dr. brian payne - infection chain concept
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The Infection Chain™ Concept
Piglet Approach System Approach
Looking for the root of a problem
Chain of the infection in Epidemiology field: Individual (host)approach
13 April 2023
4Image courtesy of: http://www.cetl.org.uk/learning/img1/chain-infection.jpg
The pig production cycle or “chain”
13 April 20235
Production Chain / Infection Chain
13 April 20236
Sow Herd
Nursery
Finishing
GDU
Multiplier
Production Chain "Infection Chain"
Sow Herd
Nursery
Finishing
GDU
Multiplier
Production Chain "Infection Chain"
“Infection Chain” of swine pathogens
13 April 2023
7
SOW TO PIGLET
TRANSMISSION
PIGLET TO PIGLET
TRANSMISSION
EARLY OR LATE COLONIZATION
AGENT’S SPREAD
NURSERY OR FINISHING
GILT DEVELOPMENT
PROCESS
GILT TO SOW OR SOW TO SOW
TRANSMISSION (SOW HERD INFECTION
DYNAMICS)
Production flow / infection / prevention“Chain”
13 April 20238
Sow Herd
Nursery
Finishing
GDU
Multiplier
Production Chain "Infection Chain" "Prevention Chain"
PRRS…the example
13 April 20239
Role of Vaccine – Immunity for Control PRRSv in Growing Pigs
• Vaccine provides protective immunity that can mitigate the consequences of PRRSv infection
• The common benefit of vaccines is to improve herd health, which in turn improves economic return
• Meta-Analysis of 16 Modified Live PRRS Vaccination Challenge Studies; M.Roof et. al., Emerg Swine Dis Symp, 2007
• Growth Performance Improvement and Mortality Reductions Derived from a PRRS Large-Scale Control Project in the U.S.; J. Angulo, et.al., IPVS, 2012
Statement of the Problem:
•PRRS instability in the breeding herd
• Defined as evidence of PRRSv circulation and transmission vertically and/or horizontally
• Can cause reproductive problems w/ biologic & economic impact
• Can lead to weaning of PRRSv positive piglets w/ biologic & economic impact
• PRRSv Control or Elimination; D.Holtkamp, George Young Conf., 2012
• Assessment of economic impact of PRRSv on U.S. pork producers; D. Holtkamp et.al., JSHAP, 2013
Production flow / infection / prevention“Chain”
13 April 202312
Sow Herd
Nursery
Finishing
GDU
Multiplier
Production Chain "Infection Chain" "Prevention Chain"
Chain Thinking
Production Chain
Infection Chain™
Prevention Chain™
13 April 202313
Chain Thinking
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