dog with acute abdominal pain

Dog with Acute Abdominal Pain

Dennis B. DeNicola, DVM, PhD, DACVPChief Veterinary Educator

IDEXX Laboratories

“Cookie”8 years oldIntact FemaleSheltie dog

Presented with clinical history of acute abdominal pain

“Cookie” - 8 Year-old, SheltieWBC = 18.84 K/L HIGH ( 5.50 – 16.90 )LYM = 0.98 K/L ( 0.70 – 4.90 )MONO = 2.90 K/L HIGH ( 0.10 – 1.40 )NEU = 14.67 K/L HIGH ( 2.00 – 12.00 )EOS = 0.25 K/L ( 0.10 – 1.49 )BASO = 0.04 K/L ( 0.00 – 0.10 )%LYM = 5.2 %%MONO = 15.4 %%NEU = 77.8 %%EOS = 1.3 %%BASO = 0.2 %HCT = 49.2 % ( 37.0 – 55.0 )RBC = 7.21 M/L ( 5.50 – 8.50 )HGB = 14.8 g/dL ( 12.0 – 18.0 )RETIC = 22.8 K/L%RETIC = 0.3 %MCV = 68.3 fL ( 60.0 – 72.0 )RDW = 19.9 % HIGH ( 14.7 – 17.9 )MCHC = 30.1 g/dL LOW ( 31.0 – 37.0 )MCH = 20.54 pg ( 19.50 – 24.50 )PLT = 329 K/L ( 175 – 500 )MPV = 16.69 fLPCT = 0.5 %PDW = 19.2 %

“Cookie” - 8 Year-old, SheltieErythronHCT = 49.2 % ( 37.0 – 55.0 )RBC = 7.21 M/L ( 5.50 – 8.50 )HGB = 14.8 g/dL ( 12.0 – 18.0 )RETIC = 22.8 K/L%RETIC = 0.3 %MCV = 68.3 fL ( 60.0 – 72.0 )RDW = 19.9 % HIGH ( 14.7 – 17.9 )MCHC = 30.1 g/dL LOW ( 31.0 – 37.0 )MCH = 20.54 pg (19.50 – 24.50)

“Cookie” - 8 Year-old, SheltieErythronHCT = 49.2 % ( 37.0 – 55.0 )RBC = 7.21 M/L ( 5.50 – 8.50 )HGB = 14.8 g/dL ( 12.0 – 18.0 )RETIC = 22.8 K/L%RETIC = 0.3 %MCV = 68.3 fL ( 60.0 – 72.0 )RDW = 19.9 % HIGH ( 14.7 – 17.9 )MCHC = 30.1 g/dL LOW ( 31.0 – 37.0 )MCH = 20.54 pg (19.50 – 24.50)

“Cookie” - 8 Year-old, SheltieErythronHCT = 49.2 % ( 37.0 – 55.0 )RBC = 7.21 M/L ( 5.50 – 8.50 )HGB = 14.8 g/dL ( 12.0 – 18.0 )RETIC = 22.8 K/L%RETIC = 0.3 %MCV = 68.3 fL ( 60.0 – 72.0 )RDW = 19.9 % HIGH ( 14.7 – 17.9 )MCHC = 30.1 g/dL LOW ( 31.0 – 37.0 )MCH = 20.54 pg (19.50 – 24.50)

Normal red blood cell density Probable insignificant RDW and MCHC changes since

other parameters are not affected

Erythron – Blood Film

Leukon – Blood Film

“Cookie” - 8 Year-old, SheltieLeukonWBC = 18.84 K/L HIGH ( 5.50 – 16.90 )LYM = 0.98 K/L ( 0.70 – 4.90 )MONO = 2.90 K/L HIGH ( 0.10 – 1.40 )NEU = 14.67 K/L HIGH ( 2.00 – 12.00 )EOS = 0.25 K/L ( 0.10 – 1.49 )BASO = 0.04 K/L ( 0.00 – 0.10 )%LYM = 5.2 %%MONO = 15.4 %%NEU = 77.8 %%EOS = 1.3 %%BASO = 0.2 %

“Cookie” - 8 Year-old, SheltieLeukonWBC = 18.84 K/L HIGH ( 5.50 – 16.90 )

“Cookie” - 8 Year-old, SheltieLeukonWBC = 18.84 K/L HIGH ( 5.50 – 16.90 )

Leukocytosis Minimal

“Cookie” - 8 Year-old, SheltieLeukonWBC = 18.84 K/L HIGH ( 5.50 – 16.90 )LYM = 0.98 K/L ( 0.70 – 4.90 )MONO = 2.90 K/L HIGH ( 0.10 – 1.40 )NEU = 14.67 K/L HIGH ( 2.00 – 12.00 )EOS = 0.25 K/L ( 0.10 – 1.49 )BASO = 0.04 K/L ( 0.00 – 0.10 )%LYM = 5.2 %%MONO = 15.4 %%NEU = 77.8 %%EOS = 1.3 %%BASO = 0.2 %

Leukocytosis Minimal

“Cookie” - 8 Year-old, SheltieLeukonWBC = 18.84 K/L HIGH ( 5.50 – 16.90 )LYM = 0.98 K/L ( 0.70 – 4.90 )MONO = 2.90 K/L HIGH ( 0.10 – 1.40 )NEU = 14.67 K/L HIGH ( 2.00 – 12.00 )EOS = 0.25 K/L ( 0.10 – 1.49 )BASO = 0.04 K/L ( 0.00 – 0.10 )%LYM = 5.2 %%MONO = 15.4 %%NEU = 77.8 %%EOS = 1.3 %%BASO = 0.2 %

Leukocytosis Minimal Mild monocytosis and

minimal neutrophilia Low normal lymphocytes

Leukogram InterpretationMinimal leukocytosis

Mild monocytosisEither tissue demand for macrophages of

glucocorticoid influenceMinimal neutrophilia

Either mild inflammation or glucocorticoid influence

Erythron – Blood Film

Erythron – Blood Film

Leukon – Blood Film

Leukon – Blood Film

Leukon – Blood Film

Leukon – Blood Film

Leukon – Blood Film

Leukon – Blood Film

Leukon – Blood Film

Leukogram InterpretationMinimal leukocytosis

Mild monocytosisEither tissue demand for macrophages of

glucocorticoid influenceMinimal neutrophilia

Either mild inflammation or glucocorticoid influenceBlood film complement

Inflammation (left shift and toxicity in neutrophils)Probable tissue demand for macrophages Probable glucocorticoid influence

“Cookie” - 8 Year-old, SheltieWBC = 18.84 K/L HIGH ( 5.50 – 16.90 )LYM = 0.98 K/L ( 0.70 – 4.90 )MONO = 2.90 K/L HIGH ( 0.10 – 1.40 )NEU = 14.67 K/L HIGH ( 2.00 – 12.00 )EOS = 0.25 K/L ( 0.10 – 1.49 )BASO = 0.04 K/L ( 0.00 – 0.10 )%LYM = 5.2 %%MONO = 15.4 %%NEU = 77.8 %%EOS = 1.3 %%BASO = 0.2 %HCT = 49.2 % ( 37.0 – 55.0 )RBC = 7.21 M/L ( 5.50 – 8.50 )HGB = 14.8 g/dL ( 12.0 – 18.0 )RETIC = 22.8 K/L%RETIC = 0.3 %MCV = 68.3 fL ( 60.0 – 72.0 )RDW = 19.9 % HIGH ( 14.7 – 17.9 )MCHC = 30.1 g/dL LOW ( 31.0 – 37.0 )MCH = 20.54 pg ( 19.50 – 24.50 )PLT = 329 K/L ( 175 – 500 )MPV = 16.69 fLPCT = 0.5 %PDW = 19.2 %