page 2 / 9 · nioxin cleanser system emergency telephone transportation (24 hr) chemtrec -...
Post on 13-Aug-2020
1 Views
Preview:
TRANSCRIPT
Revision Date: 26-Apr-2012 Version 1
Material Safety Data Sheet
Issuing Date: 26-Apr-2012
Recommended use Personal Beauty Care Product
Manufacturer The Procter & Gamble CompanySharon Woods Technical Center11510 Reed Hartman HighwayCincinnati OH 45202.
OSHA Regulatory Status This material is not considered hazardous by the OSHA Hazard Communication Standard(29 CFR 1910.1200)
1. PRODUCT AND COMPANY IDENTIFICATION
E-mail Address pgsds.im@pg.com.
WHMIS Not subject to WHMIS classification
Product Name
Uses advised against All other uses
Principle Routes of Exposure Eye contact. Skin contact.
Nioxin Cleanser System
Emergency telephone Transportation (24 HR)CHEMTREC - 1-800-424-9300(U.S./ Canada) or 1-703-527-3887Mexico toll free in country: 01-800-681-9531.
Product ID:
General Hazards This is a personal care or cosmetic product that is safe for consumers and other usersunder normal and reasonably foreseeable use
92061445
2. HAZARDS IDENTIFICATION
_____________________________________________________________________________________________
Synonyms Nioxin Cleanser System 1 (92061445) * Nioxin Cleanser 2 (92061451) * Nioxin Cleanser 3(99426531) * Nioxin Cleanser 4 (92046875) * Nioxin Cleanser 5 (99473379) * NioxinCleanser 6 (99473380)
Emergency Overview
Page 1 / 9
Irritating to eyes
_____________________________________________________________________________________________92061445 - Nioxin Cleanser System Revision Date: 26-Apr-2012
Suitable Extinguishing Media
Special protective equipment forfire-fighters
As in any fire, wear self-contained breathing apparatus and full protective gear.
Dry chemical, CO 2, water spray or alcohol-resistant foam.
Flash Point
Unsuitable Extinguishing Media No information available.
Not applicable
5. FIRE-FIGHTING MEASURES
Special Hazard None in particular
1 - 5
General advice No hazards which require special first aid measures. When symptoms persist or in all casesof doubt seek medical advice.
Laureth-3 3055-94-5
Eye contact Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Ifsymptoms persist, call a physician. Remove contact lenses, if present, after the first 5minutes, then continue rinsing.
0.1 - 1
Poly(oxy-1,2-ethanediyl),alpha-sulfo-omega-(dodecyloxy)-, sodium salt (1:1)
9004-82-4
Sodium hydroxide (Na(OH))
Skin contact If skin problems occur, discontinue use. If symptoms persist, call a physician.
1310-73-2 0.1 - 1
5 - 10
Ingestion Clean mouth with water and afterwards drink plenty of water.
Mentha Arvensis Oil 68917-18-0 0.1 - 1
Inhalation Not an expected route of exposure.
Sulfuric acid monododecyl ester sodium salt (1:1)
1,2,3-Propanetriol 56-81-5 < 0.1
Protection of First-aiders Use personal protective equipment.
151-21-3 3 - 7
3. COMPOSITION/INFORMATION ON INGREDIENTS
Chemical Name
Most important symptoms/effects,acute and delayed
None known.
1-Propanaminium,3-amino-N-(carboxymethyl)-N,N-dimethyl-, N-coco
acyl derivs., inner salts
61789-40-0 1 - 5
CAS-No
Notes to physician Treat symptomatically.
4. FIRST AID MEASURES
Weight %
_____________________________________________________________________________________________
Citric acid
Page 2 / 9
77-92-9
_____________________________________________________________________________________________Revision Date: 26-Apr-201292061445 - Nioxin Cleanser System
Exposure Guidelines
Technical measures/Storageconditions
Keep out of the reach of children. Keep container tightly closed in a dry and well-ventilatedplace.
Engineering Measures Not applicable
Advice on safe handling
Chemical Name
Personal Protective Equipment
ACGIH TLV OSHA PEL NIOSH IDLH Mexico OEL
Eye Protection No special protective equipment required.
Keep out of the reach of children. Observe label precautions.
Sodium hydroxide(Na(OH))
Ceiling: 2 mg/m3
Hand Protection No special protective equipment required.
TWA: 2 mg/m3
(vacated) Ceiling: 2 mg/m3
IDLH: 10 mg/m3
Ceiling: 2 mg/m3
Mexico: Ceiling 2 mg/m3
Skin and body protection No special protective equipment required.
8. EXPOSURE CONTROLS/PERSONAL PROTECTION
1,2,3-Propanetriol TWA: 10 mg/m3 mist TWA: 15 mg/m3 mist, totalparticulate TWA: 5 mg/m3
mist, respirable fraction(vacated) TWA: 10 mg/m3
mist, total particulate(vacated) TWA: 5 mg/m3
mist, respirable fraction
Respiratory protection No special protective equipment required
Mexico: TWA 10 mg/m3
Thermal hazards Not applicable.
Chemical Name British Columbia Alberta Quebec
Hygiene measures Avoid contact with skin, eyes and clothing.
Ontario TWAEV
Sodium hydroxide(Na(OH))
Environmental Exposure Controls No special environmental precautions required.
Ceiling: 2 mg/m3 Ceiling: 2 mg/m3 Ceiling: 2 mg/m3 CEV: 2 mg/m3
7. HANDLING AND STORAGE
1,2,3-Propanetriol TWA: 10 mg/m3 TWA: 3mg/m3
TWA: 10 mg/m3 TWA: 10 mg/m3 TWA: 10 mg/m3
Personal precautions
Advice for emergency responders Use personal protective equipment.
Methods for Containment No information available.
None under normal use conditions.
_____________________________________________________________________________________________
6. ACCIDENTAL RELEASE MEASURES
Methods for Cleaning up No information available.
Page 3 / 9
Environmental precautions Should not be released into the environment.
_____________________________________________________________________________________________Revision Date: 26-Apr-201292061445 - Nioxin Cleanser System
Chemical Name logPow
9. PHYSICAL AND CHEMICAL PROPERTIES
Sulfuric acid monododecyl ester sodium salt (1:1) 1.6Citric acid -1.72 at 20 °C
Appearance
Dodecanol (Alcohol C12) 5.361,2,3-Propanetriol -1.76VOC Content Products comply with US state and federal regulations for VOC content in consumer
products.
viscous liquidblue (cleansers 1 -4)clear (cleansers 5, 6)
10. STABILITY AND REACTIVITY
Reactivity None under normal use conditions.
Stability Stable under normal conditions.
Hazardous Polymerization Hazardous polymerization does not occur.
Physical State @20°C
Odor
Hazardous Reactions None under normal processing.
Conditions to Avoid None under normal processing.
Mint-like, Fruity
Materials to Avoid None in particular.
Hazardous Decomposition Products None under normal use.
liquid
.
Boiling point/boiling range
Soluble in water
.
Vapor pressure
Viscosity of Product
.
.
Values
No information available
Not applicable
No information available
Solubility in other solvents
.
pH VALUE
Flammability (solid, gas)
.
Bulk Density
No information available
upper flammability limit
Not applicable 100 °C
No information available
.
Vapor density
.
No information available
Partition coefficient: n-octanol/water
No information available
Note
Not applicable
No information available
.
.
.
.Evaporation rate
.
Autoignition temperature
Relative density
lower flammability limit
No information available
Property
1.0
Flammability Limits in Air
.
Melting/freezing point
No information available
.
_____________________________________________________________________________________________
No information available
Decomposition temperature
Flash Point
4.6 - 5.2
Page 4 / 9
Water solubility
No information available
_____________________________________________________________________________________________92061445 - Nioxin Cleanser System Revision Date: 26-Apr-2012
Eye contact Irritating to eyes.
Sensitization No known effect.
Inhalation
Neurological Effects No known effect.Reproductive Toxicity The product contains no substances known to be hazardous to health in concentrations
which need to be taken into account.
No known effect based on information supplied.
Mutagenic Effects There are no known mutagenic chemicals in this product.Developmental Toxicity No known effect.Teratogenicity No known effect.
Principle Routes of Exposure Eye contact. Skin contact.
Carcinogenicity Contains no ingredients above reportable quantities listed as a carcinogen.
Skin contact No known effect based on information supplied.
11. TOXICOLOGICAL INFORMATION
Ingestion
Chronic Toxicity
_____________________________________________________________________________________________
No known effect based on information supplied.
Acute Toxicity
Page 5 / 9
Corrosivity No known effect.
_____________________________________________________________________________________________Revision Date: 26-Apr-201292061445 - Nioxin Cleanser System
EC50 48 h = 1.8 mg/LDaphnia magna
= 53 mg/L EC50 30 -100 mg/L EC50 = 117
mg/L EC50 3.59 -15.6 mg/L EC50
-
Acute Toxicity
1-Propanaminium,3-amino-N-(carboxymethyl)-N,N-dimethyl-, N-coco acyl
derivs., inner salts
EC50 72 h 1.0 - 10.0mg/L Desmodesmussubspicatus EC50 96
h = 0.55 mg/LDesmodesmus
subspicatus
LC50 96 h 1.0 - 10.0mg/L Brachydaniorerio LC50 96 h = 2mg/L Brachydaniorerio semi-static
- EC50 48 h = 6.5 mg/LDaphnia magna
1.0 - 10.0 mg/L EC50= 0.55 mg/L EC50
-
Citric acid - LC50 96 h = 1516mg/L Lepomis
macrochirus static
- EC50 72 h = 120 mg/LDaphnia magna
-
12. ECOLOGICAL INFORMATION
Chemical Name Toxicity to algae Toxicity to fish Toxicity tomicroorganisms
_____________________________________________________________________________________________
Toxicity to daphniaand other aquatic
invertebrates
Toxicity to otherorganisms
Ecotoxicity
Page 6 / 9
Sulfuric acid monododecylester sodium salt (1:1)
EC50 72 h = 53 mg/LDesmodesmus
subspicatus EC50 96h 30 - 100 mg/LDesmodesmus
subspicatus EC50 96h = 117 mg/L
Pseudokirchneriellasubcapitata EC50 96 h
3.59 - 15.6 mg/LPseudokirchneriellasubcapitata static
LC50 96 h 8 - 12.5mg/L Pimephales
promelas static LC5096 h 15 - 18.9 mg/L
Pimephales promelasstatic LC50 96 h 22.1
- 22.8 mg/LPimephales promelasstatic LC50 96 h 4.3 -
8.5 mg/LOncorhynchus mykiss
static LC50 96 h =4.62 mg/L
Oncorhynchus mykissflow-through LC50 96
h = 4.2 mg/LOncorhynchus mykissLC50 96 h = 7.97 mg/L
Brachydanio rerioflow-through LC50 96
h 9.9 - 20.1 mg/LBrachydanio rerio
semi-static LC50 96 h4.06 - 5.75 mg/L
Lepomis macrochirusstatic LC50 96 h 4.2 -
4.8 mg/L Lepomismacrochirus
flow-through LC50 96h = 4.5 mg/L Lepomismacrochirus LC50 96
h 5.8 - 7.5 mg/LPimephales promelasstatic LC50 96 h 10.2
- 22.5 mg/LPimephales promelassemi-static LC50 96 h
6.2 - 9.6 mg/LPimephales promelasLC50 96 h 13.5 - 18.3
mg/L Poeciliareticulata semi-static
LC50 96 h 10.8 - 16.6mg/L Poecilia
reticulata static LC5096 h = 1.31 mg/LCyprinus carpio
semi-static
-
_____________________________________________________________________________________________Revision Date: 26-Apr-201292061445 - Nioxin Cleanser System
15. REGULATORY INFORMATION
14. TRANSPORT INFORMATION
MEX
U.S. Federal Regulations
Not regulated
DOT
SARA 313Section 313 of Title III of the Superfund Amendments and Reauthorization Act of 1986 (SARA). This product does not contain anychemicals which are subject to the reporting requirements of the Act and Title 40 of the Code of Federal Regulations, Part 372.
Not regulated
IATA
SARA 311/312 Hazard Categories
Not regulated
Acute Health Hazard noChronic Health Hazard noFire Hazard no
ICAO Not regulated
TDG Not regulated
IMDG/IMO Not regulated
Sodium hydroxide (Na(OH)) -
Persistence and degradability No information available.
Dodecanol (Alcohol C12) EC50 96 h = 0.62mg/L Desmodesmus
subspicatus
LC50 96 h = 1.01 mg/LPimephales promelasflow-through LC50 96
h = 0.1855 mg/LPimephales promelas
13. DISPOSAL CONSIDERATIONS
-
Bioaccumulative potential No information available.
EC50 48 h = 320 mg/LDaphnia magna
= 0.62 mg/L EC50
-
Waste from Residues / UnusedProducts
Household: Do not discharge product into natural waters without pre-treatment oradequate dilution.
LC50 96 h = 45.4 mg/LOncorhynchus mykiss
static
-
Contaminated packaging Dispose of in accordance with local regulations.
1,2,3-Propanetriol -
Mobility No information available.
LC50 96 h 51 - 57mL/L Oncorhynchus
mykiss static
- EC50 24 h > 500 mg/LDaphnia magna
-
_____________________________________________________________________________________________
- -
Other adverse effects
Page 7 / 9
No information available
_____________________________________________________________________________________________92061445 - Nioxin Cleanser System Revision Date: 26-Apr-2012
Chemical Name Pennsylvania
Sudden Release of Pressure Hazard
Sulfuric acid sodium salt (1:2) X
Sodium hydroxide (Na(OH))
Chemical Name
Sodium hydroxide (Na(OH)) X
CWA - ReportableQuantities
CWA - Toxic Pollutants CWA - Priority Pollutants CWA - HazardousSubstances
1000 lb -
International Regulations
Sodium hydroxide(Na(OH))
1000 lb - -
Canada
X
RQ 1000 lb final RQ RQ 454 kgfinal RQ
WHMIS Hazard ClassNot subject to WHMIS classification
U.S. State Regulations
CERCLAThis material, as supplied, contains one or more substances regulated as a hazardous substance under the ComprehensiveEnvironmental Response Compensation and Liability Act (CERCLA) (40 CFR 302):
This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations (CPR) and theMSDS contains all the information required by the CPR. This product is regulated by the Food and Drug Administration of HealthCanada and is therefore exempt from the requirements of CEPA.
Food and Drug Administration (FDA)The product described in this Material Safety Data Sheet is regulated under the Federal Food, Drug, and Cosmetics Act and is safeto use as per directions on container, box or accompanying literature (where applicable).
Reactive Hazard no
California Proposition 65This product is not subject to warning labeling under California Proposition 65
International Inventories
no
TSCA Exempt
Clean Air Act, Section 112 Hazardous Air Pollutants (HAPs) (see 40 CFR 61)This product does not contain any substances regulated as hazardous air pollutants (HAPS) under Section 112 of the Clean Air ActAmendments of 1990.
U.S. State Regulations
DSL Exempt
Chemical Name
NDSL Exempt
Hazardous Substances RQs
_____________________________________________________________________________________________
Extremely HazardousSubstances RQs
Clean Water ActThis product contains the following substances which are regulated pollutants pursuant to the Clean Water Act (40 CFR 122.21and 40 CFR 122.42):
Page 8 / 9
RQ
_____________________________________________________________________________________________Revision Date: 26-Apr-201292061445 - Nioxin Cleanser System
Legend
Perfumes contained with the products comply with appropriate IFRA guidance.
DSL/NDSL - Canadian Domestic Substances List/Non-Domestic Substances ListTSCA - United States Toxic Substances Control Act Section 8(b) Inventory
16. OTHER INFORMATION
Issuing Date:
DisclaimerThe information provided in this Safety Data Sheet is correct to the best of our knowledge, information and belief at the date of itspublication. The information given is designed only as a guidance for safe handling, use, processing, storage, transportation,disposal and release and is not to be considered a warranty or quality specification. The information relates only to the specificmaterial designated and may not be valid for such material used in combination with any other materials or in any process, unlessspecified in the text
_____________________________________________________________________________________________
26-Apr-2012
Page 9 / 9
Revision Date:
End of MSDS
26-Apr-2012
Issuing Date: 06-Jun-2012 Revision Date: 06-Jun-2012 Version 1
Material Safety Data Sheet
Recommended use Personal Beauty Care Product
Manufacturer
OSHA Regulatory Status Consumer Products as defined by the U.S. Consumer Product Safety Act which are usedas intended (typical consumer duration and frequency) are exempt from the OSHA HazardCommunication Standard
The Procter & Gamble CompanySharon Woods Innovation Center11510 Reed Hartman HighwayCincinnati OH 45202
WHMIS Not subject to WHMIS classification
1. PRODUCT AND COMPANY IDENTIFICATION
E-mail Address pgsds.im@pg.com
Principle Routes of Exposure Skin contact. Eye contact.
Product Name
Uses advised against All other uses
General Hazards This is a personal care or cosmetic product that is safe for consumers and other usersunder normal and reasonably foreseeable use
Nioxin Scalp Therapy 1
Emergency telephone Transportation (24 HR)CHEMTREC - 1-800-424-9300(U.S./ Canada) or 1-703-527-3887Mexico toll free in country: 01-800-681-9531
Product ID:
_____________________________________________________________________________________________
92245785
2. HAZARDS IDENTIFICATION
Page 1 / 9
Synonyms System 1 Conditioner
Emergency Overview
_____________________________________________________________________________________________92245785 - Nioxin Scalp Therapy 1 Revision Date: 06-Jun-2012
Suitable Extinguishing Media
Special protective equipment forfire-fighters
As in any fire, wear self-contained breathing apparatus and full protective gear.
Dry chemical, CO 2, water spray or alcohol-resistant foam.
Flash Point
Unsuitable Extinguishing Media No information available.
No information available
5. FIRE-FIGHTING MEASURES
Special Hazard None in particular
1 - 5Quaternary ammonium compounds,
bis(hydrogenated tallow alkyl)dimethyl, chlorides
Inhalation Not an expected route of exposure.
4. FIRST AID MEASURES
61789-80-8 0.1 - 1
Protection of First-aiders Use personal protective equipment.
3. COMPOSITION/INFORMATION ON INGREDIENTS
Chemical Name
Most important symptoms/effects,acute and delayed
None known.
General advice No hazards which require special first aid measures. When symptoms persist or in all casesof doubt seek medical advice.
Mentha Arvensis Oil 68917-18-0
Notes to physician Treat symptomatically.
0.1 - 1
CAS-No
Eye contact Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Ifsymptoms persist, call a physician. Remove contact lenses, if present, after the first 5minutes, then continue rinsing.
Weight %
glycerol 1-stearate 123-94-4 0.1 - 1
Skin contact
_____________________________________________________________________________________________
If skin problems occur, discontinue use. If symptoms persist, call a physician.
Page 2 / 9
Octadecanamide, N-[3-(dimethylamino)propyl]- 7651-02-7
Ingestion Clean mouth with water and afterwards drink plenty of water.
_____________________________________________________________________________________________Revision Date: 06-Jun-201292245785 - Nioxin Scalp Therapy 1
Advice on safe handling
Chemical Name
Eye Protection No special protective equipment required.
ACGIH TLV OSHA PEL NIOSH IDLH Mexico OEL
Hand Protection No special protective equipment required.
Keep out of the reach of children. Observe label precautions.
glycerol 1-stearate TWA: 10 mg/m3 exceptstearates of toxic metals
Skin and body protection No special protective equipment required.
- -
Respiratory protection No special protective equipment required
8. EXPOSURE CONTROLS/PERSONAL PROTECTION
Chemical Name British Columbia Alberta
Thermal hazards Not applicable.
Quebec Ontario TWAEV
Hygiene measures None under normal use condtions.
glycerol 1-stearate TWA: 10 mg/m3 TWA: 10 mg/m3 -
Environmental Exposure Controls See Section 6.
TWA: 10 mg/m3
7. HANDLING AND STORAGE
Engineering Measures Not applicable.
Exposure Guidelines
Technical measures/Storageconditions
Keep out of the reach of children. Keep containers tightly closed in a dry, cool andwell-ventilated place.
Personal Protective Equipment
Environmental precautions Should not be released into the environment.
Personal precautions
Advice for emergency responders Use personal protective equipment.
Methods for Containment
_____________________________________________________________________________________________
No information available.
Use personal protective equipment.
Page 3 / 9
6. ACCIDENTAL RELEASE MEASURES
Methods for Cleaning up No information available.
_____________________________________________________________________________________________Revision Date: 06-Jun-201292245785 - Nioxin Scalp Therapy 1
VOC Content Products comply with US state and federal regulations for VOC content in consumerproducts.
9. PHYSICAL AND CHEMICAL PROPERTIES
Appearance
10. STABILITY AND REACTIVITY
blue. viscous liquid .
Reactivity None under normal use conditions.
Stability Stable under normal conditions.
Hazardous Polymerization Hazardous polymerization does not occur.
Hazardous Reactions None under normal processing.
Conditions to Avoid None under normal processing.
Physical State @20°C
Odor
Materials to Avoid None in particular.
Hazardous Decomposition Products None under normal use.
Mint-like
liquid
No information available
Property
0.96
Flammability Limits in Air
.
Melting/freezing point
No information available
No information available
Decomposition temperature
Flash Point
5
Water solubility
No information available .
Boiling point/boiling range
No information available
Vapor pressure
Viscosity of Product
Values
No information available
No information available
No information available
Solubility in other solvents
pH VALUE
Flammability (solid, gas)
Bulk Density
No information available
upper flammability limit
No information availableNo information available
No information available
Vapor density
No information available
Partition coefficient: n-octanol/water
No information available
Note
No information available
No information available
_____________________________________________________________________________________________
Evaporation rate
Page 4 / 9
Autoignition temperature
Relative density
lower flammability limit
_____________________________________________________________________________________________Revision Date: 06-Jun-201292245785 - Nioxin Scalp Therapy 1
1240 mg/kg ( Rat ) 5 g/kg ( Rabbit ) -
Skin contact No known effect based on information supplied.
Chronic Toxicity
11. TOXICOLOGICAL INFORMATION
Ingestion
Corrosivity No known effect.
No known effect based on information supplied.
Sensitization No known effect.
Principle Routes of Exposure
Neurological Effects No known effect.
Eye contact No known effect based on information supplied.
Reproductive Toxicity The product contains no substances known to be hazardous to health in concentrationswhich need to be taken into account.
Skin contact. Eye contact.
Mutagenic Effects There are no known mutagenic chemicals in this product.Developmental Toxicity No known effect.
Product Information
Teratogenicity No known effect.Carcinogenicity Contains no ingredients above reportable quantities listed as a carcinogen.
Acute Toxicity Product does not present an acute toxicity hazard based on known or supplied information.
Inhalation
Chemical Name LD50 Oral LD50 Dermal LC50 Inhalation
No known effect based on information supplied.
_____________________________________________________________________________________________
Quaternary ammoniumcompounds, bis(hydrogenatedtallow alkyl)dimethyl, chlorides
2000 mg/kg ( Rat ) 2000 mg/kg ( Rat )
Page 5 / 9
180 mg/L ( Rat ) 1 h
Mentha Arvensis Oil
_____________________________________________________________________________________________92245785 - Nioxin Scalp Therapy 1 Revision Date: 06-Jun-2012
Packing Group IIIDescription UN3082, Environmentally hazardous substance, liquid, n.o.s (Quaternary ammonium
compounds, bis(hydrogenated tallow alkyl)dimethyl, chlorides, Mentha Arvensis Oil), 9, III,
TDG
MEX UN/ID No UN3082Proper shipping name Environmentally hazardous substances, liquid, n.o.s.
UN/ID No UN3082
Hazard class 9
14. TRANSPORT INFORMATION
Packing Group III
Proper shipping name ENVIRONMENTALLY HAZARDOUS SUBSTANCE, LIQUID, N.O.S.
DOT
Hazard class 9
Not regulated
Toxicity to otherorganisms
Waste from Residues / UnusedProducts
Dispose of in accordance with local regulations.
Chemical Name Bioconcentration factor (BCF)
Ecotoxicity
Contaminated packaging Dispose of in accordance with local regulations.
Quaternary ammonium compounds, bis(hydrogenated tallow alkyl)dimethyl,chlorides
13
Quaternary ammoniumcompounds,
bis(hydrogenated tallowalkyl)dimethyl, chlorides
EC50 96 h = 0.1 mg/LDesmodesmus
subspicatus EC50 72h = 0.00046 mg/L
Pseudokirchneriellasubcapitata
LC50 96 h = 1.48 mg/LBrachydanio rerio
static
-
Mobility No information available.
EC50 48 h = 0.32mg/L Daphnia magna
= 0.1 mg/L EC50 =0.00046 mg/L EC50
-
Acute Toxicity
Other adverse effects No information available
Persistence and degradability No information available.
12. ECOLOGICAL INFORMATION
Chemical Name Toxicity to algae
Bioaccumulative potential
13. DISPOSAL CONSIDERATIONS
No information available.
_____________________________________________________________________________________________
Toxicity to fish Toxicity tomicroorganisms
Page 6 / 9
Toxicity to daphniaand other aquatic
invertebrates
_____________________________________________________________________________________________92245785 - Nioxin Scalp Therapy 1 Revision Date: 06-Jun-2012
UN3082, Environmentally hazardous substance, liquid, n.o.s (Quaternary ammoniumcompounds, bis(hydrogenated tallow alkyl)dimethyl, chlorides, Mentha Arvensis Oil), 9, III
Packing Group III
UN3082, Environmentally hazardous substance, liquid, n.o.s (Quaternary ammoniumcompounds, bis(hydrogenated tallow alkyl)dimethyl, chlorides, Mentha Arvensis Oil), 9, III,
EmS No. F-A, S-FDescription UN3082, Environmentally hazardous substance, liquid, n.o.s (Quaternary ammonium
compounds, bis(hydrogenated tallow alkyl)dimethyl, chlorides, Mentha Arvensis Oil), 9, III,
Proper shipping name
ICAO
ENVIRONMENTALLY HAZARDOUS SUBSTANCE, LIQUID, N.O.S.
15. REGULATORY INFORMATIONU.S. Federal Regulations
UN/ID No UN3082
IATA
SARA 313Section 313 of Title III of the Superfund Amendments and Reauthorization Act of 1986 (SARA). This product does not contain anychemicals which are subject to the reporting requirements of the Act and Title 40 of the Code of Federal Regulations, Part 372.
Proper shipping name ENVIRONMENTALLY HAZARDOUS SUBSTANCE, LIQUID, N.O.S.
Hazard class
SARA 311/312 Hazard Categories
9
Acute Health Hazard no
Hazard class 9
Chronic Health Hazard no
Description
Fire Hazard no
Packing Group
Sudden Release of Pressure Hazard no
III
Reactive Hazard no
Packing Group
Description UN3082, Environmentally hazardous substance, liquid, n.o.s (Quaternary ammoniumcompounds, bis(hydrogenated tallow alkyl)dimethyl, chlorides, Mentha Arvensis Oil), 9, III,
CERCLAThis material, as supplied, contains one or more substances regulated as a hazardous substance under the ComprehensiveEnvironmental Response Compensation and Liability Act (CERCLA) (40 CFR 302):
III
Chemical Name Hazardous Substances RQs Extremely HazardousSubstances RQs
RQ
Edetic acid 5000 lb - RQ 5000 lb final RQ RQ 2270kg final RQ
IMDG/IMO
Food and Drug Administration (FDA)The product described in this Material Safety Data Sheet is regulated under the Federal Food, Drug, and Cosmetics Act and is safeto use as per directions on container, box or accompanying literature (where applicable).
ERG Code 9L
UN/ID No
Clean Air Act, Section 112 Hazardous Air Pollutants (HAPs) (see 40 CFR 61)This product does not contain any substances regulated as hazardous air pollutants (HAPS) under Section 112 of the Clean Air ActAmendments of 1990.
UN3082
UN/ID No UN3082
_____________________________________________________________________________________________
Proper shipping name ENVIRONMENTALLY HAZARDOUS SUBSTANCE, LIQUID, N.O.S.
Page 7 / 9
Description
Hazard class 9
_____________________________________________________________________________________________Revision Date: 06-Jun-201292245785 - Nioxin Scalp Therapy 1
CWA - Toxic Pollutants
TSCA Exempt
Edetic acid
DSL Exempt
X
CWA - Priority Pollutants
NDSL Exempt
CWA - HazardousSubstances
Perfumes contained with the products comply with appropriate IFRA guidance.
California Proposition 65This product is not subject to warning labeling under California Proposition 65
Legend TSCA - United States Toxic Substances Control Act Section 8(b) Inventory
International Regulations
DSL/NDSL - Canadian Domestic Substances List/Non-Domestic Substances List
Edetic acid 5000 lb
U.S. State Regulations
Canada
- -
WHMIS Hazard ClassNot subject to WHMIS classification
X
Clean Water ActThis product contains the following substances which are regulated pollutants pursuant to the Clean Water Act (40 CFR 122.21and 40 CFR 122.42):
This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations (CPR) and theMSDS contains all the information required by the CPR. This product is regulated by the Food and Drug Administration of HealthCanada and is therefore exempt from the requirements of CEPA.
Chemical Name
U.S. State Regulations
International Inventories
CWA - ReportableQuantities
Chemical Name Pennsylvania
06-Jun-2012
16. OTHER INFORMATION
Issuing Date:
_____________________________________________________________________________________________
DisclaimerThe information provided in this Safety Data Sheet is correct to the best of our knowledge, information and belief at the date of itspublication. The information given is designed only as a guidance for safe handling, use, processing, storage, transportation,disposal and release and is not to be considered a warranty or quality specification. The information relates only to the specificmaterial designated and may not be valid for such material used in combination with any other materials or in any process, unlessspecified in the text
06-Jun-2012
Page 8 / 9
Revision Date:
End of MSDS
Issuing Date: 06-Jun-2012 Revision Date: 06-Jun-2012 Version 1
Material Safety Data Sheet
Recommended use Personal Beauty Care Product
Manufacturer
OSHA Regulatory Status Consumer Products as defined by the U.S. Consumer Product Safety Act which are usedas intended (typical consumer duration and frequency) are exempt from the OSHA HazardCommunication Standard
The Procter & Gamble CompanySharon Woods Innovation Center11510 Reed Hartman HighwayCincinnati OH 45202
WHMIS Not subject to WHMIS classification
1. PRODUCT AND COMPANY IDENTIFICATION
E-mail Address pgsds.im@pg.com
Principle Routes of Exposure Skin contact. Eye contact.
Product Name
Uses advised against All other uses
General Hazards This is a personal care or cosmetic product that is safe for consumers and other usersunder normal and reasonably foreseeable use
Nioxin Scalp Therapy 2
Emergency telephone Transportation (24 HR)CHEMTREC - 1-800-424-9300(U.S./ Canada) or 1-703-527-3887Mexico toll free in country: 01-800-681-9531
Product ID:
_____________________________________________________________________________________________
92245783
2. HAZARDS IDENTIFICATION
Page 1 / 9
Synonyms System 2 Conditioner
Emergency Overview
_____________________________________________________________________________________________92245783 - Nioxin Scalp Therapy 2 Revision Date: 06-Jun-2012
Suitable Extinguishing Media
Special protective equipment forfire-fighters
As in any fire, wear self-contained breathing apparatus and full protective gear.
Dry chemical, CO 2, water spray or alcohol-resistant foam.
Flash Point
Unsuitable Extinguishing Media No information available.
No information available
5. FIRE-FIGHTING MEASURES
Special Hazard None in particular
1 - 5Quaternary ammonium compounds,
bis(hydrogenated tallow alkyl)dimethyl, chlorides
Inhalation Not an expected route of exposure.
4. FIRST AID MEASURES
61789-80-8 0.1 - 1
Protection of First-aiders Use personal protective equipment.
3. COMPOSITION/INFORMATION ON INGREDIENTS
Chemical Name
Most important symptoms/effects,acute and delayed
None known.
General advice No hazards which require special first aid measures. When symptoms persist or in all casesof doubt seek medical advice.
glycerol 1-stearate 123-94-4
Notes to physician Treat symptomatically.
0.1 - 1
CAS-No
Eye contact Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Ifsymptoms persist, call a physician. Remove contact lenses, if present, after the first 5minutes, then continue rinsing.
Weight %
Mentha Arvensis Oil 68917-18-0 0.1 - 1
Skin contact
_____________________________________________________________________________________________
If skin problems occur, discontinue use. If symptoms persist, call a physician.
Page 2 / 9
Octadecanamide, N-[3-(dimethylamino)propyl]- 7651-02-7
Ingestion Clean mouth with water and afterwards drink plenty of water.
_____________________________________________________________________________________________Revision Date: 06-Jun-201292245783 - Nioxin Scalp Therapy 2
Advice on safe handling
Chemical Name
Eye Protection No special protective equipment required.
ACGIH TLV OSHA PEL NIOSH IDLH Mexico OEL
Hand Protection No special protective equipment required.
Keep out of the reach of children. Observe label precautions.
glycerol 1-stearate TWA: 10 mg/m3 exceptstearates of toxic metals
Skin and body protection No special protective equipment required.
- -
Respiratory protection No special protective equipment required
8. EXPOSURE CONTROLS/PERSONAL PROTECTION
Chemical Name British Columbia Alberta
Thermal hazards Not applicable.
Quebec Ontario TWAEV
Hygiene measures None under normal use condtions.
glycerol 1-stearate TWA: 10 mg/m3 TWA: 10 mg/m3 -
Environmental Exposure Controls See Section 6.
TWA: 10 mg/m3
7. HANDLING AND STORAGE
Engineering Measures Not applicable.
Exposure Guidelines
Technical measures/Storageconditions
Keep out of the reach of children. Keep containers tightly closed in a dry, cool andwell-ventilated place.
Personal Protective Equipment
Environmental precautions Should not be released into the environment.
Personal precautions
Advice for emergency responders Use personal protective equipment.
Methods for Containment
_____________________________________________________________________________________________
No information available.
Use personal protective equipment.
Page 3 / 9
6. ACCIDENTAL RELEASE MEASURES
Methods for Cleaning up No information available.
_____________________________________________________________________________________________Revision Date: 06-Jun-201292245783 - Nioxin Scalp Therapy 2
VOC Content Products comply with US state and federal regulations for VOC content in consumerproducts.
9. PHYSICAL AND CHEMICAL PROPERTIES
Appearance
10. STABILITY AND REACTIVITY
viscous liquid .
Reactivity None under normal use conditions.
Stability Stable under normal conditions.
Hazardous Polymerization Hazardous polymerization does not occur.
Hazardous Reactions None under normal processing.
Conditions to Avoid None under normal processing.
Physical State @20°C
Odor
Materials to Avoid None in particular.
Hazardous Decomposition Products None under normal use.
Mint-like
liquid
No information available
Property
0.96
Flammability Limits in Air
.
Melting/freezing point
No information available
No information available
Decomposition temperature
Flash Point
5
Water solubility
No information available .
Boiling point/boiling range
No information available
Vapor pressure
Viscosity of Product
Values
No information available
No information available
No information available
Solubility in other solvents
pH VALUE
Flammability (solid, gas)
Bulk Density
No information available
upper flammability limit
No information availableNo information available
No information available
Vapor density
No information available
Partition coefficient: n-octanol/water
No information available
Note
No information available
No information available
_____________________________________________________________________________________________
Evaporation rate
Page 4 / 9
Autoignition temperature
Relative density
lower flammability limit
_____________________________________________________________________________________________Revision Date: 06-Jun-201292245783 - Nioxin Scalp Therapy 2
1240 mg/kg ( Rat ) 5 g/kg ( Rabbit ) -
Skin contact No known effect based on information supplied.
Chronic Toxicity
11. TOXICOLOGICAL INFORMATION
Ingestion
Corrosivity No known effect.
No known effect based on information supplied.
Sensitization No known effect.
Principle Routes of Exposure
Neurological Effects No known effect.
Eye contact No known effect based on information supplied.
Reproductive Toxicity The product contains no substances known to be hazardous to health in concentrationswhich need to be taken into account.
Skin contact. Eye contact.
Mutagenic Effects There are no known mutagenic chemicals in this product.Developmental Toxicity No known effect.
Product Information
Teratogenicity No known effect.Carcinogenicity Contains no ingredients above reportable quantities listed as a carcinogen.
Acute Toxicity Product does not present an acute toxicity hazard based on known or supplied information.
Inhalation
Chemical Name LD50 Oral LD50 Dermal LC50 Inhalation
No known effect based on information supplied.
_____________________________________________________________________________________________
Quaternary ammoniumcompounds, bis(hydrogenatedtallow alkyl)dimethyl, chlorides
2000 mg/kg ( Rat ) 2000 mg/kg ( Rat )
Page 5 / 9
180 mg/L ( Rat ) 1 h
Mentha Arvensis Oil
_____________________________________________________________________________________________92245783 - Nioxin Scalp Therapy 2 Revision Date: 06-Jun-2012
Packing Group IIIDescription UN3082, Environmentally hazardous substance, liquid, n.o.s (Quaternary ammonium
compounds, bis(hydrogenated tallow alkyl)dimethyl, chlorides, Mentha Arvensis Oil), 9, III,
TDG
MEX UN/ID No UN3082Proper shipping name Environmentally hazardous substances, liquid, n.o.s.
UN/ID No UN3082
Hazard class 9
14. TRANSPORT INFORMATION
Packing Group III
Proper shipping name ENVIRONMENTALLY HAZARDOUS SUBSTANCE, LIQUID, N.O.S.
DOT
Hazard class 9
Not regulated
Toxicity to otherorganisms
Waste from Residues / UnusedProducts
Dispose of in accordance with local regulations.
Chemical Name Bioconcentration factor (BCF)
Ecotoxicity
Contaminated packaging Dispose of in accordance with local regulations.
Quaternary ammonium compounds, bis(hydrogenated tallow alkyl)dimethyl,chlorides
13
Quaternary ammoniumcompounds,
bis(hydrogenated tallowalkyl)dimethyl, chlorides
EC50 96 h = 0.1 mg/LDesmodesmus
subspicatus EC50 72h = 0.00046 mg/L
Pseudokirchneriellasubcapitata
LC50 96 h = 1.48 mg/LBrachydanio rerio
static
-
Mobility No information available.
EC50 48 h = 0.32mg/L Daphnia magna
= 0.1 mg/L EC50 =0.00046 mg/L EC50
-
Acute Toxicity
Other adverse effects No information available
Persistence and degradability No information available.
12. ECOLOGICAL INFORMATION
Chemical Name Toxicity to algae
Bioaccumulative potential
13. DISPOSAL CONSIDERATIONS
No information available.
_____________________________________________________________________________________________
Toxicity to fish Toxicity tomicroorganisms
Page 6 / 9
Toxicity to daphniaand other aquatic
invertebrates
_____________________________________________________________________________________________92245783 - Nioxin Scalp Therapy 2 Revision Date: 06-Jun-2012
UN3082, Environmentally hazardous substance, liquid, n.o.s (Quaternary ammoniumcompounds, bis(hydrogenated tallow alkyl)dimethyl, chlorides, Mentha Arvensis Oil), 9, III
Packing Group III
UN3082, Environmentally hazardous substance, liquid, n.o.s (Quaternary ammoniumcompounds, bis(hydrogenated tallow alkyl)dimethyl, chlorides, Mentha Arvensis Oil), 9, III,
EmS No. F-A, S-FDescription UN3082, Environmentally hazardous substance, liquid, n.o.s (Quaternary ammonium
compounds, bis(hydrogenated tallow alkyl)dimethyl, chlorides, Mentha Arvensis Oil), 9, III,
Proper shipping name
ICAO
ENVIRONMENTALLY HAZARDOUS SUBSTANCE, LIQUID, N.O.S.
15. REGULATORY INFORMATIONU.S. Federal Regulations
UN/ID No UN3082
IATA
SARA 313Section 313 of Title III of the Superfund Amendments and Reauthorization Act of 1986 (SARA). This product does not contain anychemicals which are subject to the reporting requirements of the Act and Title 40 of the Code of Federal Regulations, Part 372.
Proper shipping name ENVIRONMENTALLY HAZARDOUS SUBSTANCE, LIQUID, N.O.S.
Hazard class
SARA 311/312 Hazard Categories
9
Acute Health Hazard no
Hazard class 9
Chronic Health Hazard no
Description
Fire Hazard no
Packing Group
Sudden Release of Pressure Hazard no
III
Reactive Hazard no
Packing Group
Description UN3082, Environmentally hazardous substance, liquid, n.o.s (Quaternary ammoniumcompounds, bis(hydrogenated tallow alkyl)dimethyl, chlorides, Mentha Arvensis Oil), 9, III,
CERCLAThis material, as supplied, contains one or more substances regulated as a hazardous substance under the ComprehensiveEnvironmental Response Compensation and Liability Act (CERCLA) (40 CFR 302):
III
Chemical Name Hazardous Substances RQs Extremely HazardousSubstances RQs
RQ
Edetic acid 5000 lb - RQ 5000 lb final RQ RQ 2270kg final RQ
IMDG/IMO
Food and Drug Administration (FDA)The product described in this Material Safety Data Sheet is regulated under the Federal Food, Drug, and Cosmetics Act and is safeto use as per directions on container, box or accompanying literature (where applicable).
ERG Code 9L
UN/ID No
Clean Air Act, Section 112 Hazardous Air Pollutants (HAPs) (see 40 CFR 61)This product does not contain any substances regulated as hazardous air pollutants (HAPS) under Section 112 of the Clean Air ActAmendments of 1990.
UN3082
UN/ID No UN3082
_____________________________________________________________________________________________
Proper shipping name ENVIRONMENTALLY HAZARDOUS SUBSTANCE, LIQUID, N.O.S.
Page 7 / 9
Description
Hazard class 9
_____________________________________________________________________________________________Revision Date: 06-Jun-201292245783 - Nioxin Scalp Therapy 2
CWA - Toxic Pollutants
TSCA Exempt
Edetic acid
DSL Exempt
X
CWA - Priority Pollutants
NDSL Exempt
CWA - HazardousSubstances
Perfumes contained with the products comply with appropriate IFRA guidance.
California Proposition 65This product is not subject to warning labeling under California Proposition 65
Legend TSCA - United States Toxic Substances Control Act Section 8(b) Inventory
International Regulations
DSL/NDSL - Canadian Domestic Substances List/Non-Domestic Substances List
Edetic acid 5000 lb
U.S. State Regulations
Canada
- -
WHMIS Hazard ClassNot subject to WHMIS classification
X
Clean Water ActThis product contains the following substances which are regulated pollutants pursuant to the Clean Water Act (40 CFR 122.21and 40 CFR 122.42):
This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations (CPR) and theMSDS contains all the information required by the CPR. This product is regulated by the Food and Drug Administration of HealthCanada and is therefore exempt from the requirements of CEPA.
Chemical Name
U.S. State Regulations
International Inventories
CWA - ReportableQuantities
Chemical Name Pennsylvania
06-Jun-2012
16. OTHER INFORMATION
Issuing Date:
_____________________________________________________________________________________________
DisclaimerThe information provided in this Safety Data Sheet is correct to the best of our knowledge, information and belief at the date of itspublication. The information given is designed only as a guidance for safe handling, use, processing, storage, transportation,disposal and release and is not to be considered a warranty or quality specification. The information relates only to the specificmaterial designated and may not be valid for such material used in combination with any other materials or in any process, unlessspecified in the text
06-Jun-2012
Page 8 / 9
Revision Date:
End of MSDS
Issuing Date: 06-Jun-2012 Revision Date: 06-Jun-2012 Version 1
Material Safety Data Sheet
Recommended use Personal Beauty Care Product
Manufacturer
OSHA Regulatory Status Consumer Products as defined by the U.S. Consumer Product Safety Act which are usedas intended (typical consumer duration and frequency) are exempt from the OSHA HazardCommunication Standard
The Procter & Gamble CompanySharon Woods Innovation Center11510 Reed Hartman HighwayCincinnati OH 45202
WHMIS Not subject to WHMIS classification
1. PRODUCT AND COMPANY IDENTIFICATION
E-mail Address pgsds.im@pg.com
Principle Routes of Exposure Skin contact. Eye contact.
Product Name
Uses advised against All other uses
General Hazards This is a personal care or cosmetic product that is safe for consumers and other usersunder normal and reasonably foreseeable use
Nioxin Scalp Therapy 3
Emergency telephone Transportation (24 HR)CHEMTREC - 1-800-424-9300(U.S./ Canada) or 1-703-527-3887Mexico toll free in country: 01-800-681-9531
Product ID:
_____________________________________________________________________________________________
92245786
2. HAZARDS IDENTIFICATION
Page 1 / 9
Synonyms System 3 Conditioner
Emergency Overview
_____________________________________________________________________________________________92245786 - Nioxin Scalp Therapy 3 Revision Date: 06-Jun-2012
Suitable Extinguishing Media
Special protective equipment forfire-fighters
As in any fire, wear self-contained breathing apparatus and full protective gear.
Dry chemical, CO 2, water spray or alcohol-resistant foam.
Flash Point
Unsuitable Extinguishing Media No information available.
No information available
5. FIRE-FIGHTING MEASURES
Special Hazard None in particular
1 - 5Quaternary ammonium compounds,
bis(hydrogenated tallow alkyl)dimethyl, chlorides
Inhalation Not an expected route of exposure.
4. FIRST AID MEASURES
61789-80-8 0.1 - 1
Protection of First-aiders Use personal protective equipment.
3. COMPOSITION/INFORMATION ON INGREDIENTS
Chemical Name
Most important symptoms/effects,acute and delayed
None known.
General advice No hazards which require special first aid measures. When symptoms persist or in all casesof doubt seek medical advice.
Mentha Arvensis Oil 68917-18-0
Notes to physician Treat symptomatically.
0.1 - 1
CAS-No
Eye contact Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Ifsymptoms persist, call a physician. Remove contact lenses, if present, after the first 5minutes, then continue rinsing.
Weight %
glycerol 1-stearate 123-94-4 0.1 - 1
Skin contact
_____________________________________________________________________________________________
If skin problems occur, discontinue use. If symptoms persist, call a physician.
Page 2 / 9
Octadecanamide, N-[3-(dimethylamino)propyl]- 7651-02-7
Ingestion Clean mouth with water and afterwards drink plenty of water.
_____________________________________________________________________________________________Revision Date: 06-Jun-201292245786 - Nioxin Scalp Therapy 3
Advice on safe handling
Chemical Name
Eye Protection No special protective equipment required.
ACGIH TLV OSHA PEL NIOSH IDLH Mexico OEL
Hand Protection No special protective equipment required.
Keep out of the reach of children. Observe label precautions.
glycerol 1-stearate TWA: 10 mg/m3 exceptstearates of toxic metals
Skin and body protection No special protective equipment required.
- -
Respiratory protection No special protective equipment required
8. EXPOSURE CONTROLS/PERSONAL PROTECTION
Chemical Name British Columbia Alberta
Thermal hazards Not applicable.
Quebec Ontario TWAEV
Hygiene measures None under normal use condtions.
glycerol 1-stearate TWA: 10 mg/m3 TWA: 10 mg/m3 -
Environmental Exposure Controls See Section 6.
TWA: 10 mg/m3
7. HANDLING AND STORAGE
Engineering Measures Not applicable.
Exposure Guidelines
Technical measures/Storageconditions
Keep out of the reach of children. Keep containers tightly closed in a dry, cool andwell-ventilated place.
Personal Protective Equipment
Environmental precautions Should not be released into the environment.
Personal precautions
Advice for emergency responders Use personal protective equipment.
Methods for Containment
_____________________________________________________________________________________________
No information available.
Use personal protective equipment.
Page 3 / 9
6. ACCIDENTAL RELEASE MEASURES
Methods for Cleaning up No information available.
_____________________________________________________________________________________________Revision Date: 06-Jun-201292245786 - Nioxin Scalp Therapy 3
VOC Content Products comply with US state and federal regulations for VOC content in consumerproducts.
9. PHYSICAL AND CHEMICAL PROPERTIES
Appearance
10. STABILITY AND REACTIVITY
blue. viscous liquid .
Reactivity None under normal use conditions.
Stability Stable under normal conditions.
Hazardous Polymerization Hazardous polymerization does not occur.
Hazardous Reactions None under normal processing.
Conditions to Avoid None under normal processing.
Physical State @20°C
Odor
Materials to Avoid None in particular.
Hazardous Decomposition Products None under normal use.
Mint-like
liquid
No information available
Property
0.96
Flammability Limits in Air
.
Melting/freezing point
No information available
No information available
Decomposition temperature
Flash Point
5
Water solubility
No information available .
Boiling point/boiling range
No information available
Vapor pressure
Viscosity of Product
Values
No information available
No information available
No information available
Solubility in other solvents
pH VALUE
Flammability (solid, gas)
Bulk Density
No information available
upper flammability limit
No information availableNo information available
No information available
Vapor density
No information available
Partition coefficient: n-octanol/water
No information available
Note
No information available
No information available
_____________________________________________________________________________________________
Evaporation rate
Page 4 / 9
Autoignition temperature
Relative density
lower flammability limit
_____________________________________________________________________________________________Revision Date: 06-Jun-201292245786 - Nioxin Scalp Therapy 3
1240 mg/kg ( Rat ) 5 g/kg ( Rabbit ) -
Skin contact No known effect based on information supplied.
Chronic Toxicity
11. TOXICOLOGICAL INFORMATION
Ingestion
Corrosivity No known effect.
No known effect based on information supplied.
Sensitization No known effect.
Principle Routes of Exposure
Neurological Effects No known effect.
Eye contact No known effect based on information supplied.
Reproductive Toxicity The product contains no substances known to be hazardous to health in concentrationswhich need to be taken into account.
Skin contact. Eye contact.
Mutagenic Effects There are no known mutagenic chemicals in this product.Developmental Toxicity No known effect.
Product Information
Teratogenicity No known effect.Carcinogenicity Contains no ingredients above reportable quantities listed as a carcinogen.
Acute Toxicity Product does not present an acute toxicity hazard based on known or supplied information.
Inhalation
Chemical Name LD50 Oral LD50 Dermal LC50 Inhalation
No known effect based on information supplied.
_____________________________________________________________________________________________
Quaternary ammoniumcompounds, bis(hydrogenatedtallow alkyl)dimethyl, chlorides
2000 mg/kg ( Rat ) 2000 mg/kg ( Rat )
Page 5 / 9
180 mg/L ( Rat ) 1 h
Mentha Arvensis Oil
_____________________________________________________________________________________________92245786 - Nioxin Scalp Therapy 3 Revision Date: 06-Jun-2012
Packing Group IIIDescription UN3082, Environmentally hazardous substance, liquid, n.o.s (Quaternary ammonium
compounds, bis(hydrogenated tallow alkyl)dimethyl, chlorides, Mentha Arvensis Oil), 9, III
TDG
MEX UN/ID No UN3082Proper shipping name Environmentally hazardous substances, liquid, n.o.s.
UN/ID No UN3082
Hazard class 9
14. TRANSPORT INFORMATION
Packing Group III
Proper shipping name ENVIRONMENTALLY HAZARDOUS SUBSTANCE, LIQUID, N.O.S.
DOT
Hazard class 9
Not regulated
Toxicity to otherorganisms
Waste from Residues / UnusedProducts
Dispose of in accordance with local regulations.
Chemical Name Bioconcentration factor (BCF)
Ecotoxicity
Contaminated packaging Dispose of in accordance with local regulations.
Quaternary ammonium compounds, bis(hydrogenated tallow alkyl)dimethyl,chlorides
13
Quaternary ammoniumcompounds,
bis(hydrogenated tallowalkyl)dimethyl, chlorides
EC50 96 h = 0.1 mg/LDesmodesmus
subspicatus EC50 72h = 0.00046 mg/L
Pseudokirchneriellasubcapitata
LC50 96 h = 1.48 mg/LBrachydanio rerio
static
-
Mobility No information available.
EC50 48 h = 0.32mg/L Daphnia magna
= 0.1 mg/L EC50 =0.00046 mg/L EC50
-
Acute Toxicity
Other adverse effects No information available
Persistence and degradability No information available.
12. ECOLOGICAL INFORMATION
Chemical Name Toxicity to algae
Bioaccumulative potential
13. DISPOSAL CONSIDERATIONS
No information available.
_____________________________________________________________________________________________
Toxicity to fish Toxicity tomicroorganisms
Page 6 / 9
Toxicity to daphniaand other aquatic
invertebrates
_____________________________________________________________________________________________92245786 - Nioxin Scalp Therapy 3 Revision Date: 06-Jun-2012
UN3082, Environmentally hazardous substance, liquid, n.o.s (Quaternary ammoniumcompounds, bis(hydrogenated tallow alkyl)dimethyl, chlorides, Mentha Arvensis Oil), 9, III
Packing Group III
UN3082, Environmentally hazardous substance, liquid, n.o.s (Quaternary ammoniumcompounds, bis(hydrogenated tallow alkyl)dimethyl, chlorides, Mentha Arvensis Oil), 9, III
EmS No. F-A, S-FDescription UN3082, Environmentally hazardous substance, liquid, n.o.s (Quaternary ammonium
compounds, bis(hydrogenated tallow alkyl)dimethyl, chlorides, Mentha Arvensis Oil), 9, III
Proper shipping name
ICAO
ENVIRONMENTALLY HAZARDOUS SUBSTANCE, LIQUID, N.O.S.
15. REGULATORY INFORMATIONU.S. Federal Regulations
UN/ID No UN3082
IATA
SARA 313Section 313 of Title III of the Superfund Amendments and Reauthorization Act of 1986 (SARA). This product does not contain anychemicals which are subject to the reporting requirements of the Act and Title 40 of the Code of Federal Regulations, Part 372.
Proper shipping name ENVIRONMENTALLY HAZARDOUS SUBSTANCE, LIQUID, N.O.S.
Hazard class
SARA 311/312 Hazard Categories
9
Acute Health Hazard no
Hazard class 9
Chronic Health Hazard no
Description
Fire Hazard no
Packing Group
Sudden Release of Pressure Hazard no
III
Reactive Hazard no
Packing Group
Description UN3082, Environmentally hazardous substance, liquid, n.o.s (Quaternary ammoniumcompounds, bis(hydrogenated tallow alkyl)dimethyl, chlorides, Mentha Arvensis Oil), 9, III
CERCLAThis material, as supplied, contains one or more substances regulated as a hazardous substance under the ComprehensiveEnvironmental Response Compensation and Liability Act (CERCLA) (40 CFR 302):
III
Chemical Name Hazardous Substances RQs Extremely HazardousSubstances RQs
RQ
Edetic acid 5000 lb - RQ 5000 lb final RQ RQ 2270kg final RQ
IMDG/IMO
Food and Drug Administration (FDA)The product described in this Material Safety Data Sheet is regulated under the Federal Food, Drug, and Cosmetics Act and is safeto use as per directions on container, box or accompanying literature (where applicable).
ERG Code 9L
UN/ID No
Clean Air Act, Section 112 Hazardous Air Pollutants (HAPs) (see 40 CFR 61)This product does not contain any substances regulated as hazardous air pollutants (HAPS) under Section 112 of the Clean Air ActAmendments of 1990.
UN3082
UN/ID No UN3082
_____________________________________________________________________________________________
Proper shipping name ENVIRONMENTALLY HAZARDOUS SUBSTANCE, LIQUID, N.O.S.
Page 7 / 9
Description
Hazard class 9
_____________________________________________________________________________________________Revision Date: 06-Jun-201292245786 - Nioxin Scalp Therapy 3
CWA - Toxic Pollutants
TSCA Exempt
Edetic acid
DSL Exempt
X
CWA - Priority Pollutants
NDSL Exempt
CWA - HazardousSubstances
Perfumes contained with the products comply with appropriate IFRA guidance.
California Proposition 65This product is not subject to warning labeling under California Proposition 65
Legend TSCA - United States Toxic Substances Control Act Section 8(b) Inventory
International Regulations
DSL/NDSL - Canadian Domestic Substances List/Non-Domestic Substances List
Edetic acid 5000 lb
U.S. State Regulations
Canada
- -
WHMIS Hazard ClassNot subject to WHMIS classification
X
Clean Water ActThis product contains the following substances which are regulated pollutants pursuant to the Clean Water Act (40 CFR 122.21and 40 CFR 122.42):
This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations (CPR) and theMSDS contains all the information required by the CPR. This product is regulated by the Food and Drug Administration of HealthCanada and is therefore exempt from the requirements of CEPA.
Chemical Name
U.S. State Regulations
International Inventories
CWA - ReportableQuantities
Chemical Name Pennsylvania
06-Jun-2012
16. OTHER INFORMATION
Issuing Date:
_____________________________________________________________________________________________
DisclaimerThe information provided in this Safety Data Sheet is correct to the best of our knowledge, information and belief at the date of itspublication. The information given is designed only as a guidance for safe handling, use, processing, storage, transportation,disposal and release and is not to be considered a warranty or quality specification. The information relates only to the specificmaterial designated and may not be valid for such material used in combination with any other materials or in any process, unlessspecified in the text
06-Jun-2012
Page 8 / 9
Revision Date:
End of MSDS
Issuing Date: 06-Jun-2012 Revision Date: 06-Jun-2012 Version 1
Material Safety Data Sheet
Recommended use Personal Beauty Care Product
Manufacturer
OSHA Regulatory Status Consumer Products as defined by the U.S. Consumer Product Safety Act which are usedas intended (typical consumer duration and frequency) are exempt from the OSHA HazardCommunication Standard
The Procter & Gamble CompanySharon Woods Innovation Center11510 Reed Hartman HighwayCincinnati OH 45202
WHMIS Not subject to WHMIS classification
1. PRODUCT AND COMPANY IDENTIFICATION
E-mail Address pgsds.im@pg.com
Principle Routes of Exposure Skin contact. Eye contact.
Product Name
Uses advised against All other uses
General Hazards This is a personal care or cosmetic product that is safe for consumers and other usersunder normal and reasonably foreseeable use
Nioxin Scalp Therapy 4
Emergency telephone Transportation (24 HR)CHEMTREC - 1-800-424-9300(U.S./ Canada) or 1-703-527-3887Mexico toll free in country: 01-800-681-9531
Product ID:
_____________________________________________________________________________________________
92245784
2. HAZARDS IDENTIFICATION
Page 1 / 9
Synonyms System 4 Conditioner
Emergency Overview
_____________________________________________________________________________________________92245784 - Nioxin Scalp Therapy 4 Revision Date: 06-Jun-2012
Suitable Extinguishing Media
Special protective equipment forfire-fighters
As in any fire, wear self-contained breathing apparatus and full protective gear.
Dry chemical, CO 2, water spray or alcohol-resistant foam.
Flash Point
Unsuitable Extinguishing Media No information available.
No information available
5. FIRE-FIGHTING MEASURES
Special Hazard None in particular
1 - 5Quaternary ammonium compounds,
bis(hydrogenated tallow alkyl)dimethyl, chlorides
Inhalation Not an expected route of exposure.
4. FIRST AID MEASURES
61789-80-8 0.1 - 1
Protection of First-aiders Use personal protective equipment.
3. COMPOSITION/INFORMATION ON INGREDIENTS
Chemical Name
Most important symptoms/effects,acute and delayed
None known.
General advice No hazards which require special first aid measures. When symptoms persist or in all casesof doubt seek medical advice.
glycerol 1-stearate 123-94-4
Notes to physician Treat symptomatically.
0.1 - 1
CAS-No
Eye contact Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Ifsymptoms persist, call a physician. Remove contact lenses, if present, after the first 5minutes, then continue rinsing.
Weight %
Mentha Arvensis Oil 68917-18-0 0.1 - 1
Skin contact
_____________________________________________________________________________________________
If skin problems occur, discontinue use. If symptoms persist, call a physician.
Page 2 / 9
Octadecanamide, N-[3-(dimethylamino)propyl]- 7651-02-7
Ingestion Clean mouth with water and afterwards drink plenty of water.
_____________________________________________________________________________________________Revision Date: 06-Jun-201292245784 - Nioxin Scalp Therapy 4
Advice on safe handling
Chemical Name
Eye Protection No special protective equipment required.
ACGIH TLV OSHA PEL NIOSH IDLH Mexico OEL
Hand Protection No special protective equipment required.
Keep out of the reach of children. Observe label precautions.
glycerol 1-stearate TWA: 10 mg/m3 exceptstearates of toxic metals
Skin and body protection No special protective equipment required.
- -
Respiratory protection No special protective equipment required
8. EXPOSURE CONTROLS/PERSONAL PROTECTION
Chemical Name British Columbia Alberta
Thermal hazards Not applicable.
Quebec Ontario TWAEV
Hygiene measures None under normal use condtions.
glycerol 1-stearate TWA: 10 mg/m3 TWA: 10 mg/m3 -
Environmental Exposure Controls See Section 6.
TWA: 10 mg/m3
7. HANDLING AND STORAGE
Engineering Measures Not applicable.
Exposure Guidelines
Technical measures/Storageconditions
Keep out of the reach of children. Keep containers tightly closed in a dry, cool andwell-ventilated place.
Personal Protective Equipment
Environmental precautions Should not be released into the environment.
Personal precautions
Advice for emergency responders Use personal protective equipment.
Methods for Containment
_____________________________________________________________________________________________
No information available.
Use personal protective equipment.
Page 3 / 9
6. ACCIDENTAL RELEASE MEASURES
Methods for Cleaning up No information available.
_____________________________________________________________________________________________Revision Date: 06-Jun-201292245784 - Nioxin Scalp Therapy 4
VOC Content Products comply with US state and federal regulations for VOC content in consumerproducts.
9. PHYSICAL AND CHEMICAL PROPERTIES
Appearance
10. STABILITY AND REACTIVITY
blue. viscous liquid .
Reactivity None under normal use conditions.
Stability Stable under normal conditions.
Hazardous Polymerization Hazardous polymerization does not occur.
Hazardous Reactions None under normal processing.
Conditions to Avoid None under normal processing.
Physical State @20°C
Odor
Materials to Avoid None in particular.
Hazardous Decomposition Products None under normal use.
Mint-like
liquid
No information available
Property
0.96
Flammability Limits in Air
.
Melting/freezing point
No information available
No information available
Decomposition temperature
Flash Point
5
Water solubility
No information available .
Boiling point/boiling range
No information available
Vapor pressure
Viscosity of Product
Values
No information available
No information available
No information available
Solubility in other solvents
pH VALUE
Flammability (solid, gas)
Bulk Density
No information available
upper flammability limit
No information availableNo information available
No information available
Vapor density
No information available
Partition coefficient: n-octanol/water
No information available
Note
No information available
No information available
_____________________________________________________________________________________________
Evaporation rate
Page 4 / 9
Autoignition temperature
Relative density
lower flammability limit
_____________________________________________________________________________________________Revision Date: 06-Jun-201292245784 - Nioxin Scalp Therapy 4
1240 mg/kg ( Rat ) 5 g/kg ( Rabbit ) -
Skin contact No known effect based on information supplied.
Chronic Toxicity
11. TOXICOLOGICAL INFORMATION
Ingestion
Corrosivity No known effect.
No known effect based on information supplied.
Sensitization No known effect.
Principle Routes of Exposure
Neurological Effects No known effect.
Eye contact No known effect based on information supplied.
Reproductive Toxicity The product contains no substances known to be hazardous to health in concentrationswhich need to be taken into account.
Skin contact. Eye contact.
Mutagenic Effects There are no known mutagenic chemicals in this product.Developmental Toxicity No known effect.
Product Information
Teratogenicity No known effect.Carcinogenicity Contains no ingredients above reportable quantities listed as a carcinogen.
Acute Toxicity Product does not present an acute toxicity hazard based on known or supplied information.
Inhalation
Chemical Name LD50 Oral LD50 Dermal LC50 Inhalation
No known effect based on information supplied.
_____________________________________________________________________________________________
Quaternary ammoniumcompounds, bis(hydrogenatedtallow alkyl)dimethyl, chlorides
2000 mg/kg ( Rat ) 2000 mg/kg ( Rat )
Page 5 / 9
180 mg/L ( Rat ) 1 h
Mentha Arvensis Oil
_____________________________________________________________________________________________92245784 - Nioxin Scalp Therapy 4 Revision Date: 06-Jun-2012
Packing Group IIIDescription UN3082, Environmentally hazardous substance, liquid, n.o.s (Quaternary ammonium
compounds, bis(hydrogenated tallow alkyl)dimethyl, chlorides, Mentha Arvensis Oil), 9, III,
TDG
MEX UN/ID No UN3082Proper shipping name Environmentally hazardous substances, liquid, n.o.s.
UN/ID No UN3082
Hazard class 9
14. TRANSPORT INFORMATION
Packing Group III
Proper shipping name ENVIRONMENTALLY HAZARDOUS SUBSTANCE, LIQUID, N.O.S.
DOT
Hazard class 9
Not regulated
Toxicity to otherorganisms
Waste from Residues / UnusedProducts
Dispose of in accordance with local regulations.
Chemical Name Bioconcentration factor (BCF)
Ecotoxicity
Contaminated packaging Dispose of in accordance with local regulations.
Quaternary ammonium compounds, bis(hydrogenated tallow alkyl)dimethyl,chlorides
13
Quaternary ammoniumcompounds,
bis(hydrogenated tallowalkyl)dimethyl, chlorides
EC50 96 h = 0.1 mg/LDesmodesmus
subspicatus EC50 72h = 0.00046 mg/L
Pseudokirchneriellasubcapitata
LC50 96 h = 1.48 mg/LBrachydanio rerio
static
-
Mobility No information available.
EC50 48 h = 0.32mg/L Daphnia magna
= 0.1 mg/L EC50 =0.00046 mg/L EC50
-
Acute Toxicity
Other adverse effects No information available
Persistence and degradability No information available.
12. ECOLOGICAL INFORMATION
Chemical Name Toxicity to algae
Bioaccumulative potential
13. DISPOSAL CONSIDERATIONS
No information available.
_____________________________________________________________________________________________
Toxicity to fish Toxicity tomicroorganisms
Page 6 / 9
Toxicity to daphniaand other aquatic
invertebrates
_____________________________________________________________________________________________92245784 - Nioxin Scalp Therapy 4 Revision Date: 06-Jun-2012
UN3082, Environmentally hazardous substance, liquid, n.o.s (Quaternary ammoniumcompounds, bis(hydrogenated tallow alkyl)dimethyl, chlorides, Mentha Arvensis Oil), 9, III
Packing Group III
UN3082, Environmentally hazardous substance, liquid, n.o.s (Quaternary ammoniumcompounds, bis(hydrogenated tallow alkyl)dimethyl, chlorides, Mentha Arvensis Oil), 9, III,
EmS No. F-A, S-FDescription UN3082, Environmentally hazardous substance, liquid, n.o.s (Quaternary ammonium
compounds, bis(hydrogenated tallow alkyl)dimethyl, chlorides, Mentha Arvensis Oil), 9, III,
Proper shipping name
ICAO
ENVIRONMENTALLY HAZARDOUS SUBSTANCE, LIQUID, N.O.S.
15. REGULATORY INFORMATIONU.S. Federal Regulations
UN/ID No UN3082
IATA
SARA 313Section 313 of Title III of the Superfund Amendments and Reauthorization Act of 1986 (SARA). This product does not contain anychemicals which are subject to the reporting requirements of the Act and Title 40 of the Code of Federal Regulations, Part 372.
Proper shipping name ENVIRONMENTALLY HAZARDOUS SUBSTANCE, LIQUID, N.O.S.
Hazard class
SARA 311/312 Hazard Categories
9
Acute Health Hazard no
Hazard class 9
Chronic Health Hazard no
Description
Fire Hazard no
Packing Group
Sudden Release of Pressure Hazard no
III
Reactive Hazard no
Packing Group
Description UN3082, Environmentally hazardous substance, liquid, n.o.s (Quaternary ammoniumcompounds, bis(hydrogenated tallow alkyl)dimethyl, chlorides, Mentha Arvensis Oil), 9, III,
CERCLAThis material, as supplied, contains one or more substances regulated as a hazardous substance under the ComprehensiveEnvironmental Response Compensation and Liability Act (CERCLA) (40 CFR 302):
III
Chemical Name Hazardous Substances RQs Extremely HazardousSubstances RQs
RQ
Edetic acid 5000 lb - RQ 5000 lb final RQ RQ 2270kg final RQ
IMDG/IMO
Food and Drug Administration (FDA)The product described in this Material Safety Data Sheet is regulated under the Federal Food, Drug, and Cosmetics Act and is safeto use as per directions on container, box or accompanying literature (where applicable).
ERG Code 9L
UN/ID No
Clean Air Act, Section 112 Hazardous Air Pollutants (HAPs) (see 40 CFR 61)This product does not contain any substances regulated as hazardous air pollutants (HAPS) under Section 112 of the Clean Air ActAmendments of 1990.
UN3082
UN/ID No UN3082
_____________________________________________________________________________________________
Proper shipping name ENVIRONMENTALLY HAZARDOUS SUBSTANCE, LIQUID, N.O.S.
Page 7 / 9
Description
Hazard class 9
_____________________________________________________________________________________________Revision Date: 06-Jun-201292245784 - Nioxin Scalp Therapy 4
CWA - Toxic Pollutants
TSCA Exempt
Edetic acid
DSL Exempt
X
CWA - Priority Pollutants
NDSL Exempt
CWA - HazardousSubstances
Perfumes contained with the products comply with appropriate IFRA guidance.
California Proposition 65This product is not subject to warning labeling under California Proposition 65
Legend TSCA - United States Toxic Substances Control Act Section 8(b) Inventory
International Regulations
DSL/NDSL - Canadian Domestic Substances List/Non-Domestic Substances List
Edetic acid 5000 lb
U.S. State Regulations
Canada
- -
WHMIS Hazard ClassNot subject to WHMIS classification
X
Clean Water ActThis product contains the following substances which are regulated pollutants pursuant to the Clean Water Act (40 CFR 122.21and 40 CFR 122.42):
This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations (CPR) and theMSDS contains all the information required by the CPR. This product is regulated by the Food and Drug Administration of HealthCanada and is therefore exempt from the requirements of CEPA.
Chemical Name
U.S. State Regulations
International Inventories
CWA - ReportableQuantities
Chemical Name Pennsylvania
06-Jun-2012
16. OTHER INFORMATION
Issuing Date:
_____________________________________________________________________________________________
DisclaimerThe information provided in this Safety Data Sheet is correct to the best of our knowledge, information and belief at the date of itspublication. The information given is designed only as a guidance for safe handling, use, processing, storage, transportation,disposal and release and is not to be considered a warranty or quality specification. The information relates only to the specificmaterial designated and may not be valid for such material used in combination with any other materials or in any process, unlessspecified in the text
06-Jun-2012
Page 8 / 9
Revision Date:
End of MSDS
Material Safety Data Sheet
Issuing Date: 27-May-2014 Revision Date: 27-May-2014 Version 1
1. PRODUCT AND COMPANY INFORMATION
Product ID: 98740661_NA
Product Name NIOXIN Scalp Optimizing Cleanser
Product Type Finished Product - Consumer (Retail) and Professional Use
Recommended Use Personal Beauty Care Product
Synonyms No information available
Manufacturer The Procter & Gamble CompanySharon Woods Innovation Center11510 Reed HartmanHighwayCincinnati OH 45241
E-mail Address pgsds.im@pg.com
Emergency Telephone Transportation (24 HR)CHEMTREC - 1-800-424-9300(U.S./ Canada) or 1-703-527-3887Mexico toll free in country: 800-681-9531
2. HAZARDS IDENTIFICATIONEmergency Overview Irritating to eyes
OSHA regulatory status Consumer Products as defined by the U.S. Consumer Product Safety Act which are usedas intended (typical consumer duration and frequency) are exempt from the OSHA HazardCommunication Standard. When used in a professional setting (at a much higher frequencyand duration than a typical consumer) this material would be considered hazardous by theOSHA Hazard Communication Standard (29 CFR 1910.1200).
WHMIS Not subject to WHMIS classification.
_____________________________________________________________________________________________
Principle routes of exposure Eye contact.
General hazards
Page 1 / 9
This is a personal care or cosmetic product that is safe for consumers and other usersunder normal and reasonably foreseeable use.
_____________________________________________________________________________________________98740661_NA - NIOXIN Scalp Optimizing Cleanser Revision Date: 27-May-2014
4. FIRST AID MEASURES
General advice No hazards which require special first aid measures. When symptoms persist or in all casesof doubt seek medical advice.
Eye contact Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes.Remove contact lenses, if present, after the first 5 minutes, then continue rinsing. Ifsymptoms persist, call a physician.
Skin contact If skin problems occur, discontinue use. If symptoms persist, call a physician.
Ingestion Clean mouth with water and afterwards drink plenty of water. Do NOT induce vomiting. Ifsymptoms persist, call a physician.
Inhalation Move to fresh air.
Protection of first-aiders Use personal protective equipment.
Most important symptoms/effects,acute and delayed
None known.
Notes to Physician Treat symptomatically.
5. FIRE-FIGHTING MEASURES
Flash point Not Applicable
Suitable extinguishing media Dry chemical, CO 2, water spray or alcohol-resistant foam.
Extinguishing media which shall notbe used for safety reasons
No information available.
Special hazard None known based on information supplied.
Special protective equipment forfire-fighters
As in any fire, wear self-contained breathing apparatus pressure-demand, MSHA/NIOSH(approved or equivalent) and full protective gear.
6. ACCIDENTAL RELEASE MEASURES
Personal precautions Avoid contact with the skin and the eyes.
Advice for emergency responders Use personal protective equipment.
Environmental precautions Household: Do not discharge product into natural waters without pre-treatment oradequate dilution. Non-household: Should not be released into the environment.
3. COMPOSITION/INFORMATION ON INGREDIENTS
Hazardous ingredients
Chemical Name CAS-No Weight %Poly(oxy-1,2-ethanediyl),
alpha-sulfo-omega-(dodecyloxy)-, sodium salt (1:1)9004-82-4 5 - 10
Sulfuric acid monododecyl ester sodium salt (1:1) 151-21-3 3 - 7Amides, coco, N-hydroxyethyl 68140-00-1
_____________________________________________________________________________________________
1 - 5Zinc,
bis[1-(hydroxy-kappaO)-2(1H)-pyridinethionato-kappaS2]-, (T-4)-
13463-41-7 1 - 5
Page 2 / 9
_____________________________________________________________________________________________98740661_NA - NIOXIN Scalp Optimizing Cleanser Revision Date: 27-May-2014
Methods for containment Non-household: Prevent further leakage or spillage if safe to do so. Prevent product fromentering drains.
Methods for cleaning up Non-household: Contain spillage, and then collect with non-combustible absorbentmaterial, (e.g. sand, earth, diatomaceous earth, vermiculite) and place in container fordisposal according to local / national regulations (see section 13).
7. HANDLING AND STORAGE
Advice on safe handling Keep out of the reach of children. Observe label precautions.
Technical measures/Storageconditions
Keep out of the reach of children. Keep containers tightly closed in a dry, cool andwell-ventilated place.
8. EXPOSURE CONTROLS/PERSONAL PROTECTION
Exposure Guidelines
Chemical Name CAS-No ACGIH TLV OSHA PEL Mexico PELZinc oxide 1314-13-2 STEL: 10 mg/m3 respirable
fractionTWA: 2 mg/m3 respirable
fraction
TWA: 5 mg/m3 fumeTWA: 15 mg/m3 total dustTWA: 5 mg/m3 respirable
fraction(vacated) TWA: 5 mg/m3
fume(vacated) TWA: 10 mg/m3
total dust(vacated) TWA: 5 mg/m3
respirable fraction(vacated) STEL: 10 mg/m3
fume
Mexico: TWA 5 mg/m3
Mexico: TWA 10 mg/m3
Mexico: STEL 10 mg/m3
Chemical Name CAS-No Alberta Quebec Ontario TWAEV British ColumbiaZinc oxide 1314-13-2 TWA: 2 mg/m3
STEL: 10 mg/m3
TWA: 10 mg/m3
TWA: 5 mg/m3
STEL: 10 mg/m3
TWA: 2 mg/m3
STEL: 10 mg/m3
TWA: 2 mg/m3
STEL: 10 mg/m3
Legend: TLV - Threshold Limit ValueTWAEV - Time Weighted Average Exposure ValueACGIH: (American Conference of Governmental Industrial Hygienists)OSHA: (Occupational Safety & Health Administration)PEL - Permissible Exposure Limit
Engineering Measures Not applicable.
Personal Protective Equipment
Eye Protection If splashes are likely to occur, wear:. Safety glasses with side-shields.
Hand Protection No special protective equipment required.
Skin and Body Protection No special protective equipment required.
Respiratory Protection No special protective equipment required.
Thermal hazards
_____________________________________________________________________________________________
Not applicable.
Hygiene measures Handle in accordance with good industrial hygiene and safety practice. Use personalprotective equipment as required.
Page 3 / 9
Environmental exposure controls See section 6 for more information.
_____________________________________________________________________________________________98740661_NA - NIOXIN Scalp Optimizing Cleanser Revision Date: 27-May-2014
9. PHYSICAL AND CHEMICAL PROPERTIES
Physical State @20°C liquidAppearance white. opaque. viscous liquid.Odor Mint-like
Chemical Name Partition Coefficient (n-octanol/water)Sulfuric acid monododecyl ester sodium salt (1:1) < -2.03Zinc, bis[1-(hydroxy-kappaO)-2(1H)-pyridinethionato-kappaS2]-,(T-4)-
0.9
VOC Content (%) Products comply with US state and federal regulations for VOC content in consumerproducts.
Oxidizing properties No information available
10. STABILITY AND REACTIVITY
Reactivity None under normal use conditions.
Stability Stable under normal conditions.
Hazardous polymerization Hazardous polymerization does not occur.
Hazardous Reactions None under normal processing.
Conditions to Avoid None under normal processing.
Materials to avoid None in particular.
Hazardous Decomposition Products None under normal use.
Property Values Note pH value 6.5 - 8.3Melting/freezing point No information availableBoiling point/boiling range No information availableFlash point Not ApplicableEvaporation rate No information availableflammability (solid, gas) No information availableFlammability Limits in AirUpper flammability limit No information availableLower Flammability Limit No information available
Vapor pressure No information availableVapor density No information availableRelative density No information availableWater solubility No information availableSolubility in other solvents No information availablePartition coefficient: n-octanol/waterNo information availableAutoignition temperature No information available .Decomposition temperature No information available
_____________________________________________________________________________________________
.Viscosity of Product No information available
Page 4 / 9
Bulk Density No information available
_____________________________________________________________________________________________98740661_NA - NIOXIN Scalp Optimizing Cleanser Revision Date: 27-May-2014
11. TOXICOLOGICAL INFORMATION
Product Information
Acute toxicity Irritating to eyes.
Principle routes of exposure Eye contact.
Inhalation No known effect based on information supplied.Skin contact No known effect based on information supplied.Ingestion No known effect based on information supplied.Eye contact Irritating to eyes.
Chemical Name CAS-No LD50 Oral LD50 Dermal LC50 InhalationSulfuric acid monododecyl ester
sodium salt (1:1)151-21-3 977 mg/kg bw (OECD
401; rat)> 500 mg/kg bw (Read
across dataC10-16ASO4, NH4;guideline: Standard
Procedure #10; fixeddose procedure; rabbit;
based on activeingredient)
-
Zinc,bis[1-(hydroxy-kappaO)-2(1H)-pyridine
thionato-kappaS2]-, (T-4)-
13463-41-7 269 mg/kg bw (OECD401, rat)
> 2000 mg/kg bw (EPAOPP 81-2, rat)
1.03 mg/L air (OECD403, rat)
Zinc oxide 1314-13-2 > 5000 mg/kg bw (Similarto OECD 401; standard
acute method; rat)
> 2000 mg/kg bw (OECD402; standard acute
method; rat)
> 5.7 mg/L air (Similar toOECD 403; standard
acute method; rat; 4 h)Chronic Toxicity
Corrosivity No known effect.Sensitization No known effect.Neurological Effects No known effect.Reproductive toxicity The product contains no substances known to be hazardous to health in concentrations
which need to be taken into account.Germ cell mutagenicity There are no known mutagenic chemicals in this product.
_____________________________________________________________________________________________
Developmental toxicity No known effect.Teratogenicity
Page 5 / 9
No known effect.Carcinogenicity Contains no ingredients above reportable quantities listed as a carcinogen.
_____________________________________________________________________________________________98740661_NA - NIOXIN Scalp Optimizing Cleanser Revision Date: 27-May-2014
12. ECOLOGICAL INFORMATION
Ecotoxicity
Chemical Name CAS-No Toxicity to algae Toxicity to fish Toxicity toMicroorganisms
Toxicity todaphnia andother aquaticinvertebrates
Toxicity to otherorganisms
Sulfuric acid monododecylester sodium salt (1:1)
151-21-3 > 120 mg/L(Guideline: DIN38412, part 9;Desmodesmus
subspicatus;static; freshwater;based on growth
rate)
29 mg/L (Similarto OECD 203;Pimephalespromelas;
flow-through;freshwater; based
on activeingredient)
EC50: 135 mg/L(Guideline not
indicated;activated sludge;static; freshwater;respiration rate)
LC50: 5.55 mg/L(Guideline not
indicated;Ceriodaphnia
dubia;flow-through;
freshwater; basedon active
ingredient)
-
Zinc,bis[1-(hydroxy-kappaO)-2(1H)-pyridinethionato-kappaS2]-,(T-4)-
13463-41-7 0.0013 mg/L(Guideline EPA
OPP 122-2, static,Skeletonema
costatum)
0.0026 mg/L (EPAOPP 72-1,
flow-through,Pimephalespromelas)
2.4 mg/L (OECD209, static,
activated sludge)
0.0082 mg/L (EPAOPP 72-2,
flow-through,Daphnia magna)
-
Zinc oxide 1314-13-2 IC50: 0.136 mg/L(OECD 201;
Pseudokirchneriella subcapitata;
static; freshwater;growth rate)
0.112 mg/L (Readacross data onZinc chloride;
ASTM, E-729-88;Thymallus
arcticus; static;freshwater)
EC50: > 1000mg/L (OECD 209;activated sludge
of a predominantlydomestic sewage;static; freshwater;respiration rate)
0.155 mg/L (Readacross data onZinc; US EPA821-R-02-012;Ceriodaphniadubia; static;freshwater)
EC10: 350 mg/kgsoil dw (Readacross data onzinc dichloride;ISO 11268-2;Eisenia fetida;
annelids; naturalsoil)
Chemical Name CAS-No Toxicity to algae Toxicity to fish Toxicity toMicroorganisms
Toxicity todaphnia andother aquaticinvertebrates
Toxicity to otherorganisms
Sulfuric acid monododecylester sodium salt (1:1)
151-21-3 30 mg/L(Guideline: DIN38412, part 9;Desmodesmus
subspicatus;static; freshwater;based on growth
rate)
> 1.357 mg/L(Guideline not
indicated;Pimephalespromelas;
flow-through;freshwater; 42 d)
0.88 mg/L (Similarto
EPA-600/489/001and USEPA
OPPTS 850.1300;Ceriodaphnia
dubia;flow-through;
freshwater; 7 d)Zinc,bis[1-(hydroxy-kappaO)-2(1H)-pyridinethionato-kappaS2]-,(T-4)-
13463-41-7 NOEC: 0.46 µg/L(0.00046 mg/L)
NOEC: 1.22 µg/L(0.00122 mg/L)
0.1 mg/L (OECD209, static,
activated sludge)
NOEC: 2.28 µg/L(0.00228 mg/L)
Zinc oxide 1314-13-2 0.024 mg/L(OECD 201;
Pseudokirchneriella subcapitata;
static; freshwater;growth rate)
0.039 mg/L (Readacross data onZinc chloride;OECD 215;
Oncorhynchusmykiss;
flow-through;freshwater)
NOEC: 0.1 mg/L(Guideline: ISO
DIS 9509;activated sludge
of a predominantlydomestic sewage;static; freshwater;
concentrationbased on element;
nitrification rate)
0.0056 mg/L(Read across data
on Zinc sulfate;EPA/600/R-95-136; Holmesimysis
costata;semi-static;saltwater)
0.0228 mg/L(Read across dataon Zinc chloride;
microcosm/mesocosm; flow-through;freshwater; 4 wk)
Persistence and degradability .
Chemical Name Ready Test Results Persistence and degradability
_____________________________________________________________________________________________
Sulfuric acid monododecyl ester sodium salt (1:1) 95 % (OECD 301 B; aerobic; activatedsludge, domestic, non-adapted; CO2evolution; meets 10 d window criteria)
87.3 % (Similar to OECD 314D; aerobic;natural water / sediment; CO2 evolution; 35
d)Zinc,
bis[1-(hydroxy-kappaO)-2(1H)-pyridinethionato-kappaS2]-,(T-4)-
Page 6 / 9
39% (OECD 301 B) t1/2: 17 hours (River water at ambienttemperature)
Bioaccumulative potential .
_____________________________________________________________________________________________98740661_NA - NIOXIN Scalp Optimizing Cleanser Revision Date: 27-May-2014
13. DISPOSAL CONSIDERATIONS
Waste from Residues / UnusedProducts
Household: Do not discharge product into natural waters without pre-treatment oradequate dilution. Non-household: Should not be released into the environment. Disposeof in accordance with local regulations.
Contaminated packaging Dispose of in accordance with local regulations.
California Hazardous Waste Codes(non-household setting)
331
14. TRANSPORT INFORMATION
DOT Not regulated
TDG Not regulated
MEX Not regulated
IATA Not regulated
ICAO Not regulated
IMDG Not regulated
15. REGULATORY INFORMATIONU.S. Federal Regulations
SARA 313Section 313 of Title III of the Superfund Amendments and Reauthorization Act of 1986 (SARA). This product contains a chemicalor chemicals which are subject to the reporting requirements of the Act and Title 40 of the Code of Federal Regulations, Part 372:.
Chemical Name CAS-No Weight % SARA 313 - ThresholdValues %
Carbonic acid, zinc salt (1:1) 3486-35-9 1.54077 1.0Zinc,
bis[1-(hydroxy-kappaO)-2(1H)-pyridinethionato-kappaS2]-, (T-4)-
13463-41-7 1 1.0
SARA 311/312 Hazard CategoriesAcute Health Hazard YesChronic Health Hazard NoFire Hazard NoSudden release of pressure hazard NoReactive Hazard No
Chemical Name Bioconcentration factor (BCF)Zinc, bis[1-(hydroxy-kappaO)-2(1H)-pyridinethionato-kappaS2]-, (T-4)- 11 (OECD 305 E, Crassostrea virginica)
Zinc oxide 60960Mobility .
Chemical Name
_____________________________________________________________________________________________
KOC ValuesSulfuric acid monododecyl ester sodium salt (1:1) 446 (Guideline not indicated; HPLC estimation method; adsorption;
sediment; at 25 C)Zinc, bis[1-(hydroxy-kappaO)-2(1H)-pyridinethionato-kappaS2]-, (T-4)-
Page 7 / 9
Koc (adsorption): 2347 (Soil #1 sandy loam), 783 (Soil #2 loam),10632 (Sediment #1 sandy loam) and 3596 (Sediment #2 silt
loam); Koc (desorption): 3,293 (Soil #1 sandy loam), 873 (Soil #2loam), 21814 (Sediment #1 sandy loam) and 6523 (Sediment #2
silt loam)Other adverse effects No information available.
_____________________________________________________________________________________________98740661_NA - NIOXIN Scalp Optimizing Cleanser Revision Date: 27-May-2014
CERCLAThis material, as supplied, contains one or more substances regulated as a hazardous substance under the ComprehensiveEnvironmental Response Compensation and Liability Act (CERCLA) (40 CFR 302):.
Chemical Name CAS-No Hazardous Substances RQs Extremely HazardousSubstances RQs
Carbonic acid, zinc salt (1:1) 3486-35-9 1000 lb -hydrogen chloride 7647-01-0 5000 lb 5000 lb
Food and Drug Administration (FDA)The product described in this Material Safety Data Sheet is regulated under the Federal Food, Drug, and Cosmetics Act and is safeto use as per directions on container, box or accompanying literature (where applicable).
Clean Air Act, Section 112 Hazardous Air Pollutants (HAPs) (see 40 CFR 61)This product contains the following substance(s) which are either listed as hazardous air pollutants (HAPS) or VOC's per the CleanAir Act:.
Chemical Name CAS-No CAA (Clean Air Act) - 1990 Hazardous AirPollutants
hydrogen chloride 7647-01-0 X
Clean Water ActThis product contains the following substances which are regulated pollutants pursuant to the Clean Water Act (40 CFR 122.21and 40 CFR 122.42):.
Chemical Name CWA - ReportableQuantities
CWA - Toxic Pollutants CWA - Priority Pollutants CWA - HazardousSubstances
Carbonic acid, zinc salt(1:1)
1000 lb X - X
Zinc,bis[1-(hydroxy-kappaO)-2(1H)-pyridinethionato-kap
paS2]-, (T-4)-
- X - -
Zinc oxide - X - -
hydrogen chloride 5000 lb - - X
U.S. State Regulations (RTK).
Chemical Name New JerseyCarbonic acid, zinc salt (1:1) X
Zinc, bis[1-(hydroxy-kappaO)-2(1H)-pyridinethionato-kappaS2]-,(T-4)-
X
Chemical Name MassachusettsCarbonic acid, zinc salt (1:1) X
Chemical Name PennsylvaniaCarbonic acid, zinc salt (1:1) X
Zinc, bis[1-(hydroxy-kappaO)-2(1H)-pyridinethionato-kappaS2]-,(T-4)-
X
Zinc oxide XSulfuric acid sodium salt (1:2) X
hydrogen chloride XGlycerin X
_____________________________________________________________________________________________
Propylene glycol X
Page 8 / 9
Chemical Name Rhode IslandCarbonic acid, zinc salt (1:1) X
_____________________________________________________________________________________________98740661_NA - NIOXIN Scalp Optimizing Cleanser Revision Date: 27-May-2014
California Proposition 65This product is not subject to warning labeling under California Proposition 65.
International Regulations
Canada WHMIS Hazard ClassNot subject to WHMIS classification.
WHMIS StatementThis product has been classified in accordance with the hazard criteria of the Controlled Products Regulations (CPR) and theMSDS contains all the information required by the CPR. This product is regulated by the Food and Drug Administration of HealthCanada and is therefore exempt from the requirements of CEPA.
International Inventories
TSCAProduct is a personal care product and regulated under FDA.
CEPAP&G Canadian Regulatory reviewed finished products to ensure CEPA Compliance.
Perfumes contained with the products comply with appropriate IFRA guidance.
Legend TSCA - United States Toxic Substances Control Act Section 8(b) InventoryCEPA - Canadian Environmental Protection Act
16. OTHER INFORMATION
Issuing Date:
_____________________________________________________________________________________________
27-May-2014Revision Date: 27-May-2014
Page 9 / 9
DisclaimerThe information provided in this Safety Data Sheet is correct to the best of our knowledge, information and belief at the date of itspublication. The information given is designed only as a guidance for safe handling, use, processing, storage, transportation,disposal and release and is not to be considered a warranty or quality specification. The information relates only to the specificmaterial designated and may not be valid for such material used in combination with any other materials or in any process, unlessspecified in the text
End of MSDS
Material Safety Data Sheet
Issuing Date: 27-May-2014 Revision Date: 27-May-2014 Version 1
1. PRODUCT AND COMPANY INFORMATION
Product ID: 92231187_NA
Product Name NIOXIN Scalp Optimizing Conditioner
Product Type Finished Product - Consumer (Retail) and Professional Use
Recommended Use Personal Beauty Care Product
Synonyms No information available
Manufacturer The Procter & Gamble CompanySharon Woods Innovation Center11510 Reed HartmanHighwayCincinnati OH 45241
E-mail Address pgsds.im@pg.com
Emergency Telephone Transportation (24 HR)CHEMTREC - 1-800-424-9300(U.S./ Canada) or 1-703-527-3887Mexico toll free in country: 800-681-9531
2. HAZARDS IDENTIFICATIONEmergency Overview
OSHA regulatory status Consumer Products as defined by the U.S. Consumer Product Safety Act which are usedas intended (typical consumer duration and frequency) are exempt from the OSHA HazardCommunication Standard. When used in a professional setting (at a much higher frequencyand duration than a typical consumer) this material would NOT be considered hazardous bythe OSHA Hazard Communication Standard (29 CFR 1910.1200).
WHMIS Not subject to WHMIS classification.
_____________________________________________________________________________________________
Principle routes of exposure None reasonably foreseeable.
General hazards
Page 1 / 8
This is a personal care or cosmetic product that is safe for consumers and other usersunder normal and reasonably foreseeable use.
_____________________________________________________________________________________________92231187_NA - NIOXIN Scalp Optimizing Conditioner Revision Date: 27-May-2014
4. FIRST AID MEASURES
General advice No hazards which require special first aid measures. When symptoms persist or in all casesof doubt seek medical advice.
Eye contact Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes.Remove contact lenses, if present, after the first 5 minutes, then continue rinsing. Ifsymptoms persist, call a physician.
Skin contact If skin problems occur, discontinue use. If symptoms persist, call a physician.
Ingestion Clean mouth with water and afterwards drink plenty of water. Do NOT induce vomiting. Ifsymptoms persist, call a physician.
Inhalation Move to fresh air.
Protection of first-aiders Use personal protective equipment.
Most important symptoms/effects,acute and delayed
None known.
Notes to Physician Treat symptomatically.
5. FIRE-FIGHTING MEASURES
Flash point Not Applicable
Suitable extinguishing media Dry chemical, CO 2, water spray or alcohol-resistant foam.
Extinguishing media which shall notbe used for safety reasons
No information available.
Special hazard None known based on information supplied.
Special protective equipment forfire-fighters
As in any fire, wear self-contained breathing apparatus pressure-demand, MSHA/NIOSH(approved or equivalent) and full protective gear.
6. ACCIDENTAL RELEASE MEASURES
Personal precautions None under normal use conditions.
Advice for emergency responders Use personal protective equipment.
Environmental precautions Household: Do not discharge product into natural waters without pre-treatment oradequate dilution. Non-household: Should not be released into the environment.
3. COMPOSITION/INFORMATION ON INGREDIENTS
Hazardous ingredients
Chemical Name CAS-No Weight %1-Octadecanol 112-92-5 1 - 5
Octadecanamide, N-[3-(dimethylamino)propyl]- 7651-02-7
_____________________________________________________________________________________________
1 - 5Zinc,
bis[1-(hydroxy-kappaO)-2(1H)-pyridinethionato-kappaS2]-, (T-4)-
13463-41-7 0.1 - 1
Page 2 / 8
_____________________________________________________________________________________________92231187_NA - NIOXIN Scalp Optimizing Conditioner Revision Date: 27-May-2014
Methods for containment Non-household: Prevent further leakage or spillage if safe to do so. Prevent product fromentering drains.
Methods for cleaning up Non-household: Contain spillage, and then collect with non-combustible absorbentmaterial, (e.g. sand, earth, diatomaceous earth, vermiculite) and place in container fordisposal according to local / national regulations (see section 13).
7. HANDLING AND STORAGE
Advice on safe handling Keep out of the reach of children. Observe label precautions.
Technical measures/Storageconditions
Keep out of the reach of children. Keep containers tightly closed in a dry, cool andwell-ventilated place.
8. EXPOSURE CONTROLS/PERSONAL PROTECTION
Exposure Guidelines This product does not contain any hazardous materials with occupational exposure limitsestablished by the region specific regulatory bodies.
Engineering Measures Not applicable.
Personal Protective Equipment
Eye Protection No special protective equipment required.
Hand Protection No special protective equipment required.
Skin and Body Protection No special protective equipment required.
Respiratory Protection No special protective equipment required.
Thermal hazards
_____________________________________________________________________________________________
Not applicable.
Hygiene measures None under normal use condtions.
Page 3 / 8
Environmental exposure controls See section 6 for more information.
_____________________________________________________________________________________________92231187_NA - NIOXIN Scalp Optimizing Conditioner Revision Date: 27-May-2014
9. PHYSICAL AND CHEMICAL PROPERTIES
Physical State @20°C liquidAppearance white. Off-white.Odor Mint-like
Chemical Name Partition Coefficient (n-octanol/water)1-Octadecanol 7.4 (Guideline: ASTM E 1147, HPLC method)Zinc, bis[1-(hydroxy-kappaO)-2(1H)-pyridinethionato-kappaS2]-,(T-4)-
0.9
VOC Content (%) Products comply with US state and federal regulations for VOC content in consumerproducts.
Oxidizing properties No information available
10. STABILITY AND REACTIVITY
Reactivity None under normal use conditions.
Stability Stable under normal conditions.
Hazardous polymerization Hazardous polymerization does not occur.
Hazardous Reactions None under normal processing.
Conditions to Avoid None under normal processing.
Materials to avoid None in particular.
Hazardous Decomposition Products None under normal use.
Property Values Note pH value 4.0 - 5.5Melting/freezing point No information availableBoiling point/boiling range No information availableFlash point Not ApplicableEvaporation rate No information availableflammability (solid, gas) No information availableFlammability Limits in AirUpper flammability limit No information availableLower Flammability Limit No information available
Vapor pressure No information availableVapor density No information availableRelative density No information availableWater solubility No information availableSolubility in other solvents No information availablePartition coefficient: n-octanol/waterNo information availableAutoignition temperature No information available .Decomposition temperature No information available
_____________________________________________________________________________________________
.Viscosity of Product No information available
Page 4 / 8
Bulk Density No information available
_____________________________________________________________________________________________92231187_NA - NIOXIN Scalp Optimizing Conditioner Revision Date: 27-May-2014
11. TOXICOLOGICAL INFORMATION
Product Information
Acute toxicity Product does not present an acute toxicity hazard based on known or supplied information.
Inhalation No known effect based on information supplied.Skin contact No known effect based on information supplied.Ingestion No known effect based on information supplied.Eye contact No known effect based on information supplied.
Chemical Name CAS-No LD50 Oral LD50 Dermal LC50 Inhalation1-Octadecanol 112-92-5 > 2000 mg/kg bw (OECD
401, rat)> 2,000 mg/kg bw
(Rabbit)-
Octadecanamide,N-[3-(dimethylamino)propyl]-
7651-02-7 Low acute toxicity in ratswith a LD50 values
exceeding 2000 mg/kgbw
Low acute toxicity inrabbits with LD50 valuesexceeding 2000 mg/kgbw (read-across from
related substance)
-
Zinc,bis[1-(hydroxy-kappaO)-2(1H)-pyridine
thionato-kappaS2]-, (T-4)-
13463-41-7 269 mg/kg bw (OECD401, rat)
> 2000 mg/kg bw (EPAOPP 81-2, rat)
1.03 mg/L air (OECD403, rat)
Chronic Toxicity
Corrosivity No known effect.Sensitization No known effect.Neurological Effects No known effect.Reproductive toxicity The product contains no substances known to be hazardous to health in concentrations
which need to be taken into account.Germ cell mutagenicity There are no known mutagenic chemicals in this product.
_____________________________________________________________________________________________
Developmental toxicity No known effect.Teratogenicity
Page 5 / 8
No known effect.Carcinogenicity Contains no ingredients above reportable quantities listed as a carcinogen.
_____________________________________________________________________________________________92231187_NA - NIOXIN Scalp Optimizing Conditioner Revision Date: 27-May-2014
13. DISPOSAL CONSIDERATIONS
12. ECOLOGICAL INFORMATION
Ecotoxicity
Chemical Name CAS-No Toxicity to algae Toxicity to fish Toxicity toMicroorganisms
Toxicity todaphnia andother aquaticinvertebrates
Toxicity to otherorganisms
1-Octadecanol 112-92-5 > 100 mg/L(OECD 201,
Scenedesmussubspicatus )
> 0.4 mg/L (EUMethod C.1,
Salmo gairdneri,semi-static)
EC0: > 10000mg/L
(Pseudomonasputida)
1700 mg/L(Guideline:
German IndustryStandard DIN
38412, Part 11;May 1984,
Daphnia magna,static)
-
Octadecanamide,N-[3-(dimethylamino)propyl]-
7651-02-7 ErC50 (72h) =0.14 mg/L
ErC10 (72h) =0.07 mg/L
LC50 (96h) = >0.1-<1 mg/L
NOEC = 0.1 mg/L
NOEC = 100 mg/L EC50 (48h) = 0.38mg/L
NOEC = 0.2 mg/L
-
Zinc,bis[1-(hydroxy-kappaO)-2(1H)-pyridinethionato-kappaS2]-,(T-4)-
13463-41-7 0.0013 mg/L(Guideline EPA
OPP 122-2, static,Skeletonema
costatum)
0.0026 mg/L (EPAOPP 72-1,
flow-through,Pimephalespromelas)
2.4 mg/L (OECD209, static,
activated sludge)
0.0082 mg/L (EPAOPP 72-2,
flow-through,Daphnia magna)
-
Chemical Name CAS-No Toxicity to algae Toxicity to fish Toxicity toMicroorganisms
Toxicity todaphnia andother aquaticinvertebrates
Toxicity to otherorganisms
Zinc,bis[1-(hydroxy-kappaO)-2(1H)-pyridinethionato-kappaS2]-,(T-4)-
13463-41-7 NOEC: 0.46 µg/L(0.00046 mg/L)
NOEC: 1.22 µg/L(0.00122 mg/L)
0.1 mg/L (OECD209, static,
activated sludge)
NOEC: 2.28 µg/L(0.00228 mg/L)
Persistence and degradability .
Chemical Name Ready Test Results Persistence and degradability1-Octadecanol 67% (activated sludge, readily
biodegradable, but failing 10-day window)Half life: 1.1 day (sediment, primary
degradation, for readily bioavailable testmaterial), 34.7 day (sediment, primary
degradation, less bioavailable test material)Zinc,
bis[1-(hydroxy-kappaO)-2(1H)-pyridinethionato-kappaS2]-,(T-4)-
39% (OECD 301 B) t1/2: 17 hours (River water at ambienttemperature)
Bioaccumulative potential .
Chemical Name Bioconcentration factor (BCF)1-Octadecanol 100000 L/kg (Calculated value)
Zinc, bis[1-(hydroxy-kappaO)-2(1H)-pyridinethionato-kappaS2]-, (T-4)- 11 (OECD 305 E, Crassostrea virginica)Mobility .
Chemical Name KOC Values1-Octadecanol
_____________________________________________________________________________________________
471350 L/Kg (adsorption, batch equilibrium method)Octadecanamide, N-[3-(dimethylamino)propyl]- Koc = ~1,000-500,000
Zinc, bis[1-(hydroxy-kappaO)-2(1H)-pyridinethionato-kappaS2]-, (T-4)-
Page 6 / 8
Koc (adsorption): 2347 (Soil #1 sandy loam), 783 (Soil #2 loam),10632 (Sediment #1 sandy loam) and 3596 (Sediment #2 silt
loam); Koc (desorption): 3,293 (Soil #1 sandy loam), 873 (Soil #2loam), 21814 (Sediment #1 sandy loam) and 6523 (Sediment #2
silt loam)Other adverse effects No information available.
_____________________________________________________________________________________________92231187_NA - NIOXIN Scalp Optimizing Conditioner Revision Date: 27-May-2014
Waste from Residues / UnusedProducts
Household: Do not discharge product into natural waters without pre-treatment oradequate dilution. Non-household: Should not be released into the environment. Disposeof in accordance with local regulations.
Contaminated packaging Dispose of in accordance with local regulations.
California Hazardous Waste Codes(non-household setting)
561
14. TRANSPORT INFORMATION
DOT Not regulated
TDG Not regulated
MEX Not regulated
IATA Not regulated
ICAO Not regulated
IMDG Not regulated
15. REGULATORY INFORMATIONU.S. Federal Regulations
SARA 313Section 313 of Title III of the Superfund Amendments and Reauthorization Act of 1986 (SARA). This product does not contain anychemicals which are subject to the reporting requirements of the Act and Title 40 of the Code of Federal Regulations, Part 372.
SARA 311/312 Hazard CategoriesAcute Health Hazard NoChronic Health Hazard NoFire Hazard NoSudden release of pressure hazard NoReactive Hazard No
CERCLAThis material, as supplied, does not contain any substances regulated as hazardous substances under the ComprehensiveEnvironmental Response Compensation and Liability Act (CERCLA) (40 CFR 302) or the Superfund Amendments andReauthorization Act (SARA) (40 CFR 355). There may be specific reporting requirements at the local, regional, or state levelpertaining to releases of this material.
Food and Drug Administration (FDA)The product described in this Material Safety Data Sheet is regulated under the Federal Food, Drug, and Cosmetics Act and is safeto use as per directions on container, box or accompanying literature (where applicable).
Clean Air Act, Section 112 Hazardous Air Pollutants (HAPs) (see 40 CFR 61)This product contains the following substance(s) which are either listed as hazardous air pollutants (HAPS) or VOC's per the CleanAir Act:.
Chemical Name CAS-No CAA (Clean Air Act) - 1990 Hazardous AirPollutants
2-Phenoxyethanol 122-99-6 X
_____________________________________________________________________________________________
Clean Water ActThis product contains the following substances which are regulated pollutants pursuant to the Clean Water Act (40 CFR 122.21and 40 CFR 122.42):.
Chemical Name
Page 7 / 8
CWA - ReportableQuantities
CWA - Toxic Pollutants CWA - Priority Pollutants CWA - HazardousSubstances
_____________________________________________________________________________________________92231187_NA - NIOXIN Scalp Optimizing Conditioner Revision Date: 27-May-2014
Zinc,bis[1-(hydroxy-kappaO)-2(1H)-pyridinethionato-kap
paS2]-, (T-4)-
- X - -
U.S. State Regulations (RTK).
Chemical Name PennsylvaniaZinc, bis[1-(hydroxy-kappaO)-2(1H)-pyridinethionato-kappaS2]-,
(T-4)-X
2-Phenoxyethanol XBenzyl alcohol X
Propylene glycol X
California Proposition 65This product is not subject to warning labeling under California Proposition 65.
International Regulations
Canada WHMIS Hazard ClassNot subject to WHMIS classification.
WHMIS StatementThis product has been classified in accordance with the hazard criteria of the Controlled Products Regulations (CPR) and theMSDS contains all the information required by the CPR. This product is regulated by the Food and Drug Administration of HealthCanada and is therefore exempt from the requirements of CEPA.
International Inventories
TSCAProduct is a personal care product and regulated under FDA.
CEPAP&G Canadian Regulatory reviewed finished products to ensure CEPA Compliance.
Perfumes contained with the products comply with appropriate IFRA guidance.
Legend TSCA - United States Toxic Substances Control Act Section 8(b) InventoryCEPA - Canadian Environmental Protection Act
16. OTHER INFORMATION
Issuing Date:
_____________________________________________________________________________________________
27-May-2014Revision Date: 27-May-2014
Page 8 / 8
DisclaimerThe information provided in this Safety Data Sheet is correct to the best of our knowledge, information and belief at the date of itspublication. The information given is designed only as a guidance for safe handling, use, processing, storage, transportation,disposal and release and is not to be considered a warranty or quality specification. The information relates only to the specificmaterial designated and may not be valid for such material used in combination with any other materials or in any process, unlessspecified in the text
End of MSDS
top related