from yu et al.’s website: /oci-info an experimental model for in vivo tumors

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From Yu From Yu et al.et al.’s website: ’s website: www.vet.purdue.edu/cristalwww.vet.purdue.edu/cristal

/oci-info/oci-info

An experimental An experimental model for model for in vivoin vivo

tumorstumors

From Yu From Yu et al.et al.’s website: ’s website: www.vet.purdue.edu/cristalwww.vet.purdue.edu/cristal

/oci-info/oci-info VV

VV

NN

From Yu From Yu et al.et al.’s website: ’s website: www.vet.purdue.edu/cristal/oci-www.vet.purdue.edu/cristal/oci-

infoinfo

Nutrient distributionNutrient distribution

Inverse of OInverse of O22 distribution distribution

From Walerta From Walerta et al.et al. (2000) J. Histochem. (2000) J. Histochem. Cytochem. 48:509-522.Cytochem. 48:509-522.

Published by AAAS

J. Holash et al., Science 284, 1994 -1998 (1999)

Angiogenesis in Implanted Rat C6 GliomasAngiogenesis in Implanted Rat C6 Gliomas

Published by AAAS

J. Holash et al., Science 284, 1994 -1998 (1999)

Cells Sense Hypoxia, Respond by Secreting VEGF and ang-2Cells Sense Hypoxia, Respond by Secreting VEGF and ang-2

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