molecular biology and evolution in genomics era li jun and frederick c.c. leung...
Post on 04-Jan-2016
213 Views
Preview:
TRANSCRIPT
Molecular biology and evolution in genomics era
Li Jun and Frederick C.C. Leung (fcleung@hkucc.hku.hk)5N01, School of Biological Science, The University of Hong Kong
Genotype designation according to phylogenomic tree
Virus evolutionary and epidemiology study
Geographic transmission of virus
Estimation of time of the most recent common ancestor (tMRCA)
Web based tool for PRRSV molecular epidemiology and evolutionary analysis
Genome sequencing and assembly
o Gaps are randomly dispersed in the chromosome. Most of the large gaps reside in RNA gene regions.
o Read coverage along the genome are nearly uniform, with mild random fluctuation.
o Only ~10 potential mis-assembled regions can be detected when sequencing depth is >10x.
RNA seq and differential gene expression analysis
Metagenomics
top related