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Sample & Assay Technologies ADNAGenotyp0909S1WW Rely on trusted automated and manual workflow solutions for: Sample collection and stabilization Genomic DNA purification, DNA storage, and whole genome amplification PCR amplification and automated QIAxcel ® fragment analysis HRM ® and Pyrosequencing ® detection Making improvements in life possible — www.qiagen.com Genotyping sample and assay technologies by QIAGEN Analyzing genetic differences

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Page 1: Analyzing genetic differences · 2010-01-22 · Restriction Enzymes from New England Biolabs With 35 years of experience in enzyme technology, New England Biolabs leads the industry

Sample & Assay Technologies

AD

NA

Gen

oty

p0

909S1W

W

Rely on trusted automated and manual workflow solutions for:

Sample collection and stabilization■

Genomic DNA purification, DNA storage, and whole genome amplification■

PCR amplification and automated QIAxcel■ ® fragment analysis

HRM■ ® and Pyrosequencing® detection

Making improvements in life possible — www.qiagen.com

Genotyping sample and assay technologies by QIAGEN

Analyzing genetic differences

Page 2: Analyzing genetic differences · 2010-01-22 · Restriction Enzymes from New England Biolabs With 35 years of experience in enzyme technology, New England Biolabs leads the industry

AAAS, Publisher of Science

presents the sponsors and supporters of the

2010 Annual MeetingBridging Science and Society

18—22 February • San Diego

AAAS wishes to thank our sponsors and supporters:

Presenting Sponsor

In addition generous funding for AAAS Awards is provided by the Kavli Foundation and Affymetrix.

Be part of a proven equation:Your Organization + AAAS Annual Meeting = Global Visibility

Call today about the bene�ts of sponsorships currently available:

Jill C. PerlaAAAS MeetingsDirect Dial: (202) 326-6736E-mail: [email protected]

Page 3: Analyzing genetic differences · 2010-01-22 · Restriction Enzymes from New England Biolabs With 35 years of experience in enzyme technology, New England Biolabs leads the industry

GE HealthcareLife Sciences

ÄKTA, Amersham, Biacore and Whatman are trademarks of GE Healthcare companies.© 2009 General Electric Company – All rights reserved.First published September 2009GE Healthcare Bio-Sciences AB, Björkgatan 30, 751 84 Uppsala, Sweden

GE12-09

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and investment in the future that being part of GE can bring.

Want to know more? Why not talk with us today. Visit www.gelifesciences.com/aktaavant

I ÄKTA I Amersham I Biacore I IN Cell Analyzer I Whatman I GE Service I

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Page 4: Analyzing genetic differences · 2010-01-22 · Restriction Enzymes from New England Biolabs With 35 years of experience in enzyme technology, New England Biolabs leads the industry

© 2009 Life Technologies Corporation. All rights reserved. For Research Use Only. Not for use in diagnostic procedures.

Trademarks of Life Technologies Corporation and its affiliated companies: AB Logo™, Applied Biosystems®. TaqMan is a registered trademark of Roche Molecular Systems, Inc.All other trademarks are the sole property of their respective owners. Products are covered by IP rights held by and licensed from Olink AB, Sweden.

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Page 5: Analyzing genetic differences · 2010-01-22 · Restriction Enzymes from New England Biolabs With 35 years of experience in enzyme technology, New England Biolabs leads the industry

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Page 6: Analyzing genetic differences · 2010-01-22 · Restriction Enzymes from New England Biolabs With 35 years of experience in enzyme technology, New England Biolabs leads the industry

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Page 7: Analyzing genetic differences · 2010-01-22 · Restriction Enzymes from New England Biolabs With 35 years of experience in enzyme technology, New England Biolabs leads the industry

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Build new scientific relationships andexplore the best way to conduct a clinicaland translational science career at CTSciNet,the new online community from Science,Science Careers, and AAAS made possibleby the Burroughs Wellcome Fund.

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In 2010, theCouncil for theAdvancementof ScienceWritingwill observe its50th anniversary.

Since its founding, CASW has worked toimprove the public’s understanding andappreciation of science and technology byconducting programs designed to enhancethe quality of science and medical reporting and by fostering strongerrelationships between scientists and the media.

We’d like to hear from you about CASW’s impact.

To help commemorate our half-century milestone, the CASW boardinvites comments, observations and reminiscences from any and allwho have participated in our programs, including:

■ Scientists, reporters, writers and science writing educators who have presentedat, covered or attended CASW’s annual New Horizons in Science® brie�ngs forscience writers;

■ Public affairs of�cers of academic institutions that have hosted the 47 NewHorizons brie�ngs held to date;

■ Recipients of CASW traveling and academic fellowships;

■ Recipients of CASW science writing “residencies” at leading research institutions;

■ Writers and editors who participated in CASW’s “traveling guru” program (aimedat improving local coverage of science) and “brown bag” initiative (designed toenlighten scientists about the practice of science journalism).

■ Donors who have helped make our programs possible.

We’re eager to hear from all. Please visit our Website, www.casw.org,and click on 50 Years of Science and Science Writing to tell us whatCASW’s efforts have meant to the science community and the publicand how we can best continue to serve over the next 50 years.

CASW•P.O.Box910,Hedgesville,WV•304.754.6786•www.casw.org

Help UsCelebrate

Page 8: Analyzing genetic differences · 2010-01-22 · Restriction Enzymes from New England Biolabs With 35 years of experience in enzyme technology, New England Biolabs leads the industry

Dalia Abdel-SalamOctavio Aburto-OropezaArun AgrawalPeter C. AgreOlanrewaju AinaA. Hadi Al KhaliliBruce M. AlbertsJonathan AlgerLuca AlinoviBrad AllenbyAbdalla AlnajjarDavid AndersonRichard AskeyLloyd AxworthyStefan BachuPeter BackusJeffrey BadaMaureen A. BaginskiChunli BaiBarbara A. BairdDavid BaltonChristopher BartyGeorge BasileDavid BaulcombeJulia BaumRichard D. BegerFrances BeineckeKeith BellPhilip BellArden L. BementEshel Ben-JacobKennette BenedictMark L. BenthienAndrea BertozziBernard BigotLinda BillingsChristine A. BironRichard BissellPratim BiswasRobert Biswas-DienerCecilia BitzErich BlochSally BlowerRay BoemanSteve BogradWilliam BondJacques BouchardJean-Phillipe Bouchaud

Philip BourneW. Thomas BoyceMaxwell T. BoykoffAlan BoyleShannon BradleySteven J. BramsLewis M. BranscombJohn BransfordJames BraseJames BrewerWilliam B. BridgesLarry BrilliantEdward BriscoeLars BromleyDaniel G. BrownMarilyn BrownPeter BrunsHarvey BryanJed Z. BuchwaldJames BuizerMartin BunzlDennis R. BurtonJohn BwarieRobert L. ByerKen CaldeiraMeg CaldwellTyrone CannonLon R. CardonLynda T. CarlsonSebastian CarneyMark CarrMichael CarrSean M. CarrollJean-Laurent CasanovaGail CassellKenneth CassmanThomas CastenCarlos Castillo-ChavezClaudia CeveniniOliver ChadwickChristopher ChambersFrances ChampagneGrantley D. CharlesR. Alta CharoHongda ChenZhong ChenDonghong ChengSo-Min CheongKevin Chipman

Patrick ChristieSarah P. ChuRatana ChuenpagdeeYoon ChungJoshua E. CinnerConstance CitroKC ClaffyAndrew ClarkChristopher ClarkDouglas ClarkElizabeth ClarksonKathryn ClayBeatriz C. ClewellKenneth CoaleTheo ColbornArthur L. ColemanE. William ColglazierBrianno CollerScott L. CollinsVicki ColvinRita R. ColwellSusan G. ConardCassie ConleyTara ConnellyPamela G. ConradWilliam C. CopelandMarie CoppolaClemencia CosentinoChristopher CostelloDonna CoxPeter CraneRobert P. CreaseLarry CrowderIan CruteYi CuiLisa M. CurranCynthia CwikBruce DaleGeorge DaleyAl DarzinsPeter DaszakJon Michael DavisAndre de GouveaJose Antonio de la PeñaMaryellen de MarsMichele de NigrisJulio de PaulaGerda de VriesPierre Degond

Richard DeMilloNancy DenslowKemal DervisKeith DevlinRoseanne DiabMariette DiChristinaCatherine DidionEd DienerGeorge DimopoulosCarl DjerassiWalter Doer�erCheng DonghongSimon DonnerFanny DouvereFrank D. DrakeJohn W. DrakeAnna DreberKelvin DroegemeierSean DrummondCatherine DulacKevin N. DunbarGreg J. DuncanMaitreya DunhamWilliam DunlopMike DunneJim DunwellJoachim EblePaul H. EdelmanRobert EdwardsScott EdwardsBud EhlerCharles N. EhlerHajo EickenNadia El-AwadyLynn E. ElfnerKirsten EllenbogenJohn EllisMichael EmermanKaren EmmoreyRobert EngleSaskia Estupiñán-DayE. Margaret EvansVictoria J. FabryJames FahnJ. Doyne FarmerRichard A. FeelyNina FeffermanSuzanne E. FentonLuigi Ferrucci

Phillip FinckDiane FischerMartin FisherRichard FlavellJames R. FlemingLamont FlowersJo FodenJames FowlerMarye Anne FoxMichelle FoxHarrison S. FrakerRobert T. FraleyCatherine FrancheUta FranckeMarcos FrankAndrew G. FraserKimberley FreemanWilliam R. FreudenburgUwe FritscheMonique FrizeBruce A. FuchsErin M. FurtakAbraham GademuFred H. GageMichele Gar�nkelS. James GatesJohn GearhartJames Paul GeePallab GhoshPeter J. GianarosHolly K. GibbsJohn GillelandKristina GjerdeMalti GoelStig GoetheEdward J. GoetzlSimon GoldbardMadge GoldmanLawrence GoldsteinVladimir GolitsynPatrick GonzalesFederico GoodsaidDmitry A. GordeninStephen GrandRobert GrantGiorgio GrattaLou GrayHenry GreelyStanley Gregory

Carol W. GreiderTina Grieco-CalubMelinda GrierHuw Grif�thsKirsten Grorud-ColvertTony H. GrubesicSeth GuikemaLauren GundersonDavid H. GustonEvan HadinghamVictoria HaleAmy Laura HallCharles HallJason Hall-SpencerChristopher G. HallidayBenjamin HalpernDiane F. HalpernLarry A. HammondMarah J. HardtTracy HartMohamed H.A. HassanEgill HaukssonRobert M. HazenBob HebnerJeff HechtJames HeckmanRichard HeinbergDirk HelbingJohn F. HelliwellAndrea HendersonSocrates HerreraAlejandro HerreroLawrence A. HerzogMark HildebrandAmy HillJohn HocevarKeith HodgsonJules A. HoffmannMarika M. HollandHugo HollandersPhilip J. HolmesGreg HorowitPaul HorowitzSteve HortonPaul HorwitzDerek HoustonKenneth HuberTerry HughesArti Hurria

AAAS, publisher of Science, presents

Nearly 700 speakers whowill convene in San DiegoWho do you know? Who do youwant tomeet?

Page 9: Analyzing genetic differences · 2010-01-22 · Restriction Enzymes from New England Biolabs With 35 years of experience in enzyme technology, New England Biolabs leads the industry

Register now: www.aaas.org/meetings

Jo HusbandsIan D. HutcheonSusanne IhsenIoannis IkessidesBarbara IllmanIrwin JacobsJennifer JacquetRudolf JaenischDavid JentschChris JohnsonJean JohnsonKristina JohnsonLucile M. JonesThomas H. JordanCliff JoslynGerald F. JoyceTina KaarsbergKathryn KailikoleJim KakaliosDan KammenCarrie KappelDavid KeithJamie Lewis KeithWillett KemptonDiane KetelhutSuk Joon KimLonnie KingNicole KingDavid KlahrGeorge KleinJoanie KleypasErik KlopferMichael KlymkowskyMarcelo KnobelLeon KochianKaren KohfeldKasper KokRichard D. KolodnerMaria KozhevnikovNina KrausMeg A. KrawchukTim KringMichael LässigMyanna LahsenSherman LaiDolores J. LambZeph LandauEric S. LanderJulia LaneNeal LaneDaniel J. LangChris LangdonTom LaughlinLester LaveStephan LechnerJune Seung LeeWim LeemansVladimir LefebvreAnthony LeggettJack R. LeibowitzSarah E. LesterTeresa LettieriBruce V. LewensteinNathan LewisRebecca LewisonTim Ley

XiaoChun LiBarbara LibbyMike LindstromMarcia LinnBjörn-Ola LinnérAndy LipkisChris Llewellyn-SmithDavid LobellKathryn LongChristopher G. LoweStefano LuccioliStephen LuoniKlaus LutzenkirchenJonathan LynchJohn LynhamSonja LyubomirskyPatricia L. MabryAllison MacfarlaneAnne Jane MacLachlanFrancis MacrinaKatherine MagnusonNatalie MahowaldArunava MajumdarShirley M. MalcomBradley MalinStanley MaloyGeoffrey ManleyMargaret MannChristopher ManningLori MarinoElizabeth MarshallDaniel MartellLaura MartinJoan Martinez-AlierKrzysztof MaruszewskiWieslaw MaslowskiWalter E. MasseyIvan MaticAndrew D. MaynardSarah McCaffreyWilliam McClintockKathleen McDermottBruce S. McEwenMark McGranaghanAmy McGuireMarcia McNuttSara C. MednickJulia E. MelkersDennis MeredithFrederick L. MerrillStephen A. MerrillVera MichalchikEdward L. MilesJon D. MillerMeredith MinklerErik Jap MolenaarMegan MollenhauerSuresh MoolgavkarJames L. MooreAlejandro MorenoGranger MorganJohn MortonEdward MosesMehdi MoussaidRongping MuSead Muftic

Daniel R. MuhsMargaret MurnaneJason MurrayCharles C. MuscoplatSteven MusserLynn NadelHiroshi NaganoYuko NaganoRosamond NaylorJeff NesbitClaudia NeuhauserRobert NichollsMary D. NicholsPeter NicholsonH.E. Tsuneo NishidaHendrik H. NollensDoug NowacekRuth Nowjack-RaymerArthur J. NozakRon O’DorMichael O’HareOnche OdehJay OdellShigehiro OishiCarol OliverStephen G. OliverDonald W. OlsonLennart OlssonNaomi OreskesElinor OstromDorcas OtienoJennifer OuelletteBernhard O. PalssonStephen R. PalumbiBecky ParkerJohn ParmentolaRon PateAniruddh D. PatelHeather B. PatisaulAri PatrinosTad PatzekTanya T. PaullDaniel PaulyDavid N. PayneIvette PerfectoSidney PerkowitzDonald K. PerovichTed PetersKeith PezzoliJulia PhillipsWilliam D. PhillipsSteward T.A. PickettEllen K. PikitchStewart L. PimmHuang PingRichard PlevinGeoffrey S. PlumleeRichard PollnacWendy PollockShirley PomponiKeith PorterOscar PorterJeffrey P. PrestemonJules PrettyKenneth PrewittHuw Price

Patti PriceSusanna PriestLuisa PristaJoseph M. ProsperoMargaret RaceMichael Ra�iLee RainieBaldev RajRegina RameikaJohn S. RamsdellPhilip J. RaschAndrew RassweilerDavid H. RauletGerrit RauwsStephen RavertyCatherine RedgwellDaniel C. ReedKnut ReinertDiana ReissMary RellingFelix RemboldOrtwin RennCurt RiceLiesl RiddleDavid RidlingJohn RobinsonDan RodenOscar RomoMargot RooseveltJo Ellen RosemanAndrew RosenbergSusan M. RosenbergCynthia RosenzweigIvor RoystonCarol RubinEdward S. RubinMary RuckelshausNorah RudinRosaura RuizJohn RummelIvan RusynDonald G. SaariJames SallisWayne SamuelsonJames N. SanchiricoCarmen SapienzaHiram SarabiaDaniel SarewitzCarter SavageAkira SawaAnna Lee SaxenianDaniel L. SchacterHarry N. ScheiberRoland SchenkelGottfried SchlaugStephen H. SchneiderSylvia Schwaag SergerKellogg SchwabLori SchwackeBrian SchwartzMegan SchwarzmanEugenie C. ScottRichard SearsEdward SeidelRobert SemperIsmail Serageldin

Juliet P. ShafferJohn SheehanJohn ShepherdKinya ShimizuThomas F. ShipleyOlive ShishanaPaul ShuchRajesh ShuklaAnthony SiegmanEllen V. SigalBrian SillimanJacob SilvermanFinbarr SloaneLarry SmarrBrian SmithDouglas SmithHarold SmithLaurel Smith-DoerrV. Scott SolbergRobert SolowRalf SommerfeldKevin St. MartinH. Eugene StanleyMelanie StegmanJeff SteinDirk SteinkeAdin SteinsaltzJane StevensMartin StorskdieckSteffanie StrathdeeThomas W. SwetnamToshiki TajimaKazuhiko TakeuchiHeather TallisPaul TanenbaumMargaret TaylorVolker ter MeulenSharon TerryClaes ThegerströmDavid TilmanGeorge E. TitaEwen C. ToddGeorge TolleyJasna TomicThomas P. TomichEric J. TopolAline TribolletLoucas TsakalakosMary TurnipseedJohn TysonChristina UlleniusDavid UlphHans G. UlrichVishal S. VaidyaWilliam J. ValdezAndre Van SteirteghemJohn G. VandenberghHal R. VarianJay VavraEnriqueta VelardeStephanie Venn-WatsonCraig VenterJames VerdinJoseph M. VinetzRobert C. von BorstelTomoaki Wada

Graham C. WalkerMatthew WalkerJohn WalshFenyu WangPatsy Wang-IversonMasataka WatanabeAlice WatersLes WatlingMichelle WattFrank WattenbergRaoul WeilerMartin WeissScott WeissIrving WeissmanDavid W. WellerKevin D. WellsDan WerthimerJohn WettlauferMaurice WhelanAlan WhiteCrow WhiteThomas I. WhiteLyndell WhitleyNorm WhittonDouglas J. WiebeArnim WiekHarry WilandPeter A. WildererBrian WilliamsDavid R. WilliamsFiona WilliamsJennifer M. WilsonRichard WilsonCynthia WinstonOwen WitteNathan WolfeSusan Wol�nbargerGordon WooJohn WoodNanette WoontonBoris WormDavid WrightJohn WrightWilliam WulfVictor YakovenkoDaniel YankelovichMasaru YarimeKimberley YatesBanhar YeapGary YoheJeong-Ro YoonChristina YoungStanley YoungStephen YoungerDihua YuLauren ZeiseDadi ZhouS. Lawrence ZipurskyBora ZivkovicMyrsini ZorbaRamunas Zydelis

2010 AAAS Annual Meeting18-22 February—San Diego

Start connecting nowwww.aaas.org/meetings

Page 10: Analyzing genetic differences · 2010-01-22 · Restriction Enzymes from New England Biolabs With 35 years of experience in enzyme technology, New England Biolabs leads the industry

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Page 11: Analyzing genetic differences · 2010-01-22 · Restriction Enzymes from New England Biolabs With 35 years of experience in enzyme technology, New England Biolabs leads the industry

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Under the Patronage ofHis Majesty King Abdullah II of Jordan

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Bringing the latest discoveries in basic, clinical, and translational

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March 7-10, 2010King Hussein

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Dead Sea, Jordan

Page 12: Analyzing genetic differences · 2010-01-22 · Restriction Enzymes from New England Biolabs With 35 years of experience in enzyme technology, New England Biolabs leads the industry
Page 13: Analyzing genetic differences · 2010-01-22 · Restriction Enzymes from New England Biolabs With 35 years of experience in enzyme technology, New England Biolabs leads the industry

Since 1848, AAAS has served as a prominent voice to advance science and as a valuable

resource for scientists, educators, and policy makers. For the past 100 years, part of

this mission has included publishing the journal Science, one of the world’s premier

peer-reviewed research journals. Working together to disseminate the most compelling

discoveries across all scientific disciplines, AAAS and Science continue to fulfill their

mission of advancing science for the benefit of all.

In addition to supporting Science, individual memberships are a driving force behind

critical AAAS programs and activities designed to strengthen the global scientific

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allowing AAAS to continue its mission of advancing science and serving society, but you

also gain powerful resources to develop your own career.

As a member, you’ll receive 51 issues of the journal Science delivered weekly as well

as online access to: groundbreaking research before it’s published; the Science online

archives dating back to 1880; and the current table of contents. In addition to all the

benefits provided by the journal Science, AAAS has partnered on behalf of its members

to provide substantial discounts with numerous organizations, including: Apple, VISA,

GEICO, Barnes & Noble, and more.

If you’re interested in becoming a AAASmember and changing the face of science, please

visit aaas.org. Join us. Together we can make a difference.

Page 14: Analyzing genetic differences · 2010-01-22 · Restriction Enzymes from New England Biolabs With 35 years of experience in enzyme technology, New England Biolabs leads the industry

A country devastated by genocide and a crippling AIDS epidemic. Together with the Rwandan Ministry of Education,

AAAS, the world’s largest multidisciplinary scientific society and publisher of Science magazine, is working to ensure

that local children gain skills in science, technology, math, and engineering. And this is just one of the ways that

AAAS is committed to advancing science to support a healthy and prosperous

world. Join us. Together we can make a difference. aaas.org/plusyou/rwanda

Rwanda

Page 15: Analyzing genetic differences · 2010-01-22 · Restriction Enzymes from New England Biolabs With 35 years of experience in enzyme technology, New England Biolabs leads the industry

In America today, 1 in 3 individuals does not accept evolution.1 That’s why AAAS continues to play an important

role in the effort to protect the integrity of science education. AAAS is hard at work ensuring that evolution

continues to be taught in science classrooms, but we need your help.

Join us. Together we can make a difference. aaas.org/plusyou/evolution

Evolution

1. Pew Research Center for the People & the Press. May 2009, General Public Science Survey.

Page 16: Analyzing genetic differences · 2010-01-22 · Restriction Enzymes from New England Biolabs With 35 years of experience in enzyme technology, New England Biolabs leads the industry

Historically Black Colleges and Universities (HBCUs) increase the number of underrepresented ethnic

minorities qualified for education and research in science, technology, engineering, and mathematics

(STEM). AAAS partners with NSF to host a national gathering that highlights undergraduate student

research to enhance the quality of STEM education. And this is just one of the ways that AAAS is committed

to advancing science to support a healthy and prosperous world.

Join us. Together we can make a difference. aaas.org/plusyou/hbcuup

HBCU-UP NationalResearch Conference

Page 17: Analyzing genetic differences · 2010-01-22 · Restriction Enzymes from New England Biolabs With 35 years of experience in enzyme technology, New England Biolabs leads the industry

To meet the challenge of the competitive economy in the new millennium, private industry and

government research agencies must expand the pool of technical talent. AAAS started Entry

Point!, a program that offers students with disabilities competitive internship opportunities

in science, engineering, mathematics, computer science, and some fields of business.

And this is just one of the ways that AAAS is committed to advancing science to support a

healthy and prosperous world. Join us. Together we

can make a difference. aaas.org/plusyou/entrypoint

Entry Point!Students with Disabilities

Page 18: Analyzing genetic differences · 2010-01-22 · Restriction Enzymes from New England Biolabs With 35 years of experience in enzyme technology, New England Biolabs leads the industry

Remote, isolated, catastrophic events occur across the globe that affect civilians, the

environment, indigenous rights, and more. The AAAS Science and Human Rights Program

uses geospatial technologies to broaden the ability of non-governmental organizations

to rapidly gather, analyze, and disseminate information in these times of crisis. And

this is just one of the ways that AAAS is committed to advancing science to support

a healthy and prosperous world. Join us. Together we

can make a difference. aaas.org/plusyou/humanrights

Geospatial TechnologiesHuman Rights

Page 19: Analyzing genetic differences · 2010-01-22 · Restriction Enzymes from New England Biolabs With 35 years of experience in enzyme technology, New England Biolabs leads the industry

The science and engineering challenges that society faces today are far more complex than those

of 40 to 50 years ago. The best available scientific, technical, and economic information is required

to establish priorities, make decisions, and develop best practices. AAAS manages the Science &

Technology Policy Fellowships in four areas to provide the opportunity for accomplished scientists

and engineers to contribute to the federal policymaking process while learning firsthand about the

intersection of science and policy. And this is just one of the ways that AAAS is committed to advanc-

ing science to support a healthy and prosperous world. Join us.

Together we can make a difference. aaas.org/plusyou/fellows

Science & TechnologyPolicy Fellows

Page 20: Analyzing genetic differences · 2010-01-22 · Restriction Enzymes from New England Biolabs With 35 years of experience in enzyme technology, New England Biolabs leads the industry

The David Starr Jordan Prize Committeeis pleased to announce the sixth David Starr Jordan Prize Winner:

Dr. Anurag Agrawalof the Department of Ecology and Evolutionary Biology, Cornell University

Dr. Agrawal is one of the foremost authorities on the community and evolutionary ecology of speciesinteractions. Currently an Associate Professor at Cornell (see www.herbivory.com), Dr. Agrawal waspreviously Assistant Professor of Botany at the University of Toronto. An undergraduate at the University ofPennsylvania, he received his PhD at the University of California, Davis in 1999. Dr. Agrawal has madehighly influential contributions, including empirical and conceptual advances in our understanding of plantdefense against herbivory, impacts of genetic diversity on community processes, coevolutionary interactionsbetween monarch butterflies and milkweeds, and deciphering the success of invasive plants. His work hasbeen presented in over 100 papers, has been cited over 3,000 times and has been presented in 75 invitedlectures. He currently serves as an Associate Director of Cornell�s Center for a Sustainable Future.

In 1986, Cornell, Indiana and Stanford Universities established a joint endowment to fund a prize in honor ofDavid Starr Jordan, a scientist, educator and institution builder of enormous influence on higher education inthe United States who had important ties to each of these universities. The prize is international in scope andpresented approximately every three years to a young scientist (40 years of age or less) who is making novelinnovative contributions in one or more areas of Jordan�s interest: evolution, ecology, population andorganismal biology. The intent of the David Starr Jordan Prize is to recognize scientists who are makingresearch contributions likely to redirect the principal foci of their fields. The sixth David Starr Jordan Prizecarries an award of $20,000.00. In addition to a cash award, Dr. Agrawal will receive a commemorativemedal, will attend an award ceremony (this year at Cornell), and visit the other sponsoring institutions to givescholarly presentations of his work.

For more information including a list of previous prize winners and their accomplishments, visit: www.davidstarrjordan.org

Gordon Research Conferences

GRCC iiss pplleeaasseedd ttoo aannnnoouunnccceeee ttthhhee 22011110000 AAAllexaannnnnddddeeerr MMM. CCrrrruuuiiicckkshannnnkkkk LLectureerrrssss:GRC is pleased to announce the 2010 Alexander M. Cruickshank Lecturers:

e Booara ddd of Trur stees of the Gooro don Reesearch Con eeferrences established thee BoBoarararrdddd ofof TTrur stees off tthe GGGGooroo don Reeses arch Connfefeferrer nces established theexanndder MM. C uruickshannk Lecttureresexanandeded r MM. CCruruici kshanknk Lectutureres to hoonor the manynyyyny years of service to theg y dgaanininizazationon bbyy fformer ddiirector,r, DDr.r A.M. CCruickshank. LLeLeLecturers are nominated

tCConfeerrencnce Chairsrs and ccaannddidateess are selectedddd based on their currentj pr p p eeararcch aannd the sububjject ooff tthheeir propoposed lecture.. TTTThree to four recipients are

yy p pp dosenen annuallyy aand haavve tthheir cononfference fee annnnddd travel expenses supportedonGGRC. Moree ininformmatatioonn abouutt these awardss aaaand conferences is available on

r web ssite atr web sisitte at wwwww.w.ggrc.orgg.

The Board of Trustees of the Gordon Research Conferences established theAlexander M. Cruickshank Lectures to honor the many years of service to theorganization by former director, Dr. A.M.Cruickshank. Lecturers are nominatedby Conference Chairs and candidates are selected based on their currentresearch and the subject of their proposed lecture. Three to four recipients arechosen annually and have their conference fee and travel expenses supportedby GRC. More information about these awards and conferences is available onour web site at www.grc.org.

TheAAlex

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ThTThT eTheAAlAAlexAAlexooorgoorgbbbybybyybbyrrreserresechchhoocchobb Gbyby GGbby Goouo roour

tured:d:Pict GRC DiDirector Ememeriritus Alexaxanandder M. Cruickshanknknk, current GRC Director Nancy Ryan

yy, and GGRCRC Directorr EEmeritus CaCararllyle B. StormGrayy

Pictured: GRC Director Emeritus Alexander M. Cruickshank, current GRC Director Nancy Ryan

Gray, and GRC Director Emeritus Carlyle B. Storm

Stanislas Dehaene, Collège de France / INSERMNeurobiology of Cognition GRC

Alanna Schepartz, Yale UniversityBiopolymers GRC

Stanislas Dehaene, Collège de France / INSERMNeurobiology of Cognition GRC

Alanna Schepartz, Yale UniversityBiopolymers GRC

Jorge E. Galán, Yale University School ofMedicine

Microbial Toxins and Pathogenicity GRC

Chad A. Mirkin, Northwestern University

Noble Metal Nanoparticles GRC

Jorge E. Galán, Yale University School ofMedicine

Microbial Toxins and Pathogenicity GRC

Chad A. Mirkin, Northwestern University

Noble Metal Nanoparticles GRC

Page 21: Analyzing genetic differences · 2010-01-22 · Restriction Enzymes from New England Biolabs With 35 years of experience in enzyme technology, New England Biolabs leads the industry

New Products

LIFE SCIENCE TECHNOLOGIESAAAS/Science Business Office

Newly offered instrumentation, apparatus, and laboratory materials of interest to researchers in all disciplines in academic, industrial, and governmental organizationsare featured in this space. Emphasis is given to purpose, chief characteristics, and availabilty of products and materials. Endorsement by Science or AAAS of anyproducts or materials mentioned is not implied. Additional information may be obtained from the manufacturer or supplier.

Electronically submit your new product description or product literature information! Go to www.sciencemag.org/products/newproducts.dtl for more information.

1715www.sciencemag.org/products SCIENCE VOL 326 18 DECEMBER 2009

Pharmaceutical Analysis SystemThe PA 800 plus Pharmaceutical Analysis System is a next generation capillary elec-trophoresis platform designed in collaboration with biopharmaceutical developmentand quality control groups. The robust, easy-to-use characterization platform integratesquantitative, qualitative, and automated solutions for analysis of protein purity, chargeisoform distribution, and glycan structure. The system provides precise quantitation insodium dodecyl sulfate gel analysis, isoelectric focusing, and glycan characterization ofmonoclonal antibodies and other therapeutic proteins. New software guides users fromsetup through operation in routine applications. Modular ultraviolet, photodiode array,and solid-state, laser-induced fluorescence detectors can be readily interchanged.

Beckman CoulterFor information 714-993-8955

www.beckman.com

Intracellular Protein KitsThe In-Cell ELISA Detection Kits provide a simple and convenientmethod for quantifying intracellular proteins in whole cells. Theenzyme-linked immunosorbent assay (ELISA) kit enables the si-multaneous detection of two different target proteins within thesame well (for example, a posttranslationally modified protein andits unmodified form), eliminating the variability caused by differ-ences in cell plating. The kit makes use of primary antibodies tothe target protein(s) and corresponding species-specific ThermoScientific DyLight-conjugated Secondary Antibodies to monitor tar-get protein levels. The kit is compatible with the Odyssey InfraredImaging System. The In-Cell ELISA Colorimetric Detection Kit makesuse of target-specific primary antibodies and a horseradish peroxi-dase–conjugated detection reagent to detect proteins of interest. Tocontrol for differences arising from cell plating, a whole-cell stain isincluded for normalization.Thermo Fisher ScientificFor information 815-968-0747www.thermo.com/pierce

Protein Biomarker ServicesNextGen Sciences’ biomarkerexpress is a suite of services thatmove protein biomarkers through the validation and testing pipe-line by addressing the bottleneck of assay development. The assaytechniques, which are based on mass spectrometry technology, areapplicable to a variety of sample types, including biofluids, tissues,cells, formalin-fixed paraffin-embedded tissue, and plants. Themethods decrease the time and cost associated with biomarker de-velopment.NextGen SciencesFor information +44-(0)-1462-685-788www.nextgensciences.com

Mass Spectrometer for ProteomicsThe AB Sciex 5800 is a fast, sensitive system designed to help re-searchers advance the discovery of disease-related biomarkers forpotential use in a clinical setting. The system represents an advancein matrix-assisted laser desorption ionization-time-of-flight (MALDI-TOF) mass spectrometry technology because it enables researchersto identify up to 30 percent more proteins at a rate 10 times fasterthan any other MALDI system now on the market, according to the

manufacturer. The system is combinedwith new processing softwareto form a complete workflow to accelerate proteomics research. Thesystem enables scientists to identify and quantify more proteins incomplex samples.Applied Biosystems/MDS Analytical TechnologiesFor information 508-383-7961www.appliedbiosystems.com

Cytokine AssaysThe Bio-Plex Pro magnetic bead–based human and mouse cyto-kine assays increase speed and improve reproducibility in cytokineresearch. The immunoassays offer the full automation previouslyunavailable with suspension bead arrays. They are multiplex as-says that offer fast and accurate performance for the detection ofmultiple biomarkers in a single experiment, using as little as 12.5microliters of serum, plasma, or other body fluids.Bio-Rad LaboratoriesFor information 800-424-6723www.bio-rad.com

Zone Measuring SystemThe ProtoCOL automatic zone measuring system has new featuresdesigned to improve the speed of analyzing single radial immuno-diffusion (SRD) plates, so flu vaccines can be manufactured morerapidly. The ProtoCOL can generate results from a 16-zone SRD plateof flu vaccines in minutes, 10 times faster than manual analysis.The system’s software supports 21CFR Part 11 and includes a gan-try control, allowing automatic imaging of larger SRD plates whenrequired. These innovative features make ProtoCOL suitable for in-creasing productivity in any good-manufacturing-practices vaccineproduction facility. The ProtoCOL’s computer-controlled, high-reso-lution charge-coupled device camera captures precise zone imagesand its new software automatically assesses not just two pointsfrom around the circular zone (as would be done manually), but si-multaneously analyzes multiple points. The software then calculatesa precise average diameter measurement to accurately indicate vac-cine potency.SynbiosisFor information +44-(0)-1223-727125www.synbiosis.com

New Products

Page 22: Analyzing genetic differences · 2010-01-22 · Restriction Enzymes from New England Biolabs With 35 years of experience in enzyme technology, New England Biolabs leads the industry

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Page 23: Analyzing genetic differences · 2010-01-22 · Restriction Enzymes from New England Biolabs With 35 years of experience in enzyme technology, New England Biolabs leads the industry

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