personalized therapy for cardiovascular disease

Mariana Velásquez CanoMedicine Student

Third semester

Dalcetapib provides benefits for those who are suceptible to have heart attacks, strokes, unstable

angina, coronary revascularizations, cardiovascular deaths and curbing ateriosclerosis.

This study have determinated how the somiking of tobacco and consuming high fat food, will

induced a mutation that can promote cancer.

Patients had to be with a genetic background to seek the correct

gene that promotes the desease.

The study showed that Dalcetrapib

will be a perzonalized

cardiovasculary medicine.

The 39% represents the reduction of the risk factors to own in the future

one of this desease.

The study aims to the Most common heart illneses that cause

death in the world.

Placebo was used to verified the efficiency of

dalcetrapib in any kind of patient, because placebo doesn’ t have any

chemist.

The investigators found the gene

(ADCY9 (adenylate cyclase

9) on chromosome 16,

through the result of the

medicament.

Must people that suffers from

cardiovascular desease is

predisposed to have

aterosclerosis, the first cause of mortality in the

world. With dalcetrapib , the probably to get

it is lower.

This study will lead to a

genetics-guided clinical study in

patients with cardiovasculaty

desease.

Smoking could lead to a damaged

on the DNA, causing a

mutacion, as cancer.

This type of genetic mutation

involves chemical

changes in the structure of

DNA.

Adducts are types of DNA that result from exposure to carcinogens.

In this case, the people who are

exposed to tobacco and consuming

foods such as cured meats will have a damaged in DNA,

.This study is an advange

of a possibility to expand DNA

sequencing including adducts.

The procedure of finding out where the

genetic code has been

altered into an adduct is

difficult and it has not been

possible.

They made a negative copy of the genetic

material as a analogous to study

how DNA is replicated in naturally

cells.They produced

artificial derivatives of the basic DNA building blocks to

tested them as potential

counterparts to the alkylguanine. 

We can use DNA

investigations, to prevent, act, trate and cure.

Is a base of a new

generation of discoveries

that will saved lives.

Have a tratement for any disease exactly where

patients need it.

Now that we know the cause and where is the

gene, we will know how to trate cancer and prevent it.

• ·Montreal Heart Institute. Personalized therapy for cardiovascular disease. ScienceDaily  [Internet] 2015 Jan [Fecha de acceso 22 enero  de 2015]. Disponible en: www.sciencedaily.com/releases/2015/01/1500112181327,htm

• ETH Zurich. Damaged DNA amplified by activities such as smoking. ScienceDaily  [Internet] 2015 Jan [Fecha de acceso 22 enero  de 2015]. Disponible en: www.sciencedaily.com/releases/2015/01/150115102833.htm

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