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Preparation of Methylcellulose Microcapsules Containing L-Glutamine
by Using Coalescence between Droplets in W/O Emulsion
Masato Tanaka*�, Yoshinari Taguchi* and Chieko Shima
Department of Science and Technology, Graduate School, Niigata University,
,�2*/* Ikarashi, Niigata-shi, Niigata 3/*�,+2+
* Department of Chemical Engineering, Niigata University,
,�2*/* Ikarashi, Niigata-shi, Niigata 3/*�,+2+
����������������
It was investigated whether methylcellulose microcapsules containing l-glutamine were able to be
prepared by using coalescence between two kinds of droplets in W/O emulsion or not. Methylcellulose as the shell
material was dissolved in the one aqueous droplets and the tannic acid as the gelation agent for methylcellulose
was dissolved in the other aqueous droplets. It was found that methylcellulose microcapsules were able to be
prepared by coalescence between the two kinds of droplets. The mean microcapsule diameter and the content rate
of l-glutamine were found to increase with the concentration of methylcellulose. Moreover, it was found that
microcapsules were not destroyed in the water phase and l-glutamine was released through the ungelated part of
the microcapsule shell. (Received May ,, ,**/ ; Accepted Jun. +0, ,**/)
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�/º ®Corresponding author`� tanaka@eng.niigata-u.ac.jp
Nippon Shokuhin Kagaku Kogaku Kaishi Vol. /,, No. 3, .*0 .++ (,**/) »01¼406 ® 22 `
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Fig. + Schematic diagram of experimental apparatus
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Table + Experimental conditions
²Experimental Conditions³volume of continuous phase
volume of dispersed phase
amount of lecithin
volume of gelation agent solution
concentration of gelation agent
impeller speed
reaction temperature
reaction time
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