systemic approach to advanced colon cancer mohamed abdulla (m.d.) ass. prof. clinical oncology kasr...

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Systemic Approach to Advanced Colon

CancerMohamed Abdulla (M.D.)

Ass. Prof. Clinical OncologyKasr El-Aini School of Medicine

Cairo UniversityApril, 2005

Heterogeneous Groups of Patients Several Agents

Different SchedulesPharmacogenomic

Variations

Which Regimen to Be Used as a First Line ttt in Advanced or Metastatic Colon

Cancer???

DON’T FORGET

5-Fu is no longer the only cytotoxic agent with clinical activity.

Capecitabine is an effective alternative to infusional 5-Fu.

Oxaliplatin & Irinotecan have nearly doubled the median survival.

Oxaliplatin improves PFS. Initial validation of the promising

systemic target therapies.

Highlights of the American Society of Clinical Oncology 2005 Gastrointestinal Cancers Symposium, Feb. 2005.

Seminars in Oncology; Volume 32, Number 1, 2004-2005.

www.medscape.com www.mdconsult.com

ANNOUNCEMENT

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