bilcare optima a4 en 01 2012
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Determines barrier requirements
Effective packaging cost reduction tool
Best solution for extending shelf life
Reduced development time and cost
Measures effects of independent parameters: temperature, relative humidity and light
Estimates critical factors that determine failure mode Determines threshold values Determines needed barrier property Designs the final blister cavity using SolidWorks 3D Software Simulates Cavity Thinning & Moisture Permeation through FEA Software
Selects the most optimum packaging film
With BilcareOptima™, over-protection is avoided. We do this by placing your product through rigorous evaluation examinations, including our Forced Degradation Study which:
Research Services
BilcareOptima™
Is my packaging material the right choice?Which environmental parameters affect my products stability?How can I define the shelf life of my product? What is the best packaging for my product?How can I avoid “Over-Protection” for my product?
BilcareOptima™ gives you answers to the following questions:
Packaging Solutions, backed by Science
BilcareOptima™
The first scientific packaging development study that identifies the sensitivity profile of the product and recommends optimal packaging in 6 weeks. The highly sophisticated techniques practiced by BilcareOptima™ stand in significant contrast to the current packaging selection methods, which, in most cases, lead to over-protection. Over-protection is generally a consequence of not fully realizing a product‘s true barrier requirement.
Services & Solutions
BilcareOptima™ is a registered trademark of Bilcare Ltd.
Degradation pattern of formulation is evaluated using a set of designed experiments
Three fresh batches are studied under various climatic conditions to evaluate
Hygroscopicity Physical degradation Chemical degradation Drug release properties Hardness & friability Photo sensitivity Gas liberation
The blister is designed and thinning profile is modeled to predict real-life WVTR
BilcareOptima™
Bilcare Research Innovative Blister Films
ensuring optimal packaging
+
Water vapour transmission rate ASTM-1249, tropical conditions 38 °C, 90% r.h. , PVC film 250 mic, g/m² ·d.
Aclar ® 4000
Venus™
0,06
0
0,08Aclar ® 3000 0,08
0,11
Aclar ® 2000 0,11
Aclar ® 900 0,24
Aclar ® 20E 0,27
PVC/PVDC 120 g/m2 0,25
PVC/PVDC 90 g/m2 0,30PVC/PE/PVDC 90 g/m2 0,30
Aclar ® 160 0,35
PVC/PVDC 80 g/m2 0,35
PVC/PE/PVDC 60 g/m2 0,45
PVC/PVDC 40 g/m2 0,65
PVC/PE/PVDC 40 g/m2 0,65
PVC 3,30
130
0,06200
160
PVC/PVDC 60 g/m2 0,45
Research Services
BilcareOptima™
The BilcareOptima™ Methodology
AquaBa® is a registered trademark of Bilcare Research GmbHAclar® is a registered trademark of Honeywell (www.aclar.com)
Pharma PackagingInnovations
01/2012 EN
Bilcare Solutions Pharma Packaging Innovations info.optima.eu@bilcare.com bilcareoptima.com
Packaging Solutions, backed by Science
BilcareOptima™
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