After watching her twobrothers suffer the devastatingcomplications of diabetes,Eugenia J. Dodson of CoralGables, FL, was determinedto help cure what she called“a most pernicious disease.”She had inherited a modestlegacy from her late husband,but the quiet and unassumingwoman preferred to live afrugal life, invest her money,and grow a fortune that shewould one day give away.

When she died inDecember of 2005, just 24 days short of her 101st birthday, Mrs.Dodson had amassed an estate in excess of$35 million. Despite her affluence, the formerbeautician lived her life without any of thetrappings of wealth because she had a muchhigher purpose for her money. She designatedthe funds be used for cure-focused researchin diabetes and also in cancer, since sheherself was a lung cancer survivor. Two-thirdsof the gift will come to the DRI Foundation,and one-third will go to the University of MiamiSylvester Comprehensive Cancer Center.

“Gene lived a truly selfless life so shecould fulfill her philanthropic goals. Afterher beloved Enloe’s death, she husbandedher wealth and made astute investments inblue chip stocks. Her fortune grew over aperiod of more than 50 years,” said DonaldE. Kubit of Fowler White Burnett P.A., Mrs.Dodson’s attorney and co-trustee of herrevocable trust. “Eugenia Dodson’s finalestate plan was consistent with her profound

desire to fund research to find cures for diabetesand cancer.”

The gift is now the largestfor the Diabetes ResearchInstitute Foundation in its35-year history. The extra-ordinary donation comeson the heels of a stream of multi-million dollar gifts the Foundation hasreceived in just the last yearalone, further underscoringthe DRI’s distinction as a recognized world leaderin cure-focused diabetes

research.The tremendous contributionwill play a pivotal role in enabling theDRI to bring the most promising newdiscoveries to patients more quicklythan ever before.

Robert A. Pearlman, president and CEOof the DRI Foundation, said, “We aredeeply grateful to Eugenia Dodson forcreating such a meaningful legacy. Thislandmark gift will transform the lives ofmillions with diabetes. The funds willsupport new scientific initiatives and create the J. Enloe and Eugenia J. DodsonDiabetes Center for Translational Research,where DRI scientists can harness the powerof many emerging technologies to cure thisdevastating disease. The significance of thisgift cannot be overstated in terms of what itwill mean for people living with diabeteswho look to the DRI with hope.”

Foundation National Chairman Marc S. Goodman said that a donation of this

Diabetes Research Institute FoundationFall 2006 / Volume 35, Issue 1

www.diabetesresearch.orgDRIfocusM i a m i • N e w Y o r k • L o n g I s l a n d • C a l i f o r n ia • W a s h in g t o n , D .C .

Diabetes Research Institute FoundationReceives $23 Million Gift from Donor EstateGift is the largest in its 35-year history

Mayor Michael R. Bloomberg commendedthe DRI's research progress.

Patti LaBelle wrapped up the Hamptonssummer season with a private concert.

Despite diabetes, Adam Morrison wasthe third overall NBA draft pick.

An Evening Under the Stars

Morrison's Parents Speak Up

(Article on page 14)

D.R.E.a.M.S. Come True(Article on page 11)

(Article on page 7)

(continues on page 3)

Eugenia “Gene” Dodson

Jill VinerJoins DRIF National Board

Dear Friends,

As you read in our coverstory, the Diabetes ResearchInstitute Foundation hasreceived the largest gift in

its 35-year history from the late Eugenia J. Dodson,a woman who, literally, wanted nothing more than tosee a cure for diabetes, a disease that took the livesof both of her brothers. Having survived lung cancerherself, she designated that her entire estate, valuedat more than $35 million at the time of her death, beused for cure-focused research in these two diseases.

Her story is truly remarkable and her selflessgenerosity is certainly unparalleled. We don’t oftenhear stories about people who give up life’s luxuriesin order to help mankind. Eugenia “Gene” Dodson’slegacy will live on through the millions of peoplewho will ultimately benefit from her kindness. Andher and her family’s names will live on through thepermanent funding vehicles that will help speedprogress toward a cure.

This tremendous gift affords the DRI with greatopportunities to build upon its current researchprograms and apply cutting-edge technologies thatare first becoming available to the scientific community.The DRI is pursuing new directions for restoringinsulin production and assembling new researchteams to investigate promising pathways in tissueengineering, cell regeneration, protein therapy,nanotechnology, and many other emerging technologies.

We are witnessing a very exciting time for ourorganization. This recent gift, while by far the largest,is the latest in a stream of multi-million dollar giftsthe DRI Foundation has received over the last severalmonths alone. As more and more people learnabout the DRI’s cure-focused research programsand see the results from their charitable investment,the DRI Foundation has become the organization ofchoice for their contributions.

Many of these generous individuals were honoredat our Cycle of Discovery Donor Appreciation events,held in Florida and New York City last spring. Butgenerosity does not only come in the form of

money, as many dedicated people are responsiblefor creating and producing the successful fundraisingevents throughout our regions. Please take the timeto read about the tireless efforts of these committedvolunteers. We extend our gratitude to all of themfor giving their time and resources to help fulfill ourgoal of a cure.

I also want to thank each of you for your continuedsupport. While we have received some extraordinarygifts, this only raises the bar for what we mustcontinue to do. We are committed to giving Dr. Ricordiand the whole DRI team the resources they need toexpand even further and pursue every single directionpossible to cure all of our loved ones.

Sincerely,

Marc S. Goodman

A Message from the Chairman

2

The Diabetes Research Institute Foundationis pleased to announce the appointment of JillViner to its national board of directors. Jill'spersonal connection to the Diabetes ResearchInstitute dates back several decades. She is agraduate of the University of Miami, and duringher years in college, she attended the Love andHope Ball with her parents.The family's interestin supporting type 1 diabetes research wassparked when Jill's brother, Craig Silver, wasdiagnosed with the disease as a child.

Jill has continued to champion the cause and says that finding a cure fordiabetes has become her top priority. She and her husband, Cliff Viner, havebecome major supporters of the DRI Foundation, and recently made a six-figure gift.

“So much progress is being made at the DRI, and I think we’re so close to a cure.Now that my children are older, I have the time, the energy, the drive and the desire todo whatever I can to make this dream a reality.This is where I belong now,” said Jill.

Not only is Jill a contributor, she has helped steer other donations to the DRI. InJanuary of 2005, she was honored by Chanel and Saks Fifth Avenue/Boca Raton atan elegant luncheon and fashion show held at the Boca Raton Resort & Club. Jillwas instrumental in having the Diabetes Research Institute named as the beneficiaryof this successful event. She also underwrote all of the expenses in order to channelthe maximum proceeds to the organization.

This past August, she and Cliff hosted more than 300 people in theirHamptons home to raise awareness and funds for the DRI. The philanthropiccouple engaged top Miami event planner Barton G. to produce a spectacularevening of food and drink, complete with a concert by Patti LaBelle. Again,Jill Viner and her good friend, Barton G., underwrote the entire cost so thatall of the money raised would benefit the DRI.

In addition to supporting the DRI, Jill has enriched her community inmany other ways through her concern for humanity, particularly children.One of the programs she established, The Viner Compassionate CareProgram, created in 1995, provides financial assistance to families dealingwith a temporary crisis, such as a medical emergency, helping with mortgagepayments or providing for children during the holidays.

Through Camp Breakaway, another component of the VinerCompassionate Care Program, more than 50 children are able to attendcamp every summer. The program provides children with a safe, nurturingenvironment while exposing them to new experiences and enhancingtheir self-esteem.

Jill has also used her many talents to chair numerous fundraising eventsthroughout Palm Beach County. She is an executive board member of theRuth Rales Jewish Family Service, and is also vice president of specialevents and fundraising.

Jill, her husband, Cliff, and their two daughters live in Boca Raton, FL.

magnitude affords a unique opportunity tomove the DRI’s research forward. “This is anextraordinary gift from a remarkable woman.We are very fortunate to be the beneficiary ofsuch self-sacrificing generosity, and lookforward to stewarding Mrs. Dodson’s gift tofulfill her dream of a cure for diabetes,” he said.

The tremendous funding also comes at atime when the Diabetes Research Institute isexpanding its research programs and applyingthe newest technologies in biomedical researchto restore insulin production. New scientificteams at the DRI are delving into such areasas cell regeneration, tissue engineering, celltransdifferentiation, and nanotechnology,amongother cutting-edge areas that arejust beginning to show promise in earlyresearch studies.

“This couldn’t come at a better time.Mrs. Dodson's generous gift willallow us tocreate new programs and expand existing onesin several critically importantareas of diabetesresearch where progress needs to be made.Not only will we be able to jump start researchimmediately in these areas, but we will also beable to bring in additional top tier scientistsand theirteamsto Miami to work with us inthese important initiatives," explains CamilloRicordi, M.D., scientific director and chiefacademic officer of the Diabetes ResearchInstitute. “I’m very optimistic that we cancreate final strategies that work.”

How the Gift Will Be UsedTo perpetuate Eugenia Dodson’s legacy

and pay tribute to her remarkable generosity,the DRI will establish several permanentfunding vehicles that bear her and herfamily’s name. The incredible gift allows theDRI to expand current research activities,explore promising scientific areas, and develop new treatments:

• The J. Enloe and Eugenia J. Dodson Chairin Diabetes Research at the DiabetesResearch Institute at the University ofMiami Miller School of Medicine

• The J. Enloe and Eugenia J. DodsonDiabetes Center for Translational Research

• The Raymond and Russell JohnsonFellowship in Type 1 Diabetes Research

• Purchase highly-specialized and tech-nologically advanced research equipment

• Fund new scientific initiatives in cutting-edge areas of diabetes research:

Drug Discovery Program for ToleranceInduction.Currently, DRI scientists areonly able to choose among those drugs thatpharmaceutical companies make available.The DRI is working to overcome thesebarriers by assembling a special DrugDiscovery Research Team to develop thenecessary immune intervention agents thatwill be owned by the DRI and used withoutconstraints. Production and use of its ownagents will also speed the discoveryprocess of bringing new drugs to patientswith diabetes.

Tissue Engineering Program. The DRI’sTissue Engineering team will be expandingits programs beginning with the recruitmentof Dr. Cherie Stabler from Emory University(see related article on page 8). DRI scientistswill be developing new biocompatiblematerials and other technologies to “activelyprotect” islets and promote long-termsurvival and function after transplantation.

Drug Delivery of Bioactive Moleculeswithin the Transplant Microenvironment.DRI scientists, in collaboration with theUniversity of Miami Bioengineeringdepartment, are working to develop ways tosupply islet cell grafts with better nutrientsand oxygen, as well as protect the cellsin the transplant microenvironment. Thisintegrated approach may help create morefavorable conditions for long term isletsurvival and function after transplantation.

Beta Cell Biology Program Expansion. DRI scientists are improving upon methodsto reliably and accurately assess the qualityof insulin-producing islets prior to trans-

plantation into patients. The DRI is usingan advanced laser scanning technology todetermine the health and number of cellswithin each islet. New avenues of investi-gation also measure the level of calciumthat enters islet cells in response to glucose,allowing them to release insulin. The levelof calcium corresponds to the amount ofinsulin released, which is a measure ofislet viability.

Islet Cell Regeneration. New evidencesuggests that islet cells have the potentialto regenerate in the human pancreas. DRIresearchers are testing several methods tostimulate islet regeneration using hormones,growth factors and new drugs. They are alsoworking to identify the factors that regulatethe formation of insulin producing cells thathave been observed in the pancreatic ducts.

For more information on these and othernew DRI research programs, please see theEmerging Technologies section of our websiteat www.diabetesresearch.org

To learn more about the ways you can create a legacy by supporting the DRIFoundation, and take advantage of tax savings through estate planning techniques,visit the new and more comprehensiveplanned giving section of our website. Visit www.DRI.plannedgifts.org or contactJill Shapiro Miller at 1-800-321-3437.

Gene’s brothers, Russell and Raymond Johnson,both died from complications of diabetes.

3

1. 2.

Gift is the largest in its 35-year history(continued from page 1)

1) Gene was a remarkably selfless woman whoseultimate goal was to fund research for diabetes andcancer. 2) J. Enloe Dodson, “the love of her life,” leftGene a modest legacy 50 years ago.

4

Awards from the DRI Foundation's Cycle of Discovery series were recently presented to donors who made major gifts during 2005-2006. The award programcorresponds with the Foundation's cumulative giving designations below.

Foundation Donors Recognized

1. 2. 3.

9. 10. 11.

13. 14.

18. 19. 20.

21.

5. 6. 7.

1. 2. 3. 4.

10. 11. 12.

13. 14. 16.15.

17.

6. 7. 8.

22.

Benefactors $25,000+ QueryFounders $50,000+ HypothesisGrand Founders $100,000+ ExplorationDistinguished Humanitarians$250,000+ RealizationGovernors’ Society $500,000+ TranslationLeadership Council $1,000,000+ PerpetuationChairman’s Council $5,000,000+ ValidationVisionaries $10,000,000+ Innovation

DONOR LEVEL AWARD

5

1) Michele Bowman and Colonel Joseph Underwood, Perpetuation; 2) Ricardo Puente and his fiancée, Misty Flanders, Perpetuation; 3) Michael Davis,Nurit Gans, and David Kay of the Foundation for Diabetes Research, Translation; 4) Milton J. Walters of Million Dollar Hole-in-One Marketing, Translation;5) Ivette and Juan Elias Calles, Realization; 6) Bill and Joan Fishlinger, Realization; 7) Piero Gandini, accepting for himself and his wife, Paola, Realization;8) Martin Granowitz, Realization; 9) Larry and Bonnie Inserrra receive Realization from Northeast Director Sandy Cahn; 10) Risa and Jeff Pulver, Realization;11) Jill Viner, Realization; 12) Barry and Carole Kaye, Exploration; 13) Mac and Pat Levitt, Exploration; 14) Jacci and Dr. Floyd Seskin, Exploration; 15) Nancy Smith of the Marion A. Roletti Foundation, Exploration; 16) Leonard and Anna Thun, Exploration; 17) Irving and Phyllis Bernstein and Myronand Barbara Bloom, accepting on behalf of the Family of Dr. Adam H. Bloom, Hypothesis; 18) Martin and Gladys Gelb, Hypothesis; 19) Elaine andHerbert Gimelstob, Hypothesis; 20) Shari Gantman of The Health Foundation of South Florida, Hypothesis; 21) Arthur Hertz, Hypothesis; 22) Richard C.Hsia of the Future Leadership Foundation, Hypothesis; 23) Martin and Joan Maddaloni, Hypothesis; 24) “Spa Maven” Sondra Rose, Hypothesis; 25) Sonia Gibson and Deborah Slack of Saks Fifth Avenue Bal Harbour, Hypothesis; 26) Olga and Carlos Saladrigas, Hypothesis; 27) Doug Tannehill ofC.H. Robinson Worldwide, Hypothesis; 28) Sari and Michael Addicott, Query; 29) Deidre Costa Major, accepting on behalf of Rita and Frank Castagnaof the Americana Manhasset, Query; 30) Joe Cerniglia (right) of Florida Mushroom accepts Query from Florida regional board member Bruce Fishbein;31) Jane and Lawrence H. David, Query; 32) Peter L. DiCapua of Atco Properties and Management, Inc., Query; 33) Camilo Lopez of Florida Associationof Furniture Manufacturers, Query; 34) James Kenyon of Steelcase, Query; 35) Bill and Laurie Landau, with their daughter and son-in-law, Nancy andJosh Gillon, Query; 36) Laura Marinello and Marcy Jurkowitz of City National Bank, Query; 37) Allan Pashcow, accepting for himself and his wife, Louise,Query; 38) Norman and Myrna Ricken, Query;

23. 24. 25.

30.

31. 32. 33. 34.

35. 36. 37.

26.

27. 28. 29.

38.

39) Patty and Leonard Schupak, Query; 40) Barbara and Norman Shapiro, Query; 41) June Zanvardine and McKenzie Richards of Abbott Diabetes Care, Query;42) Shirley Hotto, Heritage Society.

66

42.39.

Paula Wilson's resume reads like an eventplanner's date book. Driven and dedicated, she hasspent the last two decades volunteering andfundraising for a number of organizations whilejuggling home and family.

Years back, she took on the requisite roles ofGirl Scout troop leader and PTA president, and was aregular fixture at her two daughters' school events,often acting as book fair chair, hospitality chair orserving on numerous committees and councils. Shehas also led Sunday school classes and organizedvarious fundraising and youth events at her church.

Paula devoted whatever free time remained toher love of the arts, where she tested her creativityin different acting roles.

Her tireless dedication to these many worthyactivities, however, pales in comparison to thepassion she and her husband, Tom, have broughtto their most important cause of all — finding acure for type 1 diabetes, the disease that strucktheir eldest daughter 17 years ago when she wasjust 3 years old.

Together, Paula and Tom immersed themselvesin Diabetic Youth Services, Inc. (DYS), a nonprofitorganization they founded with three other couplesin 1996. The organization was formed for onepurpose — to support and maintain Camp Conrad-Chinnock, a Los Angeles summer camp for kidswith diabetes that had lost its funding.

In addition to fundraising and volunteering forthe camp, Paula was employed as its director of

development. Through writing grants and rallyingsupport from numerous individuals and organizations,Paula helped propel the camp from foreclosure to afinancially stable, smooth-running organization.

Their support of diabetes-related causes fannedout into other areas. They participated in annualbike-a-thons, and Paula even chaired a comedybenefit for DYS.

And today, she finds herself in another leadership role as chairman of the DRI Foundation'sCalifornia regional board of directors. After joiningthe board in 2003 and chairing several of theFoundation's fundraising events, Paula was selectedto head this dedicated group to help make an impactin the vast California market.

“Our passion has always been for the camp,”said Paula. “But when we heard the DRI's Dr. LucaInverardi speak there, we learned that there wasgreat hope for a cure. Now our daughter, Nicole, is acounselor at the camp, teaching kids to live with theirdiabetes, so we can focus our energy on the cure.”

“There are two things about the DRI that really excite me,” she explained, “the fact that thework is cure-focused, and that DRI scientists sharetheir results.”

Recently, Tom and Paula visited the DRI. Duringtheir tour of the Institute, Paula was vividly remindedof the words she would often repeat to her daughter.“Since she was in kindergarten, I would tell Nicolethat every day people are going to work, and theirjob is solely to find a cure for diabetes. Every day

they're getting a little bit closer.” On that day, Paulawitnessed her anecdote brought to life.

Having gotten her feet wet as chair of theFoundation's Finding Nemo and The Incrediblesbenefit screenings and last year's Laugh for a Cure,Paula is now taking on the fourth annual Stand Upfor a Cure comedy event, scheduled for November12 at The Improv in Los Angeles.

But in her larger responsibility as chairman ofthe board, her focus is to broaden sources offunding, differentiate the DRI Foundation fromother local diabetes organizations, and build uponprevious successes.

“We want to move in the direction of addingmore fundraising elements. I want SouthernCalifornians to know that their dollar will go a littlefurther at the DRI,” she said. “Finding the curemust be a collaborative effort, and I think that'swhat makes the DRI very, very special.”

Paula Wilson:Passion Personified

Foundation Donors Recognized(continued)

Paula Wilson serves as Chairman ofthe California board of directors.

4140.

Want to know more?• Learn about Adam's initial diagnosis and how the Morrisons dealt with it together.• Read about the family's history of type 1 diabetes and Adam's introduction to basketball at the age of 13 months! • View additional photos and more.

For the extended article, please visit our website, www.diabetesresearch.org.

7

Wanda and John Morrison have mastered theart of teamwork. It's apparent in conversation as eachfinishes the other's last sentence. Maybe it stemsfrom a solid foundation and 32 years of married life.Perhaps it ripened over time as they raised threechildren together, or sprung from necessity whentheir youngest was diagnosed with type 1 diabetes.Wherever it originated, this warm and loving couplehas passed the asset along to their kids, andespecially to their youngest child, Adam Morrison,22.Selected by the Charlotte Bobcats as the thirdoverall pick in the 2006 NBA draft, Adam has takenthis team mentality to a whole new level, whileovercoming the challenges of this disease.

“There are several professional athletes thatplay a variety of sports, and they have diabetes,”said John of his son. “I think being into athleticshas actually helped Adam stay in control of thisdisease — the discipline, the practice, his workethic, and tenacity. He refuses to lose.”

“He's a warrior, on the court and off,” Adam'smother, Wanda, added. “He'll do whatever it takesto win. That aspect of his personality comes outwith his diabetes, too. He won't let anything interferewith his dreams.”

However, that wasn't always the case.Diagnosed at 14, Adam avoided the dreaded

label of being “different” by heading to the bathroomwhen he needed a shot of insulin at school.On thecourt, this new life-necessity turned into a nuisance.

Wanda explained, “He just didn't want to leavethe game.It took a while for him to get used to it.”

His devoted mom would sit directly behind thebench, assisting in glucose checks during time-outsand carrying an arsenal of insulin and snacks.Wanda remembered one heart-wrenching experiencewhen as a high school junior Adam suffered asevere insulin reaction during a game.

“He said to me, 'Mom, there's only one thingthat can stop me, and that's diabetes.' My heartached,” said Wanda, but that moment was theimpetus that led the family to a nutritionist, whoprovided them with a better understanding of howto control the disease and got Adam on the righttrack to an enormously successful career. “Toughas it was, that was the trigger for getting Adamwhat he needed to excel.”

A prolific scorer, Adam averaged more than25 points per game at Gonzaga University, locatedin his hometown of Spokane, WA. The 6-foot-8,205-pound forward led the NCAA's Division-1 inscoring last season and was hailed West CoastConference player of the year before announcingthat he would forgo his senior year for the NBA. Anaggressive competitor with a killer instinct and awicked jump shot, Adam is adored by fans for hischarismatic personality, trash-talking tongue, andthat trademark, patchy mustache that earned himthe nickname, “The Stache.”

In college, he perfected his pre-game ritual toa science in order to keep his glucose levels undercontrol. On game day, he eats the same meal twohours and 15 minutes before tip-off, using a pumpthrough warm-up, disconnecting and taking insulinmanually if necessary during the game. Then, hehooks back up to the pump after the buzzer.

Despite the myriad accolades Adam receivedthroughout college — plus the fact that he's aclutch performer who can get a shot off fromanywhere, some teams might have considered hisdiabetes to be an insurmountable obstacle. However,after selecting Adam, it's clear that Michael Jordan,the new basketball operations chief and part ownerof the Charlotte Bobcats, believes he has what ittakes to outrival opposing defenses during the 82-game pro schedule.

Adam's style of play has drawn comparisonsto Larry Bird, and not so coincidentally, the Hall ofFamer is Adam's favorite baller to have ever playedthe game. But it's comparisons to former NBA centerChris Dudley, who played with type 1 diabetes for16 seasons, that has reminded many that diabetesdoes not equate to disability.

Never allowing diabetes to determine hisfuture, and simply by following his dreams, Adamhas set a strong example for his younger fans.

“Adam never set out to be a role model, but Ithink he's become a good one,” Wanda proudlystated of her son, who happens to sign countlessautographs but always takes extra time for kidswith diabetes. “When he was first diagnosed, Adamdidn't really have a mentor with diabetes to look upto. That's why it's so important to him now — tobe that person for others.”

If Wanda and John can offer any advice toother families like theirs, it is to always encourageyour children to chase their hopes and dreams,regardless of diabetes.

“We worry just like any other parents,” saidWanda of the intense NBA schedule and the possibility of injury that all athletes face. “That'sour little boy out there. Having this disease mightmake a child's dreams harder to reach, but you cannever give up hope,” Wanda said, holding back tears.

The payoff? “Adam's dream has come true, and we are

unbelievably proud of him,” said Wanda.The future?“A cure for diabetes is on the horizon, and we

believe it will happen in his lifetime,” she concluded.

STANDING BEHIND “THE STACHE”Wanda and John Morrison speak up about their star athlete son

Moments after the Charlotte Bobcats drafted him,Morrison proudly displays his new team jersery.

At the John R. Wooden Award Ceremony, Wandaand John Morrison stand proudly with their son,who was one of the top ten Wooden All-Americansand one of five finalists for this prestigious award.

DRI Federation Gains New MembersFour additional research centers have joined the Diabetes

Research Institute Federation, bringing the total number ofmembers to 12, and representing 10 countries around theworld. The recently-launched DRI Federation is the only globalcollaboration of its kind that unites leading research centers toconcentrate solely on curing diabetes through tolerance induction,transplantation of islets and other insulin producing cells, stem celltherapies and regenerative medicine strategies. The newestmembers to join this research alliance are:

• DRI-Geneva at the Cell Isolation and Transplantation Center at the University of Geneva, Switzerland

• DRI-Oxford at Oxford University, England, U.K.• DRI-São Paulo at the Universidad de São Paulo, Brazil• DRI-Ümea at the Centre for Molecular Medicine, Ümea

University, SwedenEach partnering center contributes a specific research expertise

to the goal of curing the disease as illustrated in the integratedresearch approach or “roadmap to the cure” that was developed by the DRI and published in 2005 in the journal Transplantation (see diagram).

By entering into this formal alliance, the researchers have agreed to put their individual interests aside and share all knowledge and information in what is typicallya very competitive environment. The achievement of the overall goal — a cure for diabetes — is the driving force behind this worldwide collaboration.

For more information on the DRI Federation, please visit our website at www.diabetesresearch.org

DRIAround the DRI Dr. Camillo Ricordi ReceivesTransplant AwardCherie Stabler, Ph.D., to Head DRI Tissue Engineering Lab

The Diabetes Research Institute is pleased to welcome Cherie Stabler, Ph.D., asDirector of the Tissue Engineering Lab. Dr. Stabler comes to Miami from EmoryUniversity School of Medicine in Atlanta, where her research focused on the design anddevelopment of islet encapsulation techniques and the study of how biomaterial barrierscan protect the fragile implanted cells from the strong immunological and inflammatory responses of the recipient.

Tissue engineering holds great promise for enhancing islet survival.At the DRI, Dr. Stabler's research will buildon existing methods to construct new biocompatible barriers, such as complex “scaffolding,” that may offer moreimmuno-protection to the transplanted islets.

She will also investigate ways to attach specific proteins within or on the surface of the protective barriers, such asanti-inflammatory agents.By combining biomaterials with active proteins, it may be feasible to generate materials capable of“actively” enhancing the islet environment, thereby resulting in increased survival and function of the insulin producing cells.

Another area of Dr. Stabler's research involves the use of noninvasive imaging techniques, specifically MRI and MRS(Magnetic Resonance Imaging and Spectroscopy), to assess tissue engineered implants.By applying MRI/MRS techniques toislets, researchers hope to monitor the structure and viability of transplanted islets without disturbing their environment.The ability to observe islets post-transplant is critical for understanding their function over time. Dr. Stabler's workcomplements the DRI's current efforts to assess the health and quality of islets prior to transplantation into patients.

“I am very excited to have the opportunity to work at the DRI where there is a team that combines every aspect ofdiabetes research, as well as a strong focus on tissue engineering. It's really unique,” says Dr. Stabler. “I'm also veryimpressed with the willingness of Dr. Ricordi and the whole Institute to openly share their work with the research community.The DRI is regarded worldwide as a top-notch research facility.Joining their team for the research reputation is wonderful,but going there for the research collaboration makes it even more meaningful.”

In July, DRI Scientific DirectorCamillo Ricordi, M.D., received TheTransplantation Society Roche Awardfor Outstanding Achievement inTransplantation Science (Clinical).The award was presented duringthe World Transplant Congress, thelargest biennial international trans-plant event that took place this yearin Boston.

The Transplantation Society'srecognition awards are given to arecipient who has made outstandingcontributions in transplantation.

8

Dr. Kathryn J. Wood, president ofThe Transplantation Society, andZuzana Lindberg of Roche presentthe award to Dr. Ricordi.

For the past 12 years, Dr. AlbertoPugliese, a Research Associate Professorof Medicine, Immunology andMicrobiology at the Diabetes ResearchInstitute (DRI), has focused his workon how genetic resistance impactsinsulin-dependent diabetes. His researchhas allowed him to uncover novel ideasthat may better help him and his co-inves-tigators understand the complex natureof this disease.

As part of his current NIH grant supporting his research on autoimmunity,Dr. Pugliese is looking into the idea thatinsulin-producing cells may regenerate.He is also investigating the possibilitythat certain cells may “transdifferentiate,”that is to say a cell may be able to changeits function when necessary for survival.

By taking this multi-prong investigativeapproach, Dr. Pugliese, who is also the headof the Immunogenetics Program at theDRI, suspects these two phenomena mayprovide further insight into the problem ofautoimmunity as it relates to the rejectionof pancreatic and islet transplants.

Furthermore, if the theories about cellregeneration and transdifferentiation canbe proven and replicated, doctors couldprovide treatments for their patients notonly to ameliorate the disease, but per-haps to reverse the onset of type 1 dia-betes altogether.

Q: In your August 2005 article publishedin the Journal of Immunology, you discussed your study of dendritic cells and

type 1 diabetes. How could the results ofyour study impact those suffering fromthis disease?

A. In the article, we showed that dendritic cells may be a key in thedevelopment and sustenance of 'self-tolerance' in the human immune system.(Self-tolerance is the immune system'sability to recognize insulin as a goodhormone, for example, and therefore notattack it.) Our group was the first to showthat human dendritic cells in the thymuscan express insulin and that these cellscan also be found circulating in the body.This discovery may be a key to why somepeople develop diabetes or otherautoimmune diseases. We suspect theamounts of insulin expressed in thethymus and by the dendritic cells controlthe risk of developing autoimmunity thattargets insulin and, in turn, pancreaticbeta cells. If this source of insulin isreduced, the body may see insulin asforeign. If this happens, the immunesystem will see insulin-producing cells as foreign, as well, and attack, destroyingbeta cells and creating a diabetic state.Our goal is to discover the molecularmechanisms that allow the dendritic cellsto express insulin so that they could beused to treat people with diabetes byreining in unwanted autoimmuneresponses against the islets. This alsomay be relevant for the long-term successof islet transplants.

Q: You say that ductal cells could becomeinsulin producers. Why is this important?

A. We noted in several patients whoreceived pancreas transplants that theductal cells, cells that make up thestructure of the pancreatic duct, in thetransplanted organs expressed insulin.This is not a normal finding, as insulinis only expressed in beta cells. Thisphenomenon may be a way of compensat-ing for the loss of insulin-producingcells, whereby cells that do not normallyproduce insulin change their role in thebody and in fact start producing insulin.We are putting much time into this“survival technique” theory, which is also

backed up by studies in rodents. If we atthe DRI can discover the necessary elementsthat cause this transdifferentiation, wemay be able to learn how to promote thesechanges and the formation of new betacells in people with long-term diabetes.There are many different mechanismsinvolved here and the situation may bedifficult to mimic. But by studying theductal cells that express insulin in thesepatients and investigating their geneticprofile, we may discover genes that play akey role in this phenomenon. Novel tech-nologies available to the scientists at theDRI, such as laser capture technology andgene chips, should allow us to studythese key pathways on a molecular level.

Q: Islet transplants at the DRI continueto show promise. What studies are youcurrently involved in?

A. One of the projects we are involvedin through the Immunogenetics Programis the monitoring of islet transplantpatients for several types of immuneresponses associated with the developmentof type 1 diabetes. We can test theseresponses to see if they are factors in thelong-term survival of a transplant. Wealso are establishing assays to monitor thenumber of autoimmune cells circulating inblood. These are not the T-cells thatcause rejection of the islets but immunecells that specifically target insulin-producing cells - the same kind ofimmune cells that cause diabetes in thefirst place. We need to find out if theimmunosuppressive drugs that preventrejection can also keep these immunecells from coming back. If we obtainevidence that these cells return andnegatively affect the transplanted islets,then we need to find ways to block them.There are several ongoing studies thatare evaluating therapeutic regimens thatmay have efficacy, and those studies willprovide information that is relevant toislet transplant patients, too. In the end,we need to make sure that the immunesystem is properly controlled to ensure thatit does not harm the transplanted islets.

9999

with Alberto Pugliese, M.D.

Under the Microscope

1) Alexander Smith, Shane Wilsonand Lucas Wilson scale the rock-climbing wall.2) With the help ofa Deliver the Dream volunteer,Alexander Alonso assists 2 1/2 -year-old Giancarlo Alfonso as he petsa calf at the petting farm. 3) Toddand Samantha Green peer over theshoulder of Hope the Bear at CharlotteYedo, Jake Miller, and GiancarloAlfonso, during welcoming activities.4) Many of the families met at theDRI and traveled together by bus.Pictured: (back row) Stephanie Yedo,Alexander Alonso, Gabriela Sullivan,Madeline Yedo, Karen Ripoll, CharlotteYedo; (aisle) Patrick Sullivan, BrookeMiller; (seated) Emma Dorante,Emmanuela Diaz, Giancarlo Alfonso,and Maria Rodriguez.

Thirteen families from South Florida's tri-county area, with kids of varying ages,backgrounds and ethnicities, gathered for the Deliver the Dream Retreat Weekend atthe Westgate River Ranch in Lake Wales, Florida. Their many differences were minimalincomparison to the one thing they did share — a connection to diabetes.

For the long weekend of April 6-9, the Diabetes Research Institute partnered withDeliver the Dream, a not-for-profit organization that provides a respite for families facingserious illness or crisis by helping them to enhance coping skills, reduce stress andcultivate relationships. Many of the kids with diabetes at the retreat had never evenmet another child with the disease and were happy to experience an environment wherecarb-counting and glucose testing was the norm.

On the first evening, the families sat around the campfire, singing songs, roastingmarshmallows and eating s'mores. Though their blood sugars skyrocketed, thepump-users couldn't wait to compare correction bolus counts the next morning.Additional weekend activities included horseback riding and pony rides, fishing, miniaturegolf, airboat rides, archery and swimming, plus a costume party, a petting farm, teenmovie nights, a rodeo, and so much more.

The DRI's Ana Maria Avila, Allison Wick, MSN, ARNP-C, CDE and Jane Sparrow-Bodenmiller, RN, CDE, C.P.T. were on site to ensure a safe, healthy atmosphere, andWendy Rappaport, Psy.D., L.C.S.W. led separate discussion groups for moms, dads,and kids. Then,she brought everyone together for some surprising realizations.Parents explained their constant concern regarding their kids with diabetes; siblingsrevealed their true emotions; and those with diabetes were able to see life from afresh perspective.

At the retreat's end, all the participants exchanged phone numbers, email addressesand promises to keep in touch. Though they arrived as strangers, each individual left with ashared sense of belonging and a network of new friends who live close by.

An unforgettable weekend retreat

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2.1

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The inaugural D.R.E.a.M.S. (Diabetes Research, Elegance and ModernSophistication) in the City event impressed more than 200 guests at New York'sWest Side Loft on May 18. Co-chaired by Northeast regional board membersRisa Pulver and Samantha Shanken Baker, the event raised nearly $240,000.

“The idea of the event was to have fun, get together for a good causeand raise funds to find a cure, and we achieved all three,” said Samantha.“D.R.E.a.M.S. in the City truly showed how New Yorkers love to step forwardfor a good cause in order to make a difference.”

Honorary Committee Member Joseph R. Gannascoli, better known to fans of"The Sopranos" as Vito Spatafore, mingled with the crowd as they enjoyed fabu-lous food and drink, plus music by DJ Tom Finn, formerly of Studio 54. Theevening was highlighted by an appearance by Mayor Michael R. Bloomberg whowas introduced by DRI Northeast Board Chairperson Tom Stern. MayorBloomberg spoke eloquently about New York City's commitment to support diabetesresearch, and he commended the high quality of research underway at the DRI.

“We were all moved that Mayor Bloomberg took time from his hecticschedule to join us for a good cause," said Risa. "His words of support in thedrive to find a cure were deeply felt by everyone in the room.”

The evening featured a stellar silent auction, with such spectacularitems as a weekend at Twin Farms in Vermont, exquisite jewelry from Loree

The “Hippest Happy Hour in Town” played out its moniker Saturday,June 3, at the 15th annual Feast Among the Grapes, South Florida's premierwine tasting and culinary event, held in cooperation with Wine Spectator.More than 1,000 guests glided from booth to booth at the Radisson HotelMiami, sampling savory snacks and tantalizing treats from Miami's finestrestaurants, plus a rainbow's spectrum of beverages and spirits. The trendysoiree raised more than $161,000 for the DRI.

Standing in the center of the room, a large, handsome, oak bar, courtesyof ME Production, became a gathering point of the evening as many guests,including Honoree Joey Krutel, enjoyed chilled martinis. Oohs and ahsescaped the mouths of attendees who tasted the shrimp and jasmine ricedumplings with green apple curry created especially for the event and servedup by Chef Chair Michael Bloise of Wish. Both Krutel and Bloise committedthemselves to the Diabetes Research Institute after losing their fathers to

...a dream come trueD.R.E.a.M.S. in the City

HIP HIP HOORAY!diabetes-related complications. The passion and endless efforts of these youngmen were evident in the success of this very hip party.

Revelers returned again and again to Café Sambal's station, where Chef GerdyRodriguez offered smooth, green mojito shots and braised beef short ribs with potatofoam and candied onions. Perricone's Marketplace gave pasta lovers a healthyalternative, whole wheat fusilli reggiano, and Tropical Chinese Restaurant offered adelectable Peking duck. Kefi presented an extravagant Mediterranean antipastispread as well as mouth-watering chocolate mousse. Guests with a sweet tooth alsoenjoyed Schakolad Chocolate Factory's cascading chocolate fountain andmarshmallow lollipops, CrepeMaker's dessert crepes, The Melting Pot's chocolatefondue with strawberries, Key lime crème brulee from North One 10, and much more.

Other restaurants making scrumptious contributions were: 3030 OceanRestaurant, Bizcaya Grill at the Ritz Carlton in Coconut Grove, Cacao Restaurant,Café Ragazzi, Carltons Restaurant & Lounge, Joanna's Marketplace,LaEstanciaArgentina, Mario the Baker, Neomi's Grill at the Trump InternationalSonesta, PAUL Bakery & Café, Shulas Steak House at the Alexander Hotel, SushiHouse, Sushi Republic, The Forge, Timo, and Touch.

New friends cozied up together on white love seats in the posh VIP lounge,sponsored by Rand Eye Institute, where hors d'oeuvres were passed and champagneflutes bubbled over. VIPs were also treated to: a special silent auction, containingultra-fabulous prizes; a huge, martini-shaped, icy luge dispensing espresso-flavoredVan Gogh vodka; Daquiri Dog's frozen margarita machines; The Boutique Kitchen'sWest Indian style fish cakes with roasted pepper sambal; and more.

Live music by The Fit seduced movers and shakers onto the dance floor, andmore than 200 exciting silent auction prizes, including several luxurious vacationand local entertainment packages, plus the best of fashion, sports, art and more,spurred exhilarating bidding wars.

Chairpersons Barbara Amoils, David Walker, Andy and Judy Waks, and RandyFurshman offered special thanks to top sponsors including: Wine Spectator, RandEye Institute, Southern Wine & Spirits of South Florida, Premier Beverage Company,National Distributing Company, Dr. Floyd and Jacci Seskin, FlosUSA, Comcast,Love 94, The Miami Herald, Crown Wine & Spirits, Van Gogh Vodka, CarnivalCruise Lines, Biorep Technologies and Franz Franc Design Group.

1) (l-r) Co-chairpersons David Walker, Barbara Amoils, and Andy Wakscelebrated another year of success. 2) Chef Chair Michael Bloise of Wish, shownwith his son, Christopher, passionately pledged his dedication to the cause.3) Joey Krutel was the center of attention as the 2006 honoree.

1. 3.2.

11

Rodkin Jewels and Mayfair Jewelers, a Gucci Bouvier handbag, and an array ofsports memorabilia generously donated by Northeast board member PeterDiCapua. Funds also were raised via naming opportunities, whereby big-hearteddonors pledged to underwrite much-needed equipment for the Institute.

The event chairpersons, along with Junior Chairperson Hayley Friedman Morrisonand the committee, extended their heartfelt appreciation to the many generous peoplewho made the event a success. Diamond D.R.E.a.M.S. Sponsors included: BearStearns, The Stacy Joy Goodman Memorial Foundation, Katten Muchin RosenmanLLP, The Kenmar Group, Risa and Jeff Pulver, Adrienne and Arnold Rubin, and Hazeland Marvin Shanken. Golden D.R.E.a.M.S Sponsorswere: Judy and Jason Chudnofsky, DPM Mellon,Hirshleifer's, Lehman Brothers, Vikki and Michael Price,and UBS Securities, LLC. Silver D.R.E.a.M.S Sponsorsincluded: Citigroup, Doug Davis, Kelly and David Halpert,Edith and Norman Weisfeld, and Diane and Howard Wohl.In-kind sponsors were: Candid Litho Printing Ltd., ColSolare, Gloria Ferrer, Fiji Natural Artesian Water, EmerilLagasse, pulver.com, Wine Spectator, and Yamazaki.

2.

1.

1) DRIF President and CEO Robert A.Pearlman enjoyed speaking with HonoraryCommittee Member Joseph R. Gannascoli(A.K.A. Vito Spatafore of “The Sopranos”).2) Co-Chairs Risa Pulver and SamanthaShanken Baker and Junior Chair HayleyFriedman Morrison enjoyed the successof the event.

Support our Work While Doing Yours

VitaZest offers nine delicious flavors.

1212

other sugary soft drinks over the last four decades hasgreatly contributed to excessive weight gain. Theresearchers contend that an extra can of soda a daycan add up to 15 pounds in a single year.

"With the recent news that beverages withhigh sugar content, especially sodas, are contributingto the obesity problem in America, VitaZest Vitamin& Fruit Enriched Water offers a healthier alternativefor hydration.Because it contains no carbohydratesand no sugar, this flavored beverage is a betteroption for those that need to be careful about theircarbohydrate and caloric intake," said LuigiMeneghini, M.D., Associate Professor of ClinicalMedicine, and Director, Eleanor and Joseph KosowDiabetes Treatment Center at the DRI.

“We are grateful to VitaZest for their supportof our mission to cure this disease and for theirconcern for all people affected by diabetes,” saidRobert A. Pearlman, president and CEO of theDiabetes Research Institute Foundation. “Thispartnership is a natural fit for our organization, and weare looking forward to a very successful relationship.”

Consumers can purchase VitaZest at variousretail outlets across the country, or they can orderdirectly from the company's website at

www.drinkvitazest.com, which offers an addedbenefit. Internet shoppers can get $10 off theirinitial purchase of a single case of VitaZest byentering discount code DRIF10 at checkout. The24-bottle assortment usually retails for $41.99per case so the initial case price for DIRF customersis $31.99. Customers' future purchases of VitaZestwill also be discounted by $2 per case when usedwith the special Diabetes Research InstituteFoundation code,DRIF. When customers place anonline order by the case using the specialdiscountcode, the organization will receive an additionalcontribution. Shoppers can find the discountcode on the Diabetes Research Institute's website,www.diabetesresearch.org.

“We couldn't be more proud of an affiliationwith a leader like the Diabetes Research Instituteand its Foundation, and we'll do all we can tosupport their efforts to find a cure,” said Ziv Alcalay,VitaZest Vice President of Operations. “We lookforward to attending and working with the DRIF attheir events, with their donors and through whateverchannels we can to make sure awareness israised about the fact that VitaZest is a good choicefor consumers, especially those with diabetes.”

New Vitazest®Partnerswith the DRI

The Diabetes Research Institute Foundationand VitaZest® Vitamin & Fruit Enriched Water®, aproduct of Triple A Products, LLC, have teamed upto help consumers quickly identify a healthful andgreat tasting source of hydration.VitaZest contains10 vitamins and minerals, no carbohydrates, nocalories, no sugar, no caffeine, and no preservatives.Even better, a portion of the proceeds of all VitaZestsales will support the Diabetes Research Institute.

The DRI logo will be printed on all VitaZestproduct packaging in the Vitamin & Fruit Enrichedline of waters and other materials to indicate thecompany's commitment to supporting the cure-focused work being conducted at the DRI.The appearance of the DRI logo will immediatelyalert consumers, such as those who have diabetesor who are at risk of developing diabetes, thatVitaZest is a healthy and enjoyable option.

The partnership between VitaZest and the DRIFoundation has been formed at a time when theincidence of diabetes and obesity continues to riseexponentially in this country. According to a studypublished in August by the Harvard School of PublicHealth in the American Journal of Clinical Nutrition,Americans' increased consumption of soda and

Looking for a unique way to show that you care? When you make an honor/memory gift in support ofthe DRI, you will conveniently:• Honor the accomplishments of friends, family,

and loved ones.• Celebrate birthdays, anniversaries, milestones,

or holidays.• Demonstrate your philanthropic support to business

associates and clients.• Keep the memory of your loved ones alive.When the DRI Foundation receives an honor ormemory gift, the individuals or family members inwhose name the contribution was made areimmediately notified, and in addition, you will receive aconfirmation from the DRI Foundation acknowledgingyour thoughtful and generous donation.

One of the easiest ways you can assistthe DRI in continuing its important work isto become a Workplace Ambassador. Simplyencourage your co-workers to contribute viayour workplace giving campaign! These giftsare tax deductible and can be made througha payroll deduction program.

For participants in the Combined FederalCampaign (CFC), please note that the DRI'snumber is 9505. We are also listed under theHealth 1st America's Charities Federation.

To learn more about how you can help,call 1-800-321-3437 or send an email toinfo@drif.org.

Honor a Loved One Through the DRIF

#9505

On August 17, 2006, President Bushsigned in to law, the highly anticipated PensionProtection Act of 2006.This legislation permitsindividuals over the age of 70 1/2 to make charitable gifts through their IRAs withoutincluding the amount of the gift as part of theirgross income.It doesn’t, however, provide acharitable income-tax deduction.

To qualify:• The donor must be past 70 1/2 years of age and own a traditional or Roth IRA.• The gift must be transferred directly fromthe IRA trustee to a qualified charity.If thefunds are withdrawn by the IRA owner andthen contributed to the charity, the amountwithdrawn will be included as part of thedonors gross income.• IRA gifts cannot exceed $100,000 peryear and can be made in 2006 and 2007.• Gifts cannot be made to charitableremainder trusts or other life income giftarrangements. Nor can they be made toprivate foundations, donor advised funds,or supporting organizations.To learn more about making a gift with

your IRA, please contact Jill Shapiro Miller, DRIFDirector of Gift Planning at 1-800-321-3437.

The Tax Free IRA Rolloveris Finally Here!

Jeffrey Young to Chair CPA Conference

Many of those connected to the Diabetes Research Institute and Foundation have come tothink of each other as members of an extended family. In times of sorrow, it's family that pulls usthrough, comforting our grief, refreshing fond memories and reminding us of happier days to come.It is with great sadness that the entire DRI family mourns the loss of Robert T. Held, Sr., whopassed away peacefully this past May at the age of 88. Though words cannot aptly honor him, we celebrate his life, his generosity, and his commitment to family.

Bob was one of the DRI's longtime champions and was involved with the organization since itsearliest days in the 1970s. In addition to bringing a number of opportunities to the organization andbeing involved with several fundraising events, Bob helped establish the first chair in the history ofthe University of Miami's Department of Medicine. In 1981, he endowed the Mary Lou Held Chairfor Diabetes Research, named for his daughter-in-law who has diabetes. He also served the DRIFoundation as Chairman of the Board of Governors, was a member of the Foundation’s Governors’Society, and later, the Honorary Board of Directors. Bob's philanthropic spirit seemed to know nobounds, and the DRI was only one of his many charitable interests.

The Held Family requested that contributions in Bob Held's memory help perpetuate his hope and efforts to find a cure for diabetes. To do so, please call 1-800-321-3437 or visitwww.diabetesresearch.org. Robert T. Held, Sr.

DRI Foundation Chief Financial Officer JeffreyYoung has been selected to chair the 2007 Florida CPA Not-for-Profit Organization Conference, an annualsymposium that takes place in Ft. Lauderdale andTampa in June, and is attended by more than 250certified public accountants from around the state. Heand his committee are charged with planning, directingand administering the conference in accordance withFlorida Institute of Certified Public Accountants (FICPA)policies and to comment on accounting, auditing andregulatory reporting requirements in the not-for-profit arena.

Adept in this particular realm of financial oversight,Jeff has also been appointed to the FICPA ExecutiveCommittee's Not-for-Proft task force, whose objectiveis to enhance the effectiveness of CPAs who serve

as employees or volunteers for non-profit organizations. The committee seeks to encourage and traincertified public accountants to serve on organizations' boards and create vehicles for non-profits tofind CPAs willing to serve and volunteer.

Since joining the Foundation in 1994, Jeff and his department have helped the Foundation'sfinancial operations run smoothly, particularly in light of the organization's tremendous growth. Thispast year, he and Oneida Osuna, accounting assistant, have processed almost 18,000 transactions, upfrom just over 6,000 in 1995. Nicole Washington has just joined his staff as data entry clerk, andwill be assisting with the growing responsibilities.

Before coming to the DRI, Jeff previously served as controller for an ophthalmic diagnosticscompany in Boca Raton. He is a certified public accountant in the State of Florida and a member of theAmerican Institute of CPAs. He recently published an article titled, “CA$H FLOW - Why Having GAAPIncome Doesn't Necessarily Mean You Can Pay Your Bills If You Are An NPO," in the March/April 2006issue of Florida CPA Today.

Jeffrey Young

In Memory of Robert T. Held, Sr.

13

On the eve of the Emmy Awards, another red carpet was rolledout for An Evening Under the Stars with Patti LaBelle, a lavish affairheld at the beachside home of Jill Viner and Cliff Viner to raisesupport and awareness for the DRI. Three hundred residents andguests of the Hamptons enjoyed the exclusive soiree in Quogue onSaturday, August 26. Miami-based event virtuoso Barton G. Weiss of Barton G. transformed the magnificent private residence into theultimate social scene and concert venue.

“We are all bestowed blessings,” the lovely LaBelle began,explaining her connection to the event's cause. “I have diabetes; it does not have me.”

LaBelle has lived with diabetes for more than a decade, andshe also lost her mother to complications of the disease. With passionin her voice, this performance was awe-inspiring. While standing on astage constructed atop the swimming pool, she sang favorites such asLady Marmalade, New Attitude, If Only You Knew, Over the Rainbow,and On My Own, among others. Although LaBelle's tearful balladsand upbeat dance tunes were one of the evening's highlights, it wasthe powerful words of the event’s hostess that truly took center stage.

“Three words led me here: My BrotherCraig,” said hostess Jill Viner, referring toCraig Silver, who has had type 1 diabetessince he was a child. She continued, “Theadvances at the Diabetes Research Institutehave been great, but we still need to helpDRI scientists find a cure.”

Jill then presented an award of appreci-ation to Barton G. “You are not only a life-time friend of mine, but also that of theDRI,” she said.

Barton G. Weiss of Barton G. providedfabulous décor and a creative menudesigned to be diabetes-friendly.

Craig and Sharon Silver, DRIF's Robert A. Pearlman, and Jill Viner posed withPatti LaBelle after her performance.

Robert A. Pearlman of the DRI Foundation took the stage, as well, to recognize the Viners and address the audience.

“Diabetes is growing at an epidemic proportion, but what wehave discovered through our research is that the disease can bereversed. In fact, two people with us today have undergone islet celltransplants and are now living insulin-free,” he said.

While eagerly awaiting LaBelle's arrival, guests received theultimate red carpet treatment. Welcoming doors swept open to greetguests with silver platters of wine. Intimate and flower bedeckedtables offered a cozy place to sit and talk, while savory food beckonedfrom every side of the exquisite back deck, all of which was surroundedby a breathtaking ocean view.

Specially formulated by Barton G. for a diabetes-consciousaudience, the menu was distinctly delicious. Protein-based “im-pasta”was made from chicken, shrimp and lobster. Seafood cocktails weremade to order with giant shrimp, lobster tails, king crab, blue craband a choice of sauces. Lamb chops, steak and chicken weregrilled to perfection upon request, and tuna, salmon and scallopswere dished out generously. The Nitro-tini Bar was busy all night,as peach, grapefruit and dirty martinis were served up with floatersof vodka frozen into cubes using liquid nitrogen. As the cubesmelted, the cocktails strengthened with each sip.

Not only was this event the debut for “nitrogen-fueled martinis,”but it also served as the unveiling of Barton G.'s new line of sugar-freedesserts. Including everything from double fudge brownies andcheesecake lollipops to an array of ice cream and sorbet, the dessertswere so seductively sweet that guests refused to believe they wereall sugar-free.

After pleasing their palates, lounging in the lap of luxury andexperiencing the intense performance of Patti LaBelle, guests departedvia the red carpet, feeling as ultra-fabulous as an Emmy Award winner.

REVELING IN THE RED CARPET TREATMENT

Hosts of the extravagant affair, Cliff and Jill Viner, paused for a family momentwith their daughters, Elyse (left center) and Amanda (right center).

LaBelle performed on a specially constructed stage over the pool.

14

BUILDING MILESTONES

International Union of Bricklayers and Allied CraftworkersExecutive Vice President Gerald O'Malley, right, presented JoeLinehan of Union Labor Life Insurance Company with the 2006Championship Trophy at the 6th Annual Building Trades SoftballSlam, held Saturday, August 26 at the National Labor College inSilver Spring, Maryland.

Motorcyclists prepared to depart at the IronworkersLocal 5 Poker Run in Maryland.

Members of the Parkersburg Marietta Building and Construction Trades Council AFL-CIO had a blast at their annual skeet shoot.

Celebrating a milestone anniversary, more than 30,000 members of theBuilding and Construction Trades Department put down their sheet metal, setaside their hammers, and held out their hard hats for a good cause. In hundredsof cities across all 50 states, they spent a day building bridges of a different sort,spanning the gap between those suffering with diabetes and the cure.

Since 1986, labor union workers, along with their families and friends, havebeen collecting donations for the DRI with their Dollars Against Diabetes (DAD'sDay) campaign. Officially recognized on the day before Father's Day, this longstanding tradition commemorated its 20th anniversary this year with collectiveproceeds surpassing the $19 million mark on June 17.

DAD's Day is the largest single-day fundraising campaign for diabetesresearch. Governors, senators and even US presidents have recognized the programas one of the top private sector initiatives in the United States. Aside from thetraditional street corner collections, the campaign has grown to include eventsfeaturing a wide variety of popular hobbies.

This year, more than 50 golf tournaments took place nationwide. Held byIBEW Local 26 and led by Business Manager Chuck Graham, the largest golftournament hosted 600 participants on five courses. Motorcycle enthusiasts ledby Jay Mummy of IBEW Local 153 and Steve Hardy of Ironworkers Local 5 achievedsuccess again with their Poker Runs. Thanks to the leadership of General

President John Flynn, the Bricklayers International 6th Annual Softball Slam raised more than$100,000. And Sam Davis and the Parkersburg-Marietta Building Trades held their 3rdAnnual DAD's Day Fun Shoot.

Along with an annual gin rummy and golf tournament called the Labor of Love, DAD'sDay is a cornerstone of Blueprint for Cure, an umbrella program of annual events spear-headed by the Building and Construction Trades Department and endorsed by the AmericanFederation of Labor-Congress of Industrial Organizations, commonly known as AFL-CIO.

This unique program began in 1984 when representatives from building trades metwith the DRI Foundation and learned from parents there about the need for a research andtreatment facility to lead the way toward a cure for diabetes. It reached a major milestonewhen the men and women of the unions funded and built the Diabetes Research Institutefacility in Miami, the most comprehensive diabetes research facility in the world. The buildingopened in 1994.Union workers have now raised more than $35 million to support the DRIand its research projects.

In recognition of the union's unparalleled support, a permanent plaque erected at the DRI's entrance bears the following statement:“Built by the hearts and hands of America's workers, whose generosity and craftsmanship knows no bounds.”To the thousands of people involved with DAD's Day and Blueprint for Cure today and throughout the past 20 years, the DRI extends its genuine

appreciation.The milestones we have reached together over the years are invaluable.

1515

EVENTSCOCKTAILS IN CONNECTICUT

Northeast

The fourth Northeast outreach cocktail reception was not only held fornew friends of the DRI, but also by one. Betsy Sorrel (center), whose16-year-old son, Robbie, has type 1 diabetes, hosted the intimate affairat her home in Greenwich on April 6. Many of the 60 guests were cur-rent members of Betsy's support group for parents of children with dia-betes. Hors d'oeuvres and cocktails were passed while the DRI's Dr. Norma S. Kenyon (left) discussed the latest scientific advancements indiabetes research. Then, Betsy, along with Erica Newman, spoke abouttheir experiences as mothers of children with diabetes. (Also pictured:DRIF's Robert A. Pearlman.)

FOUR HANDS, ONE CAUSE

On August 4, 19-year-old pianists and composers Jason Kram Yeager (2nd from right) and Ben Stepner presented Four Handsfor a Cure, a unique and original jazz performance followed by a wine and cheese reception, sponsored by M. Steinert & Sons.The duo performed 12 songs for a full-house at downtown Boston's Steinert Hall, adding nearly $5,000 to The Jason Fund,which Jason's grandparents, Elly (center) and Harvey Kram (far right), started after his diagnosis with type 1 diabetes sevenyears ago. The extraordinary 90-minute ensemble, including the works of leading musicians, as well as that of Jason and Benthemselves, drew a standing ovation. (Also pictured: Jason's parents Peter Yeager, Kathy Kram.)

16

Standing (l-r): Bruce Fishbein, The Produce Connection; Bruce Schumin, M & R Produce Distributors; ArthurHertz, Miami Seaquarium; Gary James, Southern Specialties; Don Strock; Jerry Share and Robert Piper, ShedsPlus; Chris Fries, The Produce Connection; and John Marini, Heineken USA. Sitting (l-r): Felix Hernandex,Coca-Cola; Rey Martinez, Crystal Springs; Doug Tannehill, C.H. Robinson Worldwide, Inc.; Terry Willie,Miccosukee Tribe of Indians of Florida; Joe Kettinger, Outback Steakhouse; and Sean White, MinutemanPress of Boca Raton. Not pictured: A-One-A Produce and Dairy, Six L's Packing Company, American Fruit &Produce Corp., Top Tomato Company, The Oppenheimer Group, Florida Mushroom, Freedom Fresh, SunkistGrowers, Sierra Produce, Dole, Riverside Fruit & Vegetables, Fresh Quest, Warren Henry Automobiles, Inc.,Bluestar Jets and Von Kantor Photography & Design.

17

UNCORKING THE CURE

TAKING HOME A HARLEYDuring the 34th annual Phil Peterson’s Key West Poker Run, sponsored by Peterson’s Harley-Davidson of Miami and Harley-Davidson South, motorcycle enthusiasts enjoyed a scenic trekfrom Miami to Key West along US 1. Key West’s famous Duval Streetwas closed to outsidetraffic for weekend revelers, who enjoyed the carnival-like atmosphere, live music, food anddrinks. Several activities kept visitors busy throughout the weekend of September 15-17,including a custom bike show,a hog roast, a bikini bike wash,plus contests judging wing-eating, beer guts and tattoos, and much, much more! Riders stopped at five designated locationsalong the way to draw what they hoped would be a winning poker hand. The players with thebest five hands won cash, and they, along with the players with the next five best hands,competed in a game ofTexas Hold ‘Em.The winner, Butch Knapp of Marathon, took home a brand new Harley Davidson Sportster! Pictured: Phil Peterson (dressed in white) celebratedanother successful Poker Run with his sons, Drew (left) and Dirk (far right), plus DRIF’s BrianHuether, who was happy to accept nearly $45,000 for the DRI.

Former Miami Dolphin quarterback and currenthead coach of the F.I.U. Golden Panthers DonStrock joined forces with the local produce industryfor the 23rd annual Don Strock Diabetes Classicheld at Miccosukee Golf & Country Club on May18. Presented by the Miami Seaquarium, thetournament is one of South Florida's longest run-ning celebrity/amateur charity golf tournaments.Past and present NFL players who joined Strockon the course this year included Bruce Hardy,Don McNeal, Nat Moore, Kerry Glenn, Uwe VonSchamann, Madre Hill, and Bob Brudzinski. Aftercocktails and dinner, an awards ceremony fol-lowed, during which 12-year-old Karen Ripoll andher mother, Teresa, spoke of a day in the life ofthe Ripoll family. Karen was diagnosed with type1 at age 7. The event raised an estimated$175,000, thanks to the committee's dedicationand the generosity of the sponsors (pictured).

PAR FOR 23

Florida

On October 14, the Key Biscayne Rotary Club sponsored the 2nd Annual Key BiscayneWine Tasting at the Sonesta Beach Resort. Guests sampled tastes from the world's finestwineries and nibbled on gourmet delicacies while mingling with the DRIF’s Robert A.Pearlman, Elina Linetsky of the DRI, islet transplant recipient Jon Hedrich, and Raul deMolina (AKA “El Gordo” of Spanish TV's “El Gordo y La Flaca”), among others. Pictured:Key Biscayne rotary club members (l-r) Angela O’Campo, Maggie and Ruben Weisson,President Bonnie Cooper, and Norm Roberts (far right) with the DRIF's Natasha Norris.

EVENTS

The 30th annual South Shore Sweethearts Tennis Tournament attracted more than 300tennis fans to Sportime at Atlantic Beach Tennis Club, during the week of July 8-16. Ledby Co-chairpersons Bob Zuckerman and Susan Miller, the event featured 14 divisions,including men's pro/am, women's round robin, and mixed doubles.Jerry (far left) andDavid Miller (left), winners of the first ever parent-child doubles contest, are pictured withthe competition, Brett Votano (right) and Steve Goldberg (far right).Raising more than$136,000, this anniversary event was as successful as ever.

SERVING UP 30 YEARS OF SUCCESS

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Held on May 4 at Jericho Terrace in Mineola, NY, Children's Best Hope for aCure featured silent and live auctions, cocktails, dinner, and a delightful programhighlighted by 13-year-old Lauren Bongiorno's rendition of “God Bless America.”Lauren's diagnosis with type 1 diabetes at age 7 gave her parents the motivationto start this fundraiser five years ago. This year, her father, Peter Bongiorno (farright), served as Honoree, while her mother, Michele Bongiorno, emceed. Theaffair's cumulative proceeds reached nearly $1.5 million thanks to the dedicationof several Long Island philanthropists, such as Co-chairs Maggie and Michael F.Greco (2nd from right), 2003 Honoree Steven J. Eisman (far left), 2002 HonoreeJames Ciocia (2nd from left), 2005 Honoree Carole Enisman (center), and 400generous attendees.

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The family of Helaine Shari White continues to celebrate her incredible love of lifeand powerful spirit with fundraising efforts that focus on laughter, fun and family.Her parents, Rhoda (third from left) and Donald White (far right), and her two sistersand brothers-in-law, Peter and Hillari Boritz (left with newborn daughter, Rebecca)and Renee and Ron Spiegel (middle back), organized the sixth annual Lanie'sLanes at the East Meadow Bowling Lanes on March 5. More than 100 peopleturned out, raising nearly $30,000 for the DRI.Also pictured are Sami, Brittneyand Marc Spiegel and Harrison Boritz.On May 7, Lanie's family participated in the 29th annual Five Boro Bike Tour, thelargest recreational cycling event in the U.S. The 42-mile, traffic-free ride throughthe streets, highways and bridges of New York City attracted 30,000 participants,but the White family organized its own group of 40 cyclists, who garnered pledgesfrom friends and family and rode in loving memory of Lanie. After the ride, thegroup enjoyed a celebratory picnic. The White, Boritz and Spiegel families wouldlike to offer special thanks to all the generous individuals and companies thatsupported their efforts, including AM SKIER, Elmwood Day Camp, Real DataManagement, and Custom Concentrates, among others.THANKS A MILLION

Boasting a hilarious line-up, including host Jim Turner andheadliner Dana Gould, with additional laughs supplied by GregBehrendt and Andy Kindler, Stand Up for a Cure will be held atThe Improv in Los Angeles on Sunday, November 12 at 5:30 p.m.Presented by Turner Construction Company, the fourth annualevent will feature sidesplitting comedic performances, plus acocktail reception, dinner, a live auction, and fantastic prizedrawings - from spa packages to awesome getaways. For ticketsand sponsorship opportunities, call the DRI Foundation’s LosAngeles office, 323-857-0080. For more information aboutthe event, visit www.standupforacure.org.

DEDICATED TO A FRIEND OF THE DRIOn August 7, Muttontown Country Club and Pine Hollow Country Club were sold out for the annual RodGilbert DRI Golf Classic in East Norwich, NY.With many New York Rangers' fans in attendance, Rod Gilbert'spresence was aptly appreciated, but a very special dedication gave the event even more meaning. Thetournament was held in memory of Anthony John Vitale, a friend of the DRI who had diabetes for 25years, and its proceeds were used to establish a grant in his name at the DRI. Members of the Vitale family,including Anthony J. Vitale, Jr. (right, shown with Gilbert), have been actively participating in this event for10 years. Their extra involvement this year garnered not only profits surpassing that of last year, but alsothe participation and support of family friend Senator Alfonso D'Amato. The event wrapped up with dinnerand an awards presentation, plus silent and live auctions, raising approximately $300,000.

What Not to Wearat Fall Into FashionUnsure of what not to wear?Find out at the ninth annual Fall Into Fashion luncheon, slated for10:30 a.m. on Thursday, December 7 at the Pine Hollow Country Club in East Norwich, NY, whereattendees might get an earful from one of TV's most prominent fashion mavens. Clinton Kelly,the always fashionably correct host of TLC's “What Not to Wear,” will appear at the event, wheresweepstake participants will have an exclusive opportunity to win a shopping experience with Kelly'sexpert styling advice and honest observations.The luncheon will also feature a sumptuous brunch, an exclusive shopping environment, and uniquedemonstrations - from cake decorating and coffee sampling to make-up application and massage.To join Co-chairs Miriam Shiff and Addy Fritzhand and Honorary Chairman Fran Helfant at the 2006event, purchase tickets online at www.diabetesresearch.org or call the DRI Foundation's Long Islandoffice at 516.621.8804 or email liregion@drif.org.

COMING UP : STAND UP!

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California

Don't miss a chance to shopwith Clinton Kelly at Lonny'sand Steven Dann of Great Neck.

1) Jim Turner; 2) Dana Gould; 3) Greg Behrendt; 4) Andy Kindler

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Stand Up For A CureNovember 12, 2006It will be another hilarious Night at the Improv when a host of colorful comedians take the stage for thisnewly renamed annual event.Circle of Champions Charity BrunchNovember 12, 2006Olympian Gary Hall, Jr. will host a Sunday brunch to beheld at South Beach's world famous Joe's Stone Crab,where the afternoon's honoree, former NBA center ChrisDudley, will be inducted into the Circle of Champions. DRI Harold Kart Golf ClassicNovember 13, 2006An afternoon of golf followed by a cocktail reception andawards dinner will take place at Boca West Country Club.Empire BallDecember 6, 2006New York's Real Estate Division will gather at theGrand Hyatt Hotel for this elegant, black-tie affair.Love and Hope Preview PartyDecember 7, 2006Often referred to as “the heart of Love and Hope,”this fabulous dinner reception will officially kick offthe group's fundraising season at the DiplomatCountry Club in Hallandale.Fall Into FashionDecember 7, 2006Set to the theme of “Friends Celebrating Friends,” thisfashionable brunch will be held at the Pine HollowCountry Club in East Norwich and feature a uniqueshopping experience, auctions, an appearance byTLC's Clinton Kelly, and more.Pleasures of the PalateJanuary 22, 2007To be held at NORMAN'S in Coral Gables, guests willenjoy a sumptuous five-course meal paired with winesfrom around the world, plus live and silent auctions. DRI Golf and Tennis ClassicJanuary 29, 2007An afternoon of golf and tennis tournaments at La Gorce Country Club in Miami Beach will be followed by a cocktail reception and awards dinner.

Palm Beach Auxiliary LuncheonFebruary 12, 2007This delightful luncheon, to be held at the Polo Clubin Boca Raton, will feature boutique shopping and acard party.Love and Hope Ball February 17, 2007To be held at the Westin Diplomat Resort & Spa inHollywood, this extraordinary affair is certain todelight and surprise its guests while commemorating33 years of success. Diabetes Research Institute WeekFebruary, 2007Volunteers will take to the streets during this weeklongevent to solicit contributions for the DRI. Studentswill conduct walkathons at Broward-area parks, andother fundraising projects are encouraged, such asdress down days, letter writing campaigns, and carwashes, among others. Carnival for a Cure March 11, 2007Enjoy games, fun foods, great activities and more atthis family-oriented afternoon event at theMetropolitan Pavilion. DRI Golf Classic April 23, 2007To be held at El Caballero Country Club, the thirdannual tournament will feature an afternoon of golf,followed by a dinner and awards ceremony.Crystal Ball May 7, 2007This black-tie gala at the Garden City Hotel will feature cocktails, dinner, dancing, auctions and live entertainment. Shell Key West Challenge May 17-21, 2007 For more than two decades, this five-day fishingtournament, sponsored by Shell Oil, has been a KeyWest tradition. For the first time, the 2007 eventwill benefit the DRI.

Diabetes Research Institute National Foundation Office3440 Hollywood Blvd.Suite 100Hollywood, FL 33021www.diabetesresearch.org

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CalendarFor information on the events or to make reservations,please call one of the DRI Foundation offices listed below. DRIfocus

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is a publication of the Diabetes Research Institute Foundation.Fall 2006 / Volume 35, Issue 1EditorLori Weintraub, APRContributorsLaurie CummingsCathryn Greene-ZavertnikNatasha NorrisLauren SchreierMitra Zehtab, M.D.DesignFranz Franc Design Group Inc.PhotographyFrancisco GonzalezMarc S. Levine PhotographyVon Kantor Photography & DesignClaude ZickFoundation Staff & VolunteersThe Diabetes Research Institute Foundation supports theDiabetes Research Institute at the University of Miami LeonardM. Miller School of Medicine, whose mission is to develop andrapidly apply the most promising research to treat and curethose now living with diabetes. To obtain additional informationor request copies of DRIfocus, please call (800) 321-3437 ore-mail lweintraub@drif.org, or visit www.diabetesresearch.org.

Diabetes Research Institute Foundation National Office3440 Hollywood Boulevard, Suite 100. Hollywood, FL 33021Phone: (954) 964-4040 Fax: (954) 964-7036info@drif.org

Northeast Regional Office381 Park Avenue South, Suite 1118, New York, NY 10016Phone: (212) 888-2217 Fax: (212) 888-2219 neregion@drif.org

Long Island Regional Office45 Glen Cove Road. Greenvale, NY 11548Phone: (516) 621-8804 Fax: (516) 621-8501liregion@drif.org

California Regional Office6624 Melrose Avenue. Los Angeles, CA 90038Phone: (323) 857-0080 Fax: (323) 857-1856caregion@drif.org