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Name: Denis Warwick King Address: c/o Sydney Colorectal Associates Ground Floor, Hurstville Private Hospital 37 Gloucester Road Hurstville NSW 2220 Awards: Medal of the Order of Australia in the General Division (2010) Degrees: MB BS Sydney University 1966 FRACS 1970 Current Appointments: Visiting Medical Officer Colorectal Unit St George Hospital Clinical Professor Graduate School of Medicine University of Wollongong
Clinical Associate Professor UNSW Chair Illawarra and Shoalhaven Local Health District Board Chair NSW Health Ministerial Advisory Committee Member Council University of Wollongong
3
Previous Appointments:
1966 Intern, St. George Hospital
1967 Senior Resident Medical Officer
St. George Hospital
1968 Demonstrator
School of Anatomy
University of Sydney
1969-1970 Surgical Registrar
St. George Hospital
1971 Senior Surgical Registrar
St. George Hospital
1972 Lecturer in Surgery
University of Singapore
Singapore General Hospital
1973 Surgical Registrar
Royal Salop Infirmary
Shrewsbury, Shropshire
1974 Commonwealth Registrar
St. George's Hospital, London
Clinical Assistant
St. Mark's Hospital, London
1975 Research Fellow
St. Mark's Hospital, London
1976 Clinical Superintendent
St. George Hospital, Kogarah
1990-1995 Director
Division of Surgery
St George Hospital
2000-2003 Director
Division of Critical Care and Surgery
St George Hospital
2003-2005 Chair, Surgical Stream
South East and Illawarra Health Service
4
2000-2008 Strategic Advisory Board
John Curtin School of Medical Research (2000- 08)
2006-2009 Executice Clinical Director
South Eastern Sydney & Illawarra Area Health Service
2007-2010 Chairman, Board, Continuum Health Care
2007-2010 Board of Directors
St George Medical Research Foundation
Membership of Societies:
St. Mark's Association
Surgical Research Society of Australia
Sydney Colorectal Surgical Society (Foundation Member)
Colorectal Surgical Society of Australia (Foundation Member)
Journal Associations:
Member, Consultant Board, International Journal of Colorectal Disease
Reviewer Medical Journal of Australia
Reviewer Diseases of the Colon & Rectum
5
Committee Membership:
1986-88 President, Sydney Youth Orchestra Association
1988-89 Chairman, Medical Staff Council, St. George Hospital
Chairman, St. George Hospital Planning Committee
1990 - New South Wales Department of Health Oncology Advisory
Committee
1991-92 Chairman, Cancer Centre Working Party, St. George Hospital
1992 Reid-Harris Committee
1994 - Waiting List and Emergency Department Working Party,
NSW Health
1995 - 96 Clinical Standards Group, Clinical Costing Project
1995 - 96 Member, Reference Group
Member, Implementation Committee
Member, Best Practice Group
Waiting List Implementation Project, NSW Health
2004 – 2006 Member
Surgical Services Task Force
NSW Health
6
Health Management:
Director Special Projects (Clinical Services)(1994-96)
Southern Sydney Area Health Service
Director MA International - reviews conducted
• Clinical Management Structure Auckland General Hospital (1995)
• Feasibility study Indonesian National Referral Hospital (for
AusHealth)(1996)
• Surgical Services Alfred Hospital, Melbourne (1997)
• Clinical Services Whyalla Hospital (for South Australian Dept Health)
(1997)
• Surgical Services Geelong Hospital (1998)
• Clinical Services Albury Base Hospital (for Greater Murray Area
Health Service) (1998-99)
• Clinical Services Mid-Western Area Health Service (1999)
• Surgical Services Richmond Valley (for Northern Rivers Area Health
Service (1999)
• Broken Hill Hospital Clinical Services (for Far Western Area Health
Service) (2000)
• ACT Surgical Services (for ACT Health) (2000)
• Review Clinical Services Peel AHS (WA) (2001)
• Review Operating Theatres Nepean Hospital (2001)
• Review Clinical Services Nepean Hospital (with M Gleeson) (2002)
• Review Clinical Services Lithgow Private Hospital (2002)
• Review Surgical Services Royal North Shore and Ryde Hospitals
(2004)
• Development of Clinical Services Plan Northern Sydney and Central
Coast AHS (2008)
• Review of Clinical Engagement in NSW Health Services – NSW Health
(with A McCarroll) (2008)
• Review Perioperative Service Prince Charles Hospital, Brisbane(2008)
• Review Pain Management and Research Service – Royal North Shore
Hospital (2009)
7
Presentations at Scientific Meetings/Abstracts:
1. Surgical Research Society of Australasia
Dunedin NZ, 19th September 1987
King D W, Lubowski D Z, Bruck C E. Do patients with haemorrhoids have pelvic floor
denervation?
(Selected by SRSA for presentation at SRS UK meeting, Bristol, July 1987)
2. Sydney Colorectal Surgical Society Scientific Meeting
Orange, 19th March 1988
Lubowski D Z, King D W. What is the best way of measuring external anal sphincter function?
3. Sydney Colorectal Surgical Society Scientific Meeting
Orange, 19th March 1988
King D W, Lubowski D Z. The relation between utero-vaginal prolapse and pelvic floor
denervation.
4 & 5. Royal Australian College of Surgeons, General Scientific Meeting
Brisbane, 4th May 1988
Lubowski D Z, King D W. Do patients with haemorrhoids have pelvic floor denervation?
Sigmoid strictures at colonoscopy - an indication for surgery.
King D W, Armstrong A, Lubowski D.
6. Royal Australasian College of Surgeons, General Scientific Meeting
Brisbane 4th May 1988
Sigmoid strictures at colonoscopy - an indication for surgery.
7 & 8. American Society of Colon and Rectal Surgeons Meeting
California, 14th June 1988
Lubowski D Z, King D W, Finlay I G. Failure of contraction of pubococcygeus muscle as a cause of
obstructed defaecation.
King D W, Lubowski D L, Bruck C E. Do Patients With Haemorrhoids Have Pelvic Floor
Denervation? (Poster presentation)
9. Surgical Research Society, Tripartite Meeting (UK SRS, European SRS, Society of University
Surgeons),
Bristol, UK, 7th July 1988
Lubowski D Z, King D W, Bruck C E. Do patients with haemorrhoids have pelvic floor
denervation?
10 Royal Australasian College of Surgeons, NSW State Committee ASM
Sydney, 17th September 1988
Beevors M, King D W. Appendicectomy audit.
8
11. Sydney Colorectal Surgical Society Annual Scientific Meeting
Sydney 12th November 1988
Staging - why bother?
12. Sydney Colorectal Surgical Society Scientific Meeting
Sydney, 4th February 1989
Colonoscopy - Changing indications.
13. Royal Australasian College of Surgeons Annual Scientific Meeting
Melbourne, 10th May 1989
Lubowski D Z, King D W. The pelvic floor in obstructed defaecation
14,15,16. American Society of Colon and Rectal Surgeons Annual Scientific Meeting
Toronto, Canada June 1989
King D W, Lubowski D Z. The relationship between utero-vaginal prolapse and pelvic floor
denervation
Lubowski D Z, King D W, Cook T. Should the anal mucosa be removed in restorative
proctocolectomy for ulcerative colitis (poster presentation)
Lubowski D Z, King D W. Colon transit in health and constipation assessed using oral I-131
(poster presentation)
17,18.19. Tripartite Meeting (RSM, ASCRS, RACS)
Birmingham, UK, 20th June 1989
Lubowski D Z, King D W, Cook T A. Should the anal mucosa be removed in restorative
proctocolectomy for ulcerative colitis?
King D W, Lubowski D Z, McLean R, Bruck C E, Tallet N A. Colonic transit time determined by
radionucleotide imaging in patients with constipation.
King D W, Lubowski D Z, Beevors M A, Carlton M A. Pelvic floor function in uterovaginal
prolapse (poster presentation)
20. Royal Australasian College of Surgeons Annual Scientific Meeting
Sydney, 18th August 1990
Lubowski D Z, King D W, McLean R, Smart R, Gaston-Parry D. Colon transit in health and
constipation - analysis of oral In-111 DTPA
Awarded State Committee Medal for Best Fellows Paper at ASM
21,22,23,24. Royal Australasian College of Surgeons General Scientific Meeting
Sydney, 9th May 1991
Lam T, Lubowski D Z, King D W. Posterior pelvic floor repair for obstructed defaecation.
9
Kooner R, King D W, Lubowski D Z. Faecal incontinence - Selection of patients and results of
treatment.
Lam T, Lubowski D L, King D W. Does squatting reduce pelvic floor descent and pelvic nerve
damage?
Morris D L, Dilley A V, Warlters A, Horton M, Clingan P, Tindal D, King D W. Hepatic Cryotherapy
for Metastases - Greater Effect of Twin Freeze/Thaw Cycle
25. St. Mark's Association Meeting
London, 28th June 1991
Lubowski D Z,King D W, McLean R G, Smart R. Oral In-111 DTPA Scintigraphy: its value for
routine clinical assessment of colon transit
26. Academy of Medicine, Silver Jubilee Meeting
Singapore, 9th November 1991
Lubowski D Z, King D W, McLean R G, Smart R, Gaston-Parry D. Oral In-111 DTPA Scintigraphy:
its value for routine clinical assessment of colon transit in severe constipation
27. American Society of Colon and Rectal Surgeons
5th May1993
Meagher AP, Adams WJ, Lubowski DZ, King DW
Autonomic nerves cross the plane of posterior rectal dissection
(poster presentation)
28. Sydney Colorectal Surgical Society Scientific Meeting
Sydney, 17th July 1993
Topical glyceryl trinitrate in the management of anal fissures.
29,30,31,32,33. Tripartite Colorectal Meeting
Sydney, 17-20th October 1993
King D, Adams W, Meagher A, Lubowski D.
Pretreatment with bisacodyl reduces the volume of polyethylene glycol solution required for
bowel preparation.
Lubowski D, Meagher A, Sun W, King D.
A prospective trial of biofeedback vs placebo for the treatment of anismus
Lubowski D, Meagher A, King D, Smart R, Butler P.
A scintigraphic study of colonic function during defaecation.(poster presentation)
Adams W, Meagher A, Lubowski D, King D.
Autonomic nerves cross the plane of posterior rectal dissection.(poster presentation)
Lubowski D, Meagher A, King D.
Physiological measurement of external sphincter pressure: To squeeze or cough?
10
Lubowski D, Meagher A, King D. (poster presentation)
34.British Society of Gastroenterology Scientific Meeting
Manchester 23rd-24th March 1994
Adams W, King D, Lubowski, Morris DL.
Cimetidine prevents postoperative Suppression of Immune Function Following Colorectal
Cancer Surgery
35,36,37 Royal Australasian College of Surgeons Annual Scientific Meeting
Hobart 1st-6th May 1994
Young C, King D, Lubowski D, Jorgensen J
Oral Sodium Phosphate Solution is a Superior Preparation to Polyethylene Glycol with Bisacodyl
Kennedy M, Lubowski D, King D
Glyceryl Trinitrate for Anal Fissure
Young C, Kennedy M, Lubowski D, King D
Post-anal Repair for faecal incontinence
38,39,40 Surgical Research Society of Australasia Annual Meeting
St Vincent’s Clinic Sydney August 1994
Kennedy ML, Lubowski DZ, King DW
Chemical Sphincterotomy for Anal Fissure - a new treatment
King J, Dasappa VK, Ross WB, King DW, Clingan P, Morris DL
Survival of Patients with Synchronous Colectomy & Intrahepatic Chemotherapy
Stewart GJ, Preketes AP, Lubowski DZ, King DW, Morris DL
Colorectal Cancer Response to High Dose Sandostatin Therapy: A Clinical Trial
41 Sydney Colorectal Surgical Society
Thredbo, 12-14 August 1994
Chen FC, Kennedy ML, Lubowski DZ, King DW.
Subtotal Colectomy for Slow transit Constipation
42 Sixth National Casemix Conference, Commonwealth Dept of Human Services and Health
Hobart 31 August 1994
King DW, Kidd J, Stahel R
Clinical Budgeting - The St George Experience
43 Australian Gastroenterology Week (Gastroenterological Society Meeting)
Sydney September 1994
Young C, Kennedy ML, Lubowski DZ, King DW
Post-anal repair for Faecal Incontinence - long term results (poster)
11
44 ASM NSW State Committee, Royal Australasian College of Surgeons
Pokolbin 10/11 Sep 1994
Young C J, Jorgensen J O, King D W, Lubowski D Z
Oral Sodium Phosphate Solution is a superior Colonoscopy Preparation to Ployethylene Glycol
with Bisacodyl
45 American Society of Colon and Rectal Surgeons, Washington, June 1996
Talley N A, Chen F, King D, Jones M, Talley N J
Short-Chain Fatty Acids in the Treatment of Radiation Proctitis
46. 3rd
Australian peptide Conference – From Discovery to Therapeutics – Oct 1998
Burcher E, Warner FJ, Shang F, Markus I, Lubowski DZ, King DW
Characterisation and autoradiographic localization of tachkynin receptors in human colon
47. Western Pharmacol. Soc., Maui, USA, Feb 1999
Burcher E, Warner FJ, Shang F, Markus I, Liu L, Lubowski DZ, King DW
Tachykinins in human colon
48 American Gastroenterological Association Conference, Atlanta. May 2001
Dinning PG, Bampton PA, Andre J, Kennedy ML, Lubowski DZ, King D, Cook IJ
Constipation due to obstructed defaecation is likely to be a colonic rather than an anorectal
disorder
49 Sydney Colorectal Surgical Society
St George Private Hospital 28Jul01
Preoperative CT: selection of patients for combined colon and liver resection or hepatic artery
chemotherapy
50. GI Motility Symposium; Murdoch Children’s Research Institute; Royal Children’s Hospital,
Melbourne. 20Apr02
Azriel Y, Grimm M. Lubowski D, King D, Burcher E
Neurotensin in idiopathic slow transit constipation
51. GI Motility Symposium; Murdoch Children’s Research Institute; Royal Children’s Hospital,
Melbourne. 20Apr02
Burcher E, Shang F, liu L, Markus I, King D, Lubowski D
Mechanism of tachykinin induced contraction in the human colon
52. American Gastroenterological Association Conference, San Francisco. May 2002
Dinning PG, Bampton PA, Kennedy ML, Lubowski DZ, King D, Cook IJ
Heightened rectal sensory thresholds and blunted recto-colonic motor reflexes implicated in
constipation due to obstructed defaecation
53. AHMR, Melbourne, Dec 2002
Azriel Y, Grimm M. Lubowski D, King D, Burcher E
Alterations in neurotensin receptors and responsiveness in slow transit constipation
12
54, 55, 56. Annual Scientific Congress, Royal Australasian College of Surgeons, Brisbane May
2003
Khoo OKS, Kadir A, Balalla B, King DW, Perera DS
Abdominal distension and post colonoscopy pain.
Schmidt LM, Williams P, Khoo OKS, King DW, Perera DS
Oral sodium picosulfate is a superior colonoscopy preparation compared to sodium phosphate
Fernando SC, Haghighi KS, Chu F, King J, King DW, Lubowski DZ, Zhao J, Morris DL
Synchronous approach to liver metastases from colorectal cancer: Longterm survival and
indicators of prognosis after hepatic resection and chemotherapy
57. Australian Gynaecological Endoscopic Surgical Conference 17th
May 2003
Thornton MJ, Lam A, King DW
Laparoscopic or transanal repair of rectocoele? A retrospective matched cohort study.
58, 59. Australian Gastroenterological Society, Cairns 8th
October 2003
Thornton MJ, Kennedy ML, Lubowski DZ, King DW
Vaildation of the high frequency wave form demonstrated in the hypertonic anal sphincter: The
Fast Wave
Thornton MJ, King DW, Lubowski DZ, Cross KM, Glenn D
Assessment of the value of the pre-operative abdominal CT in colorectal cancer
60, 61, 62, 63. American Gastroenterological Society, Baltimore, USA, 13th
October 10-15, 2003
Thornton MJ, Kennedy ML, Lubowski DZ, King DW
Validation of the high frequency wave form demonstrated in the hypertonic anal sphincter: The
Fast Wave
Journal of Gastroenterology and Hepatology 2003; 18(suppl): A B44
Thornton MJ, Kennedy ML, Lubowski DZ, King DW
Long-term follow-up of the dynamic graciloplasty reconstruction for faecal incontinence.
Saafan AK, Thornton MJ, Gebski V, Burcher E, Shang F, King DW
The prevalence of diverticular disease in patients with slow transit constipation.
Journal of Gastroenterology and Hepatology 2003; 18(suppl): A B42
Cosman D, Thornton MJ, Cross KM, King DW, Morris DL
Hepatic metastases from colorectal cancer: analysis of morbidity and mortality of synchronous
treatment
64. Thornton MJ, Cross KM, King DW, Lubowski DZ, Morris DL
Assessment of the value of the preoperative abdominal CT in colorectal cancer
Journal of Gastroenterology and Hepatology 2003; 18(suppl): A B4
13
65, 66, 67. 19th
International Symposium on Gastrointestinal Motility, Barcelona, Spain October
5-8, 2003
Burcher E, Shang F, King D, Lubowski D
Actions of tachykinin and acetylcholine in human taenia coli: changes in disease
Reduction in Neurotensin receptors and neurotensin mediated contractile responses in Slow
Transit Constipation. (poster)
Azriel Y, Burcher E, Grimm M, Lubowski D, King D
The frequency of retrograde colonic propagating sequences may depend on colonic loading.
(poster)
Dinning P, Cook I, Bampton P, Lubowski D, King D, Kennedy M.
68, 69. Australian College of Surgeons ASC, Melbourne, May 2004.
Thornton MJ, Kennedy ML, King DW, Lubowski DZ.
Long-term follow-up of the dynamic graciloplasty reconstruction for faecal incontinence.
Botulinum Toxin for chronic anal fissure: prospective manometric assessment of 60 patients.
Thornton MJ, Kennedy ML, King DW.
70, 71, 72. Association of Coloproctology of Britain and Ireland, Birmingham, UK, June 2004.
Thornton MJ, Kennedy ML, King DW.
Botulinum Toxin for chronic anal fissure: prospective manometric assessment of 60 patients.
Long-term follow-up of the dynamic graciloplasty reconstruction for faecal incontinence.
(poster)
Thornton MJ, Kennedy ML, King DW, Lubowski DZ.
Validation of the high frequency wave form demonstrated in the hypertonic internal anal
sphincter: the Fast Wave. (poster)
Thornton MJ, Kennedy ML, King DW, Lubowski DZ.
73. American College of Colon and Rectal Surgery, Philadelphia, USA, April 2005.
Thornton MJ, Kennedy ML, King DW.
Botulinum Toxin for chronic anal fissure: prospective manometric assessment of 60 patients.
14
Invited Presentations:
1. Royal Prince Alfred Hospital, Surgical Guest Lecture.
Restorative Proctocolectomy
Sydney, 8th March 1988
2. Royal Australasian College of Surgeons CME Programme
Flinders Medical Centre, Adelaide, 26th March 1988
Colonoscopy - Normal landmarks; Demonstration
3. Royal Australasian College of Surgeons, Annual Scientific Meeting
Brisbane, 3rd May 1988
Pathophysiology of Obstructed Defaecation
4. Gastroenterological Society of Australia, Scientific Meeting
Newcastle, 7th October 1989
Surgical management of constipation.
5. Royal Australian College of Medical Administrators
Sydney, 1st November 1990
The Organisation of Health Services in the 1990’s
6. Royal Australasian College of Surgeons General Scientific Meeting
Sydney, May1991
Colonoscopy Workshop: Technique and Demonstration
7. Royal Australasian College of Surgeons CME Programme
Brisbane, 1991
Surgical management of rectal prolapse
8. Royal Australian College of Medical Administrators
Sydney, 28th May 1992
The Organisation of Health Services in the 1990's - A Clinical Divisional View
9,10. University of Wollongong Graduate School of Health and Medical Sciences
Sydney, June 1993
The Australian Health Care System: Policy and Politics
"Who Makes the rules"
"Professions in Transition"
11. Community Health Forum, Eastern Area Health Service
Sydney, 27th August 1993
Acute Health Homecare: Budgets and Cost Effectiveness
12.Clinical Budgeting Workshop
Policy and Planning Branch, Queensland Health
Brisbane,16Sep94
15
13.Executive Education Seminars SSAHS 25Jul94
“Strategic Directions in Health Care”
14. National Programme of Management Development for Australian Clinicians
Melbourne 24-25Nov94
“Management is not Administration”
15. “Clinical Management”
Toowoomba Hospital
Toowoomba 13Feb95
16. “The Relevance of Costing and Clinical Budgeting to Clinicians”
“Economics of Health Care”
“Information Systems and Clinical Management”
Prince Charles Hospital, Brisbane, 25May95
17. “Best Practice - NDHP Perspective
NSW Health Best Practice Seminar
Sydney 07Aug95
18. “Motivating Doctors for Cultural Change”
AHA Congress 95
Adelaide, 27Oct95
19. “The Future of Large Teaching Hospitals”
Orientation Program for NSW Health Directors
Sydney, 16Aug96
20. “The Difficult Polyp”
RACS Section of Colorectal Surgery CME Conference/Sydney Colorectal Surgical Society
Sydney, 09Nov96
21. “Quality in Australian Health Care”
World Bank study tour
Sydney, Feb97
22. “Colonoscopic screening: how often is too often?”
ASM Sydney Colorectal Surgical Society
Sydney Nov99
23. “Screening tests for bowel cancer and investigaying bowel symptoms
NSW Cancer Council and St George Division of General Practice
28th
August 2001
24. “Chronic constipation following pelvic surgery’
Pelvic Floor Symposium, Australian Gynaecological Endoscopy Society
14th
September 2001
16
25. ‘Screening tests for bowel cancer”
Prevention, Screening and Familial Aspects of Bowel Cancer
The Cancer Council, NSW
29th
August 2001
26. “Synchronous treatment of primary and secondary colorectal cancer – The St George
experience”
St George Liver Oncology Group
19th
October 2003
27. “Recent advances in Colorectal Cancer”
Gujarat Cancer and Research Institute, Ahmedabad, India
31st May 2004
28. Screening colonoscopy- indications
Royal Australasian College of Surgeons CME Programme
September 2004
17
Publications - Original Articles:
1. Brooke B N, Cave D R, King D W.
The place of Azathioprine for Crohn's Disease
Lancet 1976; 1041-42
2. King D W.
Melaena due to ectopic pancreas in enteric duplication - a case report
Singapore Medical Journal 1976, 17:56-57
3. Hanel K C, King D W, McAllister E T, Reiss-Levy E.
Single-dose Parenteral Antibiotics as Prophylaxis Against Wound Infections in Colonic
Operations
Diseases of the Colon and Rectum 1980, 23:98-101
4. King D W, Lubowski D Z, Talley N A, Pryor D S.
Restorative proctocolectomy with ileal reservoir and ileoanal anastomosis - a clinico-
physiological study.
Aust NZ J Surg 1987; 57:555-558
5. Bruck C E, Lubowski D Z, King D W.
Do patients with haemorrhoids have pelvic floor denervation?
International J Colorectal Dis 1988; 3:210-214
6. Lubowski D Z, King D W
Recto-anal reflex after rectal excision. Br J Surg 1988; 75:1150 (letter)
7. King D W, Lubowski D Z, Cook T A.
Anal canal mucosa in restorative proctocolectomy for ulcerative colitis.
Br J Surg 1989; 76: 970-972
8. McLean R G, Smart R C, Gaston-Parry D, Barbagallo S, Baker J, Lyons N R, Bruck C E, King D W,
Lubowski D Z, Talley N A.
Colon transit scintigraphy in health and constipation using oral I-131 cellulose.
J Nuclear Med 1990; 31:985-989
9. King D W, Lubowski D Z, Armstrong A S.
Sigmoid stricture at colonoscopy - an indication for surgery.
International J Colorectal Dis 1990; 5:161-163
10. Beevors M A, Lubowski D Z, King D W, Carlton M A.
Pudendal nerve function in women with symptomatic utero-vaginal prolapse.
International J Colorectal Dis 1991; 6:24-28
11. Smart R C, McLean R G, Gaston-Parry D, Barbagallo S, Bruck C E, King D W, Lubowski D Z,
Talley N A.
18
Comparison of I-131 cellulose and I-111 DTPA as tracers for colon transit scintigraphy - analysis
by colon activity profiles.
J Nuclear Med 1991; 32:1668-1674
12. Lubowski D Z, King D W
Faecal Incontinence (review article)
The National Continence Newsletter, Continence Foundation, No VAW8179 p14 1991
13. Lubowski D Z, King D W, Finlay I G.
Electromyography of the pubococcygeus muscles in patients with obstructed defaecation.
International J Colorectal Dis 1992; 7:184-187
14. McLean R, Smart R C, Lubowski D Z, King D W, Barbagallo S, Talley N A.
Oral colon transit scintigraphy using indium-111 DTPA: variability in healthy subjects.
International J Colorectal Dis 1992; 7:173-176
15. Merrett N D, Lubowski D Z, King D W.
Torsion of the vermiform appendix: a case report and review of the literature.
Aust NZ J Surg 1992; 62:981-983
16. Lubowski DZ, King DW, Lam TCF.
Surgical Management of Anal Incontinence
Annals Academy of Medicine, Singapore 1992; 21:280-283
17. Jorgensen J, Stein P, King D W, Lubowski D Z.
The anorectal angle is not a reliable parameter on defaecating proctography.
Aust NZ J Surg 1993; 63:105-108
18. Lam T C F, Islam N, Lubowski D Z. King D W.
Does squatting reduce pelvic floor descent during defaecation?
Aust NZ J Surg 1993; 63:172-174
19. Meagher AP, Lubowski DZ, King DW.
The cough response of the anal sphincter
Intnl J Colorectal Dis
1993, 8:217-219
20. Salaman JR, Griffin PJ, Ross WB, Lubowski DZ, King DW, Peters L, Nour R, Quinn RJ, Morris
DL, Butler SP
Avid thallium uptake in hepatic carcinoid metastases
Eur J Nucl Med 1993; 20(9); 804-6
21. Adams W J, Meagher A P, Lubowski D Z, King D W.
Bisacodyl reduces the volume of polyethylene glycol solution required for bowel preparation.
Dis Colon Rectum 1994;37;229-234
22. Adams WJ, Morris DL, Ross WB, Lubowski DL, King DW, Peters L
19
Cimetidine preserves non-specific immune function after colonic resection for cancer
Aust N Z J Surg 1994;34;847-852
23. Young C, Kennedy ML, Lubowski DZ, King DW
Post-anal Repair for Faecal Incontinence - long term follow-up
Journal of Gastroenterology and Hepatology 1994;9;A113
24. Lubowski DZ, King DW
Obstructed Defecation: Current Status of Pathophysiology and Management
Aust. N.Z.J. Surg. (1995) vol65, 87-92
25. McLean R, Smart R, Barbagallo S, King D, Stein P, Talley N
Colon Transit Scintigraphy Using Oral Indium-111-Labelled DTPA. Can Scan Pattern Predict Final
Diagnosis?
Digestive Diseases and Sciences, (1995) vol40, 2660-2668
26. Dasappa V, Ross WB, King J, King DW, Clingan PR, Morris DL
Primary resection and synchronous regional hepatic chemotherapy or cryotherapy for
colorectal cancer with liver metastases.
Intnl J of Colorectal Disease 1996;11;nr1;38-41
27. Brookes SJH, Lam TCF, Lubowski DZ, Costa M, King DW
Regeneration of nerves across a colonic anastomosis in the guinea-pig
Journal of Gastroenterology and Hepatology (1996) vol11, 325-334
28. Kennedy ML, Nguyen H, Lubowski DZ. King DW
Stimulated gracilis neosphincter: A new procedure for anal incontinence
Aust. N.Z.J. Surg. (1996) vol66, 353-357
29. Lubowski DZ, Chen FC, Kennedy ML, King DW
Results of colectomy for severe slow transit constipation
Dis Colon Rect 1996; 39:23-29
30. Talley NA, Chen FC, King DW, Jones M, Talley NJ
Short-Chain Fatty Acids in the Treatment of Radiation Proctitis
Dis Colon Rect 1997; 40:1046-1050
31. McLean RG, King DW, Tallet NA, Tait AD, Frieman J
The Utilization of Colon Transit Scintigraphy in the Diagnostic Algorithm for Patients with
Chronic Constipation
Digestive Dis and Sciences 1999; 44:1;41-47
32. Finlay IG, Dwerryhouse SJ, King J, King DW, Lubowski DZ, Morris DL
The effect of a short preoperative course of cimetidine on the grade of TIL in primary colorectal
cancer - a randomised controlled clinical trial
GI Cancer (1999) vol3, 121-127
33. Kelly M, King J, Cherian M, Dwerryhouse S, Finlay I, Adams W, King DW,
20
Lubowski DZ, Morris DL
Randomised trial of preoperative cimetidine in patients with colorectal cancer with quantitative
assessment of tumour - associated lymphocytes
Cancer (1999) vol 85, 1958-63
34. Horsell KW, Merten S, Clingan PR, King DW, Morris DL
Peritonectomy and intraperitoneal chemotherapy in appendiceal and colorectal cancer
Aust NZ J Surg (1999) 69:729-32
35. Young CJ, Simpson RR, King DW, Lubowski DZ
Oral sodium phosphate is a superior colonoscopy preparation to polyethylene glycol with
bisacodyl
Dis Colon Rectum 2000; 43:1568-1571
36. S Chew, King DW
Use of Endoscopic Titanium Stapler in Rectal Anastomotic Stricture
Dis Colon Rectum 2002;45;283-285
37. M L Kennedy, D Z Lubowski, D W King
Transanal Endoscopic Microsurgery. Is Anorectal Function Compromised?
Dis Colon Rectum 2002;45;601-604
38. L Schmidt, P Williams, D King, S Perera
Picoprep-3 is a superior colonoscopy preparation compared to Fleet
Dis Colon Rectum 2004;47(2);238-242
39. Dinning PG, Bampton PA, Andre J, Kennedy ML, Lubowski DZ, King DW, Cook IJ
Abnormal predefecatory colonic motor patterns define severe constipation in obstructed
defecation
Gastroenterology 2004;127(1):49-56
40. Wong SW, King DW
Surgical Techniques; Sutureless Intestinal Plication
ANZ J Surg 2004;74(8):681-83
41. Thornton MJ, Kennedy ML, King DW, Lubowski DZ
Long-term follow-up of dynamic graciloplasty for faecal incontinence
Colorectal Disease 2004;6:470-76.
42. Dinning PG, Bampton PA, Andre J, Kennedy ML, Lubowski DZ. King DW, Cook IJ.
Abnormal predefecatory colonic motor patterns define constipation in obstructed defecation.
Gastroenterology 2004; 127:49-58
43. Thornton MJ, Kennedy ML, King DW,Lubowski DZ.
The High Frequency Wave Form (Fast Qave) in the hypertonic internal anal sphincter. Validation
of a new observation.
Colorectal Disease 2004; 6(suppl 1): 69
21
44. Thornton MJ, Lam A, King DW
Laparoscopic or pelvic floor repair of rectocoele? A retrospective matched cohort study.
Dis Colon Rectum 2005;48:792-98
45. Thornton MJ, Lam A, King DW
Bowel, bladder and sexual function in women undergoing laparoscopic posterior compartment
repair in the presence of apical or anterior compartment dysfunction.
Aust NZ J Obstet Gynaecology 2005;45:195-200
46. Thornton MJ, Kennedy ML, King DW
Botulinum Toxin for chronic anal fissure: prospective manometric assessment of 60 patients.
Dis Colon Rectum 2005;48(7):1424-31
(Paper awarded Mark Killingback Prize for Colorectal Research at the ANZCS ASC Melbourne
May 2004)
47. Thornton MJ, Kennedy ML, King DW
Manometric assessment of acute anal fissure and physiological effect of topical glyceryl
trinitrate – prospective trial
Dis Colon Rectum 2005;48960: 1207-12
48. Dinning PG, Bampton PA, Kennedy ML, Lubowski DZ, King DW, Cook IJ
Impaired proximal colonic motor response to rectal and chemical stimulation in obstructed
defecation. Dis Col Rectum 2005; 48(9): 1777-1784
49. Thornton MJ, Kennedy ML, King DW, Lubowski DZ
Electromagnetic stimulation of the Pelvic Floor for idiopathic faecal incontinence: effect on
anorectal physiology
Dis Colon Rectum 2005;38(10):1945-50
50. Thornton MJ, Lubowski DZ, Kennedy ML, King DW
Faecal Incontinence, a multifactorial problem. (submitted for publication)
51. Dinning PG, Fuentealba SE, Kennedy ML, Lubowski DZ, King D, Cook IJ.
Sacral nerve stimulation induces pan-colonic propagating pressure waves and increases
defaecation frequency in patients with slow transit constipation. Colorectal Dis 2007; 9(2):123-
32
52. Yan TD, Chu F, Black D, King DW, Morris DL
Synchronous Resection of Colorectal Primary Cancer and Liver Metastases
World J Surg (2007) 31:1496-1501
53. Nielsen HJ, Brunner N, Frederiksen C, Lomholt AF, King DW, Jorgensen LN, Olsen J, Rahr HB,
Thygesen K, Hoyer U, Laurgerb S, Christensen IJ
Plasma tissue inhibitor of metalloproteinases-1 (TIMP-1): A novel biological marker in the
detection of primary colorectal cancer. Protocol outlines of the Danish-Australian endoscopy
study group on colorectal cancer detection
22
Scandinavian Journal of Gastrolenterology (2007) (accepted for publication)
54. Mackey P, King D, Lubowski D
Post-anal repair. Do the long-term results justify the procedure?
Colorectal Disease 2008 (accepted for publication)
55. Burcher E, Shang F, Warner FJ, Du Q, Lubowski DZ, King DW, Liu L
Tachykinin NK2 receptor and functional mechanisms in human colon: changes with
indomethacin and in diverticualr disease and ulcerative colitis.
J Pharmacol Exp Ther. 2008 324:170-178
56. Liu L, Markus I, El Saghire H, Perera D, King D, Burcher E
Tachykinin gene expression in human smooth muscle and mucosa: disctinct differences in
ulcerative colitis, Crohn’s disease and diverticular disease.
American Journal of Physiology (accepted for publication 18Nov09)
57. Liu L, Shang F, Morgan MT, King DW, Lubowski DZ, Burcher E.
Cyclooxygenase-dependent alterations in substance P-mediated contractility and NKI receptor
expression in the colonic circular muscle of patients with slow transit constipation
J Pharmacol Exp Ther. 2009 329:282-289
58. Dinning PG, Jones M, Fuentealba SE, Kalanter K, King DW, Lubowski DZ, Talley NJ, Cook IJ.
Factor analysis identifies subgroups of constipation. World J Gastroenterol. 2011. 17(11): 1468-
74
23
Review Articles:
1. Lubowski D Z, King D W.
Faecal Incontinence. The National Continence Newsletter, Continence Foundation, No.
VAW8179, pp14, 1991
2. Lubowski D Z, King D W, Lam T C F.
Surgical management of anal incontinence.
Annals Academy of Med, Singapore 1992; 21:280-283
Monographs and Book Chapters:
1. Brooke B N, Cave D A, Gurry J F, King D W.
Crohn's Disease
Pub. Macmillans London 1976
2. Lam T C F, Lubowski D Z, King D W.
Solitary Rectal Ulcer Syndrome
In: Clinical Gastroenterology. Vol: Anorectal Disorders (Henry MM, Ed.)
Bailliere Tindall/ W B Saunders, London, 1992, Vol 6/1, pp129-143
3. Meagher A P, Adams W J, Lubowski D Z, King D W.
Anatomy of Rectum and Anus.
In: Colorectal Physiology: Fecal Incontinence (Kuijpers H C, Ed.)
CRC Press, Florida, 1994
4. King DW
Colorectal Cancer
In: Cancer: A Comprehensive Clinical Guide (Morris et al, Ed)
Harwood Academic Publishers, 1998
24
Publications – Abstracts/Letters:
1. King D W, Lubowski D Z, Bruck C E.
Do patients with haemorrhoids have pelvic floor denervation?
Aust NZ J Surg 1988; 58:243
2. Lubowski D Z, King D W, Bruck C E.
Do patients with haemorrhoids have pelvic floor denervation?
Br J Surg 1988; 75:1269-1270
3. McLean R, Gaston-Parry D, Smart R, Barbagallo S, Baker J, Lyons N, King D W, Lubowski D Z.
Oral In-111 DTPA: Its value for routine clinical assessment of colon transit.
J Nuclear Med 1989; 30:887
4. McLean R, Gaston-Parry D, Smart R, Barbagallo S, Baker J, Lyons N, King D W, Lubowski D Z.
Colon transit in health and constipation assessed using I-131 cellulose.
J Nuclear Med 1989; 30:764-765
5. Smart R, McLean R, Willson J, Barbagallo S, Gaston-Parry D, Lyons N, Lubowski D Z, King D W,
Bruck C E.
Colon transit in health and constipation: analysis using colon activity-profiles.
ANZ J Med 1990; Suppl 1:445
6. Smart R, McLean R, Wilson J, Barbagallo S, Gaston-Parry D, Lyons N, Lubowski D Z, King D W,
Bruck C E.
The assessment of colon transit in adults using In-111 DTPA and colon activity profiles.
Europ J Nuclear Med 1990; 16(suppl):S319
7. McLean R, Smart R, Lubowski D Z, King D W, Bruck C E.
Colon transit scintigraphy - normal ranges and variability in normal subjects.
ANZ J Med 1991; 21:633
8. McLean R, Smart R, Lubowski D Z, King D W, Stein P.
Colon transit scintigraphy in idiopathic constipation - can scan patterns predict pathology?
ANZ J Med 1991; 21:633
9. Lubowski D Z, King D W, McLean R G, Smart R, Gaston-Parry D.
Oral In-111 DTPA scintigraphy: its value for assessment of colon transit in severe constipation.
ANZ J Surg 1991;
10. McLean R G, Smart R C, Lubowski D Z, King D W, Bruck C E.
Colon transit scintigraphy: normal ranges and variability in normal subjects.
Aust NZ Soc Nucl Med 1991; 67
11.Adams WJ, King DW, Lubowski DZ, Morris DL
Cimetidine prevents postoperative suppression of immune function following colorectal cancer
surgery
25
Gut 1994; 35:S16
12. Young C, Kennedy M, Lubowski DZ, King DW
Postanal repair for faecal incontinence - long-term results
J Gastroenterol Hepatol 1994; 9:A113
13. Lubowski DZ, Kennedy M, King DW
Chemical sphincterotomy for anal fissure - a new treatment
Aus NZ J Surg 1995; 65:423
14. Adams WJ, Meagher AP, Lubowski DZ, King DW
Bisacodyl reduces the volume of polyethylene glycol solution required for bowel preparation
Gastroenterol Digest, May 1995; 15-16
15. Stewart GJ, Preketes AP, Lubowski DZ, King DW, Morris DL
Colorectal cancer response to high-dose sandostatin therapy: A clinical trial
Aust NZ J Surg 1995; 65:435
16. Burcher E, Warner FJ, Shang F, Markus I, Liu L, King DW, Lubowski DZ
Characterisation and autoradiographic localisation of tachykinin receptors in human colon
3rd
Australian Peptide Conference – From discovery to Therapeutics; Oct 1998
17. Burcher E, Warner FJ, Shang F, Markus I, Liu L, King DW, Lubowski DZ
Tachykinins in the human colon
Western Pharm Soc Maui, USA; Feb 1999
18. Dinning PG, Bampton PA, Andre J, Kennedy ML, Lubowski DZ, King DW, Cook IJ.
Constipation due to obstuted defaecation is likely to be a colonic rather than an ano-rectal
disorder.
Gastroenterology 2001:125(5)(Supl1);A751. (Presented American Gastroenterological
Association cinference, Atlanta May 2001)
19. Dinning PG, Bampton PA, Kennedy ML, Lubowski DZ, King DW, Cook IJ
Heightened rectal sensory thresholds and blunted recto-colonic motor reflexes implicated in
constipation due to obstructed defaecation.
Gastroenterology 2002; 122(4) A316. (Poster presentation at AGA Conference, San Francisco,
May 2002)
20. Azriel Y, Grimm M, Lubowski DZ, King DW, Burcher E.
Alterations in neurotensin receptors and responsiveness in slow transit constipation
AHMR Melbourne, Dec 2002; Proc Aust Health Med Res Congress 2002
21. Thornton MJ, Kennedy ML, Lubowski DZ, King DW
Long-term follow-up of Dynamic Graciloplasty for Faecal Incontinence
Am J Gastroenterology 2003;29(9 suppl) S1-339
22. Thornton MJ, Kennedy ML, King DW, Lubowski DZ.
26
The high frequency wave form (fast wave) in the hypertonic internal anal sphincter: validation
of a new observation.
Am J Gastroenterology 2003;29(9 suppl) S1-339
23. Cosman D, Thornton MJ, Cross KM, King DW, Morris DL.
Hepatic metastasis from colorectal cancer: analysis of morbidity and mortality of synchronous
treatment.
Am J Gastroenterology 2003;29 (9 suppl) S1-339
24. Thornton MJ, Kennedy ML, King DW
Botulinum Toxin for chronic anal fissure: prospective manometric assessment of 60 patients.
Colorectal Dis 2004;6(suppl 1):30
25. Thornton MJ, Kennedy ML, King DW
Botulinum Toxin for chronic anal fissure: prospective manometric assessment of 60 patients
ANZ J Surg 2004; 74 (Suppl) A34-A41 (CR21)
26. Thornton MJ, Kennedy ML, Lubowski DZ, King DW
Long-term follow-up of Dynamic Graciloplasty for Faecal Incontinence
ANZ J Surg 2004; 74 (Suppl) A30-A41 (CR 25)
27. Thornton MJ, Kennedy ML, Lubowski DZ, King DW
Long-term follow-up of Dynamic Graciloplasty for Faecal Incontinence
Colorectal Dis 2004;6(suppl 1):68 (P096)
Am J Gastroenterology 2003;29 (9suppl) S1-339
28. Phan-Thien K-C, Perera DS, King DW
Patient Compliance with Recall Colonoscopies – What is Good Enough?
ANZ J Surg. 2004; 74 (Suppl) A35
29. Thornton MJ, Lam A, King DW
Laparoscopic or transanal repair of rectocele? A retrospective matched cohort study.
ANZ J Surg 2004;74 (Suppl) A30-A41 (CR 42P)
30. Thornton MJ, Kennedy ML, King DW, Lubowski DZ.
The high frequency wave form (fast wave) in the hypertonic internal anal sphincter: validation
of a new observation.
Colorectal Dis 2004;6(suppl 1):69 (P098)
31. Thornton MJ, Kennedy ML, King DW, Lubowski DZ.
The high frequency wave form (fast wave) in the hypertonic internal anal sphincter: validation
of a new observation.
J Gastroenterology & Hepatology 2004;18(suppl):B44
32. Thornton MJ, Kennedy ML, King DW, Lubowski DZ.
27
The high frequency wave form (fast wave) in the hypertonic internal anal sphincter: validation
of a new observation.
ANZ J Surg 2004; 74 (Suppl) A30-A41 (CR 41P)
Am J Gastroenterology 2003;29 (9suppl) S1=339
33. Burns HL, Thornton MJ, King DW.
Pre-existing pelvic floor dysfunction prior to transanal rectocele repair: a retrospective analysis.
ANZ J Surg 2004;74 (suppl) A30-A41 (CR 52P)
34. Thornton MJ, Cross KM, King DW, Lubowski DZ, Morris DL.
Assessment of the value of the pre-operative abdominal CT in colorectal cancer.
J Gastroenterology & Hepatology 2004;18(suppl):A B4
35. Saafan AK, Thornton MJ, Gebski V, King DW.
The prevalence of diverticular disease in patients with slow transit constipation.
J Gastroenterology & Hepatology 2003;18(auppl):A B42
Am J Gastroenterology 2004;29 (9 suppl) S1-339
36. Byrne CM, Perera DS, King DW
Does rectal washout during anterior resection prevent local tumour recurrence?
Dis Colon Rectum 2005;48L172-4
37.Thornton MJ, Lam AM, King DW.
Bowel, bladder and sexual function in women undergoing laparoscopic posterior compartment
repair in the presence of apical or anterior compartment dysfunction.
Aust N Z J Obstet Gynaecol. 2005;45:195-200
28
Research Grants obtained:
NHMRC grant 157134. 2001-2003. Associate Investigator
Motor patterns of colonic transit and pathophysiology of severe constipation.
NHMRC grant 222739. 2002-2005. Associate Investigator
Neurochemicals and neuromodulators in human intestine: changes in disease.
NHMRC 568861. 2009-2011. Associate investigator
Hemokinin – a new inflammatory mediator in the intestine
Postgraduate students supervised:
M J Thornton: MD (UNSW) 2005 – Benign Anorectal Disorders
V Patton: PhD (UNSW) 2010 – Constipation and Incontinence
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