vascular access in cardiac catheterization

Post on 07-May-2015

2.185 Views

Category:

Health & Medicine

5 Downloads

Preview:

Click to see full reader

DESCRIPTION

SITE COMPLICATIONS ADVANTAGES DIS-ADVANTAGES COMPARISON HEMOSTASIS

TRANSCRIPT

Vascular Access during Cardiac Catheterization

VASCULAR ACCESS,COMPLICATIONS,MERITS

1

Dr Vikash M,DM(SR).NIMS,Hyderabad,Indiavikasmedep@yahoo.co.in

VASCULAR ACCESS,COMPLICATIONS,MERITS2

Profile

VASCULAR ACCESS

ARTERIAL VENOUS

VASCULAR ACCESS,COMPLICATIONS,MERITS

3

Retrograde/antegrade.

ARTERIAL

FEMORAL RADIAL BRACHIAL ULNAR

VASCULAR ACCESS,COMPLICATIONS,MERITS

4

Venous Accesss

VENOUS

FEMORAL IJV SUBCLAVIAN

VASCULAR ACCESS,COMPLICATIONS,MERITS

5

TOPIC OVERLAY

• SITE

• COMPLICATIONS

• ADVANTAGES

• DIS-ADVANTAGES

• COMPARISON

• HEMOSTASIS

VASCULAR ACCESS,COMPLICATIONS,MERITS6

FEMORAL ACCESS - ANATOMY

VASCULAR ACCESS,COMPLICATIONS,MERITS7

ARTERIAL ACCESS

• FEMORAL ARTERIAL ACCESS

• Most commonly used access for PCI

• SITE OF PUNCTURE

• Common femoral artery

• 2 cm below the inguinal ligament.

• Inguinal ligament runs from the anterior superior iliac spine to the pubic tubercle

VASCULAR ACCESS,COMPLICATIONS,MERITS8

• Some operators rely on the location of the inguinal skin crease to position the skin nicks

• The position of the skin crease itself can be misleading in obese patients

• Localization of the skin nick by fluoroscopy

• Should show the nick to overlie the inferior border of the femoral head

VASCULAR ACCESS,COMPLICATIONS,MERITS9

COMPLICATIONS

• VASCULAR

• Hematoma

• Pseudo-aneurysm

• A-V fistula

• Retropertonial hemorrhage

• Thrombosis

• NON VASCULAR

• Infections

VASCULAR ACCESS,COMPLICATIONS,MERITS10

VASCULAR ACCESS,COMPLICATIONS,MERITS11Nasser TK, Mohler ER 3rd, Wilensky RL, Hathaway DR. Peripheralvascular complications following coronary interventional procedures.Clin Cardiol.1995;18:609–614.

PROCEDURAL RISK STRATIFICATION• Low Risk:(<1% Complication Rate)

• Diagnostic Angiographic Procedures

• Moderate Risk: (1% to 3% Complication Rate)

• Routine Percutaneous Intervention

• High Risk (>3% Complication Rate)

• Primary PCI for acute MI, prolonged multivessel PCI , or procedures that require larger sheath sizes (eg,>8F)

VASCULAR ACCESS,COMPLICATIONS,MERITS13

RISK FACTORS

• Modifiable

• Site of puncture

• Number of attempts

• Size of sheath

• Sheath removal

• Medications

• Non modifiable

• Age

• Gender

• BMI

• Associated disorders - CKD

VASCULAR ACCESS,COMPLICATIONS,MERITS14

COMPLICATIONS

VASCULAR ACCESS,COMPLICATIONS,MERITS15

• NUMBER OF ATTEMPTS

• Best – 1 attempt

• Better – 2 attempts

• Complications - > 2 attempts

• Shift to other side / site.

• SHEATH SIZE

• Greater the size more chances of complications

• Grossman and colleagues found that PCIs performed with 7F and 8F sheath compared with 6F were associated with more vascular compliactions

VASCULAR ACCESS,COMPLICATIONS,MERITS16

• SHEATH REMOVAL• Time

• Compression

• Adequate compression just proximal to the site of skin puncture for at least 30 min is ideal.

• MEDICATIONS• Anti platelets – oral , IV

• Anti coagulants.

VASCULAR ACCESS,COMPLICATIONS,MERITS17

NON-MODIFIABLE

• AGE – elderly > younger

• SEX – female > male.

• BMI – high > low > normal

• # Delhaye et al – 6% high, 5.1% low, 2.0% normal

• # Delhaye C, Wakabayashi K, Maluenda G, et al. Body mass index and bleeding complications after percutaneous coronary ,AmHeart J.2010;159:1139-1146.

VASCULAR ACCESS,COMPLICATIONS,MERITS18

• ASSOCIATED CONDITIONS

• HYPERTENSION.• Manoukian et al, patients with a higher systolic

BP (140 vs 120 mm Hg;P= .02) were significantly more likely to have complications than were patients with lower blood pressures *

• CKD

• *Manoukian SV, Feit F, Mehran R, et al. Impact of major bleeding on 30-day mortality and clinical outcomes in patients with acute coronary syndromes: an analysis from the ACUITY Trial. J Am Coll Cardiol.2007;49:1362-1368

VASCULAR ACCESS,COMPLICATIONS,MERITS19

• HEMATOMA

• Definition

• Collection of blood in the soft tissue

• Incidence

• Most common vascular complication

• 5- 20 %

• Clinical features

• Pain, swelling, indurationVASCULAR ACCESS,COMPLICATIONS,MERITS20

VASCULAR ACCESS,COMPLICATIONS,MERITS21

VASCULAR ACCESS,COMPLICATIONS,MERITS22

VASCULAR ACCESS,COMPLICATIONS,MERITS23

Rao SV, O'Grady K,. Impact of bleeding severity on clinical outcomes among patients with acute coronary syndromes. Am J

Cardiol. 2005;96:1200–1206

PSEUDO-ANEURYSM

• Definition

• A contained rupture; with disruption of all 3 layers of the arterial wall.

• Occur when an arterial puncture site does not adequately seal.

• Pulsatile blood tracks into the perivascular space and is contained by the perivascular structures, which then take on the appearance of a sac.

  VASCULAR ACCESS,COMPLICATIONS,MERITS24

VASCULAR ACCESS,COMPLICATIONS,MERITS25

• One of the common vascular complications of cardiac and peripheral angiographic procedures.

• The incidence after diagnostic catheterization ranges from 0.05% to 2%.

• When coronary or peripheral intervention is performed, the incidence increases to 2% to 6%.*

• *Hessel SJ, Adams DF, Abrams HL. Complications of angiography. Radiology. 1981; 138: 273–281.

VASCULAR ACCESS,COMPLICATIONS,MERITS26

VASCULAR ACCESS,COMPLICATIONS,MERITS27

• DIAGNOSIS

• CLINICAL

• Pain and swelling at puncture site.

• Swelling from a large aneurysm may also lead to compression of nerves and vessels with associated neuropathy, venous thrombosis, claudication, or, rarely, critical limb ischemia.

• Local ischemia of the skin may lead to necrosis and infection.

• On physical examination, there may be a palpable pulsatile mass or the presence of a bruit.

VASCULAR ACCESS,COMPLICATIONS,MERITS28

• However, it should be noted that none of these physical findings may be present.

• Pain that is disproportionate to that expected after a PCI should undergo an doppler to exclude pseudoaneurysm regardless of the presence of a bruit.

VASCULAR ACCESS,COMPLICATIONS,MERITS29

• IMAGING

• Duplex ultrasound

• The sensitivity is 94% with a specificity of 97%.

• Echolucent sac that expands and contracts with cardiac contraction .

• On color Doppler, there is a swirling flow pattern with turbulence in the chamber(s), there may be 1 or more chambers.

• A tract connects the chamber to the feeding vessel.

• When a pulsed wave Doppler is placed within the track, a “to-and-fro” signal is obtained

VASCULAR ACCESS,COMPLICATIONS,MERITS30

VASCULAR ACCESS,COMPLICATIONS,MERITS31

• TREATMENT

• Until the early 1990s, the only treatment available was surgery.

• Since that time, USG compression, USG guided thrombin injection, FemStop compression devices, coil insertion, fibrin, adhesives, or balloon occlusion have been used with variable success.

VASCULAR ACCESS,COMPLICATIONS,MERITS32

• USG guided compression

• In 1991, Fellmeth and associates introduced a safe and noninvasive method to treat PSA.

• Success rate of 75% to 98%.

• The ultrasound transducer is positioned and pressure is applied to compress the chamber and tract while flow in the native artery is allowed.

• Direct ultrasound visualization confirms cessation of flow.

• Compression is usually held for cycles of 10 minutesVASCULAR ACCESS,COMPLICATIONS,MERITS33

• The vertical angle created by the device does not allow selective compression of the chamber and tract.

• Nonselective compression leads to longer compression times, more discomfort to the patient, and a lower success rate, in addition to an increase in complications such as DVT

• Body habitus, size, depth, and number of chambers, as well as concurrent anticoagulation may limit the success

VASCULAR ACCESS,COMPLICATIONS,MERITS34

• In patients on anticoagulation, the success is 30% to 73%.

• In 100 cases of pseudoaneurysm, was successful in 94 patients (94%), which included 30 (86%) of 35 patients who received anticoagulation and 64 (98%) of 65 patients who were not on anticoagulation.*

• Katzenschlager R, Ugurluoglu A,. Incidence of pseudoaneurysm after diagnostic and therapeutic angiography.Radiology. 1995;195:463–466

VASCULAR ACCESS,COMPLICATIONS,MERITS35

• DISADVANTAGES

• Long time - average compression time to achieve occlusion was 33 min with a range of 10 to 120 min*

• Painful

• Position

• Operator

• *Cox GS, Young JR, Gray BR, Grubb MW, Hertzer NR. Ultrasound-guided compression repair of postcatheterization pseudoaneurysms:results of treatment in one hundred cases.J Vasc Surg. 1994;19:683–686

• COMPLICATIONS

• Vasovagal reactions,

• Rupture,

• Skin necrosis, and

• DVT

VASCULAR ACCESS,COMPLICATIONS,MERITS36

• Ultrasound-Guided Thrombin Injection

• The principle - thrombin is important in the conversion of fibrinogen to fibrin.

• Thus a fibrin clot is formed instantaneously (even in the presence of antiplatelet therapy or anticoagulation therapy.

• Success ranges from 91% to 100%*

• *Cope C, Zeit R. Coagulation of aneurysms by direct percutaneous thrombin injection. Am J Roentgenol. 1986;147:383–387.

VASCULAR ACCESS,COMPLICATIONS,MERITS37

• Complications

• DVT (if the thrombin is inadvertently injected into the vein),

• Pulmonary embolism

• Thrombosis of the artery.

• Allergic reactions and anaphylaxis.

• PARA ANEURYSMAL SALINE INJECTION

VASCULAR ACCESS,COMPLICATIONS,MERITS38

VASCULAR ACCESS,COMPLICATIONS,MERITS39

---

---

• ENDOLUMINAL MANAGEMET

• serves to exclude a pseudoaneurysm from the circulation

• Depends on the size of the pseudoaneurysmal neck and the expendability of the donor artery .

• 2 broad categories: embolization and stent

• The width of the neck relative to the diameter of the donor artery is the determining factor.

• A vital donor artery may be embolized in certain emergent situations (eg, rupture with active bleeding); however, distal blood flow must then be restored by means of a surgical bypass procedure

VASCULAR ACCESS,COMPLICATIONS,MERITS40

• COIL CLOSURE

• If the neck is narrow,

• made of either stainless steel or platinum.

• Polyester fibers are incorporated the coil to increase its thrombogenicity

• Disadvantage

• Potential for recanalization.

• COVERED STENT

• Indications Large neck & larger artery

• Contraindication – mycotic aneurysm

VASCULAR ACCESS,COMPLICATIONS,MERITS41

SURGERY

VASCULAR ACCESS,COMPLICATIONS,MERITS42

• Disadvantages of surgery

• Requires anesthesia

• An incision usually in the groin, an area known to become infected easily after a surgical procedure.

• Lumsden and colleagues reported a surgical complication rate of 20% repair.

• Complications included bleeding, infection, neuralgia, prolonged hospital stay

VASCULAR ACCESS,COMPLICATIONS,MERITS43

• Prevention

• More complex procedures and more potent antithrombotic therapy have led to the occurrence of more frequent aneurysm formation.

• The most important strategies to prevent formation are:

• ● Assure a needle puncture in the proper location achieve vascular access on the first puncture without access through the posterior wall.

• ● Appropriate groin compression after sheath removal.

VASCULAR ACCESS,COMPLICATIONS,MERITS44

RETRO-PERITONEAL HEMATOMA

VASCULAR ACCESS,COMPLICATIONS,MERITS45

RETROPERITONEAL HEMATOMA

• Incidence

• 0.1 – 0.2 %

• CAUSES

• High puncture

• Inadvertent puncture of the posterior wall of the femoral or iliac artery

• Exacerbated by the fact that patients receive antiplatelets, anticoagulants

• Removal of catheter without wireVASCULAR ACCESS,COMPLICATIONS,MERITS46

• Retroperitoneal Hematoma After Percutaneous Coronary Intervention: Prevalence, Risk Factors, Management, Outcomes, and Predictors of Mortality

• Volume 3, Issue 8, August 2010

VASCULAR ACCESS,COMPLICATIONS,MERITS47Retroperitoneal Hematoma After Percutaneous Coronary Intervention: Prevalence, Risk Factors, Management, Outcomes, and Predictors of MortalityVolume 3, Issue 8, August 2010 , JACC

• CLINICAL FEATURES

• High index of suspicion

• Very subtle clinical signs of haemorrhage

• Back, lower abdominal or groin discomfort and swelling,

• Pallor, sweating.

• Relative hypotension and mild tachycardia that transiently improves with administration of fluids

• Unable to mount tachycardia because of beta-blockers, and these patients usually become hypotensive with no change in their heart rate

VASCULAR ACCESS,COMPLICATIONS,MERITS49

• Retroperitoneal haematoma near or within the iliopsoas muscle presents as femoral neuropathy, begins with groin pain or leg weakness

• Sudden onset severe pain in the affected groin and hip

• Iliopsoas spasm often results in the flexion and external rotation of the hip, attempt to extend the hip results in severe pain.

VASCULAR ACCESS,COMPLICATIONS,MERITS50

• DIAGNOSIS

• CBP – fall in Hb

• IMAGING

• Ultrasonography of the abdomen and pelvis may detect haematoma,.

• Limited by patient's discomfort, body habitus, underlying bowel gas .

• Free fluid or blood in the retroperitoneum pass into the abdominal or pelvic cavity

VASCULAR ACCESS,COMPLICATIONS,MERITS51

• CT SCAN

• Type, site and extent of the fluid collections.

• Active bleeding can be seen as extravasation of contrast material,

• CT angiography may show the site of the bleed and contrast outside the vessels.

• MRI

• Useful in patients presenting with femoral neuropathy, as MRI helps to rule out nerve root compression or spinal problems.

• Shows the site of the bleed.

• ANGIOGRAPHY

• Haemodynamically unstable, view to selective embolisation or placement of a stent graft is indicated

VASCULAR ACCESS,COMPLICATIONS,MERITS52

• MANAGEMENT

• Fluid resuscitation, blood transfusion and normalisation of coagulation factor.

• No specific guidelines to suggest when to intervene with endovascular or open surgery to stop the bleeding.

• If the patient is haemodynamically stable with no evidence of on-going bleeding, conservative management is recommended.

VASCULAR ACCESS,COMPLICATIONS,MERITS53

• ENDOVASCULAR TREATMENT

• Indications - Panetta et al*

• Hemodynamic instablitiy

• Hemodynamiclly stable- four or more units of blood transfusion within 24 h, or six or more units within 48 h

• Selective intra-arterial embolisation

• Stent-grafts

• Very few heterogeneous case series on stent-grafts in the management of retroperitoneal haematoma

• * Panetta T, Sclafani SJ, Goldstein AS et al. Percutaneous transcatheter embolization for massive bleeding from pelvic fractures. J Trauma 1985; 25: 1021-9

VASCULAR ACCESS,COMPLICATIONS,MERITS54

• OPEN SURGERY

• Indications

• Unstable despite adequate fluid and blood product resuscitation,

• Failed embloization / stent

• Abdominal compartment syndrome

VASCULAR ACCESS,COMPLICATIONS,MERITS55

A-V FISTULA

VASCULAR ACCESS,COMPLICATIONS,MERITS56

• DEFINITION

• Abnormal connections between the arterial and venous system that bypass the normal anatomic capillary beds

• RISK FACTORS

• Female Hypertension

• Anticoagulation , Low or multiple punctures

• Obesity Advanced age.

VASCULAR ACCESS,COMPLICATIONS,MERITS57

• Low groin puncture –

• Likely to access SFA just distal to the CFA bifurcation.

• The profunda femoris vein passes between the SFA and the profunda femoris artery

• Punctures to the proximal SFA are particularly vulnerable to causing AVF because the needle tip frequently punctures the underlying profunda vein.

• Sheath placement –

• Dilation of the tract between an artery and vein reduces the likelihood that the communication will close.

• The larger the sheath size, the greater the risk for AVF

VASCULAR ACCESS,COMPLICATIONS,MERITS58

• INCIDENCE

• 0.I to 1 %*

• CLINICAL FEATURES

• Initially silent.

• Two days to several months

• Abnormal sensation in the groin, fatigue, new onset or worsened lower extremity ischemia.

• *Glaser RL, McKellar D, Scher KS. Arteriovenous fistulas after cardiac catheterization. Arch Surg 1989; 124:1313. VASCULAR ACCESS,COMPLICATIONS,MERITS59

• Palpation and auscultation of the affected vessel demonstrates a machinery-like murmur, bruit, hematoma or pulsatile mass.

• The patient may exhibit lower extremity edema

• CONSEQUENCES

• DVT, nerve compression and new onset or worsened varicose veins

• The most significant condition related to AVF is high-output heart failure

VASCULAR ACCESS,COMPLICATIONS,MERITS60

• DIAGNOSIS

• Duplex ultrasonography 

• Current diagnostic test of choice

• High frequency, low resistance flow

• is typical ,with a mosaic color pattern.

• Often the specific artery and vein involved can be identified

• CT ANGIO

• Picks up the defect

• CONVENTIONAL ANGIO

• Appears as a blush with rapid filling of the adjacent deep vein

VASCULAR ACCESS,COMPLICATIONS,MERITS61

• TREATMENT  

• Most small asymptomatic AVFs thrombose spontaneously and thus should be observed

• INDICATIONS:

• Clinical symptoms related to the AVF

• Steal syndrome causing claudication or distal limb ischemia

• Significant edema or venous insufficiency due to venous hypertension

• Heart failure due to a high-flow fistula

• Progressive enlargement under ultrasound surveillance

• Iatrogenic AVFs that do not seal spontaneouslyVASCULAR ACCESS,COMPLICATIONS,MERITS62

• Ultrasound-guided compression

• Compression of sufficient force to abolish flow through the fistula without unduly reducing distal perfusion

• Painful

• Failure is frequent because the fistula track is too short or the AV fistula is too large

• Chronic AVFs (>2 to 3 weeks) rarely respond to compression.

• Ongoing anticoagulation also decreases success rates of UGC.

• Endovascular repair

• Covered stent placement or embolization techniques

• Surgery VASCULAR ACCESS,COMPLICATIONS,MERITS63

VASCULAR ACCESS,COMPLICATIONS,MERITS64

VASCULAR ACCESS,COMPLICATIONS,MERITS65

• Incidence

• 0.5 – 1%

• Diagnosis

• Doppler studies

• Peripheral angiogram

• Treatment

• Small – spontaneous lysis

• Large, limb threatening – thrombolysis / thrombectomy

VASCULAR ACCESS,COMPLICATIONS,MERITS66

• INFECTIONS

• Incidence <1%,

• Bacterial infections occurred in 0.11% at a median of 1.7 days after the procedure*

• CLINICAL FEATURES

• Pain, erythema, swelling at puncture site

• Purulent discharge

• Fever

• *Munoz P, Blanco JR, Rdoriguez-Creixems M, et al. Blood stream infections after invasive nonsurgical cardiology procedures. Arch Intern Med 2001;161:2110–2115

VASCULAR ACCESS,COMPLICATIONS,MERITS67

• Causes

• Improper shaving

• Improper scrubbing

• TREATMENT

• Antibiotics

• PREVENTION

• Appropriate shaving / scrubbing.

• Using sterile drapes.

VASCULAR ACCESS,COMPLICATIONS,MERITS68

• FEMORAL NEUROPATHY

• Incidence

• 0.1 – 0.3%

• Mechanism

• Compression of the femoral nerve during puncture or by hematoma

• Clinical features

• Tingling, numbness, weakness,

• Treatment

• Usually self remitting VASCULAR ACCESS,COMPLICATIONS,MERITS69

RADIAL ACCESS

VASCULAR ACCESS,COMPLICATIONS,MERITS70

VASCULAR ACCESS,COMPLICATIONS,MERITS71

VASCULAR ACCESS,COMPLICATIONS,MERITS72

PRE -REQUISITES

VASCULAR ACCESS,COMPLICATIONS,MERITS73

• Diagnostic Accuracy

• Ruengsakulrach et al.compared the Modified Allen’s Test with Doppler and found the Modified Allen’s Test to have a sensitivity of 100% and specificity of 97%.

• Glavin and Jones compared the Modified Allen’s Test with Doppler a sensitivity of 87% to correctly diagnose the presence of ulnar artery blood flow and a negative predictive value of only 0.18; i.e., 80% of all abnormal Modified Allen’s Test results in their study were incorrect.

• The diagnostic accuracy of the Modified Allen’s Test, compared with ultrasound, was only 80%, with a sensitivity of 76% and a specificity of 82%

VASCULAR ACCESS,COMPLICATIONS,MERITS74

BARBEAU TEST

VASCULAR ACCESS,COMPLICATIONS,MERITS75

COMPLICATIONS

VASCULAR ACCESS,COMPLICATIONS,MERITS76

• COMPLICATIONS• PROCEDURAL • Vaso vagal reaction• Spasm• Perforation / Dissection.• POST PROCEDURE• Occlusion• Compartment Syndrome • Pseudoaneurysm•

VASCULAR ACCESS,COMPLICATIONS,MERITS77

• VASOVAGAL REACTIONS

• Due to pain, anxiety

• PREVENTION

• Preprocedural sedation, analgesia, and adequate local infiltration anesthesia decreases pain, anxiety, and associated vagal output

VASCULAR ACCESS,COMPLICATIONS,MERITS78

• SPASM• Induced by the introduction of a sheath or catheter • Mechanism

• Prominent medial layer that is largely dominated by alpha-1 receptors.

• Increased levels of catecholamines cause spasm

• Risk factors

• Female young age small artery

• Anxiety Unsuccessful guide wire passage

• Multiple catheter exchanges, prolonged procedure

VASCULAR ACCESS,COMPLICATIONS,MERITS79

• Prevention

• Adequate vasodilatory cocktail containing

• NTG 100 – 200 mcg + 2.5 mg verapamil, + 40 U/Kg heparin max 5000 u

• Hydrophilic catheters

• Smaller sheaths

• TREATMENT

• Additional doses of CCB, NTG,

• More analgesia / sedation

• Warm compressVASCULAR ACCESS,COMPLICATIONS,MERITS80

• HEMATOMA

• Rare , Easily compressed against bone

• Grades of hematoma *

• <5 cm (grade I),

• <10 cm (grade II),

• Distal to the elbow (grade III), and

• Proximal to elbow (grade IV).

• Hematomas grade III and IV are not directly related to the puncture site, but result from wire damage to vessels and small perforations

• Hamon M, Rasmussen LH, Manoukian SV, et al. Choice of arterial access site and outcomes in patients with acute coronary syndromes managed with an early invasive strategy: The ACUITY trial. EuroIntervention 2009;5:115–120VASCULAR ACCESS,COMPLICATIONS,MERITS81

• COMPARTMENT SYNDROME

• Limb threatening condition

• Foremarm hematoma compressing the ulnar & radial artery – ischemia.

• incidence of 0.4%*

• *Tizon-Marcos H, Barbeau GR. Incidence of compartment syndrome of the arm in a large series of transradial approach. J Interv Cardiol. 2008;21:380-384

VASCULAR ACCESS,COMPLICATIONS,MERITS82

• Causes

• Unrecognized perforation at a distance from the puncture site,

• Unsuccessful compression at the puncture site, or

• Radial artery laceration induced at sheath insertion

• Prevention

• Early recognition and management of hematoma

• Treatment

• Surgical decompression.

VASCULAR ACCESS,COMPLICATIONS,MERITS83

• AVULSION• A sheath entrapped by arterial spasm should never be

forcibly removed because traumatic eversion radial artery may result.

• Prevention• Repeat intra-arterial vasodilators,

• Additional patient sedation and/or analgesia, and

• Reinsertion of the introducer and guidewire may be necessary.

• In refractory cases, axillary nerve blocks or general anesthesia may be required for catheter removal

VASCULAR ACCESS,COMPLICATIONS,MERITS84

• DISSECTION / PERFORATION

• Angiography of the arm should be performed if there is difficulty with wire or catheter advancement since failure to identify the problem may lead to vessel perforation or dissection.

• Rather than aborting the procedure, it is worth trying to carefully re-cross them with a soft 0.014 angioplasty wire.

• If this attempt is successful, the catheter will usually seal the dissection or perforation, an

• Aborting the procedure will leave an unsealed dissection or perforation that may be difficult to control

VASCULAR ACCESS,COMPLICATIONS,MERITS85

• RADIAL ARTERY OCCLUSION• Incidence

• 2% to 10% of patients*

• Risk factors**

• Lack of Heparin therapy

• Large artery-catheter mismatch,

• Female sex,

• Lack of pretreatment with clopidogrel,

• Diabetes, and

• Occlusive hemostasis

• Wu CJ, Lo PH, Chang KC, et al. * Transradial coronary angiography and angioplasty. Cathet Cardiovasc Diagn. 1997;40:159-163.

• **Stella PR, Kiemeneij F, Laarman GJ, Odekerken D,. Incidence and outcome of radial artery occlusion following transradial artery coronary angioplasty.Cathet Cardiovasc Diagn 2007;40:156–158

VASCULAR ACCESS,COMPLICATIONS,MERITS86

• Consequences

• Usually benign and asymptomatic due to the dual blood supply to the hand

• Hand ischemia, gangrene

• Spontaneous recanalizaton appears to occur in 50% of patients

• Prevention

• Pre-procedural heparin > 5000u, without heparin 60-70%, with 2-6%*

• Immediate sheath removal

• Vascular devices better than manual compression.

• *Spaulding C, Lefevre T, Funck F, et al. Left radial approach for coronary angiography: results of a prospective study. Cathet Cardiovasc Diagn. 2010;39:365-370.

VASCULAR ACCESS,COMPLICATIONS,MERITS87

VASCULAR ACCESS,COMPLICATIONS,MERITS88

VASCULAR ACCESS,COMPLICATIONS,MERITS90

VASCULAR ACCESS,COMPLICATIONS,MERITS91

VASCULAR ACCESS,COMPLICATIONS,MERITS92

VASCULAR ACCESS,COMPLICATIONS,MERITS93

VASCULAR ACCESS,COMPLICATIONS,MERITS94

VASCULAR ACCESS,COMPLICATIONS,MERITS95

2011 ACCF/AHA/SCAI/ESC Guideline for Percutaneous Coronary Intervention Class IIa1. The use of radial artery access can be useful todecrease access site complications.

• CONDITIONS WHERE READIAL ACCESS SHOULD BE PREFERRED

• Absent femoral pulses

• Femoral bruit

• Femoral artery graft surgery

• Extensive inguinal scarring from past surgery

• Surgery / radiation treatment near inguinal area

• Extensively tortuous iliac system / lower abdominal aorta

• Abdominal aortic aneurysm

• Patient request

• CONDITIONS WHERE READIAL ACCESS SHOULD BE AVOIDED

• Radial artery being considered for CABG / AV fistula

• Upper limb atherosclerosis, extreme tortuosity, Raynaud’s or Burger’s disease.

• Need for 7F or larger sheath.

VASCULAR ACCESS,COMPLICATIONS,MERITS96

FEMORAL vs RADIAL APPROACH

VASCULAR ACCESS,COMPLICATIONS,MERITS97

VASCULAR ACCESS,COMPLICATIONS,MERITS98

VASCULAR ACCESS,COMPLICATIONS,MERITS99

VASCULAR ACCESS,COMPLICATIONS,MERITS100

VASCULAR ACCESS,COMPLICATIONS,MERITS101

VASCULAR ACCESS,COMPLICATIONS,MERITS102

VASCULAR ACCESS,COMPLICATIONS,MERITS103

VASCULAR ACCESS,COMPLICATIONS,MERITS104

Primary and Secondary Outcomes

Radial(n=3507)

%

Femoral (n=3514)

%HRHR 95% CI95% CI PP

Primary Outcome

Death, MI, Stroke, Major Bleed 3.7 4.0 0.920.92 0.72-1.170.72-1.17 0.500.50

Secondary Outcomes

Death, MI, Stroke 3.2 3.2 0.980.98 0.77-1.280.77-1.28 0.900.90

Major Bleeding 0.7 0.9 0.730.73 0.43-1.230.43-1.23 0.230.23

VASCULAR ACCESS,COMPLICATIONS,MERITS105

Other Outcomes Radial(n=3507)

Femoral (n=3514)

P P

Access site Cross-over (%) 7.6 2.0 <0.0001<0.0001

PCI Procedure duration (min) 35 34 0.620.62

Fluoroscopy time (min) 9.3 8.0 <0.0001<0.0001

Persistent pain at access site >2 weeks (%) 2.6 3.1 0.220.22

Patient prefers assigned access site for next procedure (%)

90 49 <0.0001<0.0001

VASCULAR ACCESS,COMPLICATIONS,MERITS106

VASCULAR ACCESS,COMPLICATIONS,MERITS107

BRACHIAL ARTERY ACCESS

• SITE OF PUNCTURE

• Medial aspect of cubital fossa, 2-3 cm above the elbow crease

• INDICATIONS

• Renal / lower limb artery angioplasty

• COMPLICATIONS

• Hematoma

VASCULAR ACCESS,COMPLICATIONS,MERITS109

• Hand ischemia

• Due to thrombosis

• Compartment syndrome

• Hematoma extends into forearm

• Median nerve injury

•  0.2 and 1.4%

• Orator’s hand posture

• ACCESS trial – radial vs brachial access

• More complications with brachial approach ( 0.2% vs 2.6% p 0.03 )

VASCULAR ACCESS,COMPLICATIONS,MERITS110

VASCULAR ACCESS,COMPLICATIONS,MERITS111

ULNAR ARTERY ACCESS• SITE

• 2-3 cm above the crease of wrist

• ADVANTAGES

• Preservation of radial artery for CABG

• PREREQUISITE

• Reverse Allen’s test

• COMPLICATIOS

• Same as with radial artery access

• EVIDENCE – PCVI-CUBA trial radial vs ulnar

• Success rate - access 96% vs 93%, PCI – 96% vs 95%,

complication rate 1% vs 1.2 % .

VASCULAR ACCESS,COMPLICATIONS,MERITS112

HEMOSTASIS

• MANUAL COMPRESSION

• MECHANICAL COMPRESSION

• TOPICAL HEMOSTATIC AIDS

• VASCULAR CLOSURE DEVICES

1. Active

2. Passive .

VASCULAR ACCESS,COMPLICATIONS,MERITS113

• MANUAL COMPRESSION

• Remains the “gold standard”

• Timing

• Diagnostic procedure - Immediately

• Interventions - 4-6 hrs, ACT < 170 sec

• Site

• 2 cm proximal to skin puncture site

• Duration

• 15 – 30 min, larger sheath, longer time

• 3-4 min compression / french.

• Dis advantage

• Ineffective compression due to fatigue

VASCULAR ACCESS,COMPLICATIONS,MERITS114

VASCULAR ACCESS,COMPLICATIONS,MERITS115

FEM-STOP

VASCULAR ACCESS,COMPLICATIONS,MERITS11670mmHg while sheath removal70mmHg while sheath removalMAP for 15 minMAP for 15 minGradually reduce to 30mmHg over 2 hrs and remove.Gradually reduce to 30mmHg over 2 hrs and remove.

CLAMP-EASE

VASCULAR ACCESS,COMPLICATIONS,MERITS117

METAL PAD

C-ARM

PRESSURE PAD

• Advantages

• More effective compression

• Dis-advantages

• Doesn’t decrease time to hemostasis / ambulation.

• Patient discomfort

VASCULAR ACCESS,COMPLICATIONS,MERITS118

TOPICAL HEMOSTATIC AIDS

• A variety of topical patches, pads, bandages, and powders are available for use to assist with hemostasis with manual compression.

• Accelerate the clotting process and thus accelerate hemostasis

• Advantages

• Topical agents leave no foreign body behind, and act by

• Accelerating natural hemostasis.

• Topical agents still require manual compression

VASCULAR ACCESS,COMPLICATIONS,MERITS119

VASCULAR ACCESS,COMPLICATIONS,MERITS120

VASCULAR CLOSURE DEVICES• Introduced in 1995 to decrease vascular

complications and reduce the time to hemostasis and ambulation.

• CLASSIFICATION

• PASSIVE

• enhance hemostasis with prothrombotic material or mechanical compression, but do not achieve prompt hemostasis or shorten the time to ambulation

• ACTIVE

VASCULAR ACCESS,COMPLICATIONS,MERITS121

VASCULAR ACCESS,COMPLICATIONS,MERITS122

ANGIO-SEAL

• Success rate – • 90 - 97%*

• Advantages • One of the easiest devices to learn and use. •

• Has a very high initial success rate. •

• The collagen plug in the tract also acts to reduce oozing from the site.

• The retained components of the device are completely resorbed

• *Applegate RJ, Grabarczyk MA, Little WC et al. Vascular closure devices during percutaneous revascularization. J Am Coll Cardiol 2002;40:78–83.

VASCULAR ACCESS,COMPLICATIONS,MERITS124

• Disadvantages

• The intravascular anchor has the potential to further obstruct a heavily diseased vessel.

• Embolization of the intravascular anchor.

• Repeat access of the same vessel within 90 days of device deployment should be avoided using the same puncture site.

• Infection.

VASCULAR ACCESS,COMPLICATIONS,MERITS125

STAR CLOSE DEVICE

• Success rate

• 87%–97%*

• Advantages

• deploys on the outside of the artery, leaving nothing in the lumen.

• Re-puncture through a deployed Starclose clip performed safely at any time.

• Disadvantages

• Oozing.• *Applegate RJ, Grabarczyk MA, Little WC et al. Vascular closure devices during percutaneous

revascularization. J Am Coll Cardiol 2002;40:78–83.

VASCULAR ACCESS,COMPLICATIONS,MERITS128

• Devices:2011 ACCF/AHA/SCAI Guideline for Percutaneous Coronary Intervention Recommendations

• Class I

• 1. Patients considered for vascular closure devices should undergo a femoral angiogram to ensure their anatomic suitability for deployment.

• Class IIa

• 1. The use of vascular closure devices is reasonable for the purposes of achieving faster hemostasis and earlier ambulation

• Class III: NO BENEFIT

• 1. The routine use of vascular closure devices is not recommended for the purpose of decreasing vascular complications

VASCULAR ACCESS,COMPLICATIONS,MERITS134

TR band

VASCULAR ACCESS,COMPLICATIONS,MERITS136

FEMORAL VENOUS ACCESS

ANATOMY

VASCULAR ACCESS,COMPLICATIONS,MERITS137

• INDICATIONS

• Right heart study TPI

• IVC filter Venous access

• Puncture site

• Medial to femoral artery

• Needle held at 45 degree angle

• Skin insertion 2 cm below inguinal ligament

• Aim toward umbilicusVASCULAR ACCESS,COMPLICATIONS,MERITS138

COMPLICATIONS

Local Hematoma

Retroperitoneal hematoma

Pseudoaneurysm

AV fistula

Femoral neuropathy

Infection

DVT

VASCULAR ACCESS,COMPLICATIONS,MERITS139

SUBCLAVIAN VENOUS ACCESS

• INDICATIONS

• PPI leads

• TPI

• IVC filter

• Central venous access

• Chemoport

VASCULAR ACCESS,COMPLICATIONS,MERITS140

• Positioning• Right side preferred

• Supine position, head neutral, arm abducted

• Trendelenburg (10-15 degrees)

• Shoulders neutral with mild retraction

• Puncture site• Junction of middle and medial thirds of clavicle

• At the small tubercle in the medial deltopectoral groove

• Needle should be parallel to skin

• Aim towards the supraclavicular notch and just under the clavicleVASCULAR ACCESS,COMPLICATIONS,MERITS141

• COMPLICATIONS

• Infection Bleeding Pneumothorax

• Thrombosis Air embolization Brachial plexus injury

• AVOIDED IN

• Coagulopathy Thrombloysis Chest wall deformity

VASCULAR ACCESS,COMPLICATIONS,MERITS143

IJV ACCESS

• INDICATIONS

• TPI

• Central venous line

• Positioning• Right side preferred

• Trendelenburg position

• Head turned slightly away from side of venipunctureVASCULAR ACCESS,COMPLICATIONS,MERITS144

Needle placement

• Central approach• Locate the triangle formed by the clavicle and

the sternal and clavicular heads of the SCM muscle

• Place 3 fingers of left hand on carotid artery

• Place needle at 30 to 40 degrees to the skin, lateral to the carotid artery

• Aim toward the ipsilateral nipple under the medial border of the lateral head of the SCM muscle

• Vein is 1-1.5 cm deep, avoid deep probing in the neck

VASCULAR ACCESS,COMPLICATIONS,MERITS145

COMPLICATIONS

• Infection Bleeding – airway compression

• Thrombosis Air embolization Pneumothorax

• AVOIDED IN

• Trendelenburg tilt is not possible – pulmonary edema

• Child < 1 yr who cannot be sedated / paralysed

VASCULAR ACCESS,COMPLICATIONS,MERITS147

COMPLICATIONS

VASCULAR ACCESS,COMPLICATIONS,MERITS149

Location Advantage DisadvantageInternal Jugular

• Bleeding can be Bleeding can be recognizedrecognized

and controlledand controlled

• Malposition is rareMalposition is rare

• Less risk of Less risk of pneumothoraxpneumothorax

• Risk of carotid artery Risk of carotid artery puncturepuncture

• Pneumothorax possiblePneumothorax possible

Femoral • Easy to find veinEasy to find vein

• No risk of No risk of pneumothoraxpneumothorax

• Preferred site for Preferred site for

emergencies and CPRemergencies and CPR

• Fewer bad Fewer bad complicationscomplications

• Highest risk of infectionHighest risk of infection

• Risk of DVTRisk of DVT

• Not good for ambulatory Not good for ambulatory

patientspatients

Subclavian • Most comfortable forMost comfortable for

conscious patientsconscious patients

• Highest risk of Highest risk of pneumothrax, pneumothrax,

• Vein is non-compressibleVein is non-compressible

Thank You.

VASCULAR ACCESS,COMPLICATIONS,MERITS150

top related