bme 301 lecture seven. poll results question 1: do you support reforming the us health care system...

BME 301

Lecture Seven

Poll Results Question 1: Do you support reforming the US

health care system so that it is a single payer system similar to that of Canada?

Choice 1: yesChoice 2: noChoice 3: I am undecided

Exam I Results Average = Standard Deviation = High grade = Scale:

A = B = C = D =

What to do if score was lower than you hoped? Come see Dr. RRK - Re-examine how you studied!! Can replace lowest hour exam with final exam

grade Extra credit announcements coming soon

Four Questions

What are the major health problems worldwide?

Who pays to solve problems in health care?

How can technology solve health care problems?

How are health care technologies managed?

Start here

How can we use science and technology to solve problems in health care?

Advance to next unit

How do we test and refine innovations? Case studies

Technology Assessment: The Big Picture

Biological plausibility

Clinical Trials

Where do innovations come from?

Patient Outcomes

Societal Outcomes

Early Detection of Cancer Prevention of Infectious Diseases

Technical Feasibility

Science Drives Engineering

Scientific Method

Engineering design

Treatment of Heart Disease

Microorganisms

Immunity

Vaccines

HIV Cost effectiveness

Pre-cancer cancer transformationDetection of Morphologic Changes

Gene Chips – molecular changes

CervixBreast Prostate

The circulatory system

Arteriosclerosis

CABGPTCA

Heart Failure

LVADTransplant

OutcomesCost effectiveness

OutcomesCost effectiveness

Three Case Studies Prevention of infectious disease

HIV/AIDS Early detection of cancer

Cervical Cancer Ovarian Cancer Prostate Cancer

Treatment of heart disease Atherosclerosis and heart attack Heart failure

Today:

The process of developing a new

medical technology

Class Activity #1 – Gene Therapy

Directions: Place the articles in correct chronological order

Contextual clues in the selections Your knowledge of the science of DNA and genes Your recollection of events in the media.

Articles reflect current thought for the time First article published in 1953; the last in 2003 Discuss in group; come to consensus Choose one member of your group to speak

Did your ideas about the sequence match each other?

What clues or events prompted you to make choice? Do not discuss your ideas with other groups

Definitions

What is the difference between science and engineering?

Definitions Science

Body of knowledge about natural phenomena which is:

Well founded Testable

Purpose is to discover, create, confirm, disprove, reorganize, and disseminate statements that accurately describe some portion of physical, chemical, biological world

“Science is the human activity of seeking natural explanations for what we observe in the world around us.”

Definitions Engineering

Systematic design, production and operation of technical systems to meet practical human needs under specified constraints

Time $$ Performance Reliability

“Engineering. . . in a broad sense. . . is applying science in an economic manner to the needs of mankind “

Definitions

What is the difference between science and engineering? Science

Inquiry to better understand world around us No practical goal necessary

Engineering Use of science to solve real world problem in

practical way

Engineering Design Method Fashioning a product made for a

practical goal in the presence of constraints

Six design steps: 1. Identify a need 2. Define the problem (goals, constraints) 3. Gather information 4. Develop solutions 5. Evaluate solutions 6. Communicate results

Papers, patents, marketing

Refine Design

SPECS

FMEA

Example: Ischemic Heart Disease

Science of IHD Engineering solutions for IHD

1. Identify a need 2. Define the problem (goals,

constraints) 3. Gather information 4. Develop solutions 5. Evaluate solutions 6. Communicate results

Journal Article

Patent

www.uspto.gov Diagnostic Imaging Patent

Summary of Lecture 7

Science “Science is the human activity of

seeking natural explanations for what we observe in the world around us.”

Engineering Systematic design, production and

operation of technical systems to meet practical human needs under specified constraints

Six steps of the engineering design method

Assignments Due Next Time

HW3 How to use Medline:

http://www.lib.utexas.edu