drug discovery ‘15 - elrig · gene transfer technologies, stem cell manipulation and the growing...

DRUG DISCOVERY ‘15

2ND - 3RD SEPTEMBER 2015

TELFORD INTERNATIONALCONFERENCE CENTRE

www.elrig.org #ELRIGDD15

COFFEE BREAK

POSTER TASTERS

SNAPSHOT PRESENTATIONS

LUNCH - EXHIBITION - POSTERS

Thursday September 3rd

Room: Beckbury

TIME SPEAKER TITLESession Chairs

Modelling Cardiovascular Disease with Pluripotent Stem Cells: a High-Content Approach

Accelerating Human iPSC in vitro Disease Modeling by Introducing Targeted Gene Mutations in Isogenic Cell Lines Through the CRISPR/Cas9 Nuclease System

Adoptive T cell Therapy for Cancer

Hematopoietic Stem Cell Based Gene Therapy for the Treatment of Lysosomal Storage Disorders

Gene Therapy for Choroideremia, an Inherited Cause of Blindness

How Stem Cells Signal to Host Immune Cells

Gabor FoldesNational Heart and Lung Institute, Imperial College London

Vania BroccoliItalian Research Council (CNR) and Ospedale San Raffaele

David GilhamInstitute of Cancer Sciences,Manchester University

Alessandra BiffiTIGET, IRCCS San Raffaele Scientific Institute

Alun BarnardOxford University

Keynote Speaker: Stefano Pluchino Wellcome Trust-MRC Stem Cell Institute, University of Cambridge (UK)

CHAIRS: Aniz Girach, NightstaRx. Angela Gritti, San Raffaele Telethon Institute for Gene Therapy (TIGET)

Gene- and cell-based therapies are fast-growing forms of personalized medicine that rely on steady advances in gene transfer technologies, stem cell manipulation and the growing capacity for genetic reprogramming of mammalian cells. They may fulfill the promise of safe and effective therapies for currently untreatable diseases. The session will describe the latest developments and the crucial challenges for this field, touching on basic science, pre-clinical and clinical studies, with an emphasis on gene therapy approaches for blood, ocular and neurodegenerative disorders, and with a special insight in novel approaches aimed to generate transplantable neuronal populations from induced pluripotent stem cells.

CELL AND GENE THERAPY

PLENARY KEYNOTE: ROOM - IRONBRIDGEThe Development of New Therapeutics for respiratory inflammation

Professor Tracy HussellManchester Collaborative Centre forInflammation Research

9:15 - 10:00

9:10 - 9:15

10:30 - 11:00

10:00 - 10:30

11:00 - 11:30

11:30 - 12:00

12:30 - 14:00

12:00 - 12:30

14:00 - 15:00

15:00 - 15:30

15:30 - 16:00

16:30 - 17:00

16:00 - 16:30

Introduction and Welcome

CLOSE OF CONFERENCE - with prize draw