A,j) & ,/,,sth [}* ,

~

w v 1. APPLICATION FOR:J .Pc;M NRC 313 I "UA. NUCLE A:4 L:E:tWLATom y COMMISSION

.

* < s.w- .tcsoes endier compxte a aooroorztel

to ce R so

( APPLICATION FOR BYPRODUCT MATERIAL LICENSE'

INDUSTRIAL X a. NEW L' CENSE

b AME NDME NT TO 'See ersached enstructoons for notortL LIGEh55 NVMBEM

Completed applicoroons err fooed on dupIncate evith the Oiersoon of Fur! Cycor and Meternet setery,O'fott of Nucers! Meter s! Sefery, and sofrguseds, U.S. Naclese Repuistory Commossen,o

Washington, DC 205$6 or opptocotoons iner be fated on perso*t at the Commission's offsce at '' *|g~, #N*[gg

1717 H Street, NW, Washington. O C. or 1915 Eastern Avenue. Siteer Sonne. Marytend.

'

2. APPLIC ANT'S NAME (institut,on, farm, person, etc./ 3. NAME OF PERSON 70 SE CONT ACTED REGARDINC THisAPPLICATION

*Lufkin Medical Laboratories Joseph R. Giganti, Ph.D.

TELEPMONE NUMBE R. AhE A CODE - NUMBER EXTEwSiON TE LEPMONE NVMstm: Am1 A cDDE - NUMBE m EXTEN5 BON

612-335-6521' 612-452-49824. APPLIC ANT'S MAILING ADDRESS (lactuce Esp Codel 6. STREET ADDRESS WHERE LICENEED MATERIAL WILL SE USED

(include Zop Code)

P.O. Box 629 1103 Second Ave'. SouthMinneapolis, MN 55440 Minneapolis, MN. 55440 *

(IF MORE SPACE IS NEEDED FOR ANY ITEM, USE ADDITIONAL PROPERLY KEYED PAGES.1

6. INDIVIDUAL (S) WHO WILL USE OR DIRECTLY SUPERVISE THE USE OF LICENSED MATERIALtsee stems te end 17 ror roouared trounons and onpornonce of **ch ondrecust named brewi

FULL NAME TITLE

Richard L. Reece, M.D.'

Pathologist, Partnere.

Edward. A. Kaufman, M.D. Pathologist3.

c.

I A$ rtsch a resume of person's trooning and rapertence as outtonec en items1. R ADLATION PROTECT 80N OF F SCER

|16 and 17 and descrske het responsbolstres under item 16.Joseph R. Giganti, Ph.D.

S. LICENSED MATERIAL

L ELEMENT CHEMICAL NAME OF MANUF ACTURER M AXIMUM NUMBER OF

1 AND AND/OR AND MILLICURIES AND/OR SE ALED

N MASS NUMBER PHYSICAL FORM MODEL NUMBER SOURCES AND MAXIMUM ACTI.(t/ Seeled Sourev/ VITY PE R $0URCE WHICH WILL

E 81 POSSESSFD AT ANY ONE TIME

NO A B C D,

-

.003 m01^

'" I-125 RI A Kit -----

.001 mci(2i Co-57 RIA Kit -----

-

(35 I-129 Rod Check Sourcc I.C.N.#77313 .00001 mci

(4)

DESCRIBE USE OF LICENSED MATERIALE

HI Exclusively Radioimmunoassays procedures using prepared kits c

(2) e n ,.u , nc n h n ve,

(35 Well Counter, counting ef fiency checks for I-125

44) |

POmu hmC 313 e l&78) { r

I

'# M !8 0 Ic1l0353 |_ _

'

!_

- - - _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ ____ _ _ _,

. .

Iii

Om (J'~

,..

, ..

9. STOR ACI OF SE ALED SOURCES -- -

t CONT AINER ANDrom DEv CE IN wHeCH EACH SEALED NAME or MANUF ACTURER moDEL NUMBER

g SOURCE wiLL DE STORED OR USED. : i

e.o. A. s. c.

tti + NOT APPLICABLE

(2s

(3)

s; (4)

,

10. R ADIATION DETECTION INSTRUMENTSTYPE M ANU F ACTU RE R1, MODEL N UMBE R R ADIATION SENSITIVITY

OF NAME WUMSER AVAILABLE DETECTED RANCE.

en ENSTRuMENT letphe, bets, imittorventrenshour

,E,' gemme, nesttron) er sounts/mmerelA e C D E F |

490"t hya c'' 1 gamma:6 Kev,up 0-20mR/hr l.

UI 3-M Survey Victoreen 489-110 "pa ncake" prob 3 Beta:35 Kev uo windows 1.4 mg/c m

Well Counter(2) Beckman 4000 1 gamma:8 Kev up 0-100,000 cts

(automatic)Q)

14) .,

11. CALIBRATION OF INSTRUMENTS LISTED IN ITEM 10

Da. CALtBRATED BY SERVICE COMP ANY get CALIBRATED SY APPLICANTAtrech a separete aAeet Weser4:np swt8:act, ftpoue.wg eNruence oss

N AME, ADDRESS, AND FRE00ENCYassed for celbratmg onstrumentL

.

12. PERSONNEL MONITORING DEVICESTYPE $UPPLIER EXCHANGE FREOUENCY

ICheca and/or complete es wropriore.1 l$ernce Company} CA B

D(1) FILM B ADGE NONE D MONTHLY

D(2) THE RMOLUMINESCENCE D QUARTERLYDO$tMETER (TLD> .NONE

,

D t3) OTHE R ispecity): D OTHER (Specity):,,

13. F ACILITIES AND EQUIPMENT (Check were appropriate and attach annotsted sketch (es) and description (s).

D a. LABDRATORY F ACILITIES, PLANT F ACILITIES, FUME HOODS (lachide filtrarfen, frony),ETC.O b. STOR AGE F ACILITIES. CONT AINE RS, SPE CIAL SHIE LDING (fimec enaAr temporaryl. ETC.O c. REMOTE H ANDLING TOOLS OR ECU6PMENT,E.TC.O e. RESPIRATORY PROTECTIVE EQUIPMENT, ETC. *

14. W ASTE DISPOSALa NAME OF COMMERCIAL W ASTE DISPOSAL SERVsCE EMPLOYED

NONE USED,

b.tF COVMERCIAL W ASTE DISPOSAL SE RVICE IS NOT EMPLOYED,5UBMIT A DETAILED DESCRIPT40N OF METHODS WHICH WILLDE USED FOR DISPOSING 0F RADIOACTIVE WASTES AND ESTIMATES OF THE TYPE AND AMOUNT OF ACTIVITY INVOLVED.IFTHE APPLICATION IS FOR SE ALED SOURCES AND DEVICES AND THEY WILL SE RETURNED TO THE MANUF ACTURER,SO STATE.

,

Included herewith

PORM tsRC 313 448 78). ,

*.

e***" e e

4

.

-.

', 3e ?

0 lI' 1

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. .

INFORMATION REQUIRED FC'R ITEMS 15,16 AND 17''

iDescribe in detall the information required for items 15,16 and 17. Begin each item on a

i esperate page and key to the application as follows:

9

15. MADIATION PROTECTION PROGRAM. Describe the radiation protection proprem es appropriate forthe material to be used including the duties and responsibilities of the Radiation Protection Ott cer, ,.

sontrol measures, bioassay procedures fd neeasdl, day today generat safety instruction to be followed,etc.11 the application is for sealed source's else submit leak testing procedures, or if leak testing will beperforrned using a lenk test kit, specif y manufacturer and model number of the leak test kit.

,

16. FORMAL TRAINING IN RADIATION SAFETY. Attach a resume for each individual named inj ltems 6 and 7. Describe individual's formal training in the following areas where applicable. include

the name of person or institution providing the training. duration of training when training wasreceived, etc.

Ia. Principles and practices of radiation protection.

b. Radioactivity measurement standardi2stion and monitoringtechniques and instruments.

c. Mathematics and calculations basic to the use and measurement of *

radioactivity.

d. Biologics! effects of radiation. -

17. EXPERIENCE. Attach a resume for each individual named in items 6 and 7. Describe individual'swork experience with radiation. including where experience was obtained. Work experience or sn-the-hb training should be commensurate with the proposed use. Include list of radioisotopes andrnaximum activity of each used.

18. CERTIFICATEITha trem must be completed by apolownt)

.-

The soplacent end eny O fecte! esecepting this cersdooste en behoff of the appl. cent nerned en item 2,f

aertify that this applacetoon is prepared in conformity evith Tot * E0. Code of recerer Mapuntoons,Port 30. end ther ett information contenned hereon encludong any suppements atteded hereto, at trueend correct to the best of our anowooge end motorf,

w ARNtNc.-is u.sc..s.enon 1001; Act # June 25,1948. E2 Stat.749. maken et e eriminst offene. so make a wittf uth talw swoment er..o montsten se en, e. sm.m e, .e.ncy of she unit.o swa ei ne on, m eter wah.. na p.m.eten.

.

e. LicENst FEE REQUIRED b. C RTIF,YlNG OFFICIAL wru's)

y yy .,, g M }tser secson src.21 to Crn sim

$110.00 c. Naut tr,,w ery,nts , O h & \ C H M,tx

kHO CTSpecific Byproduct

e. TITLE (, ART I'M O(ode]L.8tl LICENSE FEE CATEGORY:material, other

/''

(2) LICENSE FEE ENCLOSED: 8 110.00 g ,4' e oRW 8snC413 4 s6 78) a

.- _ --___- ._. ._ . _ _ _ - - _ _ . _ - _ _ _ - . _ - _ - _ - - _ - _ _ _ _ _ _ _ -_-..

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v .:. 9 9.,

.

16 .

. , .

> il

#-.'Beckman Model-4000 Automatic:Samele Chanser.'

: Well . Sci nti1lation Counter- Cali brati on Procedure.'

This test -is to determine the countins effiency(counts /drm) for 1-125. A- calibrated source of I-129 (ICN

~

~ Ra di oc hemi cal s, 77313 nominal a c tivi tv. O. 01 uCi)~is used. A-factor (F) used to convert counts to uCi is prerared as . f ollows:

!

-F~=_( A x t-) / ( Ct:- Cb )

g

to ber eiA=-uCi in the standard sourcet= countins timeCtenumber counts in time .-( t)Cb=backsround counts in time (t)

The. conversi on factor i s determined everv' time the system is.used to count wire test samples and is recorded alons with. test,

results.

F

f

,

Well Counter CalibrationLufkin Medical Laboratories

N R.C.313 I, item lib15-OCT-1980

L

m__ _________.__Il__._________._.__.__.'. _ . . . . _ _ _ . _ _ _ - _ _ _ _ _ _ . _ _ _ _ _ _ . __. .

M,ffdQ.-- ' '

. . - _ - - , . - _.

. - - _ - , - _ _

- %.

_ . . ;- %nqc o.

,\gh .. .

'-a

,ag'_ ; l ''' @\s' g fj : '-> '

~ Q M-q .. , .i

Nih - Survey 'I nstruder$UCali bt a ti on Check2

' " , ' . . .V1etoreen Model:491 THYAC w/ Pancake Probe.Model 489-110,

. - q --

.A); Mechanical) Check' .look for'1oose wirins, . PoorL electrical' connections ; battery corros4on, i nt ermi tta n t swi tc hi ns, ' asedbatteries,'etc.

.B) ' Operational check. operate , built in battery che'ck circui.t :and check' source.

'

C) Scale accuracy and.'s qal i bra ti on; constancy check: ThisJ ' procedure. veri fier ~ rrocer opera ti on of the Probe and 'ratemeter

ci r c ui t. Cai x br a ti o n .accurace is aef erenced to the strons sammacomponent of Ra-226 01 mm.- ~ P t ' fil tra ti on). The test is'done at' a

,.

nearby hosrital bY ' d ' R. Gisanti, Ph.D, usins? certifled sources''

rented from Radium Chemical;Comrany, N.Y.C., N. Y. - A sinsle 10heMi.n a Leaden shield (see drawins)'to define a2msm source is

broad' beam Usins distance and lead attenugters, a relection of,_

"exrosure rates can be rroduced at the detect'or Position'forcomparison wi th the mR/hr scale- o f- the ratemeter. Deviationsbeyond +-10%, of expected oxFosure rate are lossed and 'if foundsreater than +-20%'are cause for attemptins to adjust calibrationor. send'for repair.

scale msm Ra dist atten exrected a c c e p ta bl e

(mRfhf) 1cm) (cmPb) mR/hr ranse

O'- 20 10 70 NO 15 13.5 - 16.510 120 NO 5 .4.5 -- 5. 5

0-2 10 220 NO 1. $ i 1. '4 - 1. 610' 400 NO 0. 5 O.45 ' O.55-

O - O. 2 10 180 5. 6 O. 15 O.14- O. 1610 300 5. 6 0.05 0.'045- O.055

A los. of the tests is maintained for' c6mmission. R

I I nstrument Cali bration CheckS uf VeY

Lufkin Medical LaboratoriesN. R. C. 313 I, item' lib

I., 15-OCT-1980

-a _ _ - - . - . _ _ _ - , . - - - - - - - - ~ ~

- - ..

.. - _ _ - _ _ _ _ _ - _ - . - . - _ _ . . _ _ , _ _ _ _ - _ - . _ - _ . _ _ - _ -

,

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-PERSONNEL MON'ITORI.G''"'

',

LUFKIN MEDICAL' LABORATORIES- |0' '

>

, j'

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.Due'Eto - the l ow' quantites of radionuclides involved and- E

.t h e '- low enersies of Fhoton emission,' no' film 2badse'or otherLformW -- ' ~ o't t rersonnel: ' dose moni tori ns will - be ' used.

.

.

The'RI A oreration requests:authorizatiord f or oniv 4 ' mci'

total activity- on site at one time. It' is. used 'at ia ' rate of about~

'

2-mci'Per month maximum. ' T hi's :. q ua nti ty, and s'rveys made~ of the.u~

-' a'r ea , confirm, that. i t- . i's unlikely any individual'wi11' receive-' doses equal t'o or sreater thanithose' indicated i'n 10ECFR 20.101.

, ..

'The' need f or- Bi oa ssay has- been c o n s i d er e d,'. but the, ,

cmi nute . quanti ti es ..bei ns adorked with weish asainst this type ofe; monitorins:also. _ Good laboratory technique is+ emphasized:~

| '~

-1 ) no' ea ti ns, drinkins or smokins in lab-

2)no mouth Firettins "

| . .3)use sloves' when cl eanins L seills or ' decontaminate ns.j 4) wash hands before leavins for breaks, . lunch or home5)oheck for hand,. body contami na tion. wi th surveyinstrument6)1 ocalize ' work on bench7) work :over noneorous bench ' surf ace to facilitate cleanur8)use-posted containers for solid waste.9) frequent:< checks for work surface c on tami na ti o n.

i..

a

&

Personnel MonitorinsLuf kin Medical Laboratories

N.R.C.313 I, item 1515-OCT-1990

_ _ - - -__ _ _ - _ - -

- _ - _ _ _ _ _ _ _ _ _ _ - _ _ _ _ _

''. : o o.

.

RADIOWASTE DISPOSAL PROGRAMLUFKIN MEDICAL LABORATORIES

The RIA oreration makes use exclusively of short livednuclides (I-125 and Co-57). All tests involve aaueous, soluble

s u r er na ta n t s. The route chosen for disrosal it, therefore, thesanitary sewer system for the majority of activity and s t ora s e forradio-decay to handle the remainder No commercial ra di owa s t edisrosal service is used. _

After tests are comrleted, the rlastic tubes aredecanted imm e di a t ely into desisnated sinks The empty tubes arethen rinsed in water and " v or t e::: e d " to loosen and solublireremainins protein on walls. The tubes are rinsed esain anddissarded as non-radioactive refuse. Experimental determinationof activity after the washins erocess i ndi cates remai ni ns activi tyin tubes is equivalent to that found after 4 half-lives (8 months)

or more of stor ase of unwashed tubes.|

Disrosable rirettes, and other solid items contaminated

are bassed, labelled, da te d and ctored for decay a minimum of

three months. These sealed bass may be released to normal refuse| if no activity above backsround can be found usins a sensitive,

| thi n window survey instrument. Radiation labels are removed rrior| to release from storase. A record of bass removed from storase is| maintained for inspection.|

||

r

Radiowaste Disposal Prosram

Luf ki n Medi cal LaboratoriesN. R. C. 313 I, item 15

15-OCT-1980

. . ,.

_- .- _ -- , - _ - - _ _ _ _

,e' e 'l 1 .

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. 9. .,_

-,.+ ,.

. .

SURVEY. PROGRAM. LUFKIN-MEDICAL-LABORATORIES

1'

o Lufkin laboratories rrovides a thin window G-M. tyPG-

survey' i nstrument-(Vi c toreen THYAC ' III /498-110' Probe) for instantaccess by RIAstechnicians. Thi s i nstrument -15 usefu1Lfor muickly

'

moni torinsE hands and1 work sur faces.,

.Once- a . week the instrument is used to' survey all work

i rs and lo s i e t o nSPe L i o n'.-

-

m

Wire' test surveys of work surfaces, hands, instruments,cabinetc _and floors are taken once a month,usins alcohol' moistened-swabs which are ' counted in a -well type. scintillation countet'asainst; a calibrated 0.01 uCi I-129 source. A map of wipe Ltest-

' locations and- a los- of test :results converted t oi uCi _'are

maintained.for'insrection.'

The'storase area for. bassed: solid radio-contaminateditems'is located in the RIA. area and is also surveyed.

E f f'l u e n t 'monitorins 'Is limited.to records'of activity

rrocessed in the. normal : course of work and. records o f. water. consumption to i nsure compliance wi th' 10CFR20c 303.

There 'are no volatile radiati on- sources ~in use.

At' -6 month . i nterval s sthe ;RSO . will revi ew the'. records

beins keet.and resul ts of'al'l tests.

o

Survey Prosram

Lufkin Medical LaboratoriesN. R. C. 313 I, item 15

15-OCT-1900

_ _ _ _ _ - _ _ _ -

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DUTIES .0F: THE RADI ATION SAFETY OFFICER (RSO)'.

' LUFKIN MEDICAL' LABORATORIES',

fy t <

Lufkin Labs RIA' service.uses the. services of Dr. J. Ft4- Gisanti, ~ P h, D. to f ul fill ' the rol e of LRSO .on a Part time 1 basis.

The' duties of this~ position' include the ~ f ollowins:

'1): ereraration and maintenance of the 'BYeroduct Materials,

.

license.*

2) ereraration of erocedures to fulfill the conditi'on-and,.

"seiritLof' licensure, includins' records, surveys and -r o s ti n s . 'r e s ui r em e n t s.

' 3)' educational erosram on selsoted topics includins. radiation safety o

4) calibration'of survey instruments 'and measurinsx arearatus

5), risk evaluation.in"emersencY situations-; 6 ) . admi ni s tra tive control'over radiowaste manasement

.

DUTIES OF THE RADIATION SAFETY OFFICERLUFKIN MEDICAL LABORATORIES

N.R.C.313 I, item 1515-OCT-1980

__-__ _ _ _______- __ __ _ _ -

~ - ~ ~ ~ - ~ - ~ -

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+. -

.

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1,j be released ffrom Estor' se fwill .be striered of their [a

,"

'radiati on tass. and'~ recorded incthe storase l os.

EUsed countins-tubos, which make u r f t h'e bulk. ofH <

solid Ewastei 'are ' emptied intO marked sinks and rinsedwith water, .The tubes arn -"vortexed" -with- water Lto-remove; remainins. Protei n. . hound activi ty. on the wall s. !

The1 tubes are "then rinsed asain;and released into resular' |'

D buildins refuse.~ Larse volume di$rosal work will-be'done- )i' with sloved hands and wa terrroof. 'arron. -The- survey- !,

i ns tr'um e n t . .i s also used -to . detect s.i s ni f i ca n t - .;O . contamination on clothins or hands. Re,reated washins i

'<

with soar'and water will remove any'found. !

|.( -i$ E. POSTING REQUIREMENTS !

!"

i,

' The . N. R. C. . requires form NRC-3 .to' be i

L ' pr omi na ntiv : r o s te d. Pl ea's e look for i t on th'e wall . near I'

the fume-hood. Note that the actual' license is kert.in afile in'Mr. Coorer's office. . Areas in which radioactive,

materials are used or stored must; have " Radioactive i

L . Materials" rosters alertins personnel to that fact. || |

I

[ Ff PERSONNELIMONITORING-L

|Personnel dose monitorins devices are:not used {

at Luf kin Medical Labs'.RIA operation because the maximum !

external dose' rossible. is still far too low Et o resister -|oni these' d ev i c e s.' LGood laboratory technique. and {-consultation withi .the- RSO-'is your best method o.f |

|'Freventins.unintentioned intake of these material s.1

G. LIQUID WASTE. DISPOSAL'

L !1

Liquid . wastes'are'all. water soluble and may be ;

disposed of.at will in marked sinks.in the RIA area. .!

H. RECORDSt

The f ollowins records must ~ be' kert- in neatfashion and current for N,.R,C. insrection if necessary:

,

1

1) surface contami nati on surveys' (G-M i nstr ) |2) Wire test contamination surveys-3) results of countins,effiency chf.eks-(6 month

interval max.) for well counter. I

4) los of G-M survey instrument cal, checks (6 month 1'

interval max.)5) water usase f or entire buildins6) RIA kit rurchases7) Release of radiowaste from storase area.

L _ _ _ _ _ _. - _ _-- - ._ _ - _ ___-____ _ ___

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INSTRUCTIONS TO PERSONNELLUFKIN MEDICAL LABORATORIES

A. LABORATORY TECHNIQUE:

1) no eatins, dri nki n s or smokins in the l a b ora t ory.

2) no mouth rirettins is allowed3) use rubber slover for cleanins and decontaminationoeerations

|-4) try to Neer Work area localized.

| 5) minimize movement of radioacti'se materials within the

|area.6) wear lab c oa t or arron at all times in la b area.|

I 7) wash hands frequentiv, errecially before breaks, lunch

and home.8) use the survey instrument frequent 1v to look forcontamina tion on clothins, si:i n and work area.

B. SURVEY PROCEDURES FOR RADIOACTIVE CONTAMINATION:

| The RIA area work surfaces and retriserator areto be surveyed for surface contamination in two ways.

Throushout the day, the technician is requested tomoni t or bench surfaces and clean if necessary. Once aweek, a readi rs usins standard technique will be taken at

each of several locations in the RIA area and a record ofthese values will be kert for N.R.C. insrection. Once amonth alcohol moistened wires of these locations willalso be taken and counted in the well counter slons withthe standard source of I-129 these values will beconverted to uCi and recorded in a los.

C. MOVEMENT OF RADIOACTIVE MATERIALS WITHIN THE BUILDING

Ra di oa c tiv e shirments are to be brousht to theRIA area as received. Without authorization from Mr.Coorer or the Radiati on Safety Officer ( J. Gi san ti ) nora di oa c tive material s may be brousht out of the area for

storase or other reasons.

D. DISPOSAL OF SOLID RADIOWASTE

Oniv c o n tami na t e d or likely to be contaminatedarticles are disrosed of in the srecially marked " SOLID

RADIOACTIVE WASTE" containers. When full, the rlasticlinins bas is sealed and a " Radioactive Materials" ta s isa t ta c h e d i ndi ca ti n s: 1)"I-125, and 2) the da t e of

sealins. The bas is then transferred to the storasecabinet in the R1(a area These bass will be monitoredr eri o di cally by the RSO or desisnate and may be released,with their arrroval, to resular buildins refuse Bass to

. ._ _ ,.

,

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'

9 _ 9;. .

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,;;..

b . .

I. . GOOD LABORATORY. PROCEDURE:

a)'No'smokins, eatins.or dri nki ns i n L lab.,

b)'.Noc ri eetti ns . by . mouth

c) Use'sloves amd arron when.cleanins srills or-

.deicontamina ti ns_ an area,d) Wear" Lab c; oate) .L'ocali ze work - on the. bench, : avoid. movins ' adi oactive.rma t erial sf), Work over.non Porous' lab: bench surfa'ce to facili ta tes

cl eanur <in : event of Srill.J. s) Survey worksurface~ frequent 1v;for contamination,

h) Do not move' radioactive' materials outside'RIA area,

wi thout 's eeci fi c . authori za ti on.i) Report srills and eniersency conditfons-to'surervisorPrometly.

5

J. . EMERGENCY PROCEDURES...

.a) SPILLS-----

Seills of. RIA radiolabellsd compounds are not. life threatening. When a lerse - v ol um e spill- occursobtain- a fresh Plastic waste bas- and a surP1v- ofdi srosabl e towel s. Usins a sloved hand simply blot urLthe H quid! to dryness and thus minimize the spread of'c o n tami na ti on. Place each sehnt towel into -the Plasticbas. 'U si n s t h e G-M i n s tr um e n t, surveyothe spill area'for

c o ntami na ti o n. A -solution. of. detersent and a small scrub, . .

. brush mey be useful to loosen deposits so they may be.

blotted ur'with disrosable. towellins. Generally keerbl otti ns - or scrubbins motion toward the spill center to'minimire s pr ea d. Clean as necessary to brins G-Mindication to backsroundi Take a wire test samele of thesrill area and surrounding areas which may have receivedsplash. Count these- and record results as an entry in'the wire test los, Seal and. label the bassed absorbentmaterial and Place into the storase area for decay.

b)-ACCIDENTAL CONTAMINATION OF PERSONNEL CLOTHING, SKIN

t

Cl o thi ns thousht to be contaminated should beremoved and bassed for insrection by the RSO. Ski nsurface contamination may be reduced bY repeated washinswi th~ soar and' water Avoid surface abrasion. Prosress j

may be monitored usi ns the G-M survey instrument and a i

wir:e test mav also be done.

L.4; '

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H c)IACCIDENTAL~ INGESTION ~OFLRADiOACTIVE MATERIAL'

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L The . vast. maJ ot i ty of a c t i vil.y used in the RIAk

|: - lab . i s ~1odine-125; and- as 'such it is concentrated-p selectively' -by .the- body. in the- thyroid . s l a n d. -An[; a c ci-d e n ta l insestioni must. be rerorted immediately to the

P lab zueervisom Mr. Coorer. and -the 'RSO, D r. Gi sa n ti."

Tosether; thev: 'will .,try'Et o ' e s tima t e th e - a c ti Vi tY likely

'insested'and the course . ot acti on to . take. Quite asidefrom'fany' biohazard, . a survey of the neck area-may be"

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requestedLin a'hoseital|derartment--of nuclear medicine to.attempt; to ; 9uanti fy insested activi ty,

b lO PROCEDURE'FOR RECEIPT OF RADIOACTIVE SHIPMENTS.

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Packases c1 ways contain 9uantities which areL below.the'Tveef ~"A" Nuantity limit of - 10CFR20, 205 ( b ) .

.Therefore no special. monitorins is required. The-'

rackases are simely moved from the receivins area to' the'-RIA area,'insrected for external damase and riaced in'theRIA refrigerator'for storase. Damased rackases should bebassed before Placins into the refrigerator and ~ the RSO

I n o ti fi'e d. The damased rackase will be orened carefullyLand, surveyed forLcontamination before use.

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Instructions to RIA Personnel jLuf kin Medical Laboratories

N. R. C. 313 I item 1515-OCT-1980 j

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Fw= A80488 U.S. ATOMIC ENERGY COMMISSION Form Asesowed

, @s. REGISTRATION CRATIFICATL- IN Vf780 TESTING NE'*" "WITH EYPRODUCT MATERIAL UNDER GENERAL LICENSE

Seenies 31.1) g*of to CFR.31 === Mh a general lisense sashneleing phreklees elleken laborescries, med hosphals se passeus sensle smallthe inesmal e essereal ad=m steen ed she pactgeenstidos er seerial for de more fielcat er " ' - sense nos 6ne

** '* N hee InE FYM 'e'ce"eleed steenED's#M's$p*r*e'fN AR["Ye{"pNie's csis-

*.#me r

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smessde sair form he Mpfirade ser Uniend Senses Assmic Emersy e- - 't Washingson, D.C. 20545, Ateention: Direceor, Division ofMasariate Liteanias. A regisonensee asaber erill be assismed and n entidnted rety elForm AEC-481 avill be vernormed.

I. Please print or type wishin she shaded area, below, she name and address (including ZIP Code) of the registraat physician,clinicallabors-sery, or boepical for whom me for whidi abis regiestseien form is 6ted.

] M*"M

I Richard L. Reece MeDe )'

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J4 Lufkin n.m ,m1-1- --.-4..-

b 450eIRalliaT Arts Building" - 4'

* #y$Minneapolis, MinneggM J 5402 ,

-m | g - fw*-Y N= .Em1 ml y m am s g 2 W a m hJ

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/ 3. To be completed by the Atomic Emersy Co==3aaica

[ 2. I hemby apply for a regiesration number pursuant to Registration number: 05285 31.11, 30 CFR 31 for use of byproduct materials for U. S. ATOMIC ENE SION(ploese ebeca ear)

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g a. Myself, a ady licensed physicina authorised to die. 3pense drugs la abe practice of medicine. k 8 As,

.e . _%gga - . _ _ a ,gg,g,,g . - y- j, ,

*# ,* W ' SEP '3 m |os

0 c. W aboenamd besphal. BY: Clarence 11 bron ' 'e

u.unesissoar" ' er. .aan -

4. If place of use is dHfeest from addsees Inp sigileese p te address.

$ *

s #sne*:a8

$

[pCer inenetam: .

s I bereby eartify est:1 a. AH leformados is &is registruios cati 6cate is true and complew .

b. N sugie restions se radiaelos measuring lastrumente so carry out the sans for which bypeeduct material will be used under j'

the license to FR 31.11. & esses will be ; J f only by personnel competent la the use of the instrumsets and la sheed she bypresheet sensorials.' ' ' ,

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I, U *' I U N .U f M ** "g,, ,,

d. I beve reed and understead she provlsions of Section St.t1 of AEC regulations to CFR 31 (reprinted on abe reverse side of tble form)and I underocand shot the registrant is required to comply with those provisions as to all byproduct material which he receives, aceposseenes, uses, or transfers under abe general !! cense for which this Registration Certl6cate is 61ed with the Atomic Energy e--

paires

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!4:ss?c-o. A-si,es, ,or ,s w i

" NDai. Seotember 17, 1970 ny-

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Richard Le Reece, Mode, Director / Partnerp.4,a es.s a ,u. a reams. or ps,se. nue, oe

WaMW885.-14 U.a.C Seatten 1001: Act of June 25,194a; 42 Stat. 749; mahoe et a criminal e#ense to make a wNifuHy false statement er repre.eentoteen ps any esportment er egency of the lAnited States es to any metter within see jurtedictlen.

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O STANrOno UNivEnSi1v O*

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GRADUATE SCHOOL OF BUSINESS...

EDWARD A. K AUFMAN, M.D.,

Address Other Arnbee,,,

70 C Escondido Villaqe R.H.No.3. Stanford California 94305 Appieron~ (415) 324 9380 .'

Mmnesota 50208

Job Objective: General management and/or n.edical posihon in a chnir.al lahuratory or boahht%no industry.

Education:1978-1980 STANFORD GRADUATE SCHOOL OF BUSINESS

MBA Candidate,' June,1980. Course emphases in health care, finance, anddecision analysis.

19/0 1972 BOSTON UNIVERStiY SCHOOL Of MEhlCINE. Boston, MassachusettsM.D.. May,1972.

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1966 1970 UNIVER$1TY OF SOUTH DAKOT A SCHOOL OF MEDICINE. Vermation, South Dakot 1.B.S., rnedicine, May,1970. President, sophomore cla;s and Sto:.!ent Ana rican Medica:Association, South Dakota chapter. E ecutive Councd, South Dan ota St.no MW atSociety.

h 11968 STANFORD UNIVERSIT Y. Stanford Cahforma.A.B. Inology, June,1968. Bad oround m ruaihematics and i hemiso v. Stantord areAustria, 1907-1968.

Emerience: -

1979 pal HOLOGIST, Mary's Help Hospaal. Daly Cov. Cahf or nu.

* 1978 PAT HOLOGIST, Laboratory of Choic.il Mmhcine and Irernanoel St. Josenh'sHospital, Manka to. Minnauta.

1973 191/ PATHOLOGY RESIDENT, Mount Fion Hosintal and Medmit Ceraer San Francist.o.Cahfoinia. Anatomic and rhnical pathoknv r esufency woh special interests inohnical chemistry and laborator y managernent. Chief resident, 1976-1977

1973 1977 EMERGENCY ROOM PHYSICI AN, Cahfornia Ernergency Physicians. Oak lan<!,CahIornio, part hme.

19/?1973 ROT ATING INT ERN, Mount Zion Hosonal. San Francisco. Cahf ornia.

Licensure andCertificatic n: PHYSICI AN AND SURGEON, Cahfornia.1973. Mmnm.ou 19/8.

BOARD CERTIFIED in anatomic and thnical pathology by the Arnerican Boardof Patholoijy, May.1977.

f f L t (T,Y. Coiico" of Ainn n an Patholao ' h fo' ci m en So ". t c ul C ho n.al Pa n g,lona.p.Mif 0 Ma H a S: h W t', .!! l 'H h' = f all . i i n h '

Additional S aded voth f aanly t o the Sm ah P.n o n a:c .. int Cr ya c. 19 / / 19 /8 1 ton:s an'J AiinginIOr MDtiOn: t'IH husiasi, llam la ha 4 y si'f.d ot . I hisl y ( o 'f f thsn la'i h ht;!d at ia l /. Mat f st"j, t wo daur;h.

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f et s, ayfs tive and L le.

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CURRICULUM VITAE

Name: Joseph Robert Giganti,

Address: 1785 Taconite PointSt. Paul, Minnesota 55122

Phone Number: (612)452-4982

Birth Date: February 7, 1942

Marital Status: Married, 2 children

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Academic Training and Pertinent Experiencei

1960 - 1963 University of Maryland, College Park, MDCourse work in Chemistry, Physics, ZoologyMaj or: Zoology - Degree: B.S. June 1963

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1964 - 1966 University of Florida, College of Pharmacy, Gainesville, FLCourse work in pharmaceutical practice, formulations

physiological / pharmacological effect,of drugs.Major: Pharmacy - Degree: B.S.P., April 1966

1966 - 1967 University of Florida, Graduate School, Cainesv111e, FL,

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Course work in basic nature of radiation, radiobiology,health physics, rationale for calibration of teletherapy,diagnostic machines. Principle Instructors: Walter Maudr11,

- DSc (Advisor), Bill Dunavant, Ph.D., Fred Bruno, M.S.,Lt. Fitzgerald, Ph.D.

Major: Biophysics of Radiation - Degree M.Sc., December 1967Master's Thesis Title: A Digital Output Gao-Discharge Camera.

1968 - 1979 University of Minnesota, Graduate School, Minneapolis, MNCourse work in medical nuclear physics, dosimetry, radiation

biology, computer programming theory, e1cetronic circuit~

design, quantum mechanics, environmental radioactivity,biochemistry and other physical sciences. PrincipleInstructors: M.K. Loken, M.D., Ph.D. (Advisor), Fiaz M.Khan, Ph.D., (Advisor-2), D. Barber, Ph.D., O. Schmitt,Ph.D., E. Ackerman, Ph.D.

Maj or: Biophysics of Radiation - Degree: Ph.D., March 1979Ph.D. Thesis Subject: Investigation into ways of automating

the external beam teletherapy treatment planning processfor treating defined tumors. As part of this project, alarge computer program was written to automate techniqueThesis Title: An Interactive Procedure for Automating theSelection of Treatment Plans.

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Miscellaneous Awards1

1966 Graduation from University of Florida Suma Cum Laudae |j

|1966 Bristol Award for Excellence in Pharmaceutical Preparations ;

!Publications and Presentations '

|: A Practical Technique for Automating the Selection of Radiotherapy Treatment;

Plans (Abstr.) J.R. Giganti, F.M. Khan, Med. Phys. 6:349 (1979). |

Effect of Hyperbaric Conditions on 75 selenomethionine Distribution in the Rat.S

J.R. Giganti, D.L. Malejka, H.L. Cromroy (presentation at Society of Nuclear ,

Medicine Meeting, Lexington Kentucky) (1967). |!i

Membership in' Professional Societies

Kappa Psi (Pharmaceutical Fraternity),,

Rho Chi (Pharmaceutical Honor Society)'Phi Kappa Phi (Honor Society)American Association of Physicists in' medicine (national / regional)Health Physics Society

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Employment Experience>

1972 - 1980 President of Radimetrix, Inc., Medical Radiation Physics.(A small consulting firm providing radiological and healthphysics services to hospitals and physicians with the a,id of

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_*technical employees. Services include calibrations, site !

planning, external beam and brachytherapy dosimetry,. computerprogramming and others.)

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Outside Interests and Hobbies:

Sailing, model building, electronics, solar / wind power.

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