XII Congress

of the European Federation

of Autonomic Societies

Wednesday 12 to Saturday 15 May 2010

Giardini Naxos – Taormina (Messina)

Sicily - Italy

PROGRAMME

WELCOME TO GIARDINI NAXOS-TAORMINA

Dear Colleagues,Giardini Naxos, located just a few kilometres from Taormina, was settled by the

people of Naxos, the first Greek colony in Sicily. It is now a fascinating mix of ancientpast, with its characteristic fishing village, and present with beautiful beaches and craftindustries with the production of terracotta, ceramics, and the famous ironmongery.Taormina, the pearl of Sicily, is unique in location and its urban form, and for this reasonhas become an outstanding international resort. The interwoven and exquisite architecturegives an enchanting atmosphere to this little town. You will enjoy a walk through thedense network of lanes interrupted by small squares, winding among the walls of the an-cient houses. The tourist nature of the town offers some delightful restaurants, cafes andice cream bars.

Ancient Greeks were famous for their proverbial hospitality; the same sense ofhospitality has always been a characteristic of Sicilians. I am sure you will experience iton the occasion of EFAS2010. We will do our best to make your stay an unforgettableexperience!

Benvenuti!

Giuseppe Vita

President of the Italian Autonomic Society

Chairman of the Local Organising Committee

Dear Friends and Colleagues,On behalf of EFAS, I would like to welcome all of you to Giardini Naxos-

Taormina. This 12th meeting of the European Federation of Autonomic Societies prom-ises to be one of the most successful meetings our societies have held so far.

We are most grateful to the President of the Italian Autonomic Society, ProfGiuseppe Vita, who is hosting the congress and has organized a splendid social program.I also want to thank all members of the International Scientific Committee, who wereinstrumental in organizing a very appealing scientific program.

The autonomic world is small and still diverse. Therefore, we are delighted towelcome representatives from the American Autonomic Society (AAS), from the Euro-pean Federation of Neurological Societies (EFNS) and from the International Societyof Autonomic Neuroscience (ISAN) with whom EFAS seeks a close relationship andjoint meetings. similar to the successful conferences held in cooperation in the past.

I am convinced that we will all have a scientifically thrilling meeting in GiardiniNaxos-Taormina and I am sure that our host, Giuseppe Vita, will show us much ofSicily’s charm.

Ciao and welcome to Giardini Naxos-Taormina,

Pietro Cortelli

President of EFAS

CONFERENCE COMMITTEE

International Scientific Committee

Pietro Cortelli - Bologna, Italy, Chairman

Alberto Albanese - Milan, Italy

Giovanni Barbara - Bologna, Italy

Luciano Bernardi - Pavia, Italy

J. Gert van Dijk - Leiden, Netherlands

José Ducla-Soares - Lisbon, Portugal

Jean Luc Elghozi - Paris, France

Max Hilz - Erlangen, Germany

Jens Jordan - Hannover, Germany

Heinz Lahrmann - Vienna, Austria

Christopher J. Mathias - London, UK

Giuseppe Micieli - Milan, Italy

Anne Pavy-Le Traon - Brest, France

Isabel Rocha - Lisbon, Portugal

Jean-Michel Sénard - Toulouse, France

Vincenza Spallone - Rome, Italy

Thomas Thomaides - Athens, Greece

Giuseppe Vita - Messina, Italy

David Vodusek - Ljubljana, Slovenia

Gregor Wenning - Innsbruck, Austria-

Wouter Wieling - Amsterdam, Netherlands

Local Organizing Committee

Giuseppe Vita - Messina, President AINV

Pietro Cortelli - Bologna

Francesca Del Sorbo - Milano

Rita Di Leo - Messina

Pietro Guaraldi - Bologna

Simona Maule - Torino

Giuseppe Pelliccioni - Ancona

Marcello Romano - Palermo

Wednesday 12 May 2010

Room Dionisio9.00-15.30 Master Class on TLoC and Syncope

Chairpersons: J.Gert van DijK, Wouter Wieling, Roland D. Thijs

9.00-10.30 Classification of TLOCG. van Dijk (Leiden, Netherlands)

Epidemiology of TLOCW. Wieling (Amsterdam, Netherlands)

Pathophysiology of syncopeR.D. Thijs (Leiden, Netherlands)

10.30-11.00 Break

11.00-12.30 Interactive case presentations

12.30-13.30 Lunch

13.30-14.30 Interactive case presentations

14.30-15.30 TLOC: evidence-based history taking W. Wieling (Amsterdam, Netherlands)

TLOC: initial evaluation and risk stratificationJ.G. van Dijk (Leiden, Netherlands)

How to organise a Syncope UnitR.D. Thijs (Leiden, Netherlands)

16.00-18.00 EFAS Council

16.00-18.00 Registration to EFAS 2010 Congress

Room Tindari A18.00-19.30 Symposium: Neurogenic Orthostatic Hypotension

(Unrestricted Educational Grant by Chelsea Therapeutics and Dainippon Sumitomo Pharma Co.Ltd)Chairpersons: Pietro Cortelli, Horacio Kaufmann

Physiopathology and classificationI. Biaggioni (Nashville, USA)

Present pharmacological treatmentsJ.M. Senard (Toulose, France)

New treatment including results from phase II and III studies of DroxidopaC.J. Mathias (London, UK)

19.30 Opening Ceremony

20.15 Welcome reception cocktail (Garden)

Thursday 13 May 2010

9.00-10.45 SESSION IAutonomic neuropathies: genetic, autoimmune, paraneoplasticChairpersons: Alberto Albanese, Jens JordanRoy Freeman (Boston, USA)

9.00-9.30 LECTUREAutonomic peripheral neuropathy: Recent advancesRoy Freeman (Boston, USA)

9.30-9.45 A rare case of genetically determined selective sympathetic adrenergic failureP. Guaraldi, G. Calandra-Buonaura, G. Pierangeli, V. Donadio,S. Capellari, R. Liguori, P. Cortelli (Bologna, Italy)

9.45-10.00 Volatile hypertension is a risk factor for renal failure in patients with familial dysautonomiaL. Norcliffe-Kaufmann, A. Voustianiouk, F. Axelrod, H. Kaufmann (New York, USA)

10.00-10.15 Autonomic dysfunction and heart involvement in transthyretin familial amyloidotic polyneuropathyR. Di Leo, A. Mazzeo, G. Di Bella, C. Stancanelli, A. Recupero, M. Russo,S. Carerj, G.Vita (Messina, Italy)

10.15-10.45 Chairpersons: José Ducla-Soares, Giuseppe VitaLECTURERole of the heat shock response in misfolding disorders of extracellulardeposition: The first model of familial amyloidotic polyneuropathy with involvement of peripheral and autonomic nervous systemsMaria J Saraiwa (Porto, Portugal)

10.45-11.45 Break with Poster vision (Room Hibiscus)

11.45-12.45 SESSION IIPain, migraine and ANSChairpersons: Pietro Cortelli, Heinz Lahrmann

11.45-12.15 LECTURECentral pain-Autonomic interactions (Valsalva Lecture)Eduardo Benarroch (Rochester, USA)

12.15-12.30 Relationship between sympathetic activity and pain intensity in fibromyalgiaF.Barbic, A. Diana, F. Casella, F. Perego, M. Borella, F. Dipaola, G. Costantino, P. Longhi, P. Rubin, V. Repetti, R. Furlan (Seriate, Tradate, Milano, Italy)

12.30-12.45 The red ear syndrome and migraine: the role of the parasympathetic system in a complex and intriguing clinical associationA. Compagno, V. Raieli, F. Brighina, D. Puma, M. La Vecchia, M. D’Amelio, S. Mangano (Palermo, Italy)

13.00-14.15 Lunch (Room Nettuno)

14.30-16.00 SESSION IIINeurogenic orthostatic hypotension, hypertension and other cardiovascular diseasesChairpersons: Luciano Bernardi, Isabel Rocha

14.30-15.00 LECTUREClinical relevance of 24-h blood pressure profileGianfranco Parati (Milano, Italy)

15.00-15.15 Comparison of different methods for measuring baroreflex sensitivity in 1409 subjectsL. Bernardi, G. De Barbieri, M. Rosengård-Bärlund, V.P. Mäkinen, C. Porta, P.H. Groop (Pavia, Italy; Helsinki, Finland)

15.15-15.30 Postural tachycardia in children and adolescents: What is abnormal?W. Singer, D.M. Sletten, T.L. Opfer-Gehrking, P.A. Low (Rochester, USA)

15.30-15.45 Tilt training decreases total peripheral resitance’s variance in patients with refractory neurocardiogenic syncopeS. Laranjo, M. Oliveira, C. Tavares, S. Raposo, V. Vaz-da-Silva,V. Geraldes, R. Ferreira, I. Rocha (Lisbon, Portugal)

15.45-16.00 Hypertensive pregnancies: a 35-year follow-up on cardiovascular regulation. Is the sympathetic activation still persistent? Y. Bergmann Sverrisdóttir, A.C. Collén, K. Manhem (Gothenburg, Sweden)

16.00-17.00 Symposium: Autonomic disturbances in Parkinson’s disease(Unrestricted Educational Grant by UCB, Lundbeck and Boeringher Ingelheim)Chairpersons: Alberto Albanese, Letterio Morgante

16.00-16.30 Non-motor symptoms of Parkinson’s diseasePaolo Barone (Napoli, Italy)

16.30-17.00 Treatment of autonomic disturbances of Parkinson’s diseasePietro Cortelli (Bologna, Italy)

17.15-22.30 Tour to TaorminaMeeting point in the lobby of Russott Hotel

Friday 14 May 2010

9.00-10.30 SESSION IVAutonomic control in diabetes and other metabolic disordersChairpersons: Jean-Michel Sénard, Vincenza Spallone

9.00-9.30 LECTUREThe gut to brain neural axis in the control of vascular and metabolic functionRemy Burcelin (Toulose, France)

9.30-9.45 Voluntarily paced breathing and postural stabilityA. Nicotra, G. De Barbieri, N. Guazzone, M. Bissa, M. Nava, M. Bejor, L. Bernardi (London, UK; Pavia, Italy)

9.45-10.00 Deep breathing corrects the blunted BRS even after 30 years of type 1 diabetesM. Rosengård-Bärlund, L. Bernardi, J. Holmqvist, G. De Barbieri, M. Mäntysaari, C.G. Björkesten, C. Forsblom, P.H. Groop on behalf of the FinnDiane Study Group (Helsinki, Finland; Pavia, Italy)

10.00-10.15 Retinal vessel analysis in hypercholesterolemic patients before and after LDL apheresisM. Reimann, S. Prieur, B. Lippold, S.R. Bornstein, H. Reichmann, U. Julius, T. Ziemssen (Dresden, Germany)

10.15-10.30 Cardiovascular responses to ingesting a popular energy drink in humansG. Yepuri, P. Sallin, R. Chikhi, E.K. Grasser, C. M. Brown (Fribourg, Switzerland)

10.30-11.00 Break with Poster’s vision

11.00-12.15 SESSION VEndocrine and autonomic responses to stressChairpersons: J.Gert van DijK, Massimo Pagani

11.00-11.30 LECTURENeural Regulation of endocrine and ANS responsesJames P. Herman (Cincinnati, USA)

11.30-11.45 Changes of blood pressure modulate human voice. Preliminary results and physiological mechanismsM.S. Dawid-Milner, J.C. Benítez-Montañéz, S.A. Díaz-Santamaría, J.A. Reyes-Bueno, A. Ruiz-Ruiz, F.J. Barón-López, R.M. Bermúdez de Alvear (Málaga, Spain)

11.45-12.00 Reduced heart rate variability and prolonged QT interval in patients withuncomplicated essential hypertensionS. Maule, V. Milazzo, S. Abram, V. Crudo, A. Iannaccone, F. Veglio (Turin,Italy)

12.00-12.15 Blood injection injury phobia and severe vagal symptoms in patients with sleep syncopeL. Busweiler, D.L. Jardine, C.M. Frampton, W. Wieling (Amsterdam, The Netherlands; Christchurch, New Zealand)

12.30-13.30 Lunch

13.30-14.30 Symposium: Multiple System Atrophy (Unrestricted Educational Grant by TEVA & ASTRA ZENECA, Austria)Chairpersons: Pietro Cortelli, Susan Düerr

13.30-14.00 MSA etiopathogenesis: lessons from genomic studies and transgenic modelsGregor Wenning (Innsbruck, Austria)

14.00-14.30 MSA: Clinical trial updateSusan Düerr (Innsbruck, Austria)

14.30-15.45 SESSION VICentral autonomic disorders: Parkinson’s disease and parkinsonismsChairpersons: Christopher J Mathias, Gregor Wenning

14.30-15.00 LECTURECentral autonomic control in humans: insights from neuroimagingHugo D. Critchley (Brighton, UK)

15.00-15.15 Progression of autonomic failure in MSA assessed by UMSARS-I subscale: a prospective 2-year follow-up survey by the EMSA-SGS. Düerr, M. Köllensperger, F. Geser, W. Poewe, G.K. Wenning, on behalfof the EMSA-SG (Innsbruck, Austria)

15.15-15.30 Functioning of the autonomic nervous system in patients with Huntington’s diseaseZ. Melik, K. Cankar, J. Kobal, M. Strucl (Ljubljana, Slovenia)

15.30-15.45 Effects of ANS stimulation on the central nervous system: an in vivo event related fMRI investigationA. Bassi, B. Basile, E. Macaluso, S. Strano, C. Caltagirone, P. Cortelli, M. Bozzali (Rome, Bologna, Italy)

15.45-16.15 Break with Poster’s vision

16.15-17.30 SESSION VIISleep & circadian rhythmsChairpersons: Pietro Cortelli, Jean Luc Elghozi

16.15-16.45 LECTUREEffects of poor and short sleep on glucose metabolism and obesity riskKarine Spiegel (Lyon, France)

16.45-17.00 Diurnal variations of blood pressure in postural tachycardia syndrome: dippers vs. non-dippersJ.J. Figueroa, D. Bott-Kitslaar, J.A. Mercado, J.R. Basford, P. Sandroni, W. Singer, M.J. Joyner, W.K.Shen, D.M. Sletten, T.L. Gehrking, J.A. Gehrking, P.A. Low (Rochester, USA)

17.00-17.15 Heart rate variability during nocturnal frontal lobe epilepsy seizures: a wavelet analysis approachG. Calandra-Buonaura, N. Toschi, P. Tinuper, F. Provini, F. Bisulli,I. Corazza, G. Barletta, P. Montagna, M. Guerrisi, P. Cortelli (Bologna, Rome, Italy)

17.15-17.30 Hypertension in peri- and post-menopausal women is related to sleep quality and mood alterationR. Silvestri, I. Aricò, G. Vita, R. Condurso, M.R. Bonsignore, A. Zito, T.F. Cardile, G. Mento (Messina, Palermo, Italy)

17.30-18.30 Symposium: Fabry disease(Unrestricted Educational Grant by Genzyme) Chairpersons: Max Hilz, Giuseppe Vita

17.30-18.00 Central nervous system involvement in Fabry diseaseW. Borsini, S. Buechner (Florence, Bozen, Italy)

18.00-18.30 Peripheral nervous system involvement in Fabry diseaseA. Toscano, A. Garufi, O. Musumeci (Messina, Italy)

18.30-19.00 EFAS General Assembly

20.30 Bus leaving to “A Massaria” Restaurant for a typical Sicilian dinnerMeeting point at 20.15 in the lobby of Russott Hotel

saTurday 15 May 2010

9.00-10.45 SESSION VIIINeurogenic bladder, sexual dysfunction and gutChairpersons: Giovanni Barbara, David Vodusek

9.00-9.30 LECTUREMale and female sexual dysfunctionMax Hilz (Erlangen, Germany)

9.30-9.45 Muscarinic and nicotinic acetylcholine receptors in mouse bladder afferent neurons and their expression profile in lumbosacral afferents in bladder outlet obstructionR. Nandigama, M. Bonitz, T. Papadakis, S. Möller, C. Illig, U. Schwantes,T. Bschleipfer, W. Kummer (Giessen, Bamberg, Germany)

9.45-10.00 Portal osmopressor mechanism linked to TRPV4 and blood pressure controlJ. McHugh, M. Appalsamy, S.R. Raj, A. Diedrich, J. Jordan, D. Robertson(Nashville, USA; Hannover, Germany)

10.00-10.15 Changes in enteric calretinin and calbindin immunoreactivities inrats with a unilateral lesion of the nigrostriatal pathwayM. Cervio, M. Colucci, B. Balestra, G. Levandis, C. Tassorelli, G. Nappi, S. Vigneri, M. Tonini, R. De Giorgio, F. Blandini (Pavia, Rome, Palermo, Bologna, Italy)

10.15-10.45 LECTURENeuro-immune interactions in the gastrointestinal tractVincenzo Stanghellini (Bologna, Italy)

10.45-11.15 Break

11.15-12.15 Lesson from basic science Chairpersons: Jean Luc Elghozi, Max Hilz

11.15-11.45 LECTURESympathetic control of regional circulationsClaude Julien (Lyon, France)

11.45-12.15 LECTUREThe Folk Medicine gene family and autonomic regulationDavid Robertson (Nashville, USA)

12.15-12.30 Young Participant Prize

12.30 Closing of the Congress

PosTer sessions (Room Hibiscus)

A. Syncope and other causes of transient loss of consciousness

Discussants: Roland Thjis, Wouter Wieling

1. Neurocardiogenic sympathetic dysfunction in postural tachycardia syndrome

C.A. Haensch, H. Lerch, S. Isenmann (Wuppertal, Germany)

2. Hypotension precedes bradycardia in the majority of patients with neurally mediated syncope irrespective of VASIS class

C. Schroeder, J. Tank, K. Heusser, A. Diedrich, F.C. Luft, J. Jordan (Berlin, Hannover, Germany; Nashville, USA)

3. Loss of consciousness in a patient with primary autonomic failure: not always hypotension

S. Servo, V. Milazzo, S. Maule, F. Veglio (Novara, Turin, Italy)

4. Prevalence of family history in patients with neurally mediated syncope

H.N. Holmegard, M. Benn, S. Haunsø, J. Mehlsen (Copenhagen, Herlev, Frederiksberg, Denmark)

5. Is it safe to tilt?

A. Grad, F. Benko, B. Meglič, F.F. Bajrovič, M. Baruca (Izola, Ljubljana, Slovenia)

6. Onset of sympathetic activation measured by quantitative sweat recording depends on VASIS subtype in vasovagal syncope

W. Struhal, A. Mismas, S. Hoedl, S. Schmidegg, H. Lahrmann, G. Ransmayr (Linz, Wien, Austria)

7. The importance of essential hypotension in syncope. A report of 877 patients. The Essential Hypotension Registry

L. Medina, M. Duque, W. Uribe, J. Aristizabal, J. Velasquez, M.A. Restrepo, A. Miranda, Y. Torres, J. Marin (Medellin, Colombia)

8. Familial postural tachycardia syndrome and Ehlers-Danlos syndrome type III: Clinical description and autonomic evaluation

V. Iodice, D.A. Low, R. Grahame, C.J. Mathias (London, UK)

9. Carotid sinus massage in the elderly: How do we quantify the response?

L. Brinth, J. Mehlsen (Frederiksberg, Denmark)

10. Vasovagal response to tilt table testing monitored by TASK FORCE in patients with syncope

T. Nišić, M. Platiša, S. Popović, V.D. Srećković, S. Damjanović (Belgrade, Serbia)

11. Autonomic nervous system scanning (Ansa Scan) and treatment of orthostatic intolerance and syncope

B. Milovanovic, M. Predic, A. Milovanovic, B. Milovanovic, T. Krajnovic, M. Ljubicic (Belgrade, Serbia)

12. Improving outcomes of severe disorders of consciousness

P. DeFina, J. Fellus, J. Thompson, M. Eller, R. Scolaro Moser, P. Frisina, P. Schatz, J. DeLuca, M. Zigarelli-McNish, K. Fallahpour, C. Prestigiacomo (West Orange, USA)

B. Testing ans function

Discussants: Walter Struhal, Thomas Thomaides

13. Preserved sympathetic and parasympathetic baroreflex in patients with continuous flow left ventricular assist devices

J. Tank, K. Heusser, C. Rasche-Schuermann, D. Malehsa, C. Bara, J. Jordan, M. Strueber (Hannover, Germany)

14. Importance of the choice of the tachogram length and period during heart rate variability determination

C.C. Grant, M. Viljoen, D.C. Janse van Rensburg, P.S. Wood (Pretoria, South Africa)

15. Non-invasive determination of baroreflex open-loop gain in man

B. Fiser, N. Honzikova, E. Zavodna, Z. Novakova, J. Moudr (Brno, Czech Republic)

16. Heart Rate Variability analysis through wavelet decomposition: validation and new perspectives

N. Toschi, I. Corazza, G. Barletta, A. Cecere, G. Calandra-Buonaura, M. Guerrisi, P. Cortelli (Rome, Bologna, Italy)

17. Age-dependent modulation of baroreflex sensitivity and spectral parameters during autonomic testing

M. Reimann, C. Friedrich, J. Gasch, H. Reichmann, H. Rüdiger, T. Ziemssen (Dresden, Germany)

18. Tilting speed affects the outcome of head up tilt table test

M. Kirbis, B. Meglic, A. Grad, F.F. Bajrovic (Ljubljana, Izola, Slovenia)

19. Haemodynamic responses to exercise and orthostatic stress in the postural tachycardia syndrome and vasovagal syncope

I. Skeavington, K. Bleasdale-Barr, J.C. Sanchez-Manso, D.A. Low, C.J. Mathias (London, UK)

C. neurogenic orthostatic hypotension and other cardiovascular diseases

Discussants: J. Gert van Dijk, Simona Maule

20. Initial or typical orthostatic hypotension? A preliminary report on clinical questionnaire

M. Baruca, B. Meglič, F. Benko, S. Antonić, F.F. Bajrović, A. Grad (Ljubljana, Slovenia)

21. Correcting vegetative imbalance in patients with chronic heart failure

I. Lukyanova (Saint-Petersburg, Russia)

22. Prevalence and correlates of orthostatic hypotension in a cohort of hypertensive patients

S. Maule, S. Totaro, E. Testa, V. Milazzo, S. Abram, V. Crudo, L. Angelici, F. Veglio(Turin, Italy)

23. Baroreflex sensitivity during orthostatic stress in patients with lone paroxysmal atrial fibrillation

M. Oliveira, S. Laranjo, C. Tavares, V. Vaz-da-Silva, V. Geraldes, S. Silva, R. Ferreira, I. Rocha (Lisbon, Portugal)

24. What do patients with classical and initial orthostatic hypotension, without an identifiable cause have to teach us? The Essential Hypotension Registry. Description of the population and the blood pressure measurements

L. Medina, W. Uribe, J. Marin, J. Aristizabal, J. Velasquez, A. Miranda, Y. Torres, M.A. Restrepo, M. Duque (Medellin, Colombia)

25. The Essential Hypotension Registry. Rationale for the blood pressure classification and the importance of the stress response

L. Medina, M. Duque, J. Marin, J. Aristizabal, J. Velasquez, A. Miranda, Y. Torres,M.A. Restrepo, W. Uribe (Medellin, Colombia)

26. Is glucose metabolism (HOMA and the relation: 2 hours postprandial plasma glucose / fasting glucose) different between blood pressure groups? The Essential Hypotension Registry

L. Medina, M. Duque, W. Uribe, J. Aristizabal, J. Velasquez, M.A. Restrepo, A. Miranda, Y. Torres, J. Marin (Medellin, Colombia)

27. The Essential Hypotension Registry. Blood pressure at the office and at 24 hours ambulatory monitoring is different between groups of essential hypertension, normotension and essential hypotension

L. Medina, M. Duque, W. Uribe, J. Aristizabal, J. Velasquez, M.A. Restrepo, A. Miranda, Y. Torres, J. Marin (Medellin, Colombia)

28. Evaluation of quality of life in younger patients with neurogenic orthostatic hypotension

J.L. Gilden, D. Vahedi, A. Nuygen, S. Ubhayakar, S.B. Maineni (Chicago, USA)

29. Orthostatic test in primary hypertension

F.Z. Milouk, S. Aboudrar, Y. Radjab, L. Coghlan, H. Benjelloun (Rabat, Ifrane, Morocco)

30. Cerebral autoregulation remains intact during postprandial blood pressure reductions in older normotensive and treated hypertensive individuals

B. Grobéty, G. Yepuri, J.P. Montani, C.M. Brown (Fribourg, Switzerland)

D. ANS and basic sciences

Discussants: Claude Julien, Anne Pavy-Le Traon

31. Sympathetic control of the cerebral vasculature in rats

A. Revel, V. Oréa, B. Chapuis, C. Barrès, C. Julien (Lyon, France)

32. Influences of neutrophilic airway inflammation on sympathetic vasomotor tone

J. Tank, K. Heusser, H. Biller, W. Koch, A. Diedrich, N. Krug, J. Jordan, J. Hohlfeld(Hannover, Germany; Nashville, USA)

33. Glial derived neurotrophic factor (GDNF) mediated regulation of airway sensory nerves in allergic asthma

C. Nassenstein, B.J. Undem (Baltimore, USA)

34. Tracheal brush cells are cholinergic sensory cells (with neural connection)

G. Krasteva, T. Veres, T. Papadakis, P. Hartmann, C. Mühlfeld, K. Schlieker, K. Hans, Y.N. Tallini, A. Braun, I. Ibanez-Tallon, M.I. Kotlikoff, W. Kummer (Giessen, Berlin, Germany; New York, USA)

35. How is the autonomic nervous system, as measured by heart rate variability, influenced by physical training?

C.C. Grant, M. Viljoen, D.C. Janse van Rensburg, P.S. Wood (Pretoria, South Africa)

36. Effects of ANS stimulation on the brain engaged by cognitive task: an in vivo

fMRI investigation

A. Bassi, B. Basile, E. Macaluso, S. Strano, P. Cortelli, C. Caltagirone, M. Bozzali (Rome, Bologna, Italy)

37. The influence of acute mental stress on cardiac and vascular activity in men and women

N. Potocnik, Z. Melik, K. Cankar, V. Starc (Ljubljana, Slovenia)

E. Autonomic dysfunction in metabolic disorders and neuropathies

Discussants: Max Hilz, Pietro Guaraldi

38. Cardiovascular autonomic reflexes in type 2 diabetes

S. Aboudrar, S. Jbira, F.Z. Milouk, Y. Radjab. L. Coghlan, H. Benjelloun (Rabat, Ifrane, Morocco)

39. Autonomic profile of hypertensive and type 2 diabetes patients

N. Azzouzi, S. Aboudrar, F.Z. Milouk, Y. Radjab. L. Coghlan, H. Benjelloun (Rabat, Ifrane, Morocco)

40. The relationship between the spectral-peak frequency in the range of frequencies between 60 and 120 mHz in cross-spectra of blood pressure and heart rate fluctuations and baroreflex sensitivity in young diabetics and healthy controls

N. Honzikova, M. Javorka, I. Tonhajzerova, K. Javorka, A. Krticka, B. Fiser, P. Honzik (Brno, Czech Republic; Martin, Slovak Republic)

41. Diagnostic characteristics of heart rate cardiovascular tests in assessing cardiovascular diabetic autonomic neuropathy

R. Morganti, C. D’Amato, T. Fedele, S. Rotella, L. Cacciotti, C. Greco, V. Spallone (Rome, Italy)

42. LDL apheresis improves deranged cardiovagal modulation in hypercholesterolemic patients

M. Reimann, U. Julius, K. Haink, B. Lippold, S. Tselmin, S.R. Bornstein, H. Reichmann, H. Rüdiger, T. Ziemssen (Dresden, Germany)

43. Diagnosis of autonomic neuropathy in liver cirrhosis

S. Servo, V. Milazzo, S. Abram, V. Crudo, S. Maule, F. Veglio (Novara, Turin, Italy)

44. A case of autonomic neuropathy associated with paraneoplastic cerebellar degeneration with positive anti Hu-antibodies and small cell lung cancer

S. Hödl, W. Struhal , M. Guger, S. Schmidegg, G. Ransmayr (Linz, Austria)

45. Transthyretin familial amyloidotic polyneuropathy: a five-year follow-up in a population from Southern Italy

R. Di Leo, A. Mazzeo, G. Di Bella, C. Stancanelli, A. Recupero, M. Russo, S. Carerj, G. Vita (Messina, Italy)

46. Influence of impaired sympatho-vagal balance on survival of ALS patients

S. Pavlovic, B. Milovanovic, Z. Stevic, M. Predić (Belgrade, Serbia)

F. Central autonomic disorders

Discussants: Francesca Del Sorbo, Gregor Wenning

47. Heart rate variability in 100 patients with Parkinson’s disease

A. Katagiri, M. Asahina, Y. Akaogi, Y. Yamanaka, Y. Fijinuma, T. Fukushima,S. Kuwabara (Chiba, Japan)

48. Alpha-synuclein linked central autonomic degeneration: experimental evidence

S. Stemberger, W. Poewe, G.K. Wenning, N. Stefanova (Innsbruck, Austria)

49. Neurogenic orthostatic hypotension in multiple system atrophy: can it be treated by home orthostatic training?

Y. Kilic, S. Koeppen (Essen, Germany)

50. An instantaneous time-frequency methodology applied to evaluation of blood pressure changes during HUT of multiple system atrophy patients

C. Tavares, S. Laranjo, M. Santos, R.C.M. Martins, I. Rocha (Lisbon, Portugal)

51. Heart rate variability in infants with central nervous system pathology

B. Bjelakovic, S. Ilic, L. Dimitrijevic, B. Milovanovic, G. Kostic, L. Bjelakovic, S. Lukic (Nis, Belgrade, Serbia)

52. A history of mild traumatic brain injury is associated with subtle sympathetic cardiac dysfunction upon orthostasis

M.J. Hilz, P. DeFina, S. Anders, C.J. Lang, E. Pauli, S. Flanagan, S. Schwab, H. Marthol (Erlangen, Germany; New York, USA)

G. Skin-ANS interactions

Discussants: Rita Di Leo, Alessia Nicotra

53. Clinical assessment of sudomotor function: relationship between sympathetic skin response and sweat production

A. Nicotra, A. Kuppuswamy, C.J. Mathias, P.H. Ellaway (London, UK)

54. Skin-sympathetic and cardiovascular dysfunction in neurological disorders

M. Asahina, Y. Akaogi, Y. Yamanaka, T. Fukushima, Y. Fujinuma, A. Katagiri, S. Kuwabara (Chiba, Japan)

55. Central and peripheral autonomic failure in cold induced sweating syndrome type 1

R. Di Leo, M. Nolano, H. Boman, G. Pierangeli, V. Provitera, Per M. Knappskog, P. Cortelli, G. Vita, C. Rodolico (Messina, Telese, Bologna, Italy; Bergen, Norway)

56. Cold perception and autonomic nervous system activity during local coldexposure at different temperatures

M. Music, K. Cankar, Z. Finderle (Ljubljana, Slovenia)

57. A family affected by primary focal hyperhidrosis not linked to known loci

F. Del Sorbo, E.M. Valente, G. De Joanna, F. Brancati, G. Lauria, A. Albanese (Milan, Rome, Napoli, Italy)

58. Dorsal paroxistic sweating: A case report

M. Santos, V. Gonçalves, A. Nabais, M. Laia, A. Sagarribay, M. Mafra, I. Rocha (Lisbon, Portugal)

H. Sleep and circadian shythms

Discussants: Giulia Pierangeli, Lia Silvestri

59. Grade I hypertension: evaluation of sleep structure and periodic limb movement syndrome (PLMS)

G. Pierangeli, D. Grimaldi, R. Vetrugno, F. Provini, G. Barletta, P. Cortelli(Bologna, Italy)

60. Circadian, time and state-dependent control of body core temperature is normal in narcolepsy with cataplexy

D. Grimaldi, G. Pierangeli, P. Agati, C. Franceschini, P. Guaraldi, G. Barletta, S. Vandi, G. Plazzi, P. Montagna, P. Cortelli (Bologna, Italy)

61. Wavelet analysis of heart rate changes before ictal asystole in a patient with nocturnal seizures

G. Calandra-Buonaura, N. Toschi, F. Provini, F. Bisulli, I. Corazza, G. Barletta, P. Montagna, M. Guerrisi, P. Cortelli, P. Tinuper (Bologna, Rome, Italy)

62. Prospective evaluation of autonomic functions in patients with obstructive sleep apnea syndrome (OSAS) treated by continuous positive air-ways pressure (CPAP) during sleep

J. Galuszka, P. Zmeškal, M. Táborský, I. Buriánková, M. Hobzová, K. Langová (Olomouc, Czech Republic)

63. Circadian neurovascular swing: a model of chronobiological dissynchrony from hypertension and sleep disorders to cerebrovascular disease

G. Mento, R. Condurso, I. Aricò, C. Casella, R. Silvestri (Messina, Italy)

GENERAL INFORMATION

Congress venueRussott Hotel

Viale Jannuzzo, 47 - 98035 Giardini Naxos (ME)

The hotel is in a strategic position overlooking the Ionian Riviera, not far from the mostexclusive places in Sicily such as Taormina, the heart of the island’s tourist trade. It is reached by the A18 motorway (exit “Giardini Naxos”), the main SS114 road (“Orien-tale Sicula”) about 50 km from Catania Airport (“Fontanarossa”) or by rail, arriving atthe railway station of Giardini Naxos-Taormina.Naxos, the first Greek colony in Sicily, was founded in 735/734 BC by the Athenians, orperhaps Chalcidians, general Teochles, and soon became the first connecting port be-tween Greece and its colonies. It is believed that when Greeks first landed in the bay,they erected an altar to Apollo Archégetes, protector of distant travellers. Surroundedby luxuriant vineyards and olive groves, the city rapidly grew into a centre of religious pil-grimages, thus becoming increasingly affluent.The city adopted the current name of “Giardini Naxos” in 1978, when Naxos was addedto Giardini to commemorate the first Greek colony. Located on the sea level, in a bayrunning from Capo Taormina and Capo Schisò, the famous volcanic peninsula on whichNaxos is situated has become one of the most renowned tourist destinations in Italydue to its geographical position. Today the city is surrounded by nature, only a short dis-tance away from River Alcantara natural reserve, and dominated by Mongibello, the fa-mous Etna volcano; Giardini Naxos is less than an hour drive from Catania’sFontanarossa Airport; the city offers several train connections and can be reached bycar via the A18 motorway from both Catania and Messina, which are only about 40 Kmaway.Giardini Naxos extends over a surface of 5.39 Km, with a population of 8.695. The city’seconomy, once based upon craftsmanship, agriculture and fishing, now relies ontourism, offering numerous restaurants, bars, lidos and over 50 hotels . Every yeartourists choose Giardini Naxos to spend a relaxing holiday surrounded by natural beau-ties and history. Today one can admire the remains of the ancient city and walk throughthe 10-hectare Archaeological Park and visit the annexed Naxos Museum. Nowadays,Giardini Naxos is one of the most important tourist destinations nationwide, with thou-sands of visitors from all over the world.

Language

The official language of the Congress will be English

Scientific Information

The presenting authors of oral communications must submit the powerpoint file 20 minbefore the start of the session. Time is 10 min + 5 min for discussion.Poster presenting authors are asked to mount their posters on Wednesday afternoon12 May 2010, prior to the opening ceremony. They should remain on display the whole

conference. The author must be present near the poster for discussion on Thursday 13 May, 10.45-11.45 (groups A-C-E-G) and Friday 14 May, 10.30-11.00 (groups B-D-F-H).Make sure to remove the poster from the board after the conference. The Congress staffwill remove posters not taken down on time.

Slide Centre

Computer projection only shall be available in all rooms. No slide projectors will be avail-able in the conference rooms and therefore it will not be possible to connect laptops toslide projectors. Speakers are invited to deliver their Power Point presentations to theSlide Centre on floppy disk, Cd-Rom or USB memory, saved with the speaker’s name.For images, please use extensions .gif or .jpg. For any other extension type or very largefiles, please contact the Organizing Secretariat. Each speaker shall collect their technicalmaterial at the end of the session, or at the latest at the end of the day. The Organizing Secretariat accepts no responsibility for any lost audio-visual materialthat was not collected or left unattended.

Internet point

Computers will be at participants disposal for internet access.The card for connection can be purchased at the hotel reception.

CME Accreditation

CME Accreditation has been requested to the Italian Ministry of Health in relation withthe Italian Continuing Medical Education program (CME) and to European AccreditationCouncil for Continuing Medical Educational (EACCME).

Certificate of attendance

At the end of the Congress, a certificate of attendance will be issued to all registeredparticipants, based on their actual attendance to course sessions and only by personalbadge presentation.

Variations

The Scientific and the Organizing Secretariats reserve the right to make whatever changeto the program they deem necessary for scientific and/or technical reasons, in compli-ance with Ministry regulations on CME credits.

Organizing Secretariat

Lisciotto Turismo srl – Via Camiciotti, 8 – 98123 MessinaPhone +39 090 29 82 262 – Fax +39 090 29 29 890E-mail: meetings@lisciotto.it – Web-site: www.lisciottoviaggi.it

SOCIAL PROGRAMME

Wednesday, May 12th 2010Welcome reception cocktail at Russott Hotel Garden

Thursday, May 13th 2010Tour to Taormina

Meeting point at 17.15 in the lobby of Russott Hotel.

Friday, May 14th 2010 Typical Sicilian dinner at “A Massaria” restaurant

Bus leaving at 20.30. Meeting point at 20.15 in the lobby of Russott Hotel.

RUSSOTT HOTEL CONGRESS CENTER

TINDARI A EFAS CONGRESS

DIONISIO TEACHING COURSE

HIBISCUS POSTER SESSION

NETTUNO COFFEE BREAKS AND LUNCHES

CORDARI SLIDE CENTER & INTERNET POINT

CIRCE ORGANIZING SECRETARIAT DESK

centro stampa universitario

THANKS TO OUR SPONSORS

ThanKs To our sPonsors