cheminform abstract: enzyme-catalyzed asymmetrization of 2,2-disubstituted 1,3-propanediols using...
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1997 biochemical syntheses, microbiological syntheses
biochemical syntheses, microbiological synthesesO 0035
38 - 057Enzyme-Catalyzed Asymmetrization of 2,2-Disubstituted 1,3-Propanediols Using 1-Ethoxyvinyl Esters. — The lipase-mediatedasymmetrization of prochiral diols using various 1- ethoxyvinyl esters (I) isstudied. The benzoate ester (Ia) provides good to excellent chemical yieldsand the highest enantioselectivities. — (AKAI, S.; NAKA, T.; TAKEBE, Y.;KITA, Y.; Tetrahedron Lett. 38 (1997) 24, 4243-4246; Fac. Pharm. Sci., OsakaUniv., Suita, Osaka 565, Japan; EN)
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