animal lab research pros and cons
TRANSCRIPT
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8/16/2019 Animal Lab Research Pros and Cons
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PROS CONS
Allow researchers to study a test subject for a whole life
span
Humans can live up to 80 years or more, which means some
scientists would be dead before others results will be gathered.
Laboratory mice, on the other hand, only live for 2 to 3 years,
giving researchers an opportunity to study effects of genetic
manipulation or treatments over an entire lifetime. In some
cases, they can continue to study across several generations.
his is why mice and rats have been used for long!term canceresearch.
Cruel and inhumane treatment
"rotocols in animal testing are often painful to the test sub#e
hey are forced fed, deprived of food and water, restrained
physically for prolonged periods, inflicted with burns, wound
and pain to test for healing process effects and remedies, a
even $illed through nec$!brea$ing or asphy%iation. his is
according to the Humane &ociety International. 'hen testin
evaluate irritation caused by cosmetics, for e%ample, a rabb
eyes will be held open by clips so it cannot blin$ away the
products being evaluated. he clips usually stay on for days
and to ensure the rabbits stay in place, they are incapacitate
&ome e%perimentation also involves using lethal doses of
certain chemicals to determine how much can $ill animals.
Humans and animals are almost identical in many ways
he )*+ of chimpanees are -- similar with humans, while
he genetics of mice are -8 similar. Humans and animals are
also biologically similar, having the same set of organs,
bloodstream and central nervous system, which is why they are
affected with the same diseases and health conditions. /iven
hese circumstances, animals used in e%perimentation do serveas appropriate research sub#ects.
Animals make poor test subjects
his statement is a direct contradiction from what proponen
believe about how closely related animals and humans are
anatomically and biologically, because of the many metabol
cellular, and anatomical differences between the two specie
sing rats for to%icity, for e%ample, must not be accepted as
reliable since humans are nowhere close to being 10!$ilogra
rats, according to homas Hartung, professor of evidence!bto%icology at ohns Hop$ins niversity. his is further suppo
by the 203 study in the +rchives of o%icology that states th
the lac$ of direct comparison of human data versus that of a
mouse ma$es the usefulness of research data dubious.
Provides adeuate livin!" whole body system test subject
*o other living thing in this planet has the closest anatomical
structure as humans than animals. + human body is e%tremely
comple% that cell cultures in a petri dish cannot provide
sufficient test results or proof that a cure or product is effective.
esting a drug for side effects, for e%ample, re4uires a
circulatory system that will carry the drug to different organs.&tudying interrelated processes is also best done in sub#ects
with endocrine system, immune system, and central nervous
system, something humans and animals have. 'hat about the
use of computer models5 hey would re4uire accurate
nformation that is gathered from animal research.
Success in animal e#perimentation does not euate to
human safety
'hen the sleeping pill thalidomide was tested on pregnant r
mice, cats and guinea pigs, there were no incidence of birth
defects, e%cept when administered at e%tremely high doses
However, when it was used by pregnant women, it resulted severe deformities affecting 0,000 babies.
• he arthritis drug 6io%%, which turned out great on
animals was really bad news on humans because it cau
more than 20,000 heart attac$s and sudden cardiac dea
• + ma#ority of the drugs that passed animal tests, -7
be e%act, failed in human clinical trials.
• 00 of the drugs designed to treat stro$e wor$ed on
animals, but completely failed in humans
• ver 89 vaccines for HI6 wor$ed well in primates, b
failed in humans
Can lead to misleadin! research
&ome medicines and products that are harmful to animals a
actually valuable to humans. +spirin, for e%ample, was almo
shelved because it proved dangerous for animals. Imagine w
would have happened if aspirin was completely ta$en off the
pharmaceutical list5 here would have been no way to lowe
ris$ of organ transplant being re#ected.
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Animals are protected from abuse and mistreatment
:ontrary to what most opponents believe, animal research is
highly regulated, with laws enacted to protect animals. &ince
-;;, the federal +nimal 'elfare +ct have been regulating
animal e%perimentation.
I+::? that will approve all proposals to
use animals for e%perimentation.
he I+:: will be responsible for enforcing humane treatment
of animals.
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are wasting plenty of government dollars allocated for
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)ewer animals are used in research than as food for
humans
:ompared to the amount of chic$en, cattle, sheep and pigs that
humans eat, relatively few of them are used in e%perimentation.
'ith consideration to the medical progress and advancement
such tests provided, it is a small price to pay. o illustrate, for
every chic$en used in research, an e4uivalent of 370 are used
as food.
Plenty of animal lives are wasted
:onsidering all the tests that failed, not to mention other non
e%perimental factors that affect animals, there is a significan
number of animal lives wasted for nothing. hey suffer or ge
$illed during the e%periment, and suffer the same fate after t
e%periment. @ut what is really inhumane and unethical are t
poor research procedures used by some facilities. &erious f
were discovered in plenty of studies in the E and the .&.
use rodents, according to a peer!reviewed study conducted
200-. &election bias was a ma#or problem, but even with
randomiation and blinding techni4ue used, proper selection
animals still failed. here is also a lac$ of hypothesis or ob#e
related to the study.
Contributes to many cures and treatments that save many
human lives
he ma#ority of the medical brea$throughs that have happened
n the last 00 years were direct results from animal research
and e%perimentation, according to the :alifornia @iomedical