aspects to consider -entry points for infection -infection barrier…barriers -species barriers
Post on 04-Jan-2016
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Possible modes of infection:
- Skin contact- Contact with sensitive areas of the body- Ingestion- Inhalation- Injection into the brain- Transplantation of cells/tissues- Injection of purified protein- Contaminated surgical tools- Mother to child
Membrane as a barrier
Non-polar molecules
Polar molecules ener
gy
waterH2O forms
H-bonds
Bound to water
e=80 e=80e=2
Bacterial Lactose-Proton co-transporter (Lac Permease 1PV7.pdb)
side view top view
R302
R144
E269
E269
R144 H322
E126
R302
First must cross the epithelium, then must get into the blood stream
Blood stream is the fast track.
Moving from place to place outside the blood is slow.
Chapter 9
sensory fieldsmotor areasassociation areas(cortex)
movement (basal, limbic)emotion, learning, memory(amygdala, hippocampus)
movement coordination(cerebellum)
autonomic functions(hypothalamus, midbrain, pons, medulla)
sensory-motor integration(thalamus)
Fig. 9-9
Hematocrit (37-54%)
The hemoglobin (12-17 g/dL)
Red cell count (3.9-5.6·106/mL)and morphology
Total white cell count (4-11·103/mL)and differential count
Platelet count (2-5·105/mL)
Blood as a mechanism of spread of infection
Possible modes of infection:
- Skin contact- Contact with sensitive areas of the body- Ingestion- Inhalation- Injection into the brain- Transplantation of cells/tissues- Injection of purified protein- Contaminated surgical tools- Mother to child
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