anatomia sist dig

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    Digestive System Anatomy

    Digestive tract Alimentary tract or

    canal

    GI tract

    Accessory organs Primarily glands

    Regions Mouth or oral cavity

    Pharynx

    Esophagus Stomach

    Small intestine

    Large intestine

    Anus

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    Digestive System Regulation

    Nervous regulation

    Involves enteric nervous

    system

    Types of neurons: sensory,motor, interneurons

    Coordinates peristalsis

    and regulates local

    reflexes

    Chemical regulation

    Production of hormones

    Gastrin, secretin Production of paracrine

    chemicals

    Histamine

    Help local reflexes in ENS

    control digestive

    environments as pH levels

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    Oral Cavity

    Mouth or oral cavity Vestibule: Space

    between lips or cheeksand alveolar processes

    Oral cavity proper

    Lips (labia) and

    cheeks

    Palate: Oral cavityroof Hard and soft

    Palatine tonsils Tongue: Involved in

    speech, taste,mastication,swallowing

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    Teeth

    Two sets

    Primary, deciduous,

    milk: Childhood

    Permanent orsecondary: Adult (32)

    Types

    Incisors, canine,

    premolar and molars

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    Tooth structure:

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    Salivary Glands

    Produce saliva Prevents bacterial

    infection

    Lubrication

    Contains salivaryamylase

    Breaks down starch

    Three pairs

    Parotid: Largest

    Submandibular

    Sublingual: Smallest

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    Pharynx and Esophagus

    Pharynx

    Nasopharynx

    Oropharynx: Transmitsfood normally

    Laryngopharynx:

    Transmits food

    normally

    Esophagus Transports food from

    pharynx to stomach

    Passes through esophageal

    hiatus (opening) ofdiaphragm and ends atstomach Hiatal hernia

    Sphincters

    Upper Lower

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    Deglutition (Swallowing)

    Three phasesVoluntary

    Bolus of food moved by tongue from oral cavity topharynx

    Pharyngeal

    Reflex: Upper esophageal sphincter relaxes, elevatedpharynx opens the esophagus, food pushed intoesophagus

    Esophageal Reflex: Epiglottis is tipped posteriorly, larynx elevated

    to prevent food from passing into larynx

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    Phases of Deglutition

    (Swallowing)

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    Stomach Anatomy:

    Openings

    Gastroesophageal:

    To esophagus

    Pyloric: To

    duodenum

    Regions

    Cardia

    Fundus

    Body

    Pylor

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    Stomach Histology:

    Layers Serosa or visceral

    peritoneum:

    Outermost

    Muscularis: Threelayers

    Outer longitudinal

    Middle circular

    Inner oblique

    Submucosa

    Mucosa

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    Phases of Gastric

    Secretion

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    Movements in Stomach

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    Small Intestine

    Site of greatest amount ofdigestion and absorption

    Divisions Duodenum

    Jejunum

    Ileum: Peyers patches orlymph nodules

    Modifications Circular folds or plicae

    circulares, villi, lacteal,

    microvilli Cells of mucosa

    Absorptive, goblet, granular,endocrine

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    Small Intestine Secretions

    Mucus Protects against digestive enzymes and stomach acids

    Digestive enzymes

    Disaccharidases: Break down disaccharides tomonosaccharides

    Peptidases: Hydrolyze peptide bonds

    Nucleases: Break down nucleic acids

    Duodenal glands Stimulated by vagus nerve, secretin, chemical or tactile

    irritation of duodenal mucosa

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    Duodenum and Pancreas

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    Liver

    Lobes Major: Left and right

    Minor: Caudate and

    quadrate

    Ducts Common hepatic

    Cystic

    From gallbladder

    Common bile

    Joins pancreatic duct at

    hepatopancreatic ampulla

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    Functions of the Liver

    Bile production Salts emulsify fats, contain pigments as bilirubin

    Storage Glycogen, fat, vitamins, copper and iron

    Nutrient interconversion

    Detoxification Hepatocytes remove ammonia and convert to urea

    Phagocytosis Kupffer cells phagocytize worn-out and dying red and white blood cells,

    some bacteria

    Synthesis Albumins, fibrinogen, globulins, heparin, clotting factors

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    Duct System

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    Gallbladder

    Bile is stored and concentrated

    Stimulated by cholecystokinin and vegal

    stimulation

    Dumps into small intestine

    Production of gallstones possible

    Drastic dieting with rapid weight loss

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    Pancreas

    Anatomy

    Endocrine

    Pancreatic islets produce

    insulin and glucagon

    Exocrine

    Acini produce digestive

    enzymes

    Regions: Head, body, tail

    Secretions

    Pancreatic juice (exocrine) Trypsin

    Chymotrypsin

    Carboxypeptidase Pancreatic amylase

    Pancreatic lipases

    Enzymes that reduce DNAand ribonucleic acid

    L I i

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    Large Intestine:

    Extends from ileocecal junction to anus

    Consists of cecum, colon, rectum, anal canal

    Movements sluggish (18-24 hours)

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    Large Intestine

    Cecum Blind sac, vermiform appendix attached

    Colon Ascending, transverse, descending, sigmoid

    Rectum Straight muscular tube

    Anal canal Internal anal sphincter (smooth muscle) External anal sphincter (skeletal muscle)

    Hemorrhoids: Vein enlargement or inflammation

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    Movement in Large Intestine

    Mass movements Common after meals

    Local reflexes in enteric plexus Gastrocolic: Initiated by stomach

    Duodenocolic: Initiated by duodenum

    Defecation reflex Distension of the rectal wall by feces

    Defecation Usually accompanied by voluntary movements to expel feces

    through abdominal cavity pressure caused by inspiration

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    Digestion Absorption

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    Digestion, Absorption,

    Transport

    Digestion

    Breakdown of food molecules for absorption into

    circulation

    Mechanical: Breaks large food particles to small

    Chemical: Breaking of covalent bonds by digestive

    enzymes

    Absorption and transport Molecules are moved out of digestive tract and into

    circulation for distribution throughout body

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    Functions of the Liver

    Bile production Salts emulsify fats, contain pigments as bilirubin

    Storage Glycogen, fat, vitamins, copper and iron

    Nutrient interconversion

    Detoxification Hepatocytes remove ammonia and convert to urea

    Phagocytosis Kupffer cells phagocytize worn-out and dying red and white blood cells,

    some bacteria

    Synthesis Albumins, fibrinogen, globulins, heparin, clotting factors

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    Lipoproteins

    Types

    Chylomicrons

    Enter lymph

    VLDL LDL

    Transports cholesterol

    to cells

    HDL Transports cholesterol

    from cells to liver

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    W d I

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    Water and Ions:

    Water Can move in either direction

    across wall of small intestine

    depending on osmotic

    gradients

    Ions

    Sodium, potassium, calcium,

    magnesium, phosphate are

    actively transported

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