april 1976 vol. nine no. two fluoride · martin luther universtgt robert winship memorial clinic...
TRANSCRIPT
April 1976 Vol. Nine No. Two
FLUORIDE
OFFICIAL QUARTERLY JOURNAL
OF
OFFICERS
President Vice President Second Vice President H. M. Sinclair, M. D., D. Sc.
Utah State University Laboratory of Human Nutrition Medical College Logan. Utah Oxon, England Patiala, India
Prof. G. W. Miller, Ph. D. Prof. S. S. Jolly, M.D.
Secretary G. L. Waldbott, M.D. Warren, Michiwn
Prof. G. Fraddi, M.D. Institute of Occupational Medicine
University of Palermo. Italy
Prof. G. Halbwachs, Ph. D. Institute of Botany Vienna, Austria
Prof. Dr. G. Rosonberger Veterinary University
Hannover, Germany
MUDr. G. Baluova CSc.
ADVISORY BOARD
J. V. Marhold, M. D., Ph. D. Research Institute for Organic Synthesis
Pardubice, CSSR
Prof. J. 6. Patrick, Ph. D. Mary Baldwin College Staunton. Virginia
Prof. F. Pinot, M.D. RMne, France
EDITORIAL BOARD
Prof. G. Neil Jenkins Research Institute for Hygiene The Dental School, Univ. of
Bratislava, Czechoslovakia Newcastle Upon Tyne, England
Dr. Ernest Bovay, Director Jerry Krechniak, Ph. D. Akademia Medyuna,
Liebefeld Bern, Switzerland Gdahsk, Poland
John R. McLaren, M.D.
Federal Agric. Research Station
J. Franke, M.D.
Treasurer P. E. Zanfagna, M.D.
Lawrence, Massachusetts
A. H. Siddiqui, M.D. Coon Rapids, Minnesota
Prof. Reni Truhaut, Ph. D. Facult; De Pharmacie Univenit i do Paris, France
Prof. A. W. Burgstahler, Ph. D. University of Kansas
Lawrence. Kansas
Prof. Frederick W. Oehme, D.V.S. Kansas State University Manhattan, Kansas
Prof. Albert Schatz, Ph. D. Temple University
Philadelphia, Pa.
Carlo Mangoni di S. Stefano, M. D. Martin Luther Universtgt Robert Winship Memorial Clinic Instituteof Human Physiology
Halle/Saale, DDR Emory University University of Naples, Italy Atlanta, Georgia
Prof. S. P. S. Teotia, M. D. Department of Human H. Hanhijawi, D. D. S.
Korpilahti, Finland Metabolism Medical College
University of Meerut, India. K.A.V.R. Krishnamachari, M.D. National Institute of Nutrition
Hyderabad, India
Vol. Nine No. Two April, 1976 Pages 71-122
FLUORIDE Quarterly Reports
Issued by THE INTERNATIONAL SOCIETY FOR FLUORIDE RESEARCH
Editor G. L. Waldbott, M. D.
Warren, Michigan
Co-Editors A. W. Burgstahlor, Ph. D.
Lawrence, Kansas J. A. Yiamwyiannit, Ph. D.
Monrovia, California
CONTENTS
ED IT0 R I A L The Skeletal Changes in Chronic Fluorosis . . . . . . . . . . . . . . . . . .
ORIGINAL ARTICLES Populational Variation of Fluoride Parameters in Wild Ungulates
from the Western United States - by E. Kay, P.C. Tourangeau, and C.C. Gordon, Missoula, Montana ....................
Skeletal Fluorosis: Roentgenological and Histopathological Study by S.P.S. Teotia, M. Teotia and N.P.S. Teotia, Meerut, India . .
Treatment of Endemic Fluorosis in Human Beings: An Experimental Study - by S.P.S. Teotia, M. Teotia, and R.K. Singh, Meerut, India .................................
SPECIAL ARTICLE Possible Effects of Fluoride on the Thyroid - by J.R. McLaren,
Atlanta, Georgia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ABSTRACTS
Dietary Fluoride Intake of Infants - by E. Wiatrowski, L. Kramer, D. Osis, and H. Spencer, Hines, Illinois.. . . . . . . . . . . . . . . . . .
The Role of Calcium and Fluoride in Osteoporosis in Rhesus Monkeys - by H.J. Griffiths, R.D. Hunt, R.E. Zirnmerman, H. Finberg and J. Cuttino, Boston, Massachusetts . . . . . . . . . . . . .
Long Term Results of Mass Mouth Rinsing with Sodium Fluoride Solution in the Republic of Cuba - by V. W. Kunzel, F. Soto, J. Maiwald and R.C. Borroto, Leipzig, DDR and Havana, Cuba
71
73
91
98
105
116
117
1 i a
Increased Caries-Incidence by Oral Inoculation of Cariogenic Bacteria in Rats after Dietary Fluoride - by W.B. Clark, S.N. Kreitzman, and T.H. Howell, Atlanta, Georgia . . . . . . . . . . . . .
Relationships of Human Plasma Fluoride and Bone Fluoride to Age - by F.M. Parkins, N. Tinanoff, M. Moutinho, M.B. Anstey and M.H. Waziri, Iowa City, Iowa.. .....................
120
121
Fluoride Toothpaste: A Cause of Acne-Like Eruptions - by M.A. Saunders, Jr., Virginia Beach, Virginia . . . . . . . . . . . . . . . . . . . 121
FLUORIDE is published quarterly by THE INTERNATIONAL SOCIETY FOR FLUORIDE RESEARCH, INC.,
I SUBSCRIPTION RATES - Price per annum in advance I including postage $18.00; Skrgle copies $5.00.
MANUSCRIPTS for publication should be submitted in English, double-spaced with generous margins References should be arranged according t o the order in which they are cited in the text, and written as follow: Author, title, journal, volume, pages a d year. Each paper mus& contain a summary of not more than 12 lines.
Contributors will receive copier of the h u e of FLUORIDE containing their paper, free of charge.
FLUORIDE is listed in Current Contents Agricultural Food and Veterinary Sciences
Ear l ie r it was suggested t h a t t he amount of d ie ta ry fluoride was directly re la ted t o ungulate density through overgrazing and t h e associ- a t e d ingestion of soil-contaminated forage. This may also explain a pro- portion of t h e observed geographic fluoride variation, since the m o s t crowded bighorn sheep had t h e g r e a t e s t concentrations of skeletal fluo- r ide (23 - 28). However, o the r parameters allied with aggregate fluoride composition and utilization of na tura l mineral licks, f o r example, should be investigated before a definitive conclusion is formulated.
Interspecific Variation: Fluoride concentrations in ungulates collected on the National Bison Range (Table 7) established a degree of species variability, bu t insufficient sample sizes precluded s t a t i s t i c a l evaluations. animals a r e young and t o disappear with age. observed in cervids f r o m the Sapphire Mountains (Table 8). species specific fluoride accumulations were not definable which, in a l l like- lihood, was due t o these ungulates' submaximal population densit ies o r t he i r parallel forage preferences (29, 43 - 45).
The specific differences appear t o be minimal when the An identifical tendency was
In these instances,
TABLE 7
ppm f luor ide P a r a m e t e r s of Ungulates from t h e National Bison Range
Species AgeClass N j z SD cv SEji EX!& --
Bighorn sheep 3.5 yea r s 4.5-5.5 6. 5-7. 5 8+
Mule dee r 1 .5 yea r s 2.5 3. 5 4.5 10 +
Whitetail dee r 1.5 yea r s 2.5 3. 5
Pronghorn an te lope 1 month 2 3 6 8
1 5 27
2 81 .5 7 132.4 4 139.8 2 186.5
1 124.0 3 183.0 3 187.7 2 375.0 1 456.0
3 136.0 2 130.0 5 247.4
1 5.0 1 14.0 1 29.0 1 53.0 1 81.0
12 104.1 3 154.0
3 . 5 4 5 yrs . 2 162.0 5.5-6.5 3 190.0 9.5-12.5 3 363.7
Rocky Mountain 4 yea r s 1 253.0 goa t 5. 5 1 212.4
6.5 1 277. 1 9 1 288.9
21.9 29.5 10.2 27.2
46.1 49.4 32. 5
2 1.8 43.8 85.7
29.9 43.9
7 .1 34.7
103.2
26.9 22.3
7.3 14.8
25.2 26.3
8.7
16 .0 33.7 34.6
28.8 28.5
4.3 18.3 28.4
15. 5 11.1
5. 1 19 .5
26.6 28. 5 23.0
12.6 31. 0 38.3
-
8.6 25. 3
5. 0 20. 0 59.6
-
19.0 8.4 3.7
10 .4
14.6 15.2
6.1
9.2 23.8 15 .5
-
8. 3 16. 5
3.1 10 .5 16 .4
~~ ~~
Volume 9 Number 2 A p r i l 1976