connective tissue proper cartilage bone
Post on 04-Jan-2016
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Connective Tissue Proper
Cartilage
Bone
Connective Tissue Proper:
Loose Connective Tissue
Dense Connective Tissue
Adipose Tissue
Loose Connective Tissue:
Locations:-Space between skin and internal body parts-adventitia of blood vessels-surrounds gland parenchyma (epi)-lamina propria of GI tract
Loose Connective Tissue contains:
-ground substance-fibroblasts-adipose cells-macrophages-mast cells-undifferentiated cells-collagen, elastic and reticular fibers
Dense Connective Tissue:
Dense Irregular CT
Dense Regular CT
Dense Regular Collagenous CT
Dense Regular Elastic CT
Reticular Tissue
Adipose Tissue
Dense Connective Tissue:
-same components as LCT -fewer cells, more fibers
Dense Irregular CT - fiber arrangement is irregular-dermis of skin, nerve sheaths, capsules of spleen, -Testes, kindney, lymph nodes
Dense Regular Collagenous CT
– coarsely packed collagen bundles densely packed- parrallel or sheet like orientation- little space for cells and ground substance- Thin, sheet-like fibroblasts between collagen
bundles- Tendons and ligaments
Dense regular elastic connective tissue
• Around large blood vessels
• In the vertebral column
• Has course branching elastic fibers
• Few collagen fibers
• Elastic fibers are arranged parallel to each other, forming thin sheets of fenestrated membranes
Elastic fibers
• Found in LCT and as course bundles and sheets in dense regular elastic connective tissue
• Made by fibroblasts of CT and by smooth muscle cells in blood vessels
• Fibers contain the protein elastin (lots of glycine, proline, aa’s desmosine, isodesmosine cross-link elastin molecules.
Elastic fibers
• Fibers contain the protein elastin (lots of glycine, proline, aa’s desmosine, isodesmosine cross-link elastin molecules and impart elasticity (can stretch)
• Elastin in fiber core
• Sheath of microfibrils (10 nm), a glycoprotein
Reticular Tissue
• Framework (scaffolding) for liver, adipose tissue, bone marrow, lymph nodes, spleen etc.
• Fibroblasts make type II collagen
Adipose Tissue
• White (unilocular)
- single lipid droplet, capillaries go into ct septa between fat cells.
- Receptors for insulin, growth hormone, norepinephrine, glucocorticoids
- Subcutaneous, in masses around the body
Adipose Tissue
• Brown (multilocular)
• Multiple droplets
• Many mitochondria with cytochromes, lots of bv near the adipocytes
• In human infants around the neck and interscapular region (?around eyes?)
Formation of adipocytes
• Mesenchyme, may be a specific adipocyte precursor cell
• Early Fetal: epitheloid precursors
• Late fetal: secondary fat formation from fusiform precursor cells in ct.
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