antiangiogenic and antitumoral activities of ab
Post on 18-Aug-2015
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Alzheimer’s Disease Pathology
Senile Plaques and CAA Neurofibrillary Tangles
•Vascular factors (high cholesterol level, hypertension) increase the risk of developing AD
•A forms some deposits around blood vessels in AD brains
•What is the effect of A on blood vessels?
Control
A treatmentA treatment
Control
Vascularization
A treatment
Placebo
Blood vessels staining in tumor sections
Placebo
A treatment
Tumor
Tumor
Tumor
Tumor
A1-40
Placebo(Brain tumors)
0
10
20
30
40
50
60
70
80
Control (n=8) Aß1-40 (n=8)
Mic
rov
es
se
l co
un
t
Control
A treatment
Blood vessel staining
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