fine chemicals and fluoronated specialty chemicals

AGC Chemicals Americas, Inc.Your Global Source for Fine Chemicals

–

Global Operations

World’s #1 glass manufacturer

Approximately 51,500 employees

US $13 billion net sales (2013)

200 consolidated subsidiaries in 30 countries

50%Glass

25%Electronics

25%Chemicals/

Other

Global Sales 2013#1 global

supplier of flat and auto glass

Largest global glass supplier to:

NISSANHONDATOYOTA

World’s #1 supplier of ETFE

Global Product Reach

Global Product Reach

Chemicals Products and Other

• Caustic soda – soaps

• Sodium bicarbonate – household detergents

• Sodium hypochlorite – fungicides, bleach

• Urethanes – automobile seats

• Fluorinated resin films – solar cells/architectural/agricultural

• Fluorinated resins/elastomers – coatings/additives/auto/electronics

• Fluorinated water/oil repellents – textile/non-woven/paper

• Fluorinated intermediates – pharmaceuticals/agrochemicals

• Fluorinated solvents – precision cleaning

• Reinforced fluorinated compounds – auto/electronics/other apps

• Silica gel – personal care products/ chromatography/catalysts support

Global Operation of Fine Chemicals Business

HeadquartersTokyo

Sales and Marketing in EuropeAmsterdam

Sales and Marketing in USAExton, PA

All Manufacturing Plants are in Japan

cGMP sites (API) EPA approved (AI) R&D labs Pilot plant Commercial factory

Factory for Fine Chemicals – Chiba Factory

CMP (cGMP ） Plant

LocationChiba, Japan

Operation StartedJanuary 2003 (Production & Analysis Site)

Purpose cGMP multipurpose for

pharma API & intermediates

CMP Major Equipment

Main Points Ultra-Low temperature reaction （ -100 degrees C ） 2 line of GL, SUS and HC

Capacity Number Material Temperature(degrees)

Reactors

1000~6000L 2 GL -30~180

1000~3000L 7 SUS -100~270

100~1000L 2 HC -100~270

Distillation tower 2500L - SUS -

Centrifuges Φ48 - -

Dryers 1000~1200L - -

Filter Dryers 2000L - SUS -

CMP Major Equipment

Factory for Fine chemicals – Chiba Factory

FMP (Fluoro Multi Purpose ） Plant

Operation Started

FMP1 ： 1984 FMP2 ： 2000

Purpose Multi-purpose plant

High pressure gas & dangerous goods

Scale-up from lab to production scale

Handling special fluorine raw materials (TFE etc.)

Factory for Fine Chemicals – Chiba Factory

Capacity Number Material Temperature(degrees)

Reactors

150~480L 2 GL -30~180

60~2400L 7 SUS ~400

550~2400L 3 HC -10~270

8.8L 1 Inconel 500

- Inconel 350

Distillation tower 150~2400L - SUS -

Inspection Record in Chiba Factory

Plant A Plant B

Year License of ManufacturingClassification:Biological product

License of ManufacturingClassification:General API

Pre-approval Inspection

General API

2007 Pre-approval 　Inspection/PMDA

2008 3

2009 GMP Inspection/PMDA

3

GMP Inspection for 　renewal/Chiba Local

Government3

2010 2 3 GMP certification for export/Chiba Local Government

Pre-approval Inspection/TGA

2011 2 4 Pre-approvalInspection/FDA

2012 2 1 GMP Inspection/PMDA(Document Inspection ）

Audit Record in Chiba Factory

Number of Visitors Purpose

Year Japan Overseas QA EMS / BCP Tour

2007 7 2 5

2008 4 1 3

2009 4 2 2

2010 4 5 6 1 2

2011 3 2 4 1

2012 5 1 5 1

Factory for Fine Chemicals – AGC Seimi Chemical

LocationChigasaki-shi Kanagawa-ken, Japan

EstablishedDecember 18, 1947

StockholderAsahi Glass Co.,Ltd.

Purpose Selective fluorination by electrolytic reaction Raw materials and intermediates by GMP

Ultra low temperature reaction

(-80 degrees C)

Lab to Production scale (MT)

Factory for Fine Chemicals – AGC Seimi Chemical

Capacity Number Material Temperature(degrees)

Reactors

100~3000L 12 GL -

100~1000L 11 SUS -50~180

200~500L 4 HC -80~200

160~1500L 2 ETFE -30~120

Distillation tower 300~1500L - - -

Centrifuges Φ20~36

Dryers 500~800L

Factory for Fine Chemicals – AGC Seimi Chemical

Obama Factory

LocationObama Fukui, Japan

EstablishedApril 1998

Factory for Fine Chemicals – AGC Wakasa Chemical

Factory for Fine Chemicals – AGC Wakasa Chemical

Capacity Number Material Temperature(degrees)

Reactors

100~5000L 23 GL -30~150

100~6000L 16 SUS -50~210

300L 1 HC -50~150

Distillation tower 75~1000L - - -

Centrifuges Φ20~48B

Dryers 200~4000L

Filter Dryers 300~1700L

Kaminaka Factory

LocationKaminaka MikataFukui, Japan

Site area28,400m2

EstablishedDecember 2012

Purpose Multi purpose plant for intermediates and ingredients for

agrochemicals Capacity up to 3,000MT per year

Factory for Fine Chemicals – AGC Wakasa Chemical

Kaminaka Plant Pictures

Factory for Fine Chemicals – AGC Wakasa Chemical

Capacity Numbers Material Temperature(degrees C)

Reactors

3000~8000L 12 GL -30~150

5000~10000L 11 SUS -50~150

7000L 2 HC -50~150

Centrifuges Φ48B

Dryers 3000~4000L

LocationKashima ComplexIbaraki, Japan

Site area67,000m2

EstablishedNovember, 1968

Purpose Propylene + Chlorine, C-3 Specialty Chemicals Capacity up to 3,000MT per year

Factory for C-3 Products – Kashima Chemical

C3 Compounds (Kashima Chemical)

Location

Yokohama Kanagawa, Japan

Main Functions

Intellectual Property Investigation

Research for new routes / Development

Study of manufacturing optimums

Scale up

Original API Research

Research Center for Fine Chemicals

Building blocks with “F” components Heterocyclic compounds Fluoroalkylation

General organic reaction Friedel-Crafts Grignard Cross coupling Oxidation / Reduction Sulfur chemistry

Ultra-low temperature reaction( ～　 -100 )℃

C3 compounds

Our Technology

Fluorination technology Electrophilic fluorination Nucleophilic fluorination Halogen exchange Diazo-fluorination “PERFECT”process Electrolytic chemical

fluorination

Our Strength

Proven track record

Commercial production

Advanced technology

R&D focused

Serving the following markets:

Agrochemicals

Pharmaceuticals

Co-catalysts

Stop by Booth #1612

Visit Us in Japan!

AGC Chemicals Americas, Inc.

Intelligent resinsCustom compoundsSmart chemistry solutions

Rev 01 2/13