FREDERICK FORRO, JR.

TECHNICAL PAPERS

COMMENTS & COMMUNICATIONS

NEWS AND NOTES

COMPLETE TABLE OF CONTENTS ON PAGE 3VOLUME 109, NUMBER 2833

b m uinhuu m mi e_mu

THE

ADVANCEMENT OF SCIENCE

IIII

IIIIIF'

IIIIIIIy

I

IoIo

AMERICAN ASSOCIATION FOR

E...m .m OffiMaa..M .l

mass demonstration In the auditoriumThe projectionist can follow a specimen through a progres-Sive series of ever-closer localizations, from its gross aspectto its ultimate microscopic demonstration under oil-immersion

The auxiliary Scopicon dark-chamber "round-table"

affords superb facility for small-group study.Here the projected image is cast upon a platenwithin a light-tight chamber, with separate light'excluding viewing hoods for each observer. Anynumber up to ten may share in conference, which

can be conducted in a normally lighted room. A

pointer at each port permits any observer to indi-

cate areas of interest to all the others for discussion.

. . . and for

in a normallyE1-.A-E~ ___lighted

-~~~~~~~~~~~fi

SCOPICON, Inc.215 East 149th St., New York 51, N. Y.

a room

April 15, 1949, Vol. 1

Turner 'sGENERAL ENDOCRINOLOGY

*. . a truly biologic

approach to ` ,

endocrinology, '

with 349 illustrations '~ 2jX1)

like this one

The effects of hypophysectomy upon the genitalsystem of the male rat. A, genital system froma normal male rat 7 months of age. B, genitaltract from a littermate brother hypophysecto-mized when 30 days old and autopsied at 7months of age. (Drawn to scale. See Fig. 67for the identity of parts. The parts are notlabeled here because this is not an anatomicaldrawing.)

This comprehensive text has proved popularwith teachers everywhere, because it is thefirst book that approaches endocrinology ona truly biologic level. It removes the subjectfrom its purely clinical niche and makes of italmost a basic science, to be studied-andunderstood-in its anatomic, physiologic, andembryologic aspects.The illustrations, too, make up an importantfeature. There are 345 of them (on 164 fig-ures) and most of them were drawn especiallyfor this book. In anatomical drawings thelabelling is done right on the parts, to makerecognition easy. Many microscopic repre-sentations were redrawn so as to bring outmost forcibly the point under discussion.

Every single aspect of the subject is thor-oughly explored and clearly explained. Thereis detailed information on historical factors;experimental and clinical methods; interrela-tions of glandular activity; evolution and em-bryology of all types of regulation in plantsand animals; and, of course, there is a wealthof data on the individual glands themselves.Because of this completeness, the book issuited for use in either advanced collegeclasses or in postgraduate courses.

By C. DONNELL TURNER, PH.D., Chairman of the Depart-ment of Biology, Utica College of Syracuse University.604 pages with 349 illustrations on 164 figures. $6.75.(Copies gladly sent to teachers for consideration as a text.)

W. B. SAUNDERS COMPANYWest Washington Square

April 15, 1949, Vol. 109 SCIENCE 1

.

Philadelphia 5

2 SCEC pi 5,14,Vl

p NEW and Radically DiffrentMODERNIZED FOR...

* MORE ACCURATE READING* LOWER MAINTENANCE COST* EASIER, FASTER OPERATION

This New Streamlined Bausch & Lomb"Abbe 56" REFRACTOMETER

is a lot of refractometer for the money

Note these 10 Features:PRISMS: Prisms set in Durisite cement in waterjacketed housings. Easy to clean and resistant tofruit acids and most chemicals.ILLUMINATION: By daylight or other outsidesource reflected by mirror, or by artificial lightfrom built-in lamp.TELESCOPE SYSTEM: Correct dividing linesetting indicated by red coloration at one end ofline, bulb at the other, and neutral (achromatized)portion in center. A(ljustment for compensationcan be made precisely.MECHANISM: Operating arm always in low posi-tion with user 's arm resting in comfortable posi-tion on table. Fast motion by use of large wheel.Position drive through screw and worm nut. No

clanmps or tangent screw to exert pressure on

bearing.

INTERNAL TRANSPARENT GLASS SCALE:Protected from dirt and corrosion. Theoreticalaccuracy: .0001. Calibrated for both refractiveindex and percentage sugar. Ref. Index 1.30 to1.71; per cent sucrose 0 to 85. Illuminated withdaylight through window in side wall or by in-ternal electric lanmp operated by hold-down switch.THERMOMETER: In vertical plane close to in-strumiemt housing. May be adjusted for easy view-ing by locking nut.EYEPIECES: Scale reading and telescope eye-pieces inclined and inl position close together forconvenience and speed in reading. Scale moves;eyepieces stationary.HOUSIN-G: Streamlined housing cov-ers scale andall moving parts. Internal parts easily accessiblefor adljustnieimt lbut lProtected from damage bydust, fumnes anid stray liquids.STAND: Heavy, stuirdys, durable base assures re-producibilitv of readings. Low center of gravity.Hard to tip over. Carrying handle for portability.Detachable drip pan between feet.FINVISH: Hard, glossy, durable, gray lacquer.Eyepieces, handle, operating wheel chrome lplated.14653-REFRACTOMETER, Bausch & Lomb,"Abbe-56", as above described, with refractive in-dex scale 1.30 to 1.71 (reading accuracy .0002)and sugar scale 0 to 85% in 0.5% divisions. Ther-mometer 0 to 750 C. in 1° divisions and adlustablefor vertical angle and rotation. Removable drippan. For 1 1 5 volt, 60 cycle A.C. complete in hard-wood carrying case with lock and key, glass testpiece; bottle 1 -bromophthalene (7 ml.), wrenches,direction book and dispersion table .... $585.00

For Descriptive Booklet on the "Abbe 56":

Write, Teletypewrite, Wire or Phone Dept. S-4 our Nearest Office-Warehoiuse

1

2 SCIENCE April 15, 1949, Vol. 109

j:. il,'mi

3

A,

SC! ~~~~~~~~~~~~~~~~~~(TibarC I E C EArthur C. Bev.Vol. 109 No. 2833 Friday, April 15, 1949 Malcolm H. S(

4F. A. Mc

CONTENTlS

A Color Translating Ultraviolet Mi-croscope:E. H. Land, E. R. Blout,

D.S.Grey, et al. ........ ...................... 371

Examination of the Target Theoryby Deuteron Bombardment of T-1Phage:Ernest C. Pollard and

FrederickForro, Jr .................... 374

Technical PapersDirect-reading Photocolorimetry:

JohnG. Reinhold ........... .............................. 376

The Separation of Purine and PyrimnidineBases and of Nueleotides by Ion Exchange:Waldo E. Cohn ....................... . ....... 377

A Simplified Procedure for the AnalyticalExtraction of Lipids:

Joseph J. Kolb 378

Evidenceethi.t Amputation of Bacterial FlagellaDoes Not Affect Motility:Adrianus Pijper .......... ............................ 379

A Simple Technique for Continuous Registra-tion of Blood Flow:

G.K.Moe ....................................... 381Inhibitor in Onion for Starch Synthesis:H. C. Eyster .......... ......... 382

The Isthmic Mucous Membrane of theHuman Uterus:D. N. Danforth and James C. F. Chapman 383

Physical Studies on Corneal Tissues:H. J. Adler, S. T. Gross and J. M. Lambert 383

Comments and CommunicationsModified Ninhydrin Reagent in Quantitative

Determination of Amino Acids by PaperChromatography; More on High School

BiologyRequirements ............... ....................... 385

News and Notes 387

Science, a weekly journal founded- in 1880. is publishedeach Friday by the American Association for the Advance-ment of Science at the Business Press. 10 McGovern Ave..Lancaster, Pa. Editorial and Advertising Offices. 1515 Massa-chusetts Ave., N.W., Washington 5, D. C. Telephone. Execu-tive 6060. Cable address, SCIMAG, Washington. D. C.Entered as second-class matter at the Post Office at Lancaster.Pa., January 13, 1948, under the Act of March 3. 1879.Acceptance for mailing at the special rate postage providedfor in the Act of February 28, 1925, embodied in Paragraph 4,Sec. 538, P.L. and R., authorized January 13. 1948.

Manuscripts submitted for publication should be sent to theEditorial Offlie, with stamped, self-addressed envelope enclosedfor possible return. The AAAS assumes no responsibility forthe safety of the manuscripts or for the opinions expressedby contributors.

Annual subscription, $7.50; single copies, $.25: foreignpostage, outside the Pan-American Union, $1.00: Canadian

postage, $.50. Remittances and orders for subscriptions andsingle copies should be sent to the Circulation Department.Science, 1515 Massachusetts Ave., N.W., Washington 5. D. C.Membership correspondence for the AAAS should be addressedto the Administrative Secretary at the same address.

Change of address. Four weeks' notice is required forchange of address. This should be sent to Science Recorder.1515 Massachusetts Ave., N.W.. Washington 5. D. C. Whenordering a change, it is necessary to furnish an address stencillabel from a recent issue. Claims for a missing number willnot be allowed if received more than 60 days from date ofissue. No claims allowed from subscribers due to failure tonotify the Circulation Department of a change of address orbecause an issuers missing from their files, or for any reasonfrom subscribers in Central Europe, Asia, or the Pacific Islands(other than Hawaii).

The AAAS also publishes The Scientific Monthly. Subscrip-tion rates on request.

BAAS EDITORIAL BOARDerms empire Jugly 31, 1949)ran Edward U. Condon

H. Bentley Glassoule Everett S. Wallis

George A. BaitsellEditor-in-ChiefBeth Wilson

Executive Editor of Science

vulton. Advertising Representative

SCIENCE April 15, 1949, Vol. 109

ELv,. .L

ETER

o RAPIDo AUTOMATICo RELIABLE

The Cenco-Patterson Electronic Mois-ture Meter was developed originally forthe milling industry to enable rapid, ae-curate and automatic determinations ofmoisture in flour and wheat. It is directreading, push-button operated from 115volt lines, stable, self-containe(d and isbeing successfully applied to read themoisture content of flour, wheat, rye.coffee beans, popcorn, corn, oats, kaffir.

Moisture readings are accuratemeasurements of electrical capaci-tance. The range and accuracy ofthe instrument, where applicable,is sufficient to cover most indus-trial materials.

Write for descriptivebarley and other similar materials. Po- information and prices.tential applications are many. although Ask for CNC63.at present confined to granular and(lpowdered substane~s. %,I SAv

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l@ *.a is *z SP i..E . * S* *

4 SCIENCE April 15, 1949, Vol. 109

April15,1949,Vol. 109 SCIENCE 5~~~~~~~~~~~~~~~~~~~-

International R rigeratd CentrifugeCentrifugation under controlled tempera-

tures at or well below 00 C. offers new possi-bilities tb the biochemist. The cancer program-virus investigations-polomyelitis research-enzyme research-low temperature solventfractionation-all have benefted ly the use ofthis new research tool. Countless other appli-cations are waiting the guidance ofthe researchscientist.

The International Portable RefrigeratedCentrifuge, Model PR-1, is now equipped

with a larger capacity compressor. Centrifugespeeds and capacities remain unchanged, butmuch lower controlled temperatures are nowpossible. For example, with six 100 ml. tubesat 5000 r.p.m., temperatures as low as -15'C. can be maintained; with four 250 ml.bottles at 2600 r.p.m., -8° C.; with four25 ml. tubes at 18,000 r.p.m., -5° C.

Here is a scientifically designed researchinstrument definitely worth investigating.Write for descriptive Bulletin RC, 1949.

INTERNATIONAL EQUIPMENT COMPANYBoston 35, Massachusetts

April 15, 1949, Vol. 109 SCIENCE 5

6~ SCEC pi 5,14,Vl 0

S .e . G~~~~~~WI M..

/S g em_:E~~~~~i==:=~~~AM.d EL -K --~ a 1 1 lok-AM -X KEM -2 -it 112~

6 SCIENCE April 15, 1949, Vol. 109

April 15, 1949, Vol.109SCIENCE 7~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

ANOTHER FIRST* . .

OPAQUE PROJECTION

Newly developed AC motor operates without noise

Free Demonstration ilUpon Request -

Write for descriptive booklet toDept. B.

Beseler VU-GRAPH also availablewith quiet AC< motorBeseler-Nu-Graph is the amazing OverheadProjector that enables you to face yosraudience while you project an image on thescreen behind you. The Vu-Graph can beobtained with the new, quiet AC motor,if desired.

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The World's Largest Manufacturer of Opaq.ue Projection Equipment

I1

April 15, 1949, Vol. 109 SCIENCE 7

SCIENCE April 15, 1949, Vol. 109

NEW throughout, from base, housing, and 1eyepito thermometer... the new Bausch & Lomb "Abbe-56"Refractometer brings you many new exclusive designfeatures ... for easier, lower cost operation ... formore accurate readings. In addition to the four im-portant performance advantages shown at the rightthere are advanced-design features in the telescopesystem, operating mechanism, prism cement, ther-mometer stand, and finish. And, with all these newadvancements ... there is so premsim price tag.

WRITE for complete information and a demonstra- NEtion to Bausch & Lomb Optical Company, 642-G eyepSt. Paul Street, Rochester 2, N. Y. for 1

Bausch & Lomb

W1 Inclined. fixed-positionpieces mounted close togetherreading comfort.

-56 'i edra tometer

8 SCIENCE April 15, 1949, Vol. 109