containers and closures

Prepared and presented by Ibrahim bin Abdullah for MSU Diploma Pharmacy

BOTTLES AND CONTAINERS

PACKAGING MATERIAL

Glass

Plastic

AdvantagesDisadvantages

AdvantagesDisadvantages

GLASSAdv

• Inert• Impervious• Easy inspection• Easy to clean• Easy to sterilize• Easy to shape

Disadv

• Fragile• Release alkali• Expensive• Heavy

PLASTICAdv

• Flexible• Light• Can be heat-sealed• Easily moulded• 2o packaging• Cheap

Disadv

• Less inert• Cracking, distortion• Less permeable• Heat sensitive• Charged• Easily leached

GLASS

Type 1 Type 2

Type 3 Type 4

Type

Know made, advantages, disadvantages and uses of each type

INJECTION

CONTAINER

INJECTION CONTAINERCharacteristics

Material should not affect the content

Must be strong enough to withstand the changes of

temperature and pressure (heat sterilization)

Protect the contents from harmful light radiations

Must be suitable for repeated use

Easy to clean

Cheap enough to discard

Should be transparent and colourless

INJECTION CONTAINERType

Single-dose injections of small

volume

Multiple-dose

injections

Single-dose injections

of large volume

AmpoulesCartridges

Glass bottlesPVC collapsible bagsSemi-rigid polythene containers

CLOSURES

CLOSURESCharacteristics

Good ageing qualities

Satisfactory hardness and elasticity

Resistance to sterilisation condition

Impermeable (resistant) to moisture and air

Negligible release of undesirable substances

Negligible extraction of injection ingredients

QUESTION TIME

Ask questions through email. Send your questions to:

ibrahim@msu.edu.my