the effect of herbal product interaction project

PHYTO PROJECT

1-Asmaa Khaled Shehab 51140532-Alaa Gamal lallo 51140643-Alaa Hasan Hasan 51140654-Alaa mohamed Moussa 51140715-Afnan Maher Ali 51140596-Radwa Mohamed Abdelalim 51141577-Eslam Saad sobhy 51140468-Eslam Shalaby Khamis 5114047

PRESENTED BY

Introduction About The Effect Of Herbal Product Interaction.

Aim Of Investigation.Statistical analysis for resultsdetails and information about 6 herbal combination

and 10 pharmaceutical products

Headlines:

Because dietary supplements are becoming increasingly popular, physicians need to ask questions about the use of herbal products as part of the medication history. Even though herbal products are available without a prescription, medical guidance is necessary because of the adverse effects of these products and the potential for interactions.

Consequently, physicians need to stay abreast of trends in dietary supplement use, with the realization that for most supplements the adverse effects and potential for interactions are not well characterized.

Introduction About The Effect Of Herbal Product Interaction

Gathering information about Herbs interaction from different sites “Herbal supplier, Pharmacies, And audience

Identifying some useful herbs combination and harmful herbal combination”

Knowing uses & Main constituents of this pharmaceutical products and combination

Understanding the interaction within pharmaceutical product

Indication adverse effects interaction and side effects of this products

Knowing the patient compliance to herbal products (combination ,herbal tea bags).

Aim Of Investigation

Brand Name: linden Combination– نCوCرCفCزCيCزCلCا CةCفCصCو Constituents: Guava leaves ,Tilia ,Anise , inden.Uses: treatment of wet cough and common cold.Side effects: there is no complainsComment: Interaction of this combination could cause

weakness in heart and allergy in skin. And it shouldn’t be use in pregnancy and breast feeding. (They are antagonism)

Effect Of Some Herbal Combination From Herbal Suppliers (Questionnaire 1-a)

Brand Name: halva combination اCفCلCحCلCا CةCفCصCو -Constituents: Ammi seeds, Parsley, BarleyUses: for kidney stones, salts and sedimentation of

kidney, and cure for colic.Side effects: dehydration – diuretics.Comment: should used in caution with kidney failure

patient as it may cause drought diuretics and dehydrationas the herbal supplier said used for stomachache.

Brand Name: fat burning Combination– CةCقCرCاCحCلCا CبCاCشCعCالCا لCلCدCهCوCن

Constituents: Marble , black cumin ,Mint, with other ingredient.

Uses: for weight loss Side effects: No side effectComment: this combination could cause lowering in

blood pressure ,dizziness and a having a dangerous effect to pregnant women.

Brand Name: Tilia And thymeConstituents: Tilia And thymeUses: headache & runny noseSide effects: No side effects has been recordedComment: there were no interaction, this combination

is a synergism

Herbal Tea Bags Combination (Questionnaire 1-b)

Brand Name: Royal tea/ isis ginger and cinnamonConstituents: ginger and cinnamon Uses: for weight lossSide effects: diarrheaComment: there were no interaction ,the combination

is a synergism

Brand Name: ginger and cinnamonConstituents: ginger and cinnamonUses: weight loss- enhance immunity- Side effects: may lead to increase gastric acidity Comment: after searching we found that this

interaction may lead to ulcer in stomach and gastritis, cinnamon my hurts the spleen and ginger may increase the heart beats above normal, and decrease sugar level in blood. Ginger and cinnamon may affect nervous system (they are synergism).

Trade Name: (Guava Syrup)Main Constituents: Aqueous extract of guava leaves,

Tilia Extract, fennel oil & Extract of liquorice root.Uses: Antitussive Side effects: large dose could cause diarrhea Comment:

This product shouldn’t used by uncontrolled diabetes mellitus patient

Shouldn’t be taken with ginger as Guava increase Blood glucose level while ginger decrease blood glucose level

Shouldn’t be taken with warfarin. Not to be used by pregnant women suffering from liver or

renal disease.

Herbal Products In Pharmacy(Questionnaire 3)

Trade Name: Immunavita oral drops Main Constituents:Extract of Echinacea purpurea

volatile oil, caffeine , ferulic acid derivativesUses: dietary supplement improve function of immune

systemSide effects: No Recorded side effects Comment: it may interact with immunosuppressive therapy as

Athathioprine and Cyclosprine

Trade Name: MentholaxMain Constituents: Pepperment oil & purified Senna

ExtractUses: Laxative, carminative, antispasmodicsSide effects: No Recorded side effects Comment: Senna increase toxicity of digitalis

STATISTICAL ANALYSIS

Questionnaire-2 (Audience)

Sample No: 10We collected surveys from Alexandria , Damanhur,

somoha & DossqThe females were more than males.People mainly age was 31-50.the majority of people trust in medical herbs in

treatment of some diseaseThe majority have you used medical herbs in

treatment of some disease before.People mainly brought the medical herbs form Spice

dealersAudience mainly prefer to use one herb alone rather

than group

All the people has improvement happened after using medical herbs.

In the majority no side effects has appeared.Mainly people doesn’t stop using the herbs after the

side effect appearingUsually these signs hasn’t improved after stop using

medical herbs

Comment:We collected surveys from Alexandria , Damanhur, somoha & Dossq

AREA

Area Alexandria Damanhour Somoha Dossq

  50% 40% 10% 10%

Area

AlexandriaDamanhourSomohaDossq

CommentThe females were more than males.

GENDER

Gender Male female

  20 80

Male female0

10

20

30

40

50

60

70

80

90

Gender

CommentPeople mainly age was 31-50.

AGE

Age 15-30 31-50 51-75

  30 40 30

15-30 31-50 51-750

5

10

15

20

25

30

35

40

45

Age

Comment:the majority of people trust in medical herbs in treatment of some disease.

DO YOU TRUST IN USING MEDICAL HERBS IN TREATMENT OF SOME DISEASE?

Do you trust in using medical herbs in

treatment of some disease?

Yes No

80 20

Yes No0

10

20

30

40

50

60

70

80

90

Do you trust in using medical herbs in treatment of some disease?

CommentThe majority have you used medical herbs in treatment of some disease before.

HAVE YOU USED MEDICAL HERBS IN TREATMENT OF SOME DISEASE BEFORE?

Have you used medical herbs in treatment of some disease before?

Yes No

90 10

Yes No0

10

20

30

40

50

60

70

80

90

100

Have you used medical herbs in treatment of some disease before?

CommentPeople mainly brought the medical herbs form Spice dealers

WHAT IS YOUR SOURCE TO GET MEDICAL HERBS?

What is your source to get

medical herbs?

Pharmacies spice dealer Company

40 60 0 

Pharamcies spice dealer Company 0

10

20

30

40

50

60

70

What is your source to get medical herbs?

CommentAudience mainly prefer to use one herb alone rather than group.

DO YOU PREFER TO USE ONE HERB ALONE OR AS GROUP?

Do you prefer to use one herb alone

or as group?alone group

  60 40

alone group0

10

20

30

40

50

60

70

Do you prefer to use one herb alone or as group?

CommentAll the people has improvement happened after using medical herbs.

IS THERE IMPROVEMENT HAPPENED IN MEDICAL SITUATION AFTER USING MEDICAL HERBS?

Is there improvement happened in medical situation after using

medical herbs?yes no

  100 0

yes no0

20

40

60

80

100

120

Is there improvement happened in medical situ-ation after using medical herbs?

CommentIn the majority no side effects has appeared.

IS THERE ANY SIDE EFFECTS APPEAR AFTER USING MEDICAL HERBS?

Is there any side effects appear after using medical herbs? yes no

  40 60

yes no0

10

20

30

40

50

60

70

Is there any side effects appear after using medical herbs?

CommentMainly people doesn’t stop using the herbs after the side effect appearing

HAVE YOU STOPPED USING THE HERB AFTER THE SIDE EFFECT APPEARING ?

Have you stopped using the herb after the side effect

appearing ?yes no

  40 60

yes no0

10

20

30

40

50

60

70

Have you stopped using the herb after the side ef -fect appearing ?

CommentUsually these signs hasn’t improved after stop using medical herbs

DID THESE SIGNS IMPROVED AFTER STOP USING MEDICINAL HERBS?

Did these signs improved after stop using medicinal herbs? yes no

  40 60

yes no0

10

20

30

40

50

60

70

Did these signs improved after stop using medicinal herbs?

1-Nactional Center for complementary and alterative medicine (NCCIH).

2-Ghayur,M.N, Pharmacol. 2005http://

herbs.lovetoknow.com/Side_Effects_of_Herbal_Medicine

Reference

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