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PEPTIDES

2

Amino acid: Basic unit of protein

Peptide: 2 or more amino acids

Oligopeptide: 2 to 10 amino acids

Polypeptide: 11 to 50 amino acids

Protein: more than 51 amino acids

Amino acid, Peptide, Protein

Amino

acidPeptide Protein

3

• Protein molecules are large and cannot be absorbed

directly into the body

• It is digested into amino acids before absorbed by body

• But, amino acids can only be absorbed individually

• Peptide is absorbed in the form of a combination of

several amino acids

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Small Molecular Active Peptide

Let people 20 years younger and prolong

lifespan for 30 years

Peptides are extremely active and diverse,

superior to any nutrients and drugs!!

Leading the nutrition revolution of 21st century

Peptide is the energy key of cells

Types of Peptide

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Soy Oligopeptide

Balsam Pear Peptide

Corn Peptide

Walnut Peptide

Pea Peptide Rice Peptide

Wheat Peptide

Ovalbumin Peptide

Sea Cucumber Peptide

Salmon Ovary Peptide

SOY OLIGOPEPTIDE

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1

- Comprehensive Protection -

SOY OLIGOPEPTIDE

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Soy proteinProtease hydrolyse

Concentrate

SterilizationSpray Drying

Packaging

SOY OLIGOPEPTIDE

A) Weight Management

o Increase basal metabolic rate

o Promote decomposition and combustion of fats

o Increase energy consumption

o Reduce the risk of obesity

o Reduce the body's ability to store fat

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SOY OLIGOPEPTIDE

B) Skin Care

o Lighten skin spots and dark circles

o Promote skin cell regeneration

o Increase collagen and elastin synthesis

o Reduce signs of premature skin aging

Tighten skin, improve fine lines and wrinkles, smoothen and shine skin

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Soy Oligopeptide can protect human skin against UV B-induced

photodamage.

SOY OLIGOPEPTIDE

C) Reduce Muscle Fatigue

o Our action comes from muscle contraction

o Muscle / body fatigue performance will decline

o Stimulate secretion of growth hormone

o Relieve and reduce muscle protein breakdown

o Reduce muscle damage

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SOY OLIGOPEPTIDE

D) Maintain & Improve Brain Function

o Increase neuroactive amino acids

o Enhance neurological function

o Promote recovery of brain injury

o Improve forgetfulness

o Relieve cognitive decline due to aging

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Soy Oligopeptides as neuroprotective agents

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Soy Oligopeptide modulates the levels of neuroactive amino acids

in adult brain of mice.

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Soy oligopeptides

show antioxidant

and antihypertensive

effect in animal

studies

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Various functional properties of Soy Oligopeptide.

Comprehensive Protecting Peptide

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From China

<1000 Dalton

Application: Enhance overall health and physical fitness

Selling Point: Dissolve instantly and completely, brain

protective, strengthen immune system

BALSAM PEAR PEPTIDE

- Hypoglycemic -19

2

- Hypoglycemic -

BALSAM PEAR PEPTIDE

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• Hypoglycemic Peptide

• Saponins

• Polysaccharide

Dry

Bitter Gourd

(Momordica charantia) Biological Enzyme

Cutting Technique

BALSAM PEAR PEPTIDEA) Hypoglycemic Activity o Improve glucose tolerance of diabetic patient

o Activate insulin receptors on cell

o Glucose entered and metabolized by cells as energy

o Lower blood glucose level

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Mice with balsam pear peptide show reduced blood glucose level

after 2 hours and 4 hours of consumption.

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Balsam pear peptide not only reduced blood glucose level, the

glucose level is even lower than the original level after 2 hours.

BALSAM PEAR PEPTIDEB) Hypolipidemic activity o Decrease cholesterol and fatty acid synthesis

o Decrease concentration of triglyceride

o Decrease low-density lipoprotein (LDL) cholesterol

o Reduce incidence of heart disease

o Prevent arteriosclerosis and muscle atrophy

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Mice with balsam pear peptide has lower TC and LDL-C level but

higher HDL-C level.

Hypoglycemic Balsam Pear Peptide

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From China

<2000 Dalton

Application: Reduce blood glucose and cholesterol

Selling Point: For diabetes prevention and improvement

CORN PEPTIDE

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3

- Hepatoprotective -

CORN PEPTIDE

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Dried Powder

Corn

Modern Biological Compound

Enzyme Gradient Digestion

Three Grade Purification

Spray drying

Corn Peptide

CORN PEPTIDEA) Liver Protectingo Alcohol intake increases triglycerides amount in blood

o Triglyceride oxidized into malondialdehyde, which damage liver

o Corn peptide reduce triglyceride and malondialdehyde level

o Enhance metabolic function of liver cells

o Reduce alcohol-induced damage

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Results after 30 days

consumption

Consuming corn peptide lowered triglycerides and malondialdehyde

level, and the effect increased with concentration.

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Glutathione (GSH) is an antioxidant, protecting cells from ROS damage.

Consumption of corn peptide after 30 days increase GSH content.

Results after 30 days

consumption

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B) Sober up, Reduce intoxicationo Increase tolerance to alcohol

o Remain waken for a longer time before drunk

o Shorten the time drunk after alcohol intake

o Able to sober up in shorter time frame

o Good to take one hour before drinking alcohol

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CORN PEPTIDE

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In rats experiment, ingesting corn peptide shows longer tolerance

time to alcohol and shorter duration of drunk.

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Photo shows the liver membrane

screening of mice from different

groups. Corn Peptide effectively

reduced lipid damage on mice’s

liver membrane in a dose-

dependent manner.

White areas indicate damage

area.

TAA: thioacetamide

CP: corn peptide

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Corn peptide reduced uprising of blood ethanol after alcohol intake,

thereby longer the waken time before drunk.

Hepatoprotective Corn Peptide

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Other benefits: Lower blood pressure, Anti-oxidation

From China

<1000 Dalton

Application: Liver protecting and enhancing

Selling Point: Reduce damage from alcohol, increase

alcohol tolerance

WALNUT PEPTIDE

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4

- Neuroenhancement -

Walnut Peptide

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Smash, Defat Walnut Kernel

Walnut Dreg

Walnut Peptide

Oil, Enzyme

Solution Process

Spray Drying into

Powder

Walnut PeptideA) Improve Brain Functiono Contain L-arginine, the only amino acid involve in brain metabolism

o Increase nitric oxide which relax and smooth blood vessel muscle

o Cause vasodilation, more blood flow to brain and whole body

o Improve brain alertness, concentration, cognitive skill and memory

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Higher walnut peptide dosage generated more Nitric oxide in brain,

improved the learning and memory of mice.

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B) Anti-oxidationo Protect brain from oxidative damage

o Manage emotion, relieve depression and stress

o Anti-aging

o Improve physical fitness

o Anti-fatigue, accelerate body recovery

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Walnut Peptide

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Free radicals removal rate of walnut peptide increased with dosage

and was higher than Vitamin C at certain concentration.

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Anti-oxidation properties of walnut peptide can reverse sleep

deprivation-induced memory impairment, is a potential nutraceutical

against neurodegenerative disorders.

Neuro-Enhancing Walnut Peptide

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From China

<2000 Dalton

Application: Brain protecting and enhancing

Selling Point: New in market, Improve brain function,

prevent brain damage

PEA PEPTIDE

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5

- Intestinal Guardian -

Green Pea

Pea Protein

Pea Peptide

Pea Peptide

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Extraction

Modern Biological

Enzymolysis Technology,

Purification

A) Promote intestinal health o Promote growth of intestinal probiotics

o Inhibit growth of pathogens in intestine

o Balance and regulate intestinal flora

o Enhance immune cells activities

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Pea Peptide

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Pea peptide significantly promote the growth of Lactobacillus rhamnosus

and Lactobacillus acidophilus.

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Control

Pea Protein

Extract

Pea Protein Hydrolysate

Pea protein hydrolysate and extract stimulated adhesion of Total

bacterial number (TBN) and Lactobacillus (LAB) bacteria but not

Escherichia (EC) when compared to control.

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The glycated pea proteins affected the growth of gut commensal

bacteria, particularly Lactobacilli and Bifidobacteria, whose levels

increased significantly.

B) Boost immunityo Anti-bacteria, anti-inflammatory

o Alleviate inflammation symptoms and pain

o Possess immunomodulating function

o Strengthen overall health

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Pea Peptide

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Pea protein isolate (PPI) and pea protein hydrolysate (PPH) inhibit

the effect of pro-inflammatory cytokines (TNF-a and IL-6) and the

inhibitory effect is dose-dependent.

Anti-inflammatory Effect

Intestine Protecting Pea Peptide

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From China

<2000 Dalton

Application: Enhancing intestinal health and immunity

Selling Point: As intestine prebiotics, immunity booster

RICE PEPTIDE

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6

- Pressure Stabilizer -

Rice

Rice Protein

Rice Peptide

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Rice Peptide

Extraction

Modern Biological

Engineering Complex

Enzyme Gradient Cutting

Technology

Rice Peptide

A) Promote Cardiovascular Health o Prevent end of blood vessel shrinking

o Promote microcirculation

o Assimilate and reduce cholesterol

o Promote fat metabolism

o Reduce blood pressure

o Prevent cardiovascular disease

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Rice peptide significantly reduce the systolic blood pressure in essential

hypertension rats and inhibited the left ventricular hypertrophy. Rice

peptide in normal control group without antihypertensive effect

(Essential Hypertension Rats) (Normal Control Group)

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Rice peptide is anti-hypertensive and reduce blood pressure effectively.

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Rice peptides were

demonstrated to

possess

antioxidation,

antihypertensive,

anti-tyrosinase and

anti-inflammatory

activities.

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Rice peptides exert anti-oxidation, anti-diabetic, anti-cancer and ACE

inhibitory activities, which may prevent chronic diseases..

Pressure Stabilizing Rice Peptide

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From China

<2000 Dalton

Application: Reduce cholesterol and blood pressure

Selling Point: New in market, Improve cardiovascular health

WHEAT PEPTIDE

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7

- Body Energizer -

WheatWheat Protein

Wheat Peptide

Wheat Peptide

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Extraction Gradient Composite

Enzyme Cutting,

Multistage Separation

Purification

A) Enhance Exercise Capacityo Contain glutamic acid which is important for muscle cells

o Promote protein synthesis in muscle cells

o Promote growth and differentiation of muscle cells

o Increase physical strength and endurance

o Promote the repair of skeletal muscle cells

o Anti-fatigue

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Wheat Peptide

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Wheat peptide could effectively improve the ability of one-time

exhaustive exercise of rats, remove free radicals from skeletal muscle

and alleviate the intestinal and blood inflammatory responses.

B) Regulate immune functionso Contain glutamic acid which is important for mental

health as “chemical messenger”

o Promote proliferation of T lymphocytes

o Increase antibody levels in body fluids

o Enhance macrophage function

o Enhance activity of NK cells

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Wheat Peptide

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Wheat peptide effectively increased the immune function of rats by

increasing the multiplication of spleen lymphocytes.

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C) Intestinal Cell Regeneration

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Wheat Peptide

Wheat peptide promoted the growth of gastric mucosal epithelial cells,

which is reflected in a more neat arrangement, a tighter cell gap, and a

fuller morphology of epithelial cells.

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Wheat peptide promoted the growth of duodenal mucosal cells,

the surface epithelial cells are denser and more neatly

arranged epithelial cell morphology.

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Wheat peptide increased the activity of small intestinal mucosal

amino peptidase, indicating better absorption and utilization of protein.

Body Energizing Wheat Peptide

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From China

<1000 Dalton

>25% glutamic acid

Application: Enhancing physical strength and immunity

Selling Point: New in market, supply glutamine, immunity

booster

OVALBUMIN PEPTIDE

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8

- Cell Nourishment -

Egg White Ovalbumin Peptide

Ovalbumin Peptide

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Gradient Composite

Enzyme Cutting,

Multistage Separation

Purification

A) Immunologic Enhancemento Retain bioactivity components in ovalbumin

o Promote the nucleoside absorption

o Strengthen body immune system

o Stimulate growth of intestinal flora

o Stimulate activity of immune cells

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Ovalbumin Peptide

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Effect of ovalbumin peptide on phagocytosis of macrophages in

mice by intragastric administration after 30 days.

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Effect of ovalbumin peptide on NK cell activity in mice by

intragastric administration after 30 days.

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B) Improve Sleeping Qualityo Prolong pentobarbital (brain) sleeping time

o Improve quality of sleep

o Shorten time to fall asleep

o Aid in brain rest and refreshment

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Ovalbumin Peptide

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Ovalbumin peptide prolonged the sleeping time of mice.

SEA CUCUMBER PEPTIDE

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9

- Fatigue reducer-

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Sea cucumber peptide

Sea cucumber

protein

Sea cucumber

Extraction

Evaporation concentration

Spray drying

Refine

Sea Cucumber Peptide

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Sea Cucumber Peptide

A) Anti – Fatigue

o Synthesis of liver glycogen

o Reduce blood urea nitrogen

o Reduce blood lactic acid

o Improve exercise endurance

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The above experiment results show that sea cucumber peptide can

significantly reduce its blood urea nitrogen content, and increase

glycogen content of mice after exercise. Sea Cucumber Peptide has

anti‐fatigue activity and it exerted its anti‐fatigue effect probably

through normalizing energy metabolism as well as alleviating oxidative

damage and inflammatory responses.

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Sea Cucumber Peptide

B) Lowering blood sugar

o Reduce serum glucose level

o Increase serum insulin level

o Activate glycogen synthesis

o Suppress gluconeogenesis

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The above experiment results show that the blood sugar

level in mice in sea cucumber peptide group significantly

lower compared to mice in model group, indicated sea

cucumber peptide has significant hypoglycemia effect.

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C) Immunoregulation

o Enhance innate immune responses in

macrophages

o Promote antitumor activity

o Suppress inflammatory responses

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The results above showed that the NK cell activity has been

improved after the dosage of sea cucumber peptide. The higher

the sea cucumber peptide dosage, the higher the activity of NK

cell in mice. It could be conclude that the effects of sea

cucumber peptide on immune function were significantly

enhanced.

SALMON OVARY PEPTIDE (NON-HALAL)

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10

- Anti-aging-

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SALMON OVARY PEPTIDE

• It is a peptide generated by enzyme-decomposing

the outer coat of waste ovary from Salmon to

produce salmon roes.

• The salmon used is a chum salmon (non-cultured

salmon that mainly goes back to Shibetsu Town).

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Salmon Ovary

Salmon Ovary Protein

Salmon Ovary Peptide

SALMON OVARY PEPTIDE

Extraction

Microfiltration

Ultrafiltration

Reverse Osmosis

Concentration

Freeze Drying

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SALMON OVARY PEPTIDE

DO YOU KNOW?

Provided higher

amount of nutrient

than placenta of other

animals.

Contained with

various beneficial

nutrients similar to

nutrients demanded

by our body.

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Salmon ovary peptide

contained higher amount of

amino acids than other

animals

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SALMON OVARY PEPTIDE

A)Anti – aging

o Rich in antioxidants to fight major signs of

aging such as wrinkles, blemishes and

sagging

o Aids in skin thickness, resilience and

elasticity

o Reduce skin pigmentation problem

o Skin whitening effect

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SOP – great antioxidant activity

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B) Weight loss

• Prevent fat accumulation

• Control weight gain without any

decrease in appetite

• Invokes fat metabolism

SALMON OVARY PEPTIDE

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The above experiment showed that it has been confirmed that

the consumption of SOP along with high fat food has positive

effects on "metabolic syndrome“.

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SALMON OVARY PEPTIDE

C) Liver protection

o Liver detoxification

o Protective effect

against liver cells

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The above experiment showed that BOTH AST & ALT

level of mice decreased after consuming Salmon Ovary

Peptide (SOP).

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SALMON OVARY PEPTIDE

C) Improve blood circulation

o Anti-hypertension

o Cleanses blood vessels

o Prevents fat deposition

o Prevent cholesterol

o Regulates blood sugar levels

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After taking SOP, the peripheral blood circulation has been improved.

Cell Nourishing Peptide

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From China

<1000 Dalton

Application: Enhancing brain health and immunity

Selling Point: New in market, boost immunity, aid in sleeping

Conclusion

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• Comprehensive protection Soy Peptide

• Hypoglycemic (blood glucose)Balsam Pear

• Hepatoprotective (liver)Corn

• Neuroenhancement (brain)Walnut

• Intestinal guardian (probiotics)Pea

• Blood pressure stabilizerRice

• Body energizer Wheat

• Cell nourishmentOvalbumin

• Fatigue reducerSea Cucumber

Peptide

• Anti - agingSalmon Ovary

Peptide

Multi Peptides Combination

- Double, Triple, Quadruple, Quintuple -

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Double Peptide Series

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Double Peptide Series

Triple Peptide Series

Triple Peptide Series

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Quadruple Peptide

Quintuple Peptide

Customize Peptide Product

Type of peptide

Number of peptide

Product function

Product effect

Product costing

114

Lead the trend,For better health

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