the advantage ® valve valve design and clinical results “our experience, your advantage”

The ADVANTAGEThe ADVANTAGE®® Valve Valve

Valve Design and Clinical ResultsValve Design and Clinical Results

“Our Experience, Your Advantage”

The ADVANTAGE® Valve

• Pyrolytic carbon constructionPyrolytic carbon construction• Cylindrical housingCylindrical housing• Double velour polyester sewing ringDouble velour polyester sewing ring• Rotatable designRotatable design• Leaflet opening angle: 86Leaflet opening angle: 86°, closing angle: 22° °, closing angle: 22° • Patented Sure FlowPatented Sure Flow™™ pivot recess design pivot recess design

Evolutionary approach for facilitated implantation and quality of flow

The ADVANTAGE® Valve

Low profile housingLow profile housing

• Optimizes implantability with minimal ventricular Optimizes implantability with minimal ventricular

intrusionintrusion

• Generous sewing cuff for easier suturing and Generous sewing cuff for easier suturing and

compliancecompliance

ADVANTAGE® Valve St. Jude Medical® Valve

The ADVANTAGE® Valve

Widened outflow channel designed for Widened outflow channel designed for improved washingimproved washing

Patented Patented SureFlowSureFlow™ ™ Pivot RPivot Recessecess

Computational Fluid Dynamics*

*Unsteady 3-D computational Fluid Dynamic Simulation of Medtronic Model 7760 Prosthetic Mechanical Heart Valve (Aortic) Adaptive Research, Alhambra, CA, 2001.

Widened outflow channel increases pivot washing, Widened outflow channel increases pivot washing, reduces potential for thrombosisreduces potential for thrombosis

ADVANTAGEADVANTAGE® ® Valve Valve St. Jude MedicalSt. Jude Medical®® Valve Valve

Computational Fluid Dynamics*

*In vitro analysis conducted by the School of Mechanical Engineering, Cardiovascular Fluid Mechanics Laboratory, Georgia Institute of Technology

ATS Medical™

Valve

18-19%

ADVANTAGE® Valve

20-22%

CarboMedics Valve

18-19%

St. Jude Medical® Valve

18-19%

Enlarged Central Flow Area

Enlarged central flow area is designed to reduce turbulenceEnlarged central flow area is designed to reduce turbulence

Computational Fluid Dynamics*

*Unsteady 3-D computational Fluid Dynamic Simulation of Medtronic Model 7760 Prosthetic Mechanical Heart Valve (Aortic) Adaptive Research, Alhambra, CA, 2001.

St. Jude MedicalSt. Jude Medical®® Valve ValveADVANTAGEADVANTAGE® ® ValveValve

Vmax = 1.80 Vmax = 2.45

Computational Fluid Dynamics*

St. Jude MedicalSt. Jude Medical®® Valve ValveADVANTAGEADVANTAGE® ® ValveValve

*Unsteady 3-D computational Fluid Dynamic Simulation of Medtronic Model 7760 Prosthetic Mechanical Heart Valve (Aortic) Adaptive Research, Alhambra, CA, 2001.