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Combined Spectral Domain Optical coherence tomography
(SD OCT) , Fluorescein angiography(FA), Indocyanine Green
Angiography (ICGA) and Autofluorescence (AF) features of
Posterior Uveitis
Dr Navneet Mehrotra
Dr Manish Nagpal
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Financial disclosure
Authors have no financial interest in any of theproducts used
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Purpose :
To correlate simultaneous FA, ICGA, AF andSDOCT characteristics in cases of posterioruveitis using Spectralis.
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Materials and Methods
128 eyes of 64 patients of posterior uveitisunderwent imaging using spectralis
Patients with different uveitis entities wereincluded like serpeginous like choroiditis, VKH
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Serpeginous choroiditis
Serpeginous like choroiditis
Multifocal choroiditis
VKH
Toxoplasma retinochoroiditis
Choroiditis mass
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FA characteristics
FA characteristics in case of choroiditis include -
- In early phase, new lesions block the backgroundfluorescence.
- In due course leakage of dye appears in and
around the active lesions- Staining in healed lesions
- Window defect in previously scarred lesions
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Fluorescein angiography
FA early phase
FA late phase
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Simultaneous
FA and ICG
FA ICG
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Simultaneous
FA and ICG
FA ICG
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Simultaneous FA and ICGFA ICG
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Simultaneous ICG and OCTICG OCT
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Simultaneous
AF and OCT
Pre treatment
Post treatment
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Results
33 eyes
Active phase confluenthypofluorescent lesions inICG
Resolution phase
segmentation of confluentlesions
Active phase
After treatment
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Simultaneous FA and ICG
Active phase
After treatment
FA ICG
FA ICG
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Results
21 eyes
Active phase
Peripapillary elevation in OCT
Simultaneous AF and OCT
AF OCT
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SimultaneousAF and OCT
Pre treatment
Post treatment
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Results
91 eyes
Active phase
Hypofluorescent dots in ICG
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Active area : ICG - OCT
Hyporeflectivity in choroidal region corresponding to dots in ICG
ICG OCT
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Simultaneous FA ICG and AF - OCT
Hyperautofluorescencecorresponds to thehypofluorescence inICG
FA ICG
AF OCT
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Results
12 eyes
Hyperfluorescent dots adjacent to disc in ICG
FA ICG
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Results
66 eyes
Reduction in hyperautofluorescence inresolving phase
Active phase After treatment
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Simultaneous AF and OCT
Pre treatment
Post treatment
AF OCT
AF OCT
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Simultaneous FA and ICG
Lesion size in ICG more than that seen in FA
FA ICG
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Simultaneous FA
and ICG
Decrease inhypofluorescentdark dotsfollowingtreatment in ICG
Pre treatment
Post treatment
FA ICG
FA ICG
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Follow up case ofserpeginous likechoroiditis
After 3 mnths
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Healed serpeginous like choroiditis
AF OCT
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Simultaneous FA and
ICG
Large choroidal vessels visible in ICG suggestive of healed choroiditis
periphery
FA
FA
ICG
ICG
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Simultaneous FA OCT of an active area
FA
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Conclusion
Simultaneous imaging helps in diagnosis andfollow-up of patients with posterior uveitic
diseases
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Thank you