lipids. lipids lipids are natural products more soluble in nonpolar solvents than in water. some of...
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Lipids
Lipids
Lipids are natural products more soluble in nonpolar solvents than in water.
Some of them are related in that they have acetic acid (acetate) as their biosynthetic origin.
Acetyl coenzyme A serves as the source of acetate.
Some of them are related in that they have isoprene as their biosynthetic origin.
Fats, Oils, and Fatty Acids
Fats and Oils
Fats and oils are naturally occurring mixture of triacylglycerols (also called triglycerides).
Fats are solids; oils are liquids.
RCOCH
CH2OCR'O
CH2OCR"
O
O
O
R'COCH
CH2OCRO
CH2OCR"
O
Fatty Acids
Acids obtained by the hydrolysis of fats and oils are called fatty acids.
Fatty acids usually have an unbranched chain with an even number of carbon atoms.
If double bonds are present, they are almost always cis.
H2OHOCH
CH2OH
CH2OH
O
HOCRO
R'COH
O
HOCR"
Which one of the following is a triacylglycerol (triglyceride), a fat?
A) B)
C) D)
Question
Question
When cetyl palmitate is subjected to saponification conditions (NaOH, H2O, heat) which two compounds will be formed?
A) CH3(CH2)15OH + HOCH2(CH2)14CH3
B) CH3(CH2)14CO2Na + NaO2C(CH2)14CH3
C) CH3(CH2)14CO2H + HOCH2(CH2)14CH3
D) CH3(CH2)15OH + NaO2C(CH2)14CH3
Question
Which of the following is not an expected product of the acid hydrolysis of fats?
A) CH3(CH2)12CO2H
B) HOCH2CH2(OH)CH2OH
C) CH3(CH2)16CO2H
D) CH3(CH2)14CO2H
Fatty Acids
Systematic name: (5Z, 8Z, 11Z, 14Z)-5,8,11,14-Icosatetraenoic acid
Common name: Arachidonic acid
H
H H
H
H HH
H
OH
O
O
HO
OH
COOH
Prostaglandin E2
OH
HO
OH
COOH
Prostaglandin F1
CO2
Hcyclooxygenase
Prostaglandins
aspirin inhibits enzyme
(Chimes?)
Diterpenes & PainAspirin’s Mode of Action - Prostaglandin Cascades
Aspirin Inhibits the Synthesis of Prostaglandins
(prostaglandin endoperoxide synthase)
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