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Patient Safety/Ethics

Perioperative Aspects of OSA

Post–Op Opioids

Post Covid Lab Operations

Peter Allen, BSRC, RRT-NPS-SDS, RPSGT

Philadelphia Sleep Conference 2020

1

2

Conflicts of Interest

• Main Line Health System

• NBRC Sleep Exam Consultant

• Member: AAST, AASM, AARC, SASM

• Current Board Member PA Sleep

Society

3

Questions for Attendees

• How many Night Sleep Technologists?

• How many RTs? How many Directors

• How many labs are back to Pre-Covid #s?

• How many are directly involved with a

Perioperative OSA and Opioid

Management Program?

4

Goals

• Brief Overview of Perioperative Aspects

• Discuss Post-Op OSA & Opioids

• Discussion of Attendees Experiences

• Patient/Technologist Safety Post Covid

• Lab Start-up after Covid

• Solutions

• One or Two Ideas Back to Labs

5

Learning Objectives

• Identification of the “At Risk” Patient

• Review of Adverse Outcomes

• Tools

• Why, Who, Where, What, How

• Supporting Perioperative OSA

Management

• Raising Questions for Discussion

6

Why Perioperative Management?

• At Risk OSA Population is Growing

• More OSA Patient Post-Op Complications

• Respiratory Failure

• Re-Intubation

• Unexpected ICU Admissions

• Increased PACU Time

• Increased Suffering/Liability/Cost

7

Raising Questions

• How often do you see respiratory

emergencies in the hospital?

• How many could OSA have been factor?

• Unexpected Deaths in the PACU

• Unexpected Deaths 24 hrs after Surgery

• Within one week of Surgery?

8

Payment for Performance

• Value-Based Purchasing

• Rewards

• Disincentives

• Quality-Payment Alignment

http://www.ahrq.gov/qual/qpayment.htm

• Implementation Timelines

http://healthreform.kff.org/timeline.aspx

9

American Society of Anesthesiologists

• 2006 Commissioned a Task Force that

Identified the Importance of Pre-Screening

surgery patients for the presence of

Obstructive Sleep Apnea (OSA).

• Purpose: Prevent Post-Surgical

Respiratory Events

• Anesthesiology 2006; 104:1081-93

10

2008 National Patient Safety Goals

• Proposed Goal 17 from Task Force

• Reduce Risk of Post-Operative

Complications for Patients with

Obstructive Sleep Apnea

• Organization screens potential OSA

patients prior to surgical procedures

involving centrally acting anesthetic and/or

analgesic agents.

11

Epidemiology of OSA

• It is estimated that 75% to 95% of patients

with OSA are not yet diagnosed.

• Many who are diagnosed are not being

treated effectively.

• Body Mass Index>30

• Estimates are that 26% of Adults are at

Risk

• 80%-Bariatric/60%-Diabetic/40%-CHF

12

Pathophysiology of OSA

• Awake: Airway Patent/Neuromuscular Compensation

• Sleep Onset

• Neuromuscular compensation is lost

• Airway Collapses

• Apnea Occurs

• Hypoxia & Hypercapnia ensue

• Ventilatory effort increases

• Arousal from sleep

• Pharyngeal muscle tone increases

• Patent airway restored

• Hypoxia and Hypercapnia improved by hyperventilation

13

OSA Increasing

• Obesity is increasing at epidemic

proportions which is only adding to the

problem of increasing numbers of “at risk”

patients presenting for surgery.

• Obesity Maps

14

Associated OSA Conditions

• Obesity Hypertension

• Depression Coronary Artery Disease

• Accidents Arrhythmias

• Diabetes Left side heart enlargement

• GERD LV Dysfunction

• Stroke Congestive Heart Failure(CHF)

15

Anesthesia Concerns with OSA

• OSA patients are more susceptible to airway collapse without anesthesia.

• OSA can affect all three phases of perioperative period.

• Anesthesiologists role in identification of the at risk OSA patient.

• Upper airway dilator muscles impaired.

• Effect may last for hours

• Eikermann, et. Al., AmJRespirCritCareMed 2007 175:9-15

16

Anesthesia

• Impairs airway patency

• Increases difficulty of intubation

• Brain response less effective

• Narcotics decrease sensitivity to CO2

• Respiratory drive/rate depressed

17

Anesthesia

• Upper airway muscle tone reduced with

opiates, sedatives and volatile agents.

• Perpheral control of O2 inhibited

• Recovery rooms

• Local and regional nerve block options

• Malampatti Scores 1-4

• Patients now encouraged to bring PAP

18

Anesthesia

• Unexpected Risks during

Administration of Conscious Sedation:

Previously Undiagnosed Obstructive

Sleep Apnea

• Annals of Internal Medicine, 2003;139:

707-708

• Pressman, et. Al.

19

Case Reports 1of 6

• Male 65 years of age-Radical prostatectomy

• History showed Positive OSA Profile

• Not diagnosed/treated

• Morphine 5 mg, epidural

• 8 hours later found unresponsive

• Apneic with Cyanosis

• Patient recovered

20

Case Report 2 of 6

• Male 38 years of age-Emergent mastoidectomy

• History of loud snoring

• Diagnosed with OSA, but never treated

• Upon extubation patient airway collapses

• Reintubated

21

Case Report 3 of 6

• Male 41 years of age-Orthopedic surgery

• Diagnosed, but not treated

• Epidural opiods

• Post-op day 2 found unresponsive

• Irregular respiratory pattern

• Cardiac arrest lead to death

22

Case Report 4 of 6

• Female 42 years of age-Laproscopic surgery

• Diagnosed with OSA, but not treated

• Post-op prolonged heart block during sleep

23

Case Report 5 of 6

• Obese male, 42 years of age-Surgery

• Diagnosed with OSA, not treated

• Morphine

• Cardiac arrest

• Severe hypoxia followed by cerebral silence

24

Case Report 6 of 6

• 101 OSA patients and 101 matched controls

• Hip & knee surgery

• OSA patient diagnosis prior to or after surgery

• Controls did not get PSG-????

• Post-op complications greater in OSA patients

• Hospital reported longer stays for OSA group

• Hospital reported more ICU transfers/OSA pts.

Parker Stewart’s Bill

• Uintah Basin Medical Center

• 3 unexplained deaths post-op

• Parkers death ruled Pneumonia/Ethics

• Post-Op Opioids, common factor

25

At Home Monitoring

• Being studied at this time

• Respiratory Rate

• Pulse Oximetry

• Capnography

• Hospital Revenue???

• Masimo

26

Peer Review Article

• HOME MONITORING OF POST-OPERATIVE EAR, NOSE & THROAT

(ENT) PATIENTS FOR OPIOID INDUCED RESPIRATORY DEPRESSION-

--MORE THAN OSA

• PRESENTING AUTHOR: Kim Bennion MsHS, RRT, CHC, Intermountain

Healthcare

• CO-AUTHOR: Shaylynn Uresk BSRT, RRT, SDS, Uintah Basin Medical

Center

• BACKGROUND: Opioid related deaths have been rapidly increasing1. A

recent study suggested oxygen saturation (SpO2) & other overnight

oximetry measurements may provide additional Opioid Induced Respiratory

Depression (OIRD) risk stratification insight2.

27

Parker References

• CDC’s report on opioid related deaths• https//www.cdc.gov/drugoverdose/epidemic/index.html

• Suen C, Ryan et al

• Sleep study and oximetry parameters for predicting

postoperative complications in patients with OSA.

• Chest ; 155(4):855-867 2019

• https://youtu.be/R-4JwdUC4hO Parker’s Story

28

29

OSA – Diagnosis

• Clinical examination(history and physical

examination) carries a diagnostic sensitivity and

specificity of only 50 to 60% even when

performed by experienced sleep physicians

• Clinics of Chest Med 1998; 19:1-19

• If it walks like, talks like, looks like a ….

• Its OSA

• If it walks like, talks like, looks like a ….

• Its OSA

30

OSA Obvious as a Duck

31

Preoperative screening for OSA

• Stop Bang Questionnaire with H&P

• Preoperative diagnosis

• Referral to sleep disorder center

• Preoperative treatment if possible

• PAP Treatment prior to surgery

• PAP Treatment documented prior to surgery

32

Identifying the Problem

33

Stop-Bang Stop-Bang Stop-Bang

• 1. Do you Snore loudly?

• 2. Do you often feel Tired during the daytime?

• 3. Has anyone Observed you stop breathing during your sleep?

• 4. Do you have or are you being treated for high blood Pressure? Stop

• 5. BMI more than 35 kg/m ?

• 6. Age over 50?

• 7. Neck circumference greater than 40cm?

• 8. Gender male? Bang

• High Risk of OSA=Yes to 3 or more items

• Low Risk of OSA= Yes to less than 3 items

34

American Society of Anesthesiology

Recommendations

• Anesthesiologists are working with Surgeons

• Develop Protocols

• Get suspected OSA patients diagnosed and

treated prior to surgery whenever possible

• If diagnosis of OSA is made on the day of the

surgery, then patient and family needs to be

informed of the potential implications of OSA on

the perioperative course.

35

ASA Recommendations Continued

• Be prepared for difficult intubation

• Choice of anesthetic technique

• Oximetry and end-tidal CO2 monitoring

• Full reversal of neuromuscular blocking agents

• Consider non-supine extubation.

• General anesthesia preferable to deep sedation

• Spinal epidural considerations vs IV

• Use of opioids vs regional anesthesia

• Discharge delay a consideration

36

Perioperative Program Awareness

• Contact these areas all at the same time

• Bio-Ethics Department

• All medical staff members

• Grand Rounds Presentations

• Lunch and Learn AMA CEUs

• Community Outreach Programs

• Allied Healthcare Staff

• Home Care Companies

• Manufacturers

• Implement Outcome Tracking Protocols

Home Monitoring

• Check w Masimo

• DME/Hospital Revenue

• Physician/Patient Education is Key

37

38

Perioperative Management of OSA,

Budget

• Questions to Ask:

• Cost Center vs Revenue Center

• What is it going to cost to implement or

to increase awareness?

• What will it cost if we do not

implement or promote?

39

Hospital Implications

• At risk patients not served-Ethical aspects

• Patient Safety/Patient experience

• Hospital revenue

• Hospital reputation

• Hospital recognition

• Physician revenues/Sleep Lab Revenues

• Surgical Risk Liability and SurgSchedules

40

HME Considerations

• Perioperative program will:

• Drive PAP business higher

• Drive O2 business higher

• Increase your referral base

• Improved relations with area medical and

surgi-centers

41

Sleep Disorder Centers

• Additional Revenue

• Navigators???

• Increase Referral Base

• Reinforces the fact that to survive sleep

disorder centers need to diversify/change

their sales and marketing focus on more

complex patients and new opportunities.

• Periop, Stroke, CHF, Diabetes-In House

42

Working Together

• Primary Care Physicians

• Surgeons

• Anesthesiologists

• Allied Health, Nursing, Respiratory Care

• Sleep Disorder Centers

• Home Care Companies

• Hospital Administration

Post Covid Sleep Lab Thoughts

• Performing HSTs, Performing PSGs/PAP?Note: Market/Referral Sources Lost can stay lost

• Keys to Bringing Back Your Numbers

• Disposable Everything (Even HSTs)

• PPE for Technologists

• Patient Screening at every stage of process

• Room Cleaning Machines

• Negative Air Rooms

43

44

Helpful Organizations

• American Society of Anesthesiology

• ASA

• Society of Anesthesia & Sleep Medicine

• SASM

American College of Chest Physicians

ACCP

American Academy of Sleep Medicine

AASM and AARC

45

Summary

• Patients with OSA

• Make up a significant portion of the surgical population and will only

increase as obesity trends move upward.

• Most are not identified before surgery

• Have an increased risk for perioperative complications

• Can be screened diagnosed and treated to manage perioperatively

to reduce risks.

• Programs can be implemented to identify and treat these patients

without substantial increases in costs, resulting in risk reduction,

improved patient safety and better outcomes.(Needs Champion)

• Implement a Post Covid Lab Program – AASM very helpful.

46

References

• Stop Bang Questionnaire, Anesthesiology, V 108, No 5 May Chung, et al.

• Anesthesiology News Guide to Airway management-Obstructive Sleep Apnea Anesthesia, and Ambulatory Surgery, Bishop, et. al

• Perioperative Screening for and Management of Patients with Obstructive sleep Apnea-Beth Israel Deaconess Medical Center, Boston, MA, Sundar, et. al

• Avoiding adverse outcomes in patients with obstructive sleep apnea(OSA); development and implementation of a perioperative OSA protocol, Bolde, et. al.

• Postoperative Complications in Patients With Obstructive Sleep Apnea, CHEST 2012; 141;436-44, Kaw, et. Al.

• Obstructive Sleep Apnea Syndrome and Perioperative Complications: A Systematic Review of the Literature, Journal of Clinical Medicine, Vol. 8, NO. 2 2012, Vasu, et. Al

• Postoperative Complications in Patients with Obstructive Sleep Apnea Syndrome Undergoing Hip or Knee Replacement: A Case-Control Study 2001 Mayo Foundation, Mayo Clin Proc. 2001;76:897-905 Gupta, et.al.

Home Monitoring of High-Risk

Opioid Patients

• Cheatle MD, Klocek JW and McLessan AT (2012). Managing pain in high-risk patients within a

patient-centered medical home. Translational Behavioral Med. 2012;2(1): 47–56.

• Shoemaker WC, Wo CJ, Bishop MH, Asensio J, Demetriades D, Appel PL, Thangathurai D and

Patil RS (1996). Noninvasive Physiologic Monitoring of High-Risk Surgical Patients. Arch

Surg.1996;131(7):732-737.

• Gwira-Baumblatt JA, Wiedeman C, Dunn JR, Schaffner W, Paulozzi LJ and Jones TF (2014).

High-Risk Use by Patients Prescribed Opioids for Pain and Its Role in Overdose Deaths. JAMA

Intern Med. 2014;174(5):796-801.

• Straus MM, Ghitza UE and Tai B (2013). Preventing deaths from rising opioid overdose in the US

– the promise of naloxone antidote in community-based naloxone take-home programs. Subst

Abuse Rehab. 2013; 4: 65–72.

• Janssens JP, Borel JC, Pepin JL (2011). Nocturnal monitoring of home non-invasive ventilation:

the contribution of simple tools such as pulse oximetry, capnography, built-in ventilator software

and autonomic markers of sleep fragmentation. Thorax 2011; 66 (5): 438-445.

• Sliwinski P, Lagosz M, Gorecka D and Zielinski J (1994). The adequacy of oxygenation in COPD

patients undergoing long-term oxygen therapy assessed by pulse oximetry at home. Euopean

Resp Journal 1994; 7: 274-278.

• 47

• Bohnhorst B, Corina CS and Poets CF (2000). Pulse oximeters’ reliability in detecting hypoxemia

and bradycardia: Comparison between a conventional and two new generation oximeters.

Critical Care Medicine 2000; 28(5):1565–1568.

• Jensen LA, Onyskiw J and Prasad GN (1998). Meta-analysis of arterial oxygen saturation

monitoring by pulse oximetry in adults. Heart & Lung 1998; 27 (6): 387-40.

• Chan ED, Chan MM, Chan MM (2013). Pulse oximetry: Understanding its basic principles

facilitates appreciation of its limitations. Resp. Med. 2013; 107 (6): 789-799.

• Lam T, Nagappa M, WONG J, Singh M, Wong D and Chung F (2017). Continuous Pulse Oximetry

and Capnography Monitoring-Postoperative Respiratory Depression and Adverse Events.

Anesthesia & Analgesia 2017: 125 (6): 2019-2029.

• San Diego Patient Safety Council (2014). Monitoring Patient Outside the ICU Took Kit. Located at

https://www.hqinstitute.org/sites/main/files/file-

attachments/2013_resp_monitoring_patients_tool_kit_june2014_final-appendices_0.pdf.

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Home Monitoring of High-Risk

Opioid Patients

• Kodali BS (2013). Capnography Outside the Operating Rooms. Anesthesiology 2013;118: 192-

201.

• Huttman SE, Windisch W and Storre JH (2014). Techniques for the Measurement and Monitoring

of Carbon Dioxide in the Blood. Annals Am Thoracic Soc 2014; 11 (4): 645-652.

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Home Monitoring of High-Risk

Opioid Patients

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petersleep@comcast.net

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