valentina benitez bedoya, retrovirus
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Introduction:
Retroviruses are the exception for
the rules of the Central Genome,
because it goes from RNA to DNA
HIV, Human immunodeficiency virus
is the principal retrovirus that can
cause an stage of
immunosuppression in its guests
Discovery of HIV
Feature Provides
New Drug Target
MRC Laboratory of Molecular Biology
2016, August 15
Discovery of HIV Feature
Provides New Drug Target
The virus is not
recognized by the guest’s
immune system because
of the capsid which
doesn’t go away as the
previous thoughts.
Discovery of HIV Feature
Provides New Drug Target
The capsid has capsid pores that regulate the enter of nucleotides to the virus in order to produce de DNA.
Discovery of HIV Feature
Provides New Drug Target
The capsid pores are the new
treatment target, and they were
successfully blocked using
hexacarboxybenzene
The scientist are developing a
component that can go through the
cells membranes and attack the
capsid pores.
Discovery of HIV Feature
Provides New Drug Target
This is a very important discovery,
because each day there are a lot
people getting infected by this virus. If
there is a more efficiently treatment,
there would be better prognostic to
those patients.
HIV-Related
Retroviruses Date
Back 60 Million
Years Ago
Czech Academy of Sciences.
2016, August 11th
HIV-Related Retroviruses Date
Back 60 Million Years Ago
Retroviruses are a
type of lentiviruses
and the oldest one
was target back to 12
million years ago
HIV-Related Retroviruses Date
Back 60 Million Years Ago
The new researched
showed that the
oldest Lentivirus is
back to 60 million
years ago
HIV-Related Retroviruses Date
Back 60 Million Years Ago
They took a genomic
data from the
Malayan flying lemur,
which contains DNA
Lentiviral remnants.
They are going to
study how that
ancient virus has
evolved in order
to understanding
it more.
HIV-Related Retroviruses Date
Back 60 Million Years Ago
By knowing the date were the oldest
lentivirus infected a guest, they can
research about its evolution in order
to know this virus better, and to find
important characteristics which can
lead us to new treatment targets.
Medical Utility
Both researches are about HIV, even if they are about a different topic of HIV, they both lead the way to improve the treatments and the way we understand the disease
Medical Utility
Knowing an understanding
how the virus works, and how
the immune system cannot
detect it, is a very important
advance in order to start
thinking in new treatments
Medical Utility
Researching from when and
where the HIV virus comes, is a
very important part of getting to
know this virus because wit that,
we can see how its evolution
process has come and how we
can use it to have new
treatments for HIV disease
Bibliography Czech Academy of Sciences. HIV-Related Retroviruses
Date Back 60 Million Years Ago. Retrieved August 22, 2016 from http://www.natureworldnews.com/articles/26705/20160811/hiv-retroviruses-60-million-years-ago.htm
MRC Laboratory of Molecular Biology. Contagion. Discovery of HIV Feature Provides New Drug Target. Retrieved August 22, 2016 from http://www.contagionlive.com/news/discovery-of-hiv-feature-provides-new-drug-target-
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