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C2/D2: Diabetes Care at Kaiser Permanente Population-based Approach
Alide Chase, Senior Vice President, Medicare Clinical Operations & Population Care and Executive Director, Care Management Institute
Objectives
2
• Review a large system’s approach to population-based care with a
focus on pre-diabetes and diabetes
• Appreciate the need to “focus on the few” treatments most
impactful
• Appreciate the use of segmentation to customize approach to
different people’s care needs
• Review the importance of measurement and use of dashboards
from a system level to individual level
• Share successful use of technology to increase compliance and
self care
Today’s Focus
Tactics
1. Prevention
2. Treatment Intensification
3. Prevention of Complications
4. Segmentation
5. Technology
6. Metrics
7. Outcomes
3
Evolution of Population Care
1997 Disease Management 2010 Complete Care
Chronic Conditions
Lifestyle/Behavior
Prevention
Oth
er D
isea
ses
Co
ron
ary
Art
ery
Dis
ease
Dys
lipid
emia
Dia
bet
es
Old Days New Approach
4
5
NEW THINKING: Population Care “Complete Care”
Key themes People
Patient centered care and focus
Make the right thing easier to do
Get the right person to do the right job
Need for sponsorship at all levels
6
Systems
Focus on “what” needs to be improved
Metrics
Integration of members of the healthcare team
Emphasis on process improvement techniques
Technology
Electronic Medical Record: Delivering the right information at the right time
Registries
Panel management tools
Web and smart phone applications
Interactive voice responses
Diabetes Basics and Facts
7
8
Diabetes Basics
Most diabetes develops in people with inherent insulin resistance (high prevalence in the Middle Eastern
population) Obesity adds to the risk due to excess food and lack
of exercise This leads to:
• Cardiovascular disease (heart attacks & strokes) and
• Hyperglycemia (excessive blood sugar) which can lead to blindness, kidney failure, amputations, and coma
Middle East & North Africa Diabetes Facts
IDF estimates suggest that one in five people in the Middle East are now living with diabetes, a number expected to increase to 1 in every 3 by 2030*
• Two out of every five respondents are at risk of developing diabetes,. However, almost 40% of those at risk have never had a blood glucose test**.
Six out of the world’s top ten countries for highest prevalence of diabetes are in the Middle East and North Africa Region
Kuwait, Lebanon, Qatar, Saudi Arabia, Bahrain and the United Arab Emirates ranks #2 in the world at 19.5% prevalence ***.
The region spends $5.5 billion annually treating diabetes****
9
*International Diabetes Federation’s (IDF) World Diabetes Congress (WDC)
** Novo Nordisk’s diabetes awareness survey in the MENA region November 2010
***PLoS One. 2012; 7(8): e40948
**** International Diabetes Foundation 2012 fifth edition
Why Behavior Change Now? Kaiser Permanente diabetes burden to surge over time
Pre-diabetes
20121
1.67 million
1 – Preliminary data; CMI Analysis October 2012. Pre-diabetes defined according to ADA definition using lab values.
2 – Diabetes Prevention Research Group; Diabetes Prevention Program
3 – Preliminary data; CMI Analysis, as of March 31 2012. CORE KP HEDIS Diabetes cohort, minus expected % of Type 1 diabetes per CDC national prevalence
4 – Based on average annual medical expenditure estimates, Vojta et al, Hlth Aff, Jan 2012. Effective Interventions for Stemming Diabetes and Pre-Diabetes
New cases of diabetes by 2015
482,630
New cases of diabetes by 2022
868,400
= $6.3 B/year4
29% develop diabetes over 3 years2
52% develop diabetes over 10 years2
KP members with type 2 DM in 20123
477,383
= $3.48 B/year4
10
How does KP Apply a Population-based Approach to Diabetes Care?
11
• Prevention of both Pre-Diabetes and Diabetes (DM):
Weight control & exercise
• Prevention and Treatment of DM complications:
“focus on the few” most impactful treatments
customize approach
measurement (metrics) and dashboards from a system to individual level
Use technology
12
Kaiser Permanente’s Approach
Total Population l
Obesity
Complicated
Uncomplicated
Diabetes
Population View with Sub-Populations
• 8% KP
• 11-20% ME
• 20% KP
• ME 40%, but ½ not tested
Pre-Diabetes
To Prevent Pre-DM and DM Evidence: Decrease weight and increase exercise in obese and
pre-diabetes individuals prevents diabetes
• The Diabetes Prevention Trial (DPT) showed that a combination of:
150 min of exercise and 7% weight loss will lead to 30% less progression of pre- diabetes in 10 yrs. as compared to Metformin, an oral glucose control medication that led to an 18% reduction in progression to diabetes.
Diabetes may be reduced to pre-diabetes or normal state with weight loss
14
Action: Using Diabetes Programs, educate people how to lose weight and exercise
Approach:
Public health messages on TV & radio; create walking paths, work with schools to remove sugared drinks from vending machines, healthy choices in cafeteria, and promote exercise
Patient Engagement: interactive online education programs, education classes, individual counseling by health coaches and dietitians
Prevention of DM complications: “focus on the few” most impactful treatments
We must know:
• What are the biggest causes of morbidity, mortality and cost of care of diabetes complications?
it is not what most people think
• If treatments are used that decrease morbidity & mortality, then what is the cost of care?
best to model the result with a program like Archimedes
15
Costs of Diabetes Complications
5.1
2.4
1.10.7
0.2
0
1
2
3
4
5
6
MI, Stroke Kidney Disease Coma Amputation Blindness
CVD is the biggest cost of care in diabetes
Unfortunately sugar control doesn’t help
Sugar control [A1C] prevents
Based on Northern Cal KP 1996 data
16
BP & cholesterol treatments decrease
In M
illio
ns $
What Works: BP & Lipid Meds Prevent CVD ACE-I fixed dose
22%
0%
5%
10%
15%
20%
25%
Decreased CVD
17
Heart Protection Study
MRC/BHF Heart Protection Study of cholesterol-
lowering therapy and of antioxidant vitamin
supplementation in a wide range of patients at
increased risk of coronary heart disease death:
early safety and efficacy experience. Eur Heart J
1999;20:725-41.
HOPE Study
Effects of an Angiotensin-Converting–Enzyme
Inhibitor, Ramipril, on Cardiovascular Events
in High-Risk Patients.The Heart Outcomes
Prevention Evaluation Study Investigators
N Engl J Med 2000; 342:145-153
Ful
l Adh
eren
ce
Ful
l Adh
eren
ce
Kaiser Permanente’s ALL Approach
Start all three drugs at fixed dose at once:
• Aspirin,
• Lisinopril or other ACE Inhibitor/ARB
• Lipid Lowering (statins)
In member s with diabetes above age 55 (ASA optional ) and those with CAD
Then repeat BP and Cholesterol test and if still elevated,…
Treat BP & Lipids until normal
18
19
Archimedes Model: Benefit of just starting a fixed dose of ALL
Average annual risk of various events
0
0.005
0.01
0.015
0.02
0.025
0.03
0.035
0.04
0.045
MI Stroke ESRD Blind Dying
Nothing
HbA1c control
ALL
71% decline
Which Segment of the Population with Diabetes do you focus on?
Which segment is easy to identify for treatment with ALL?
• People with diabetes who are over 55 have a 94% chance of having either high BP or cholesterol, * the criteria proven in HOPE to benefit from Lisinopril **
Therefore consider all people with DM over 55 for ALL & treat high BP and cholesterol at any age****
Which people are at highest risk for sugar sensitive complications like blindness amputations and kidney failure?
• The higher the A1C the more likely each of those complications are*** . American Diabetes Association and NCQA both agree HgbA1c should be <9****
All patients should be below Hgb A1C 9, and all should be as near normal as possible without producing significant low blood sugars.
20
* Selby ** Mircohope *** DCCT, **** ADA glucose targets NCQA HEDIS targets
>55yo Use
ALL Meds
Complicated
Diabetes
How do the Few Actions Fit into KP Diabetes:
Step 1, consider ALL medications
Uncomplicated Diabetes
21
ALL Meds
Complicated
Diabetes
Treat to
Target
Then BP, LDL, A1c Ctrl
Kaiser Permanente Diabetes: Step 2 Focus on Treatment
Intensification of the Other 3 Treatments : BP, LDL
Cholesterol, & A1C
Focus on
the Few
Uncomplicated Diabetes
Not in control
22
Technology: Make the “Right Thing” Easier
In-Reach: to patients during clinic visit
• Electronic Medical record organizes the opportunities
• Patient Panels:
Panel Management
Panel support Tool
• In Reach at time of visit: Maximizing use of the medical assistant
Out reach: to patients at home
• Automated electronic contacts
Medication adherence: automated letters & calls
Email:
• Automated lab results
• Patient contacts provider
23
Making the Right Thing Easier
Physician Education
Tools
Panel Support Tool
Physician Member
Visit
HEDIS Performance
24
South Bay Beta Blocker Adherence Program Clinical Strategic Goals Results
CSG Results - Persistence of Beta Blocker Treatment
post Heart Attack
84.0
85.0
86.0
87.0
88.0
89.0
90.0
91.0
92.0
pe
rio
d 1
-
Fe
bru
ary
20
09
pe
rio
d 2
-
Ap
ril 2
00
9
pe
rio
d 3
-
Jun
e 2
00
9
pe
rio
d 4
-
Au
gu
st
20
09
pe
rio
d 5
-
Oct
ob
er
20
09
South Bay
SC REGION
Intern started South
Bay BB adherence
program - June 2009
In-Reach: Electronic Medical Record Data Organization
25
Panel Support Tool
26
A Team Approach to Care
• Identify missing labs, screenings, kp.org status, etc.
• Provide member instructions
• Contact member and document encounter in HealthConnect™
• Vital sign collection & documentation
• Identify and flag alerts for provider
• Prepare patient for exams
• Pre-encounter follow-up
• After visit summary, care instructions, follow-up appt, educational materials, access to kp.org
• Follow-up contact and appointments
27
Outreach: Medication adherence: Refill Call/Letter Reminder
19%
28
Automated Communication: Email - 4.5 Million Members Viewed Their Test Results in 1 year
29
29
Email: 3.1 Million Members Emailed their Doctor
30
And . . . Email Improved OUTCOMES
31
Health Affairs. 2010;29:1370. 31
What Metrics Do We Need at Provider Level to Drive Improvement?
Principle: metrics alone do not decrease diabetes or its complications
• Therefore those that lead to ACTIONS are most important: “ACTIONABLE” is the test of value of use of a metric at any given time
Items to titrate: BP, LDL, Cholesterol, and A1C
Medication dispensed and refilled that are on the “ABC” list : Adherence drops 50% in one year so adherence is a major issue
• Others that are helpful for other preventative measures annually:
Fasting Blood Sugar: to diagnose DM, and following at home glucose testing if results will be ACTIONABLE
Eye exams
Kidney: urine microalbumin,
Nerve: Foot exams
What to display at each level to drive action towards improvement?
32
Metrics: All Start With a Registry
A list of who is in your population that has diabetes
Criteria: usually based on a diagnosis of diabetes or use of medications for sugar control
Optimal to have just a few metrics:
• Best with results of BP, lipids, A1c, and their medications including last refill
This registery & its metrics allow for assessing:
• If BP, lipid, A1C treatments initiation & adherence, and if contact patients by
In-reach: reminders to providers to consider treatment or
Out-reach: reminders to patients to get treatments advised
• Adherence: the percent on a medication over time.
33
For Comparisons with the Nation and Regions, Ambulatory Metrics are used
34
75t h
N on-
PPOs
9 0 t h
N on-
PPOs
HED IS
2 0 12
(PY 2011)
HED IS
A dmin.
'12 3rd Qtr
N ort hern
C alif o rnia
Sout hern
C alif o rnia
C o lorado Georg ia Hawaii M id -
A t lant ic
St at es
N ort hwest
( 9 0 0 3 )2
Ohio
LDL-C Screening 92.70% 94.91% 90th 75th 97.49% 96.51% 94.81% 96.70% 98.92% 95.82% 97.43% 95.23%
LDL-C Level <100 65.82% 72.51% 90th 90th 82.22% 82.26% 81.25% 78.95% 84.49% 78.11% 76.44% 75.18%
Controlling High Blood Pressure 70.90% 75.55% 75th 90th 87.03% 89.47% 83.38% 81.08% 84.85% 85.81% 83.32% 78.43%
Persistence of Beta-Blocker Treatment After a Heart 90.82% 94.25% 90.53% 94.39% 93.45% 84.91% 83.33% 84.67% 94.06% 87.50%
Comprehensive Diabetes Care
HbA1c Testing 93.92% 95.62% 90th 75th 96.99% 97.49% 95.60% 95.14% 98.87% 95.51% 97.62% 94.60%
HbA1c Control >9% (low rate better) 15.93% 11.68% 90th 75th 9.91% 8.74% 15.00% 13.83% 8.49% 10.78% 8.50% 12.60%
HbA1c Control <8% 75.46% 79.51% 79.51% 81.75% 73.33% 74.09% 79.95% 78.59% 80.43% 73.67%
Retinal Exam 74.70% 80.78% 90th 82.18% 85.40% 79.61% 48.38% 86.59% 78.43% 84.05% 70.45%
LDL-C Screening 91.97% 94.38% 96.72% 96.23% 91.55% 95.08% 98.26% 95.29% 96.59% 95.44%
LDL-C Level <100 60.61% 66.43% 90th 90th 79.87% 77.16% 71.91% 69.35% 81.98% 73.98% 72.85% 74.01%
Medical Attention for Nephropathy 92.09% 94.16% 90th 90th 96.82% 97.92% 94.55% 94.72% 95.01% 96.82% 97.38% 96.65%
Blood Pressure Control <140/80 54.01% 63.02% 90th 90th 76.28% 81.34% 72.94% 70.07% 75.22% 76.78% 75.58% 72.37%
Blood Pressure Control <140/90 71.13% 76.64% 90th 90th 86.04% 88.24% 85.87% 81.97% 84.99% 84.50% 83.90% 83.13%
Adult BMI Assessment 80.31% 88.58% 90th 90th 99.00% 98.97% 96.00% 99.00% 95.99% 96.82% 98.27% 94.40%
Breast Cancer Screening - Ages 42-69 75.40% 80.63% 90th 90th 87.93% 90.91% 88.49% 86.21% 81.36% 90.35% 88.06% 84.70%
Colorectal Cancer Screening 68.93% 76.02% 90th 90th 87.90% 87.28% 85.26% 84.97% 82.26% 87.72% 87.29% 86.78%
Most Effective Cardiovascular Care
Cardiovascular
Cholesterol Management for Patients With Cardiovascular Conditions
Diabetes
High Impact Measure - Prevention
Major InitiativesHED IS 2 0 12
N at ' l Percent iles
Programwide
Perf o rmance
HED IS 2 0 12 ( Perf o rmance Y ear 2 0 11)
Kaiser Permanet e
1 2 3 4 5 6 7 8
Outcomes: What Did We Accomplish?
Targeted medication utilization
Intermediate outcomes: how did we do with BP lipid & A1C control compared to the nation?
Targeted outcomes: Heart attacks & strokes
• In the Diabetic & CVD populations using ALL
• Total population in a large region
35
We Achieved >77% Medication Initiation & Adherence on Heart Attack & Stroke Prevention Meds…
85.477.3
% DM Pts in Southern California
Chart Title
On Statin On ACE/ARB
36
Ambulatory Strategic Subscale 2012 (Performance Year 2011) Compared to 2011 National Percentiles
37 DUC 20110211_001
At/above 90th percentile
At/above 75th percentile
Medicare Ambulatory 2012 (Performance Year 2011)
75t h
N on-
PPOs
9 0 t h
N on-
PPOs
HED IS
2 0 11
(PY 2010)
HED IS
2 0 12
(PY 2011)
N ort hern
C alif o rnia
Sout hern
C alif o rnia
C o lorado Georg ia Hawaii M id -
A t lant ic
St at es
N ort hwest
( 9 0 0 3 )2
Ohio
LDL-C Screening 92.22% 94.40% 90th 90th 97.78% 97.67% 98.50% 96.39% 98.84% 95.74% 97.12% 95.86%
LDL-C Level <100 66.38% 72.15% 90th 90th 81.61% 82.57% 86.28% 79.34% 85.55% 78.36% 75.98% 80.54%
Controlling High Blood Pressure 68.86% 74.42% 75th 90th 84.02% 86.37% 88.33% 75.08% 87.83% 85.97% 80.29% 88.81%
Persistence of Beta-Blocker Treatment After a Heart 88.03% 91.58% 90.50% 91.81% 98.61% 70.97% 90.00% 85.54% 90.97% 98.51%
Comprehensive Diabetes Care
HbA1c Testing 93.93% 95.95% 75th 75th 97.76% 97.61% 97.82% 97.32% 98.30% 95.79% 98.29% 96.59%
HbA1c Control >9% (low rate better) 16.11% 11.31% 75th 90th 8.95% 8.66% 10.90% 9.49% 9.73% 11.15% 7.96% 10.71%
HbA1c Control <8% 75.43% 80.18% 79.87% 81.04% 78.50% 76.89% 75.91% 79.85% 81.37% 75.43%
Retinal Exam 73.66% 79.28% 90th 90th 82.43% 83.88% 87.23% 86.37% 85.40% 81.01% 82.97% 87.83%
0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% LDL-C Screening 91.48% 94.07% 75th 75th 98.40% 97.91% 91.90% 97.08% 97.57% 95.43% 96.96% 95.62%
LDL-C Level <100 60.10% 65.37% 90th 90th 84.03% 80.00% 79.44% 73.97% 81.27% 72.56% 73.99% 75.91%
Medical Attention for Nephropathy 91.56% 93.92% 75th 90th 98.40% 97.91% 99.07% 96.84% 96.59% 96.58% 97.31% 94.65%
Blood Pressure Control <140/80* N/A N/A N/A N/A 77.64% 78.66% 77.88% 82.97% 79.56% 72.29% 73.19% 71.78%
Blood Pressure Control <140/90 69.74% 75.06% 75th 90th 90.10% 87.91% 92.21% 91.24% 88.56% 82.01% 81.79% 84.43%
Adult BMI Assessment 65.69% 80.23% 90th 90th 99.00% 98.97% 96.00% 99.00% 95.99% 96.82% 98.27% 94.40%
Breast Cancer Screening - Ages 42-69 75.13% 80.92% 75th 90th 88.55% 89.68% 85.75% 83.43% 89.02% 90.04% 88.78% 86.56%
Colorectal Cancer Screening 68.71% 75.57% 90th 90th 91.30% 88.61% 84.02% 85.59% 78.61% 82.26% 85.65% 86.15%
* First Year M easure HEDIS 2011.
HED IS 2 0 11
N at ' l Percent iles1
Programwide
Perf o rmance
HED IS 2 0 12 ( Perf o rmance Y ear 2 0 11)
Kaiser Permanet e
Cholesterol Management for Patients With Cardiovascular Conditions
Cardiovascular
Diabetes
1 HEDIS 2011 National Percentiles. HEDIS 2012 benchmarks will be available in Aug. for Commercial, Oct. for M edicare.
Major Initiatives
Most Effective Cardiovascular Care
High Impact Measure - Prevention
1 2 3 4 5 6 7 8
Achieved 75th-90th Percentile in Testing and
Treating for AC1C, BP, and Lipid control
37
We Decreased Myocardial Infarcts in Northern California Kaiser Members
38
~60% drop
24% decline
N Engl J Med. 2010;362:2155-65.
38
39
Diabetes & CVD Patients Decreased MI’s & Strokes over 60% with Use of ALL
-15
-26-30
-25
-20
-15
-10
-5
0
Decrese in MI & Strokes/1000 persons/yr
low util
High Util
Even 1 day of 5 utilization was significant, but taking it
2/3 of the time was much more beneficial.
RR 60% decrease
39
Summary
Use a large systems approach to population care
Focus on the “few” who will benefit most using segmentation to find those at highest risk of heart attacks & strokes, and use:
• Simplified, inexpensive “Treat To Target” protocols,
• Registry and dashboard of metrics of medication adherence, BP, cholesterol and A1C to a few targets and corrective action until achieved, and
• Technology, including a panel support tool, proactive office encounter, automatic call/letter reminders, email communication,
KP achieved
• >77% of the critical medication initiation/adherence,
• >75% ile A1C, lipid and bp control compared to the nation, and
• The major outcome of decreasing severe heart attacks & or strokes in >60%
in both the diabetes and entire Northern California population
40
Ask Alide
Questions?
41
Alide Chase
Senior Vice President, Medicare Clinical Operations & Population Care
Executive Director, CMI
alide.l.chase@kp.org, 510-271-5817
Presenter
42
APPENDIX
43
44
Step 1
if >55yo or
CVD start ALL
Step 2
After ALL,
If still high, Add Then add Then add
ASA A: 81-325 1/d
B:BP
meds L: Lisinopril 20 if SBP>140 Prinzide 20/25
Add
Amlodipine Add Atenolol
C: Chol
L: atorvastatin
20-40 if LDL>100 atorvastatin 40 Atorva 80
S: Sugar
Control
Diet &
Exercise
pre meal
Sugar>120 metformin
skip or add
glipizide add Insulin
Treatment Algorithm: ABC's of DM
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