Annual Research Report 2015

Department of Surgery Odense University Hospital

List of Contents

Research Section ............................................................................................................................................ 1

Introduction ...................................................................................................................................................... 2

Research Council ............................................................................................................................................ 2

Adjunct Professors ........................................................................................................................................... 3

Associate professors ....................................................................................................................................... 3

Post.doc.’s ....................................................................................................................................................... 3

PHD projects finished in 2015 ......................................................................................................................... 4

PHD Students .................................................................................................................................................. 4

Physicians involved in research....................................................................................................................... 5

Research active Medical Students .................................................................................................................. 6

Research active Nurses ................................................................................................................................... 6

Other scientific staff ......................................................................................................................................... 7

Research Organization .................................................................................................................................... 8

Presentation of Sections and their main Research areas ............................................................................... 9

Research related procedures & techniques .................................................................................................. 11

Scientific publications (peer reviewed) .......................................................................................................... 12

Posters/Oral presentations ............................................................................................................................ 14

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RESEARCH SECTION

Head of Research

Professor Niels Qvist

G0 Section/G2 Section

Professor Michael Bau Mortensen

G1 Section

Professor Claus Hovendal

G1 Section

Adjunct professor George B. Hanna, MD, FRCS, MErgS, Academic

Surgical Unit, St. Mary’s Hospital, London, UK.

G1 Section

Adjunct professor Lars R. Lundell, MD, PhD, Centre for Digestive Diseases, Karolinska University Hospital, Huddinge, Stockholm, Sweden. G1 Section

Professor Gunnar Baatrup

G2 Section

Adjunct professor Robert Steele, MD, FRCS, MErgS, Head of the Cancer Research Unit at Dundee University and Chairman of Colorectal Society of Great Britain G2 Section

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INTRODUCTION

The Department of Surgery, Odense University Hospital, diagnose and treat patients with congenital malformations, benign and malignant diseases in lower and upper gastrointestinal system. The department is divided into the following sections:

1. Management.

2. Research Section.

3. Clinical Sections:

• G0 Section (Pediatric surgery).

• G1 Section (Upper GI surgery).

• G2 Section (Lower GI surgery).

• G3 Section (General surgery).

• G4 Section (Emergency surgery).

RESEARCH COUNCIL

The Department of Surgery has a Research Council which support the Research Section. All major research

projects and PhD studies are approved by the Research Council before study initiation.

MEMBERS OF THE RESEARCH COUNCIL:

Claus Christian Vinther, Chief Consultant, MPM

Susanne Barren, Senior Nurse, MPG

Claus Hovendal, Professor, Professor, MD, DMSc

Michael Bau Mortensen, Professor, MD, DMSc, PhD

Niels Qvist, Professor, Professor, MD, DMSc

Gunnar Baatrup, Professor, MD, DMSc

Helen Schultz, Post.doc., PhD

Lars Rasmussen, MD, G0 Section leader

Torsten Pless, MD, G1 Section leader

Per Vadgaard Andersen, MD, G2 Section leader

Jesper Bjerg, MD, G3 Section leader

Marianne Kirstine Thygesen, Assistant Professor, PhD

Mark Bremholm Ellebæk, MD, PhD

Pia Rosenkold, Research Secretary

Tanja Sotiris Millinge, Research Secretary

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ADJUNCT PROFESSORS

G1 SECTION

Professor Lars R. Lundell, MD, PhD, Section for upper GI Surgery, Centre for Digestive Diseases,

Karolinska University Hospital, Huddinge, Stockholm, Sweden.

Inaugural seminar: June 10, 2015.

Professor George B. Hanna, MD, FRCS, MErgS, Academic Surgical Unit, St. Mary’s Hospital,

London, UK.

Inaugural Seminar: September 24, 2015.

G2 SECTION

Professor Robert Steele, MD, FRCS, MErgS, Head of the Cancer Research Unit at Dundee

University and Chairman of Colorectal Society of Great Britain (to be appointed June 6th 2016).

ASSOCIATE PROFESSORS

G1 SECTION

Alan Ainsworth, consultant, MD, PhD

G2 SECTION

Marianne Kirstine Thygesen, MD, PhD

G3 SECTION

Jesper Durup, consultant, MD, PhD

POST.DOC. ’S

G2 SECTION

Morten Kobæk-Larsen, post.doc., PhD

Helen Schultz, post.doc, PhD

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PHD PROJECTS FINISHED IN 2015

Mark Bremholm Ellebæk: Topical microdialysis in early detection of complications after

gastrointestinal surgery.

Mie Dilling Kjær: Ileal pouch-anal anastomosis in ulcerative colitis. Functional outcome, fistula,

sexuality and the effect of TNF-α blockade in chronic pouchitis.

PHD STUDENTS

G0 SECTION

Anne Marie Jelsig: Hamartomatous Polyps - A Clinical and Molecular Genetic study.

Kirsten Risby: Congenital Abdominal Wall Defects. Surgical Technique, Postoperative Surveillance

and Long term Outcome.

Nina Højer Hansen: Morbus Hirschsprung in children and adults - Functional result after surgery,

QoL and comparative proteome analysis of mucosa in normal and affected colon.

Thomas Bjørsum-Meyer: Long-term follow-up in patients with anorectal malformations.

G1 SECTION

Ole Steen Bjerring: Endoscopic Ultrasound (EUS) and PET-CT based follow-up of patients radically

resected for cancer of the oesophagus, stomach or pancreas.

Signe Bremholm Ellebæk: Randomized study evaluating the effect of laparoscopic ultrasonography

during laparoscopic resection of patients with colorectal cancer.

Michael Bruun Nielsen: Cancer-associated fibroblasts and stellate cells: potential for a change in

pancreatic cancer treatment?

Nicolaj Marcus Stilling: Epidemiology of colorectal liver metastases and a new method for response

evaluation following chemotherapy in patients with CRC-LM (PhD application submitted).

Martin Graversen: Pressurized intraperitoneal Aerosol Chemotherapy (PIPAC) in patients with

peritoneal carcinomatosis. (PhD application submitted).

G2 SECTION

Ditte Gommesen: Perineal tear infection (Perineal Wound Healing).

Anne Marie Jelsig: Hamartomatose polyps - a study of the clinical and molecular genetic background

Rasmus Krøijer: Colon Capsule Endoscopy of immunochemical fecal occult blood test (IFOBT)

positive individuals in a national colorectal cancer screening program.

Karam Faiq Bashir Sørensen: Anorectal abscesses and complex fistula-in-ano (PhD application

submitted).

Issam Al-Najami: PUMK-DECT, Preoperative evaluation of meso-rectal lymph nodes with dual

energy-CT.

Minna Riishede: Ultrasonography in Acute Patients in the Emergency Department.

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PHYSICIANS INVOLVED IN RESEARCH

G0 SECTION

Lars Rasmussen

Mark Bremholm Ellebæk

G1 SECTION

Claus Fristrup

Alan Patrick Ainsworth

Ole Steen Bjerring

Torsten Pless

Michael Hareskov Larsen

Signe Bremholm Ellebæk

Martin Graversen

Nicolai Marcus Stilling

Helene Würtz

Christian Lolle Nørregaard

Niels Bjørn

Mark Jakobsen

Rasa S. Pedersen

Susanna Pedersen

G2 SECTION

Niels Buch

Thomas Kolbro

Rozy Eckardt

Søren Salomon

Jesper Clausen Nielsen

Panteha Khodadadeh

Kristine Cederstrøm Larsen

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RESEARCH ACTIVE MEDICAL STUDENTS

G1 SECTION

Joakim Knut Meidell

Anja Rosenlund Andersen

Rikke Brandslund

Martin Hangaard

Sevim Özden

Stella Justin Wilfred

Chirin Khalaf

Viktoria Benedicte Vejen Norstedt

G2 SECTION

Katrine Kristensen

Sabrina Valentin Thomsen

Pernille Kock Grave

Christian Dibbern

Morten Frederiksen

Carl-Philip Peter Rancinger

Emelin Spolen

Rasmus Emely Pettersson

Søren Rosenlund Petersen

Marcus Andersson

RESEARCH ACTIVE NURSES

G1 SECTION

Vibeke Gye

Malene Kaas Larsen

Maria Simonsen

Susanne Petersen

Ulla Krogstrup Tecedor

Helga Roued (Dietitian)

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G2 SECTION

Pernille Marie Vinifred Holm

Christina Petersen

Jane Holt

Pernille Mahnfeldt

Margit Ibsen

Helen Schultz

OTHER SCIENTIFIC STAFF

Jens Baelum, MD

Rie Overgaard Jensen, MD

Pia Rosenkold, Management Secretary

Tanja Sotiris Millinge, Research Secretary

Darley Petersen, Research Secretary

Jette Bang Hedelund, Research Secretary

Helle Kofoed Jensen, Economic staff

Camilla Kloster Andreassen, Economic staff

Maria Magdalena Buijs, Research assistant

Erik Sören Halvard Hansen, Student Assistent

Line Grønbæk Andersen, Student Assistent

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RESEARCH ORGANIZATION

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PRESENTATION OF SECTIONS AND THEIR MAIN RESEARCH AREAS

G0 SECTION

Major research areas:

Peritoneal inflammation and metabolism during the postoperative period in necrotizing

enterocolitis and congenital abdominal wall defects.

Follow-up and surgical treatment of patients with congenital anomalies with focus on Oesophageal

atresia (surgical methods, pulmonary and oesophageal function).

Anal atresia (surgical reconstruction and bowel function).

Hirschsprung’s disease (functional outcome, intestinal proteomics).

Congenital diaphragmatic hernia (pathophysiology, cardiac, pulmonary and gastrointestinal function).

Abdominal wall defects (general physical function).

Regenerative medicine and experimental surgery with focus with focus on:

Short bowel syndrome.

Long gap esophageal atresia repair.

Bowel wall defects.

Inflammatory bowel disease, surgical treatment, epidemiology, and diagnosis.

Juvenile polyps and polypose syndroms.

G1 SECTION

Focus is on the diagnosis and treatment of pre-maligant and malignant tumors of the upper gastrointestinal

tract (i.e. oesophagus, GEJ, stomach, duodenum, pancreas, bile duct and liver). Clinical research areas

include screening, epidemiology, advanced endoscopy, ultrasound, peri-operative chemo-radiotherapy,

surgery, and follow up. Projects on translational and personalized medicine are included in the pancreas and

gastro-oesophageal cancer research.

Major research areas:

Minimally invasive diagnosis, staging, treatment and follow up of upper gastrointestinal tract cancer.

(Collaborators: Professor George B. Hanna, Academic Surgical Unit, St. Mary’s Hospital, London,

UK, and Professor Lars R. Lundell, MD, PhD, Section for upper GI Surgery, Centre for Digestive

Diseases, Karolinska University Hospital, Huddinge, Stockholm, Sweden).

Colorectal cancer liver metastases (epidemiology, diagnosis, and treatment response evaluation).

(Collaborators: Professor Lars R. Lundell, MD, PhD, Section for upper GI Surgery, Centre for

Digestive Diseases, Karolinska University Hospital, Huddinge, Stockholm, Sweden).

Peritoneal carcinomatosis treated by PIPAC (Pressurized Intraperitoneal Aerosol Chemotherapy).

(Collaborators: Professor Marc Reymond, Department of Surgical Oncology and Therapy Center for

Peritoneal Cancer (Marien Hospital, Ruhr-University, Bochum, Germany).

Cancer-associated fibroblasts and stellate cells in pancreatic cancer.

(Collaborators: Associated Professor Sönke Detlefsen, Department of Clinical Pathology, Odense

University Hospital, Odense, Denmark).

Intraperitoneal tumor cells, tumor-specific cell-free DNA and circulating tumor cells in upper

gastrointestinal tract cancers (Translational research).

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(Collaborators: Professor Torben A. Kruse, Human Genetics, Department of Clinical Research,

Odense University Hospital, Odense, Denmark, and Associated Professor Sönke Detlefsen,

Department of Clinical Pathology, Odense University Hospital, Odense, Denmark).

G2 SECTION (BENIGN)

Research areas of interest are congenital recto-anal anomalies in adulthood, regenerative medicine and

experimental surgery, inflammatory bowel disease, surgical complications, peritoneal inflammation and

metabolism, complicated anorectal fistula, postoperative pain management, patient involvement in treatment,

navigation and support to cancer patients.

Major research areas:

Pelvic Floor Centre - Diagnosis and treatment of patients with acquired and congenital recto-anal

anomalies. Anal incontinence. Obstetric sphincter tear. Development of new treatment principles.

The center will be affiliated to the Centre for Regenerative Medicine. The center will operate in

collaboration with the Department of Urology, the Department of Obstetrics and Gynecology, and the

Department of Pathology, OUH.

Regenerative medicine and experimental surgery – the department is a key player in the

development of new treatments and possible patents for medical equipment/aids in. Collaboration

with the Institute of Pathology, KBF, Biomedical Laboratory, OUH, the Region of Zealand and

industry.

Inflammatory bowel disease - Highly specialized center for the surgical treatment of complications

involved in inflammatory bowel disease. Development of experimental models for pathophysiological

studies. Epidemiological studies. Development of new diagnostic methods including stem cells

therapy. Collaboration with the Department of Nuclear Medicine, Department of Medical Gastro-

Intestinal Diseases and Department of Clinical Epidemiology, OUH.

Surgery Complications – Including center for peritoneal inflammation and metabolism. Development

of new diagnostics for early detection of postoperative complications and the development of new

surgical techniques for the management of post-operative complications. Collaboration with the

Department of Anesthesiology, OUH, surgical departments in the Region of Southern Denmark and

the Region of Zealand and research groups in the Netherlands, Norway and Sweden.

Anorectal surgery – Highly specialized treatment of complicated anorectal fistula.

Patient involvement – The department will be highly specialized within the field of the involvement of

emergency patients. Development of methods for patient involvement, to include pain management

and patient care in acute abdominal pain (PiSAM project). Collaboration with research groups in the

field of patient involvement in England.

Nurse navigation and support to cancer patients

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G2 SECTION (MALIGNANT)

Major research areas:

Neoplastic conditions of the colon and rectum. Focus on large adenomas and early colorectal

cancers including minimally invasive treatment, diagnosis and staging, especially trans-anal

ultrasound techniques, dual energy CT and visualization-fusion techniques EMR, ESD and TEM

surgery.

Screening and camera capsule studies. Camera capsule technology in colorectal cancer screening

in collaboration with dedicated European Screening Centres. The capsule technology in diagnostics

and follow up will also be part of this work package.

Primary, secondary and tertiary prophylaxis against colorectal neoplasia: Prophylactic effect of

Falcarinol and Falcaridiol from carrots to prevent colon neoplasms. Cell lines and rat-based trials are

being conducted, and human studies are planned. Collaboration with The Danish Cancer Society

and the Institute of Chemistry-, Bio- and Enviromental Technology on the molecular mechanisms in

the polyp-inhibitory effects of carrot derived inhibitors will be expanded.

The effect of up-skilled help through the treatment trajectory on colon cancer patients' mental health.

A feasibility study is underway and a randomized multicenter study is planned.

RESEARCH RELATED PROCEDURES & TECHNIQUES

G0 SECTION

Intraperitoneal microdialysis

Gene analysis

Proteomics

Advanced anorectal manometry

Animal experimental studies

Tension-stretch analyses on tissues

G1 SECTION

Endoscopic ultrasound (EUS) guided diagnosis and intervention

Endoscopic RF Ablation (esophagus, stomach, duodenum)

Laparoscopic Ultrasound (LUS) guided dissection and biopsy

LUS guided fiducial marking

Endoscopic mucosa resection

Endoscopic submucosal dissection

Minimal Invasive Oesophagectomy

Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC)

Transgastric necrosectomy

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G2 SECTION

Advanced anorectal manometry

Microdialysis

Scintigraphy

Ultrasound and Ultrasonic derived methods such as elastography

Imaging fusion techniques

Dual Energy Computer Tomography

Transanal endoscopic microsurgery

Endoscopic mucosa resection

Endoscopic submucosal dissection

Full Thickness resection device for flexible endoscopy (FTRD)

SCIENTIFIC PUBLICATIONS (PEER REVIEWED)

G0 SECTION

Jensen R, Ellebæk M, Rasmussen L, Qvist N. Low success rate of salvage surgery for testicular

torsion in newborns. Dan Med J. 2015 Jan;62(1):A4997.

Jelsig AM, Qvist N, Brusgaard K, Ousager LB. Research participants in NGS studies want to

know about incidental findings. Eur J Hum Genet. 2015 Oct;23(10):1423-6.

Hansen LF, Jakobsen C, Pærregaard A, Qvist N, Wever V. Surgery and postoperative recurrence

in Children with Crohn´s disease – a retrospective study (1978-2007). J Pediatr Gastroenterol Nutr.

2015 Mar;60(3):347-51.

Risby, K, Ellebæk MB, Jakobsen MS, Husby S, Qvist N. Intraperitoneal microdialysis in the

postoperative surveillance of infants undergoing surgery for congenital abdominal wall defect. A pilot

study. J Pediatr Surg. 2015 Oct;50(10):1676-80.

Diemer P, Markøw S, Le DQ, Qvist N. Poly-e-caprolactone mesh as a scaffold for in vivo tissue

engineering in rabbit oesophagus. Dis Esophagus. 2015 Apr;28(3):240-5.

Aunsholt L, Thymann T, Qvist N, Sigalet D, Husby S, Sangild PT. Prematurity reduces functional

adaptation to intestinal resection in piglets. JPEN J Parenter Enteral Nutr. 2015 Aug;39(6):668-76.

Jelsig AM, Tørring PM, Kjeldsen AD, Qvist N, Bojesen A, Jensen UB, Andersen MK, Gerdes

AM, Brusgaard K, Ousager LB. JP-HHT phenotype in Danish patients with SMAD4 mutations. Clin

Genet. 2015 Nov 17.

Tøttrup A, Nørgaård BM, Qvist N. Surgery rates in IBD. Gut. 2015;64:187-8 .

Qvist N, Nybo M, The electronic health record is important in monitoring prophylactic drug side

effects. Danish Medical Journal, 2015;177.

Borre M, Qvist N, Raahave D, Worsøe J, Ærthøj JP, Christensen P, Krogh K. Clinical

constipation and importance of lifestyle factors. Danish Medical Journal, 2015;177.

Strebel K, Nielsen SRH, Biagini M, Qvist N. Effect of Humira® on intestinal anastomotic Response

in Rabbits. J Invest Surg. 2015 Jun;28(3):167-72.

Schultz H, Qvist N, Pedersen BD, Mogensen CB. Time delay to surgery for appendicitis. No

differences between surgical assessment unit and emergency unit. Eur J Emerg Med. 2015 Oct 16.

Tind S, Qvist N. Acute appendicitis. The influence of CRP and leucocytes on the descision-making.

Dan Med J 2015;62:A5267.

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G1 SECTION

Nielsen, Michael Friberg Bruun; Mortensen, Michael Bau; Detlefsen, Sönke. Desmoplasiens

and pancreatic stellate cells importance in pancreatic cancer. Danish Medical Journal, Vol. 177, Nr.

34, 17.08.2015, s. 2-5.

Gerleman, Roxana; Mortensen, Michael Bau; Detlefsen, Sönke. Desmoid Tumor of the

Pancreas: Case Report and Review of a Rare Entity. International Journal of Surgical Pathology,

Vol. 23, Nr. 7, 27.07.2015, s. 579-84.

Thornell A, Angenete E, Bisgaard T, Bock D, Burcharth J, Heath J, Pommergaard

HC, Rosenberg J, Stilling N, Skullman S, Haglind E. Laparoscopic Lavage for Perforated

Diverticulitis With Purulent Peritonitis: A Randomized Trial. Ann Intern Med. 2016 Feb 2;164(3):137-

45.

Buchbjerg T, Fristrup C, Mortensen MB. The incidence and prognosis of true duodenal

carcinomas. Journal of Surg Oncol. 2015 Jun;24(2):110-6.

Al-Najami I, Ainsworth AP. Endoscopic ultrasonography is a valuable diagnostic tool in patients

with incidental findings in the pancreas or bile ducts. Dan Med J. 2015 Mar;62(3).

Busse MJ, Ainsworth AP. Ten years of experience with transgastric necrosectomy for walled-off

necrosis in acute pancreatitis. Dan Med J. 2015 Sep;62(9).

Detlefsen S, Mortensen MB, Pless TK, Cribe AS, de Muckadell OB. Laparoscopic and

Percutaneous Core Needle Biopsy Plays a Central Role for the Diagnosis of Autoimmune

Pancreatitis in a Single-Center Study from Denmark. Pancreas. 2015 Aug;44(6):845-58.

Mortensen MB. Novel imaging strategies for upper gastrointestinal tract cancers. Expert Rev

Gastroenterol Hepatol. 2015 Mar;9(3):295-303.

Stilling NM, Fristrup C, Wettergren A, Ugianskis A, Nygaard J, Holte K, Bardram L, Sall M,

Mortensen MB. Long-term outcome after early repair of iatrogenic bile duct injury : A national

Danish multicentre study. HPB (Oxford). 2015 May;17(5):394-400.

Ellebæk SB, Bjerring OS, Mandi B, Detlefsen S. Perivascular epithelioid cell tumours in the liver.

Ugeskr Laeger. 2015 Feb 23;177(9):V10140527.

Hvas CL, Lauritsen M, Mortensen MB. Basics in Medicine & Surgery, 6th edition. Red.: Schroeder,

Schulze, Hilsted, Gøtzsche. Munksgaard 2015.

Plamboeck, A., & Hovendal, C. (2015). The effect of exogenous GLP-1 on food intake is lost in

male truncally vagotomized subjects with pyloroplasty. American Journal of Physiology:

Gastrointestinal and Liver Physiology, 304(12), G1117-1127.

Laursen, S. B., Jakobsen, M., Nielsen, M. M., Hovendal, C., & Schaffalitzky de Muckadell, O. B.

(2015). Transcatheter arterial embolization is the first-line therapy of choice in peptic ulcer bleeding

not responding to endoscopic therapy. Scandinavian Journal of Gastroenterology, 50(3), 264-271.

G2 SECTION

Jensen JS, Petersen NB, Biagini M, Bollen P, Qvist N. Infliximab treatment reduces tensile

strength in intestinal anastomosis. J Surg Res. 2015 Jan;193(1):145-52 .

Lundby L, Hagen K, Christensen P, Buntzen S, Thorlacius-Ussing O, Andersen J, Krupa M,

Qvist N. Treatment of non-IBD anal fistula. Clinical guidelines. Dan Med J. 2015 May;62(5).

Kjaer MD, Simonsen JA, Hvidsten S, Kjeldsen J, Gerke O, Qvist N. Scintigraphic small intestinal

transit time and defaecography in Paients with J-Pouch. Diagnostics (Basel). 2015 Oct 10;5(4):399-

412.

Borly L, Ellebæk MB, Qvist N. Leakage after surgery for rectum cancer: Inconsistency in reporting

to the Danish Colorectal Cancer Group. Surg Res Pract. 2015 Nov 9

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Waage JE, Bach SP, Pfeffer F, Leh S, Havre RF, Ødegaard S, Baatrup G. Combined endorectal

ultasonograph and strain elastogaphy for the staging of early rectal cancer. Colorectal Dis. 2015

Jan;17(1):50-6.

Waage JE, Leh S, Røsler C, Pfeffer F, Bach SP, Havre RF, Haldorsen IS, Ødegaard S, Baatrup

G. Endorectal ultrasonography, strain elastography and MRI differentiation of rectal adenomas and

adenocarcinomas. Colorectal Dis. 2015 Feb;17(2):124-31.

Thygesen MK, Fuglsang M, Miiller MM. Factors affecting patients' ratings of health care

satisfaction. Danish Medical Journal. Dan Med J 2015;62(10):A5150.

Zachariae R, O'Connor M, Lassesen M, Kjær LB, Olesen M, Thygesen M, Mørcke AM. The self-

efficacy in patient-centeredness questionnaire - a new measure of medical student and physician

confidence in exhibiting patient-centered behaviors. BMC Med Educ. 2015 Sep 15;15:150.

Nonner, J., Waage, J. E. R., Hermsen, P. E. A., Baatrup, G., Doornebosch, P. G., & Graaf, E. J.

R. (2015). Endorectal Ultrasonography of Rectal Tumours. I G. Baastrup (red.), Multidisciplinary

Treatment of Colorectal Cancer: Staging – Treatment – Pathology – Palliation. (s.195-206). Chapter

18.Springer.

POSTERS/ORAL PRESENTATIONS

G0 SECTION

Peterslund P, Qvist N, Hansen TP, Husby S, Detlefsen S. Human NEC cases show increased

mast cell count and decreased T cell count in fetal small bowel specimens. Danish Pathology

Society Annual Meeting, March, 2015.

Peterlund P, Detlefsen S, Qvist N, Hansen TP, Husby S. Human NEC cases show increased

mast cell count and decreased T-cell count in fetal small bowel specimens. Danish Paediatric

Society's Child Days,June 2015 Rebild, Denmark.

Qvist N. Mb. Hirschsprung. Danish Surgical Society Annual Meeting, November 2015.

Qvist N. Anal disorders in children. Danish Surgical Society Annual Meeting, November 2015.

Poulsen K, Qvist N. Loperamide vs. Placebo´s efffect on ileostomy ourput. A clinical randomized

double blinded crossover study. Congress for Medical Student Research, March 2015, Nyborg.

Qvist N. Not all CRC patients should be evaluated at MDT. Colorectal Day, June 2015, Aarhus.

Qvist N. The acute treatment of the broken-down abdomen. Danish Surgical Society Annual

Meeting, November 2015.

G1 SECTION

Friss, JT, Bjerring OS, Hildebrabdt MG, Hess S, Gerke O, Høilund-Carlsen PF. Recurrence

detection in pancreatic cancer: The value of quantitative FDG-PET/CT. EANM, April 2015, Hamburg.

Ellebæk SB, Fristrup CW, Salomon S, Støvring J, Bundgaard L, Mortensen MB. Laparoscopic

ultrasonography value by primary resection of colorectal cancer - a prospective center randomized

multicenter study. Danish Surgical Society Annual Meeting, November 2015.

Bjerregaard JK, Ladekarl M, Mortensen MB, Parner VK, Pfeiffer P. FOLFIRINOX in LAPCD,

ESMO 2015.

Joergensen MT, Gerdes AM, Sorensen J, Schaffalitzky de MO, Mortensen MB. Is screening for

pancreatic cancer in high-risk groups cost-effective? Experience from a Danish national screening

program. UEGW, September 2015.

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Joergensen MT, Gerdes AM, Sorensen J, Schaffalitzky de MO, Mortensen MB. Is screening for

pancreatic cancer in high-risk groups cost-effective? Experience from a Danish national screening

program. DSGH Annual Meeting, September, 2015, Hindsgavl.

Drewes A, Mortensen MB. Chronic pancreatitis: Medication or surgery? DSGH Annual Meeting,

September, 2015, Hindsgavl.

Mortensen MB. What is new with PIPAC? (Short Presentations), 2nd International Symposium on

Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC), Marien Hospital Herne, Ruhr-

Universität Bochum, October 2015.

Mortensen MB. Meeting Summary. ØGC Annual Meeting, November 2015, Copenhagen.

Busse MJ, Ainsworth AP. Ten years of experience with open transgastric necrosectomy for

organized pancreatic necrosis in acute pancreatitis. 11th E-AHPBA Congress, April 2015,

Manchester.

Bjerring OS. Re-resection for cancer pancreatis. Pancreasgroup, March 2015, Copenhagen.

Mortensen MB. EUS training in Denmark. EDUCARE, December 2015, Copenhagen.

Ainsworth AP. Treatment of malignant gastric outlet obstruction. What says the literature? Danish

Surgical Society Annual Meeting, November 2015.

Ainsworth AP. Ten years of experience with open transgastric necrosectomy for organized

pancreatic necrosis in acute pancreatitis. Pancreasgroup, March 2015, Copenhagen.

Gerleman, R., Mortensen, M. B., & Detlefsen, S. (2015). Sporadic desmoid tumor of the pancreas.

Abstract from Annual Meeting of the Danish Pathology Society (DPAS), Nyborg.

Friis, J. T., Bjerring, O. S., Hildebrandt, M., Hess, S., & Høilund-Carlsen, P. F. (2015).

Recurrence Detection in Pancreatic Cancer: The Value of Quantitative FDG-PET/CT. Poster session

presented at Congress for Medical Student Research, Nyborg.

Rasmussen, S. B., Mahdi, B., Bjerring, O. S., & Detlefsen, S. (2015). Perivascular epitheloid cell

tumor (PEComa) of the liver – a case report. Abstract from Annual Meeting of the Danish Pathology

Society (DPAS), Nyborg.

Christensen, L., Christesen, H. B. T., Brusgaard, K., Petersen, H., Rasmussen, L., Hovendal,

C., & Detlefsen, S. (2015). Histological features of the pancreas in a patient with congenital

hyperinsulinism due to Beckwith-Wiedemann syndrome. Abstract from Annual Meeting of the Danish

Pathology Society (DPAS), Nyborg.

G2 SECTION

Kjeldsen J, Nielsen J, Larsen MF, Qvist N, Nørgård BM. Postoperative use of anti-TNF-a agents

in patients with Crohn´s disease and risk of reoperation. A nationvide cohort study. ECCO congress,

February 2015, Barcelona.

Qvis N. Dysmotility of the GI tract. Surgical treatment. Danish Sociaty for Gastroenterologi og

Hepatologi, March 2015, Copenhagen.

Qvist N. Stem-cells in surgery. Challenges in research and clinic. Stem Cell Symposium, December,

2015, University of Southern Denmark.

Zachariae R, O 'connor M, Lassesen B, Olesen M, Kjaer LB, Thygesen M, Mørcke AM. Erratum:

The self-efficacy in patient-centeredness questionnaire - A new measure of medical student and

physician confidence in exhibiting patient-centered behaviors, October 2015, BMC Medical

Education(2015)15(170)10.1186/s12909-015-0427-x).

Al-Najami I, Rancinger CP, Buijs M. Baatrup G. Dual energy computed tomography - A novel

image technique to discriminate benign from malignant lymph nodes in rectal cancer specimens.

Poster session presented at European Colorectal Congress, St. Gallen, Switzerland.

Zachariae R, O'Connor M, Lassesen M, Kjær LB, Olesen M, Thygesen M, Mørcke AM. SEPCQ-

27-English Dataset. September 2015. Available at:

https://www.researchgate.net/publication/282003848_SEPCQ-27-English.

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Zachariae R, O'Connor M, Lassesen M, Kjær LB, Olesen M, Thygesen M, Mørcke AM. SEPCQ-

27- Danish Dataset. September 2015. Available at:

https://www.researchgate.net/publication/282003792_SEPCQ-27-Danish.

Schultz, H., & Qvist, N, Patient involvement in pain management at acute abdominal pain. Poster

session presented at 9th Congress of the European Pain Federation (EFIC), 2015, Vienna.

Baatrup, G, 3rd ESO-ESSO Masterclass (invited speaker), March 7 – 12th 2015.

Baatrup, G, "When the end is good ....." (invited speaker),Research day, April 2015, Odense

University Hospital.

Baatrup, G, How do we select patients for transanal excision? (invited speaker), Nordic Earlye

Rectal Cancer Meeting, May, 2015, Bergen.

Baatrup, G, Homedelivered Capsule Endoscopy (invited speaker), European Telemedicine

Conference, October 2015, Odense.

Riishede, M., Focused ultrasonography - does it increase the amount of correct presumptive

diagnoses in the Emergency Department?: A study protocol. Poster session presented at

International Student Research Forum, Aberdeen, 2015.

G3 SECTION

Jensen JS, Antonsen HK, Durup J., Are there advantages of robotic assisted anti-reflux surgery?

Danish Surgical Society Annual Meeting, November 2015.

17 af 17

OUH

Odense Universitetshospital

Svendborg Sygehus

Kirurgisk Afdeling A