synthesis and biological evaluation of 9-thia-5,10-dideazafolic acid
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2002 Vitamins
VitaminsU 0900 Synthesis and Biological Evaluation of 9-Thia-5,10-dideazafolic Acid. — The title
compound (VII) is a potent inhibitor of human 5-aminoimidazole-4-carboxamide ribo-nucleotide transformylase and is active against a leukaemia RPMI-8226 cell line. — (WALL, M.; BENKOVIC*, S. J.; J. Heterocycl. Chem. 39 (2002) 5, 1097-1099; Dep. Chem., Pa. State Univ., University Park, PA 16802, USA; Eng.) — D. Singer
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