integrating noninvasive blood pressure monitoring with human physiology measurements

Integrating Noninvasive Blood Pressure Monitoring with Human

Physiology Measurements

Experts discuss the fundamentals of real-time, beat-to-beat noninvasive blood pressure (NIBP) monitoring and present new

research capabilities enabled through the integration of NIBP technology and physiological recording systems.

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Walter HabenbacherHead of Sales & Marketing,

CNSystems Medizintechnik AG

NIBP100D-HD Hemodynamic Monitoring @ Your Fingertips

© CNSystems Medizintechnik AG. 2016www.cnsystems.com

www.cnsystems.com

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MOVING FROM SNAPSHOTS… …TO CONTINUOUS INFORMATION

NBP CNAP®

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Hemodynamic monitoring @ your fingertips

NIBP100D-HD – CONTINUOUS & NONINVASIVE

* CE approved / FDA pending.

Blood Pressure

Cardiac Output & Stroke Volume*

Systemic Vascular Resistance*

Pulse Rate

[click to learn more]

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SETUP & CALIBRATION

click to watch the videos[advance to 06:08]

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CNAP® TECHNOLOGY – HOW IT WORKS

IR light picks up blood volume and flow1

2In- and deflating pressure cuff follows pulsation and keeps

blood flow constant 1

3 High accuracy thru calibration with NBP 2

2

IR light

1

Sys

Dia

Mean

3

1 Jan Penaz, Brno, Czech Republic 19732 Fortin J et al.: Continuous noninvasive BP monitoring using concentrically interlocking control loops. Comput in Biol Med 36 (2006)

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CNAP® TECHNOLOGY – HOW IT WORKS

click to watch the video[advance to 10:05]

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SETTING UP MEASUREMENTS IS EASY

Measurement settings

measurement

30min

setup

5min

buffer

5min

Total time: ≈ 40min

Set CNAP Cal Interval to 40min (switch between fingers)

Set NBP Interval to 40min (calibration to upper arm)

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PROVEN TECHNOLOGY OVER DECADES

http://www.cnsystems.com/literature

Task Force® Monitor

NIBP100D

Over 500 peer reviewed publications reflect the trust

in the accuracy and utility in research & clinical settings

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PERFORMANCE DURING VALSALVA

Initial BP rise

Impeded venous return (fall in BP)

Compensation (pulse rate & vasoconstriction)

Pressure release

Overshoot (return of CO)

1

2a

3

4

2b

40

50

60

70

80

90

100

0 10 20 30 40 50 60 70 80

Blo

od P

ressure

[m

mH

g]

VALSALVA1 2a 2b 3 4

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PERFORMANCE DURING VALSALVA

click to watch the video[advance to 14:36]

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THE ROLE OF CARDIAC OUPUT & VASCULAR RESISTANCE

Blood pressure

Resistant

Blood flow

MABP = HR x SV x SVR

The Ohm´s law applied to physiology

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1 Kirby, L. D., & Wright, R. A. (2003). Cardiovascular correlates of challenge and threat appraisals: A critical examination of the Biopsychosocial Analysis. Personality and Social Psychology Bulletin, 7, 216-233.

2 Tomaka, J., Blascovich, J., Kelsey, R. M., & Leitten, C. L. (1993). Subjective, physiological, and behavioral effects of threat and challenge appraisal. Journal of Personality and Social Psychology, 65, 248-260.

3 Lackner, H. K., Weiss, E. M., Schulter, G., Hinghofer-Szalkay, H., Samson, A. C., & Papousek, I. (2013). I got it! Transient Cardiovascular Response to the Perception of Humor. Biological Psychology, 93, 33–40.

BLOOD PRESSURE, CARDIAC OUTPUT AND VASCULAR RESISTANCE

ARE IMPORTANT CV CORRELATES OF CHALLENGE & THREAT

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HEMODYNAMIC MONITORING @ YOUR FINGERTIPS:

CONTINUOUS & NONINVASIVE

Calibrated blood pressure &

hemodynamics

Up & running in 1.5 minutes

Quick set up of measurement

Reliable short and longterm

monitoring

Easy integration

(MP150 / 160)

Frazer Findlay CEO, BIOPAC Systems, Inc.

Integrating NIBP with Human Physiology Measurements

BIOPAC—Inspiring people and enabling discovery about life© BIOPAC Systems, Inc. 2016

www.biopac.com

BIOPAC—Inspiring people and enabling discovery about life

© BIOPAC Systems, Inc. 2016www.biopac.com

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Over 97% of top universities run BIOPAC Systems

THE WORLD DISCOVERSWITH BIOPACSolutions for life science research and education

BIOPAC—Inspiring people and enabling discovery about life

© BIOPAC Systems, Inc. 2016www.biopac.com

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Combining Noninvasive Blood Pressure with other Physiological Signals

BioNomadix

Wireless Physiological

Data

Mobita System

32-Channel EEG / Biopotentials

B-Alert System

9-Channels of EEG and Cognitive States Metrics

MP36R System

4-Universal Channels

MP160 System

16-Channels of Tethered or

Wireless Signals

BIOPAC—Inspiring people and enabling discovery about life

© BIOPAC Systems, Inc. 2016www.biopac.com

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Stimulus Presentation with Triggers for Synchronization

SuperLab® - E-Prime®Presentation®

Virtual Reality

BIOPAC VR Solutions offer real-time feedback

loops and event marking

BIOPAC—Inspiring people and enabling discovery about life

© BIOPAC Systems, Inc. 2016www.biopac.com

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Stationary Eye Tracking

with Visual StimulationUnrestrained Mobile

Eye Tracking

BIOPAC—Inspiring people and enabling discovery about life

© BIOPAC Systems, Inc. 2016www.biopac.com

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BIOPAC—Inspiring people and enabling discovery about life

© BIOPAC Systems, Inc. 2016www.biopac.com

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Hardware CommunicationNIBP100D

Continuous Noninvasive Blood Pressure System

DA100C with TCI105

MP160 System

16-Channel Data Acquisition

System

BIOPAC—Inspiring people and enabling discovery about life

© BIOPAC Systems, Inc. 2016www.biopac.com

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Hardware Communication

CBLNIBP100D-HDHLT100C and 4 x INISO Isolation

Adapters

NIBP100D-HDContinuous Noninvasive

Blood Pressure System with Hemodynamics

Hemodynamic MeasurementCardiac Output (CO), Stroke Volume (SV), Pulse Pressure Variation (PPV), Stroke Volume Variation (SVV), Systemic Vascular

Resistance (SVR)

MP160 System

16-Channel Data Acquisition

System

BIOPAC—Inspiring people and enabling discovery about life

© BIOPAC Systems, Inc. 2016www.biopac.com

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Hardware Communication with Visual StimulusStimulus is delivered to subject at a stationary monitor or by VR...

SuperLabE-PrimeVizardPresentation

Front

FrontBack

STP100C

BIOPAC—Inspiring people and enabling discovery about life

© BIOPAC Systems, Inc. 2016www.biopac.com

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Hardware Communication with Visual StimulusStimulus is delivered to subject at a stationary monitor or by VR...

Front

FrontBack

STP100C

BIOPAC—Inspiring people and enabling discovery about life

© BIOPAC Systems, Inc. 2016www.biopac.com

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Hardware Communication with Visual StimulusStimulus is delivered to subject at a stationary monitor or by VR...

Triggers sent to the MP160 System

Front

FrontBack

STP100C

BIOPAC—Inspiring people and enabling discovery about life

© BIOPAC Systems, Inc. 2016www.biopac.com

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AcqKnowledge Automated Analysis Software

• Arterial Blood Pressure Analysis

• Estimate Cardiac Output from Arterial Blood Pressure

• Baroreflex Sequence Analysis

• Baroreflex Slope Analysis

Demonstration of AcqKnowledge Software[click to watch the demonstration – advance to 31:11]

BIOPAC—Inspiring people and enabling discovery about life

© BIOPAC Systems, Inc. 2016www.biopac.com

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• Combine Noninvasive Blood Pressure with a wide variety of signals

• Interface with stimulus presentation systems such as E-Prime, SuperLab, Presentation and BIOPAC Virtual Reality systems

• Monitor subject eye position, gaze path and facial expressions

• Maintain synchronization across devices

Summary

Walter Habenbacher

office@cnsystems.com

Frazer Findlay

info@biopac.com

For additional information on the products and applications presented during this webinar please visit www.cnsystems.com and www.biopac.com

Thank You