annual report · 2017-04-03 · engaging with australia’s eresearch and informatics community,...

Annual ReportCMCA | 2014–2015

Centre for Microscopy,Characterisation and Analysis

01From the Director

02 Affliations

04Techniques

06Feature Story

07Research Highlights

13Impacting on Industry

Cover Image: Tight junction degradation of asthmatic airway epithelium in response to Human Rhinovirus exposure, acquired on the Nikon A1 confocal by Alysia Buckley, CMCA@Perkins

Inside Cover Image: Growing protein crystals, acquired by Paul Rigby on an Olympus BH-2 microscope, captured using polarised light

14User Profile

16Centre Highlights

23Conferences and Visits

26Grant Success

29Journal Papers

50Journal Covers

Multi-modal imaging is just one example of advanced data challenges that CMCA is seeking to meet head on with new academic lead, Dr Andrew Mehnert, who is designing strategies to support users at all levels, and engaging with Australia’s eResearch and informatics community, both within the National Imaging Facility (NIF), the Australian Microscopy and Microanalysis Research Facility (AMMRF), and without. Undoubtedly, more resources are needed in this area, and we are looking for ways to achieve this. But as Andrew’s strategy gains traction, look out for changes to the way you store, access and process your data in the future.

2015 has also seen changes in how we are organised and conduct our business, in response to many factors. Late in the year, we signed an agreement with Murdoch University to give Murdoch users of CMCA the same rights and rates as UWA users, with Murdoch central paying the difference in real cost. This landmark represents a watershed in pan-institutional cooperation in science infrastructure in WA, one that we hope to roll out to ECU and Curtin universities in the near future. Another renewed impetus has been in our engagement with industry, which has seen new projects brought on board, for example, with Proctor and Gamble, and a doubling of our income from these activities.

The CMCA User Pathway is the concept-to-publication sequence of activities that drives all aspects of what we do – ideate – register – plan – train – collect – analyse – publish. From brainstorming and sanity checking at the start, to providing blueprints for methods sections and editing papers at the finish, CMCA’s goal is to provide complete research solutions – and increasingly these solutions involve multiple instrument platforms, and doing more with the data.

Correlative multi-modal microscopy and imaging is a rapidly growing area in which we have many local examples. Now that CMCA supports part of the Western Australian node of Metabolomics Australia (MA), and we have completed the installation of the upgraded NMR facilities, the intersection of mass spectrometry and NMR is presenting opportunities to be engaged, with other Western Australian node members, in a global initiative in phenomics. And now that we have completed the installation of the new focussed ion beam and scanning electron microscopy facilities, we are seeing FIB-SEM combined with transmission electron microscopy (TEM) increasingly being used as a geoscience tool. The same is true for NanoSIMS, as the new instrument forming part of the Advanced Resource Characterisation Facility (a key capability of the National Resource Sciences Precinct) is increasingly being used in combination with electron probe microanalysis and TEM. I could go on, but you get the picture.

From the Director

Image: CMCA Director – Professor David Sampson

As we go to press in 2016, the NCRIS roadmapping process is well underway. As a node of three capabilities, AMMRF, MA and NIF, and partner in two more, the Australian National Fabrication Facility and AuScope, CMCA is definitely a ‘true believer’ in the scheme. We are sincerely delighted that the scheme that has brought you CMCA flagships such as NIF’s 9.4T MRI and AMMRF’s Ion Probe Facility, and has delivered such innovations as the globally acclaimed online training tool MyScope, will continue to deliver for Australian Science.

At the first Exchange of Experience Workshop of Global Bioimaging, in which Australia is a partner, held at the European Molecular Biology Laboratory in Heidelberg, Germany, I can tell you first hand that Australia’s leadership in microscopy and imaging research infrastructure has not gone unnoticed. CMCA will be seeking to continue to live up to this reputation by delivering superior capability to the research community in Western Australia.

cmca.uwa.edu.au 1

The CMCA is a focus for microscopy and microanalysis activities across Western Australia and, through strong links and collaborations, has both a national and international reputation.

Established in 1963 as a science infrastructure facility within The University of Western Australia to support research activity, the Centre has a long and distinguished record of collaboration with researchers, industry and government agencies in the provision of research expertise and technology.

The Centre’s world-class facilities, with a replacement cost of $45M, comprise an extensive range of microscopy, microanalysis and imaging instruments across six sites.

Affiliations

Australian Microscopy and Microanalysis Research Facility (AMMRF)–Node

Established under the Commonwealth Government’s National Collaborative Research Infrastructure Strategy (NCRIS), AMMRF is Australia’s peak research facility for the characterisation of materials through advanced microscopy and microanalysis. The AMMRF facilitates access for all Australian researchers to world-class equipment, instrumentation and expertise through a national grid of nodes with varying microscopy capabilities and an array of flagship instrument platforms at the international cutting edge.

The CMCA is the West Australian node of the AMMRF and features the flagship ion probe capabilities, which consist of the NanoSIMS50, IMS1280 and NanoSIMS50L. Each of these instruments is unique to the Southern Hemisphere.

The CMCA also collaborates with the John de Laeter Centre, which enjoys linked laboratory status in the AMMRF, in the management and operation of Western Australia’s ion probes.

National Imaging Facility (NIF)–Node

Established under NCRIS and expanded under the Commonwealth Government’s Education Investment Fund (EIF), the National Imaging Facility provides state-of-the-art imaging capability of animals, plants and materials for the Australian research community.

In 2009, CMCA became the Western Australian node of the facility, the first organisation to host two NCRIS capabilities. The facility features leading edge imaging capabilities for Western Australia including in vivo micro-CT, multispectral imaging, and X-ray microscopy, as well as the flagship 30cmbore 9.4 T MRI located at the QEII Medical Centre.

Advanced Resource Characterisation Facility– National Resource Sciences Precinct (NRSP)–Node

The National Resource Sciences Precinct (NRSP) is a collaboration between CSIRO, Curtin University and the University of Western Australia (UWA) to connect the world’s best researchers with industry and government to tackle some of the most complex challenges facing the resource industry. The then Federal Minister for Industry, the Hon Ian Macfarlane MP, officially launched the National Resource Sciences Precinct on Tuesday 8 April 2014.

CMCA’s role within the NRSP is to host a node of the Advanced Resources Characterisation Facility (ARCF). Funded by CSIRO’s Science and Industry Endowment Fund (SIEF), the ARCF provides state-of-the-art analytical instrumentation for high-end research in the resources industry. CMCA has augmented its world-class Ion Probe Facility with a new NanoSIMS 50L, installed in 2015. Curtin University hosts a LEAP 4000 for atom probe tomography, and CSIRO is developing its Maia mapper XRF detector to operate without the need for synchrotron radiation.

2 The University of Western Australia

AuScope–Partner

AuScope is the national provider of integrated research infrastructure, bringing together the collective potential of Australian earth science researchers. Funded through NCRIS, AuScope provides a national geoscience and geospatial infrastructure system to transform our understanding of the structure and evolution of the Australian continent.

In partnership with the AMMRF, the Government of Western Australia and UWA, AuScope helped establish the world-class ion microprobe facility at CMCA through the acquisition of the CAMECA IMS1280 large-geometry ion probe. The facility is one of the flagship components of the Earth Composition and Evolution program providing access to cutting-edge geochemical analysis techniques.

Western Australian Centre for Microscopy (WACM)– Lead Node

Together The University of Western Australia, Murdoch University, Curtin University, and Edith Cowan University form the Western Australian Centre for Microscopy (WACM). These four publicly funded universities have a very strong and long collaborative history in regard to electron microscopy and related facilities, which is presently defined by the 2010-2015 Memorandum of Understanding (MoU).

This agreement between the partner institutions sees CMCA acting as the hub for microscopy activities in the State, and strong cross institutional support for infrastructure acquisition and management. The basis of the WACM MoU is that major capital infrastructure must be shared to achieve the most cost- efficient utilisation.

Under the terms of the MoU, researchers from all of the partner universities can access the grouped facilities of WACM without discrimination. This agreement has led to another landmark agreement with Murdoch University to cross subsidise its researchers access to CMCA.

Australian National Fabrication Facility (ANFF) - Partner

Established under NCRIS, the Australian National Fabrication Facility (ANFF) provides researchers and industry with access to state-of-the-art fabrication facilities.

The capability provided by ANFF enables users to process hard materials (metals, composites and ceramics) and soft materials (polymers and polymer-biological moieties) and transform these into structures that have application in sensors, medical devices, nanophotonics and nanoelectronics.

The CMCA houses the Panalytical Empyrean powder diffractometer.

International Atomic Energy Agency (IAEA)–Network Laboratory

The University of Western Australia Safeguards Laboratory (UWASL), located at the Centre for Microscopy, Characterisation and Analysis (CMCA) provides analytical services to the International Atomic Energy Agency using the CAMECA IMS1280 ion microprobe. The analyses consist of measuring the uranium isotopic composition of micron-sized environmental particles collected by inspectors from nuclear facilities around the world, to determine levels of uranium enrichment. The primary purpose is to police the nuclear non-proliferation treaty by monitoring states’ nuclear capabilities, and to potentially identify illicit uranium enrichment facilities or weapons development programs.

UWA is the only University to become a member of the Agency’s Network of Analytical Laboratories (NWAL); other members are governmental agencies, such as the US Air Force, the Japanese and French atomic energy agencies, and the European Commission’s Institute for Transuranium Elements. There are currently 9 members from 7 countries, the EU and the UN, performing particle analyses. This important work is endorsed by the Commonwealth Government’s Department of Foreign Affairs and Trade.

cmca.uwa.edu.au 3

Biological Mass Spectrometry yy Electron and

chemical ionisationyy Fast atom

bombardmentyy Metabolomics

Transmission Electron Microscopyyy Analytical spectroscopyyy Diffractionyy Element mappingyy Imagingyy Tomography

X-ray Diffractionyy Charge density

measurement yy Powder X-ray

diffraction yy Small molecule

structure determinationyy Thin film analysis, XRD

phase analysis, rocking curve analysis

Nuclear Magnetic Resonance Spectroscopyyy Multi dimensional

spectra yy Multinuclear spectrayy Solid state spectra

Scanning Electron Microsopyyy Imagingyy Element mappingyy X-ray microanalysis

(WDS & EDS)Cathodoluminescence imaging

yy STEM imagingyy FIB-SEM

Scanning Probe Microscopyyy Confocal Raman

microscopyyy Atomic Force

microscopyyy Nanoindentation

TechniquesThe CMCA provides the capabilities to characterise the continuum from atoms to small animals.


Optical and Confocal Microscopyyy Confocal, multiphoton

and fluoresence microscopy

yy Laser microdissectionyy Live cell imagingyy Automated digital

histology

Cytometryyy Flow cytometryyy Fluorescence

activated cell sorting (FACS)

yy CyTOF (Time of flight mass cytometry)

yy Luminex bead-based assays

yy Beckman Coulter counter Z2 particle/cell counting and sizing

NIF InVivo Bioimaging Facilityyy Flagship 9.4 T MRIyy Multi spectral

fluorescence imaging

yy Bioluminescence imaging

yy X-ray micro CT

Specimen Preparationyy Biological sciencesyy Cryogenic

preparationyy Physical sciences

Data Management, Analysis and Visualisation yy Data analysisyy Image processing

and reconstruction

X-ray Microscopyyy Microscale 3D

imagingyy In vivo live animal

imagingyy Volumetric data

AMMRF Flagship Ion Probe Facilityyy NanoSIMS and

large-geometry SIMS

yy Sub-µm imaging mass spectrometry

yy High-precision isotope ratios

Image: Element map showing Mg distribution around the fine-grained margins of a meteorite that underwent melting during its plummet earthwards. Image acquired on a JEOL 8530F Hyperprobe by Malcolm Roberts (CMCA). Sample from Gretchen Benedix (Curtin University). Width of image is 500 microns.

cmca.uwa.edu.au 5

Feature Story New NanoSIMS Lab at CMCA

CMCA’s latest addition, the CAMECA NanoSIMS 50L, was delivered on 29th July 2015 and installed alongside the existing NanoSIMS 50 in a new purpose-built lab in the basement of the Physics Building.

This new state-of-the-art ion probe is part of the Advanced Resources Characterisation Facility (ARCF), under the umbrella of the National Resource Sciences Precinct (NRSP) – a collaborative joint venture between CSIRO, Curtin University and the University of Western Australia (UWA). The aim of the NRSP is to connect the world’s best researchers with industry and government, to tackle some of the most complex challenges facing the resources industry.

Funded by CSIRO’s Science and Industry Endowment Fund (SIEF), the ARCF provides cutting-edge analytical instrumentation for high-end academic and industrial research. The three partners each host a specific capability that form a continous characterisation workflow from drill core to atom scale. CSIRO are developing an X-ray flourecsence (XRF) system based on its sucessful synchrotron MAIA detector for rapid element mapping of thin-sections at the mm-scale. UWA has added a second NanoSIMS 50L for isotopic and elemental mapping at the um-scale. While Curtin has installed an Atom Probe, to investigate minerals at the nm-scale.

The new NanoSIMS 50L features several improvements over the existing NanoSIMS 50 (installed in 2003), including a larger magnet, 7 detectors, and full motorisation of the slits and appertures. Most significant, however, is the new RF plasma ion source which produces an oxygen primary ion beam with a spot size of about 50nm. CMCA’s instrument (number 39 in the world) is the first to be installed with the fully integrated RF plasma source.

Image: The two instruments in place in the new basement laboratory at CMCAImage: Fitting through the doorway

Image: The ‘package’ being hoisted up from the ground.


Research Highlights

08Biological Sciences

09Biomedical Sciences

10Earth Sciences

11Physical Sciences

Image: Growing protein crystals, acquired by Paul Rigby on an Olympus BH-2 microscope captured using polarised light”

cmca.uwa.edu.au 7

Lignin is the tough structural molecule of wood and lignification is a common part of the resistance puzzle in Brassicas, protecting vascular tissue from invasion. The resistance mechanisms identified in these studies will be highly valuable for targeted breeding programs to develop new disease-resistant cultivars. They will also enable new, more effective strategies to be developed for managing crop diseases in Australia.

M.B. Uloth, P.L. Clode, M.P. You, M.J. Barbetti. Attack modes and defence reactions in pathosystems involving Sclerotinia sclerotiorum, Brassica carinata, B. juncea and B. napus. Annals of Botany 117:79-95, 2016.

The most cost-effective means to control plant pathogens in economically important crops is to develop resistance within the plants. An understanding of how crops become naturally resistant to Australia’s important fungal and viral pathogens is fundamental to improving the management of crop diseases. However, little is actually known about the processes involved. The Plant Pathology Group led by Professor Martin Barbetti at The University of Western Australia, has been working with Associate Professor Peta Clode at CMCA to define key host resistances of Brassicas to important pathogens. Important Brassica crops include canola, mustard, cabbages, cauliflower and broccoli.

Through a Linkage Project with the Department of Agriculture and Food Western Australia, the team used optical, fluorescence, and scanning electron microscopy in the CMCA to show that the pathogen, Sclerotinia sclerotiorum invades the vascular system of highly susceptible types of Brassica causing rapid rotting of the stems. However, in contrast, resistant Brassicas restrict growth of the fungus by impeding its progress towards stem vascular tissues. They do this by producing more cell layers in the outer part of the stem and rapid lignification of the surrounding tissue. This initiates the rapid death of cells around the infected area.

Biological SciencesStopping stem rot

Image 1: Reactions by Brassica genotypes of varying susceptibility to infection by Sclerotinia sclerotiorum in a field trial. (A) Extreme resistance reaction at 21 dpi (arrowhead). (B) Stem inoculated with an S. sclerotiorum-infested agar plug, attached to the stem with Parafilm, showing sub-surface brown discoloration (arrowheads) caused by S. sclerotiorum infection running longitudinally along the stem from the point of inoculation at 21 dpi. (C) Moderately resistant reaction, showing zonate lesion at 21 dpi. (D) Highly susceptible reaction in B. carinata SMP3-82 at 21 dpi.

Image 2: Light and scanning electron micrographs showing disease progression caused by Sclerotinia sclerotiorum MBRS-1 (A–C) and WW-3 (D) on the stems of Brassica carinata following inoculation using colonized filter paper discs. (A) Extension of S. sclerotiorum along the surface of the stem of susceptible B. carinata SMP3-82 (arrowhead) at 24 hpi. (B) Established hyphal net on the surface of resistant B. carinata 054113 showing infection cushions (arrowhead) at 48 hpi. (C) Subcuticular hyphae visible in susceptible B. carinata SMP3-82 (black arrowhead) and surface hyphae (stained blue, white arrowhead) at 48 hpi. (D) Hyphae in the lesion and on the stem surface became highly vacuolated (arrowhead) by 72 hpi (susceptible B. carinata SMP3-82). Scale bars (B) = 500 µm, (C) = 66 µm, (D) = 10 µm.


Biomedical SciencesA phase 1b clinical trial of the CD40-activating antibody CP-870,893 in combination with cisplatin and pemetrexed in malignant pleural mesothelioma

Malignant pleural mesothelioma is an aggressive cancer usually caused by inhaling asbestos. Although banned in most developed countries, asbestos is still of high economic importance and commonly used in some developing nations. Even in Australia, inadvertent exposure to small numbers of people continues both at home and in the workplace. The long latency period between asbestos exposure and cancer diagnosis means that new cases of mesothelioma will continue to be presented in the clinic for the foreseeable future. Current prognosis is very poor, with median survival around 12 months from diagnosis. The current gold standard chemotherapy for mesothelioma, pemetrexed + cisplatin, is only considered to be palliative rather than curative.

At the National Centre for Asbestos Related Diseases (NCARD), we study drugs that modulate the immune system (“immunotherapy”) in an effort to improve treatment for mesothelioma. Tumours develop mutations resulting in avoidance of detection or attack by the body’s immune system, but some immunotherapies allow tumours to be recognised and destroyed. One such immunotherapy is an antibody that binds and activates the CD40 receptor on dendritic cells (DC). Immature DC take up proteins from their surroundings (such as from dead cells, including tumour cells) and display these to other immune cells as short peptides. If CD4 helper T cells recognise these peptides, they can activate the DC through CD40 signalling. The activated DC can then ‘licence’ CD8 killer T cells to destroy any other cell where the same peptide is found. The anti-CD40 antibody removes the necessity for role of the

CD4 helper cell, in theory making it easier for DC to become activated and therefore licencing more CD8 killer T cells, including those recognising tumour-specific peptides.

Our groupNCARD has previously shown in mice that conventional chemotherapy can work well in partnership with anti-CD40 immunotherapy; broadly speaking, chemotherapy kills cancer cells in a way that assists immune recognition of the tumour, and immunotherapy can then keep the immune system activated in the correct manner to finish the job. We recently published the results of a Phase I clinical trial of anti-CD40 combined with pemetrexed + cisplatin in 15 human mesothelioma patients (Nowak et al 2015). Patients received up to six 21-day treatment cycles, with one dose of chemotherapy and one dose of anti-CD40 per cycle. The combination was tolerable, with six patients achieving at least 30 % tumour shrinkage (Figure 1), all but one achieving some tumour shrinkage, and three surviving over 30 months. Blood samples were collected from patients and analysed for changes in immune cell types. This was done using the flow cytometry facilities at CMCA. Specifically, we saw changes in CD40-expressing CD19+ B cells, which indicates that anti-CD40 activity was

still present even when combined with chemotherapy (Figure 2). The results of this study are promising and warrant further study of combined anti-CD40 and chemotherapy to treat malignant pleural mesothelioma.

Figure 1: Waterfall plot showing change in size of target tumours in each of the 15 mesothelioma patients, as measured by CT scan.

Figure 2: Increases in CD27+ memory B cells as a proportion of total CD19+ B cells, as measured by flow cytometry. Left hand panel shows observed data from weekly blood collections from all patients over max 6 cycles of treatment. Right hand panel shows mathematical modelling of the data, taking into account differences between patients.

This work was supported by: Pfizer Oncology Australia; The Cancer Council Western Australia; National Health and Medical Research Council of Australia; and the Insurance Commission of Western Australia.

2

1

cmca.uwa.edu.au 9

Earth SciencesChanging the picture of Earth’s earliest fossils

stacks of plate-like clay minerals arranged into branched and tapered worm-like chains. Carbon was then absorbed onto the edges of these minerals during the circulation of hydrothermal fluids, giving a false impression of carbon-rich cell-like walls. The advanced elemental mapping capabilities of the recently installed FEI Titan TEM was essential to the study, enabling the interior of the filaments to be imaged and chemically characterised at nano-scale resolution.

M. Brasier, J. Antcliffe, M. Saunders, D. Wacey, Changing the picture of Earth’s earliest fossils (3.5-1.9 Ga) with new approaches and new discoveries. Proceedings of the National Academy of Sciences USA 112, 4859-4864, 2015.

David Wacey and Martin Saunders from CMCA were co-authors of a paper published in Proceedings of the National Academy of Sciences USA.

The study resolved a long running evolutionary controversy involving microscopic filamentous objects from the 3.46 billion year old Apex chert in Western Australia. These objects had been claimed to represent the oldest evidence of cellular life on Earth. However, the new study showed that the distribution of carbon in and around these objects, plus their nano-morphology was incompatible with a biological origin. Using high-spatial resolution correlative microscopy the study clearly demonstrates that the ‘Apex chert microfossils’ comprise

Image: ChemiSTEM elemental map showing a cross section through an Apex chert filamentous object. K (blue) represents the clay mineral, Fe (red) represents iron oxide, and C (yellow) is organic material absorbed onto the edges of the plate-like clay grains. Both the overall morphology and distribution of carbon is incompatible with that seen in a true microfossil.


While typical solvent extractants are too “greasy” to form crystals, Dr Keith Barnard (CSIRO, Mineral Resources) and Professor Mark Ogden (Curtin University) have collaborated to tackle this problem by reducing the size of the greasy hydrophobic groups, while retaining the part of the extractant that binds to the metal ion. With this change, the metal complexes formed can be crystallised, and Professor Skelton can analyse them to determine exactly how the extractant is interacting with the metal. The result is a sequence of structures that gives invaluable information about how the extractant interacts with different metal ions. While extending these results to the solution phase has to be done carefully, the combination of “degreased” solvent extractants with the power of x-ray diffraction gives insights into metal extraction that are hard to match.

Crystallizing insights into solvent extraction

Metals are critical resources for the technological needs of the 21st century, and a range of well-established methods are used to extract these vital metals from ores. There is growing pressure to improve extraction methods, as the need for metals grows, and the quality of available ores decreases. A widely used process in metal purification is solvent extraction, where an organic extractant is used to remove specific metals from complicated aqueous mixtures. These organic extractants are designed to pull metal ions into an organic solvent, while being hydrophobic (or greasy) enough to avoid being dissolved into water.

When trying to improve the efficiency and selectivity of solvent extraction processes it is useful to know exactly how the organic extractant is interacting with the metal ions. This information is very difficult to determine in the liquid phase, but is easily achieved if the materials can be formed into crystals, as this allows Assoc. Professor Brian Skelton from the CMCA to use the power of single crystal x-ray diffraction on the materials, precisely determining the relative positions of all of the atoms in the material.

Image: D. D’Alessio, D.M. Lombardo, J.G. Vaughan, B.W. Skelton, K.R. Barnard, M.I. Ogden, Dalton Transactions, 44, 7163-7168, 2015.

Physical Sciences

cmca.uwa.edu.au 11

2014 – 2015 Number of users per technique

Technique

Num

ber o

f use

rs p

er te

chni

que

Category of trainees

Num

ber o

f hou

rs p

er te

chni

que

Num

ber o

f peo

ple

trai

ned

Technique

2014 – 2015 Number of hours per technique

Research Usage and TrainingCMCA 2014 & 2015 – hours per technique

2014 – 2015 Number of people trained

The number of hours used across the facilities remained strong over the 2014–2015 period, with ~59,000 and ~61,500 hours utilised each year, respectively. In particular, the Bioimaging, SEM and Ion Probe platforms usage increased significantly as uptake of these systems continues to grow within the research community. SEM remained the most heavily utilised area, with nearly 17,000 hrs conducted in 2015 across five instrument platforms. Similarly, the number of users remained consistently high across all platforms over the 2014-2015 period, with new instruments in both the Flow and SEM spaces particularly resulting in increased user interest. CMCA continued to contribute strongly to research training with over 700 users trained over the 2014-2015 period. Within this, more than half of those trained were research students.

BioImaging

Cell Sortin

gFlow MS

NMROptic

alSEM

SPMTEM XRD

SIMS

BioImaging

Cell Sortin

gFlow MS

NMR

Optical

SEMSPM XRD

TEMSIM

S0

25

50

75

100

125

150

175

200

225

250

Student UGStudent - PGResearch Sta�Other 0

20

40

60

80

100

120

140

160

180

200

0

2000

4000

6000

8000

10000

12000

14000

16000

18000

20142014

20152015

2014

2015

BioImaging

Cell Sortin

gFlow MS

NMROptic

alSEM

SPMTEM XRD

SIMS

BioImaging

Cell Sortin

gFlow MS

NMR

Optical

SEMSPM XRD

TEMSIM

S0

25

50

75

100

125

150

175

200

225

250


20

40

60

80

100

120

140

160

180

200

0

2000

4000

6000

8000

10000

12000

14000

16000

18000

20142014

20152015

2014

2015

Usage 2014 2015Users 470 459

Hours 59,010 61,502

BioImaging

Cell Sortin

gFlow MS

NMROptic

alSEM

SPMTEM XRD

SIMS

BioImaging

Cell Sortin

gFlow MS

NMR

Optical

SEMSPM XRD

TEMSIM

S0

25

50

75

100

125

150

175

200

225

250


20

40

60

80

100

120

140

160

180

200

0

2000

4000

6000

8000

10000

12000

14000

16000

18000

20142014

20152015

2014

2015


Biomedical and miscellaneous

• Antaria• Bambury Product Development• Canningvale Australia• Department of Fisheries WA • Epichem• Fertility Specialists of WA• Pivet• Proteomics International • RPH – Cell & Tissue Therapies

International

• Procter & Gamble• PV Consulting• International Atomic Energy Agency

(IAEA)

Impacting on Industry

Energy and minerals

• Alcoa World Alumina• CSIRO Earth Science & Resource

Engineering• Department of Mines and Petroleum• Geological Survey of WA• Oilfield Production Technologies• Paladin Resources• Parsons Brinckerhoff Australia• Thundelarra Exploration

Environmental and engineering

• Analytical Reference Laboratories• Botanic Gardens and Parks

Authority• GHD• Glossop Consultancy• Matrix Composites & Engineering• Safety Rescue Technologies

Australia• Site Environmental & Remediation

Services• SLR Consulting Australia• TSW Analytical

“Bambury has been at the forefront of bedding technology since its early stages of operation. Mite-Guard is one of the longest running ranges for the company and is the chosen product for many allergy sufferers and recommended by allergy and asthma specialists. It features a specially developed micron dust filter membrane that is sandwiched between two layers of inert polypropylene fabric allowing barrier protection against allergens whilst remaining breathable for optimal user comfort. Given the nature of the product has inherent health benefits, it was essential we backed up our claims and had full confidence in our product. CMCA at UWA were able to provide us with the highest quality imaging - far superior to what we had seen in the past from other microscopy services in Australia and overseas. Previous laboratory tests proved the product worked by not allowing microscopic particles to pass through the fabric, but with CMCA we were actually able to see the fabric up close at 2000x magnification, proving the fibres of the filter membrane are packed so tightly together that harmful allergens are not able to pass through. CMCA’s open communications, fast turnaround times and professionalism also made our experience dealing with them a real pleasure.”

BAMBURY:

CMCA has a long history of partnering with industry from small scale analysis, instrument hire and training of individuals, to large scale consulting and complex research contracts worth hundreds of thousands of dollars.

Access is tailored to the needs of your organisation or project and we welcome queries on how we can apply our expertise and world class instrumentation to your problem solving initiatives.

During 2014–15, CMCA served the needs of the following industry through industry engagement:

Image: Micron dust filter membrane

cmca.uwa.edu.au 13

User Profile

Image: Three-dimensional visualisation of a portion of the feto-placental arterial vasculature of a pregnant rat; coloured according to vessel diameter. Images courtesy of Andrew Mehnert, CMCA and Caitlin Wyrwoll, School of Anatomy, Physiology and Human Biology, UWA.

15User Profile


capacity to comprehensively analyze of thousands of single cells in parallel, the ability to isolate many individual cells and analyze each separately is critical. For these types of research approaches, scientists in Professor Lister’s lab use a range of the CMCA equipment, including the BD Influx cell sorter to isolate particular labelled cell types from the brain, and the BD Fortessa flow cytometer for cell counting, sorting and biomarker detection. For example, graduate student Rebecca Simmons has used these instruments to isolate highly pure populations of nuclei and glia from brain material in order to map their epigenome, transcriptome, and regulatory regions of the genome. Furthermore, access to cutting edge microscopes are essential for examining cell type specific gene expression and marker proteins. Dr Marina Oliva, a plant biologist from the Lister lab, utilizes the CMCA’s LAF Nikon A1RMP confocal microscope to identify specific labelled cell types in plant stem cell niches in roots and shoots, allowing subsequent isolation and epigenomic analysis of the individual cell types to provide new insights into the regulation of these cells that are essential for plant growth.

“The advanced facilities available in the CMCA are an essential component of the research programs of many WA scientists, including my own.” says Professor Lister. “My group’s research benefits greatly from the high quality facilities and the expertise of the CMCA staff, who provide dedicated and highly skilled input and assistance for our projects”.

the genome that plays crucial roles in regulating the information contained in the underlying DNA sequence. Each of the myriad different types of cells within an organism turns on or off a distinct combination of genes, and the epigenome plays crucial roles in this process of cellular identity by controlling whether a gene is active or not. Consequently, each different type of cell will display unique epigenome patterns, which can also change through normal development or in disease states.

Professor Lister’s research has yielded new insights into the composition and function of the epigenome in a variety of systems, including plants, the brain, and stem cells. His laboratory is focused upon understanding how these complex epigenome patterns are established and altered, how they affect the readout of underlying genetic information, their role in brain development and function, and developing new molecular tools to precisely edit the epigenome. Much of this research requires that complex tissues from an organism are separated into groups of the same cell type prior to applying DNA sequencing technologies to map the epigenome patterns and gene expression in that cell type. Furthermore, as the field of genome biology is rapidly gaining the

Professor Ryan Lister

Research that aims to understand living organisms at the cellular and molecular level is strongly driven by advanced technologies that enable the manipulation and observation of cells and biomolecules. Recent years have seen extremely rapid advances in technologies that enable deep characterization of cellular information, including the development of next generation DNA sequencing instruments that have made it ~10,000 times cheaper to sequence a genome compared to a decade ago. As massively parallelized DNA sequencing becomes a standard research tool in the biological sciences, it is increasingly important to have access to sophisticated equipment for cell isolation and manipulation, in order to effectively isolate rare or specific cell types for subsequent genomic analyses. Such tools available in the CMCA have become an important component of the epigenetics and genomics research performed in the laboratories of Professor Ryan Lister in the ARC Centre of Excellence in Plant Energy Biology and the Harry Perkins Institute of Medical Research.

Professor Lister leads a research group exploring the epigenome, the molecular code superimposed upon

User Profile

cmca.uwa.edu.au 15

Centre Highlights

Image: Growing protein crystals, acquired by Paul Rigby on an Olympus BH-2 microscope captured using polarised light”

17Centre News

21Staff News

20CMCA HDR Student News


Centre NewsChief Scientist launches CMCA@Perkins and the NIF Flagship MRI at Harry Perkins Institute

Australia’s Chief Scientist Professor Ian Chubb officially opened new NIF Flagship MRI imaging labs in the Harry Perkins Institute of Medical Research on 24 June 2015. These labs include the AMMRF at UWA bioimaging facility, which integrates instruments and expertise in cytometry, microscopy and imaging. The facility mainly serves the research needs of biomedicine and the biosciences, but is available to all scientists and researchers in Western Australia and beyond. The labs also house the National Imaging Facility’s flagship pre-clinical high-field magnetic resonance imaging scanner and other NIF platforms for macro scale imaging. It is the centre piece of CMCA’s growing bioimaging facility that includes live animal fluorescence and luminescence imaging and live animal X-ray microtomography imaging. The proximity of different and complementary characterisation techniques is already facilitating the uptake of new forms of microscopy by researchers to address a range of research challenges.

Over 60 invited guests attended the launch, along with 60 PhD students from the EMBL Australia workshops. Guests included AMMRF Chief Executive Officer Dr Miles Apperley, from the National Imaging Facility, Director of Operations Professor Graham Galloway, and the Chancellor of the University of Western Australia, Dr Michael Chaney AO.

CMCA Research Open Day

During the university’s Research Week in September 2015, CMCA held a Research Open Day over its three facilities at Physics, Perkins and Bayliss where our staff gave talks and conducted site tours of our laboratories and instruments. An exhibition of the AMMRF Incredible Inner Space images was a popular attraction in the Bayliss Building. This showcased a wide selection of images from AMMRF nodes around Australia accompanied by a crystal display exhibit.

Sulphur Rock

ABC news articleA camera crew from ABC News was at CMCA in September 2015, interviewing colleagues from CET about their research on sulphur-bearing rock samples collected in the field and analysed at CMCA. Researchers Stefano Caruso and Dr Crystal LaFlamme use the AMMRF Flagship ion probe facility at CMCA to investigate the role of sulphur in the formation of ore deposits. Rock fragments are prepared as special mounts and the sulphur isotope composition of tiny mineral grains are analysed using CMCAs $6 million CAMECA IMS 1280 ion probe.

Mr Caruso, who is completing the research for his PhD, said the IMS1280 ion probe — the only one in Australia and one of 32 in the world — was essential to the research. The data generated by the ion probe is critical to creating a road map of ore bodies in the region, in turn helping explorers find new deposits.

Image: Mr Stefano Caruso working on the IMS1280 at CMCA

Installation of new FEI Helios focused ion beam (FIB) scanning electron microscopy

The CMCA’s new FIB-SEM facility, funded through an ARC LIEF grant with support from Curtin, Murdoch, ECU, Sydney University, and the CSIRO was successfully commissioned in October 2015. The FEI Helios Nanolab G3 CX DualBeam system is the latest generation of FEI’s world-leading FIB-SEM instruments. The new facility will provide researchers in the physical, biological and geosciences with nanoscale 3D imaging, advanced sample preparation, and nano fabrication capabilities that will complement the existing world-class electron, x-ray and ion beam facilities housed in the CMCA.

cmca.uwa.edu.au 17

Image: X-Ray map of Al distribution in a chondritic meteorite acquired by M Roberts on a JEOL 8530F Hyperprobe. Sample from G Benedix (Curtin University).

Image: X-ray map of AI distribution in a chondritic meteorite acquired by M. Roberts on a Jeol 8530F hyperprobe. Sample from G. Benedix (Curtin University)

Image: Elemental map showing As distribution in a pyrite grain. Image acquired on a JEOL 8530F Hyperprobe by Malcom Roberts (CMCA). Sample from Breno de Souza Martins (CET). Image width 1.5 mm.

CMCA Scientific Advisory Committee

CMCA has established a Scientific Advisory Committee, comprising representatives from the wider research community. The committee’s main role is to advise on strategic directions in science infrastructure provision by CMCA and make recommendations to the CMCA Board on acquisition of new equipment, retention of current equipment and associated support staff, for the benefit of the University and the state of Western Australia.

Open for Business

The University’s Office of Research Enterprise used an image of an Antartic ‘hair grass’ root acquired by Assoc. Professor Peta Clode (CMCA) on a promotional postcard ‘Partner with us for your R&D needs’. The postcard, aimed at attracting research partners to UWA, was used at the Agriculture Biotechnology International Conference in Melbourne and for Research Week at UWA.

Raising funds for Wheelchair Sports WA

CMCA Director Professor David Sampson experienced first hand the difficulties faced by people with a physical disability. On 15th December he spent a day in a wheelchair to raise awareness of people with a disability and raise funds for Wheelchair Sports WA. David did a sterling job and raised over $5,000 through sponsorship.

Journal Boards

Dr David Wacey has been invited to join the Board of two journals: Geobiology from December 2014 and Nature Scientific Reports from May 2015.

The Conversation

A 3.5-billion year old Pilbara find is not the oldest fossil: so what is it? Dave Wacey and Martin Saunders had an article published in The Conversation in 2015: www.theconversation.com/a-3-5-billion-year-old-pilbara-find-is-not-the-oldest-fossil-so-what-is-it-40482.

Image: David Sampson (in wheelchair) with Jeremy Shaw, Malc Roberts and Steve Barnes (CSRIO)


CMCA Occupational Health & Safety

Responsibility for implementation of Health and Safety policy in a core facility such as the CMCA is an obligation that needs to be taken very seriously. In 2014 the CMCA Health and Safety Committee was established to facilitate closer senior management engagement and participation in CMCA Health and Safety matters. This committee meets 3-4 times a year and by involving senior Centre management has the authority to action Health and Safety activities without additional consultation and to discuss and resolve any Health and Safety compliance issues. In its inaugural year a comprehensive review of all Health and Safety documentation was initiated leading to the publication of revised UWA compliant CMCA Health and Safety manuals and supplementary manuals providing local information for our different sites. In addition new risk assessments and standard operating procedures are being produced for all Centre equipment for the benefit of all our staff and users. In turn CMCA staff attend Health and Safety Committees of the Science Faculty and Harry Perkins Institute in order to communicate and discuss Health and Safety matters in a wider context. There is no doubt the Health and Safety Committee has proven to be an effective forum and has helped drive a significant improvement in overall compliance and safety culture at the CMCA.

Dr Peter King, Technical Operations Manager and CMCA Health and Safety Officer.

UWA News articles:

April 2015–Oldest fossils controversy resolvedNew analysis of world-famous 3.46 billion-year-old rocks by researchers from The University of Western Australia is set to finally resolve a long-running evolutionary controversy.

The new research, published this week in Proceedings of the National Academy of Sciences USA, shows that structures once thought to be Earth’s oldest microfossils do not compare with younger fossil candidates but have, instead, the character of peculiarly shaped minerals.

UWA researchers Dr David Wacey and Professor Martin Saunders used transmission electron microscopy to examine ultrathin slices of ‘microfossil’ candidates, to build up nanoscale maps of their size, shape, mineral chemistry and distribution of carbon.

November 2015–Microscope in a NeedleA team of biomedical engineers and doctors, led by CMCA Director Professor David Sampson and Associate Professor Robert McLaughlin, won The Australian newspaper’s Innovation Challenge for developing the world’s smallest handheld microscope.

The team took out first prize and $30,000, competing against a record field of 310 entries from innovators across the country in the national awards which aim to drive some of Australia’s best ideas to commercialisation and honour excellence across a broad range of areas.

Image: Elemental map showing Fe distribution in a spinel grain undergoing leaching through surficial processes in a tropical environment. Image acquired on a JEOL 8530F Hyperprobe by Malcom Roberts. Sample from Martin Wells (CSIRO). Image width 190 microns.

Image: False-coloured back-scattered electron image of a garnet crystal in a metapelitic rock. Image acquired on the JEOL 8530F Electron Microprobe by Dr Malcolm Roberts using Probe Image® Software. Sample courtesy of Dr Sandra Romano (GSWA). Width of image 1mm.

Image: X-ray map showing Ca distribution in a garnet crystal in a metapelitic rock. Image acquired on the JEOL 8530F Electron Microprobe by Dr Malcolm Roberts using Probe Image® Software. Sample courtesy of Dr Sandra Romano (GSWA). Width of image 1mm.

cmca.uwa.edu.au 19

CMCA HDR Student newsAustralian Coral Reef Society Meeting

Congratulations to PhD student Taryn Foster who won the Vicki Harriott Award at the Australian Coral Reef Society Meeting for her work utilising the Versa 520 X-ray CT on coral development. The Meeting was held on Daydream Island, Queensland from 28th–31st July, 2015.

AIMS@JCU student seminar day

One of the primary AIMS@JCU events is the annual AIMS@JCU student seminar day. Each year, this is a successful and well attended event for students to show case the cutting edge research being conducted. The event is an important mechanism for students to share research findings with the broader AIMS and JCU scientific communities as well as compete for financial prizes. PhD student Brian Strehlow (based at AIMS Townsville, 50% CMCA) took out the best student talk award for his presentation on ‘Understanding the impacts of dredging on sponges’. The prize is $1500 for science communication and attendance at the next International Coral Reef Society Conference. Brian’s talk included Xradia microCT data looking at sediment uptake in marine sponges. Brian is co-supervised by Assoc. Professor Peta Clode (CMCA).

CMCA Graduated Students

Dr Rahi Varsani: Dynamics of magnetic nanoparticle chain formation and its effects on transverse proton relaxation rates. Supervised by M. Saunders, T. St. Pierre and S. Iyer. Completed 2014.

Dr Noraini Md Jaafar: Biochar as a soil amendment and habitat for micro-organisms. Supervised by L. Abbott, P Clode and D.Murphy. Completed 2014.

Dr Ivan Lozic: Targeted nanotechnology based therapies for oxidative stress following partial injury to the central nervous system. Supervised by L. Fitzgerald, S. Dunlop, M. Kilburn and S. Iyer. Completed 2015.

Alastair Boyd The identification and characterisation of magnetic iron in the honey bee Apis mellifera. Supervised by P. Clode, J. Shaw and M. House. Completed 2015.

CMCA Current Students

Students who are supervised and co- supervised by CMCA staff:

Alaa Munshi: Developing hybrid noble metal nanoparticles for applications in catlysis, sensing and imaging. Supervised by S. Iyer and M. Saunders.

Brian Strehlow: The effects of dredging on sponges (Porifera). Supervised by G. Kendrick, M Renton, P. Clode, A. Duckworth and N. Webster.

Caio Guilherme Pereira: Genetic mechanisms governing the cellular compartmentation of calcium in Proteaceae species. Supervised by H. Lambers, P. Finnegan, P. Clode, P. White, J. Hammond and R. Oliveira.

Crystal Cooper: Identification of an unknown acoel flatworm (Acoela) from Rottnest Island, Western Australia. Supervised by P. Clode, C. Peacock and A. Thompson

Pia Bessell-Browne: Lethal and sub-lethal impacts of dredge related pressures on corals. Supervised by P. Clode, R. Jones, A. Negri and A. Duckworth.

Gerard Ricardo: The impacts of dredging on the early life histories of corals off Western Australia’s coastline. Supervised by A. Negri, R. Jones and P. Clode.

Liza Roger: Response of calcareous pteropods (Euthecosomata) to environmental change. Supervised by A. George and J. Shaw.

Patrick Hayes: Does calcium toxicity explain the absence of most Proteaceae from calcareous habitats? Supervised by H. Lambers and P. Clode.

Taryn Foster: Potential impacts of higher ocean acidity and warmer water temperatures on Abrolhos Island corals. Supervised by M. McCulloch, P. Clode, J. Falter, J. Gilmour and M.van Keulen.

Wenli Ding: Is the distribution of calcium and phosphorus between leaf cell types the key reason why Lupinus species respond differently to soil pH? Supervised by H. Lambers, J. Clements, P. Clode.

Liesel Gentelli: Analysis of silver coins associated with 17th and 18th century shipwrecks off the WA coast. Supervised by A. Suvorova, W. Bloom, A. Paterson, J.D. Hill, J. Green.

Kate Eiloart: Eukaryote preservation in ancient rocks. Supervised by M. Saunders and D. Wacey.

Roland Kerr: The transfection of cancer cells with high efficiency using fluorinated, magnetic, non-viral agents. Supervised by K. Swaminatha Iyer, T. St Pierre, M. Saunders and C. Evans.


wide range of disciplines including chemistry, soil science, botany, biochemistry, pharmacy, marine archaeology, microbiology, engineering and medicine as well as conference presentations and book chapters on NMR spectroscopy. The work, which has involved international, national and local research collaborations, has covered topics as diverse as determining the structure of iron sequestering compounds in soil to the study of artefacts and timbers from shipwrecks.

Lindsay’s connections with the University and CMCA continue as an Honorary Senior Research Fellow. After a short break to renew his interest in golf, he plans to return to continue some unfinished projects.

To mark Lindsay’s retirement, Scott Stewart of the Asian Journal of Organic Chemistry dedicated a paper to him: “The Total Synthesis of Heraclemycin B through b-Ketosulfoxide and Aldehyde Annulation. K.D.Jones, J.E. Rixson, B. W. Skelton, K. M. Gericke, and S.G. Stewart. “This article is dedicated to Dr. Lindsay Byrne on the occasion of his retirement”. Asian Journal of Organic Chemistry, Vol 4 (9) 936-942 September 2015

Promotion

Peta Clode was promoted to Associate Professor in 2015. Peta has been at the CMCA for 15 years and is the Biological Science Application Group Leader. She also held the position of Deputy Director of the CMCA in 2014/2015.

Staff News

Metabolomics Australia

Metabolomics Australia at UWA integrated with CMCA in January 2016. Dr Michael Clarke, Ms Dorothee Hahne, Ms Maike Bollen and Ms Laila Abudulai were welcomed to the CMCA team. There are currently five Metabolomics Australia research nodes around the country housing staff and equipment dedicated to servicing researchers interested in small molecule analysis - amongst which Metabolomics Australia at UWA is one

New Staff

Andrea Holme (2015)Dr Andrea Holme joined the CMCA team in June 2015 and is leading the cytometry facility located at CMCA@Perkins. She has worked in a number of countries in a variety of academic research and commercial GMP/GLP positions as well as pursued her own research interests in cell death and redox signalling in cancer biology, neuroscience and drug development. Andrea looks forward to sharing her experience gained over the years. As a biological researcher, Andrea was drawn to cytometry’s ability to interrogate cellular events in a multi-parameter and quantitative manner, discover new populations and separate these into functional single cells for further analysis using “-omics” platforms.

Retirement

CMCA said farewell to Dr Lindsay Byrne when he retired on 30th June 2015. Lindsay’s association with UWA spans five decades. He joined the UWA staff as manager of the NMR facility in the School of Chemistry in 1976 after completing a BSc with first class honours in 1973 and embarking on a PhD in Organic Chemistry which he completed part time after accepting the NMR position. The following 38 years saw many changes to the NMR facility including the move to the School of Biomedical Biomolecular and Chemical Sciences in 2002 and the subsequent incorporation into the CMCA in 2011. A number of successful RIEF and LIEF grants saw the instrumentation grow from the original 60 and 90 MHz spectrometers to the current range of 300, 400, 500 and 600MHz spectrometers with the latest installation taking place in early 2015.

Lindsay’s research, which is focused in the application of NMR spectroscopy to study the structure and interactions of organic and organometallic molecules, has resulted in publications in a

cmca.uwa.edu.au 21

Gareth Nealon (2016)Gareth Nealon completed his PhD thesis in Chemistry in 2007 at UWA on a series of mesogenic and surface active complexes of the “sarcophagine” class of macrocyclic ligands with Prof. George Koutsantonis and Assoc. Prof. Jack Harrowfield. Postdoctoral Fellowships followed at Curtin University with Prof. Mark Ogden on advanced crystal growth modifiers, and at the IPCMS-CNRS in Strasbourg with Dr. Bertrand Donnio and Prof. Sylvie Bégin-Colin, working on mesomorphic organo-nanoparticle hybrids. Gareth was Project Manager for the SUPERIOR ITN with Prof. Paolo Samorì, and then taught at the European School of Strasbourg before returning to UWA and the CMCA.

Andrea said it’s an exciting time to be part of the field of cytometry. While flow cytometry has traditionally been thought of as an immunologist’s technique, it’s now increasingly being applied to other biological areas. Many imaging and mass spectrometry techniques, probes, and data analysis methods are being adapted and integrated into today’s cytometry, and CMCA houses many of these systems and expertise including the newly acquired CyTOF and the ability to do high content imaging. Andrea looks forward to working with researchers to use and develop these.

Mark Howard (2016)

Dr Mark Howard has worked in the field of NMR spectroscopy for over 25 years with much of this time spent using NMR to study proteins, peptides, drug discovery, bioprocessing and natural products. He has previously worked at Cambridge University and GE HealthCare and University of Kent. Mark is specifically interested in advancing NMR methodologies and he specialises in saturation transfer difference (STD NMR) for ligand binding and drug discovery, natural product analysis and using fluorine NMR in biology. Mark joined CMCA in May 2016 as Senior Lecturer in Nuclear Magnetic Resonance. Mark comes to CMCA from the University of Kent in UK.

Staff List

• Prof. David Sampson (Director)• Assoc/Prof. Peta Clode (Deputy

Director)• Sean Webb (Centre Manager)• Dr Tamara Abel• Liz Albert• Dr Thomas Becker• Alysia Buckley• Dr Lindsay Byrne (Honorary 2015)• Dana Crisan• Dr Aaron Dodd• Peter Duncan• Diana Engineer• Dr Kirk Feindel• Dr Paul Guagliardo• Assoc/Prof. Brendan Griffin

(Honorary)• Jeanette Hatch• Dr Andrea Holme • Dr Heejin Jeon • Dr Haibo Jiang• Prof. Andrew Johnson (Honorary)• Assoc/Prof. Matt Kilburn• Dr Peter King• Lyn Kirilak• Prof. John Kuo (Honorary)• Irma Larma• Assoc/Prof. Matthew Linden (2014)• Dr Laure Martin• Dr Andrew Mehnert• Dr Janet Muhling• John Murphy• Steve Parry • Dr Anthony Reeder• Assoc/Prof. Paul Rigby• Dr Malcolm Roberts• Dr Jeremy Shaw• Assoc/Prof. Martin Saunders• Dr Brian Skelton• Dr Alexandra Suvorova• Dr David Wacey (joint appointment

with UWA School of Earth and Environment)

• Hava Zhang


Conferences and Visits

Image: False coloured ZnO images, acquired by Aaron Dodd

24Visitor Highlights

25Conferences

cmca.uwa.edu.au 23

Visitor Highlights

Image: Matt Kilburn, Anthony Fortini, Tom Yates, Peter King, Lisa Melvin, Sean Webb

March 2015Jeremy Hill, curator of the Iron Age Collections, Prehistory and Early Europe at the British Museum, London paid a visit to CMCA. Centre staff showed off some of CMCA’s capabilities including SEM/EDS, microCT, NanoSIMS and the IMS1280.

May 2015Professor Qingming Luo, VP of HuaZhong University of Science and Technology (HUST), China visited CMCA and was taken on a tour of CMCA@Physics and CMCA@Perkins.

May 2015A group of eight staff from Medical Engineering and Physics Department at Royal Perth Hospital came to CMCA for a SEM-EDS workshop, conducted by Alexandra Suvorova.

June 2015A group of students from Scotch College, in conjunction with Pauline Charman the Community Education Manager in the Lotterywest BioDiscovery Centre, visited CMCA@Perkins and were given a tour of the labs by Dr Paul Rigby.

Image: WA Governor Kerry Sanderson with Assoc. Professor Matt Kilburn and Professor David Sampson

August 2015The Centre was very pleased to host a visit from the WA Governor, Her Excellency Mrs Kerry Sanderson, on Friday 21 August 2015. Professor Robyn Owens, Deputy Vice- Chancellor (Research) and Centre Director Professor David Sampson accompanied the Governor on her visit. Also in attendance were CMCA Deputy Director Assoc. Professor Peta Clode and Centre Manager Mr Sean Webb. Mrs Sanderson was very enthusiastic about the research being carried out at CMCA and said the tour of the Centre’s facilities, demonstration of instruments and discussions with staff allowed her to become more familiar with the excellent research and development being carried out by the committed staff and researchers, both those from the Centre and others who use the amazing instruments. The scope and standard of the research being conducted using the Centre is impressive and the collaboration and cooperation with other research centres and industry outstanding.

Image: Visitors from Royal Perth Hospital attending a SEM EDS workshop

September 2015Two students from Shenton College attended CMCA@ Perkins under the UWA Learning Links programme from, 7–11 September 2015. The students were given the title of Lab Techs and were shown some basic experiments: making pollen grain slides, performing immunofluorescence, making blood smears and staining the blood to be put through the flow cytometers. They were also shown basic imaging techniques and were taken on a tour of CMCA@Physics.

November 2015Mr Tom Yates, the Australian consul general and trade commissioner from Japan, came to Perth and expressed his interest in learning more about UWA and in particular the Research & Development capabilities at the university. Mr Yates was given a short tour of the NanoSIMS labs at CMCA.


Out and about

May 2015Assoc. Professor Matt Kilburn was invited to present at the launch symposium for the ProVIS facility at the Helmholz Centre for Environmental Research (UFZ) in Leipzig.

July 2015International Year of LightProfessor David Sampson headed up the ‘Year of Light Committee’ in Western Australia, which organised various activities around light to raise awareness of how light is used in our daily lives. He was invited to speak at CONASTA, the national science teacher’s conference that was held in Perth in July 2015. The title of his talk was “Light for the Future: The UNESCO International Year of Light”. Professor Sampson was a guest at the CONASTA dinner held at Government House.

Image: Professor David Sampson, Dr Ian MacLeod (WA Museum) and Professor Lyn Beazley (WA Science Ambassador) at the CONASTA dinner held at Government House.

Conferences

September 2015Whilst attending a conference in Bucharest, Professor David Sampson received a special invitation to attend the Elisabeta Palace as a guest, at an evening dedicated to Romanian-born German scientist Professor Stefan Hell who received the Nobel Prize for Chemistry in 2014.

HRH Crown Princess Margaret presented the award to Professor Hell, on behalf of His Majesty King Michael I of Romania Crown Order in rank of Commander.

In the presence of eminent scientists from Europe, America, Asia and Australia, and officials of the Romanian Academy, Crown Princess and Prince Radu gave a dinner in honour of Nobel Laureate.

cmca.uwa.edu.au 25

Grant Success272014

282015

Image: MicroCT image of a bulbous tignid ~2 mm – Courtesy of Dr Nikolai Tatarnic, Western Australian Museum


ARC Linkage, Infrastructure, Equipment & Facilities: David Sampson; Shaun Collin; Martin Hill; Yinong Liu; Martin Saunders; Steve Reddy; Gretchen Benedix; Craig Buckley; Katy Evans; Birger Rasmussen; Lai Chang Zhang; Zongwhen Liu; Ravinder Anand; Stephen Barnes; Andrew Thompson; Gamini Senanayake. Ultra-high resolution focussed ion beam facility for Western Australia. $1,060,000.

ARC Linkage, Infrastructure, Equipment & Facilities: David Sampson; Shaun Collin; Andrew Whiteley; David Mackey; Matthew Linden; Michael Berndt; Philip Newsholme; Giuseppe Verdile; Janina Tirnitz-Parker; Delia Nelson; Simon Mallal; Una Ryan; Phil Stumbles; Garth Maker; Ralph Martins; Mel Ziman; Elin Gray; Deborah Strickland; Jason Waithman; Meegan Howlett; Bree Foley. Mass Cytometry: A breakthrough in multidimensional systems biology. $440,000.

ARC Linkage, Infrastructure, Equipment & Facilities: Harvey Millar; Peta Clode; Gavin Flematti; Peter Leedman; Dongke Zhang; Kliti Grice; Michael Bunce; Richard Oliver; Kar-Chun Tan; Robert Trengove; Garth Maker; Andrew Thompson; Steve Wilton; Ralph Martins; Chriss Abbiss; Dr Mary Boyce. High resolution mass spectrometry for metabolomics and proteomics research. $670,000.

ARC Linkage, Infrastructure, Equipment & Facilities: Paul Low; Thomas Becker; Peta Clode; George Koutsantonis; Killugudi Swaminatha-Iyer; Julian Gale; Amir Karton; Damien Arrigan; Mark Ogden. An STM/AFM Facility for Electroactive Materials Characterisation. $150,916.

ARC Future Fellowship: David Wacey. New insights into the origin and evolution of life on Earth. $767,444.

ARC Discovery Program: Killugudi Swaminatha-Iyer, Pilar Blancafort, Timothy St Pierre, Martin Saunders, Keith Stubbs, Jon Dobson. Magnetofection In An Oscillating Magnetic Field. $484,600.

Neurotrauma Research Program: Sarah Dunlop, Killugudi Swaminatha lyer, Michael House, Kirk Feindel. Using nanotechnology to prevent localised, as well as remote, inflammation and breakdown of the blood brain barrier following neurotrauma. $90,000.

Department of Health (WA): Matthew Linden. Developmental Haemostasis: Platelet function and monocyte-platelet interaction in childhood. $75,000.

Ada Bartholomew Medical Research: Matthew Linden. Developmental haemostasis: Age-specific differences in the blood clotting of children. $28,471.

Four CMCA staff received Travel Grants through the UWA Professional Staff Development Fund that were used to attend conferences and workshops: Malcolm Roberts. Australian Conference on Microscopy and Microanalysis, ACMM23, 2014; John Murphy ($750) Focus on Microscopy 2014; Peter King ($1,500) Laboratory Management Conference 2014; and Irma Larma ($1,500) Australasian Cytometry Society Conference 2014.

CMCA Successful Grants – 2014

cmca.uwa.edu.au 27

UWA Research Awards and Honours 2015

The UWA Research Awards and Honours 2015 recipients were announced at a ceremony during UWA Research Week in September 2015. Professor David Sampson was awarded one of eight Vice-Chancellor’s Senior Research Awards, each person receiving $2,500.

Conference; Mrs Lyn Kirilak ($ 1,532.50) attended a staff development workshop and laboratory visits for electron microscopy technicians; Ms Alysia Buckley ($3,000) attended the Cyto 2015 Conference.

An NHMRC equipment grant was awarded to a team looking at enhancing single cell characterisation. CMCA’s Dr Andrea Holme was first investigator for the team, which included Professor David Sampson, Assoc. Professor Aron Chakera, Assoc. Professor Michaela Lucas, Assoc. Professor Melinda Fitzgerald, Professor Ryan Lister, Professor Swaminatha Iyer, Dr Willem Joost Lesterhuis, Assoc. Professor Matthew Linden, Dr Alison McDonnell, Dr Renne Firman and Dr Kara E. Yopak.

LIEF Outcomes

The team of Professor David Sampson; Prof. Michael Berndt; Prof. Shaun Collin; Dr Elin Gray; Dr Massimiliano Massi; Assoc. Prof. Kevin Pfleger; Dr Jeremie Rossy; Prof. Ian Small; Dr Killugudi Swaminatha-Iyer; Prof. Richard Thompson and Prof. Mel Ziman was successful in obtaining a funding of $850,000 for their project “A Single Molecule Characterisation and Super-Resolution Optical Microscopy Capability in Western Australia”

A project by Dr Peter Munro, an Australian Postdoctoral fellow with the School of Electronic and Computer Engineering and the Centre for Microscopy, Characterisation and Analysis (CMCA), received $772,104 in funding.

Dr David Wacey, of the School of Earth and Environment and the CMCA, received $767,444 for a project which aims to provide new insights into the origin of life on Earth, life’s diversification through the Precambrian, and the co-evolution of life and early Earth environments.

Dr Haibo Jiang was awarded a Research Collaboration Award of $19,664 for his project “Direct Visualization of Lipid Transport by the NanoSIMS”. Dr Jiang will collaborate with colleagues from University of California, Los Angeles and University of Oxford.

An NHMRC Equipment Grant was awarded to Associate Professor Paul Rigby, Professor David Sampson, Dr Nikolajs Zeps, Professor Peter Leedman, Professor Bruce Robinson and Professor George Yeoh, ‘Nikon TiE inverted epifluorescence microscope and components.’—$21,704.

Three CMCA staff were awarded Technical Development Grants that were used to attend conferences and workshops. Dr Malcolm Roberts ($2,300) attended the AMAS Xiii

CMCA Successful Grants – 2015

28 The University of Western Australia cmca.uwa.edu.au 28

Journal Papers302014

392015

Image: A false-coloured back-scattered electron image of a shergottitic meteorite. Image acquired on the FEI Verios SEM by Malcolm Roberts (CMCA). Sample from Gretchen Benedix (Curtin University).

cmca.uwa.edu.au 29

8. K.R. Barnard, D.W. Shiers, M.J. Mc ldowie, B.W. Skelton, M.I. Ogden and T.M. McCoy, Characterization and inhibition of a nickel-alpha-hydroxyoxime (LIX63) salt precipitate formed under proposed commercial operating conditions, Industrial & Engineering Chemistry Research, 53: 8208-8214, 2014

9. P. Bessell-Browne, M. Stat, D. Thomson and P.L. Clode, Coscinaraea marshae corals that have survived prolonged bleaching exhibit signs of increased heterotrophic feeding, Coral Reefs, 33(3): 795-804, 2014

10. S.R. Bird, M. Linden and J.A. Hawley, Acute changes to biomarkers as a consequence of prolonged strenuous running, Annals of Clinical Biochemistry, 51(2): 137-150, 2014

11. B. Bohman, R.D. Phillips, M.H.M. Menz, B.W. Berntsson, G.R. Flematti, R.A. Barrow, K.W. Dixon and R.D. Peakall, Discovery of pyrazines as pollinator sex pheromones and orchid semiochemicals: implications for the evolution of sexual deception, New Phytologist, 203: 939-952, 2014

12. J. Bougoure, M. Ludwig, M. Brundrett, J. Cliff, P. Clode, M. Kilburn and P. Grierson, High-resolution secondary ion mass spectrometry analysis of carbon dynamics in mycorrhizas formed by an obligately myco-heterotrophic orchid, Plant Cell and Environment, 37(5): 1223-1230, 2014

13. R.A. Boulos, F. Zhang, E.S. Tjandra, A.D. Martin, D. Spagnoli and C.L. Raston, Spinning up the polymorphs of calcium carbonate, Scientific Reports, 4: 3616 (1-6), 2014

14. G.A. Bowmaker, J.V. Hanna, S.P. King, F. Marchetti, C. Pettinari, A. Pizzabiocca, B.W. Skelton, A.N. Sobolev, A. Tabacaru and A.H. White, Complexes of copper(I) thiocyanate with monodentate phosphine and pyridine ligands and the P(,N)-donor diphenyl(2-pyridyl)phosphine, European Journal of Inorganic Chemistry, 2014: 6104-6116, 2014

Journal publications

1. J. Abduo, M. Bennamoun, M. Tennant and J. McGeachie, Precision of digital prosthodontic planning for oral rehabilitation, British Journal of Applied Science & Technology, 4(27): 3915-3929, 2014

2. V. Agarwal, E.S. Tjandra, K.S. Iyer, B. Humfrey, M. Fear, F.M. Wood, S. Dunlop and C.L. Raston, Evaluating the effects of nacre on human skin and scar cells in culture, Toxicology Research, 3: 223-227, 2014

3. C.C. Anyaegbu, C. Chidozie, R.A. Lake, K. Heel, B.W. Robinson and S.A. Fisher, Chemotherapy enhances cross-presentation of nuclear tumor antigens, PLoS ONE, 9(9): e107894 (1-8), 2014

4. L. Avadiar, Y-K. Leong, A. Fourie, T. Nugraha and P.L. Clode, Source of Unimin kaolin rheological variation–Ca2+ concentration, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 459: 90-99, 2014

5. L. Avadiar, Y-K. Leong and A. Fourie, Effects of polyethylenimine dosages and molecular weights on flocculation, rheology and consolidation behaviors of kaolin slurries, Powder Technology, 254: 364-372, 2014

6. C.A. Bader, R.D. Brooks, Y.S. Ng, A. Sorvina, M.V. Werrett, P.J. Wright, A.G. Anwer, D.A. Brooks, S. Stagni, S. Muzzioli, M. Silberstein, B.W. Skelton, E.M. Goldys, S.E. Plush, T. Shandala and M. Massi, Modulation of the organelle specificity in Re(I) tetrazolato complexes leads to labeling of lipid droplets, RSC Advances, 4: 16345-16351, 2014

7. C. Balaratnasingam, M.H. Kang, P. Yu, G. Chan, W.H. Morgan,S.J. Cringle and D.Y. Yu, Comparative quantitative study of astrocytes and capillary distribution in optic nerve laminar regions, Experimental Eye Research, 121: 11-22, 2014

2014Book chapters

1. Y. Chew, A.J. Holmes and J.B. Cliff,

Visualization of metabolic properties

of bacterial cells using nanoscale

secondary ion mass spectrometry

(NanoSIMS), In: Environmental

Microscopy, Methods in Molecular

Biology, Volume 1096: 133-146, 2014

2. H. He and Y. Kirilak, Application of SEM

and EDX in studying biomineralization

in plant tissues, In: Electron

Microscopy, Chapter 29: 663-675, 2014

3. M.R. Kilburn and P.L. Clode, Elemental

and Isotopic Imaging of Biological

Samples Using NanoSIMS, In: Electron


4. J. Kuo, Processing Plant Tissues for

Ultrastructural Study, In: Electron


5. M. Saunders and J.A. Shaw, Biological

Applications of Energy-Filtered TEM,

In: Electron Microscopy, Chapter 31:

689-706, 2014

6. D. Wacey, The fossil record of early

life on Earth, In: Astrobiology: An

Evolutionary Approach, 163-198, 2014

7. A. Curatolo, B.F. Kennedy, D.D.

Sampson, T.R. Hilman, Speckle in

optical coherence tomography, In:

Advanced Biophotonics: Tissue

optical sectioning, Chapter 6: 211-277


15. M. Bradshaw, D. Ho, M.W. Fear, F. Gelain, F.M. Wood and K.S. Iyer, Designer self-assembling hydrogel scaffolds can impact skin cell proliferation and migration, Journal of Tissue Engineering and Regenerative Medicine, 4: 6903 (1-6), 2014

16. M.I. Bruce, A. Burgun, M. Jevric, J.C. Morris, B.K. Nicholson, C.R. Parker, N. Scoleri, B.W. Skelton and N.N. Zaitseva, Some cyclic ligands obtained from reactions of polycyanocarbone metal complexes, Journal of Organometallic Chemistry, 756: 68-78, 2014

17. M. Buccini, K.A. Punch, B. Kaskow, G.R. Flematti, B.W. Skelton, L.J. Abraham and M.J. Piggott, Ethynylbenzenoid metabolites of Antrodia camphorata: synthesis and inhibition of TNF expression, Organic & Biomolecular Chemistry, 12: 1100-1113, 2014

18. M. Buccini and M.J. Piggott, A four-step total synthesis of radermachol, Organic Letters, 16: 2490−2493, 2014

19. Burgun, B.G. Ellis, T. Roisnel, B.W. Skelton, M.I. Bruce and C. Lapinte, From molecular wires to molecular resistors: TCNE, a class-III/class-II mixed-valence chemical switch, Organometallics, 33: 4209-4219, 2014

20. E.A. Buvaylo, V.N. Kokozay, O.Yu. Vassilyeva and B.W. Skelton, Bis{2-[(pyridin-2-yl)methylideneamino]-benzoato-k3N,N’,O}chromium(III) nitrate monohydrate, Acta Crystallographica Section E, E70: m136, 2014

21. E.A. Buvaylo, V.N. Kokozay, O.Yu. Vassilyeva and B.W. Skelton, Crystal structure of bis(2-{[(pyridin-2-yl)methylidene]amino}-benzoato-κ3N,N’,O)cobalt(II) N,N-dimethylformamide sesquisolvate, Acta Crystallographica Section E, E70: 164-166, 2014

22. E.A. Buvaylo, V.N. Kokozay, K. Rubini, O.Y. Vassilyeva and B.W. Skelton, Unusual cocrystals made of a Schiff base metal complex and an organic molecule – Close-packing vs. hydrogen bond interactions, Journal of Molecular Structure, 1072: 129-136, 2014

23. S.M. Chai, S. Kavangh, S.S. Ooi, G.F. Sterrett, G. Cull, M. Plunkett, D. Spagnolo, B. Amanuel, D. Joske, C. Leslie, T. Barham and F. Frost, Anaplastic large-cell lymphoma associated with breast implants: A unique entity within the spectrum of peri-implant effusions, Diagnostic Cytopathology, 42(11): 929-938, 2014

24. S. Chakrabarti-Bell, S. Wang and K.H.M. Siddique, Flour quality and disproportionation of bubbles in bread doughs, Food Research International, 64: 589-597, 2014

25. M. Challenor, P. Gong, D. Lorenser, M.J. House, R.C. Woodward, T.G. St. Pierre, M. Fitzgerald, S.A. Dunlop, D.D. Sampson and K.S. Iyer, The influence of NaYF4:Yb,Er size/phase on the multimodality of co-encapsulated magnetic photon-upconverting polymeric nanoparticles, Dalton Transactions, 43(44): 16780-16787, 2014

26. C.S. Chang, M. Kostylev, E. Ivanov, J. Ding, and A.O. Adeyeye, The phase accumulation and antenna near field of microscopic propagating spin wave devices, Applied Physics Letters, 104: 032408, 2014

27. E.J. Chan, S. Grabowsky, J.M. Harrowfield, M.W. Shi, B.W. Skelton, A.N. Sobolev and A.H. White, Hirshfeld surface analysis of crystal packing in aza-aromatic picrate salts, CrystEngComm, 16: 4508-4538, 2014

28. A-L. Chaudhary, D.A. Sheppard, M. Paskevicius, M. Saunders and C.E. Buckley, Mechanochemical synthesis of amorphous silicon nanoparticles, RCS Advances, 4: 21979-21983, 2014

29. A-L. Chaudhary, D.A. Sheppard, M. Paskevicius, C.J. Webb, E.M. Gray and C.E. Buckley, Mg2Si nanoparticle synthesis for high pressure hydrogenation, Journal of Physical Chemistry C, 118(2): 1240-1247, 2014

30. B.C. Cheah, J.M. Dell and A.J. Keating, Tailoring anchor etching profiles during MEMS release using microfluidic sheathed flow, Journal of Microelecromechanical Systems, 23(4): 918-926, 2014

31. X. Chen, N.M. Smith, K. S. Iyer and C.L. Raston, Controlling nanomaterial synthesis, chemical reactions and self assembly in dynamic thin films, Chemical Society Review, 43(5): 1387-1399, 2014

32. X. Chen, K. Vimalanathan, W. Zang, A.D. Slattery, R.A. Boulos, C.T. Gibsona and C.L. Raston, Self-assembled calixarene aligned patterning of noble metal nanoparticles on graphene, Nanoscale, 6: 4517-4520, 2014

33. X. Chen, P.K. Eggers, A.D. Slattery, S.G. Ogden and C.L. Raston, Template-free assembly of three-dimensional networks of graphene hollow spheres at the water/toluene interface, Journal of Colloid and Interface Science, 430: 174-177, 2014

34. Y. Cheng, C. Liu, H.M. Cheng and S.P. Jiang, One-pot synthesis of metal-carbon nanotubes network hybrids as highly efficient catalysts for oxygen evolution reaction of water splitting, ACS Applied Materials & Interfaces, 6(13): 10089-10098, 2014

2014 Journal papers

Total 199Biological Sciences 45Earth Sciences 33Biomedical Sciences 26Physical Sciences 95

cmca.uwa.edu.au 31

35. L. Chin, A., Curatolo, B.F. Kennedy, B.J Doyle, P.R.T. Munro, R.A. McLaughlin and D.D. Sampson, Analysis of image formation in optical coherence elastography using a multiphysics approach, Biomedical Optics Express, 5(9): 2913-2930, 2014

36. L. Chin, B.F. Kennedy, K.M. Kennedy, P. Wijesinghe, G.J. Pinniger, J.R. Terrill, R.A. McLaughlin and D.D. Sampson, Three-dimensional optical coherence microelastography of skeletal muscle tissue, Biomedical Optics Express, 5(9): 3090-3102, 2014

37. S. Chumphongphan, U. Filso, M. Paskevicius, D.A. Sheppard, T.R. Jensen and C.E. Buckley, Nanoconfinement degradation in NaAlH4/CMK-1, International Journal of Hydrogen Energy, 39(21): 11103-11109, 2014

38. E. Clayton, M. Hattie, A.W. Debowski, and K.A. Stubbs, The synthesis of carbohydrate-based natural products from Leonurus japonicus and their biological evaluation as anti-oxidants, Australian Journal of Chemistry, 67: 1461-1470, 2014

39. A.L. Cleaver, K. Bhamidipaty, B. Wylie, T. Connor, C. Robinson, B.W. Robinson, S.E. Mutsaers and R.A. Lake, Long-term exposure of mesothelial cells to SV40 and asbestos leads to malignant transformation and chemotherapy resistance, Carcinogenesis, 35(2): 407-414, 2014

40. D. D’Alessio, A.N. Sobolev, B.W. Skelton, O. Fuller, R.C. Woodward, N.A. Lengkeek, B.H. Fraser, M. Massi and M.I. Ogden, Lanthanoid “bottlebrush” clusters: remarkably elongated metal−oxo core structures with controllable lengths, Journal of the American Chemical Society, 136: 15122-15125, 2014

41. F. De Busserolles, N.J. Marshall and S.P. Collin, The eyes of lanternfishes (Myctophidae, Teleostei): novel ocular specialisations for vision in dim light, Journal of Comparative Neurology, 522: 1618-1640, 2014

48. K.A. Dyl, J.S. Cleverley, P.A. Bland, C.G. Ryan, L.A. Fisher and R.M. Hough, Quantified, whole section trace element mapping of carbonaceous chondrites by Synchrotron X-ray Fluorescence Microscopy: 1. CV meteorites, Geochimica et Cosmochimica Acta, 134: 100-119, 2014

49. P.K. Eggers, E. Eroglu, T. Becker, X. Chen, K. Vimalanathan, K.A. Stubbs, S.M. Smith and C.L. Raston, Nitrate uptake by p-phosphonic acid or p- (trimethylammonium)methyl calix[8]arene stabilized laminar materials, RSC Advances, 4: 48348, 2014

50. K.A. Evans, M. Darby Dyar, S.M. Reddy, A. Lanzirotti, D.T. Adams and N. Tailby, Variation in XANES in biotite as a function of orientation, crystal composition, and metamorphic history, American Mineralogist, 99: 443-457, 2014

51. K.A. Evans, A.G. Tomkins, J.B. Cliff and M.L. Fiorentini, Insights into subduction zone sulfur recycling from isotopic analysis of eclogite-hosted sulfides, Chemical Geology, 265: 1-19, 2014

52. M. Faull, S.Y.L. Ching, A.I. Jamolowicz, J. Beilby and P.K. Panegyres, Comparison of two methods for the analysis of CSF Abeta and tau in the diagnosis of Alzheimer’s disease, American Journal of Neurodegenerative Disease, 3(3): 143-151, 2014

53. P.M. Finch, E.S. Drummond, L.F. Dawson, J.K. Phillips and P.D. Drummond, Up-regulation of cutaneous alpha1-adrenoceptors in complex regional pain syndrome type 1, Pain Medicine, 15: 1945-1956, 2014

54. S.A. Fisher, A. Cleaver, D.D. Lakhiani, A. Khong, T. Connor, B. Mylie, W.J. Lesterhuis, B.W.S. Robinson and R.A. Lake, Neoadjuvant anti-tumor vaccination prior to surgery enhances survival , Journal of Translational Medicine, 12(245): 1-9, 2014

42. G.B. Deacon, R. Harika, P.C. Junk, B.W. Skelton, D. Werner and A.H. White, The synthesis, structures and polymorphism of the dimeric trivalent rare-earth 3,5-Dimethylpyrazolate complexes [Ln(Me2pz)3(thf)]2, European Journal of Inorganic Chemistry, 14: 2412-2419, 2014

43. M.P. Doublier, N. Thébaud, M.T.D. Wingate, S.S. Romano, C.L. Kirkland, K. Gessner, D.R. Mole and N. Evans, Structure and timing of Neoarchean gold mineralization in the Southern Cross district (Yilgarn Craton, Western Australia) suggest leading role of late Low-Ca I-type granite intrusions, Journal of Structural Geology, 67: 205-221, 2014

44. E.S. Drummond, L.F. Dawson, P.M. Finch, W. Li, T-Z. Guo, W.S. Kingery and P.D. Drummond, Increased bilateral expression of alpha1-adrenoceptors on peripheral nerves, blood vessels and keratinocytes does not account for pain or neuroinflammatory changes after distal tibia fracture in rats, Neuroscience, 281: 99-109, 2014

45. P.D. Drummond, E.S. Drummond, L.F. Dawson, V. Mitchell, P.M. Finch, C.W. Vaughan and J.K. Phillips, Upregulation of a1-adrenoceptors on cutaneous nerve fibres after partial sciatic nerve ligation and in complex regional pain syndrome type II, PAIN, 155: 606-616, 2014

46. E.S. Drummond, L.F. Dawson, P.M. Finch, G.J. Bennett and P.D. Drummond, Increased expression of cutaneous a1-adrenoceptors after chronic constriction injury in rats, The Journal of Pain, 15(2): 188-196, 2014

47. J.M. Duyvestyn, S.J. Taylor, S.A. Dagger, M. Orandle, H.C. Morse III, C.B.F. Thien and W.Y. Langdon, Dasatinib targets B-lineage cells but does not provide an effective therapy for myeloproliferative disease in c-Cbl RING finger mutant mice, PLOS ONE, 9(4): e94717 (1-10), 2014


55. T. Foster, J.A. Short, J.L. Falter, C. Ross and M.T. McCulloch, Reduced calcification in Western Australian corals during anomalously high summer water temperatures, Journal of Experimental Marine Biology and Ecology, 461: 133-143, 2014

56. R.O. Fuller, K.L. Livesey, R.C. Woodward, A.J. McKinley, B.W. Skelton, G.A. Koutsantonis and A.H. White, Magnetic studies of metal ion coordination clusters encapsulated with thiacalixarene, Australian Journal Chemistry, 67: 1588-1594, 2014

57. B. Fu, J.B. Cliff and R.E. Zartman, Zircon oxygen isotopic constraints from plutonic rocks on the magmatic and crustal evolution of the northern Appalachians in southern New England, USA, Canadian Journal of Earth Science, 51: 485-499, 2014

58. J.J. Lee, A.N. Sobolev, M.J. Turner, R.O. Fuller, B.B. Iversen, G.A. Koutsantonis and M.A. Spackman, Molecular imprisonment: Host response to guest location, orientation and dynamics in clathrates of Dianin’s compound, Crystal Growth & Design, 14: 1296-1306, 2014

59. F. Furfaro, E.S.M. Ang, R.R. Lareu, K. Murray and M. Goonewardene, A histological and micro-CT investigation in to the effect of NGF and EGF on the periodontal, alveolar bone, root and pulpal healing of replanted molars in a rat model - a pilot study, Progress in Orthodontics, 15(2): 1-12, 2014

60. M.N. Gandy, C.L. Raston and K.A. Stubbs, Towards aryl C–N bond formation in dynamic thin films, Organic Biomolecular Chemistry, 12: 4594, 2014

61. F. Giacometti, K.A. Evans, G. Rebay, J.B. Cliff, A.G. Tomkins, P. Rossetti, G. Vaggelli and D.T. Adams, Sulfur isotope evolution in sulfide ores from Western Alps: Assessing the influence of subduction-related metamorphism, Geochemistry Geophysics Geosystems, 15: 3808-3829, 2014

62. M.M. Giangregorio, B. Dastmalchi, A. Suvorova, G.V. Bianco, K. Hingerl, G. Brunoa and M. Losurdo, Effect of Interface energy and electron transfer on shape, plasmon resonance and SERS activity of supported surfactant-free gold nanoparticles, RSC Advances, 4: 29660, 2014

63. P. Gong, R.A. McLaughlin, Y. Liew, P.R.T. Munro, F.M. Wood and D.D. Sampson, Assessment of human burn scars with optical coherence tomography by imaging the attenuation coefficient of tissue after vascular masking, Journal of Biomedical Optics, 19(2): 021111 (1-10), 2014

64. P. Gong, L. Chin, S. Es’Haghian, Y. Liew, F.M. Wood, D.D. Sampson and R.A. McLaughlin, Imaging of skin birefringence for human scar assessment using polarization-sensitive optical coherence tomography aided by vascular masking, Journal of Biomedical Optics, 19(12): 126014 (1-10), 2014

65. I.D. Greene, F. Mastaglia, B.P. Meloni, K.A. West, J. Chieng, C.J. Mitchell, W-P. Gai and S. Boulos, Evidence that the LRRK2 ROC domain Parkinson’s disease-associated mutants A1442P and R1441C exhibit increased intracellular degradation, Journal of Neuroscience Research, 92: 506-516, 2014

66. D.J. Gregg, Z. Zhang, G.J. Thorogood, B.J. Kennedy, J.A. Kimpton, G.J. Griffiths, P.R. Guagliardo, G.R. Lumpkin and E.R. Vance, Cation antisite disorder in uranium-doped gadolinium zirconate pyrochlores, Journal of Nuclear Materials, 452(1-3): 474-478, 2014

67. Y. Guan, I.A. Malecki, P.A.R. Hawken, M.D. Linden and G.B. Martin, Under-nutrition reduces spermatogenic efficiency and sperm velocity, and increases sperm DNA damage in sexually mature male sheep, Animal Reproduction Science, 149: 163-172, 2014

68. C.K. Hagen, P.R.T. Munro, M. Endrizzi, P.C. Diemoz and A. Olivo, Low-dose phase contrast tomography with conventional x-ray sources, Medical Physics, 41: 070701 (1-6), 2014

69. M.T. Hill and M.C. Gather, Advances in small lasers, Nature Photonics, 8: 908-918, 2014

70. N. Hondow and R.O. Fuller, The use of preformed nanoparticles in the production of heterogeneous catalysts, Journal of Colloid and Interface Science, 417: 396-401, 2014

71. J. Huang, W.L. Griffin, Y. Gréau, N.J. Pearson, S.Y. O’Reilly, J.B. Cliff and L. Martin, Unmasking xenolithic eclogites: Progressive metasomatism of a key Roberts Victor sample, Chemical Geology, 364: 56-65, 2014

72. Y. Huang, W.B. de Boer, L.A. Adams, G. MacQuillan, M.K. Bulsara and G.P Jeffrey, Image analysis of liver biopsy samples measures fibrosis and predicts clinical outcome, Journal of Hepatology, 61: 22-27, 2014

73. P. Huot, T.H. Johnston, K.D. Lewis, J.B. Koprich, M.G. Reyes, S.H. Fox, M. J. Piggott and J.M. Brotchie, UWA-121, a mixed dopamine and serotonin re-uptake inhibitor, enhances L-DOPA anti-parkinsonian action without worsening dyskinesia or psychosis-like behaviours in the MPTP-lesioned common marmoset, Neuropharmacology, 82: 76-87, 2014

74. E.S. Ingham, N. Cook, J.B. Cliff, C.L. Ciobanu and A. Huddleston, A combined chemical, isotopic and microstructural study of pyrite from roll-front uranium deposits, lake eyre basin, South Australia, Geochimica et Cosmochimica Acta, 125: 440-465, 2014

75. M. Ireland, X. Wang, T. Radomirovic, P. Smith and F. Jones, Investigating the impact of anatase on the dissolution of boehmite, Hydrometallurgy, 147-148: 246-254, 2014

cmca.uwa.edu.au 33

76. N.M. Jaafar, P.L. Clode and L.K. Abbott, Microscopy observations of habitable space in biochar for colonization by fungal hyphae from soil, Journal of Integrative Agriculture, 13(3): 483–490, 2014

77. S. Jensen, S. Samanta, S. Chakrabarti-Bell, K. Regenauer-Lieb, K.H.M. Siddique and S. Wang, Automated thresholding and analysis of microCT scanned bread dough, Journal of Microscopy, 256(2): 100-110, 2014

78. S.S. Kampmann, A.N. Sobolev, G.A. Koutsantonis and S.G. Stewart, Stable nickel(0) phosphites as catalysts for C-N cross-coupling reactions, Advanced Synthesis & Catalysis, 356: 1967-1973, 2014

79. B.F. Kennedy, K.M. Kennedy and D.D. Sampson, A review of optical coherence elastography: Fundamentals, techniques and prospects, IEEE Journal of Selected Topics in Quantum Electronics, 20(2): 7101217 (1-17), 2014

80. B.F. Kennedy, R.A. McLaughlin, K.M. Kennedy, L. Chin, A. Curatolo, A. Tien, B.B. Latham, C.M. Saunders and D.D. Sampson, Optical coherence micro-elastography: Mechanical-contrast imaging of tissue microstructure, Biomedical Optics Express, 5(7): 2113-2124, 2014

81. B. Kennedy, F.G. Malheiro, L. Chin and

D.D. Sampson, Three-dimensional

optical coherence elastography

by phase-sensitive comparison of

C-scans, Journal Of Biomedical Optics,

19(7): 076006 (1-7), 2014

82. K.M. Kennedy, S. Es’haghian, L. Chin, R.A. McLaughlin, D.D. Sampson and B.F. Kennedy, Optical palpation: Optical coherence tomography-based tactile imaging using a compliant sensor, Optics Letters, 39(10): 3014-3017, 2014

83. A. Khong, A.L. Cleaver, M.F. Alatas, B.C. Mylie, T. Connor, S.A. Fisher, S. Broomfield, W.J. Lesterhuis, A.J. Currie, R. A. Lake and B.W. Robinson, The efficacy of tumor debulking surgery is improved by adjuvant immunotherapy using imiquimod and anti-CD40, BMC Cancer, 14(969): 1-9, 2014

91. S. Kwang and P. Abbott, The presence and distribution of bacteria in dentinal tubules of root filled teeth, International Endodontic Journal, 47(6): 600-610, 2014

92. W. Lei, R.J. Gu, J. Antoszeweki, J. Dell, and L. Faraone, GaSb: A New Alternative Substrate for Epitaxial Growth of HgCdTe, Journal of Electronic Material, 43(8): 2788-2794, 2014

93. G. Li, Y. Ma, T.S. Cheng, E. Landao-Bassonga, A. Qin, N.J. Pavlos, C. Zhang, Q. Zheng and M.H. Zheng, Identical subchondral bone microarchitecture pattern with increased bone resorption in rheumatoid arthritis as compared to osteoarthritis, Osteoarthritis and Cartilage, 22: 2083-2092, 2014

94. X.P. Li, C.W. Kang, H. Huang and T.B. Sercombe, The role of a low-energy–density re-scan in fabricating crack-free Al85Ni5Y6Co2Fe2 bulk metallic glass composites via selective laser melting, Materials and Design, 63: 407-411, 2014

95. X.P. Li, C.W. Kang, H. Huang, L.C. Zhang and T.B. Sercombe, Selective laser melting of an Al86Ni6Y4.5Co2La1.5 metallic glass: Processing, microstructure evolution and mechanical properties, Materials Science & Engineering A, 606: 370-379, 2014

96. B. Li, L. Bagas and F. Jourdan, Tectono-thermal evolution of the Palaeoproterozoic Granites–Tanami Orogen, North Australian Craton: Implications from hornblende and biotite 40Ar/39Ar geochronology, Lithos, 206-207: 262-276, 2014

97. I. Ling, B.W. Skelton, A.N. Sobolev, Y. Aliasa and C.L. Raston, Manipulating the conformation and interplay of p-sulfonated calix[4]arenes by lower rim trisubstitution with N′-cyanocarbamimidate groups, CrystEngComm, 16: 5159-5164, 2014

98. I. Ling, A.N. Sobolev, R. Hashim and J.M. Harrowfield, Stereochemistry of cage amine complexes - probing the ligand conformational flexibility with hydrogen bonds, CRYSTENGCOMM, 16(48): 11058-11063, 2014

84. K.L. Kilminster, F.J. Lincoln and B.W. Skelton, A barium vanadium(V) selenite hydrate, Ba(VO2)2(SeO3)2.H2O: A novel 3D polymer of cross-linked sheets with embedded ...V–O–V... 21 Helices*, Australian Journal Chemistry, 67: 1878-1881, 2014

85. R.Q. Kim, W.A. Offen, G.J. Davies and K.A. Stubbs, Structural enzymology of Helicabacter. pylon methylthioadenosine nucleosidase in the futalosine pathway, Acta Crystrallography, Section D. Biological Chemistry: 177, 2014

86. B.R. Klyen, L. Scolaro, T. Shavlakadze, M.D. Grounds and D.D. Sampson, Optical coherence tomography can assess skeletal muscle tissue from mouse models of muscular dystrophy by parametric imaging of the attenuation coefficient, Biomedical Optics Express, 5(4): 1217-1262, 2014

87. W. Koh, A. Thompson, H. Edwards, P. Monis and P.L. Clode, Extracellular excystation and development of Cryptosporidium: tracing the fate of oocysts within Pseudomonas aquatic biofilm systems, BMC Microbiology, 14(281): 1-14, 2014

88. G.A. Koutsantonis, P.J. Low, C.F.R. Mackenzie, B.W. Skelton and D.S. Yufit, Coordinating tectons: Bimetallic complexes from bipyridyl terminated group 8 alkynyl complexes, Organometallics, 33(18): 4911- 4922, 2014

89. J. Kular, J.C. Tickner, N.J. Pavlos, H.M. Viola, T. Abel, B.S. Lim, X. Yang, H. Chen, R. Cook, L.C. Hool, M.H. Zheng and J. Xu, Choline kinase beta mutant mice exhibit reduced phosphocholine, elevated osteoclast activity and low bone mass, The Journal of Biological Chemistry, 290(3): 1729-1742, 2014

90. C. Külheim, C.G. Jones, J.A. Plummer, E.L. Ghisalberti, L. Barbour and J. Bohlmann, Foliar application of methyl jasmonate does not increase terpenoid accumulation, but weakly elicits terpenoid pathway genes in sandalwood (Santalum album L.) seedlings, Plant Biotechnology , 31: 585-594, 2014


99. L. Liu, Z. Shao, H.M. Ang, M.O. Tade and S. Liu, Are microorganisms indispensable in green microbial nanomaterial synthesis?, RCS Advances, 4(28): 14564-14568, 2014

100. D. Lorenser, C.C. Singe, A. Curatolo and D.D. Sampson, Energy-efficient low-Fresnel-number Bessel beams and their application in optical coherence tomography, Optics Letters, 39(3): 548-551, 2014

101. M. Losurdo, C. Yi, A. Suvorova, S. Rubanov, T-H. Kim, M.M. Giangregorio, W. Jiao, I. Bergmair, G. Bruno and A.S. Brown, Demonstrating the capability of the high-performance plasmonic gallium - graphene couple, ACS NANO, 8(3): 3031-3041, 2014

102. Y-B. Luo, C. Mitrpant, A.M. Adams, R.D. Johnsen, S. Fletcher, F.L. Mastaglia and S.D. Wilton, Antisense oligonucleotide induction of progerin in human myogenic cells, PLOS ONE, 9(6): e98306 (1-9), 2014

103. M. Luo, Z-Q. Chen, L. Zhao, S. Kershaw, J. Huang, L. Wu, H. Yang, Y. Fang, Y. Huang, Q. Zhang, S. Hu, C. Zhou, W. Wen and Z. Jia, Early Middle Triassic stromatolites from the Luoping area, Yunnan Province, Southwest China: Geobiologic features and environmental implications, Palaeogeography, Palaeoclimatology, Palaeoecology, 412: 124-140, 2014

104. I. Lozic, C.A. Bartlett, J.A. Shaw, K. Swaminathan Iyer, S.A. Dunlop, M.R. Kilburn and M. Fitzgerald, Changes in subtypes of Ca microdomains following partial injury to the central nervous system, Metallomics, 6: 455-464, 2014

105. H. Lu, R.A. Boulos, B.C.Y. Chan, C.T. Gibson, X. Wang, C.L. Raston and H.T. Chua, Carbon nanofibres from fructose using a light-driven high-temperature spinning disc processor, Chemical Communications, 50: 1478-1480, 2014

106. L.L. Machuca, R. Jeffrey, S.I. Bailey, R. Gubner, E.L.J. Watkin, M.P. Ginige, A.H. Kaksonen and K. Heidersbach, Filtration-UV irradiation as an option for mitigating the risk of microbiologically influenced corrosion of subsea construction alloys in seawater, Corrosion Science, 79: 89-99, 2014

107. C.Macias–Romero, P.R.T. Munro and P. Torok, Polarization–multiplexed encoding at nanometer scales, Optics Express, 22(21): 26240-26245, 2014

108. C.Macías-Romero, M.R. Foreman, P.R.T. Munro and P. Török, Confocal polarization imaging in high-numerical-aperture space, Optics Letters, 39(8): 2322-2325, 2014

109. Y. Ma, M. Zhu and D. Zhang , Effect of a homogeneous combustion catalyst on the characteristics of diesel soot emitted from a compression ignition engine, Applied Energy , 113: 751–757, 2014

110. L.A.J. Martin, J. Hermann, L. Gauthiez-Putallaz, D.L. Whitney, A. Vitale-Brovarone, K.F. Fornash and N.J. Evans, Lawsonite geochemistry and stability - implication for trace element and water cycles in subduction zones, Journal of Metamorphic Geology, 32(5): 455-478, 2014

111. Maskell, P. Duuring and S.G. Hagemann, Hydrothermal alteration events controlling magnetiterich iron ore at the Matthew Ridge prospect, Jack Hills greenstone belt, Yilgarn Craton, Australian Journal of Earth Sciences, 61: 187-212, 2014

112. A.L. McGuire, N. Urosevic, D.T. Chan, G. Dogra, T.J.J. Inglis and A. Chakera, The impact of chronic kidney disease and short-tern treatment with rosiglitazone on plasma cell-free DNA levels, PPAR Research, Article ID 643189: 1-8, 2014

113. R. McKeone, M. Wikstrom, C. Kiel and P.E. Rakoczy, Assessing the correlation between mutant rhodopsin stability and the severity of retinitis pigmentosa, Molecular Vision, 20: 183-199, 2014

114. R.A. McLaughlin, P.B. Noble and D.D. Sampson, Optical coherence tomography in respiratory science and medicine: from airways to alveoli, Physiology, 29(5): 302-303, 2014

115. R.E. Melchers, R.J. Jeffrey and K.M. Usher, Localized corrosion of steel sheet piling, Corrosion Science, 79: 139-147, 2014

116. J.Mo, K. Eggers, C.L. Raston and L.Y. Lim, Development and validation of a LC/TOF MS method for the determination of carboplatin and paclitaxel in nanovesicles, Analytical and Bioanalytical Chemistry, 406: 2659-2667, 2014

117. D.R. Mole, M.L. Fiorentini, N. Thebaud, K.F. Cassidy, T.C. McCuaig, C.L. Kirkland, S.S. Romano, M.P. Doublier, E.A. Belousova, S.J. Barnes and J. Miller, Archean komatiite volcanism controlled by the evolution of early continents, Proceedings of the National Academy of Sciences, 111(28): 10083-10088, 2014

118. J. Muhling, A. Suvorova and B. Rassmussen, The occurrence and composition of chevkinite-(Ce) and perrierite-(Ce) in tholeiitic intrusive rocks and lunar mare basalt, American Mineralogist, 99: 1911-1921, 2014

119. P.R.T. Munro, D. Engelke and D.D. Sampson, A compact source condition for modelling focused fields using the pseudospectral time-domain method, Optics Express, 22(5): 5599-5613, 2014

120. P.R.T. Munro, M. Endrizzi, P.C. Diemoz, C.K. Hagen, M.B. Szafraniec, T.P. Millard, C.E. Zapata, R.D. Speller and A. Olivo, Medicine, material science and security: the versatility of the coded-aperture approach, Philosophical Transactions of the Royal Society A, 372: 20130029, 2014

121. R.K. Nachimuthu, R.D. Jeffery, M. Martyniuk, R.C. Woodward, P.J. Metaxas, J.M. Dell and L. Faraone, Investigation of cerium-substituted europium iron garnets deposited by biased target ion beam deposition, IEEE Transactions on Magnetics, 50(12): 2201807 (1-7), 2014

cmca.uwa.edu.au 35

122. K-A.T. Nguyen, S.R. Clarke, J. Matisons, B.W. Skelton, A.H. White and E. Markovic, Synthesis of strictly alternating siloxane copolymers and cyclics, Silicon, 6: 21-26, 2014

123. S.J. Nichols and S.G. Hagemann, Structural and hydrothermal alteration evidence for two gold mineralisation events at the New Celebration gold deposits in Western Australia, Australian Journal of Earth Sciences, 61(1): 113-141, 2014

124. S. O’Brien, J.A. Shaw, X. Zhao, P.V. Abbott, P.R. Munroe, J. Xu, D. Habibi and Z. Xie, Size dependent elastic modulus and mechanical resilience of dental enamel, Journal of Biomechanics, 47(5): 1060-1066, 2014

125. C.D. O’Loughlin, C. Gaudin, J.P. Morton and D.J. White, MEMS accelerometers for measuring dynamic penetration events in geotechnical centrifuge tests, International Journal of Physical Modelling in Geotechnics, 14(2): 31- 39, 2014

126. S. Orbisaglia, C. Di Nicola, F. Marchetti, C. Pettinari, R. Pettinari, L.M.D.R.S. Martins, E.C.B.A. Alegria, M.F.C. Guedes da Silva, B.G.M. Rocha, M.L. Kuznetsov, A.J.L. Pombeiro, B.W. Skelton, A.N. Sobolev and A.H. White, New ruII(arene) complexes with halogen-substituted bis- and tris(pyrazol-1-yl)borate ligands, Chemistry - A European Journal, 20: 3689-3704, 2014

127. M. Pacton, D. Wacey, C. Corinaldesi, M. Tangherlini, M. Kilburn, G. Gorin, R. Danovaro and C. Vasconcelos, Viruses as a new agent of organomineralisation in the geological record, Nature Communications, 5: 1-9, 2014

128. A.V. Pan, O.V. Shcherbakova, S.A. Fedoseev, I.A. Golovchanskiy, D. Attard, S.K.H. Lam, J. Du, C.P. Foley, S. Rubanov and A. Suvorova, Enhancing properties of high temperature superconducting step-edge Josephson junctions by nano-multilayers with a small mismatch, Advanced Materials Interfaces, 1: 1300112 (1-6), 2014

135. F.J. Pollock, E.M. Wood-Charlson, M.J.H. van Oppen, D.G. Bourn, B.L. Willis and K.K.D. Weynberg, Abundance and morphology of virus-like particles associated with the coral Acropora hyacinthus differ between healthy and white syndrome-infected states, Marine Ecology Progress Series, 510: 39-43, 2014

136. E. Prakoso, J.E.E. Trinitz-Parker, A.D. Clouston, Z. Kayali, A. Lee, E.K. Gan, G.A. Ramm, J.G. Kench, D.G. Bowen, J.K. Olynyk, G.W. McCaughan and N.A. Shackel, Analysis of the intrahepatic ductular reaction and progentior cell responses in Hepatitis C virus recurrence after liver transplantation, Liver Transplantation, 20: 1508- 1519, 2014

137. C.A. Price, P.R.T. Munro and J.S. Weitz, Estimates of leaf vein density are scale dependent, Plant Physiology, 164: 173-180, 2014

138. K.A. Punch and M.J. Piggott, Total synthesis of monosporascone and dihydromonosporascone, Organic Biomolecular Chemistry, 12: 2801, 2014

139. B.C. Quirk, R.A. McLaughlin, A.M. Pagnozzi, B.F. Kennedy, P.B. Noble and D.D. Sampson, Optofluidic needle probe integrating targeted delivery of fluid with optical coherence tomography imaging, Optics Letters, 39(10): 2888-2891, 2014

140. B. Rasmussen, B. Krapez and D.B. Meier, Replacement origin for hematite in 2.5 Ga banded iron formation: Evidence for postdepositional oxidation of iron-bearing minerals, Geological Society of America Bulletin, 126(3-4): 438-446, 2014

141. B. Rasmussen, B. Krapez and J.R. Muhling, Hematite replacement of iron-bearing precursor sediments in the 3.46-b.y.-old Marble Bar Chert, Pilbara craton, Australia, Geologcal Society of America Bulletin, 126: 1245-1258, 2014

129. E. Paynter, B. Baer-Imhoof, M. Linden, T. Lee-Pullen, K. Heel, P. Rigby and B. Baer, Flow cytometry as a rapid and reliable method to quantify sperm viability in the Honeybee Apis mellifera, Cytometry Part A, 85A: 463-472, 2014

130. Y. Peng, T.F. Lee-Pullen, K. Heel, A.H. Millar and B. Baer, Quantifying spore viability of the honey bee pathogen Nosema apis using flow cytometry, Cytometry Part A, 85(5): 545-562, 2014

131. R. Pettinari, C. Pettinari, F. Marchetti, B.W. Skelton, A.H. White, L. Bonfil, M. Cuccioloni, M. Mozzicafreddo, V. Cecarini, M. Angeletti, M. Nabissi and A.M. Eleuteri, Arene−ruthenium(II) acylpyrazolonato complexes: apoptosis-promoting effects on human cancer cells, Journal of Medicinal Chemistry, 57: 4532- 4542, 2014

132. C. Pettinari, F. Marchetti, S. Orbisaglia, J. Palmucci, R. Pettinari, C. Di Nicola, B.W. Skelton and A.H. White, Synthesis, characterization, and crystal structures ofscorpionate complexes with the Hydrotris[3-(2 -thienyl)-pyrazol-1-yl]borate ligand, European Journal of Inorganic Chemistry, 2014: 546-558, 2014

133. S. Piek, Z. Wang, J. Ganguly, A.M. Lakey, S.N. Bartley, S. Mowlaboccus, A. Anandan, K.A. Stubbs,.M.J. Scanlon, A. Vrielink, P. Azadi, R.W. Carlson and C.M. Kahler, The role of oxidoreductases in determining the function of the neisserial lipid. A phosphoethanolamine transferase required for resistance to Polymyxin, PLOS ONE, 9: e106513, 2014

134. M. Pazos-Navarro, J.S. Croser, M. Castello, P. Ramankutty, K. Heel, D. Real, D.J. Walker, E. Correal and M. Dabauza, Embryogenesis and plant regeneration of the perennial pasture and medicinal legume Bituminaria bituminosa (L) C.H Stirton, Crop and Pasture Science, 65(9): 934-943, 2014


142. J.W. Reisser, J.A. Shaw, G.M. Hallegraeff, M.C. Proietti, D.K.A. Barnes, M. Thums, C.V. Wilcox, B.D. Hardesty and C.B. Pattiaratchi, Millimeter-sized marine plastics: A new pelagic habitat for microorganisms and invertebrates, PLOS ONE, 9(6): 1-11, 2014

143. G. Rizzotto, L.A. Hartmann, J.O.S. Santos and N.J. McNaughton, Tectonic evolution of the southern margin of the Amazonian craton in the late Mesoproterozoic based on field relationships and zircon U-Pb geochronology, Anais da Academia Brasileira de Ciências, 86(1): 57- 84, 2014

144. S.S. Romano, N.J.M. Thébaud, D.R. Mole, M.T.D. Wingate, C.L. Kirkland and M.P. Doublier, Geochronological constraints on nickel metallogeny in the Lake Johnston belt, Southern Cross Domain, Australian Journal of Earth Sciences, 61(1): 143-157, 2014

145. K.E. Saunders, B. Buse, M.R. Kilburn, S.L. Kearns and J.D. Blundy, Nanoscale characterisation of crystal zoning, Chemical Geology, 364: 20-32, 2014

146. A.Scaffidi, M.T. Waters, Y.K. Sun, B.W. Skelton, K.W. Dixon, E.L. Ghisalberti, G.R. Flematti, and S.M. Smith, Strigolactone hormones and their stereoisomers signal through two related receptor proteins to induce different physiological responses in rabidopsis, Plant Physiology, 165: 1221-1232, 2014

147. M. Schmieder, F. Jourdan, E. Tohver and E.A. Cloutis, 40Ar/39Ar age of the Lake Saint Martin impact structure (Canada) – Unchaining the Late Triassic terrestrial impact craters, Earth and Planetary Science Letters, 406: 37-48, 2014

148. L. Scolaro, R.A. McLaughlin, B.F. Kennedy, C.M. Saunders and D.D. Sampson, A review of optical coherence tomography in breast cancer, Photonics & Lasers in Medicine, 3(3): 225-240, 2014

149. Y. Shen, S.L. Redmond, J.M. Papadimitriou, B.M. Teh, S. Yan, Y. Wang, M.D. Atlas, R.J. Marano, M. Zheng and R.J. Dilley, The biocompatibility of silk fibroin and acellular collagen scaffolds for tissue engineering in the ear, Biomedical Materials, 9: 015015 (1-12), 2014

150. S. Shi, Z. Sun, X. Hu and H. Chen, Flexural strength and energy absorption of carbon-fiber–aluminum honeycomb composites and sandwich reinforced by aluminum grid, Thin-Walled Structures, 84: 416-422, 2014

151. S. Shi, Z. Sun, X. Hu and H. Chen, Carbon-fiber and aluminum-honeycomb sandwich composites with and without Kevlar-fiber interfacial toughening, Composites Part A, 67: 102-110, 2014

152. A.Y. Sim, K.E. Wallman, T.J. Fairchild and K.J. Guelfi, High-intensity intermittent exercise attenuates ad-libitum energy intake, International Journal of Obesity, 38: 417-422, 2014

153. A.K. Singh, B. Pluvinage, M.A. Higgins, A.B. Dalia, S. Woodiga, M. Flynn, A.R. Lloyd, J.N. Weiser, K.A. Stubbs, A.B. Boraston and S.J. King, Unraveling the multiple functions of the architecturally intricate Streptococcus pneumoniae β-galactosidase, BgaA, PLOS Pathogens, 10: e1004364, 2014

154. L. Su, C. Lu, G.Y. Deng, K.A. Tieu, L.C. Zhang, P.R. Guagliardo, S.N. Samarin and J.F. Williams, Vacancy-type defects study on ultra-fine grained aluminium processed by severe plastic deformation, Science of Advanced Materials, 6(7): 1338-1345, 2014

155. R. Sulpice, H. Ishihara, A. Schlereth, G.R. Cawthray, B. Encke, P. Giavalisco, A. Ivakov, S. Arrivault, R. Jost, N. Krohn, J. Kuo, E. Laliberté, Stuart J. Pearse, J.A. Raven, W-R. Scheible, F. Teste, E.J. Veneklaas, M. Stitt and H. Lambers, Low levels of ribosomal RNA partly account for the very high photosynthetic phosphorus-use efficiency of Proteaceae species, Plant Cell and Environment, 37: 1276- 1297, 2014

156. H. Sun, C.K. Kwan, A. Suvorova, H.M. Ang, M.O. Tadé and S. Wang, Catalytic oxidation of organic pollutants on pristine and surface nitrogen-modified carbon nanotubes with sulfate radicals, Applied Catalysis B: Environmental, 154-155: 134-141, 2014

157. H. Sun, G. Zhou, Y. Wang, A. Suvorova and S. Wang, A new metal-free carbon hybrid for enhanced photocatalysis, Applied Materials and Interfaces, 6: 16745-16754, 2014

158. Z. Sun, S. Shi , X. Hu, X. Guo, J. Chen and H. Chen, Short-aramid-fiber toughening of epoxy adhesive joint between carbon fiber composites and metal substrates with different surface morphology, Composites Part B, 77: 38-45, 2014

159. Z. Sun, X. Hu and H. Chen, Effects of aramid-fibre toughening on interfacial fracture toughness of epoxy adhesive joint between carbon-fibre face sheet and aluminium substrate, International Journal of Adhesion and Adhesives, 48: 288-294, 2014

160. X. Sun, A. Keating and G. Parish, Released micromachined beams utilizing laterally uniform porosity porous silicon, Nanoscale Research Letters, 9: 426 (1-7), 2014

161. Z. Sun, S. Shi, X. Hu, H. Chen and Z. Wong, Adhesive joints between carbon fiber and aluminum foam reinforced by surface-treated aramid fibers, Polymer Composites, 36: 192-197, 2014

162. R. Thorne, R. Anand and A. Suvorova, The formation of fluvio-lacustrine ferruginous pisoliths in the extensive palaeochannels of the Yilgarn Craton, Western Australia, Sedimentary Geology, 313: 32-44, 2014

163. C.L. Tong, E. Eroglu and C.L. Raston, In situ synthesis of phosphate binding mesocellular siliceous foams impregnated with iron oxide nanoparticles, RCS Advances, 4: 46718-46722, 2014

cmca.uwa.edu.au 37

164. A.A. Tonkikh, N.D. Zakharov, A.A. Suvorova, C. Eisenschmidt, J. Schilling and P. Werner, Cubic phase Sn-Rich GeSn nanocrystals in a Ge matrix, Crystal Growth & Design, 14: 1617- 1622, 2014

165. J. Toster, I. Kusumawardani, E. Eroglu, K.S. Iyer, F. Roseic and C.L. Raston, Superparamagnetic imposed diatom frustules for the effective removal of phosphates, Green Chemistry, 16: 82-85, 2014

166. S.R. Tridico, P.J. Rigby, K.P. Kirkbride, J. Haile and M.A. Bunce, Megafaunal split ends: Microscopical characterisation of hair structure and function in extinct woolly mammoth and woolly rhino, Quaternary Science Reviews, 83: 68-75, 2014

167. K.M. Usher, A.H. Kaksonen and I.D. MacLeod, Marine rust tubercles harbour iron corroding archaea and sulphate reducing bacteria, Corrosion Science, 83: 189-197, 2014

168. K.M. Usher, A.H. Kaksonen, I. Cole and D. Marney, Critical review: Microbially influenced corrosion of buried carbon steel pipes, International Biodeterioration & Biodegradation, 93: 84-106, 2014

169. I.O. Usov, S. Rubanov, J. Won and A.A. Suvorova, Transformation of YSZ under high fluence argon ion implantation, Nuclear Instruments and Methods in Physics Research Section B, 326: 283-288, 2014

170. J.G. Vaughan, B.L. Reid, P.J. Wright, S. Ramchandani, B.W. Skelton, P. Raiteri, S. Muzzioli, D.H. Brown, S. Stagni and M. Massi, Photophysical and photochemical trends in tricarbonyl rhenium(I) Nheterocyclic carbene complexes, Inorganic Chemistry, 53: 3629-3641, 2014

171. K. Vin Tan, P.A. Pellegrini, B.W. Skelton, C.F. Hogan, I. Greguric and P.J. Barnard, Triamidetriamine bearing macrobicyclic and macrotricyclic ligands: Potential applications in the development of copper-64 radiopharmaceuticals, Inorganic Chemistry, 53: 468-477, 2014

180. X.J. Wang, L.C. Zhang, M.H. Fang and T.B. Sercombe, The effect of atmosphere on the structure and properties of a selective laser melted Al–12Si alloy, Materials Science & Engineering A, 597: 370-375, 2014

181. C. Weis, F. Blank, A. West, G. Black, R.C. Woodward, M.R.J. Carroll, R. Kartmann, E. Hallam, J.A. Shaw, J. Murphy, W.Y. Teoh, K.E. Aifantis, R. Amal, M. House, T. St Pierre and B. Fabry, Labeling of cancer cells with magnetic nanoparticles for magnetic resonance imaging, Magnetic Resonance in Medicine, 71: 1896- 1905, 2014

182. W. Wei, Z. Wan and W. Chen, A facile synthesis strategy for structural property control of mesoporous alumina and its effect on catalysis for biodiesel production, Advanced Powder Technology, 25(4): 1220- 1226, 2014

183. W. Weiyong, P.K. Shen and S.P. Jiang, Controllable synthesis of graphene supported MnO2 nanowires via self-assembly for enhanced water oxidation in both alkaline and neutral solutions, Journal of Materials Chemistry A, 2(1): 123-129, 2014

184. A.J.R. White, M. Legras, R.E. Smith and P. Nadoll, Deformation-driven, regional-scale metasomatism in the Hamersley Basin, Western Australia, Journal of Metamorphic Geology, 32(4): 417-433, 2014

185. J.F. Williams, S.N. Samarin, O. Targhagh, A. Hilton, K. Sudarshan, P.R. Guagliardo, L. Praviça and O.M. Artamonov, Scattering of free electrons by free electrons, Physical Review A (Atomic, Molecular and Optical Physics), 89(6): 062717 (1- 6), 2014

186. X. Yang, D. Lorenser, R.A. McLaughlin, R.W. Kirk, M. Edmond, M.C. Simpson, M.D. Grounds and D.D. Sampson, Imaging deep skeletal muscle structure using a high-sensitivty ultrathin side-viewing optical coherence tomography needle probe, Biomedical Optics Express, 5(1): 136-148, 2014

172. A.Vitale-Brovarone, O. Alard, O. Beyssac, L.A.J. Martin and M. Picatto, Lawsonite metasomatism and trace element recycling in subduction zones, Journal of Metamorphic Geology, 32(5): 489-514, 2014

173. Z. Vukmanovic, S.M. Reddy, B. Godel, S.J. Barnes, M.L. Fiorentini, S.J. Barnes and M.R. Kilburn, Relationship between microstructures and grain-scale trace element distribution in komatiite-hosted magmatic sulphide ores, Lithos, 184-187: 42-61, 2014

174. D. Wacey, N. McLoughlin, M. Saunders and C. Kong, The nano-scale anatomy of a complex carbon-lined microtube in volcanic glass from the ~92 Ma Troodos Ophiolite, Cyprus, Chemical Geology, 363: 1-12, 2014

175. D. Wacey, M. Saunders, J. Cliff, M.R. Kilburn, C. Kong, M.E. Barley and M.D. Brasier, Geochemistry and nano-structure of a putative ∼3240million-year-old black smoker biota, Sulphur Springs Group, Western Australia, Precambrian Research, 249: 1-12, 2014

176. D. Wacey, M. Saunders, M. Roberts, S. Menon, L. Green, C. Kong, T. Culwick, P. Strother and M.D. Brasier, Enhanced cellular preservation by clay minerals in 1 billion-year-old lakes, Scientific Reports, 4: 5841 (1-11), 2014

177. Z. Wan, W. Wu, W. Chen, H. Yang and D. Zhang, Direct synthesis of hierarchical ZSM5 zeolite and its performance in catalyzing methanol to gasoline conversion, Industrial & Engineering Chemistry Research, 53: 19471−19478, 2014

178. X.D. Wang, R.G. McDonald, R.D. Hart, J. Li and A. van Riessen, Acid resistance of goethite in nickel laterite ore from Western Australia. Part II. Effect of liberating cementations on acid leaching performance, Hydrometallurgy, 141: 49-58, 2014

179. A.Y. Wang, Y. Shen, J.T. Wang, P.L. Friedland, M.D. Atlas and R.J. Dilley, Animal models of chronic tympanic membrane perforation: A ‘time-out’ to review evidence and standardize design, International Journal of Pediatric Otorhinolaryngology, 78: 2048-2055, 2014


194. C.Y. Yin, M-F. Ng, M. Saunders, B-M. Goh, G. Senanayake, A. Sherwood and M. Hampton, New insights into the adsorption of aurocyanide ion on activated carbon surface: electron microscopy analysis and computational studies using fullerene-like models, Langmuir, 30: 7703- 7709, 2014

195. W. Zang, X. Chen, R.A. Boulos, J. Tosterb and C.L. Raston, Hydrogen induced p-phosphonic acid calix[8]arene controlled growth of Ru, Pt and Pd nanoparticles, Chemical Communications, 50: 15167- 15170, 2014

196. Y. Zhang, A.D.J. van Dijk, A. Scaffidi, G.R. Flematti, M. Hofmann, T. Charnikhova, F. Verstappen, J. Hepworth, S. van der Krol, O. Leyser, S.M. Smith, B. Zwanenburg, S. Al-Babili, C. Ruyter-Spira and H.J. Bouwmeester, Rice cytochrome P450 MAX1 homologs catalyze distinct steps in strigolactone biosynthesis, Nature Chemical Biology, 10: 1028-1033, 2014

197. X. Zhang, Z. Sun and X. Hu, Low temperature fracture toughness of PMMA and crack-tip conditions under flat-tipped cylindrical indenter, Polymer Testing, 38: 57-63, 2014

198. Zhelezinskaia, A.J. Kaufman, J. Farquhar and J. Cliff, Large sulfur isotope fractionations associated with Neoarchean microbial sulfate reduction, Science, 346(6210): 742-744, 2014

199. Zhukova, H. StC O’Neill, I.H. Cambell and M.R. Kilburn, The effect of silica activity on the diffusion of Ni and Co in olivine, Contributions to Mineralogy and Petrology, 168: 1029 (1-15), 2014

187. J. Yang, R. Sultana and X. Hu, Novel layered hydroxyapatite/tri-calcium phosphate–zirconia scaffold composite with high bending strength for load-bearing bone implant application, International Journal of Applied Ceramic Technology, 11(1): 23-30, 2014

188. L. Yasmin, P.K. Eggers, B.W. Skelton, K.A. Stubbs and C.L. Raston, Thin film microfluidic synthesis of fluorescent highly substituted pyridines, Green Chemistry, 16: 3450-3453, 2014

189. L. Yasmin, K.A. Stubbs and C.L. Raston, Vortex fluidic promoted Diels–Alder reactions in an aqueous medium, Tetrahedron Letters, 55: 2246–2248, 2014

190. N.J. Yates, M.T. Martin-Iverson and J. Rodger, The role of ephrin-A2 and ephrin-A5 in sensorimotor control and gating, Behavioural Brain Research, 275: 225-233, 2014

191. W. Yi, Z. Sun, D Niu and X. Lu, In vitro bioactivity of 3D Ti-mesh with bioceramic coatings insimulated body fluid, Journal of Asian Ceramic Societies, 2: 210-214, 2014

192. W. Yi, X. Sun, D. Niu and X. Hu, Characteristics of Micro-Gold-Particle/glass-ceramic composite from post-sintering thermal treatment, Journal of Ceramic Science and Technology, 5(1): 45-50, 2014

193. W. Yi, X. Hu, X. Sun, P. Ichim and A. Suvorova, Processing and properties of bioceramic coatings onto 3D Ti-mesh by dipcasting method, International Journal of Applied Ceramic Technology, 11(6): 1030-1038, 2014

2015 Journal papers

Total 208Biological Sciences 33Earth Sciences 39Biomedical Sciences 47Physical Sciences 89

2015Book chapters

1. H. Lambers, P.L. Clode, H-J. Hawkins, E. Lalibert e, R.S. Oliveira, P. Reddell, M.W. Shane, M. Stitt and P. Weston, Metabolic adaptations of the non-mycotrophic proteaceae to soils with low phosphorus availability, In: Annual Plant Reviews, Vol. 48: 289-336, 2015

2. D. Lorenser, R.A. McLaughlin and D.D. Sampson, Optical coherence tomography in a needle format, In: Optical Coherence Tomography Technology and Applications, Vol. 2: 2413-2472, 2015

3. W. Sato-Okoshi, H. Abe, K. Okoshi, W. Teramoto, J. Shaw, B–S. Koh, Y-H. Kim, J-S. Hong and J-Y. Li, Harmful shell borers, Polydora species (Polychaeta: Spionidae), from commercially important mollusk Shells in East Asia and Australia, In: Marine Productivity: Perturbations and Resilience of Socio-ecosystems, 31-42, 2015

4. B.F. Kennedy, K.M. Kennedy, A.L. Oldenburg, S.G. Adie, S.A. Boppart and D.D. Sampson, Optical Coherence Elastography, In: Optical Coherence Tomography, Technology and Applications, Vol. 2: 1007-1054, 2015

5. M.R. Kilburn and D. Wacey, Nanoscale secondary ion mass spectrometry (NanoSIMS) as an analytical tool in the geosciences, In: Principles and Practice of Analytical Techniques in Geosciences, 1-34, 2015

6. D. Wacey, Early Life on Earth, In: Encyclopedia of Scientific Dating Methods. 229-234, 2015

7. D. Wacey, In situ morphologic, elemental and isotopic analysis of Archean life, In: Evolution of Archean Crust and Early Life. Modern Approaches in Solid Earth Sciences, Vol. 7: 351-365, 2015

cmca.uwa.edu.au 39

Journal Publications

1. J. Abduo, M. Bennamoun, M. Tennant and J. McGeachie, Effect of prosthodontic planning on intercuspal occlusal contacts: Comparison of digital and conventional planning, Computers in Biology and Medicine, 60: 132-150, 2015

2. J. Abduo, M. Bennamoun and M. Tennant, Influence of conventional and digital was-ups on axial tooth contour, International Journal of Petiodontics and Restorative Dentistry, 35(4): e50-59, 2015

3. J. Abduo, M. Bennamoun, M. Tennant and J. McGeachie, Effect of prosthodontic planning on lateral occlusion scheme: a comparison between conventional and digital planning, Journal of Applied Oral Science, 23(2): 196-205, 2015

4. J. Adbuo, Influence of fixed prosthodontic treatment on occlusal contacts in centric occlusion: A preliminary study, British Journal of Medicine and Medical Research, 5(12): 1580-1589, 2015

5. M. Alipoor, S.E. Maier, I.Y-H. Gu, A. Mehnert and F. Kahl, Optimal experiment design for monoexponential model fitting: Application to apparent diffusion coefficient imaging, BioMed Research International, 2015: 138060 (1-9), 2015

6. M. Alipoor, I.Y-H. Gu, A. Mehnert, S.E. Maier and G. Starck, K-optimal gradient encoding scheme for fourth-order tensor-based diffusion profile imaging, BioMed Research International, 760230 (1-10), 2015

7. M.D. Alotaibi, B.M. Patterson, A.J. Mckinley, A.Y. Reeder, A.J. Furness and M.J. Donn, Fate of benzotriazole and 5-methylbenzotriazole in recycled water recharged into an anaerobic aquifer: Column studies, Water Research, 70: 184-195, 2015

8. M.D. Alotaibi, B.M. Patterson, A.J. McKinley, A.Y. Reeder and A.J. Furness, Benzotriazole and 5-methylbenzotriazole in recycled water, surface water and dishwashing detergents from Perth, Western Australia: analytical method development and application, Environmental Science Processes & Impacts, 17: 448-457, 2015

9. M.D. Alotaibi, A.J. McKinley, B.M. Patterson and A.Y. Reeder, Benzotriazoles in the aquatic environment: A review of their occurrence, toxicity, degradation and analysis, Water Air and Soil Pollution, 226: 1-20, 2015

10. T.K. Ansell, P.K. McFawn, R.A. McLaughlin, D.D. Sampson, P.R. Eastwood, D.R. Hillman, H.W. Mitchell and P.B. Noble, Does smooth muscle in an intact airway undergo length adaptation during a sustained change in transmural pressure, Journal of Applied Physiology, 118: 533-543, 2015

11. P-I. Au, P. Clode, R.S.C. Smart and Y-K. Leong , Surface chemistry–microstructure–rheology of high and low crystallinity KGa-1b and KGa-2 kaolinite suspensions, Colloids and Surfaces A-Physicochemical and Engineering Aspects, 484: 354– 364, 2015

12. P-I. Au, B. Foo, Y-K. Leong, W.L. Zhang and H.J. Choi, Rheological analysis of graphene oxide coated anisotropic PMMA microsphere based electrorheological fluid from Couette flow geometry, Journal of Industrial and Engineering Chemistry, 21: 172-177, 2015

13. P-I. Au and Y-K. Leong, Fragmentation of polymer-bridged silica flocs by high shear impact: experiment and population balance modelling, Asia Pacific Journal of Chemical Engineering, 10 : 543-555, 2015

14. L. Avadiar, Y-K. Leong and A. Fourie, Physicochemical behaviors of kaolin slurries with and without cations—Contributions of alumina and silica sheets, Colloids and Surfaces A-Physicochemical and Engineering Aspects, 468: 103-113, 2015

15. T.S. Bailey, J.B. Bremner, B.W. Skelton and A.H. White, Synthesis and x-ray structural studies of a substituted 2,3,4,5-Tetrahydro-1H-3-benzazonine and a 1,2,3,5-Tetrahydro-4,3-benzoxazonine, Molecules, 20: 487-502, 2015

16. E.C. Barker, C.Y. Goh, F. Jones, M. Mocerino, B.W. Skelton, T. Becker and M.I. Ogden, Investigating hydrogel formation using in situ variable-temperature scanning probe microscopy, Chemical Science, 6: 6133-6138, 2015

17. E.A. Belousova, J.M.G. Jiménez, I.T. Graham, W.L. Griffin, S.Y. O’Reilly, N.J. Pearson, L.A.J. Martin, S. Craven and C. Talavera, The enigma of crustal zircons in upper-mantle rocks: Clues from the Tumut Ophiolite, Southeast Australia, Geology, 43(2): 119-122, 2015

18. S. Block, J. Ganne, L. Baratoux, Z. Zeh, L.A. Parra-Avila, M. Jessell, L. Ailleres and L. Siebenaller, Petrological and geochronological constraints on lower crust exhumation during Paleoproterozoic (Eburnean) orogeny, NW Ghana, West African Craton, Journal of Metamorphic Geology, 33: 463-494, 2015

19. B. Bohyman, G.R. Flematti and R.A. Barrow, Identification of hydroxymethylpyrazines using mass spectrometry, Journal of Mass Spectrometry, 50(8): 987-993, 2015

20. M.P. Boon, S. Freeman, M.I. Ogden, A. Oliveira, W.R. Richmond, B.W. Skelton and F. Jones, The many roles of mellitic acid during barium sulfate crystallization, Faraday Discussions, 179: 343-357, 2015


21. Y. Boyjoo, K. Merigot, J-F. Lamonier, V.K. Pareek, M.O. Tade and J. Liu, Synthesis of CaCO3@C yolk-shell particles for CO2 adsorption, RSC Advances, 5(32): 24872-24876, 2015

22. M. Bradshaw, T.D. Clemons, D. Ho, L. Gutierrez, F.J. Lazaro, M.J. House, T.G. St Pierre, M.W. Fear, F.M. Woods and K.S. Iyer, Manipulating directional cell motility using intracellular superparamagnetic nanoparticles, Nanoscale, 7(11): 4884-4889, 2015

23. M. Brasier, J. Antcliffe, M. Saunders and D. Wacey, Changing the picture of Earth’s earliest fossils (3.5-1.9 Ga) with new approaches and new discoveries, Proceedings of the National Academy of Sciences of the United States of America, 112(16): 4859-4864, 2015

24. M.I. Bruce, A. Burgun, J. George, B.K. Nicholson, C.R. Parker, B.W. Skelton, N. Scoleri, C.J. Sumby and N.N. Zaitseva, Some reactions of azides with diynyl-bis(phosphine) ruthenium-cyclopentadienyl complexes, Journal of Organometallic Chemistry, 797: 185-193, 2015

25. M.I. Bruce, M.L. Cole, B.G. Ellis, M. Gaudio, B.K. Nicholson, C.R. Parker, B.W. Skelton and A.H. White, The series of carbon-chain complexes {Ru(dppe)Cp∗}2{μ-(CC)x} (x = 4-8, 11): Synthesis, structures, properties and some reactions, Polyhedron, 86: 43-56, 2015

26. E.A. Buvaylo, V.N. Kokozay, R.P. Linnik, O.Yu. Vassilyeva and B.W. Skelton, Hybrid organic–inorganic chlorozincate and a molecular zinc complex involving the in situ formed imidazo[1,5-a]pyridinium cation: serendipitous oxidative cyclization, structures and photophysical properties, Dalton Transactions, 44: 13735-13744, 2015

27. E.A. Buvaylo, V.N. Kokozay, O.Yu. Vassilyeva, B.W. Skelton, M.M. Degtyarik, M. Korabik and J. Jezierska, Synthesis, structure, and characterizations of a new antiferromagnetic manganese(II) dichloro-bridged 1-D polymer decorated by 5-amino-1-H-tetrazole, Journal of Coordination Chemistry, 68(7): 1261-1272, 2015

28. E.A. Buvaylo, O.Yu. Vassilyeva and B.W. Skelton, Crystal structure of tetrakis(μ3-2-{[1,1-bis(hydroxymethyl)-2-oxidoethyl]iminomethyl}-6-methoxyphenolato) tetrakis[aquacopper(II)]: a redetermination at 200K, Acta Crystallographica Section E-Structure, E71: 1203-1206, 2015

29. E.A. Buvaylo, O.Yu. Vassilyeva and B.W. Skelton, Crystal structure of bis(2-{[1,1-bis(hydroxymethyl)-2-oxidoethyl]iminomethyl}-6-methoxyphenolato)-manganese(IV) 0.39-hydrate, Acta Crystallographica Section E. Chemical Communications, E71: 1307-1310, 2015

30. M. Challenor, R. O’Hare Doig, P. Fuller, M. Giacci, C. Bartlett, C.H. Wale, G.S. Cozens, L. Hool, S. Dunlop, K.S. Iyer, J. Rodger and M. Fitzgerald, Prolonged glutamate excitotoxicity increases GluR1 immunoreactivity but decreases mRNA of GluR1 and associated regulatory proteins in dissociated rat retinae in vitro, Biochimie, 112: 160-171, 2015

31. E.Y. Cheah, T.S. Mann, P.C. Burcham and P. Henry, Influenza A infection attenuates relaxation responses of mouse tracheal smooth muscle evoked by acrolein, Biochemical Pharmacology, 93: 519-526, 2015

32. K. Chen, J. Hyodo, A. Dodd, N. Ai, T. Ishihara, L. Jiane and S.P. Jiang, Chromium deposition and poisoning of La0.8Sr0.2MnO3 oxygen electrodes of solid oxide electrolysis cells, Faraday Discussions, 182: 457-476, 2015

33. K. Chen, S.S. Liu, P. Guagliardo, M.R. Kilburn, M. Koyama and S.P. Jiang, A fundamental study of boron deposition and poisoning of La0.8Sr0.2MnO3 cathode of solid oxide fuel cells under accelerated conditions, Journal of the Electrochemical Society, 162(12): F1282-1291, 2015

34. X. Chen and C.L. Raston, Liquid interface evolution of polyhedral-like graphene, Chemical Communications, 51(78): 14609-14612, 2015

35. Y. Cheng, C. Xu, L. Jia, J.D. Gale, L. Zhang, C. Liuc, P.K. Shen and S.P. Jiang, Pristine carbon nanotubes as non-metal electrocatalysts for oxygen evolution reaction of water splitting, Applied Catalysis B-Environmental, 163: 96-104, 2015

36. Y. Cheng, P.K. Shen, M. Saunders and S.P. Jiang, Core-shell structured PtRuCox nanoparticles on carbon nanotubes as highly active and durable electrocatalysts for direct methanol fuel cells, Electrochimica Acta, 177: 217-226, 2015

37. P.L. Clode, W.H. Koh and R.C.A. Thompson, Life without a host cell: What is cryptosporidium? Trends in Parasitology, 31(12): 614-624, 2015

38. P.L. Clode, A method for preparing difficult plant tissues for light and electron microscopy, Microscopy and Microanalysis, 21(4): 902-909, 2015

39. C. Cooper, P.L. Clode, D.P. Thomson and M. Stat, A flatworm from the Genus Waminoa (Acoela: Convolutidae) associated with bleached corals in Western Australia, Zoological Science, 32(5): 465-473, 2015

40. T. Coyle, H. Brumer and K.A. Stubbs, An improved preparation of some aryl a-L-arabinofuranosides for use as chromogenic substrates for L-alpha-L-arabinofuranosidases, Canadian Journal of Chemistry, 93(11): 1176-1180, 2015

41. D. D’Alessio, D.M. Lombardo, J.G. Vaughan, B.W. Skelton, K.R. Barnard and M.I. Ogden, Structural variations in metal complexes of a tertiary a-hydroxyoxime, Dalton Transactions, 44 (16): 7163-7168, 2015

42. D. D’Alessio, B.W. Skelton, N.A. Lengkeek, B.H. Fraser, A.M. Krause-Heuer, S. Muzzioli, S. Stagni, M. Massi and M.I. Ogden, Ionophoric properties of a tetra-tetrazole functionalised calix[4]arene, Supramolecular Chemistry, 27(11-12): 787-791, 2015

cmca.uwa.edu.au 41

43. A.W. Debowski, M. Sehnal, T. Liao, K.A. Stubbs, B.J. Marshall and M. Benghezal, Expansion of the tetracycline-dependent regulation toolbox for Helicobacter pylori, Applied and Environmental Microbiology, 81(23): 7969-7980, 2015

44. T.M. DeCarlo, G.A. Gaetani, M. Holcomb and A.L. Cohen, Experimental determination of factors controlling U/Ca of aragonite precipitated from seawater: Implications for interpreting coral skeleton, Geochimica et Cosmochimica Acta, 162: 151-165, 2015

45. B.F. Dessauvagie, C. Thomas, C. Robinson, F.A. Frost, J. Harvey and G.F. Sterrett, Validation of mitosis counting by automated phosphohistone H3 (PHH3) digital image analysis in a breast carcinoma tissue microarray, Pathology, 47(4): 329-334, 2015

46. M.G. Doyle, I.R. Fletcher, J. Foster, R.R. Large, R. Mathur, N.J. McNaughton, S. Meffre, J.R. Muhling, D. Phillips and B. Rasmussen, Geochronological constraints on the Tropicana Gold Deposit and Albany-Fraser Orogen, Western Australia, Economic Geology, 110: 355-386, 2015

47. S.G. Eaves, S.J. Hart, A.C. Whitwood, D.S. Yufit, P.J. Low and J.M. Lynam, Rapid Markovnikov addition of HCl to a pendant alkyne: evidence for a quinoidal cumulene, Chemical Communications, 51: 9362-9365, 2015

48. S.G. Eaves, D.S. Yufit, B.W. Skelton, J.A.K. Howard and P.J. Low, Syntheses, structural characterisation and electronic structures of some simple acyclic amino carbene complexes, Dalton Transactions, 44: 14341- 14348, 2015

49. S.G. Eaves, D.S. Yufit, B.W. Skelton, J.M. Lynam and P.J. Low, Reactions of alkynes with cis-RuCl2(dppm)2: exploring the interplay of vinylidene, alkynyl and η3-butenynyl complexes, Dalton Transactions, 44: 21016-21024, 2015

50. M.N. Gandy, C.L. Raston and K.A. Stubbs, Photoredox catalysis under shear using thin film vortex microfluidics, Chemical Communications, 51(55): 11041-11044, 2015

51. N.B. Edelman, T. Fritz, S. Nimpf, P. Pichler, M. Lauwers, R.W. Hickman, A. Papadaki-Anastasopoulou, L. Ushakova, T. Heuser, G.P. Resch, M. Saunders, J.A. Shaw and D.A.D. Keays, No evidence for intracellular magnetite in putative vertebrate magnetoreceptors identified by magnetic screening, Proceedings of the National Academy of Sciences of the United States of America, 112(1): 262-267, 2015

52. A. Ellis, R. Edwards, M. Saunders, R.K. Chakrabarty, R. Subramanian, A. van Riessen, A.M. Smith, D. Lambrinidis, L.J. Nunes, P. Vallelonga, I.D. Goodwin, A.D. Moy, M.A.J. Curran and T.D. van Ommen, Characterizing black carbon in rain and ice cores using coupled tangential flow filtration and transmission electron microscopy, Atmospheric Measurement Techniques, 8: 3959-3969, 2015

53. C.L. Elsegood, C.W. Chan, M.A. Degli-Esposti, M.E. Wikstrom, A. Domenichini, K. Lazarus, N. van Roojen, R. Ganss, J.K. Olynyk and G.C.T. Yeoh, Kupffer cell-monocyte communication is essential for initiating murine liver progenitor cell-mediated liver regeneration, Hepatology, 62(4): 1272-1284, 2015

54. S. Es’haghian, K. M. Kennedy, P. Gong, D.D. Sampson, R.A. McLaughlin and B.F. Kennedy, Optical palpation in vivo: imaging human skin lesions using mechanical contrast, Journal of Biomedical Optics, 20(1): art016013, 2015

55. E.O. Fridjonsson, S.J. Vogt, J.S. Vrouwenvelder and M.L. Johns, Early non-destructive biofouling detection in spiral wound RO membranes using a mobile earth’s field NMR, Journal of Membrane Science, 489: 227-236, 2015

56. Y.D. Friedland, T.F. Lee-Pullen, E. Nathan, R. Watts, J.A. Keelan, M.S. Payne and D.J. Ireland, Whole blood flow cytometric analysis of Ureaplasma-stimulated monocytes from pregnant women, Journal of Reproductive Immunology, 109: 84-88, 2015

57. R.O. Fuller, G.A. Koutsantonis, I. Lozić, M.I. Ogden and B.W. Skelton, Manganese-calcium clusters supported by calixarenes, Dalton Transactions, 44: 2132-2137, 2015

58. R.O. Fuller, C.S. Griffith, G.A. Koutsantonis, B.W. Skelton and A.H. White, Anion-directed solid-state structures of copper(I) and silver(I) adducts of ruthenium ethyne-1,2-diyl compounds, Organometallics, 34: 2632-2646, 2015

59. M.N. Gandy, L.T. Byrne and K.A. Stubbs, A simple and robust preparation of N-acetylindoxyls: Precursors for indigogenic substrates, Organic and Biomolecular Chemistry, 13(3): 905-908, 2015

60. T. Geisler, T.J. Nagel, M.R. Kilburn, A.C. Janssen, J.P. Icenhower, R.O.C. Fonseca, M.L. Grange and A.A. Nemchin, The mechanism of borosilicate glass corrosion revisited, Geochimica et Cosmochimica Acta, 158: 112-129, 2015

61. J.B.G. Gluyas, A.N. Sobolev, E.G. Moore and P.J. Low, Broad-band NIR transient absorption spectroscopy of an “all-carbon”-bridged bimetallic radical cation complex, Organometallics, 34: 3923-3926, 2015

62. J.B.G. Gluyas, V. Manici, S. Gückel, K.B. Vincent, D.S. Yufit, J.A.K. Howard, B.W. Skelton, A. Beeby, M. Kaupp and P.J. Low, Cross-conjugated systems based on an (E)Hexa-3-en-1,5-diyne-3,4-diyl skeleton: Spectroscopic and spectroelectrochemical investigations, Journal of Organic Chemistry, 80: 11501-11512, 2015


63. S.E. Grasby, B. Beauchamp, D.P.G. Bond, P. Wignall, C. Talavera, J.M. Galloway, K. Piepjohn, L. Reinhardt and D. Blomeier, Progressive environmental deterioration in northwestern Pangea leading to the latest Permian extinction, Geological Society of America Bulletin, 127(9-10): 1331-1347, 2015

64. N. Hardy, H.M. Viola, V.P. Johnstone, T.D. Clemons, H.C. Szappanos, R. Sing, N.M. Smith, K.S. Iyer and L.C. Hool, Nanoparticle-mediated dual delivery of an antioxidant and a peptide against the L-Type Ca2+ channel enables simultaneous reduction of cardiac ischemia-reperfusion injury, ACS NANO, 9(1): 279-289, 2015

65. C. Harris, P. le Roux, R. Cochrane, L. Martin, A.R. Duncan, J.S. Marsh, A.P. le Roex and C. Class, The oxygen isotope composition of Karoo and Etendeka picrites: High δ18O mantle or crustal contamination?, Contributions to Mineralogy and Petrology, 170(8): 1-24, 2015

66. N.T. Harvey, D.V. Spagnolo and B.A. Wood, “Could it be mycosis fungoides?”: an approach to diagnosing patch stage mycosis fungoides, Journal of Hematopathology, 8: 209-223, 2015

67. M. Hattie, T. Ito, A.W. Debowski, T. Arakawa, T. Katayama, K. Yamamoto, S. Fushinobu and K.A. Stubbs, Gaining insight into the catalysis by GH20 lacto-N-biosidase using small molecule inhibitors and structural analysis, Chemical Communications, 51(81): 15008-15011, 2015

68. H. He, Y. Kirilak, J. Kuo and H.G. Lambers, Accumulation and precipitation of magnesium, calcium, and sulfur in two Acacia (Leguminosae; Mimosoideae) species grown in different substrates proposed for mine-site rehabilitation, American Journal of Botany, 102(2): 290- 301, 2015

69. A-S. Hensler, S.G. Hagemann, C.A. Rosière, T. Angerer and S. Gilbert, Hydrothermal and metamorphic fluid-rock interaction associated with hypogene “hard” iron ore mineralisation in the Quadrilátero Ferrífero, Brazil: Implications from in-situ laser ablation ICP-MS iron oxide chemistry, Ore Geology Reviews, 69: 325-351, 2015

70. V.J. Hesler, B.W. Skelton, A.H. White, D.H. Brown and M.V. Baker, Calixarene/azolium cyclophane hybrids: synthesis, structure and conformations, Journal of Inclusion Phenomena and Macrocyclic Chemistry, 82: 53-69, 2015

71. V.J. Hesler, B.W. Skelton, A.H. White, D.H. Brown and M.V. Baker, Mercury complexes of an N-heterocyclic carbene derived from a calixarene/azolium cyclophane hybrid, Journal of Inclusion Phenomena and Macrocyclic Chemistry, 82: 71-78, 2015

72. D. Ho, J. Zou, X. Chen, A. Munshi, N.M. Smith, V. Agarwal, S.I. Hodgetts, G.W. Plant, A.J. Bakker, A.R. Harvey, I. Luzinov and K.S. Iyer, Hierarchical patterning of multifunctional conducting polymer nanoparticles as a bionic platform for topographic contact guidance, ACS NANO, 9(2): 1767-1774, 2015

73. J. Huang, L. Zhou, H. Wu, N. Pavlos, S.M. Chim, Q. Liu, J. Zhao, W. Xue, R.X. Tan, J. Ye, J. Xu, E.S. Ang, H. Feng, J. Tickner, J. Xu and Y. Ding, Triptolide inhibits osteoclast formation, bone resorption, RANKL-mediated NF-kappa B activation and titanium particle-induced osteolysis in a mouse model, Molecular and Cellular Endocrinology, 399: 346-353, 2015

74. D.J. Ireland, M.W. Kemp, Y. Miura, M. Saito, J.P. Newnham and J.A. Keelan, Intra-amniotic pharmacological blockade of inflammatory signalling pathways in an ovine chorioamnionitis model, Molecular Human Reproduction, 21(5): 479-489, 2015

75. N.M. Jaafar, P.L. Clode and L.K. Abbott, Soil microbial responses to biochars varying in particle size, surface and pore properties, Pedosphere, 25: 770-780, 2015

76. N.M. Jaafar, P.L. Clode and L.K. Abbott, Biochar-soil interactions in four agricultural soils, Pedosphere, 25: 729-936, 2015

77. K.D. Jones, J.E. Rixson, B.W. Skelton, K.M. Gericke and S.G. Stewart, The total synthesis of Heraclemycin B through β-Ketosulfoxide and aldehyde annulation, Asian Journal of Organic Chemistry, 4: 936-942, 2015

78. R. Jones, G.F. Ricardo and A.P. Negri, Effects of sediments on the reproductive cycle of corals, Marine Pollution Bulletin, 100: 13-33, 2015

79. C. Kaiser, M.R. Kilburn, P.L. Clode, L. Fuchslueger, M. Koranda, J.B. Cliff, Z.M. Solaiman and D.V. Murphy, Exploring the transfer of recent plant photosynthates to soil microbes: mycorrhizal pathway vs direct root exudation, New Phytologist, 205: 1537-1551, 2015

80. S.S. Kampmann, B.W. Skelton, D.A. Wild, G.A. Koutsantonis and S.G. Stewart, An air-stable nickel(0) phosphite precatalyst for primary alkylamine C–N cross-coupling reactions, European Journal of Organic Chemistry, 2015: 5995-6004, 2015

81. S.S. Kampmann, B.W. Skelton, G.C. Yeoh, L.J. Abraham, N.A. Lengkeek, K.A. Stubbs, C.H. Heath and S.G. Stewart, The synthesis and fluorescence profile of novel thalidomide analogues, Tetrahedron, 71: 8140-8149, 2015

82. S.S. Kampmann, B.W. Skelton, D.A. Wild, G.A. Koutsantonisa and S.G. Stewart, Tris(tri-o-tolyl phosphite-κP)nickel: a coordinatively unsaturated nickel(0) complex, Acta Crystallographica Section C. Structural Chemistry, C71: 188-190, 2015

83. S.S. Kampmann, N.Y.T. Man, A.J. McKinley, G.A. Koutsantonis and S.G. Stewart, Exploring the catalytic reactivity of nickel phosphine-phosphite complexes, Australian Journal of Chemistry, 68(12): 1842-1853, 2015

cmca.uwa.edu.au 43

84. F. Karimi, P.K. Pranzas, C. Pistidda, J.A. Puszkiel, C. Milanese, U. Vainio, M. Paskevicius, T. Emmler, A. Santoru, R. Utke, M. Tolkiehn, C.B. Minella, A.L. Chaudhary, S. Boerries, C.E. Buckley, S. Enzo, A. Schreyer, T. Klassen and M. Dornheim, Structural and kinetic investigation of the hydride composite Ca(BH4)2 + MgH2 system doped with NbF5 for solid-state hydrogen storage, Physical Chemistry Chemical Physics, 17(41): 27328-27342, 2015

85. J. Kekalainen, I. Larma, M. Linden and J.P. Evans, Lectin staining and flow cytometry reveals female-induced sperm acrosome reaction and surface carbohydrate reorganization, Scientific Reports, 5: Article Number: 15321, 2015

86. K.M. Kennedy, L. Chin, R.A. McLaughlin, B. Latham, C.M. Saunders, D.D. Sampson and B.F. Kennedy, Quantitative micro-elastography: imaging of tissue elasticity using compression optical coherence elastography, Scientific Reports, 5(15538): 1-12, 2015

87. B.F. Kennedy, R.A. McLaughlin, K.M. Kennedy, L. Chin, P. Wijesinghe, A. Curatolo, A. Tien, M. Ronald, B. Latham, C.M. Saunders and D.D. Sampson, Investigation of optical coherence micro-elastography as a method to visualize cancers in human breast tissue, Cancer Research, 75(16): 3236-3245, 2015

88. R.W. Kirk, B.F. Kennedy, D.D. Sampson and R.A. McLaughlin, Near video-rate optical coherence elastography by acceleration with a graphics processing unit, Journal of Lightwave Technology, 33(16): 3481-3485, 2015

89. J.L. Knipping, L.D. Bilenker, A.C. Simon, M. Reich, F. Barra, A.P. Deditius, M. Wӓlle, C.A. Heinrich, F. Holtz and R. Munizaga, Trace elements in magnetite from massive iron oxide-apatite deposits indicate a combined formation by igneous and magmatic-hydrothermal processes, Geochimica et Cosmochimica Acta, 171: 15- 38, 2015

90. J.L. Knipping, L.D. Bilenker, A.C. Simon, M. Reich, F. Barra, A.P. Deditius, C. Lundstrom, I. Bindeman and R. Munizaga, Giant Kiruna-type deposits form by efficient flotation of magmatic magnetite suspensions, Geology, 43(7): 591-594, 2015

91. L. Kotula, P.L. Clode, G.G. Striker, O. Pedersen, A. Lauchli, S. Shabala and T.D. Colmer, Oxygen deficiency and salinity affect cell-specific ion concentrations in adventitious roots of barley (Hordeum vulgare), New Phytologist, 208: 1114-1125, 2015

92. L. Kotula, H.A. Khan, J. Quealy, N.C. Turner, V. Vadez, K.H.M. Siddique, P.L. Clode and T.D. Colmer, Salt sensitivity in chickpea (Cicer arietinum L.): ions in reproductive tissues and yield components in contrasting genotypes, Plant Cell and Environment, 38: 1565-1577, 2015

93. S. Krishnan, E. Bakker, C. Lee, H.T. Kissick, D.J. Ireland and M.W. Beilharz, Successful combined intratumoral immunotherapy of established murine mesotheliomas requires B-cell involvement, Journal of Interferon & Cytokine Research, 35(2): 100-107, 2015

94. J. Kular, J.C. Tickner, N.J. Pavlos, H.M. Viola,T. Abel, B. Lim, X. Yang, H. Chen, R. Cook, L.C. Hool, M. Zheng and J. Xu, Choline kinase β mutant mice exhibit reduced phosphocholine, elevated osteoclast activity, and low bone mass, Journal of Biological Chemistry, 290(3): 1729-1742, 2015

95. W-J. Lee, G.A. Umana-Membreno, J. Dell and L. Faraone, Effect of CdS processing conditions on the properties of CdS/Si diodes and CdS/CdTe thin-film solar cells, IEEE Journal of Photovoltaics, 5(6): 1783-1790, 2015

96. W-J. Lee, J. Sharp, G.A. Umana-Membreno, J. Dell and L. Faraone, Investigation of crystallized germanium thin films and germanium/silicon heterojunction devices for optoelectronic applications, Materials Science in Semiconductor Processing, 30: 413-419, 2015

97. Y-K. Leong and B-C. Ong, Polyelectrolyte-mediated interparticle forces inaqueous suspensions: Molecular structure and surface forces relationship, Chemical Engineering Research and Design, 101: 44-55, 2015

98. C. Leslie, S.E. Bowyer, A. White, F. Grieu-Iacopetta, M. Trevenen, B. Iacopetta, B. Amanuel and M. Millward, FOXP3+ T regulatory lymphocytes in primary melanoma are associated with BRAF mutation but not with response to BRAF inhibitor, Pathology, 47(6): 557-563, 2015

99. G. Li, Q. Zheng, E. Landao-Bassonga, T.S. Cheng, N.J. Pavlos, Y. Ma, C. Zhang and M.H. Zheng, Influence of age and gender on microarchitecture and bone remodeling in subchondral bone of the osteoarthritic femoral head, Bone, 77: 91-97, 2015

100. X.P. Li, M. Roberts, Y.J. Liu, C.W. Kang, H. Huang and T.B. Sercombe, Effect of substrate temperature on the interface bond between support and substrate during selective laser melting of Al–Ni–Y–Co–La metallic glass, Materials and Design, 65: 1-6, 2015

101. X.P. Li, X.J. Wang, M. Saunders, A. Suvorova, L.C. Zhang, Y.J. Liu, M.H. Fang, Z.H. Huang and T.B. Sercombe, A selective laser melting and solution heat treatment refined Al–12Si alloy with a controllable ultrafine eutectic microstructure and 25% tensile ductility, Acta Materialia, 95: 74-82, 2015

102. C.B. Lim, C.M. Prêle, S. Baltic, P.G. Arthur, J. Creaney, D.N. Watkins, P.J. Thompson and S.E. Mutsaers, Mitochondria-derived reactive oxygen species drive GANT61-induced mesothelioma cell apoptosis, Oncotarget, 6(3): 1519-1530, 2015

103. I. Ling, A.N. Sobolev, K. Sabah and R. Hashim, Efficient packing of long flexible bis-imidazolium cations in the ubiquitous bilayers of their p-sulfonatocalixarene salts, CrystEngComm, 17(30): 5841-5848, 2015


104. I. Ling, A.N. Sobolev and C.L. Raston, Controlling the organization of phosphonium cations relative to p-sulfonatocalix[4]arene anions, CrystEngComm, 17(7): 1526-1530, 2015

105. Y.J. Liu, X.P. Li, L.C. Zhang and T.B. Sercombe, Processing and properties of topologically optimised biomedical Ti-24Nb-4Zr-8Sn scaffolds manufactured by selective laser melting, Materials Science and Engineering A- Structural Materials Properties Microstructure and Processing, 642: 268-278, 2015

106. H. Lu, P.K. Eggers, C.T. Gibson, X. Duan, R.N. Lamb, C.L. Raston and H.T. Chua, Facile synthesis of electrochemically active Pt nanoparticle decorated carbon nano onions, New Journal of Chemistry, 39(2): 915-920, 2015

107. H. Lu, W.S. Woi, X. Tan, C.T. Gibson, X. Chen, C.L. Raston, J.M. Gordon and H.T. Chua, Synthesis of few-layer graphene by lamp ablation, Carbon, 94: 349-351, 2015

108. H. Hui, K. Fuller, W.N. Erber and M.D. Linden, Measurement of monocyte-platelet aggregates by imaging flow cytometry, Cytometry Part A, 87A(3): 273-278, 2015

109. Y. Ma, M. Zhu, Z. Zhang and D. Zhang, Effect of a homogeneous combustion catalyst on the nanostructure and oxidative properties of soot from biodiesel combustion in a compression ignition engine, Proceedings of the Combustion Institute, 35: 1947-1954, 2015

110. Q. Mahmood, S. Li, A. Fhager, S. Candefjord, A. Chodorowski, A. Mehnert and M. Persson, A comparative study of automated segmentation methods for use in a microwave tomography system for imaging intracerebral haemorrhage in stroke patients, Journal of Electromagnetic Analysis and Applications, 7: 152-167, 2015

111. R.L. Marsh, R.B. Thornton, H.C. Smith-Vaughan, P. Richmond, S.J. Pizzutto and A.B. Chang, Detection of biofilm in bronchoalveolar lavage from children with non-cystic fibrosis bronchiectasis, Pediatric Pulmonology, 50: 284-292, 2015

112. S. Mazur, K. Turniak, J. Szczepański and N.J. McNaughton, Vestiges of Saxothuringian crust in the Central Sudetes, Bohemian Massif: Zircon evidence of a recycled subducted slab provenance, Gondwana Research, 27(2): 825-839, 2015

113. M.J. McCoy, C. Hemmings, T.J. Miller, S.J. Austin, M.K. Bulsara, N. Zeps, A.K. Nowak, R.A. Lake and C.F. Platell, Low strolam Foxp3+ regulatory T-cell density is associated with complete response to neoadjuvant chemoradiotherapy in rectal cancer, British Journal of Cancer, 113: 1677-1686, 2015

114. A.M. McDonnell, W.J. Lesterhuis, A. Khong, A.K. Nowak, R.A. Lake, A.J. Currie and B.W.S. Robinson, Tumor-infiltrating dendritic cells exhibit defective cross-presentation of tumor antigens, but is reversed by chemotherapy, European Journal of Immunology, 45(1): 49-59, 2015

115. M.J. McIldowie, B.W. Skelton, M. Mocerino and M.I. Ogden, A lanthanum picrate complex of a 1,2-bisamide substituted calix[4]arene, Journal of Inclusion Phenomena and Macrocyclic Chemistry, 82: 43-46, 2015

116. M.J. McIldowie, M. Mocerino, M.I. Ogden, B.W. Skelton and A.H. White, C4 Dissymmetric resorcinarene derivatives: synthesis, crystal structure and micelle formation, Journal of Inclusion Phenomena and Macrocyclic Chemistry, 82: 47-51, 2015

117. S. McLenachan, A.L. Magno, D. Ramos, J. Catita, P.G. McMenamin, F.K. Chen, E.P. Rakoczy and J. Ruberte, Angiography reveals novel features of the retinal vasculature in healthy and diabetic mice, Experimental Eye Research, 138: 6-21, 2015

118. K. Meitha, D. Konnerup, T.D. Colmer, J.A. Considine, C.H. Foyer and M.J. Considine, Spatio-temporal relief from hypoxia and production of reactive oxygen species during bud burst in grapevine (Vitis vinifera), Annals of Botany, 116(4): 703-711, 2015

119. P.J. Metaxas, M. Sushruth, R.A. Begley, J. Ding, R.C. Woodward, I.S. Maksymov, M. Albert, W. Wang, H. Fangohr, A.O. Adeyeye and M. Kostylev, Sensing magnetic nanoparticles using nano-confined ferromagnetic resonances in a magnonic crystal, Applied Physics Letters, 160(23): 232406 (1-5), 2015

120. J. Mo, P.K. Eggers, X. Chen, M.R.H. Ahamed, T. Becker, L.Y. Lim and C.L. Raston, Shear induced carboplatin binding within the cavity of a phospholipid mimic for increased anticancer efficacy, Scientific Reports, 5: 10414 (1-9), 2015

121. J. Moniodis, C.G. Jones, E.L. Barbour, J.A. Plummer, E.L. Ghisalberti and J. Bohlmann, The transcriptome of sesquiterpenoid biosynthesis in heartwood xylem of Western Australian sandalwood (Santalum spicatum), Phytochemistry, 113: 79- 86, 2015

122. P.R.T. Munro, A. Curatolo and D.D. Sampson, Full wave model of image formation in optical coherence tomography applicable to general samples, Optics Express, 23(3): 2541-2556, 2015

123. H.M. Nguyen, A.N. Rountree, J.J. Meeuwig, P.G. Coulson, M. Feng, S.J. Newman, A.M. Waite, C.B. Wakefield and M.G. Meekan, Growth of a deep-water predatory fish is influenced by the productivity of a boundary current system, Scientific Reports, 5: 9044, 2015

124. A.K. Nowak, A.M. Cook, A.M. McDonnell, M.J. Millward, J. Creaney, R.J. Francis, A. Hasani, A. Segal, A.W. Musk, B.A. Turlach, M.J. McCoy, B.W.S. Robinson and R.A. Lake, A phase 1b clinical trial of the CD40 activating antibody CP-870,893 in combination with cisplatin and pemetrexed in malignant pleural mesothelioma, Annals of Oncology, 26: 2488- 2490, 2015

125. E. O’Halloran, J. Kular, J. Xu, F. Wood and M. Fear, Non-severe burn injury leads to depletion of bone volume that can be ameliorated by inhibiting TNF- alpha, Burns, 41: 558-564, 2015

cmca.uwa.edu.au 45

126. J.J.L. Ong, A.N. Rountrey, J.J. Meeuwig, S.J. Newman, J. Zinke and M.G. Meekan, Contrasting environmental drivers of adult and juvenile growth in a marine fish: Implications for the effects of climate change, Scientific Reports, 5(10859): 1-11, 2015

127. M.C. Palmer, J.M. Scott, J.R. Muhling and A.K. Kennedy, Carboniferous metamorphism and partial melting of the Greenland Group in the Jackson River Valley, South Westland, New Zealand Journal of Geology and Geophysics, 58(1): 22-32, 2015

128. L.A. Parra-Avila, Y. Bourassa, J. Miller, S. Perrouty, M.L. Fiorentini and T.C. McCuaig, Age constraints of the Wassa and Benso mesothermal gold deposits, Ashanti Belt, Ghana, West Africa, Journal of African Earth Sciences, 112: 524-535, 2015

129. A.M. Passman, R.P. Strauss, S.B. McSpadden, M.L. Finch-Edmondson, K.H. Woo, L.A. Diepeveen, R. London, B.A. Callus and G.C. Yeoh, A modified choline-deficient, ethionine-supplemented diet reduces morbidity and retains a liver progenitor cell response in mice, Disease Models & Mechanisms, 8: 1635-1641, 2015

130. M.A. Pearce, A.J.R. White, L.A. Fisher, R.M. Hough and J.S. Cleverley, Gold deposition caused by carbonation of biotite during late-stage fluid flow, Lithos, 239: 114-127, 2015

131. Y. Peng, B. Baer-Imhoof, A.H. Millar and B. Baer, Consequences of Nosema apis infection for male honey bees and their fertility, Scientific Reports, 5: 10565 (1-11), 2015

132. V. Perumal, K. Krishnan, E. Gratton, A.M. Dharmarajan and S.A. Fox, Number and brightness analysis of sFRP4 domains in live cells demonstrates vesicle association signal of the NLD domain and dynamic intracellular responses to Wnt3a, International Journal of Biochemistry & Cell Biology, 64: 91-96, 2015

133. R. Pettinari, F. Marchetti, C. Pettinari, A. Petrini, B.W. Skelton, A.H. White, L. Bonfili, M. Cuccioloni and A.M. Eleuteri, Dinuclear (h6-arene) ruthenium(II) acylpyrazolone complexes: Synthesis, characterization and cytotoxicity, Journal of Organometallic Chemistry, 791: 1-5, 2015

134. V.M. Pinto, L.A. Hartmann, J.O.S. Santos and N.J. McNaughton, Zircon ages delimit the provenance of a sand extrudite from the Botucatu Formation in the Paraná volcanic province, Iraí, Brazil, Anais da Academia Brasileira de Ciências, 87(3): 1611-1622, 2015

135. N. Prakongkep, R.J. Gilkes and W. Wiriyakitnateekul, Forms and solubility of plant nutrient elements in tropical plant waste biochars, Journal of Plant Nutrition and Soil Science, 178: 732-740, 2015

136. S. Qin, E. Ang, L. Dai, X. Yang, D. Ye, H. Chen, L. Zhou, M. Yang, D. Teguh, R. Tan, J. Xu, J. Tickner, N.J. Pavlos and J. Xu, Natural germacrane sesquiterpenes inhibit osteoclast formation, bone resorption, RANKL-Induced NF-kappa B activation, and I kappa B alpha degradation, International Journal of Molecular Sciences, 16(11): 26599-26607, 2015

137. V.A. Ramos, M. Escayola, P. Leal, M.M. Pimentel and J.O.S. Santos, The late stages of the Pampean Orogeny, Córdoba (Argentina): Evidence of postcollisional Early Cambrian slab break-off magmatism, Journal of South American Earth Sciences, 64(2): 351-364, 2015

138. B. Rasmussen, B. Krapež, J.R. Muhling and A. Suvorova, Precipitation of iron silicate nanoparticles in early Precambrian oceans marks Earth’s first iron age, Geology, 43(4): 303-306, 2015

139. B. Rasmussen, B. Krapež and J.R. Muhling, Seafloor silicification and hardground development during deposition of 2.5 Ga banded iron formations, Geology, 43(3): 235-238, 2015

140. S. Rea, A. Stevenson, N.L. Giles, F.M. Wood and M.W. Fear, Cells from the hematopoietic lineage are only present transiently during healing in a mouse model of non-severe burn injury, Stem Cell Research & Therapy, 6: 134, 2015

141. B.L. Reid, S. Stagni, J.M. Malicka, M. Cocchi, A.N. Sobolev, B.W. Skelton, E.G. Moore, G.S. Hanan, M.I. Ogden and M. Massi, Lanthanoid/alkali metal β-Triketonate assemblies: A robust platform for efficient NIR emitters, Chemistry-A European Journal, 21: 18354-18363, 2015

142. B.L. Reid, E.G. Moore, B.W. Skelton, M.I. Ogden and M. Massi, Investigation of the photophysical properties of a Eu3+ coordination polymer bearing an a-nitrile substituted b-diketonate ligand via emission and ultrafast transient absorption spectroscopy, Australian Journal of Chemistry, 68: 1392-1398, 2015

143. J. Reisser, B. Slat, K. Noble, K. du Plessis, M. Epp, M. Proietti, J. de Sonneville, T. Becker and C. Pattiaratchi, The vertical distribution of buoyant plastics at sea: an observational study in the North Atlantic Gyre, Biogeosciences, 12: 1249-1256, 2015

144. Y. Ribeiro, R.C. Figueiredo e Silva, L.M. Lobato, L.C. Lima, F.J. Ríos, S.G. Hagemann and J.B. Cliff, Fluid inclusion and sulfur and oxygen isotope studies on quartz-carbonate-sulfide veins of the Carvoaria Velha deposit, Córrego do Sítio gold lineament, Quadrilátero Ferrífero, Minas Gerais, Brazil, Ore Geology Reviews, 67: 11-33, 2015

145. G.F. Ricardo, R.J. Jones, P.L. Clode, A. Humanes and A.P. Negri, Suspended sediments limit coral sperm availability, Scientific Reports, 5: 18084, 2015

146. T.W. Ritchie, J.M. Scott, J.R. Muhling and A.K. Kennedy, Cretaceous metamorphism, magmatism and shearing in the Waipuna Valley, directly south of the Reefton Goldfield, New Zealand Journal of Geology and Geophysics, 58(2): 89-103, 2015


147. J.E. Rixson, J.R. Abraham, Y. Egoshi, B.W. Skelton, K. Young, J. Gilbert, J.A. Sakoff, K.M. Gericke, A. McCluskey and S.G. Stewart, The synthesis and biological activity of novel anthracenone-pyranones and anthracenone-furans, Bioorganic & Medicinal Chemistry, 23: 3552-3565, 2015

148. C.L. Ross, J.L. Falter, V. Schoepf and M.T. McCulloch, Perennial growth of hermatypic corals at Rottnest Island, Western Australia (32°S), PeerJ, DOI 10.7717/peerj.781: 1-25, 2015

149. S. Rubanov, B.A. Fairchild, A. Suvorova, P. Olivero and S. Prawer, Structural transformation of implanted diamond layers during high temperature annealing, Nuclear Instruments and Methods in Physics Research B, 365: 50-54, 2015

150. I.W. Sadwika, K. Feindel, S.I. Hodgetts, S. Bunt, A. Wittek and K. Millar, MRI protocols comparison of in-vivo spinal cord imaging of the rats for segmentation purposes, International Journal of Research in Science, 1(3): 1-4, 2015

151. W. Salama, A. El-Kammar, M. Saunders, R. Morsy and C. Kong, Microbial pathways and palaeoenvironmental conditions involved in the formation of phosphorite grains, Safaga District, Egypt, Sedimentary Geology, 325: 41-58, 2015

152. S.N. Samarin, O.M. Artamonov, P.R. Guagliardo, L. Praviça, A.P. Baraban, F.O. Schümann and J.F. Williams, Emission of correlated electron pairs from Au(111) and Cu(111) surfaces under low-energy electron impact: Contribution of surface states, d-states and spin effects, Journal of Electron Spectroscopy and Related Phenomena, 198: 26-30, 2015

153. S.N. Samarin, O.M. Artamonov, A.P. Baraban, M. Kostylev, P. Guagliardo and J.F. Williams, Controlling spin–orbit interaction in a ferromagnetic Fe/Au double layer, Applied Physics Letters, 106: 042404 (1-4), 2015

154. S.N. Samarin, O.M. Artamonov, A.P. Baraban, M. Kostylev, P. Guagliardo and J.F. Williams, Excitation of plasmons in Ag/Fe/W structure by spin-polarized electrons, Applied Physics Letters, 107: 101602 (1-5), 2015

155. P.A. Schauer, B.W. Skelton and G.A. Koutsantonis, Coordinating tectons 4: coordination chemistry of the 4,5-diazafluoren-9-yl moiety as a metallo-ligand for allenylidene complexes, Organometallics, 34: 4975-4988, 2015

156. M. Schmieder, E. Tohver, F. Jourdan, S.W. Denyszyn and P.W. Haines, Zircons from the Acraman impact melt rock (South Australia): Shock metamorphism, U–Pb and 40Ar/39Ar systematics, and implications for the isotopic dating of impact events, Geochimica et Cosmochimica Acta, 161: 71-100, 2015

157. M. Schmieder, H.C. Aoudjehane, E. Buchner and E. Tohver, Meteorite traces on a shatter cone surface from the Agoudal impact site, Morocco, Geological Magazine, 152(4): 751-757, 2015

158. T.H. Schneider, M. Rieger, K. Ansorg, A.N. Sobolev, T. Schirmeister, B. Engels and S. Grabowsky, Vinyl sulfone building blocks in covalently reversible reactions with thiols, New Journal of Chemistry, 39: 5841-5853, 2015

159. E. Scibiorskia, E. Tohvera and F. Jourdan, Rapid cooling and exhumation in the western part of the Mesoproterozoic Albany-Fraser Orogen, Western Australia, Precambrian Research, 265: 232-248, 2015

160. L. Scolaro, D. Lorenser, W-J. Madore, R.W. Kirk, A.S. Kramer, G.C. Yeoh, N. Godbout, D.D. Sampson, C. Boudoux and R.A. McLaughlin, Molecular imaging needles: Dual-modality optical coherence tomography and fluorescence imaging of labeled antibodies deep in tissue, Biomedical Optics Express, 6(5): 1767-1781, 2015

161. J.M. Scott, A. Auer, J.R. Muhling, T.A. Czertowicz, A.F. Cooper, M.A. Billa and A.K. Kennedy, New P-T and U-Pb constraints on Alpine Schist metamorphism in south Westland, New Zealand, New Zealand Journal of Geology and Geophysics, 58(4): 385-397, 2015

162. T.B. Sercombe, X. Xu, V.J. Challis, R. Green, S. Yue, Z. Zhang and P.D. Lee, Failure modes in high strength and stiffness to weight scaffolds produced by Selective Laser Melting, Materials and Design, 67: 501-508, 2015

163. S. Shamsi, Y. Chen and L.Y. Lim, Characterization and biological properties of NanoCUR formulation and its effect on major human cytochrome P450 enzymes, International Journal of Pharmaceutics, 495(1): 194-203, 2015

164. J. Shaw, A. Boyd, M. House, R. Woodward, F. Mathes, G. Cowin, M. Saunders and B. Baer, Magnetic particle-mediated magnetoreception, Journal of The Royal Society Interface, 12: 20150499 (1-15), 2015

165. M.W. Shi, S.P. Thomas, G.A. Koutsantonis and M.A. Spackman, Supramolecular recognition and energy frameworks in host-guest complexes of 18-crown-6 and sulfonamides, Crystal Growth & Design, 15: 5892-5900, 2015

166. A.Y. Sim, K.E. Wallman, T.J. Fairchild and K.J. Guelfi, Effect of high-intensity intermittent exercise training on appetite regulation, Medicine and Science in Sports and Exercise, 47(11): 2441-2449, 2015

167. P.V. Simpson, D.H. Brown, B.W. Skelton, A.H. White and M.V. Baker, Palladium complexes of o-xylylene-linked alkoxybenzimidazolin- 2-ylidenes containing aryl N-substituents: examples of C–H activation and the formation of a tri-nuclear palladium complex, Journal of Inclusion Phenomena and Macrocyclic Chemistry, 82: 79-91, 2015

cmca.uwa.edu.au 47

168. R.H. Smithies, C.L. Kirkland, J.B. Cliff, H.M. Howard and R. Quentin de Gromard, Syn-volcanic cannibalisation of juvenile felsic crust: Superimposed giant 18O-depleted rhyolite systems in the hot and thinned crust of Mesoproterozoic central Australia, Earth and Planetary Science Letters, 424: 15-25, 2015

169. H.J. Spero, S.M. Eggins, A.D. Russell, L. Vetter, M.R. Kilburn and B. Hönisch, Timing and mechanism for intratest Mg/Ca variability in a living planktic foraminifer, Earth and Planetary Science Letters, 409: 32-42, 2015

170. Z. Sun, S. Shi, X. Hu, X. Guo, J. Chen and H. Chen, Short-aramid-fiber toughening of epoxy adhesive joint between carbon fiber composites and metal substrates with different surface morphology, Composites Part B-Engineering, 77: 38-45, 2015

171. X. Sun, A. Keating and G. Parish, Stress control of porous silicon films for microelectromechanical systems, Microporous and Mesoporous Materials, 208: 88-94, 2015

172. Z. Sun, S. Shi, X. Hu, H. Chen and Z. Wong, Adhesive joints between carbon fiber and aluminum foam reinforced by surface-treated aramid fibers, Polymer Composites, 2015: 192-197, 2015

173. M.T. Sweetapple and S. Tassios, Laser-induced breakdown spectroscopy (LIBS) as a tool for in situ mapping and textural interpretation of lithium in pegmatite minerals, American Mineralogist, 100(10): 2141-2151, 2015

174. Y.M. Syah and E.L. Ghisalberti, Flavanone derivatives from Macaranga tanarius, Biochemical Systematics and Ecology, 62: 151-154, 2015

175. N.K. Tangudu, V.K. Verma, T.D. Clemons, S.S. Beevi, T. Hay, G. Mahidhara, M. Raja, R.A. Nair, L.E. Alexander, A.B. Patel, J. Jose, N.M. Smith, B. Zdyrko, A. Bourdoncle, I. Luzinov, K.S. Iyer, A.R. Clarke, and L.D. Kumar, RNA interference using c-Myc–Conjugated nanoparticles suppresses breast and colorectal cancer models, Molecular Cancer Therapeutics, 14(5): 1259-1269, 2015

176. P.A. Thompson, P. Bonham, P. Thomson, W. Rochester, M.A. Doblin, A.M. Waite, A. Richardson and C.S. Rousseaux, Climate variability drives plankton community composition changes: the 2010–2011 El Niňo to La Niňa transition around Australia, Journal of Plankton Research, 37(5): 966-984, 2015

177. V.K. Truong, D.E. Mainwaring, P. Murugaraj and D.H.K. Nguyen and E.P. Ivanova, Impact of confining 3-D polymer networks on dynamics of bacterial ingress and self-organisation, Journal of Materials Chemistry B, 3: 8704-8710, 2015

178. M.B. Uloth, M.P. You and M.J. Barbetti, Host resistance to sclerotinia stem rot in historic and current Brassica napus and B. juncea varieties: critical management implication, Crop & Pasture Science, 66: 841-848, 2015

179. M.B. Uloth, P.L. Clode, M.P. You and M.J. Barbetti, Calcium oxalate crystals: An integral component of the Sclerotinia sclerotiorum/Brassica carinata pathosystem, PLoS One, 10(3): p.e0122362, 2015

180. K.M. Usher, A.H. Kaksonen, D. Bouquet, K.Y. Cheng, Y. Geste, P.G. Chapman and C.D. Johnston, The role of bacterial communities and carbon dioxide on the corrosion of steel, Corrosion Science, 98: 354-365, 2015

181. S.M. Valvis, J. Waithman, F.M. Wood, M.W. Fear and V.S. Fear, The immune response to skin trauma Is dependent on the etiology of injury in a mouse model of burn and excision, Journal of Investigative Dermatology, 135(8): 2119-2128, 2015

182. M.J. Van Kranendonk, C.L. Kirkland and J. Cliff, Oxygen isotopes in Pilbara Craton zircons support a global increase in crustal recycling at 3.2Ga, Lithos, 228-229: 90-98, 2015

183. N. Vielreicher, D. Groves, N. McNaughton and I. Fletcher, The timing of gold mineralization across the eastern Yilgarn craton using U–Pb geochronology of hydrothermal phosphate minerals, Mineralium Deposita, 50: 391-428, 2015

184. F. Voute and N. Thebaud, Structural, mineralogical and geochemical constraints on the atypical komatiite-hosted Turret deposit in the Agnew–Mt. White District, Western Australia, Mineralium Deposita, 50: 697-716, 2015

185. D. Wacey, M.R. Kilburn, M. Saunders, J.B. Cliff, C. Kong, A.G. Liu, J.J. Matthews and M.D. Brasier, Uncovering framboidal pyrite biogenecity using nano-scale CNorg mapping, Geology, 43(1): 27-30, 2015

186. D. Wacey, N. Noffke, J.B. Cliff, M.E. Barley and J. Farquhar, Micro-scale quadruple sulfur isotope analysis of pyrite from the ~3480Ma Dresser Formation: New insights into sulfur cycling on the early Earth, Precambrian Research, 258: 24-35, 2015

187. M.H. Wahid, U.H. Stroeher, E. Eroglu, X. Chen, K. Vimalanathan, C.L. Raston and R.A. Boulos, Aqueous based synthesis of antimicrobial-decorated graphene, Journal of Colloid and Interface Science, 443: 88-96, 2015

188. M.C. Walkey, L. Byrne, M.J. Piggott, P.J. Low and G.A. Koutsantonis, Enhanced bi-stability in a ruthenium alkynyl spiropyran complex, Dalton Transactions, 44: 8812-88, 2015

189. T. Wang, Q. Liu, L. Zhou, J.B. Yuan, X. Lin, R. Zeng, X. Liang, J. Zhao and J. Xu, Andrographolide inhibits ovariectomy-induced bone loss via the suppression of RANKL signaling pathways, International Journal of Molecular Sciences, 16(11): 27470-27481, 2015

190. A.Y. Wang, Y. Shen, L.J. Liew, J.T. Wang, M. von Unge, M.D. Atlas and R.J. Dilley, Searching for a rat model of chronic tympanic membrane perforation: healing delayed by mitomycin C/dexamethasone but not paper implantation or iterative myringotomy, International Journal of Pediatric Otorhinolaryngology, 79: 1240-1247, 2015

191. R. Wei, H. Yang and D. Zhang, Synthesis of inter-crystalline mesoporous ZSM-5 generated by self-interlocked MFI nanosheet stacks, RSC Advances, 5(78): 63765-63776, 2015


192. M.V. Werrett, G.S. Huff, S. Muzzioli, V. Fiorini, S. Zacchini, B.W. Skelton, A. Maggiore, J.M. Malicka, M. Cocchi, K.C. Gordon, S. Stagni and M. Massi, Methylated Re(I) tetrazolato complexes: photophysical properties and light emitting devices, Dalton Transactions, 44: 8379-8393, 2015

193. M.V. Werrett, P.J. Wright, P.V. Simpson, P. Raiteri, B.W. Skelton, S. Stagni, A.G. Buckley, P.J. Rigby and M. Massi, Rhenium tetrazolato complexes coordinated to thioalkyl-functionalised phenanthroline ligands: Synthesis, photophysical characterisation, and incubation in live HeLa cells, Dalton Transactions, 44: 20636-20647, 2015

194. D.T. Wijeratne, J. Rodger, H.J. Wallace, S. Maghami, M. Sykes, F.M. Wood and M.W. Fear, Ephrin-A2 and Ephrin-5 are important for the functional development of cutaneous innervation in a mouse model, Journal of Investigative Dermatology, 135: 632-635, 2015

195. P. Wijesinghe, R.A. McLaughlin, D.D. Sampson and B.F. Kennedy, Parametric imaging of viscoelasticity using optical coherence elastography, Physics in Medicine and Biology, 60: 2293-2307, 2015

196. J-P. Wu, M. Walton, A. Wang, P. Anderson, T. Wang, T.B. Kirk and M.H. Zheng, The development of confocal arthroscopy as optical histology for rotator cuff tendinopathy, Journal of Microscopy, 259(3): 269-275, 2015

197. W. Wu, Z. Wan, W. Chen, M. Zhu and D. Zhang, Synthesis of mesoporous alumina with tunable structural properties, Microporous and Mesoporous Materials, 217: 12-20, 2015

198. Q. Xiong, W.L. Griffin, JP. Zheng, S.Y. O’Reilly and N.J. Pearson, Episodic refertilization and metasomatism of Archean mantle: evidence from an orogenic peridotite in North Qaidam (NE Tibet, China), Contributions to Mineralogy and Petrology, 169(31): 1-24, 2015

199. J-Z. Yang, X-Z. Hu, R. Sultana, R.E. Day and P. Ichim, Structure design and manufacturing of layered bioceramic scaffolds for load-bearing bone reconstruction, Biomedical Materials, 10: 045006 (1-10), 2015

200. R. Yang, Y. Elankumaran, N. Hijjawi and U. Ryan, Validation of cell-free culture using scanning electron microscopy (SEM) and gene expression studies, Experimental Parasitology, 153: 55-62, 2015

201. J. Yang, F. Meng, X. Xu, P.T. Robinson, Y.D. Dilek, A.B. Makeyev, R. Wirth, M. Wiedenbeck and J.B. Cliff, Diamonds, native elements and metal alloys from chromitites of the Ray-Iz ophiolite of the Polar Urals, Gondwana Research, 27: 459-485, 2015

202. W. Yuan, Y. Cheng, P.K. Shen, C.M. Li and S.P. Jiang, Significance of wall number on the carbon nanotube support-promoted electrocatalytic activity of Pt NPs towards methanol/formic acid oxidation reactions in direct alcohol fuel cells, Journal of Materials Chemistry A, 3(5): 1961-1971, 2015

203. E.O. Zappettini, B. Coira, J.O.S. Santos, C.E. Cisterna and E. Belousova, Combined U-Pb and Lu-Hf isotope study from the Las Lozas volcanics, northwestern Argentina: evidence of juvenile Cryogenian-derived, lower Pennsylvanian volcanism in Western Gondwana, Journal of South American Earth Sciences, 59: 13-18, 2015

204. G. Zemunik , B.L. Turner, H. Lambers and E. Laliberté, Diversity of plant nutrient-acquisition strategies increases during long-term ecosystem development, Nature Plants, Article number: 15050: (1-4), 2015

205. J. Zhang, S. Lu, Y. Xiang, P.K. Shen, J. Liu and S.P. Jiang, Carbon-nanotubes-supported Pd nanoparticles for alcohol oxidations in fuel cells: Effect of number of nanotube walls on activity, CHEMSUSCHEM, 8(17): 2956- 2966, 2015

206. L. Zhao, Y. Cheng and S.P. Jiang, A new, high electrochemical activity and chromium tolerant cathode for solid oxide fuel cells, International Journal of Hydrogen Energy, 40: 15622-15631, 2015

207. L. Zhou, F. Song, Q. Liu, M. Yang, J. Zhao, R. Tan, J. Xu, G. Zhang, J.M.W. Quinn, J. Tickner and J. Xu, Berberine sulfate attenuates osteoclast differentiation through RANKL induced NF-kappa B and NFAT pathways, International Journal of Molecular Sciences, 16(11): 27087-27096, 2015

208. J-W. Zia, B. Rasmussen, J.R. Muhling, I.R. Fletcher, A.M. Thorne, S.P. Johnson, H.N. Cutten, D.J. Dunkley and F.J. Korhonen, In situ U–Pb geochronology of xenotime and monazite from the Abrapolymetallic deposit in the Capricorn Orogen, Australia: Dating hydrothermal mineralization and fluid flow in a long-lived crustal structure, Precambrian Research, 260: 91-112, 2015

cmca.uwa.edu.au 49

C. K. Hagen, P. R. T. Munro, M. Endrizzi, P. C. Diemoz and A. Olivo Scitation, Low-dose phase contrast tomography with conventional x-ray sources, The International Journal of Medical Physics Research and Practice, 41: 7, 2014.

E. Paynter, B. Baer-Imhoof, M. Linden, T. Lee-Pullen, K. Heel, P. Rigby and B. Baer, Flow Cytometry as a Rapid and Reliable Method to Quantify Sperm Viability in the Honeybee Apis mellifera, Cytometry 85A: 5, 2014.

W. Koh, A. Thompson, H. Edwards, P. Monis, and P. L Clode. Extracellular excystation and development of Cryptosporidium: tracing the fate of oocysts within Pseudomonas aquatic biofilm systems. BMC Microbiology 2014, 14:281 doi:10.1186/s12866-014-0281-8.

M.T. Hill and M. C. Gather, Advances in small lasers. Nature Photonics Landscape of nanophotonics 8(12): 908-918, 2014.

Journal covers 2014

X. Chen, N.M. Smith, K. Swaminathan Iyer, and C.L. Raston. Controlling nanomaterial synthesis, chemical reactions and self assembly in dynamic thin films. Chem Soc Rev 43 (5), March 2014.

V. Agarwal, E. S. Tjandra, K. S. Iyer, B. Humfrey, M. Fear, F. M. Wood, S. Dunlop and C. L. Raston, Evaluating the effects of nacre on human skin and scar cells in culture. Toxicology Research 3 (4), July 2014.


D. D’Alessio, D.M. Lombardo, J. G. Vaughan, B.W. Skelton, K.R. Barnard and M. Ogden. Structrual variations in metal complexes of a tertiary a-hydroxyoxime. Dalton Transactions 44(16) April 2015.

Journal covers 2015

P.L. Clode, A method for preparing difficult plant tissues for light and electron microscopy. Microscopy and Microanalysis 21 (4) August 2015.

P.L. Clode, W.H. Koh, R.C.A. Thompson. Life without a Host Cell: What is Cryptosporidium? Trends in Parasitology 31 (12) December 2015.

cmca.uwa.edu.au 51

Centre for Microscopy, Characterisation and Analysis

The University of Western AustraliaM010, Perth WA 6009 AustraliaTel: +61 8 6488 2770Email: [email protected]

CRICOS Provider Code: 00126G UniPrint 135213

Centre for Microscopy,Characterisation and Analysis

annual report · 2017-04-03 · engaging with australia’s eresearch and informatics community,...

Documents